Robert Zivadinov

Robert Zivadinov

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Robert Zivadinov

Publications by authors named "Robert Zivadinov"

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Atrophied Brain T2 Lesion Volume at MRI Is Associated with Disability Progression and Conversion to Secondary Progressive Multiple Sclerosis.

Radiology 2019 Nov 24;293(2):424-433. Epub 2019 Sep 24.

From the Buffalo Neuroimaging Analysis Center (A.V.G., J.H., N.B., D.J., M.G.D., D.P.R., R.Z.) and Jacobs MS Center (A.A.L., D.H., C.K.), Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, 100 High St, Buffalo, NY 14203; Institute of Radiology, Department of Clinical Surgical Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy (A.V.G.); and Center for Biomedical Imaging at Clinical Translational Science Institute (M.G.D., B.W., R.Z.), University at Buffalo, State University of New York, Buffalo, NY.

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http://dx.doi.org/10.1148/radiol.2019190306DOI Listing
November 2019

A Preliminary Study of Early-Onset Dementia of Former Professional Football and Hockey Players.

J Head Trauma Rehabil 2018 Sep/Oct;33(5):E1-E8

Departments of Psychiatry (Dr Willer), Neurology (Dr Zivadinov), Orthopedics and Sports Medicine (Drs Haider and Leddy), Biostatistics (Miecznikowski), School of Medicine and Biomedical Sciences, University at Buffalo, New York.

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http://Insights.ovid.com/crossref?an=00001199-900000000-9946
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http://dx.doi.org/10.1097/HTR.0000000000000421DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126972PMC
October 2019

An Exploratory Study of Mild Cognitive Impairment of Retired Professional Contact Sport Athletes.

J Head Trauma Rehabil 2018 Sep/Oct;33(5):E16-E23

UBMD Department of Orthopaedics and Sports Medicine (Drs Baker, Leddy, Haider, Shucard and Sharma), Department of Nuclear Medicine (Dr Baker), Department of Psychiatry (Drs Hinds, Hernandez, and Willer), Department of Neurology (Dr Zivadinov), and Department of Internal Medicine (Dr Durinka), School of Medicine and Biomedical Sciences, State University of New York at Buffalo.

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http://dx.doi.org/10.1097/HTR.0000000000000420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126937PMC
October 2019

Multimodal Imaging of Retired Professional Contact Sport Athletes Does Not Provide Evidence of Structural and Functional Brain Damage.

J Head Trauma Rehabil 2018 Sep/Oct;33(5):E24-E32

Buffalo Neuroimaging Analysis Center, Department of Neurology (Drs Zivadinov, Polak, Schweser, Bergsland, Hagemeier, Dwyer, and Ramasamy), MR Imaging Clinical and Translational Research Center (Drs Zivadinov and Schweser), Department of Orthopaedics (Drs Baker and Leddy), Department of Nuclear Medicine (Dr Baker), and Department of Psychiatry (Dr Willer), Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York, Buffalo.

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http://dx.doi.org/10.1097/HTR.0000000000000422DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126951PMC
October 2019

Serum neurofilament light chain level associations with clinical and cognitive performance in multiple sclerosis: A longitudinal retrospective 5-year study.

Mult Scler 2019 Oct 15:1352458519881428. Epub 2019 Oct 15.

Jacobs MS Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA.

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http://dx.doi.org/10.1177/1352458519881428DOI Listing
October 2019

Response heterogeneity to home-based restorative cognitive rehabilitation in multiple sclerosis: An exploratory study.

Mult Scler Relat Disord 2019 Sep 22;34:103-111. Epub 2019 Jun 22.

Jacobs Multiple Sclerosis Center, Department of Neurology, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.msard.2019.06.026DOI Listing
September 2019

Salient Central Lesion Volume: A Standardized Novel Fully Automated Proxy for Brain FLAIR Lesion Volume in Multiple Sclerosis.

J Neuroimaging 2019 Sep 1;29(5):615-623. Epub 2019 Jul 1.

Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, Buffalo, NY.

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http://dx.doi.org/10.1111/jon.12650DOI Listing
September 2019

Serum neurofilament light chain levels associations with gray matter pathology: a 5-year longitudinal study.

Ann Clin Transl Neurol 2019 Sep 22;6(9):1757-1770. Epub 2019 Aug 22.

Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York.

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http://dx.doi.org/10.1002/acn3.50872DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764487PMC
September 2019

Lipoprotein(a) Levels Are Associated with the Size of Extracranial Arteries in Multiple Sclerosis.

