Publications by authors named "Robert Sutton"

100Publications

Pediatric In-Hospital Cardiac Arrest and Cardiopulmonary Resuscitation in the United States: A Review.

Authors:
Ryan W Morgan Matthew P Kirschen Todd J Kilbaugh Robert M Sutton Alexis A Topjian

JAMA Pediatr 2020 Nov 23. Epub 2020 Nov 23.

Department of Anesthesiology and Critical Care Medicine, Division of Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

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November 2020

Portosystemic shunts versus endoscopic intervention with or without medical treatment for prevention of rebleeding in people with cirrhosis.

Authors:
Rosa G Simonetti Giovanni Perricone Helen L Robbins Narendra R Battula Martin O Weickert Robert Sutton Saboor Khan

Cochrane Database Syst Rev 2020 10 22;10:CD000553. Epub 2020 Oct 22.

Surgery, University Hosptial Coventry and Warwickshire, Coventry, UK.

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October 2020

Part 4: Pediatric Basic and Advanced Life Support 2020 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.

Authors:
Alexis A Topjian Tia T Raymond Dianne Atkins Melissa Chan Jonathan P Duff Benny L Joyner Javier J Lasa Eric J Lavonas Arielle Levy Melissa Mahgoub Garth D Meckler Kathryn E Roberts Robert M Sutton Stephen M Schexnayder

Pediatrics 2021 Jan 21;147(Suppl 1). Epub 2020 Oct 21.

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January 2021

Part 4: Pediatric Basic and Advanced Life Support: 2020 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.

Authors:
Alexis A Topjian Tia T Raymond Dianne Atkins Melissa Chan Jonathan P Duff Benny L Joyner Javier J Lasa Eric J Lavonas Arielle Levy Melissa Mahgoub Garth D Meckler Kathryn E Roberts Robert M Sutton Stephen M Schexnayder

Circulation 2020 Oct 21;142(16_suppl_2):S469-S523. Epub 2020 Oct 21.

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October 2020

Chaiqin chengqi decoction alleviates severity of acute pancreatitis via inhibition of TLR4 and NLRP3 inflammasome: Identification of bioactive ingredients via pharmacological sub-network analysis and experimental validation.

Authors:
Yongjian Wen Chenxia Han Tingting Liu Rui Wang Wenhao Cai Jingyu Yang Ge Liang Linbo Yao Na Shi Xianghui Fu Lihui Deng Robert Sutton John A Windsor Jiwon Hong Anthony R Phillips Dan Du Wei Huang Qing Xia

Phytomedicine 2020 Dec 1;79:153328. Epub 2020 Sep 1.

Department of Integrated Traditional Chinese and Western Medicine, Sichuan Provincial Pancreatitis Centre and West China-Liverpool Biomedical Research Centre, West China Hospital, Sichuan University, Chengdu 610041, China. Electronic address:

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December 2020

Epinephrine's effects on cerebrovascular and systemic hemodynamics during cardiopulmonary resuscitation.

Authors:
Constantine D Mavroudis Tiffany S Ko Ryan W Morgan Lindsay E Volk William P Landis Benjamin Smood Rui Xiao Marco Hefti Timothy W Boorady Alexandra Marquez Michael Karlsson Daniel J Licht Vinay M Nadkarni Robert A Berg Robert M Sutton Todd J Kilbaugh

Crit Care 2020 09 29;24(1):583. Epub 2020 Sep 29.

Department of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.

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September 2020

Critical thresholds: key to unlocking the door to the prevention and specific treatments for acute pancreatitis.

Authors:
Savio George Barreto Aida Habtezion Anna Gukovskaya Aurelia Lugea Christie Jeon Dhiraj Yadav Peter Hegyi Viktória Venglovecz Robert Sutton Stephen J Pandol

Gut 2021 Jan 24;70(1):194-203. Epub 2020 Sep 24.

Division of Digestive and Liver Diseases, Cedars-Sinai Medical Center, Los Angeles, California, USA

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January 2021

Hemoconcentration is associated with early faster fluid rate and increased risk of persistent organ failure in acute pancreatitis patients.

Authors:
Tao Jin Lan Li Lihui Deng Si Wen Ruwen Zhang Na Shi Ping Zhu Lan Lan Ziqi Lin Kun Jiang Jia Guo Tingting Liu Anthony Philips Xiaonan Yang Vikesh K Singh Robert Sutton John A Windsor Wei Huang Qing Xia

JGH Open 2020 Aug 13;4(4):684-691. Epub 2020 Mar 13.

Department and Laboratory of Integrated Traditional Chinese and Western Medicine, Sichuan Provincial Pancreatitis Centre and West China-Liverpool Biomedical Research Centre, West China Hospital Sichuan University Chengdu China.

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August 2020

Cold Debriefings after In-hospital Cardiac Arrest in an International Pediatric Resuscitation Quality Improvement Collaborative.

Authors:
Heather A Wolfe Jesse Wenger Robert Sutton Roopa Seshadri Dana E Niles Vinay Nadkarni Jordan Duval-Arnould Anita I Sen Adam Cheng

Pediatr Qual Saf 2020 Jul-Aug;5(4):e319. Epub 2020 Jul 8.

Alberta Children's Hospital, University of Calgary.

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July 2020

eStablish And Formalize Expert Criteria for Avoidable Resuscitation Review (SAFECARR) Electronic Delphi: Development of a Consensus Framework for Classifying and Reviewing Cardiac Arrests Within the PICU.

Authors:
Maya Dewan Amanda O'Halloran Monica Kleinman Ken Tegtmeyer Regan Gallagher Vinay Nadkarni Robert M Sutton Heather A Wolfe

Pediatr Crit Care Med 2020 11;21(11):992-999

Department of Anesthesiology and Critical Care, The Children's Hospital of Philadelphia, Philadelphia, PA.

