Robert Yarchoan

Robert Yarchoan

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Robert Yarchoan

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Induction of Kaposi's Sarcoma-Associated Herpesvirus-Encoded Thymidine Kinase (ORF21) by X-Box Binding Protein 1.

J Virol 2020 Feb 14;94(5). Epub 2020 Feb 14.

HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA

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http://dx.doi.org/10.1128/JVI.01555-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022350PMC
February 2020

Signatures of oral microbiome in HIV-infected individuals with oral Kaposi's sarcoma and cell-associated KSHV DNA.

PLoS Pathog 2020 01 17;16(1):e1008114. Epub 2020 Jan 17.

Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1008114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992226PMC
January 2020

The Changing Face of HIV-Associated Malignancies: Advances, Opportunities, and Future Directions.

Am Soc Clin Oncol Educ Book 2019 Jan 17;39:36-40. Epub 2019 May 17.

1 HIV & AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD.

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http://dx.doi.org/10.1200/EDBK_100017DOI Listing
January 2019

Discovery of Kaposi's sarcoma herpesvirus-encoded circular RNAs and a human antiviral circular RNA.

Proc Natl Acad Sci U S A 2018 12 19;115(50):12805-12810. Epub 2018 Nov 19.

HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892;

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http://dx.doi.org/10.1073/pnas.1816183115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294913PMC
December 2018

Relationship Between Anemia, Malaria Coinfection, and Kaposi Sarcoma-Associated Herpesvirus Seropositivity in a Population-Based Study in Rural Uganda.

J Infect Dis 2018 08;218(7):1061-1065

Medical Research Council/Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine Uganda Research Unit, Entebbe, Uganda.

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http://dx.doi.org/10.1093/infdis/jiy274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107741PMC
August 2018

HIV-Associated Cancers and Related Diseases.

N Engl J Med 2018 05;378(22):2145

Fred Hutchinson Cancer Research Center, Seattle, WA

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http://dx.doi.org/10.1056/NEJMc1804812DOI Listing
May 2018

HIV-Associated Cancers and Related Diseases.

N Engl J Med 2018 Mar;378(11):1029-1041

From the HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD.

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http://dx.doi.org/10.1056/NEJMra1615896DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890231PMC
March 2018

Treatment of Kaposi Sarcoma Herpesvirus-Associated Multicentric Castleman Disease.

Hematol Oncol Clin North Am 2018 02;32(1):75-88

HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, 10 Center Drive, Bethesda, MD 20892-1868, USA. Electronic address:

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http://dx.doi.org/10.1016/j.hoc.2017.09.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726416PMC
February 2018

Evidence for a Mesothelial Origin of Body Cavity Effusion Lymphomas.

J Natl Cancer Inst 2017 09;109(9)

Laboratory of Cellular Oncology, Center for Cancer Research, National Cancer Institute, National Institutes of Health (NIH), Bethesda, MD, USA.

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http://dx.doi.org/10.1093/jnci/djx016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059237PMC
September 2017

HIV-associated Kaposi sarcoma and related diseases.

AIDS 2017 09;31(14):1903-1916

HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1097/QAD.0000000000001567DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310482PMC
September 2017

Hypoxia-inducible factor-1 alpha as a therapeutic target for primary effusion lymphoma.

PLoS Pathog 2017 Sep 18;13(9):e1006628. Epub 2017 Sep 18.

HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1006628DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619862PMC
September 2017

Identification of functional hypoxia inducible factor response elements in the human lysyl oxidase gene promoter.

Biochem Biophys Res Commun 2017 08 15;490(2):480-485. Epub 2017 Jun 15.

HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2017.06.066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309311PMC
August 2017

Corrigendum: Clinical manifestations of Kaposi sarcoma herpesvirus lytic activation: multicentric Castleman disease (KSHV-MCD) and the KSHV inflammatory cytokine syndrome.

Front Microbiol 2017 21;8:1572. Epub 2017 Aug 21.

HIV/AIDS Malignancy Branch, Center for Cancer Research, National Cancer InstituteBethesda, MD, United States.

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http://dx.doi.org/10.3389/fmicb.2017.01572DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572060PMC
August 2017

Kaposi sarcoma herpesvirus-associated cancers and related diseases.