J Vasc Res 2019 Sep 5:1-8. Epub 2019 Sep 5.

Department of Pharmaceutical Sciences, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York, USA,

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http://dx.doi.org/10.1159/000502115DOI Listing
September 2019

Teriflunomide's effect on humoral response to Epstein-Barr virus and development of cortical gray matter pathology in multiple sclerosis.

Mult Scler Relat Disord 2019 Sep 9;36:101388. Epub 2019 Sep 9.

Jacobs Multiple Sclerosis Center, Department of Neurology, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, United States.

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http://dx.doi.org/10.1016/j.msard.2019.101388DOI Listing
September 2019

Targeting Iron Dyshomeostasis for Treatment of Neurodegenerative Disorders.

CNS Drugs 2019 Sep 25. Epub 2019 Sep 25.

Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, 100 High St., Buffalo, NY, 14203, USA.

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http://dx.doi.org/10.1007/s40263-019-00668-6DOI Listing
September 2019

Altered nuclei-specific thalamic functional connectivity patterns in multiple sclerosis and their associations with fatigue and cognition.

Mult Scler 2019 Aug 13;25(9):1243-1254. Epub 2018 Jul 13.

Department of Neurology, Buffalo Neuroimaging Analysis Center, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York, Buffalo, NY, USA.

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http://dx.doi.org/10.1177/1352458518788218DOI Listing
August 2019

Network Dynamics and Cognitive Impairment in Multiple Sclerosis: Functional MRI-based Decoupling of Complex Relationships.

Radiology 2019 Aug 25;292(2):458-459. Epub 2019 Jun 25.

From the Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, 100 High St, Buffalo, NY 14203; and Center for Biomedical Imaging at the Clinical Translational Science Institute, University at Buffalo, State University of New York, Buffalo, NY.

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http://dx.doi.org/10.1148/radiol.2019191125DOI Listing
August 2019

Cumulative gadodiamide administration leads to brain gadolinium deposition in early MS.

Neurology 2019 Aug 8;93(6):e611-e623. Epub 2019 Jul 8.

From the Buffalo Neuroimaging Analysis Center (R.Z., N.B., J.H., D.P.R.) and Jacobs Comprehensive MS Treatment and Research Center (C.K., B.W.-G., D.H.), Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, and Center for Biomedical Imaging at Clinical Translational Science Institute (R.Z., M.G.D., F.S.), University at Buffalo, State University of New York.

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http://dx.doi.org/10.1212/WNL.0000000000007892DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709999PMC
August 2019

Preserved network functional connectivity underlies cognitive reserve in multiple sclerosis.

Hum Brain Mapp 2019 Aug 24. Epub 2019 Aug 24.

Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York (SUNY), Buffalo, New York.

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http://dx.doi.org/10.1002/hbm.24768DOI Listing
August 2019

Aging and Brain Atrophy in Multiple Sclerosis.

J Neuroimaging 2019 Jul 10;29(4):527-535. Epub 2019 May 10.

Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY.

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http://dx.doi.org/10.1111/jon.12625DOI Listing
July 2019

Oxysterols and apolipoproteins in multiple sclerosis: a 5 year follow-up study.

J Lipid Res 2019 Jul 13;60(7):1190-1198. Epub 2019 May 13.

Departments of Pharmaceutical Sciences University at Buffalo, The State University of New York, Buffalo, NY

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http://dx.doi.org/10.1194/jlr.M089664DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602132PMC
July 2019

Ventral posterior substantia nigra iron increases over 3 years in Parkinson's disease.

Mov Disord 2019 07 10;34(7):1006-1013. Epub 2019 Jun 10.

Movement Disorder Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York, USA.

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http://dx.doi.org/10.1002/mds.27730DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642003PMC
July 2019

Abnormal venous postural control: multiple sclerosis-specific change related to gray matter pathology or age-related neurodegenerative phenomena?

Clin Auton Res 2019 Jun 17;29(3):329-338. Epub 2018 Aug 17.

Department of Neurology, Buffalo Neuroimaging Analysis Center, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, 100 High Street, Buffalo, NY, 142013, USA.

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http://dx.doi.org/10.1007/s10286-018-0555-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378143PMC
June 2019

Epidemiology and treatment of multiple sclerosis in elderly populations.