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November 2020

Deployment of a Clinical Pathway to Improve Postcardiac Arrest Care: A Before-After Study.

Authors:
Jessica C Fowler Heather A Wolfe Rui Xiao Sitara P Kumar Jane E Whitney Larissa Hutchins Robert M Sutton Vinay M Nadkarni Robert A Berg Alexis A Topjian

Pediatr Crit Care Med 2020 10;21(10):e898-e907

Division of Pediatric Critical Care Medicine, Department of Anesthesiology and Critical Care, Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.

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October 2020

Association between time of day and CPR quality as measured by CPR hemodynamics during pediatric in-hospital CPR.

Authors:
Heather A Wolfe Ryan W Morgan Robert M Sutton Ron W Reeder Kathleen L Meert Murray M Pollack Andrew R Yates John T Berger Christopher J Newth Joseph A Carcillo Patrick S McQuillen Rick E Harrison Frank W Moler Todd C Carpenter Daniel A Notterman J Michael Dean Vinay M Nadkarni Robert A Berg

Resuscitation 2020 08 1;153:209-216. Epub 2020 Jul 1.

Department of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA, United States.

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August 2020

Pediatric Resuscitation Practices During the Coronavirus Disease 2019 Pandemic.

Authors:
Ryan W Morgan Martha Kienzle Anita I Sen Todd J Kilbaugh Maya Dewan Tia T Raymond Adam S Himebauch Robert A Berg Ken Tegtmeyer Vinay M Nadkarni Alexis A Topjian Robert M Sutton Heather A Wolfe

Pediatr Crit Care Med 2020 09;21(9):e651-e660

Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.

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September 2020

Knockout of the Mitochondrial Calcium Uniporter Strongly Suppresses Stimulus-Metabolism Coupling in Pancreatic Acinar Cells but Does Not Reduce Severity of Experimental Acute Pancreatitis.

Authors:
Michael Chvanov Svetlana Voronina Xiaoying Zhang Svetlana Telnova Robert Chard Yulin Ouyang Jane Armstrong Helen Tanton Muhammad Awais Diane Latawiec Robert Sutton David N Criddle Alexei V Tepikin

Cells 2020 06 5;9(6). Epub 2020 Jun 5.

Department of Cellular and Molecular Physiology, University of Liverpool, Liverpool L69 3BX, UK.

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June 2020

Factors affecting the course of resuscitation from cardiac arrest with pulseless electrical activity in children and adolescents.

Authors:
Eirik Skogvoll Trond Nordseth Robert M Sutton Trygve Eftestøl Unai Irusta Elisabete Aramendi Dana Niles Vinay Nadkarni Robert A Berg Benjamin S Abella Jan Terje Kvaløy

Resuscitation 2020 07 17;152:116-122. Epub 2020 May 17.

Department of Mathematics and Physics, University of Stavanger, Norway.

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July 2020

Pediatric cardiopulmonary resuscitation quality during intra-hospital transport.

Authors:
Morgann Loaec Adam S Himebauch Todd J Kilbaugh Robert A Berg Kathryn Graham Richard Hanna Heather A Wolfe Robert M Sutton Ryan W Morgan

Resuscitation 2020 07 15;152:123-130. Epub 2020 May 15.

Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, 3401 Civic Center Boulevard, Philadelphia, PA 19104, United States. Electronic address:

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July 2020

Interim Guidance for Basic and Advanced Life Support in Children and Neonates With Suspected or Confirmed COVID-19.

Authors:
Alexis Topjian Khalid Aziz Beena D Kamath-Rayne Dianne L Atkins Lance Becker Robert A Berg Steven M Bradley Farhan Bhanji Steven Brooks Melissa Chan Paul Chan Adam Cheng Allan de Caen Jonathan P Duff Marilyn Escobedo Gustavo E Flores Susan Fuchs Saket Girotra Antony Hsu Benny L Joyner Monica Kleinman Javier J Lasa Henry C Lee Rebecca E Lehotzky Arielle Levy Mary E Mancini Mary E McBride Garth Meckler Raina M Merchant Ryan W Morgan Vinay Nadkarni Ashish R Panchal Mary Ann Peberdy Tia Raymond Kathryn Roberts Comilla Sasson Stephen M Schexnayder Robert M Sutton Mark Terry Brian Walsh David S Wang Carolyn M Zelop Dana P Edelson

Pediatrics 2020 May 4. Epub 2020 May 4.

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May 2020

Parenchymal pressure injury Ca entry mechanism in pancreatitis.

Authors:
Robert Sutton

Cell Calcium 2020 Apr 19;88:102208. Epub 2020 Apr 19.

Liverpool Pancreatitis Research Group, Institute of Translational Medicine, University of Liverpool and Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK. Electronic address:

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April 2020

Oxygen Exposure During Cardiopulmonary Resuscitation Is Associated With Cerebral Oxidative Injury in a Randomized, Blinded, Controlled, Preclinical Trial.

Authors:
Alexandra M Marquez Ryan W Morgan Tiffany Ko William P Landis Marco M Hefti Constantine D Mavroudis Meagan J McManus Michael Karlsson Jonathan Starr Anna L Roberts Yuxi Lin Vinay Nadkarni Daniel J Licht Robert A Berg Robert M Sutton Todd J Kilbaugh

J Am Heart Assoc 2020 05 23;9(9):e015032. Epub 2020 Apr 23.

Division of Critical Care Medicine Department of Anesthesiology and Critical Care Medicine Children's Hospital of Philadelphia PA.

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May 2020

Aqueous extraction from dachengqi formula granules reduces the severity of mouse acute pancreatitis via inhibition of pancreatic pro-inflammatory signalling pathways.

