Robert T Bailer

Robert T Bailer

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Robert T Bailer

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Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability.

Immunity 2019 Nov 12;51(5):915-929.e7. Epub 2019 Nov 12.

Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; International AIDS Vaccine Initiative, Neutralizing Antibody Center at The Scripps Research Institute, La Jolla, CA 92037, USA; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2019.10.008DOI Listing
November 2019

Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual.

Immunity 2019 03 12;50(3):677-691.e13. Epub 2019 Mar 12.

Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10747613193007
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http://dx.doi.org/10.1016/j.immuni.2019.02.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555550PMC
March 2019

Structural Survey of Broadly Neutralizing Antibodies Targeting the HIV-1 Env Trimer Delineates Epitope Categories and Characteristics of Recognition.

Structure 2019 01 21;27(1):196-206.e6. Epub 2018 Nov 21.

Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA; Department of Biochemistry and Molecular Biophysics & Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY 10032, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09692126183036
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http://dx.doi.org/10.1016/j.str.2018.10.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664815PMC
January 2019

Chimpanzee Adenovirus Vector Ebola Vaccine.

N Engl J Med 2017 03 26;376(10):928-938. Epub 2014 Nov 26.

From the Vaccine Research Center (J.E.L., A.D.D., D.A.S., E.E.C., L.N., M.E.E., N.M.B., A.P., S.S., I.J.G., S.A.P., L.A.H., C.S.H., G.Y., R.T.B., R.M.S., M.R., J.R.M., R.A.K., N.J.S., B.S.G.) and the Biostatistics Research Branch, Division of Clinical Research (Z.H., G.J.), National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD; GlaxoSmithKline Vaccines, Rixensart, Belgium (F.R.); ReiThera, Rome (A.N., S.C.), and CEINGE and the Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples (A.N.) - both in Italy; and Keires, Basel, Switzerland (R.C.).

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http://dx.doi.org/10.1056/NEJMoa1410863DOI Listing
March 2017

Effect of HIV Antibody VRC01 on Viral Rebound after Treatment Interruption.

N Engl J Med 2016 11 9;375(21):2037-2050. Epub 2016 Nov 9.

From the University of Pennsylvania (K.J.B., D.B.S., B.S., G.H.L., E.F.K., M.B., J.A.H., P.T.) and Children's Hospital of Philadelphia (N.B.T.) - both in Philadelphia; the Laboratory of Immunoregulation (M.C.S., J.S.J., M.E.P., J.B., E.W.R., K.E.C., S.M., A.S.F., T.-W.C.), Biostatistics Research Branch (M.A.P.), Vaccine Research Center (P.J.M., S.J.O., A.R.S., N.A.D.-R., R.T.B., J.E.L., R.M.L., B.S.G., R.A.K., J.R.M.), and Division of AIDS (R.L.T.), National Institute of Allergy and Infectious Diseases and National Institutes of Health (NIH), and the Critical Care Medicine Department, Clinical Center, NIH (C.A.S., R.W.K.), Bethesda, the AIDS Clinical Trials Group, Silver Spring (K.O.), and Columbus Technologies and Services, Greenbelt (R.L.T.) - all in Maryland; Harvard T.H. Chan School of Public Health, Boston (L.J.H.); the University of Alabama at Birmingham, Birmingham (E.T.O., M.M.); Frontier Science and Technology Research Foundation, Amherst, NY (B.J.); and the University of California, San Diego, La Jolla (E.V.C.).

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http://dx.doi.org/10.1056/NEJMoa1608243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292134PMC
November 2016

Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection.

Cell 2015 04 9;161(3):470-485. Epub 2015 Apr 9.

Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA; Department of Biochemistry and Molecular Biophysics and Department of Systems Biology, Columbia University, New York, NY 10032, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2015.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706178PMC
April 2015

Prevalence of broadly neutralizing antibody responses during chronic HIV-1 infection.

AIDS 2014 Jan;28(2):163-9

aTheoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos, New Mexico bCenter for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts cVaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland dDepartment of Surgery, Duke University Medical Center, Durham, North Carolina, USA.

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http://dx.doi.org/10.1097/QAD.0000000000000106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042313PMC
January 2014

Isolation of human monoclonal antibodies from peripheral blood B cells.

Nat Protoc 2013 Oct 12;8(10):1907-15. Epub 2013 Sep 12.

HIV-Specific Immunity Section, Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases (NIAID), US National Institutes of Health (NIH), Bethesda, Maryland, USA.

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http://www.nature.com/doifinder/10.1038/nprot.2013.117
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http://dx.doi.org/10.1038/nprot.2013.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844175PMC
October 2013

A computational framework for the analysis of peptide microarray antibody binding data with application to HIV vaccine profiling.

J Immunol Methods 2013 Sep 13;395(1-2):1-13. Epub 2013 Jun 13.

Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, M2-C200, PO Box 19024, Seattle, WA 98109-1024, United States.

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http://dx.doi.org/10.1016/j.jim.2013.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999921PMC
September 2013

Broad and potent neutralization of HIV-1 by a gp41-specific human antibody.

Nature 2012 Nov 18;491(7424):406-12. Epub 2012 Sep 18.

HIV-Specific Immunity Section, Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://www.nature.com/articles/nature11544
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http://dx.doi.org/10.1038/nature11544DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854285PMC
November 2012

HIV-1 neutralization coverage is improved by combining monoclonal antibodies that target independent epitopes.

J Virol 2012 Mar 18;86(6):3393-7. Epub 2012 Jan 18.

Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1128/JVI.06745-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302320PMC
March 2012

Priming immunization with DNA augments immunogenicity of recombinant adenoviral vectors for both HIV-1 specific antibody and T-cell responses.

PLoS One 2010 Feb 2;5(2):e9015. Epub 2010 Feb 2.

Vaccine Research Center, Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0009015PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2814848PMC
February 2010

Systemic and mucosal T-lymphocyte activation induced by recombinant adenovirus vaccines in rhesus monkeys.

J Virol 2009 Oct 5;83(20):10596-604. Epub 2009 Aug 5.

Division of Viral Pathogenesis, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA.

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http://jvi.asm.org/cgi/doi/10.1128/JVI.01170-09
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http://dx.doi.org/10.1128/JVI.01170-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2753133PMC
October 2009

Characterization of SARS-CoV-specific memory T cells from recovered individuals 4 years after infection.

Arch Virol 2009 13;154(7):1093-9. Epub 2009 Jun 13.

Department of Immunology, Sun Yat-Sen University, Guangzhou, People's Republic of China.

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http://dx.doi.org/10.1007/s00705-009-0409-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796960PMC
July 2009

Replication-defective adenovirus vectors with multiple deletions do not induce measurable vector-specific T cells in human trials.

J Virol 2009 Jun 1;83(12):6318-22. Epub 2009 Apr 1.

Immunology Laboratory, Immunology Core Section, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1128/JVI.00384-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687372PMC
June 2009

A West Nile virus DNA vaccine induces neutralizing antibody in healthy adults during a phase 1 clinical trial.

J Infect Dis 2007 Dec;196(12):1732-40

Vaccine Research Center, Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 40 Convent Drive, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1086/523650DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714735PMC
December 2007

Phase I clinical evaluation of a six-plasmid multiclade HIV-1 DNA candidate vaccine.

Vaccine 2007 May 7;25(20):4085-92. Epub 2007 Mar 7.

Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 40 Convent Drive, Building 40, Bethesda, MD 20892-3017, USA.

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http://dx.doi.org/10.1016/j.vaccine.2007.02.050DOI Listing
May 2007