Nat Rev Neurol 2019 Jun;15(6):329-342

Jacobs Multiple Sclerosis Center for Treatment and Research, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, State University of New York (SUNY), Buffalo, NY, USA.

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http://dx.doi.org/10.1038/s41582-019-0183-3DOI Listing
June 2019

Lifestyle-based modifiable risk factors in multiple sclerosis: review of experimental and clinical findings.

Neurodegener Dis Manag 2019 Jun 22;9(3):149-172. Epub 2019 May 22.

Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine & Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY 14203, USA.

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http://dx.doi.org/10.2217/nmt-2018-0046DOI Listing
June 2019

No association between variations in extracranial venous anatomy and clinical outcomes in multiple sclerosis patients over 5 years.

BMC Neurol 2019 Jun 11;19(1):121. Epub 2019 Jun 11.

Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA.

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http://dx.doi.org/10.1186/s12883-019-1350-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560860PMC
June 2019

Trait Conscientiousness predicts rate of brain atrophy in multiple sclerosis.

Mult Scler 2019 Jun 20:1352458519858605. Epub 2019 Jun 20.

Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York (SUNY), Buffalo, NY, USA/ Center for Biomedical Imaging, Clinical and Translational Science Institute, University at Buffalo, The State University of New York (SUNY), Buffalo, NY, USA.

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http://dx.doi.org/10.1177/1352458519858605DOI Listing
June 2019

High-density lipoprotein cholesterol is associated with multiple sclerosis fatigue: A fatigue-metabolism nexus?

J Clin Lipidol 2019 Jul - Aug;13(4):654-663.e1. Epub 2019 Jun 18.

Department of Biotechnical and Clinical Laboratory Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA; Department of Pharmaceutical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA.

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http://dx.doi.org/10.1016/j.jacl.2019.06.003DOI Listing
June 2019

Vascular aspects of multiple sclerosis: emphasis on perfusion and cardiovascular comorbidities.

Expert Rev Neurother 2019 May 10;19(5):445-458. Epub 2019 May 10.

a Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences , University at Buffalo, State University of New York , Buffalo , NY , USA.

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https://www.tandfonline.com/doi/full/10.1080/14737175.2019.1
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http://dx.doi.org/10.1080/14737175.2019.1610394DOI Listing
May 2019

Cognitive Profiles of Aging in Multiple Sclerosis.

Front Aging Neurosci 2019 10;11:105. Epub 2019 May 10.

Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo - The State University of New York, Buffalo, NY, United States.

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https://www.frontiersin.org/article/10.3389/fnagi.2019.00105
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http://dx.doi.org/10.3389/fnagi.2019.00105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524468PMC
May 2019

Pathological cut-offs of global and regional brain volume loss in multiple sclerosis.

Mult Scler 2019 04 16;25(4):541-553. Epub 2017 Nov 16.

Department of Neurology and Center of Clinical Neuroscience, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic.

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http://dx.doi.org/10.1177/1352458517742739DOI Listing
April 2019

Characterization of leptomeningeal inflammation in rodent experimental autoimmune encephalomyelitis (EAE) model of multiple sclerosis.

Exp Neurol 2019 Apr 23;314:82-90. Epub 2019 Jan 23.

Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA; Center for Biomedical Imaging at Clinical Translational Science Institute, University at Buffalo, State University of New York, Buffalo, NY, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00144886193001
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http://dx.doi.org/10.1016/j.expneurol.2019.01.013DOI Listing
April 2019

Dietary and lifestyle factors in multiple sclerosis progression: results from a 5-year longitudinal MRI study.

J Neurol 2019 Apr 13;266(4):866-875. Epub 2019 Feb 13.

Department of Neurology, Buffalo Neuroimaging Analysis Center, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, 100 High Street, Buffalo, NY, 142013, USA.

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http://dx.doi.org/10.1007/s00415-019-09208-0DOI Listing
April 2019

Coagulation Pathways in Neurological Diseases: Multiple Sclerosis.

Front Neurol 2019 24;10:409. Epub 2019 Apr 24.

Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, Buffalo Neuroimaging Analysis Center, University at Buffalo, State University of New York, Buffalo, NY, United States.

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http://dx.doi.org/10.3389/fneur.2019.00409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491577PMC
April 2019

The role of Epstein-Barr virus in multiple sclerosis: from molecular pathophysiology to imaging.

Neural Regen Res 2019 Mar;14(3):373-386

Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences; Center for Biomedical Imaging at Clinical Translational Science Institute, University at Buffalo, State University of New York, Buffalo, NY, USA.

