Publications by authors named "Robert Zeiser"

99Publications

Ruxolitinib-ECP combination treatment for refractory severe chronic graft-versus-host disease.

Bone Marrow Transplant 2020 Nov 17. Epub 2020 Nov 17.

Department of Medicine I, Faculty of Medicine, Medical Center-University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1038/s41409-020-01122-8DOI Listing
November 2020

Immune modulatory effects of oncogenic KRAS in cancer.

Nat Commun 2020 10 28;11(1):5439. Epub 2020 Oct 28.

Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1038/s41467-020-19288-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595113PMC
October 2020

Novel Biomarkers for Outcome After Allogeneic Hematopoietic Stem Cell Transplantation.

Front Immunol 2020 18;11:1854. Epub 2020 Aug 18.

Department of Medicine I, Faculty of Medicine, Medical Center, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.3389/fimmu.2020.01854DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461883PMC
August 2020

The development of ruxolitinib for glucocorticoid-refractory acute graft-versus-host disease.

Blood Adv 2020 Aug;4(15):3789-3794

Hematology-Transplantation, Hospital St. Louis, Assistance Publique-Hôpitaux de Paris, Paris, France.

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http://dx.doi.org/10.1182/bloodadvances.2020002097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7422131PMC
August 2020

Refractory acute graft-versus-host disease: a new working definition beyond corticosteroid refractoriness.

Blood 2020 Oct;136(17):1903-1906

Department of Medicine I, Faculty of Medicine, Medical Center, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1182/blood.2020007336DOI Listing
October 2020

NLRP3 Inflammasome Activation in Cancer: A Double-Edged Sword.

Front Immunol 2020 8;11:1444. Epub 2020 Jul 8.

Department of Medicine I, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.3389/fimmu.2020.01444DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360837PMC
July 2020

Ruxolitinib for Acute Graft-versus-Host Disease. Reply.

N Engl J Med 2020 07;383(5)

Hôpital St. Louis, Paris, France.

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http://dx.doi.org/10.1056/NEJMc2020763DOI Listing
July 2020

Immunotherapy in Myeloproliferative Diseases.

Cells 2020 06 26;9(6). Epub 2020 Jun 26.

Department of Medicine I, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.

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http://dx.doi.org/10.3390/cells9061559DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349594PMC
June 2020

Introduction to a review series on pathophysiology and treatment of acute GVHD.

Authors:
Robert Zeiser

Blood 2020 Jul;136(4):375-376

Associate Editor, Blood.

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http://dx.doi.org/10.1182/blood.2019004271DOI Listing
July 2020

Trigger-dependent differences determine therapeutic outcome in murine primary hemophagocytic lymphohistiocytosis.

Eur J Immunol 2020 Nov 2;50(11):1770-1782. Epub 2020 Jun 2.

Center for Chronic Immunodeficiency (CCI), Faculty of Medicine, Institute for Immunodeficiency, Medical Center, University of Freiburg, Germany.

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http://dx.doi.org/10.1002/eji.201948123DOI Listing
November 2020

Ruxolitinib for Glucocorticoid-Refractory Acute Graft-versus-Host Disease.

N Engl J Med 2020 05 22;382(19):1800-1810. Epub 2020 Apr 22.

From the Department of Medicine I, Faculty of Medicine, Medical Center, University of Freiburg, Freiburg (R.Z.), the Department of Hematology and Oncology, University Hospital Schleswig-Holstein, Campus Lübeck, Lübeck (N.B.), the Department of Hematology and Oncology, University of Leipzig, Leipzig (D.N.), and the Department of Hematology, Oncology, and Pneumology, University Medical Center Mainz, Mainz (E.M.W.) - all in Germany; the Department of Bone Marrow Transplantation, Royal Brisbane and Women's Hospital, Brisbane, QLD (J.B.), and the Peter MacCallum Cancer Centre and Royal Melbourne Hospital, Melbourne, VIC (J.S.) - all in Australia; Hôpital Saint-Antoine, Assistance Publique-Hôpitaux de Paris (AP-HP), Université Sorbonne and INSERM Unité Mixte de Recherche (UMR) 938 (M.M.), and AP-HP, Hématologie-Transplantation, Hôpital St. Louis, Université de Paris and INSERM UMR 976 (G.S.), Paris, and Novartis Pharma, Rueil-Malmaison (B.M.) - all in France; the Cancer Immunotherapy and Immunobiology Research Center, Hadassah University Hospital, Jerusalem (R.O.), and the Hematology Institute and Bone Marrow Transplantation, Clinical Research Institute at Rambam, Rambam Health Care Campus, Haifa (T.Z.) - both in Israel; Novartis Pharmaceuticals, East Hanover, NJ (J.X., K.K.G.); and Novartis Pharma, Basel, Switzerland (C.W.).

