Publications by authors named "Robert T Schooley"

100Publications

Airborne transmission of SARS-CoV-2.

Science 2020 10 5;370(6514):303-304. Epub 2020 Oct 5.

Institute for Applied Environmental Health, University of Maryland, College Park, MD 20742, USA.

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http://dx.doi.org/10.1126/science.abf0521DOI Listing
October 2020

Lessons Learned From the First 10 Consecutive Cases of Intravenous Bacteriophage Therapy to Treat Multidrug-Resistant Bacterial Infections at a Single Center in the United States.

Open Forum Infect Dis 2020 Sep 27;7(9):ofaa389. Epub 2020 Aug 27.

Division of Infectious Diseases and Global Public Health, University of California, San Diego, La Jolla, California, USA.

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http://dx.doi.org/10.1093/ofid/ofaa389DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519779PMC
September 2020

Treatment of COVID-19 - Evidence-Based or Personalized Medicine?

Clin Infect Dis 2020 Jul 15. Epub 2020 Jul 15.

Division of Infectious Diseases and Global Public Health, Center for Innovative Phage Applications and Therapeutics, University of California, San Diego, San Diego, California, USA.

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http://dx.doi.org/10.1093/cid/ciaa996DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7454443PMC
July 2020

Design, synthesis, and biological characterization of a new class of symmetrical polyamine-based small molecule CXCR4 antagonists.

Eur J Med Chem 2020 Aug 16;200:112410. Epub 2020 May 16.

Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, 100084, China. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2020.112410DOI Listing
August 2020

Reducing transmission of SARS-CoV-2.

Science 2020 06 27;368(6498):1422-1424. Epub 2020 May 27.

Department of Medicine, Division of Infectious Diseases and Global Public Health, School of Medicine, University of California San Diego, La Jolla, CA 92093, USA.

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http://dx.doi.org/10.1126/science.abc6197DOI Listing
June 2020

Antimicrobial Resistance - The Glass Is Half Full.

N Engl J Med 2020 04;382(14):1363-1365

From the Departments of Laboratory Medicine and Microbiology, University of Washington School of Medicine, Seattle (F.C.F.); and the Division of Infectious Diseases and Global Public Health, Center for Innovative Phage Applications and Therapeutics, University of California, San Diego, San Diego (R.T.S.).

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http://dx.doi.org/10.1056/NEJMe2002375DOI Listing
April 2020

Treat phage like living antibiotics.

Nat Microbiol 2020 03;5(3):391-392

Center for Innovative Phage Applications and Therapeutics, Division of Infectious Disease and Global Public Health, University of California San Diego, La Jolla, CA, USA.

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http://dx.doi.org/10.1038/s41564-019-0666-4DOI Listing
March 2020

Predictors of Acute Liver Failure in Patients With Acute Hepatitis A: An Analysis of the 2016-2018 San Diego County Hepatitis A Outbreak.

Open Forum Infect Dis 2019 Nov 5;6(11):ofz467. Epub 2019 Nov 5.

Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of California, San Diego, La Jolla, California, USA.

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http://dx.doi.org/10.1093/ofid/ofz467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868431PMC
November 2019

What's Old Is New Again: Bacteriophage Therapy in the 21st Century.

Antimicrob Agents Chemother 2019 12 20;64(1). Epub 2019 Dec 20.

Division of Infectious Diseases and Global Public Health, Center for Innovative Phage Applications and Therapeutics, University of California, San Diego, San Diego, California.

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http://dx.doi.org/10.1128/AAC.01987-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187564PMC
December 2019

Molecular Detection of spp. in Rodents Trapped in the Mozambique Island City, Nampula Province, Mozambique.

EC Microbiol 2018 Dec 27;14(12):813-821. Epub 2018 Nov 27.

Parasitology Laboratory, Microbiology Department, Faculty of Medicine, Eduardo Mondlane University, Maputo, Mozambique.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824726PMC
December 2018

Discovery of New Inhibitors of Hepatitis C Virus NS3/4A Protease and Its D168A Mutant.

ACS Omega 2019 Oct 2;4(16):16999-17008. Epub 2019 Oct 2.

Skaggs School of Pharmacy and Pharmaceutical Sciences, Department of Chemistry and Biochemistry, and School of Medicine, University of California San Diego, La Jolla, California 92093, United States.

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http://dx.doi.org/10.1021/acsomega.9b02491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796237PMC
October 2019

The Virome of Cerebrospinal Fluid: Viruses Where We Once Thought There Were None.

Front Microbiol 2019 6;10:2061. Epub 2019 Sep 6.

Department of Pathology, University of California, San Diego, San Diego, CA, United States.