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http://www.nrronline.org/text.asp?2019/14/3/373/245462
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http://dx.doi.org/10.4103/1673-5374.245462DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334604PMC
March 2019

Effect of Teriflunomide and Dimethyl Fumarate on Cortical Atrophy and Leptomeningeal Inflammation in Multiple Sclerosis: A Retrospective, Observational, Case-Control Pilot Study.

J Clin Med 2019 Mar 12;8(3). Epub 2019 Mar 12.

Jacobs Multiple Sclerosis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY 14203, USA.

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http://dx.doi.org/10.3390/jcm8030344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463015PMC
March 2019

Establishing pathological cut-offs for lateral ventricular volume expansion rates.

Neuroimage Clin 2018 7;18:494-501. Epub 2018 Feb 7.

Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA.

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http://dx.doi.org/10.1016/j.nicl.2018.02.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842310PMC
February 2019

Assessment of mesoscopic properties of deep gray matter iron through a model-based simultaneous analysis of magnetic susceptibility and R* - A pilot study in patients with multiple sclerosis and normal controls.

Neuroimage 2019 02 14;186:308-320. Epub 2018 Nov 14.

Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo, The State University of New York, 100 High Street, Buffalo, NY, 14202, USA; Center for Biomedical Imaging, Clinical and Translational Science Institute at the University at Buffalo, The State University of New York, 875 Ellicott Street, Buffalo, NY, 14202, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuroimage.2018.11.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481304PMC
February 2019

Higher EBV response is associated with more severe gray matter and lesion pathology in relapsing multiple sclerosis patients: A case-controlled magnetization transfer ratio study.

Mult Scler 2019 Feb 13:1352458519828667. Epub 2019 Feb 13.

Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York, Buffalo, NY, USA/ Center for Biomedical Imaging, Clinical and Translational Science Institute, University at Buffalo, The State University of New York, Buffalo, NY, USA.

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http://dx.doi.org/10.1177/1352458519828667DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692251PMC
February 2019

Changes of deep gray matter magnetic susceptibility over 2 years in multiple sclerosis and healthy control brain.

Neuroimage Clin 2018 13;18:1007-1016. Epub 2017 Apr 13.

Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York, Buffalo, NY, USA.

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http://dx.doi.org/10.1016/j.nicl.2017.04.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984575PMC
January 2019

Susceptibility Weighted MRI in Rodents at 9.4 T.

Methods Mol Biol 2018 ;1718:205-234

Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York, Buffalo, NY, USA.

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http://dx.doi.org/10.1007/978-1-4939-7531-0_13DOI Listing
January 2019

Teriflunomide's Effect on Glia in Experimental Demyelinating Disease: A Neuroimaging and Histologic Study.

J Neuroimaging 2019 Jan 19;29(1):52-61. Epub 2018 Sep 19.

Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY.

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http://dx.doi.org/10.1111/jon.12561DOI Listing
January 2019

Impact of fingolimod on clinical and magnetic resonance imaging outcomes in routine clinical practice: A retrospective analysis of the multiple sclerosis, clinical and MRI outcomes in the USA (MS-MRIUS) study.

Mult Scler Relat Disord 2019 Jan 3;27:65-73. Epub 2018 Oct 3.

Jacobs Multiple Sclerosis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.msard.2018.09.037DOI Listing
January 2019

Plasma levels of soluble NCAM in multiple sclerosis.

J Neurol Sci 2019 01 28;396:36-41. Epub 2018 Oct 28.

Department of Biomedical and Specialty Surgical Sciences, University of Ferrara, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0022510X183043
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http://dx.doi.org/10.1016/j.jns.2018.10.023DOI Listing
January 2019

Lower self-report fatigue in multiple sclerosis is associated with localized white matter tract disruption between amygdala, temporal pole, insula, and other connected structures.

Mult Scler Relat Disord 2019 Jan 9;27:298-304. Epub 2018 Nov 9.

Jacobs Multiple Sclerosis Center for Treatment and Research, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York (SUNY), Buffalo, NY, USA; Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York (SUNY), Buffalo, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.msard.2018.11.005DOI Listing
January 2019

Trait Conscientiousness predicts rate of longitudinal SDMT decline in multiple sclerosis.

Mult Scler 2019 Jan 7:1352458518820272. Epub 2019 Jan 7.

Jacobs Multiple Sclerosis Center, Department of Neurology, School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York, Buffalo, NY, USA.