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http://dx.doi.org/10.1056/NEJMoa1917635DOI Listing
May 2020

Introduction to a How I Treat series on major complications after allogeneic stem cell transplantation.

Authors:
Robert Zeiser

Blood 2020 May;135(19):1609

Associate Editor, Blood.

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http://dx.doi.org/10.1182/blood.2020005811DOI Listing
May 2020

Clinicians and patients perspectives on follow-up care and eHealth support after allogeneic hematopoietic stem cell transplantation: A mixed-methods contextual analysis as part of the SMILe study.

Eur J Oncol Nurs 2020 Apr 22;45:101723. Epub 2020 Jan 22.

Institute of Nursing Science, Department Public Health, University of Basel, Switzerland; Academic Centre for Nursing and Midwifery, Department of Public Health and Primary Care, KU Leuven, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.ejon.2020.101723DOI Listing
April 2020

Extracorporeal Photopheresis for Colitis Induced by Checkpoint-Inhibitor Therapy.

N Engl J Med 2020 01;382(3):294-296

University Medical Center Freiburg, Freiburg, Germany

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http://dx.doi.org/10.1056/NEJMc1912274DOI Listing
January 2020

Advances in understanding the pathogenesis of graft-versus-host disease.

Authors:
Robert Zeiser

Br J Haematol 2019 12 6;187(5):563-572. Epub 2019 Oct 6.

Department of Haematology, Oncology and Stem Cell Transplantation, Faculty of Medicine, Freiburg University Medical Centre, Freiburg, Germany.

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http://dx.doi.org/10.1111/bjh.16190DOI Listing
December 2019

MHC Class II Antigen Presentation by the Intestinal Epithelium Initiates Graft-versus-Host Disease and Is Influenced by the Microbiota.

Immunity 2019 11 18;51(5):885-898.e7. Epub 2019 Sep 18.

Bone Marrow Transplantation Laboratory, Immunology Department, QIMR Berghofer Medical Research Institute, Brisbane, QLD 4006, Australia; Department of Haematology and Bone Marrow Transplantation, Cancer Care Services, Royal Brisbane and Women's Hospital, Brisbane, QLD 4029, Australia; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Division of Medical Oncology, University of Washington, Seattle, WA 98109, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2019.08.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959419PMC
November 2019

SNAIL1 employs β-Catenin-LEF1 complexes to control colorectal cancer cell invasion and proliferation.

Int J Cancer 2020 04 18;146(8):2229-2242. Epub 2019 Sep 18.

Institute of Molecular Medicine and Cell Research, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1002/ijc.32644DOI Listing
April 2020

Clinical implications of tumor-intrinsic mechanisms regulating PD-L1.

Sci Transl Med 2019 02;11(478)

Department of Hematology and Oncology, Freiburg University Medical Center, 79106 Freiburg, Germany.

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http://stm.sciencemag.org/lookup/doi/10.1126/scitranslmed.aa
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http://dx.doi.org/10.1126/scitranslmed.aav4810DOI Listing
February 2019

Intestinal Microbiota Influence Immune Tolerance Post Allogeneic Hematopoietic Cell Transplantation and Intestinal GVHD.

Front Immunol 2018 17;9:3179. Epub 2019 Jan 17.

