Publications by authors named "Robert Sutton"

100Publications

Pediatric In-Hospital Cardiac Arrest and Cardiopulmonary Resuscitation in the United States: A Review.

JAMA Pediatr 2020 Nov 23. Epub 2020 Nov 23.

Department of Anesthesiology and Critical Care Medicine, Division of Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

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November 2020

Chaiqin chengqi decoction alleviates severity of acute pancreatitis via inhibition of TLR4 and NLRP3 inflammasome: Identification of bioactive ingredients via pharmacological sub-network analysis and experimental validation.

Phytomedicine 2020 Dec 1;79:153328. Epub 2020 Sep 1.

Department of Integrated Traditional Chinese and Western Medicine, Sichuan Provincial Pancreatitis Centre and West China-Liverpool Biomedical Research Centre, West China Hospital, Sichuan University, Chengdu 610041, China. Electronic address:

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December 2020

Hemoconcentration is associated with early faster fluid rate and increased risk of persistent organ failure in acute pancreatitis patients.

JGH Open 2020 Aug 13;4(4):684-691. Epub 2020 Mar 13.

Department and Laboratory of Integrated Traditional Chinese and Western Medicine, Sichuan Provincial Pancreatitis Centre and West China-Liverpool Biomedical Research Centre, West China Hospital Sichuan University Chengdu China.

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August 2020

Deployment of a Clinical Pathway to Improve Postcardiac Arrest Care: A Before-After Study.

Pediatr Crit Care Med 2020 10;21(10):e898-e907

Division of Pediatric Critical Care Medicine, Department of Anesthesiology and Critical Care, Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.

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October 2020

Pediatric Resuscitation Practices During the Coronavirus Disease 2019 Pandemic.

Pediatr Crit Care Med 2020 09;21(9):e651-e660

Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.

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September 2020

Pediatric cardiopulmonary resuscitation quality during intra-hospital transport.

Resuscitation 2020 07 15;152:123-130. Epub 2020 May 15.

Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, 3401 Civic Center Boulevard, Philadelphia, PA 19104, United States. Electronic address:

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July 2020

Parenchymal pressure injury Ca entry mechanism in pancreatitis.

Authors:
Robert Sutton

Cell Calcium 2020 Apr 19;88:102208. Epub 2020 Apr 19.

Liverpool Pancreatitis Research Group, Institute of Translational Medicine, University of Liverpool and Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK. Electronic address:

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April 2020

Aqueous extraction from dachengqi formula granules reduces the severity of mouse acute pancreatitis via inhibition of pancreatic pro-inflammatory signalling pathways.

J Ethnopharmacol 2020 Jul 18;257:112861. Epub 2020 Apr 18.

Department of Integrated Traditional Chinese and Western Medicine, Sichuan Provincial Pancreatitis Centre and West China-Liverpool Biomedical Research Centre, West China Hospital, Sichuan University, Chengdu, 610041, China. Electronic address:

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July 2020

Providing Early Attending Physician Expertise via Telemedicine to Improve Rapid Response Team Evaluations.

Pediatr Crit Care Med 2020 05;21(5):e221-e227

Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

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May 2020

Improving Small Intestinal Motility in Experimental Acute Necrotising Pancreatitis by Modulating the CPI-17/MLCP Pathway Using Chaiqin Chengqi Decoction.

Evid Based Complement Alternat Med 2020 10;2020:9189457. Epub 2020 Feb 10.

Department of Integrated Traditional Chinese and Western Medicine, Sichuan Provincial Pancreatitis Centre and West China-Liverpool Biomedical Research Centre, West China Hospital, Sichuan University, Chengdu, China.

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February 2020

Deviations from AHA guidelines during pediatric cardiopulmonary resuscitation are associated with decreased event survival.

Resuscitation 2020 04 11;149:89-99. Epub 2020 Feb 11.

Department of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.

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April 2020

The authors reply.

Crit Care Med 2020 02;48(2):e160-e161

Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia & University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

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February 2020

Early Rapid Fluid Therapy Is Associated with Increased Rate of Noninvasive Positive-Pressure Ventilation in Hemoconcentrated Patients with Severe Acute Pancreatitis.

Dig Dis Sci 2020 09 7;65(9):2700-2711. Epub 2020 Jan 7.

Department and Laboratory of Integrated Traditional Chinese and Western Medicine, Sichuan Provincial Pancreatitis Center and West China-Liverpool Biomedical Research Center, West China Hospital, Sichuan University, No. 37 Wannan Guoxue Alley, Chengdu, 610041, Sichuan Province, China.