Authors:
Xiaohua Ma Tao Jin Chenxia Han Na Shi Ge Liang Yongjian Wen Jingyu Yang Xianghui Fu Tian Lan Kun Jiang Quentin M Nunes Michael Chvanov David N Criddle Anthony R Philips Lihui Deng Tingting Liu John A Windsor Robert Sutton Dan Du Wei Huang Qing Xia

J Ethnopharmacol 2020 Jul 18;257:112861. Epub 2020 Apr 18.

Department of Integrated Traditional Chinese and Western Medicine, Sichuan Provincial Pancreatitis Centre and West China-Liverpool Biomedical Research Centre, West China Hospital, Sichuan University, Chengdu, 610041, China. Electronic address:

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July 2020

Survival and Hemodynamics During Pediatric Cardiopulmonary Resuscitation for Bradycardia and Poor Perfusion Versus Pulseless Cardiac Arrest.

Authors:
Ryan W Morgan Ron W Reeder Kathleen L Meert Russell Telford Andrew R Yates John T Berger Kathryn Graham William P Landis Todd J Kilbaugh Christopher J Newth Joseph A Carcillo Patrick S McQuillen Rick E Harrison Frank W Moler Murray M Pollack Todd C Carpenter Daniel Notterman Richard Holubkov J Michael Dean Vinay M Nadkarni Robert A Berg Robert M Sutton

Crit Care Med 2020 06;48(6):881-889

Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia & University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

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June 2020

Providing Early Attending Physician Expertise via Telemedicine to Improve Rapid Response Team Evaluations.

Authors:
Marie L Fiero Samuel Rosenblatt Bingqing Zhang Megan Snyder Margaret A Priestley John Chuo Kate Fuller Janell Mensinger Christopher P Bonafide Robert M Sutton

Pediatr Crit Care Med 2020 05;21(5):e221-e227

Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

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May 2020

Improving Small Intestinal Motility in Experimental Acute Necrotising Pancreatitis by Modulating the CPI-17/MLCP Pathway Using Chaiqin Chengqi Decoction.

Authors:
Ziqi Lin Chenlong Zhang Xiaoxin Zhang Na Shi Yongjian Wen Chengxia Han Dan Du Tingting Liu Tao Jin Lihui Deng Kun Jiang Xiaonan Yang Jia Guo Anthony Philips Robert Sutton John A Windsor Wei Huang Ping Xue Qing Xia

Evid Based Complement Alternat Med 2020 10;2020:9189457. Epub 2020 Feb 10.

Department of Integrated Traditional Chinese and Western Medicine, Sichuan Provincial Pancreatitis Centre and West China-Liverpool Biomedical Research Centre, West China Hospital, Sichuan University, Chengdu, China.

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February 2020

Variability in chest compression rate calculations during pediatric cardiopulmonary resuscitation.

Authors:
William P Landis Ryan W Morgan Ron W Reeder Kathryn Graham Ashley Siems J Wesley Diddle Murray M Pollack Tensing Maa Richard P Fernandez Andrew R Yates Bradley Tilford Tageldin Ahmed Kathleen L Meert Carleen Schneiter Robert Bishop Peter M Mourani Maryam Y Naim Stuart Friess Candice Burns Arushi Manga Deborah Franzon Sarah Tabbutt Patrick S McQuillen Christopher M Horvat Matthew Bochkoris Joseph A Carcillo Leanna Huard Myke Federman Anil Sapru Shirley Viteri David A Hehir Daniel A Notterman Richard Holubkov J Michael Dean Vinay M Nadkarni Robert A Berg Heather A Wolfe Robert M Sutton

Resuscitation 2020 04 20;149:127-133. Epub 2020 Feb 20.

Department of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA, United States.

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April 2020

Deviations from AHA guidelines during pediatric cardiopulmonary resuscitation are associated with decreased event survival.

Authors:
Heather A Wolfe Ryan W Morgan Bingqing Zhang Alexis A Topjian Ericka L Fink Robert A Berg Vinay M Nadkarni Akira Nishisaki Janell Mensinger Robert M Sutton

Resuscitation 2020 04 11;149:89-99. Epub 2020 Feb 11.

Department of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.

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April 2020

The authors reply.

Authors:
Ryan W Morgan Robert A Berg Robert M Sutton

Crit Care Med 2020 02;48(2):e160-e161

Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia & University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

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February 2020

Early Rapid Fluid Therapy Is Associated with Increased Rate of Noninvasive Positive-Pressure Ventilation in Hemoconcentrated Patients with Severe Acute Pancreatitis.

Authors:
Lan Li Tao Jin Si Wen Na Shi Ruwen Zhang Ping Zhu Ziqi Lin Kun Jiang Jia Guo Tingting Liu Anthony Philips Lihui Deng Xiaonan Yang Vikesh K Singh Robert Sutton John A Windsor Wei Huang Qing Xia

Dig Dis Sci 2020 09 7;65(9):2700-2711. Epub 2020 Jan 7.

Department and Laboratory of Integrated Traditional Chinese and Western Medicine, Sichuan Provincial Pancreatitis Center and West China-Liverpool Biomedical Research Center, West China Hospital, Sichuan University, No. 37 Wannan Guoxue Alley, Chengdu, 610041, Sichuan Province, China.

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September 2020

Altered Bioenergetics of Blood Cell Sub-Populations in Acute Pancreatitis Patients.

Authors:
Jack C Morton Jane A Armstrong Ajay Sud Alexei V Tepikin Robert Sutton David N Criddle

J Clin Med 2019 Dec 13;8(12). Epub 2019 Dec 13.

Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool L69 3BX, UK.

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December 2019

2019 American Heart Association Focused Update on Pediatric Basic Life Support: An Update to the American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.

Authors:
Jonathan P Duff Alexis A Topjian Marc D Berg Melissa Chan Sarah E Haskell Benny L Joyner Javier J Lasa S Jill Ley Tia T Raymond Robert Michael Sutton Mary Fran Hazinski Dianne L Atkins

Pediatrics 2020 01 14;145(1). Epub 2019 Nov 14.