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http://dx.doi.org/10.3389/fmicb.2019.02061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742758PMC
September 2019

Octadecyloxyethyl benzyl tenofovir: A novel tenofovir diester provides sustained intracellular levels of tenofovir diphosphate.

Antiviral Res 2019 11 21;171:104614. Epub 2019 Sep 21.

Department of Medicine, Division of Infectious Disease and Global Public Health, University of California San Diego, La Jolla, CA, 92093, USA.

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http://dx.doi.org/10.1016/j.antiviral.2019.104614DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927535PMC
November 2019

Successful adjunctive use of bacteriophage therapy for treatment of multidrug-resistant Pseudomonas aeruginosa infection in a cystic fibrosis patient.

Infection 2019 Aug 17;47(4):665-668. Epub 2019 May 17.

Division of Infectious Diseases and Global Health, University of California, San Diego, 4510 Executive Drive, Suite P7, La Jolla, San Diego, CA, 92121, USA.

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http://dx.doi.org/10.1007/s15010-019-01319-0DOI Listing
August 2019

Discovery and Computational Analyses of Novel Small Molecule Zika Virus Inhibitors.

Molecules 2019 Apr 13;24(8). Epub 2019 Apr 13.

Department of Medicine, Division of Infectious Diseases, School of Medicine, University of California San Diego, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.3390/molecules24081465DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514826PMC
April 2019

High affinity CXCR4 inhibitors generated by linking low affinity peptides.

Eur J Med Chem 2019 Jun 1;172:174-185. Epub 2019 Apr 1.

Department of Medicine, Division of Infectious Diseases, School of Medicine, University of California San Diego, La Jolla, CA, 92037, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2019.03.056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677133PMC
June 2019

Novel bacteriophage therapy for treatment of left ventricular assist device infection.

J Heart Lung Transplant 2019 04 7;38(4):475-476. Epub 2019 Jan 7.

Division of Infectious Diseases and Global Public Health, Department of Medicine, and University of California San Diego, La Jolla, California, USA.

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http://dx.doi.org/10.1016/j.healun.2019.01.001DOI Listing
April 2019

Virtual Screening, Biological Evaluation, and 3D-QSAR Studies of New HIV-1 Entry Inhibitors That Function via the CD4 Primary Receptor.

Molecules 2018 Nov 20;23(11). Epub 2018 Nov 20.

Department of Medicine, Division of Infectious Diseases, School of Medicine, University of California San Diego, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.3390/molecules23113036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278378PMC
November 2018

Maternally Acquired Zika Antibodies Enhance Dengue Disease Severity in Mice.

Cell Host Microbe 2018 11;24(5):743-750.e5

Inflammation Biology, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA; Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S19313128183049
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http://dx.doi.org/10.1016/j.chom.2018.09.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250068PMC
November 2018

The human microbiome: implications for health and disease, including HIV infection.

Top Antivir Med 2018 Sep;26(3):75-78

University of California San Diego, La Jolla, CA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291299PMC
September 2018

Skating to Where the Puck Is Going to Be.

Clin Infect Dis 2017 01;64(1):1-2

Department of Laboratory Medicine, University of Washington, Seattle.

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http://dx.doi.org/10.1093/cid/ciw661DOI Listing
January 2017

Our Warming Planet: Is the HIV-1-Infected Population in the Crosshairs.

Top Antivir Med 2016 Jul/Aug;26(2):67-70

University of California San Diego, La Jolla, CA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017129PMC
June 2018

Reply to Christopher and Kortepeter.

Clin Infect Dis 2015 Nov 14;61(9):1489-90. Epub 2015 Jul 14.

Division of Infectious Diseases, University of California, San Diego.

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http://dx.doi.org/10.1093/cid/civ567DOI Listing
November 2015

Near patient CD4 count in a hospitalized HIV patient population.

Cytometry B Clin Cytom 2017 11 27;92(6):451-455. Epub 2015 May 27.

MBio Diagnostics Inc., 5603 Arapahoe Ave, Suite 1, Boulder, Colorado, 80303.

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http://dx.doi.org/10.1002/cyto.b.21248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595587PMC
November 2017

Editorial Commentary: All's (Almost) Quiet on the Western Front: Will We Be Ready for the Next War?

Clin Infect Dis 2015 Aug 22;61(4):503-5. Epub 2015 Apr 22.

University of California, San Diego.

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http://dx.doi.org/10.1093/cid/civ337DOI Listing
August 2015

Determination of receptor specificities for whole influenza viruses using multivalent glycan arrays.

Chem Commun (Camb) 2015 Mar;51(25):5326-9

Department of Chemistry and Biochemistry, University of California San Diego, 9500 Gilman Drive, San Diego, CA 92093-0358, USA.

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http://dx.doi.org/10.1039/c4cc08613aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359031PMC
March 2015

Relationship of HIV reservoir characteristics with immune status and viral rebound kinetics in an HIV therapeutic vaccine study.