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September 2020

Altered Bioenergetics of Blood Cell Sub-Populations in Acute Pancreatitis Patients.

J Clin Med 2019 Dec 13;8(12). Epub 2019 Dec 13.

Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool L69 3BX, UK.

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December 2019

Prevalence and Outcomes of Pediatric In-Hospital Cardiac Arrest Associated With Pulmonary Hypertension.

Pediatr Crit Care Med 2020 04;21(4):305-313

Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.

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April 2020

Performance of a Clinical Decision Support Tool to Identify PICU Patients at High Risk for Clinical Deterioration.

Pediatr Crit Care Med 2020 02;21(2):129-135

Department of Anesthesiology and Critical Care Medicine, Division of Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA.

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February 2020

Simulating blood pressure and end tidal CO2 in a CPR training manikin.

Comput Methods Programs Biomed 2019 Oct 3;180:105009. Epub 2019 Aug 3.

Department of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, 34th Street and Civic Center Blvd Philadelphia, PA 19104, USA; The Perelman School of Medicine, University of Pennsylvania, 3400 Civic Center Blvd, Philadelphia, PA 19104, USA. Electronic address:

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October 2019

Pancreas-specific plasma amylase for assessment and diagnosis of chronic pancreatitis: New insights on an old topic.

United European Gastroenterol J 2019 08 16;7(7):955-964. Epub 2019 Apr 16.

Centre for Pancreatic Diseases, Department of Gastroenterology and Hepatology, Aalborg University Hospital, Aalborg, Denmark.

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August 2019

Matched Retrospective Cohort Study of Thiamine to Treat Persistent Hyperlactatemia in Pediatric Septic Shock.

Pediatr Crit Care Med 2019 09;20(9):e452-e456

Department of Anesthesiology and Critical Care, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

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September 2019

Duration of organ failure impacts mortality in acute pancreatitis.

Gut 2020 03 11;69(3):604-605. Epub 2019 Feb 11.

Liverpool Pancreatitis Study Group, Royal Liverpool University Hospital and Institute of Translational Medicine, University of Liverpool, Liverpool, UK.

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March 2020

The heparin-binding proteome in normal pancreas and murine experimental acute pancreatitis.

PLoS One 2019 18;14(6):e0217633. Epub 2019 Jun 18.

Liverpool Pancreatitis Research Group, Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, United Kingdom.

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February 2020

Antibiotic therapy in acute pancreatitis: From global overuse to evidence based recommendations.

Authors:
Andrea Párniczky Tamás Lantos Eszter Margit Tóth Zsolt Szakács Szilárd Gódi Roland Hágendorn Dóra Illés Balázs Koncz Katalin Márta Alexandra Mikó Dóra Mosztbacher Balázs Csaba Németh Dániel Pécsi Anikó Szabó Ákos Szücs Péter Varjú Andrea Szentesi Erika Darvasi Bálint Erőss Ferenc Izbéki László Gajdán Adrienn Halász Áron Vincze Imre Szabó Gabriella Pár Judit Bajor Patrícia Sarlós József Czimmer József Hamvas Tamás Takács Zoltán Szepes László Czakó Márta Varga János Novák Barnabás Bod Attila Szepes János Sümegi Mária Papp Csaba Góg Imola Török Wei Huang Qing Xia Ping Xue Weiqin Li Weiwei Chen Natalia V Shirinskaya Vladimir L Poluektov Anna V Shirinskaya Péter Jenő Hegyi Marian Bátovský Juan Armando Rodriguez-Oballe Isabel Miguel Salas Javier Lopez-Diaz J Enrique Dominguez-Munoz Xavier Molero Elizabeth Pando María Lourdes Ruiz-Rebollo Beatriz Burgueño-Gómez Yu-Ting Chang Ming-Chu Chang Ajay Sud Danielle Moore Robert Sutton Amir Gougol Georgios I Papachristou Yaroslav Mykhailovych Susak Illia Olehovych Tiuliukin António Pedro Gomes Maria Jesus Oliveira David João Aparício Marcel Tantau Floreta Kurti Mila Kovacheva-Slavova Stephanie-Susanne Stecher Julia Mayerle Goran Poropat Kshaunish Das Marco Vito Marino Gabriele Capurso Ewa Małecka-Panas Hubert Zatorski Anita Gasiorowska Natalia Fabisiak Piotr Ceranowicz Beata Kuśnierz-Cabala Joana Rita Carvalho Samuel Raimundo Fernandes Jae Hyuck Chang Eun Kwang Choi Jimin Han Sara Bertilsson Hanaz Jumaa Gabriel Sandblom Sabite Kacar Minas Baltatzis Aliaksandr Vladimir Varabei Vizhynis Yeshy Serge Chooklin Andriy Kozachenko Nikolay Veligotsky Péter Hegyi

Pancreatology 2019 Jun 19;19(4):488-499. Epub 2019 Apr 19.