Curr Opin HIV AIDS 2017 01;12(1):47-56

HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1097/COH.0000000000000330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311702PMC
January 2017

RNA Sequencing Reveals that Kaposi Sarcoma-Associated Herpesvirus Infection Mimics Hypoxia Gene Expression Signature.

PLoS Pathog 2017 01 3;13(1):e1006143. Epub 2017 Jan 3.

HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1006143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234848PMC
January 2017

Pomalidomide for Symptomatic Kaposi's Sarcoma in People With and Without HIV Infection: A Phase I/II Study.

J Clin Oncol 2016 12 31;34(34):4125-4131. Epub 2016 Oct 31.

Mark N. Polizzotto, Thomas S. Uldrick, Kathleen M. Wyvill, Karen Aleman, Cody J. Peer, Frank Maldarelli, Priscila H. Goncalves, William D. Figg, Seth M. Steinberg, and Robert Yarchoan, National Cancer Institute; Margaret Bevans, National Institutes of Health; Irini Sereti, National Institute of Allergy and Infectious Diseases, Bethesda, MD; Denise Whitby and Vickie Marshall, Frederick National Cancer Laboratory for Cancer Research, Frederick, MD; and Vikram Khetani and Jerome B. Zeldis, Celgene Corporation, Summit, NJ.

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http://dx.doi.org/10.1200/JCO.2016.69.3812DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477825PMC
December 2016

Next-Generation Sequencing Analysis Reveals Differential Expression Profiles of MiRNA-mRNA Target Pairs in KSHV-Infected Cells.

PLoS One 2015 5;10(5):e0126439. Epub 2015 May 5.

HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0126439PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420468PMC
April 2016

Cancer prevention in HIV-infected populations.

Semin Oncol 2016 Feb 8;43(1):173-188. Epub 2015 Sep 8.

HIV & AIDS Malignancy Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. Electronic address:

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http://dx.doi.org/10.1053/j.seminoncol.2015.09.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789150PMC
February 2016

Induction of Kaposi's Sarcoma-Associated Herpesvirus-Encoded Viral Interleukin-6 by X-Box Binding Protein 1.

J Virol 2016 01 21;90(1):368-78. Epub 2015 Oct 21.

HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA

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http://dx.doi.org/10.1128/JVI.01192-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702535PMC
January 2016

Identification of Caspase Cleavage Sites in KSHV Latency-Associated Nuclear Antigen and Their Effects on Caspase-Related Host Defense Responses.

PLoS Pathog 2015 Jul 28;11(7):e1005064. Epub 2015 Jul 28.

HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1005064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517896PMC
July 2015

Kaposi sarcoma-associated herpesvirus-associated malignancies: epidemiology, pathogenesis, and advances in treatment.

Semin Oncol 2015 Apr 31;42(2):223-46. Epub 2014 Dec 31.

HIV and AIDS Malignancy Branch, Center for Cancer Research, NCI, Bethesda, MD. Electronic address:

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http://dx.doi.org/10.1053/j.seminoncol.2014.12.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309362PMC
April 2015

Evaluation of non-invasive multispectral imaging as a tool for measuring the effect of systemic therapy in Kaposi sarcoma.

PLoS One 2013 27;8(12):e83887. Epub 2013 Dec 27.

Section on Analytical and Functional Biophotonics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0083887PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873970PMC
August 2014

Heterogeneity and breadth of host antibody response to KSHV infection demonstrated by systematic analysis of the KSHV proteome.

PLoS Pathog 2014 Mar 27;10(3):e1004046. Epub 2014 Mar 27.

Viral Oncology Section, AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1004046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968157PMC
March 2014

Noninvasive Multimodality Imaging Techniques to Assess Kaposi's Sarcoma.

Conf Proc IEEE Eng Med Biol Soc 2005;2006:694-6

Lab. of Integrative and Medical Biophysics, National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), Bethesda, MD 20892, USA. Email:

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http://dx.doi.org/10.1109/IEMBS.2005.1616508DOI Listing
October 2012

Clinical Manifestations of Kaposi Sarcoma Herpesvirus Lytic Activation: Multicentric Castleman Disease (KSHV-MCD) and the KSHV Inflammatory Cytokine Syndrome.

Front Microbiol 2012 2;3:73. Epub 2012 Mar 2.

HIV/AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute Bethesda, MD, USA.

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http://dx.doi.org/10.3389/fmicb.2012.00073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291870PMC
October 2012

Recent advances in Kaposi sarcoma herpesvirus-associated multicentric Castleman disease.