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http://dx.doi.org/10.1177/1352458518820272DOI Listing
January 2019

Lower total cerebral arterial flow contributes to cognitive performance in multiple sclerosis patients.

Mult Scler 2019 Jan 9:1352458518819608. Epub 2019 Jan 9.

Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York, Buffalo, NY, USA/Center for Biomedical Imaging, Clinical Translational Science Institute, University at Buffalo, The State University of New York, Buffalo, NY, USA.

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http://dx.doi.org/10.1177/1352458518819608DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616024PMC
January 2019

Decrease in Secondary Neck Vessels in Multiple Sclerosis: A 5-year Longitudinal Magnetic Resonance Angiography Study.

Curr Neurovasc Res 2019 ;16(3):215-223

Buffalo Neuroimaging Analysis Center (BNAC), Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, United States.

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http://dx.doi.org/10.2174/1567202616666190612111127DOI Listing
January 2019

Quantitative susceptibility mapping (QSM) with an extended physical model for MRI frequency contrast in the brain: a proof-of-concept of quantitative susceptibility and residual (QUASAR) mapping.

NMR Biomed 2018 12 24;31(12):e3999. Epub 2018 Sep 24.

Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York, New York, USA.

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http://dx.doi.org/10.1002/nbm.3999DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296773PMC
December 2018

Fatigue at enrollment predicts EDSS worsening in the New York State Multiple Sclerosis Consortium.

Mult Scler 2018 Dec 3:1352458518816619. Epub 2018 Dec 3.

New York State Multiple Sclerosis Consortium, Buffalo, NY, USA/Jacobs MS Center for Treatment and Research, Buffalo, NY, USA/ Department of Neurology, University at Buffalo, Buffalo, NY, USA.

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http://dx.doi.org/10.1177/1352458518816619DOI Listing
December 2018

Interferon β for Multiple Sclerosis.

Cold Spring Harb Perspect Med 2018 11 1;8(11). Epub 2018 Nov 1.

Jacobs MS Center, Department of Neurology, University at Buffalo, State University of New York, Buffalo, New York 14202.

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http://dx.doi.org/10.1101/cshperspect.a032003DOI Listing
November 2018

Brain Iron at Quantitative MRI Is Associated with Disability in Multiple Sclerosis.

Radiology 2018 11 17;289(2):487-496. Epub 2018 Jul 17.

From the Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences (R.Z., E.T., N.B., J.H., F.L., M.G.D., E.C., D.R., J.D., F.S.), Center for Biomedical Imaging, Clinical Translational Science Institute (R.Z.), and Jacobs Multiple Sclerosis Center, Department of Neurology, School of Medicine and Biomedical Sciences (C.K., D.H., B.W.G.), University at Buffalo, State University of New York, 100 High St, Buffalo, NY 14203.

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http://dx.doi.org/10.1148/radiol.2018180136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219694PMC
November 2018

Extracranial Veins in Multiple Sclerosis: Is There a Role for Vascular Surgery?

Eur J Vasc Endovasc Surg 2018 Nov 23;56(5):618-621. Epub 2018 Jul 23.

Buffalo Neuroimaging Analysis Centre, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, NY, USA; Centre for Biomedical Imaging at the Clinical Translational Science Institute, State University of New York at Buffalo, NY, USA.

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http://dx.doi.org/10.1016/j.ejvs.2018.06.028DOI Listing
November 2018

Atrophied brain lesion volume, a magnetic resonance imaging biomarker for monitoring neurodegenerative changes in multiple sclerosis.

Quant Imaging Med Surg 2018 Nov;8(10):979-983

Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA.

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http://dx.doi.org/10.21037/qims.2018.11.01DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288055PMC
November 2018

Thalamic white matter in multiple sclerosis: A combined diffusion-tensor imaging and quantitative susceptibility mapping study.

Hum Brain Mapp 2018 10 19;39(10):4007-4017. Epub 2018 Jun 19.

Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York.

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http://doi.wiley.com/10.1002/hbm.24227
Publisher Site
http://dx.doi.org/10.1002/hbm.24227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128742PMC
October 2018

Increased CCL18 plasma levels are associated with neurodegenerative MRI outcomes in multiple sclerosis patients.

Mult Scler Relat Disord 2018 Oct 7;25:37-42. Epub 2018 Jul 7.