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January 2020

2019 American Heart Association Focused Update on Pediatric Advanced Life Support: An Update to the American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.

Authors:
Jonathan P Duff Alexis A Topjian Marc D Berg Melissa Chan Sarah E Haskell Benny L Joyner Javier J Lasa S Jill Ley Tia T Raymond Robert Michael Sutton Mary Fran Hazinski Dianne L Atkins

Pediatrics 2020 01 14;145(1). Epub 2019 Nov 14.

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January 2020

2019 American Heart Association Focused Update on Pediatric Advanced Life Support: An Update to the American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.

Authors:
Jonathan P Duff Alexis A Topjian Marc D Berg Melissa Chan Sarah E Haskell Benny L Joyner Javier J Lasa S Jill Ley Tia T Raymond Robert Michael Sutton Mary Fran Hazinski Dianne L Atkins

Circulation 2019 12 14;140(24):e904-e914. Epub 2019 Nov 14.

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December 2019

2019 American Heart Association Focused Update on Pediatric Basic Life Support: An Update to the American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.

Authors:
Jonathan P Duff Alexis A Topjian Marc D Berg Melissa Chan Sarah E Haskell Benny L Joyner Javier J Lasa S Jill Ley Tia T Raymond Robert Michael Sutton Mary Fran Hazinski Dianne L Atkins

Circulation 2019 12 14;140(24):e915-e921. Epub 2019 Nov 14.

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December 2019

Prevalence and Outcomes of Pediatric In-Hospital Cardiac Arrest Associated With Pulmonary Hypertension.

Authors:
Ryan W Morgan Alexis A Topjian Yan Wang Natalie J Atkin Todd J Kilbaugh Francis X McGowan Robert A Berg Laura Mercer-Rosa Robert M Sutton Adam S Himebauch

Pediatr Crit Care Med 2020 04;21(4):305-313

Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.

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April 2020

LAP-like non-canonical autophagy and evolution of endocytic vacuoles in pancreatic acinar cells.

Authors:
Francesca De Faveri Michael Chvanov Svetlana Voronina Danielle Moore Liam Pollock Lee Haynes Muhammad Awais Alison J Beckett Ulrike Mayer Robert Sutton David N Criddle Ian A Prior Tom Wileman Alexei V Tepikin

Autophagy 2020 07 25;16(7):1314-1331. Epub 2019 Oct 25.

Department of Cellular and Molecular Physiology, University of Liverpool , Liverpool, UK.

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July 2020

Performance of a Clinical Decision Support Tool to Identify PICU Patients at High Risk for Clinical Deterioration.

Authors:
Maya Dewan Naveen Muthu Eric Shelov Christopher P Bonafide Patrick Brady Daniela Davis Eric S Kirkendall Dana Niles Robert M Sutton Danielle Traynor Ken Tegtmeyer Vinay Nadkarni Heather Wolfe

Pediatr Crit Care Med 2020 02;21(2):129-135

Department of Anesthesiology and Critical Care Medicine, Division of Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA.

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February 2020

Survival and Cardiopulmonary Resuscitation Hemodynamics Following Cardiac Arrest in Children With Surgical Compared to Medical Heart Disease.

Authors:
Andrew R Yates Robert M Sutton Ron W Reeder Kathleen L Meert John T Berger Richard Fernandez David Wessel Christopher J Newth Joseph A Carcillo Patrick S McQuillen Rick E Harrison Frank W Moler Murray M Pollack Todd C Carpenter Daniel A Notterman J Michael Dean Vinay M Nadkarni Robert A Berg

Pediatr Crit Care Med 2019 12;20(12):1126-1136

Department of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA.

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December 2019

Simulating blood pressure and end tidal CO2 in a CPR training manikin.

Authors:
Nicholas Widmann Robert Sutton Newton Buchanan Dana E Niles Godfrey Nazareth Vinay Nadkarni Matthew R Maltese

Comput Methods Programs Biomed 2019 Oct 3;180:105009. Epub 2019 Aug 3.

Department of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, 34th Street and Civic Center Blvd Philadelphia, PA 19104, USA; The Perelman School of Medicine, University of Pennsylvania, 3400 Civic Center Blvd, Philadelphia, PA 19104, USA. Electronic address:

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October 2019

Pancreas-specific plasma amylase for assessment and diagnosis of chronic pancreatitis: New insights on an old topic.

Authors:
Søren Schou Olesen Henrik Krarup Jakob Lykke Poulsen Jeppe Hagstrup Christensen Andrea Rhiannon Glynne Sheel Robert Sutton William Greenhalf Christopher Halloran Asbjørn Mohr Drewes

United European Gastroenterol J 2019 08 16;7(7):955-964. Epub 2019 Apr 16.

Centre for Pancreatic Diseases, Department of Gastroenterology and Hepatology, Aalborg University Hospital, Aalborg, Denmark.

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August 2019

Functional outcomes among survivors of pediatric in-hospital cardiac arrest are associated with baseline neurologic and functional status, but not with diastolic blood pressure during CPR.

Authors:
Heather A Wolfe Robert M Sutton Ron W Reeder Kathleen L Meert Murray M Pollack Andrew R Yates John T Berger Christopher J Newth Joseph A Carcillo Patrick S McQuillen Rick E Harrison Frank W Moler Todd C Carpenter Daniel A Notterman Richard Holubkov J Michael Dean Vinay M Nadkarni Robert A Berg

Resuscitation 2019 10 9;143:57-65. Epub 2019 Aug 9.

Department of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA United States.

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October 2019

Ventilation Rates and Pediatric In-Hospital Cardiac Arrest Survival Outcomes.

