Publications by authors named "Roberta De Simone"

17Publications

Integration of Multiple Platforms for the Analysis of Multifluorescent Marking Technology Applied to Pediatric GBM and DIPG.

Authors:
Giulia Pericoli Stefania Petrini Ezio Giorda Roberta Ferretti Maria Antonietta Ajmone-Cat Will Court Libenzio Adrian Conti Roberta De Simone Paola Bencivenga Alessia Palma Angela Di Giannatale Chris Jones Andrea Carai Angela Mastronuzzi Emmanuel de Billy Franco Locatelli Maria Vinci

Int J Mol Sci 2020 Sep 15;21(18). Epub 2020 Sep 15.

Department of Onco-Hematology, Cell and Gene Therapy, Bambino Gesù Children's Hospital-IRCCS, 00146 Rome, Italy.

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September 2020

Beneficial Effects of Fingolimod on Social Interaction, CNS and Peripheral Immune Response in the BTBR Mouse Model of Autism.

Authors:
Roberta De Simone Alessia Butera Monica Armida Antonella Pezzola Monica Boirivant Rosa Luisa Potenza Laura Ricceri

Neuroscience 2020 05 27;435:22-32. Epub 2020 Mar 27.

Centre for Behavioural Science and Mental Health, Istituto Superiore di Sanità, Rome, Italy. Electronic address:

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May 2020

Fingolimod: A Disease-Modifier Drug in a Mouse Model of Amyotrophic Lateral Sclerosis.

Authors:
Rosa Luisa Potenza Roberta De Simone Monica Armida Valentina Mazziotti Antonella Pèzzola Patrizia Popoli Luisa Minghetti

Neurotherapeutics 2016 10;13(4):918-927

Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Rome, Italy.

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October 2016

Glycogen synthase kinase 3 is part of the molecular machinery regulating the adaptive response to LPS stimulation in microglial cells.

Authors:
Maria Antonietta Ajmone-Cat Maria Cristina D'Urso Giorgia di Blasio Maria Stefania Brignone Roberta De Simone Luisa Minghetti

Brain Behav Immun 2016 07 22;55:225-235. Epub 2015 Nov 22.

Department of Cell Biology and Neuroscience, Istituto Superiore di Sanità, Rome, Italy. Electronic address:

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July 2016

The mitochondrial uncoupling protein-2 is a master regulator of both M1 and M2 microglial responses.

Authors:
Roberta De Simone Maria Antonietta Ajmone-Cat Manuela Pandolfi Antonietta Bernardo Chiara De Nuccio Luisa Minghetti Sergio Visentin

J Neurochem 2015 Oct 3;135(1):147-56. Epub 2015 Aug 3.

Experimental Neurology Unit, Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Rome, Italy.

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October 2015

Microglial polarization and plasticity: evidence from organotypic hippocampal slice cultures.

Authors:
Maria Antonietta Ajmone-Cat Melissa Mancini Roberta De Simone Piera Cilli Luisa Minghetti

Glia 2013 Oct 5;61(10):1698-711. Epub 2013 Aug 5.

Department of Cell Biology and Neuroscience, Istituto Superiore di Sanità, 00185 Rome, Italy.

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October 2013

The nuclear receptor peroxisome proliferator-activated receptor-γ promotes oligodendrocyte differentiation through mechanisms involving mitochondria and oscillatory Ca2+ waves.

Authors:
Antonietta Bernardo Roberta De Simone Chiara De Nuccio Sergio Visentin Luisa Minghetti

Biol Chem 2013 Dec;394(12):1607-14

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December 2013

Branched-chain amino acids influence the immune properties of microglial cells and their responsiveness to pro-inflammatory signals.

Authors:
Roberta De Simone Federica Vissicchio Cecilia Mingarelli Chiara De Nuccio Sergio Visentin Maria Antonietta Ajmone-Cat Luisa Minghetti

Biochim Biophys Acta 2013 May 9;1832(5):650-9. Epub 2013 Feb 9.

Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Rome, Italy.

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May 2013

Docosahexaenoic acid modulates inflammatory and antineurogenic functions of activated microglial cells.