Department of Hematology, Oncology and Stem Cell Transplantation, Faculty of Medicine, University Medical Center, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.3389/fimmu.2018.03179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344415PMC
October 2019

High-dimensional single-cell proteomics analysis identifies immune checkpoint signatures and therapeutic targets in ulcerative colitis.

Eur J Immunol 2019 03 9;49(3):462-475. Epub 2019 Jan 9.

Roche Pharma Research and Early Development, Immunology, Inflammation and Infectious Diseases (I3) Discovery and Translational Area, Roche Innovation Center Basel, Basel, Switzerland.

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http://doi.wiley.com/10.1002/eji.201847862
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http://dx.doi.org/10.1002/eji.201847862DOI Listing
March 2019

Mechanisms of immune escape after allogeneic hematopoietic cell transplantation.

Blood 2019 03 21;133(12):1290-1297. Epub 2018 Dec 21.

Unit of Immunogenetics, Leukemia Genomics, and Immunobiology and.

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http://www.bloodjournal.org/lookup/doi/10.1182/blood-2018-10
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http://dx.doi.org/10.1182/blood-2018-10-846824DOI Listing
March 2019

Editorial: Non-coding RNAs and Graft versus Host Disease.

Front Immunol 2018 20;9:2713. Epub 2018 Nov 20.

Department of Hematology, Oncology and Stem Cell Transplantation, Freiburg University Medical Center, Albert Ludwigs University of Freiburg, Freiburg, Germany.

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https://www.frontiersin.org/article/10.3389/fimmu.2018.02713
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http://dx.doi.org/10.3389/fimmu.2018.02713DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256834PMC
October 2019

Biology-driven developments in the therapy of acute graft-versus-host disease.

Authors:
Robert Zeiser

Hematology Am Soc Hematol Educ Program 2018 11;2018(1):236-241

Department of Hematology, Oncology and Stem Cell Transplantation, Faculty of Medicine, Freiburg University Medical Center, Freiburg, Germany.

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http://dx.doi.org/10.1182/asheducation-2018.1.236DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245989PMC
November 2018

Cobimetinib (GDC-0973, XL518).

Recent Results Cancer Res 2018;211:177-186

Department of Dermatology and Venereology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Hauptstr. 7, 79104, Freiburg, Germany.

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http://dx.doi.org/10.1007/978-3-319-91442-8_12DOI Listing
November 2018

Vismodegib.

Recent Results Cancer Res 2018;211:125-139

Department of Hematology, Oncology and Stem Cell Transplantation, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany.

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http://dx.doi.org/10.1007/978-3-319-91442-8_9DOI Listing
November 2018

Trametinib (GSK1120212).

Recent Results Cancer Res 2018;211:91-100

Department of Dermatology and Venereology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Hauptstr. 7, 79104, Freiburg, Germany.

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http://dx.doi.org/10.1007/978-3-319-91442-8_7DOI Listing
November 2018

Ruxolitinib.

Recent Results Cancer Res 2018;212:119-132

Department of Hematology and Oncology, University of Freiburg Medical Center, Hugstetter Str. 55, 79106, Freiburg, Germany.

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http://dx.doi.org/10.1007/978-3-319-91439-8_6DOI Listing
May 2019

Decitabine in combination with donor lymphocyte infusions can induce remissions in relapsed myeloid malignancies with higher leukemic burden after allogeneic hematopoietic cell transplantation.

Leuk Res 2018 09 7;72:20-26. Epub 2018 Jul 7.

Department of Hematology, Oncology and Stem Cell Transplantation, University of Freiburg Medical Center, Freiburg, Germany; German Cancer Consortium (DKTK), Freiburg, Germany; German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2018.07.005DOI Listing
September 2018

P2Y2R Signaling Is Involved in the Onset of Glomerulonephritis.

Front Immunol 2018 16;9:1589. Epub 2018 Jul 16.

Department of Medicine IV, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.3389/fimmu.2018.01589DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054981PMC
July 2018

Impact of Lung Function on Bronchiolitis Obliterans Syndrome and Outcome after Allogeneic Hematopoietic Cell Transplantation with Reduced-Intensity Conditioning.