Curr Opin Oncol 2012 Sep;24(5):495-505

HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1097/CCO.0b013e328355e0f3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322210PMC
September 2012

Lack of Detection of Xenotropic Murine Leukemia Virus-Related Virus in HIV-1 Lymphoma Patients.

Adv Virol 2011 8;2011:797820. Epub 2011 Sep 8.

Viral Mutation Section, HIV Drug Resistance Program, National Cancer Institute at Frederick, National Institutes of Health, Frederick, MD 21702, USA.

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http://dx.doi.org/10.1155/2011/797820DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265315PMC
August 2012

Activity of human immunodeficiency virus type 1 protease inhibitors against the initial autocleavage in Gag-Pol polyprotein processing.

Antimicrob Agents Chemother 2012 Jul 16;56(7):3620-8. Epub 2012 Apr 16.

HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland, USA.

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http://aac.asm.org/content/56/7/3620.full.pdf
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http://aac.asm.org/cgi/doi/10.1128/AAC.00055-12
Publisher Site
http://dx.doi.org/10.1128/AAC.00055-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393404PMC
July 2012

Sorafenib is an inhibitor of UGT1A1 but is metabolized by UGT1A9: implications of genetic variants on pharmacokinetics and hyperbilirubinemia.

Clin Cancer Res 2012 Apr 3;18(7):2099-107. Epub 2012 Feb 3.

Clinical Pharmacology Program, Pharmacology and Experimental Therapeutics Section, Molecular Pharmacology Section, Biostatistics and Data Management Branch, Medical Oncology Branch, and HIV/AIDS Malignancy Branch, National Cancer Institute, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-11-2484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6432766PMC
April 2012

Kaposi sarcoma herpesvirus promotes endothelial-to-mesenchymal transition through Notch-dependent signaling.

Cancer Res 2012 Mar 11;72(5):1157-69. Epub 2012 Jan 11.

Laboratory of Cellular Oncology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-3067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3512101PMC
March 2012

Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen induction by hypoxia and hypoxia-inducible factors.

J Virol 2012 Jan 16;86(2):1097-108. Epub 2011 Nov 16.

HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1128/JVI.05167-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255810PMC
January 2012

Kaposi's sarcoma-associated herpesviral IL-6 and human IL-6 open reading frames contain miRNA binding sites and are subject to cellular miRNA regulation.

J Pathol 2011 Nov 24;225(3):378-89. Epub 2011 Aug 24.

HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1002/path.2962DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528401PMC
November 2011

Population pharmacokinetic analysis of sorafenib in patients with solid tumours.

Br J Clin Pharmacol 2011 Aug;72(2):294-305

Clinical Pharmacology Program Medical Oncology Branch, National Cancer Institute, NIH, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1111/j.1365-2125.2011.03963.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162659PMC
August 2011

IL-15 ex vivo overcomes CD4+ T cell deficiency for the induction of human antigen-specific CD8+ T cell responses.

J Leukoc Biol 2011 Jul 7;90(1):205-14. Epub 2011 Apr 7.

Vaccine Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1189/jlb.1010579DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114597PMC
July 2011

Cancer burden in the HIV-infected population in the United States.

J Natl Cancer Inst 2011 May 11;103(9):753-62. Epub 2011 Apr 11.

Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852, USA.

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http://dx.doi.org/10.1093/jnci/djr076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086877PMC
May 2011

The initial step in human immunodeficiency virus type 1 GagProPol processing can be regulated by reversible oxidation.

PLoS One 2010 Oct 22;5(10):e13595. Epub 2010 Oct 22.

HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0013595PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2962637PMC
October 2010

Characterization of immune responses to capsid protein p24 of human immunodeficiency virus type 1 and implications for detection.

Clin Vaccine Immunol 2010 Aug 9;17(8):1244-51. Epub 2010 Jun 9.

Lab of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, 8800 Rockville Pike, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1128/CVI.00066-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916249PMC
August 2010

Distinct profiles of antibodies to Kaposi sarcoma-associated herpesvirus antigens in patients with Kaposi sarcoma, multicentric Castleman disease, and primary effusion lymphoma.

J Infect Dis 2010 Jun;201(12):1919-22

Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA.