Authors:
Robert M Sutton Ron W Reeder William P Landis Kathleen L Meert Andrew R Yates Ryan W Morgan John T Berger Christopher J Newth Joseph A Carcillo Patrick S McQuillen Rick E Harrison Frank W Moler Murray M Pollack Todd C Carpenter Daniel A Notterman Richard Holubkov J Michael Dean Vinay M Nadkarni Robert A Berg

Crit Care Med 2019 11;47(11):1627-1636

Department of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA.

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November 2019

Matched Retrospective Cohort Study of Thiamine to Treat Persistent Hyperlactatemia in Pediatric Septic Shock.

Authors:
Scott L Weiss Bridget Blowey Luke Keele Rebecca Ganetzky Chaya N Murali Julie C Fitzgerald Robert M Sutton Robert A Berg

Pediatr Crit Care Med 2019 09;20(9):e452-e456

Department of Anesthesiology and Critical Care, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

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September 2019

Duration of organ failure impacts mortality in acute pancreatitis.

Authors:
Na Shi Tingting Liu Daniel de la Iglesia-Garcia Lihui Deng Tao Jin Lan Lan Ping Zhu Weiming Hu Zongguang Zhou Vikesh Singh J Enrique Dominguez-Munoz John Windsor Wei Huang Qing Xia Robert Sutton

Gut 2020 03 11;69(3):604-605. Epub 2019 Feb 11.

Liverpool Pancreatitis Study Group, Royal Liverpool University Hospital and Institute of Translational Medicine, University of Liverpool, Liverpool, UK.

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March 2020

Cardiopulmonary Resuscitation in the Pediatric Cardiac Catheterization Laboratory: A Report From the American Heart Association's Get With the Guidelines-Resuscitation Registry.

Authors:
Javier J Lasa Alexander Alali Charles G Minard Dhaval Parekh Shelby Kutty Michael Gaies Tia T Raymond Anne-Marie Guerguerian Dianne Atkins Elizabeth Foglia Ericka Fink Joan Roberts Jordan Duval-Arnould Melanie Bembea Monica Kleinman Punkaj Gupta Robert Sutton Taylor Sawyer

Pediatr Crit Care Med 2019 11;20(11):1040-1047

Section of Pediatric Cardiac Intensive Care, Medical City Children's Hospital, Dallas, TX.

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November 2019

The heparin-binding proteome in normal pancreas and murine experimental acute pancreatitis.

Authors:
Quentin M Nunes Dunhao Su Philip J Brownridge Deborah M Simpson Changye Sun Yong Li Thao P Bui Xiaoying Zhang Wei Huang Daniel J Rigden Robert J Beynon Robert Sutton David G Fernig

PLoS One 2019 18;14(6):e0217633. Epub 2019 Jun 18.

Liverpool Pancreatitis Research Group, Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, United Kingdom.

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February 2020

The association of immediate post cardiac arrest diastolic hypertension and survival following pediatric cardiac arrest.

Authors:
Alexis A Topjian Robert M Sutton Ron W Reeder Russell Telford Kathleen L Meert Andrew R Yates Ryan W Morgan John T Berger Christopher J Newth Joseph A Carcillo Patrick S McQuillen Rick E Harrison Frank W Moler Murray M Pollack Todd C Carpenter Daniel A Notterman Richard Holubkov J Michael Dean Vinay M Nadkarni Robert A Berg Athena F Zuppa Katherine Graham Carolann Twelves Mary Ann Diliberto William P Landis Elyse Tomanio Jeni Kwok Michael J Bell Alan Abraham Anil Sapru Mustafa F Alkhouli Sabrina Heidemann Ann Pawluszka Mark W Hall Lisa Steele Thomas P Shanley Monica Weber Heidi J Dalton Aimee La Bell Peter M Mourani Kathryn Malone Christopher Locandro Whitney Coleman Alecia Peterson Julie Thelen Allan Doctor

Resuscitation 2019 08 6;141:88-95. Epub 2019 Jun 6.

Department of Pediatrics, Washington University School of Medicine, St. Louis, MO, United States.

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August 2019

Exocrine Pancreatic Insufficiency Following Acute Pancreatitis: Systematic Review and Meta-Analysis.

Authors:
Wei Huang Daniel de la Iglesia-García Iria Baston-Rey Cristina Calviño-Suarez Jose Lariño-Noia Julio Iglesias-Garcia Na Shi Xiaoying Zhang Wenhao Cai Lihui Deng Danielle Moore Vikesh K Singh Qing Xia John A Windsor J Enrique Domínguez-Muñoz Robert Sutton

Dig Dis Sci 2019 07 4;64(7):1985-2005. Epub 2019 Jun 4.

Liverpool Pancreatitis Research Group, Royal Liverpool University Hospital, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.

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July 2019

Antibiotic therapy in acute pancreatitis: From global overuse to evidence based recommendations.