Biol Blood Marrow Transplant 2018 11 28;24(11):2277-2284. Epub 2018 Jun 28.

Department of Pneumology, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany; Department of Pneumology, University of Hannover, Hannover, Germany.

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http://dx.doi.org/10.1016/j.bbmt.2018.06.024DOI Listing
November 2018

Erratum: Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells.

Authors:
Nimitha R Mathew Francis Baumgartner Lukas Braun David O'Sullivan Simone Thomas Miguel Waterhouse Tony A Müller Kathrin Hanke Sanaz Taromi Petya Apostolova Anna L Illert Wolfgang Melchinger Sandra Duquesne Annette Schmitt-Graeff Lena Osswald Kai-Li Yan Arnim Weber Sonia Tugues Sabine Spath Dietmar Pfeifer Marie Follo Rainer Claus Michael Lübbert Christoph Rummelt Hartmut Bertz Ralph Wäsch Johanna Haag Andrea Schmidts Michael Schultheiss Dominik Bettinger Robert Thimme Evelyn Ullrich Yakup Tanriver Giang Lam Vuong Renate Arnold Philipp Hemmati Dominik Wolf Markus Ditschkowski Cordula Jilg Konrad Wilhelm Christian Leiber Sabine Gerull Jörg Halter Claudia Lengerke Thomas Pabst Thomas Schroeder Guido Kobbe Wolf Rösler Soroush Doostkam Stephan Meckel Kathleen Stabla Stephan K Metzelder Sebastian Halbach Tilman Brummer Zehan Hu Joern Dengjel Björn Hackanson Christoph Schmid Udo Holtick Christof Scheid Alexandros Spyridonidis Friedrich Stölzel Rainer Ordemann Lutz P Müller Flore Sicre-de-Fontbrune Gabriele Ihorst Jürgen Kuball Jan E Ehlert Daniel Feger Eva-Maria Wagner Jean-Yves Cahn Jacqueline Schnell Florian Kuchenbauer Donald Bunjes Ronjon Chakraverty Simon Richardson Saar Gill Nicolaus Kröger Francis Ayuk Luca Vago Fabio Ciceri Antonia M Müller Takeshi Kondo Takanori Teshima Susan Klaeger Bernhard Kuster Dennis Dong Hwan Kim Daniel Weisdorf Walter van der Velden Daniela Dörfel Wolfgang Bethge Inken Hilgendorf Andreas Hochhaus Geoffroy Andrieux Melanie Börries Hauke Busch John Magenau Pavan Reddy Myriam Labopin Joseph H Antin Andrea S Henden Geoffrey R Hill Glen A Kennedy Merav Bar Anita Sarma Donal McLornan Ghulam Mufti Betul Oran Katayoun Rezvani Omid Shah Robert S Negrin Arnon Nagler Marco Prinz Andreas Burchert Andreas Neubauer Dietrich Beelen Andreas Mackensen Nikolas von Bubnoff Wolfgang Herr Burkhard Becher Gerard Socié Michael A Caligiuri Eliana Ruggiero Chiara Bonini Georg Häcker Justus Duyster Jürgen Finke Erika Pearce Bruce R Blazar Robert Zeiser

Nat Med 2018 Apr;24(4):526

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http://dx.doi.org/10.1038/nm0418-526cDOI Listing
April 2018

Detection of major histocompatibility complex molecules in processed allogeneic bone blocks for use in alveolar ridge reconstruction.

Oral Surg Oral Med Oral Pathol Oral Radiol 2018 Mar 20. Epub 2018 Mar 20.

Department of Oral and Craniomaxillofacial Surgery, Medical Center, University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S22124403183005
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http://dx.doi.org/10.1016/j.oooo.2018.01.018DOI Listing
March 2018

B-cell targeting in chronic graft-versus-host disease.

Blood 2018 03 1;131(13):1399-1405. Epub 2018 Feb 1.