Institute for Translational Medicine, Szentágothai Research Centre, Medical School, University of Pécs, Pécs, Hungary; First Department of Medicine, Faculty of Medicine, University of Szeged, Szeged, Hungary; Division of Translational Medicine, First Department of Medicine, Medical School, University of Pécs, Pécs, Hungary; Hungarian Academy of Sciences-University of Szeged, Momentum Gastroenterology Multidisciplinary Research Group, Szeged, Hungary. Electronic address:

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June 2019

Mitochondrial Targeting of Antioxidants Alters Pancreatic Acinar Cell Bioenergetics and Determines Cell Fate.

Int J Mol Sci 2019 Apr 5;20(7). Epub 2019 Apr 5.

Department of Cellular & Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool L69 3BX, UK.

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April 2019

Hemodynamic effects of chest compression interruptions during pediatric in-hospital cardiopulmonary resuscitation.

Resuscitation 2019 06 1;139:1-8. Epub 2019 Apr 1.

The Children's Hospital of Philadelphia, Department of Anesthesiology and Critical Care Medicine, 3401 Civic Center Blvd, Philadelphia, PA 19104, United States.

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June 2019

Hypertriglyceridaemia-associated acute pancreatitis: diagnosis and impact on severity.

HPB (Oxford) 2019 09 15;21(9):1240-1249. Epub 2019 Mar 15.

Department of Integrated Traditional Chinese and Western Medicine, Sichuan Provincial Pancreatitis Centre and West China-Liverpool Biomedical Research Centre, West China Hospital of Sichuan University, Chengdu, China. Electronic address:

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September 2019

Hemodynamic-Directed Cardiopulmonary Resuscitation Improves Neurologic Outcomes and Mitochondrial Function in the Heart and Brain.

Crit Care Med 2019 03;47(3):e241-e249

Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

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March 2019

Mechanisms of Pancreatic Injury Induced by Basic Amino Acids Differ Between L-Arginine, L-Ornithine, and L-Histidine.

Front Physiol 2018 15;9:1922. Epub 2019 Jan 15.

Liverpool Pancreatitis Study Group, Royal Liverpool University Hospital, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom.

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January 2019

Rhythm characteristics and patterns of change during cardiopulmonary resuscitation for in-hospital paediatric cardiac arrest.

Resuscitation 2019 02 9;135:45-50. Epub 2019 Jan 9.

Department of Circulation and Medical Imaging, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, NO-7491, Trondheim, Norway; Department of Anaesthesia and Intensive Care Medicine, St.Olav Hospital, Trondheim, Norway.

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February 2019

Ethyl pyruvate and analogs as potential treatments for acute pancreatitis: A review of in vitro and in vivo studies.

Pancreatology 2019 Mar 25;19(2):209-216. Epub 2018 Dec 25.

Department of Integrated Traditional Chinese and Western Medicine, Sichuan Provincial Pancreatitis Centre and West China-Liverpool Biomedical Research Centre, West China Hospital, Sichuan University, Chengdu 610041, China. Electronic address:

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March 2019

Response by Berg et al to Letter Regarding Article, "Association Between Diastolic Blood Pressure During Pediatric In-Hospital Cardiopulmonary Resuscitation and Survival".

Circulation 2018 11;138(22):2588-2589

Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine.

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November 2018

RCAN1 is a marker of oxidative stress, induced in acute pancreatitis.

Pancreatology 2018 Oct 16;18(7):734-741. Epub 2018 Aug 16.

Pancreas Cancer Research Lab, Dept. of Clinical Intervention and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden; Centre for Digestive Diseases, Karolinska University Hospital, Stockholm, Sweden. Electronic address:

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October 2018

End-tidal carbon dioxide during pediatric in-hospital cardiopulmonary resuscitation.

Resuscitation 2018 12 15;133:173-179. Epub 2018 Aug 15.

Department of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, University of Pennsylvania, 3400 Civic Center Blvd, Philadelphia, PA 19104, United States.

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December 2018

Biology, role and therapeutic potential of circulating histones in acute inflammatory disorders.

J Cell Mol Med 2018 10 7;22(10):4617-4629. Epub 2018 Aug 7.

Liverpool Pancreatitis Research Group, Royal Liverpool University Hospital and Institute of Translational Medicine, University of Liverpool, Liverpool, UK.

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October 2018

Acute parotitis due to MRSA causing Lemierre's syndrome.