AIDS 2014 Nov;28(18):2649-57

aBrigham and Women's Hospital, Harvard Med School bHarvard School of Public Health, Boston, Massachusetts cCancer and Inflammation Program, Laboratory of Experimental Immunology, Leidos Biomedical Research Institute, Frederick National Laboratory for Cancer Research, Frederick, Maryland dRagon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, Massachusetts eMonogram Biosciences fUniversity of California, San Diego, La Jolla, California gCase Western Reserve University, Cleveland, Ohio, USA.

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http://dx.doi.org/10.1097/QAD.0000000000000478DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267919PMC
November 2014

Innovative strategies for transforming internal medicine residency training in resource-limited settings: the Mozambique experience.

Acad Med 2014 Aug;89(8 Suppl):S78-82

Dr. Mocumbi is professor, Instituto Nacional de Saúde and Department of Medicine, Faculdade de Medicina, Universidade Eduardo Mondlane, Maputo, Mozambique. Dr. Carrilho is associate professor, Department of Pathology, Faculdade de Medicina, Universidade Eduardo Mondlane and Hospital Central de Maputo, Maputo, Mozambique. Dr. Aronoff-Spencer is codirector, Distributed Health Labs and Medical Education Partnership Initiative, and informatics coordinator and VA staff physician in infectious diseases (HIV), University of California, San Diego, San Diego, California. Dr. Funzamo is medical researcher, Instituto Nacional de Saúde, Ministério da Saúde and Faculdade de Medicina, Universidade Eduardo Mondlane, Maputo, Mozambique. Dr. Patel is professor, Department of Medicine, Hospital Central de Maputo and Faculdade de Medicina, Universidade Eduardo Mondlane, Maputo, Mozambique, and University of California, San Diego, San Diego, California. Dr. Preziosi is assistant professor of medicine and clinical director for the residents, University of California, San Diego, San Diego, California. Dr. Lederer is Health Sciences assistant clinical professor, Department of Medicine, University of California, San Diego, San Diego, California. Dr. Tilghman is assistant professor of medicine, Division of Infectious Diseases, University of California, San Diego, San Diego, California. Dr. Benson is professor of medicine and director, Infectious Disease Training Program, Divisions of Infectious Diseases and Global Public Health, and director, Antiviral Research Center, University of California, San Diego, San Diego, California. Dr. Badaró is professor, Universidade Federal da Bahia, Salvador-Bahia, Brazil. Prof. Nguenha is head, Mozambique Institute for Health Education and Research, Maputo, Mozambique. Dr. Schooley is professor of medicine and head, Division of Infectious Diseases, University of California, San Diego, San Diego, California. Dr. Noormahomed is professor, Faculdade de M

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http://dx.doi.org/10.1097/ACM.0000000000000331DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116633PMC
August 2014

Relationship of vitamin D insufficiency to AIDS-associated Kaposi's sarcoma outcomes: retrospective analysis of a prospective clinical trial in Zimbabwe.

Int J Infect Dis 2014 Jul 21;24:6-10. Epub 2014 Apr 21.

Department of Medicine, Division of Infectious Diseases, University of Colorado Denver, 12700 E. 19(th) Avenue, Mail Stop B168, Aurora, CO 80045, USA.

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http://dx.doi.org/10.1016/j.ijid.2014.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070314PMC
July 2014

The fragile relationship between hepatitis C virus and its human host.

Top Antivir Med 2014 Jan;21(5):148-51

University of California San Diego, La Jolla, CA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148848PMC
January 2014

Influenza A penetrates host mucus by cleaving sialic acids with neuraminidase.

Virol J 2013 Nov 22;10:321. Epub 2013 Nov 22.

Department of Cellular and Molecular Medicine, University of California San Diego, 9500 Gilman Dr, La Jolla 92093, California, USA.

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http://dx.doi.org/10.1186/1743-422X-10-321DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842836PMC
November 2013

Reply to Messori et al.

Clin Infect Dis 2013 Dec 17;57(12):1784-5. Epub 2013 Oct 17.

Federal University of Bahia, Multidisciplinary Institute of Health, Vitória da Conquista, Brazil.

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http://dx.doi.org/10.1093/cid/cit591DOI Listing
December 2013

Inhibitory and combinatorial effect of diphyllin, a v-ATPase blocker, on influenza viruses.

Antiviral Res 2013 Sep 29;99(3):371-82. Epub 2013 Jun 29.

Division of Infectious Disease, School of Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, United Sates; Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, 9420 Athena Circle, La Jolla, CA 92037, United States; School of Veterinary Medicine, National Taiwan University, No. 1, Sec. 4, Roosevelt Road, Taipei 10617, Taiwan.