Division of Blood and Marrow Transplantation, Department of Pediatrics, University of Minnesota, Minneapolis, MN.

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http://dx.doi.org/10.1182/blood-2017-11-784017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031308PMC
March 2018

Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells.

Authors:
Nimitha R Mathew Francis Baumgartner Lukas Braun David O'Sullivan Simone Thomas Miguel Waterhouse Tony A Müller Kathrin Hanke Sanaz Taromi Petya Apostolova Anna L Illert Wolfgang Melchinger Sandra Duquesne Annette Schmitt-Graeff Lena Osswald Kai-Li Yan Arnim Weber Sonia Tugues Sabine Spath Dietmar Pfeifer Marie Follo Rainer Claus Michael Lübbert Christoph Rummelt Hartmut Bertz Ralph Wäsch Johanna Haag Andrea Schmidts Michael Schultheiss Dominik Bettinger Robert Thimme Evelyn Ullrich Yakup Tanriver Giang Lam Vuong Renate Arnold Philipp Hemmati Dominik Wolf Markus Ditschkowski Cordula Jilg Konrad Wilhelm Christian Leiber Sabine Gerull Jörg Halter Claudia Lengerke Thomas Pabst Thomas Schroeder Guido Kobbe Wolf Rösler Soroush Doostkam Stephan Meckel Kathleen Stabla Stephan K Metzelder Sebastian Halbach Tilman Brummer Zehan Hu Joern Dengjel Björn Hackanson Christoph Schmid Udo Holtick Christof Scheid Alexandros Spyridonidis Friedrich Stölzel Rainer Ordemann Lutz P Müller Flore Sicre-de-Fontbrune Gabriele Ihorst Jürgen Kuball Jan E Ehlert Daniel Feger Eva-Maria Wagner Jean-Yves Cahn Jacqueline Schnell Florian Kuchenbauer Donald Bunjes Ronjon Chakraverty Simon Richardson Saar Gill Nicolaus Kröger Francis Ayuk Luca Vago Fabio Ciceri Antonia M Müller Takeshi Kondo Takanori Teshima Susan Klaeger Bernhard Kuster Dennis Dong Hwan Kim Daniel Weisdorf Walter van der Velden Daniela Dörfel Wolfgang Bethge Inken Hilgendorf Andreas Hochhaus Geoffroy Andrieux Melanie Börries Hauke Busch John Magenau Pavan Reddy Myriam Labopin Joseph H Antin Andrea S Henden Geoffrey R Hill Glen A Kennedy Merav Bar Anita Sarma Donal McLornan Ghulam Mufti Betul Oran Katayoun Rezvani Omid Shah Robert S Negrin Arnon Nagler Marco Prinz Andreas Burchert Andreas Neubauer Dietrich Beelen Andreas Mackensen Nikolas von Bubnoff Wolfgang Herr Burkhard Becher Gerard Socié Michael A Caligiuri Eliana Ruggiero Chiara Bonini Georg Häcker Justus Duyster Jürgen Finke Erika Pearce Bruce R Blazar Robert Zeiser

Nat Med 2018 03 12;24(3):282-291. Epub 2018 Feb 12.

Department of Hematology, Oncology and Stem Cell Transplantation, Faculty of Medicine, University Medical Center Freiburg, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1038/nm.4484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029618PMC
March 2018

Acute Graft-versus-Host Disease.

N Engl J Med 2018 02;378(6):586

University of Minnesota, Minneapolis, MN

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http://dx.doi.org/10.1056/NEJMc1716969DOI Listing
February 2018

The Role of MicroRNAs in Myeloid Cells during Graft-versus-Host Disease.

Front Immunol 2018 23;9. Epub 2018 Jan 23.

Department of Hematology, Oncology and Stem Cell Transplantation, Freiburg University Medical Center, Freiburg, Germany.

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http://dx.doi.org/10.3389/fimmu.2018.00004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787138PMC
February 2019

Immune modulatory effects of statins.

Authors:
Robert Zeiser

Immunology 2018 05 20;154(1):69-75. Epub 2018 Feb 20.