Oxf Med Case Reports 2018 May 31;2018(5):omx056. Epub 2018 May 31.

Liverpool NIHR Pancreas Biomedical Research Unit, Royal Liverpool University Hospital, University of Liverpool, Liverpool L69 3GA, UK.

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May 2018

Earlier surgery improves outcomes from painful chronic pancreatitis.

Medicine (Baltimore) 2018 May;97(19):e0651

Department of Pancreatic Surgery Division of General Practice Department of Integrated Traditional Chinese and Western Medicine (WH), West China Hospital, Sichuan University, Chengdu, China NIHR Liverpool Pancreas Biomedical Research Unit, Royal Liverpool University Hospital, University of Liverpool, Liverpool, UK Department of Surgery (JAW), University of Auckland, Auckland, New Zealand.

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May 2018

Intracellular rupture, exocytosis and actin interaction of endocytic vacuoles in pancreatic acinar cells: initiating events in acute pancreatitis.

J Physiol 2018 07 6;596(13):2547-2564. Epub 2018 Jun 6.

Department of Cellular and Molecular Physiology and NIHR Liverpool Pancreas Biomedical Research Unit, University of Liverpool, Liverpool, UK.

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July 2018

Physiology-directed cardiopulmonary resuscitation: advances in precision monitoring during cardiac arrest.

Curr Opin Crit Care 2018 06;24(3):143-150

Division of Critical Care Medicine, Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

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June 2018

EPC/HPSG evidence-based guidelines for the management of pediatric pancreatitis.

Pancreatology 2018 Mar 4;18(2):146-160. Epub 2018 Jan 4.

Institute for Translational Medicine, University of Pécs, Pécs, Hungary; First Department of Medicine, University of Szeged, Szeged, Hungary. Electronic address:

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March 2018

Pediatric In-Hospital Cardiac Arrest Secondary to Acute Pulmonary Embolism.

Crit Care Med 2018 03;46(3):e229-e234

Division of Critical Care Medicine, Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, PA.

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March 2018

Pulmonary Vasodilator Therapy in Shock-associated Cardiac Arrest.

Am J Respir Crit Care Med 2018 04;197(7):905-912

1 Department of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; and.

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April 2018

Functional and non-functional pancreatic neuroendocrine tumours: ENETS or AJCC TNM staging system?

Oncotarget 2017 Oct 7;8(47):82784-82795. Epub 2017 Aug 7.

National Institute for Health Research (NIHR) Liverpool Pancreas Biomedical Research Unit, Royal Liverpool University Hospital, University of Liverpool, Liverpool, UK.

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October 2017

Failure of Invasive Airway Placement on the First Attempt Is Associated With Progression to Cardiac Arrest in Pediatric Acute Respiratory Compromise.

Pediatr Crit Care Med 2018 01;19(1):9-16

Department of Pediatrics and Critical Care Medicine, Section of Pediatric Cardiac Intensive Care, Medical City Children's Hospital, Dallas, TX.

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January 2018

Systemic histone release disrupts plasmalemma and contributes to necrosis in acute pancreatitis.

Pancreatology 2017 Nov - Dec;17(6):884-892. Epub 2017 Oct 7.

NIHR Liverpool Pancreas Biomedical Research Unit, Royal Liverpool University Hospital, University of Liverpool, Liverpool, L69 3GA, UK.

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July 2018

The Future of Resuscitation: Personalized Physiology-Guided Cardiopulmonary Resuscitation.

Pediatr Crit Care Med 2017 11;18(11):1084-1086

Division of Critical Care Medicine, Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, PA.

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November 2017

Cardiopulmonary Resuscitation in Pediatric and Cardiac Intensive Care Units.

Pediatr Clin North Am 2017 10 18;64(5):961-972. Epub 2017 Aug 18.

Department of Anesthesia and Critical Care Medicine, University of Pennsylvania School of Medicine, Children's Hospital of Philadelphia, 3401 Civic Center Boulevard, Philadelphia, PA 19104, USA.

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October 2017

Dynamic monitoring of p53 translocation to mitochondria for the analysis of specific inhibitors using luciferase-fragment complementation.

Biotechnol Bioeng 2017 12 6;114(12):2818-2827. Epub 2017 Oct 6.

Department of Chemistry, School of Science, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.

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December 2017

Response to letter to the editor: Sepsis-associated in-hospital cardiac arrest.

J Crit Care 2017 08 21;40:291. Epub 2017 Jun 21.