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http://dx.doi.org/10.1016/j.antiviral.2013.06.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787953PMC
September 2013

Performance evaluation of the MBio Diagnostics point-of-care CD4 counter.

J Immunol Methods 2013 Jan 11;387(1-2):107-13. Epub 2012 Oct 11.

Division of Infectious Diseases, University of California, 9500 Gilman Drive, MC 0711, San Diego, CA 92093, USA.

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http://dx.doi.org/10.1016/j.jim.2012.10.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529779PMC
January 2013

Hepatitis C virus therapeutics: at the end of the beginning.

Top Antivir Med 2012 Apr-May;20(1):17-9

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190617PMC
August 2012

Does lipid emulsion reduce amphotericin B nephrotoxicity? A systematic review and meta-analysis.

Clin Infect Dis 2012 Jun 5;54(12):1774-7. Epub 2012 Apr 5.

Federal University of Bahia, University Hospital Prof. Edgard Santos, Salvador-Bahia, Brazil.

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http://dx.doi.org/10.1093/cid/cis290DOI Listing
June 2012

Evaluation of ITX 5061, a scavenger receptor B1 antagonist: resistance selection and activity in combination with other hepatitis C virus antivirals.

J Infect Dis 2012 Feb;205(4):656-62

State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Institute of Infectious Diseases, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.

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http://dx.doi.org/10.1093/infdis/jir802DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266130PMC
February 2012

Flow cytometric screening for anti-leishmanials in a human macrophage cell line.

Exp Parasitol 2010 Dec 9;126(4):617-20. Epub 2010 Jun 9.

Division of Infectious Diseases, University of California, San Diego, CA 92103, USA.

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http://dx.doi.org/10.1016/j.exppara.2010.06.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939291PMC
December 2010

Rong's numbers: accelerating progress in HCV therapeutic research.

Sci Transl Med 2010 May;2(33):33ps25

Division of Infectious Diseases, University of California, San Diego, San Diego, CA 92093, USA.

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http://dx.doi.org/10.1126/scitranslmed.3001183DOI Listing
May 2010

Lessons from HIV therapy applied to viral hepatitis therapy: summary of a workshop.

Am J Gastroenterol 2010 May 19;105(5):989-1004; quiz 988, 1005. Epub 2010 Jan 19.

Department of Medicine, San Francisco Veterans Affairs Medical Center, San Francisco, California 94121, USA.

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http://dx.doi.org/10.1038/ajg.2009.726DOI Listing
May 2010

The octadecyloxyethyl ester of (S)-9-[3-hydroxy-2-(phosphonomethoxy) propyl]adenine is a potent and selective inhibitor of hepatitis C virus replication in genotype 1A, 1B, and 2A replicons.

Antimicrob Agents Chemother 2009 Jun 16;53(6):2660-2. Epub 2009 Mar 16.

San Diego Veterans Medical Research Foundation and the Department of Medicine, Division of Infectious Disease, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0676, USA.

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http://aac.asm.org/content/53/6/2660.full.pdf
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http://aac.asm.org/cgi/doi/10.1128/AAC.01546-08
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http://dx.doi.org/10.1128/AAC.01546-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687240PMC
June 2009

Running with scissors: using antiretroviral therapy without monitoring viral load.

Clin Infect Dis 2008 May;46(10):1598-600

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http://dx.doi.org/10.1086/587110DOI Listing
May 2008

Synergy of a hepatitis C virus (HCV) NS4A antagonist in combination with HCV protease and polymerase inhibitors.

Antimicrob Agents Chemother 2008 May 10;52(5):1862-4. Epub 2008 Mar 10.

Division of Infectious Diseases, Department of Medicine, University of California, 9500 Gilman Drive, MC 0711, La Jolla, CA 92093, USA.

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http://dx.doi.org/10.1128/AAC.01208-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2346627PMC
May 2008

3-drug synergistic interactions of small molecular inhibitors of hepatitis C virus replication.

J Infect Dis 2008 Jan;197(1):42-5

Department of Medicine, Division of Infectious Diseases, University of California, San Diego, La Jolla, USA.

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http://dx.doi.org/10.1086/524062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010224PMC
January 2008

Immunophenotypic alterations in acute and early HIV infection.

Clin Immunol 2007 Dec 3;125(3):299-308. Epub 2007 Oct 3.

Department of Immunology/Microbiology, Rush University Medical Center, Chicago, IL 60612, USA.

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http://dx.doi.org/10.1016/j.clim.2007.08.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702986PMC
December 2007

No cure yet for HIV-1, but therapeutic research presses on.

J Infect Dis 2007 Mar 30;195(6):770-2. Epub 2007 Jan 30.

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http://dx.doi.org/10.1086/511830DOI Listing
March 2007