Department of Haematology, Oncology and Stem Cell Transplantation, Freiburg University Medical Centre, Freiburg, Germany.

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http://dx.doi.org/10.1111/imm.12902DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904709PMC
May 2018

Introduction to a review series on strategies to improve GVL effects.

Authors:
Robert Zeiser

Blood 2018 03 22;131(10):1039. Epub 2018 Jan 22.

Associate Editor, Blood.

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http://dx.doi.org/10.1182/blood-2017-11-814467DOI Listing
March 2018

Ruxolitinib for the treatment of patients with steroid-refractory GVHD: an introduction to the REACH  trials.

Immunotherapy 2018 04 10;10(5):391-402. Epub 2018 Jan 10.

Department of Hematology, Oncology & Stem Cell Transplantation, University Hospital Freiburg, Hugstetter Str. 55, 79106 Freiburg im Breisgau, Germany.

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https://www.futuremedicine.com/doi/10.2217/imt-2017-0156
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http://dx.doi.org/10.2217/imt-2017-0156DOI Listing
April 2018

Pathophysiology of Chronic Graft-versus-Host Disease and Therapeutic Targets.

N Engl J Med 2017 12;377(26):2565-2579

From the Department of Hematology, Oncology, and Stem Cell Transplantation, Faculty of Medicine, Freiburg University, Freiburg, Germany (R.Z.); and the Department of Pediatrics, Division of Blood and Marrow Transplantation, University of Minnesota, Minneapolis (B.R.B.).

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http://dx.doi.org/10.1056/NEJMra1703472DOI Listing
December 2017

Negative regulation of TGF-β1-induced MKK6-p38 and MEK-ERK signalling and epithelial-mesenchymal transition by Rac1b.

Sci Rep 2017 12 11;7(1):17313. Epub 2017 Dec 11.

First Department of Medicine, University Hospital Schleswig-Holstein (UKSH), Campus Lübeck, and University of Lübeck, 23538, Lübeck, Germany.

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http://www.nature.com/articles/s41598-017-15170-6
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http://dx.doi.org/10.1038/s41598-017-15170-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725500PMC
December 2017

MicroRNA-100 Suppresses Chronic Vascular Inflammation by Stimulation of Endothelial Autophagy.

Circ Res 2018 02 5;122(3):417-432. Epub 2017 Dec 5.

From the Department of Cardiology and Angiology I, Heart Center Freiburg University, Faculty of Medicine, University of Freiburg, Germany (F.P., C.H., X.B., C.J., S.K., C.S., L.S., J.M., M.J., T.H., M.M., C.B., S.G.); Laboratory of Clinical Chemistry and Haematology, University Medical Center Utrecht, The Netherlands (I.H., G.P.); and Department of Hematology, Oncology, and Stem Cell Transplantation, Medical Center, Faculty of Medicine, University of Freiburg, Germany (J.M., R.Z.).

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http://dx.doi.org/10.1161/CIRCRESAHA.117.311428DOI Listing
February 2018

Acute Graft-versus-Host Disease - Biologic Process, Prevention, and Therapy.

N Engl J Med 2017 11;377(22):2167-2179

From the Department of Hematology, Oncology, and Stem Cell Transplantation, Faculty of Medicine, Freiburg University Medical Center, Freiburg, Germany (R.Z.); and the Department of Pediatrics, Division of Blood and Marrow Transplantation, University of Minnesota, Minneapolis (B.R.B.).

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http://dx.doi.org/10.1056/NEJMra1609337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034180PMC
November 2017

The Atypical Kinase RIOK1 Promotes Tumor Growth and Invasive Behavior.

EBioMedicine 2017 Jun 12;20:79-97. Epub 2017 Apr 12.