Authors:
Andrea Párniczky Tamás Lantos Eszter Margit Tóth Zsolt Szakács Szilárd Gódi Roland Hágendorn Dóra Illés Balázs Koncz Katalin Márta Alexandra Mikó Dóra Mosztbacher Balázs Csaba Németh Dániel Pécsi Anikó Szabó Ákos Szücs Péter Varjú Andrea Szentesi Erika Darvasi Bálint Erőss Ferenc Izbéki László Gajdán Adrienn Halász Áron Vincze Imre Szabó Gabriella Pár Judit Bajor Patrícia Sarlós József Czimmer József Hamvas Tamás Takács Zoltán Szepes László Czakó Márta Varga János Novák Barnabás Bod Attila Szepes János Sümegi Mária Papp Csaba Góg Imola Török Wei Huang Qing Xia Ping Xue Weiqin Li Weiwei Chen Natalia V Shirinskaya Vladimir L Poluektov Anna V Shirinskaya Péter Jenő Hegyi Marian Bátovský Juan Armando Rodriguez-Oballe Isabel Miguel Salas Javier Lopez-Diaz J Enrique Dominguez-Munoz Xavier Molero Elizabeth Pando María Lourdes Ruiz-Rebollo Beatriz Burgueño-Gómez Yu-Ting Chang Ming-Chu Chang Ajay Sud Danielle Moore Robert Sutton Amir Gougol Georgios I Papachristou Yaroslav Mykhailovych Susak Illia Olehovych Tiuliukin António Pedro Gomes Maria Jesus Oliveira David João Aparício Marcel Tantau Floreta Kurti Mila Kovacheva-Slavova Stephanie-Susanne Stecher Julia Mayerle Goran Poropat Kshaunish Das Marco Vito Marino Gabriele Capurso Ewa Małecka-Panas Hubert Zatorski Anita Gasiorowska Natalia Fabisiak Piotr Ceranowicz Beata Kuśnierz-Cabala Joana Rita Carvalho Samuel Raimundo Fernandes Jae Hyuck Chang Eun Kwang Choi Jimin Han Sara Bertilsson Hanaz Jumaa Gabriel Sandblom Sabite Kacar Minas Baltatzis Aliaksandr Vladimir Varabei Vizhynis Yeshy Serge Chooklin Andriy Kozachenko Nikolay Veligotsky Péter Hegyi

Pancreatology 2019 Jun 19;19(4):488-499. Epub 2019 Apr 19.

Institute for Translational Medicine, Szentágothai Research Centre, Medical School, University of Pécs, Pécs, Hungary; First Department of Medicine, Faculty of Medicine, University of Szeged, Szeged, Hungary; Division of Translational Medicine, First Department of Medicine, Medical School, University of Pécs, Pécs, Hungary; Hungarian Academy of Sciences-University of Szeged, Momentum Gastroenterology Multidisciplinary Research Group, Szeged, Hungary. Electronic address:

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June 2019

Mitochondrial Targeting of Antioxidants Alters Pancreatic Acinar Cell Bioenergetics and Determines Cell Fate.

Authors:
Jane A Armstrong Nicole J Cash Jack C Morton Alexei V Tepikin Robert Sutton David N Criddle

Int J Mol Sci 2019 Apr 5;20(7). Epub 2019 Apr 5.

Department of Cellular & Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool L69 3BX, UK.

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April 2019

Hemodynamic effects of chest compression interruptions during pediatric in-hospital cardiopulmonary resuscitation.

Authors:
Ryan W Morgan William P Landis Alexandra Marquez Kathryn Graham Anna L Roberts Kasper G Lauridsen Heather A Wolfe Vinay M Nadkarni Alexis A Topjian Robert A Berg Todd J Kilbaugh Robert M Sutton

Resuscitation 2019 06 1;139:1-8. Epub 2019 Apr 1.

The Children's Hospital of Philadelphia, Department of Anesthesiology and Critical Care Medicine, 3401 Civic Center Blvd, Philadelphia, PA 19104, United States.

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June 2019

Hypertriglyceridaemia-associated acute pancreatitis: diagnosis and impact on severity.

Authors:
Ruwen Zhang Lihui Deng Tao Jin Ping Zhu Na Shi Kun Jiang Lan Li Xinmin Yang Jia Guo Xiaonan Yang Tingting Liu Rajarshi Mukherjee Vikesh K Singh John A Windsor Robert Sutton Wei Huang Qing Xia

HPB (Oxford) 2019 09 15;21(9):1240-1249. Epub 2019 Mar 15.

Department of Integrated Traditional Chinese and Western Medicine, Sichuan Provincial Pancreatitis Centre and West China-Liverpool Biomedical Research Centre, West China Hospital of Sichuan University, Chengdu, China. Electronic address:

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September 2019

Hemodynamic-Directed Cardiopulmonary Resuscitation Improves Neurologic Outcomes and Mitochondrial Function in the Heart and Brain.

Authors:
Andrew J Lautz Ryan W Morgan Michael Karlsson Constantine D Mavroudis Tiffany S Ko Daniel J Licht Vinay M Nadkarni Robert A Berg Robert M Sutton Todd J Kilbaugh

Crit Care Med 2019 03;47(3):e241-e249

Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

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March 2019

Mechanisms of Pancreatic Injury Induced by Basic Amino Acids Differ Between L-Arginine, L-Ornithine, and L-Histidine.

Authors:
Xiaoying Zhang Tao Jin Na Shi Linbo Yao Xinmin Yang Chenxia Han Li Wen Dan Du Peter Szatmary Rajarshi Mukherjee Tingting Liu Qing Xia David N Criddle Wei Huang Michael Chvanov Robert Sutton

Front Physiol 2018 15;9:1922. Epub 2019 Jan 15.

Liverpool Pancreatitis Study Group, Royal Liverpool University Hospital, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom.

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January 2019

Rhythm characteristics and patterns of change during cardiopulmonary resuscitation for in-hospital paediatric cardiac arrest.

Authors:
Trond Nordseth Dana E Niles Trygve Eftestøl Robert M Sutton Unai Irusta Benjamin S Abella Robert A Berg Vinay M Nadkarni Eirik Skogvoll

Resuscitation 2019 02 9;135:45-50. Epub 2019 Jan 9.

Department of Circulation and Medical Imaging, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, NO-7491, Trondheim, Norway; Department of Anaesthesia and Intensive Care Medicine, St.Olav Hospital, Trondheim, Norway.

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February 2019

Ethyl pyruvate and analogs as potential treatments for acute pancreatitis: A review of in vitro and in vivo studies.

Authors:
Linbo Yao Chunru Cheng Xinmin Yang Chenxia Han Dan Du Tingting Liu Michael Chvanov John Windsor Robert Sutton Wei Huang Qing Xia

Pancreatology 2019 Mar 25;19(2):209-216. Epub 2018 Dec 25.

