Publications by authors named "Roberta De Simone"

17Publications

Beneficial Effects of Fingolimod on Social Interaction, CNS and Peripheral Immune Response in the BTBR Mouse Model of Autism.

Neuroscience 2020 05 27;435:22-32. Epub 2020 Mar 27.

Centre for Behavioural Science and Mental Health, Istituto Superiore di Sanità, Rome, Italy. Electronic address:

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May 2020

Fingolimod: A Disease-Modifier Drug in a Mouse Model of Amyotrophic Lateral Sclerosis.

Neurotherapeutics 2016 10;13(4):918-927

Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Rome, Italy.

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October 2016

Glycogen synthase kinase 3 is part of the molecular machinery regulating the adaptive response to LPS stimulation in microglial cells.

Brain Behav Immun 2016 07 22;55:225-235. Epub 2015 Nov 22.

Department of Cell Biology and Neuroscience, Istituto Superiore di Sanità, Rome, Italy. Electronic address:

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July 2016

The mitochondrial uncoupling protein-2 is a master regulator of both M1 and M2 microglial responses.

J Neurochem 2015 Oct 3;135(1):147-56. Epub 2015 Aug 3.

Experimental Neurology Unit, Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Rome, Italy.

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October 2015

Microglial polarization and plasticity: evidence from organotypic hippocampal slice cultures.

Glia 2013 Oct 5;61(10):1698-711. Epub 2013 Aug 5.

Department of Cell Biology and Neuroscience, Istituto Superiore di Sanità, 00185 Rome, Italy.

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October 2013

TGF-β and LPS modulate ADP-induced migration of microglial cells through P2Y1 and P2Y12 receptor expression.

J Neurochem 2010 Oct 30;115(2):450-9. Epub 2010 Aug 30.

Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Rome, Italy.

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October 2010

Microglial activation in chronic neurodegenerative diseases: roles of apoptotic neurons and chronic stimulation.

Brain Res Brain Res Rev 2005 Apr 18;48(2):251-6. Epub 2005 Jan 18.

Department of Cell Biology and Neurosciences, Istituto Superiore Di Sanità, Italy.

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April 2005

Activation of alpha7 nicotinic acetylcholine receptor by nicotine selectively up-regulates cyclooxygenase-2 and prostaglandin E2 in rat microglial cultures.

J Neuroinflammation 2005 Jan 25;2(1). Epub 2005 Jan 25.

Department of Cell Biology and Neurosciences, Section of Degenerative and Inflammatory Neurological Diseases, Istituto Superiore di Sanità, Rome, Italy.

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January 2005

Beneficial effects of enriched environment on adolescent rats from stressed pregnancies.

Eur J Neurosci 2004 Sep;20(6):1655-64

Section of Behavioural Neuroscience, Department of Cell Biology and Neuroscience, Istituto Superiore di Sanita, Viale Regina Elena, 299, I-00161 Roma, Italy.

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September 2004

Cognitive and neurological deficits induced by early and prolonged basal forebrain cholinergic hypofunction in rats.

Exp Neurol 2004 Sep;189(1):162-72

Section of Behavioural Neurosciences, Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, 00161 Rome, Italy.

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September 2004

Atypical antiinflammatory activation of microglia induced by apoptotic neurons: possible role of phosphatidylserine-phosphatidylserine receptor interaction.

Mol Neurobiol 2004 Apr;29(2):197-212

Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Italy.

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April 2004