Institute of Molecular Medicine and Cell Research (IMMZ), Faculty of Medicine, Albert-Ludwigs-University (ALU), Freiburg, Germany; Faculty of Biology, ALU, Freiburg, Germany; BIOSS Centre for Biological Signalling Studies, BIOSS, ALU, Germany; German Cancer Consortium (DKTK, Freiburg) and German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2017.04.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478185PMC
June 2017

Pregnancy Specific β-1 Glycoprotein 1 is Expressed in Pancreatic Ductal Adenocarcinoma and its Subcellular Localization Correlates with Overall Survival.

J Cancer 2016 17;7(14):2018-2027. Epub 2016 Oct 17.

Institute of Molecular Medicine and Cell Research, University of Freiburg, Germany;; BIOSS Centre for Biological Signaling Studies, University of Freiburg, D-79104 Freiburg, Germany;; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, German.

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http://dx.doi.org/10.7150/jca.15864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118665PMC
October 2016

CXCR4 antagonists suppress small cell lung cancer progression.

Oncotarget 2016 Dec;7(51):85185-85195

Department of Medicine, Division of Hematology/Oncology, University Medical Center, Hugstetter, D-79106 Freiburg, Germany.

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http://dx.doi.org/10.18632/oncotarget.13238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356728PMC
December 2016

The Role of Purine Metabolites as DAMPs in Acute Graft-versus-Host Disease.

Front Immunol 2016 21;7:439. Epub 2016 Oct 21.

Department of Hematology, Oncology and Stem Cell Transplantation, University Medical Center, Albert Ludwig University of Freiburg , Freiburg , Germany.

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http://dx.doi.org/10.3389/fimmu.2016.00439DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073102PMC
October 2016

Pathogenesis of acute graft-versus-host disease: from intestinal microbiota alterations to donor T cell activation.

Br J Haematol 2016 Oct 13;175(2):191-207. Epub 2016 Sep 13.

Department of Pediatrics, Division of Blood and Marrow Transplantation, University of Minnesota, Minneapolis, MN, USA.

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http://dx.doi.org/10.1111/bjh.14295DOI Listing
October 2016

Matching for the nonconventional MHC-I MICA gene significantly reduces the incidence of acute and chronic GVHD.

Blood 2016 10 22;128(15):1979-1986. Epub 2016 Aug 22.

Laboratoire d'ImmunoRhumatologie Moléculaire, INSERM Unité Mixte de Recherche (UMR)_S1109, Plateforme GENOMAX, Faculté de Médecine, Fédération Hospitalo-Universitaire OMICARE, Fédération de Médecine Translationnelle de Strasbourg, and LabEx TRANSPLANTEX, Faculté de Médecine, Université de Strasbourg, Strasbourg, France; INSERM Franco-Japanese Nextgen HLA laboratory, Nagano, Japan and Strasbourg, France; Laboratoire d'Immunologie, Plateau Technique de Biologie, Pôle de Biologie, Nouvel Hôpital Civil, Strasbourg, France.

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http://dx.doi.org/10.1182/blood-2016-05-719070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147017PMC
October 2016

Loss of LSR affects epithelial barrier integrity and tumor xenograft growth of CaCo-2 cells.

Oncotarget 2017 Jun;8(23):37009-37022

Institute of Experimental and Clinical Pharmacology and Toxicology, Albert-Ludwigs-University (ALU), Freiburg, Germany.

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http://dx.doi.org/10.18632/oncotarget.10425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514888PMC
June 2017

An orthotopic mouse model of small cell lung cancer reflects the clinical course in patients.

Clin Exp Metastasis 2016 10 6;33(7):651-60. Epub 2016 Jul 6.

Department of Hematology/Oncology and Stem Cell Transplantation, University Medical Center, Hugstetter Str. 55, 70106, Freiburg, Germany.

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http://dx.doi.org/10.1007/s10585-016-9808-8DOI Listing
October 2016

In Vivo Myeloperoxidase Imaging and Flow Cytometry Analysis of Intestinal Myeloid Cells.

Methods Mol Biol 2016 ;1422:161-7

Department of Hematology, Oncology and Stem Cell Transplantation, Freiburg University Medical Center, Albert Ludwigs University Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1007/978-1-4939-3603-8_15DOI Listing
December 2017