Department of Integrated Traditional Chinese and Western Medicine, Sichuan Provincial Pancreatitis Centre and West China-Liverpool Biomedical Research Centre, West China Hospital, Sichuan University, Chengdu 610041, China. Electronic address:

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March 2019

Response by Berg et al to Letter Regarding Article, "Association Between Diastolic Blood Pressure During Pediatric In-Hospital Cardiopulmonary Resuscitation and Survival".

Authors:
Robert A Berg Vinay M Nadkarni Robert M Sutton

Circulation 2018 11;138(22):2588-2589

Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine.

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November 2018

2018 American Heart Association Focused Update on Pediatric Advanced Life Support: An Update to the American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.

Authors:
Jonathan P Duff Alexis Topjian Marc D Berg Melissa Chan Sarah E Haskell Benny L Joyner Javier J Lasa Sondra J Ley Tia T Raymond Robert M Sutton Mary Fran Hazinski Dianne L Atkins

Circulation 2018 12;138(23):e731-e739

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December 2018

Accelerating the Drug Delivery Pipeline for Acute and Chronic Pancreatitis-Knowledge Gaps and Research Opportunities: Overview Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop.

Authors:
Aliye Uc Dana K Andersen Drucy Borowitz Marshall J Glesby Julia Mayerle Robert Sutton Stephen J Pandol

Pancreas 2018 Nov/Dec;47(10):1180-1184

Division of Digestive and Liver Diseases, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA.

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March 2019

A systematic review and meta-analysis of metal versus plastic stents for drainage of pancreatic fluid collections: metal stents are advantageous.

Authors:
Rebecca Saunders Jayapal Ramesh Silvia Cicconi Jonathan Evans Vincent S Yip Michael Raraty Paula Ghaneh Robert Sutton John P Neoptolemos Christopher Halloran

Surg Endosc 2019 05 6;33(5):1412-1425. Epub 2018 Sep 6.

Institute of Translational Medicine, University of Liverpool, Liverpool, UK.

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May 2019

Response and outcome from fluid resuscitation in acute pancreatitis: a prospective cohort study.

Authors:
Tao Jin Kun Jiang Lihui Deng Jia Guo Yuwan Wu Zhengyan Wang Na Shi Xiaoxin Zhang Ziqi Lin Varsha Asrani Peter Jones Anubhav Mittal Anthony Phillips Robert Sutton Wei Huang Xiaonan Yang Qing Xia John A Windsor

HPB (Oxford) 2018 11 29;20(11):1082-1091. Epub 2018 Aug 29.

Department of Surgery, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.

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November 2018

RCAN1 is a marker of oxidative stress, induced in acute pancreatitis.

Authors:
K Jessica Norberg Salvatore Nania Xuan Li Hui Gao Peter Szatmary Ralf Segersvärd Stephan Haas Annika Wagman Urban Arnelo Robert Sutton Rainer L Heuchel J Matthias Löhr

Pancreatology 2018 Oct 16;18(7):734-741. Epub 2018 Aug 16.

Pancreas Cancer Research Lab, Dept. of Clinical Intervention and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden; Centre for Digestive Diseases, Karolinska University Hospital, Stockholm, Sweden. Electronic address:

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October 2018

The diagnostic value of Rosemont and Japanese diagnostic criteria for 'indeterminate', 'suggestive', 'possible' and 'early' chronic pancreatitis.

Authors:
Andrea R G Sheel Ryan D Baron Ioannis Sarantitis Jayapal Ramesh Paula Ghaneh Michael G T Raraty Vincent Yip Robert Sutton Michael R Goulden Fiona Campbell Ammad Farooq Priya Healey Richard Jackson Christopher M Halloran John P Neoptolemos

Pancreatology 2018 Oct 7;18(7):774-784. Epub 2018 Aug 7.

Department of Surgery, University of Heidelberg, Heidelberg, Germany.

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October 2018

End-tidal carbon dioxide during pediatric in-hospital cardiopulmonary resuscitation.

Authors:
Robert A Berg Ron W Reeder Kathleen L Meert Andrew R Yates John T Berger Christopher J Newth Joseph A Carcillo Patrick S McQuillen Rick E Harrison Frank W Moler Murray M Pollack Todd C Carpenter Daniel A Notterman Richard Holubkov J Michael Dean Vinay M Nadkarni Robert M Sutton

Resuscitation 2018 12 15;133:173-179. Epub 2018 Aug 15.

Department of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, University of Pennsylvania, 3400 Civic Center Blvd, Philadelphia, PA 19104, United States.

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December 2018

Biology, role and therapeutic potential of circulating histones in acute inflammatory disorders.

Authors:
Peter Szatmary Wei Huang David Criddle Alexei Tepikin Robert Sutton

J Cell Mol Med 2018 10 7;22(10):4617-4629. Epub 2018 Aug 7.

Liverpool Pancreatitis Research Group, Royal Liverpool University Hospital and Institute of Translational Medicine, University of Liverpool, Liverpool, UK.

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October 2018

FF-ATP Synthase Inhibitory Factor 1 in the Normal Pancreas and in Pancreatic Ductal Adenocarcinoma: Effects on Bioenergetics, Invasion and Proliferation.

Authors:
Helen Tanton Svetlana Voronina Anthony Evans Jane Armstrong Robert Sutton David N Criddle Lee Haynes Michael C Schmid Fiona Campbell Eithne Costello Alexei V Tepikin

Front Physiol 2018 11;9:833. Epub 2018 Jul 11.

Department of Cellular and Molecular Physiology, University of Liverpool, Liverpool, United Kingdom.

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July 2018

Chest compression rates and pediatric in-hospital cardiac arrest survival outcomes.