Authors:
Maria Antonietta Ajmone-Cat Maria Lavinia Salvatori Roberta De Simone Melissa Mancini Stefano Biagioni Antonietta Bernardo Emanuele Cacci Luisa Minghetti

J Neurosci Res 2012 Mar 4;90(3):575-87. Epub 2011 Nov 4.

Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Rome, Italy.

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March 2012

Peroxisome proliferator-activated receptor γ agonists accelerate oligodendrocyte maturation and influence mitochondrial functions and oscillatory Ca(2+) waves.

Authors:
Chiara De Nuccio Antonietta Bernardo Roberta De Simone Enrico Mancuso Valerio Magnaghi Sergio Visentin Luisa Minghetti

J Neuropathol Exp Neurol 2011 Oct;70(10):900-12

Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Rome, Italy.

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October 2011

TGF-β and LPS modulate ADP-induced migration of microglial cells through P2Y1 and P2Y12 receptor expression.

Authors:
Roberta De Simone Cristina Elena Niturad Chiara De Nuccio Maria Antonietta Ajmone-Cat Sergio Visentin Luisa Minghetti

J Neurochem 2010 Oct 30;115(2):450-9. Epub 2010 Aug 30.

Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Rome, Italy.

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October 2010

Microglial activation in chronic neurodegenerative diseases: roles of apoptotic neurons and chronic stimulation.

Authors:
Luisa Minghetti Maria Antonietta Ajmone-Cat Maria Anna De Berardinis Roberta De Simone

Brain Res Brain Res Rev 2005 Apr 18;48(2):251-6. Epub 2005 Jan 18.

Department of Cell Biology and Neurosciences, Istituto Superiore Di Sanità, Italy.

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April 2005

Activation of alpha7 nicotinic acetylcholine receptor by nicotine selectively up-regulates cyclooxygenase-2 and prostaglandin E2 in rat microglial cultures.

Authors:
Roberta De Simone Maria Antonietta Ajmone-Cat Daniela Carnevale Luisa Minghetti

J Neuroinflammation 2005 Jan 25;2(1). Epub 2005 Jan 25.

Department of Cell Biology and Neurosciences, Section of Degenerative and Inflammatory Neurological Diseases, Istituto Superiore di Sanità, Rome, Italy.

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January 2005

Beneficial effects of enriched environment on adolescent rats from stressed pregnancies.

Authors:
Giovanni Laviola Monica Rea Sara Morley-Fletcher Simonetta Di Carlo Antonella Bacosi Roberta De Simone Mario Bertini Roberta Pacifici

Eur J Neurosci 2004 Sep;20(6):1655-64

Section of Behavioural Neuroscience, Department of Cell Biology and Neuroscience, Istituto Superiore di Sanita, Viale Regina Elena, 299, I-00161 Roma, Italy.

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September 2004

Cognitive and neurological deficits induced by early and prolonged basal forebrain cholinergic hypofunction in rats.

Authors:
Laura Ricceri Luisa Minghetti Anna Moles Patrizia Popoli Annamaria Confaloni Roberta De Simone Paola Piscopo Maria Luisa Scattoni Monica di Luca Gemma Calamandrei

Exp Neurol 2004 Sep;189(1):162-72

Section of Behavioural Neurosciences, Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, 00161 Rome, Italy.

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September 2004

Atypical antiinflammatory activation of microglia induced by apoptotic neurons: possible role of phosphatidylserine-phosphatidylserine receptor interaction.

Authors:
Roberta De Simone Maria Antonietta Ajmone-Cat Luisa Minghetti

Mol Neurobiol 2004 Apr;29(2):197-212

Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Italy.

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April 2004

Apoptotic PC12 cells exposing phosphatidylserine promote the production of anti-inflammatory and neuroprotective molecules by microglial cells.

Authors:
Roberta De Simone Maria Antonietta Ajmone-Cat Paola Tirassa Luisa Minghetti

J Neuropathol Exp Neurol 2003 Feb;62(2):208-16

Laboratory of Pathophysiology, Istituto Superiore di Sanità, Rome, Italy.

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February 2003