Jacobs Comprehensive MS Treatment and Research Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA; Department of Pharmaceutical Sciences, State University of New York, Buffalo, NY, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22110348183021
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http://dx.doi.org/10.1016/j.msard.2018.07.009DOI Listing
October 2018

Walking disability measures in multiple sclerosis patients: Correlations with MRI-derived global and microstructural damage.

J Neurol Sci 2018 10 23;393:128-134. Epub 2018 Aug 23.

Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA; Center for Biomedical Imaging at Clinical Translational Science Institute, University at Buffalo, State University of New York, Buffalo, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2018.08.020DOI Listing
October 2018

White matter tract network disruption explains reduced conscientiousness in multiple sclerosis.

Hum Brain Mapp 2018 09 8;39(9):3682-3690. Epub 2018 May 8.

Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York (SUNY), Buffalo, New York.

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http://dx.doi.org/10.1002/hbm.24203DOI Listing
September 2018

Atrophied Brain Lesion Volume: A New Imaging Biomarker in Multiple Sclerosis.

J Neuroimaging 2018 09 1;28(5):490-495. Epub 2018 Jun 1.

Center for Biomedical Imaging, Clinical and Translational Science Institute, University at Buffalo, The State University of New York, Buffalo, NY.

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http://dx.doi.org/10.1111/jon.12527DOI Listing
September 2018

No evidence of disease activity in patients receiving fingolimod at private or academic centers in clinical practice: a retrospective analysis of the multiple sclerosis, clinical, and magnetic resonance imaging outcomes in the USA (MS-MRIUS) study.

Curr Med Res Opin 2018 08 12;34(8):1431-1440. Epub 2018 Apr 12.

j State University of New York at Buffalo, Jacobs Multiple Sclerosis Center for Treatment and Research, Jacobs Pediatric Multiple Sclerosis Center of Excellence, New York State Multiple Sclerosis Consortium , Buffalo , NY , USA.

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http://dx.doi.org/10.1080/03007995.2018.1458708DOI Listing
August 2018

The Effect of Glatiramer Acetate on Retinal Nerve Fiber Layer Thickness in Patients with Relapsing-Remitting Multiple Sclerosis: A Longitudinal Optical Coherence Tomography Study.

CNS Drugs 2018 08;32(8):763-770

Department of Neurology, School of Medicine and Biomedical Sciences, Jacobs Multiple Sclerosis Center, University at Buffalo, State University of New York, Buffalo, NY, USA.

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http://dx.doi.org/10.1007/s40263-018-0521-9DOI Listing
August 2018

Jugular Venous Flow Quantification Using Doppler Sonography.

Ultrasound Med Biol 2018 08 18;44(8):1762-1769. Epub 2018 May 18.

Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York, USA; Center for Biomedical Imaging at Clinical Translational Science Institute, University at Buffalo, State University of New York, Buffalo, New York, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ultrasmedbio.2018.04.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026550PMC
August 2018

Why Is Cognitive Impairment Present in Multiple Sclerosis? Insights from Functional MRI.

Authors:
Robert Zivadinov

Radiology 2018 08 22;288(2):552-553. Epub 2018 May 22.

From the Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences; and Center for Biomedical Imaging at the Clinical Translational Science Institute, University at Buffalo, State University of New York, 100 High St, Buffalo, NY 14203.

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http://dx.doi.org/10.1148/radiol.2018180719DOI Listing
August 2018

Iron-related gene variants and brain iron in multiple sclerosis and healthy individuals.

Neuroimage Clin 2018 8;17:530-540. Epub 2017 Nov 8.

Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York, Buffalo, NY, USA.

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http://dx.doi.org/10.1016/j.nicl.2017.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699896PMC
July 2018

Fingolimod's Impact on MRI Brain Volume Measures in Multiple Sclerosis: Results from MS-MRIUS.

J Neuroimaging 2018 07 11;28(4):399-405. Epub 2018 May 11.

Jacobs Multiple Sclerosis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York, Buffalo, NY.

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http://dx.doi.org/10.1111/jon.12518DOI Listing
July 2018

Reply: Don't Leave the Back Door Open.

JACC Cardiovasc Interv 2018 07;11(14):1420

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http://dx.doi.org/10.1016/j.jcin.2018.05.011DOI Listing
July 2018

Neurological software tool for reliable atrophy measurement (NeuroSTREAM) of the lateral ventricles on clinical-quality T2-FLAIR MRI scans in multiple sclerosis.

Neuroimage Clin 2017 19;15:769-779. Epub 2017 Jun 19.

Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA; MR Imaging Clinical Translational Research Center, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA.

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http://dx.doi.org/10.1016/j.nicl.2017.06.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496213PMC
June 2018

Gray matter atrophy patterns in multiple sclerosis: A 10-year source-based morphometry study.

Neuroimage Clin 2018 5;17:444-451. Epub 2017 Nov 5.

Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA.

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http://dx.doi.org/10.1016/j.nicl.2017.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684496PMC
June 2018

The Role of High-Frequency MRI Monitoring in the Detection of Brain Atrophy in Multiple Sclerosis.

J Neuroimaging 2018 05 27;28(3):328-337. Epub 2018 Feb 27.

Department of Radiodiagnostic, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic.

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http://dx.doi.org/10.1111/jon.12505DOI Listing
May 2018

Preliminary investigation of cognitive function in aged multiple sclerosis patients: Challenges in detecting comorbid Alzheimer's disease.

Mult Scler Relat Disord 2018 May 13;22:52-56. Epub 2018 Mar 13.

Department of Neurology, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York (SUNY), Buffalo, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.msard.2018.03.008DOI Listing
May 2018

Effect of teriflunomide on gray and white matter brain pathology in multiple sclerosis using volumetric and diffusion-tensor imaging MRI measures.

J Neurol Sci 2018 05 17;388:175-181. Epub 2018 Mar 17.

Jacobs Multiple Sclerosis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA.

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http://dx.doi.org/10.1016/j.jns.2018.03.028DOI Listing
May 2018

Effect of switching from glatiramer acetate 20 mg/daily to glatiramer acetate 40 mg three times a week on gray and white matter pathology in subjects with relapsing multiple sclerosis: A longitudinal DTI study.

J Neurol Sci 2018 04 10;387:152-156. Epub 2018 Feb 10.

Jacobs Comprehensive MS Treatment and Research Center, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA; Department of Neurology, University of Buffalo, Buffalo, NY, USA.

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http://dx.doi.org/10.1016/j.jns.2018.02.023DOI Listing
April 2018

Multiple sclerosis: Extracranial venous angioplasty is ineffective to treat MS.

Nat Rev Neurol 2018 Mar 5;14(3):129-130. Epub 2018 Jan 5.

Jacobs Multiple Sclerosis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, 100 High Street, Buffalo, New York 14203, USA.

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http://dx.doi.org/10.1038/nrneurol.2017.180DOI Listing
March 2018

Trait neuroticism, extraversion, and conscientiousness in multiple sclerosis: Link to cognitive impairment?

Mult Scler 2018 02 1;24(2):205-213. Epub 2017 Feb 1.

Department of Neurology, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York (SUNY), Buffalo, NY, USA/Department of Neurology, Buffalo General Hospital, Buffalo, NY, USA.

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http://dx.doi.org/10.1177/1352458517695467DOI Listing
February 2018

Mapping of thalamic magnetic susceptibility in multiple sclerosis indicates decreasing iron with disease duration: A proposed mechanistic relationship between inflammation and oligodendrocyte vitality.

Neuroimage 2018 02 31;167:438-452. Epub 2017 Oct 31.

Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York, Buffalo, NY, USA; Center for Biomedical Imaging, Clinical and Translational Science Institute, University at Buffalo, The State University of New York, Buffalo, NY, USA.

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http://dx.doi.org/10.1016/j.neuroimage.2017.10.063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845810PMC
February 2018

Neck Vessel Cross-Sectional Area Measured with MRI: Scan-Rescan Reproducibility for Longitudinal Evaluations.

J Neuroimaging 2018 01 4;28(1):48-56. Epub 2017 Dec 4.

Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY.

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http://dx.doi.org/10.1111/jon.12488DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760334PMC
January 2018

Longitudinal personality change associated with cognitive decline in multiple sclerosis.

Mult Scler 2018 Jan 1:1352458517753720. Epub 2018 Jan 1.

Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York (SUNY), Buffalo, NY, USA.

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http://dx.doi.org/10.1177/1352458517753720DOI Listing
January 2018

Methods for the computation of templates from quantitative magnetic susceptibility maps (QSM): Toward improved atlas- and voxel-based analyses (VBA).

J Magn Reson Imaging 2017 11 6;46(5):1474-1484. Epub 2017 Mar 6.

Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York, USA.