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https://academic.oup.com/jid/article-lookup/doi/10.1086/6528
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http://dx.doi.org/10.1086/652869DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873114PMC
June 2010

Characterization of the activation of protein tyrosine phosphatase, receptor-type, Z polypeptide 1 (PTPRZ1) by hypoxia inducible factor-2 alpha.

PLoS One 2010 Mar 10;5(3):e9641. Epub 2010 Mar 10.

HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0009641PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835759PMC
March 2010

Radiotherapy for patients with the human immunodeficiency virus: are special precautions necessary?

Cancer 2010 Jan;116(2):273-83

Radiation Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1002/cncr.24878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409663PMC
January 2010

Identification of a potential pharmacological sanctuary for HIV type 1 in a fraction of CD4(+) primary cells.

AIDS Res Hum Retroviruses 2010 Jan;26(1):79-88

Human Retrovirus Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute-Frederick, Maryland 21702-1201, USA.

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http://dx.doi.org/10.1089/aid.2009.0044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858927PMC
January 2010

Analysis and characterization of dimerization inhibition of a multi-drug-resistant human immunodeficiency virus type 1 protease using a novel size-exclusion chromatographic approach.

Biochem J 2009 Apr;419(2):497-506

HIV and AIDS Malignancy Branch, Retrovirology Disease Section, Center for Cancer Research, National Cancer Institute, Building 10, Room 6N106, NIH (National Institutes of Health), Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1042/BJ20082068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748811PMC
April 2009

A splenic marginal zone-like peripheral blood CD27+B220- B cell population is preferentially depleted in HIV type 1-infected individuals.

AIDS Res Hum Retroviruses 2008 Apr;24(4):621-33

Human Retrovirus Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute-Frederick, Frederick, Maryland 21702, USA.

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http://www.liebertpub.com/doi/10.1089/aid.2007.0186
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http://dx.doi.org/10.1089/aid.2007.0186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716037PMC
April 2008

Using quantitative imaging techniques to assess vascularity in AIDS-related Kaposi's sarcoma.

Conf Proc IEEE Eng Med Biol Soc 2006;2006:232-5

Laboratory of Integrative & Medical Biophysics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1109/IEMBS.2006.259462DOI Listing
March 2008

Treatment of AIDS-related Kaposi's sarcoma with interleukin-12: rationale and preliminary evidence of clinical activity.

Crit Rev Immunol 2007 ;27(5):401-14

HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892-1868, USA.

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http://dx.doi.org/10.1615/critrevimmunol.v27.i5.10DOI Listing
February 2008

Using noninvasive multispectral imaging to quantitatively assess tissue vasculature.

J Biomed Opt 2007 Sep-Oct;12(5):051604

National Institutes of Health, National Institute of Child Health and Human Development, Laboratory of Integrative and Medical Biophysics, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1117/1.2801718DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2443549PMC
January 2008

Nanoparticle-Based biobarcode amplification assay (BCA) for sensitive and early detection of human immunodeficiency type 1 capsid (p24) antigen.

J Acquir Immune Defic Syndr 2007 Oct;46(2):231-7

Lab of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1097/QAI.0b013e31814a554bDOI Listing
October 2007

Potent inhibition of HIV-1 replication by novel non-peptidyl small molecule inhibitors of protease dimerization.

J Biol Chem 2007 Sep 17;282(39):28709-20. Epub 2007 Jul 17.

Department of Hematology, Kumamoto University Graduate School of Medical and Pharmaceutical Sciences, 1-1-1 Honjo, Kumamoto 860-8556, Japan.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M703938200
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http://dx.doi.org/10.1074/jbc.M703938200DOI Listing
September 2007

Hypoxia enhances the phosphorylation and cytotoxicity of ganciclovir and zidovudine in Kaposi's sarcoma-associated herpesvirus infected cells.

Cancer Res 2007 Jul;67(14):7003-10

HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-07-0939DOI Listing
July 2007

Conservation of virally encoded microRNAs in Kaposi sarcoma--associated herpesvirus in primary effusion lymphoma cell lines and in patients with Kaposi sarcoma or multicentric Castleman disease.

J Infect Dis 2007 Mar 23;195(5):645-59. Epub 2007 Jan 23.

Viral Epidemiology Section, AIDS Vaccine Program, Science Applications International Corporation-Frederick, National Cancer Institute-Frederick, Frederick, MD 21701, USA.

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https://academic.oup.com/jid/article-lookup/doi/10.1086/5114
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http://dx.doi.org/10.1086/511434DOI Listing
March 2007

Inhibition of HIV-1 replication by a peptide dimerization inhibitor of HIV-1 protease.