The Children's Hospital of Philadelphia, Department of Anesthesiology and Critical Care Medicine, 34(th) Street & Civic Center Boulevard, Suite 8566, Philadelphia, PA 19104, USA. Electronic address:

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August 2017

Selective inhibition of BET proteins reduces pancreatic damage and systemic inflammation in bile acid- and fatty acid ethyl ester- but not caerulein-induced acute pancreatitis.

Pancreatology 2017 Sep - Oct;17(5):689-697. Epub 2017 Jun 10.

Department of Molecular and Clinical Cancer Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, UK; NIHR Liverpool Pancreas Biomedical Research Unit, Royal Liverpool University Hospital, Institute of Translational Medicine, University of Liverpool, Liverpool, UK. Electronic address:

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June 2018

Chai-Qin-Cheng-Qi Decoction and Carbachol Improve Intestinal Motility by Regulating Protein Kinase C-Mediated Ca Release in Colonic Smooth Muscle Cells in Rats with Acute Necrotising Pancreatitis.

Evid Based Complement Alternat Med 2017 26;2017:5864945. Epub 2017 Apr 26.

Department of Integrated Traditional Chinese and Western Medicine, Sichuan Provincial Pancreatitis Centre, West China Hospital, Sichuan University, Chengdu, China.

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April 2017

Synthesis of thioether andrographolide derivatives and their inhibitory effect against cancer cells.

Medchemcomm 2017 Jun 28;8(6):1268-1274. Epub 2017 Apr 28.

School of Chemical Engineering , Institute of Pharmaceutical Engineering Technology and Application , Key Laboratory of Green Chemistry of Sichuan Institutes of Higher Education , Sichuan University of Science & Engineering , Xueyuan Street 180, Huixing Road , Zigong , Sichuan 643000 , People's Republic of China . Email: ; Email: ; Tel: +86 813 5505601.

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June 2017

Sepsis-associated in-hospital cardiac arrest: Epidemiology, pathophysiology, and potential therapies.

J Crit Care 2017 08 31;40:128-135. Epub 2017 Mar 31.

The Children's Hospital of Philadelphia, Department of Anesthesiology and Critical Care Medicine, 34th Street & Civic Center Boulevard, Suite 8566, Philadelphia 19104, PA, USA. Electronic address:

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August 2017

Improved Retention of Chest Compression Psychomotor Skills With Brief "Rolling Refresher" Training.

Simul Healthc 2017 Aug;12(4):213-219

From the Center for Simulation, Advanced Education and Innovation (D.E.N., A.N., J.L., V.N.), Department of Anesthesiology and Critical Care Medicine (A.N., R.M.S., P.A.M., R.A.B., V.N.), Westat-Biostatistics and Data Management Core (O.U.E.), Department of Nursing, The Children's Hospital of Philadelphia (K.A.O), PA; and Norwegian National Advisory Unit for Prehospital Emergency Care (NAKOS) and Department of Anaesthesiology (J.K.-J.), Oslo University Hospital and University of Oslo, Oslo, Norway.

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August 2017

A hemodynamic-directed approach to pediatric cardiopulmonary resuscitation (HD-CPR) improves survival.

Resuscitation 2017 02 5;111:41-47. Epub 2016 Dec 5.

The Children's Hospital of Philadelphia, Department of Anesthesiology and Critical Care Medicine, 34th Street & Civic Center Boulevard, Philadelphia, PA 19104, United States.

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February 2017

Defining drug response for stratified medicine.

Drug Discov Today 2017 01 3;22(1):173-179. Epub 2016 Nov 3.

Wolfson Centre for Personalised Medicine, University of Liverpool, Liverpool L69 3GL, UK. Electronic address:

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January 2017

Blood Pressure- and Coronary Perfusion Pressure-Targeted Cardiopulmonary Resuscitation Improves 24-Hour Survival From Ventricular Fibrillation Cardiac Arrest.

Crit Care Med 2016 Nov;44(11):e1111-e1117

1Department of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA. 2Department of Pediatrics, St. Louis Children's Hospital, Washington University in St. Louis School of Medicine, St. Louis, MO. 3Department of Anesthesiology and Critical Care Medicine, Bloomberg Children's Center, Johns Hopkins Hospital, Johns Hopkins University School of Medicine, Baltimore, MD. 4Department of Emergency Medicine, The Hospital of the University of Pennsylvania, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

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November 2016

The authors reply.

Crit Care Med 2016 08;44(8):e762-4

Department of Anesthesia and Critical Care/Division of Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, PA; Department of Pediatrics/Division of Critical Care Medicine, University of Utah, Salt Lake City, UT; Department of Pediatrics/Division of Critical Care Medicine, Children's National Medical Center, Washington, DC.

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August 2016