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http://dx.doi.org/10.1002/jmri.25671DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587351PMC
November 2017

A Novel Semiautomated Pipeline to Measure Brain Atrophy and Lesion Burden in Multiple Sclerosis: A Long-Term Comparative Study.

J Neuroimaging 2017 11 2;27(6):620-629. Epub 2017 May 2.

Department of Neurology, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY.

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http://dx.doi.org/10.1111/jon.12445DOI Listing
November 2017

Leptomeningeal contrast enhancement is associated with progression of cortical atrophy in MS: A retrospective, pilot, observational longitudinal study.

Mult Scler 2017 Sep 4;23(10):1336-1345. Epub 2016 Nov 4.

Jacobs Multiple Sclerosis Center, Department of Neurology, School of Medicine and Biomedical Sciences, University at Buffalo-The State University of New York, Buffalo, NY, USA.

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http://dx.doi.org/10.1177/1352458516678083DOI Listing
September 2017

Differential effects of aging on motor and cognitive functioning in multiple sclerosis.

Mult Scler 2017 Sep 25;23(10):1385-1393. Epub 2016 Nov 25.

Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo-The State University of New York (SUNY), Buffalo, NY, USA/Department of Neurology, Buffalo General Hospital, Buffalo, NY, USA.

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http://dx.doi.org/10.1177/1352458516679036DOI Listing
September 2017

Ocrelizumab: a B-cell depleting therapy for multiple sclerosis.

Expert Opin Biol Ther 2017 09 3;17(9):1163-1172. Epub 2017 Jul 3.

a Buffalo Neuroimaging Analysis Center, Department of Neurology , Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York , Buffalo , NY , USA.

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http://dx.doi.org/10.1080/14712598.2017.1347632DOI Listing
September 2017

Olfactory identification deficit predicts white matter tract impairment in Alzheimer's disease.

Psychiatry Res Neuroimaging 2017 Aug 9;266:90-95. Epub 2017 Jun 9.

Alzheimer's Disease and Memory Disorder Center, Department of Neurology, University at Buffalo, SUNY, Buffalo, NY, United States. Electronic address:

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http://dx.doi.org/10.1016/j.pscychresns.2017.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973809PMC
August 2017

An improved FSL-FIRST pipeline for subcortical gray matter segmentation to study abnormal brain anatomy using quantitative susceptibility mapping (QSM).

Magn Reson Imaging 2017 06 7;39:110-122. Epub 2017 Feb 7.

Buffalo Neuroimaging Analysis Center, Dept. of Neurology, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY, United States; MRI Molecular and Translational Imaging Center, Buffalo CTRC, State University of New York at Buffalo, Buffalo, NY, United States.

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http://dx.doi.org/10.1016/j.mri.2017.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421359PMC
June 2017

Interdependence of oxysterols with cholesterol profiles in multiple sclerosis.

Mult Scler 2017 05 28;23(6):792-801. Epub 2016 Sep 28.

Department of Pharmaceutical Sciences, The State University of New York at Buffalo, Buffalo, NY, USA/Buffalo Neuroimaging Analysis Center, Department of Neurology, The State University of New York at Buffalo, Buffalo, NY, USA.

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http://dx.doi.org/10.1177/1352458516666187DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581166PMC
May 2017

An Observational Study to Assess Brain MRI Change and Disease Progression in Multiple Sclerosis Clinical Practice-The MS-MRIUS Study.

J Neuroimaging 2017 05 5;27(3):339-347. Epub 2016 Dec 5.

Jacobs Multiple Sclerosis Center, Department of Neurology, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY.

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http://dx.doi.org/10.1111/jon.12411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434824PMC
May 2017

Transcatheter aortic valve replacement: perioperative stroke and beyond.

Expert Rev Neurother 2017 04 7;17(4):327-334. Epub 2016 Nov 7.

d Departments of Neurosurgery and Radiology, Jacobs School of Medicine and Biomedical Sciences , University at Buffalo, State University of New York , Buffalo , NY , USA.

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http://dx.doi.org/10.1080/14737175.2017.1253475DOI Listing
April 2017

Synergistic Effects of Reserve and Adaptive Personality in Multiple Sclerosis.

J Int Neuropsychol Soc 2016 10 6;22(9):920-927. Epub 2016 May 6.

1Department of Neurology,School of Medicine and Biomedical Sciences,University at Buffalo,State University of New York (SUNY),Buffalo,New York.

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http://dx.doi.org/10.1017/S1355617716000333DOI Listing
October 2016