Antiviral Res 2006 Nov 21;72(2):89-99. Epub 2006 Apr 21.

HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, Building 10, Room 10S255, NIH, Bethesda MD 20892-1868, USA.

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http://dx.doi.org/10.1016/j.antiviral.2006.03.015DOI Listing
November 2006

Possible therapeutic vaccine strategy against human immunodeficiency virus escape from reverse transcriptase inhibitors studied in HLA-A2 transgenic mice.

J Virol 2006 Nov 18;80(21):10645-51. Epub 2006 Aug 18.

Vaccine Branch, Center for Cancer Research, National Cancer Institute, Building 10, Room 6B-04 (MSC#1578), NIH, Bethesda, MD 20892-1578, USA.

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http://dx.doi.org/10.1128/JVI.01351-05DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1641790PMC
November 2006

Poor specific T cell responses to human herpesvirus 8: A key to unleashing Kaposi sarcoma?

J Infect Dis 2006 Oct 15;194(8):1030-1. Epub 2006 Sep 15.

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http://dx.doi.org/10.1086/507649DOI Listing
October 2006

Key role for a viral lytic gene in Kaposi's sarcoma.

Authors:
Robert Yarchoan

N Engl J Med 2006 Sep;355(13):1383-5

HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.

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http://dx.doi.org/10.1056/NEJMcibr063911DOI Listing
September 2006

Genetic organization and hypoxic activation of the Kaposi's sarcoma-associated herpesvirus ORF34-37 gene cluster.

J Virol 2006 Jul;80(14):7037-51

HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-1868, USA.

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http://dx.doi.org/10.1128/JVI.00553-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1489055PMC
July 2006

Acquired immunodeficiency syndrome-related malignancies in the era of highly active antiretroviral therapy.

Int J Hematol 2006 Jul;84(1):3-11

HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892-1868, USA.

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http://link.springer.com/10.1532/IJH97.06088
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http://dx.doi.org/10.1532/IJH97.06088DOI Listing
July 2006

Activity of subcutaneous interleukin-12 in AIDS-related Kaposi sarcoma.

Blood 2006 Jun 28;107(12):4650-7. Epub 2006 Feb 28.

HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-1868, USA.

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http://dx.doi.org/10.1182/blood-2005-11-4455DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1475826PMC
June 2006

Preferential inhibition of the magnesium-dependent strand transfer reaction of HIV-1 integrase by alpha-hydroxytropolones.

Mol Pharmacol 2006 Apr 17;69(4):1454-60. Epub 2006 Jan 17.

Laboratory of Molecular Pharmacology, Bldg. 37, Room 5068, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1124/mol.105.020321DOI Listing
April 2006

Therapy insight: AIDS-related malignancies--the influence of antiviral therapy on pathogenesis and management.

Nat Clin Pract Oncol 2005 Aug;2(8):406-15; quiz 423

HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892-1868, USA.

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http://dx.doi.org/10.1038/ncponc0253DOI Listing
August 2005

Differential gene up-regulation by hypoxia-inducible factor-1alpha and hypoxia-inducible factor-2alpha in HEK293T cells.

Cancer Res 2005 Apr;65(8):3299-306

HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-04-4130DOI Listing
April 2005

Differential processing of stromal-derived factor-1alpha and stromal-derived factor-1beta explains functional diversity.

Blood 2004 Apr 2;103(7):2452-9. Epub 2003 Oct 2.

Experimental Transplantation and Immunology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1182/blood-2003-08-2857DOI Listing
April 2004

Selective expression of stromal-derived factor-1 in the capillary vascular endothelium plays a role in Kaposi sarcoma pathogenesis.

Blood 2003 Dec 7;102(12):3900-5. Epub 2003 Aug 7.

Experimental Transplantation and Immunology Branch, CCR, National Cancer Institute, National Institutes of Health, Bldg 10, Rm 12N226, MSC 1907, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1182/blood-2003-02-0641DOI Listing
December 2003

Serum inactivation contributes to the failure of stromal-derived factor-1 to block HIV-I infection in vivo.

J Leukoc Biol 2003 Nov 22;74(5):880-8. Epub 2003 Jul 22.

Experimental Transplantation and Immunology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1189/jlb.0403149DOI Listing
November 2003