Authors:
Robert M Sutton Ron W Reeder William Landis Kathleen L Meert Andrew R Yates John T Berger Christopher J Newth Joseph A Carcillo Patrick S McQuillen Rick E Harrison Frank W Moler Murray M Pollack Todd C Carpenter Daniel A Notterman Richard Holubkov J Michael Dean Vinay M Nadkarni Robert A Berg

Resuscitation 2018 09 18;130:159-166. Epub 2018 Jul 18.

Department of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA, USA.

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September 2018

Acute parotitis due to MRSA causing Lemierre's syndrome.

Authors:
Edward Alabraba Nichola Manu Gemma Fairclough Robert Sutton

Oxf Med Case Reports 2018 May 31;2018(5):omx056. Epub 2018 May 31.

Liverpool NIHR Pancreas Biomedical Research Unit, Royal Liverpool University Hospital, University of Liverpool, Liverpool L69 3GA, UK.

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May 2018

Protective effects of flavonoids from Coreopsis tinctoria Nutt. on experimental acute pancreatitis via Nrf-2/ARE-mediated antioxidant pathways.

Authors:
Dan Du Linbo Yao Rui Zhang Na Shi Yan Shen Xinmin Yang Xiaoying Zhang Tao Jin Tingting Liu Liqiang Hu Zhihua Xing David N Criddle Qing Xia Wei Huang Robert Sutton

J Ethnopharmacol 2018 Oct 2;224:261-272. Epub 2018 Jun 2.

Liverpool Pancreatitis Study Group, Institute of Translational Medicine, University of Liverpool, Liverpool L69 3GE, UK.

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October 2018

Earlier surgery improves outcomes from painful chronic pancreatitis.

Authors:
Nengwen Ke Dan Jia Wei Huang Quentin M Nunes John A Windsor Xubao Liu Robert Sutton

Medicine (Baltimore) 2018 May;97(19):e0651

Department of Pancreatic Surgery Division of General Practice Department of Integrated Traditional Chinese and Western Medicine (WH), West China Hospital, Sichuan University, Chengdu, China NIHR Liverpool Pancreas Biomedical Research Unit, Royal Liverpool University Hospital, University of Liverpool, Liverpool, UK Department of Surgery (JAW), University of Auckland, Auckland, New Zealand.

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May 2018

Intracellular rupture, exocytosis and actin interaction of endocytic vacuoles in pancreatic acinar cells: initiating events in acute pancreatitis.

Authors:
Michael Chvanov Francesca De Faveri Danielle Moore Mark W Sherwood Muhammad Awais Svetlana Voronina Robert Sutton David N Criddle Lee Haynes Alexei V Tepikin

J Physiol 2018 07 6;596(13):2547-2564. Epub 2018 Jun 6.

Department of Cellular and Molecular Physiology and NIHR Liverpool Pancreas Biomedical Research Unit, University of Liverpool, Liverpool, UK.

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July 2018

Physiology-directed cardiopulmonary resuscitation: advances in precision monitoring during cardiac arrest.

Authors:
Alexandra M Marquez Ryan W Morgan Catherine E Ross Robert A Berg Robert M Sutton

Curr Opin Crit Care 2018 06;24(3):143-150

Division of Critical Care Medicine, Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

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June 2018

Oxidative stress alters mitochondrial bioenergetics and modifies pancreatic cell death independently of cyclophilin D, resulting in an apoptosis-to-necrosis shift.

Authors:
Jane A Armstrong Nicole J Cash Yulin Ouyang Jack C Morton Michael Chvanov Diane Latawiec Muhammad Awais Alexei V Tepikin Robert Sutton David N Criddle

J Biol Chem 2018 05 6;293(21):8032-8047. Epub 2018 Apr 6.

From the Departments of Cellular & Molecular Physiology and

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May 2018

Improving outcomes after pediatric cardiac arrest - the ICU-Resuscitation Project: study protocol for a randomized controlled trial.

Authors:
Ron W Reeder Alan Girling Heather Wolfe Richard Holubkov Robert A Berg Maryam Y Naim Kathleen L Meert Bradley Tilford Joseph A Carcillo Melinda Hamilton Matthew Bochkoris Mark Hall Tensing Maa Andrew R Yates Anil Sapru Robert Kelly Myke Federman J Michael Dean Patrick S McQuillen Deborah Franzon Murray M Pollack Ashley Siems John Diddle David L Wessel Peter M Mourani Carleen Zebuhr Robert Bishop Stuart Friess Candice Burns Shirley Viteri David A Hehir R Whitney Coleman Tammara L Jenkins Daniel A Notterman Robert F Tamburro Robert M Sutton

Trials 2018 Apr 3;19(1):213. Epub 2018 Apr 3.

Department of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA, USA.

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April 2018

Characterization of Pediatric In-Hospital Cardiopulmonary Resuscitation Quality Metrics Across an International Resuscitation Collaborative.

Authors:
Dana E Niles Jordan Duval-Arnould Sophie Skellett Lynda Knight Felice Su Tia T Raymond Todd Sweberg Anita I Sen Dianne L Atkins Stuart H Friess Allan R de Caen Hiroshi Kurosawa Robert M Sutton Heather Wolfe Robert A Berg Annemarie Silver Elizabeth A Hunt Vinay M Nadkarni

Pediatr Crit Care Med 2018 05;19(5):421-432

The Center for Simulation, Advanced Education, and Innovation, The Children's Hospital of Philadelphia, Philadelphia, PA.

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May 2018

Focused Training for the Handover of Critical Patient Information During Simulated Pediatric Emergencies.

Authors:
Andrew J Lautz Kelly C Martin Akira Nishisaki Christopher P Bonafide Roberta L Hales Elizabeth A Hunt Vinay M Nadkarni Robert M Sutton Donald L Boyer

Hosp Pediatr 2018 04 7;8(4):227-231. Epub 2018 Mar 7.

Divisions of Critical Care Medicine and.

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April 2018

PET-PANC: multicentre prospective diagnostic accuracy and health economic analysis study of the impact of combined modality 18fluorine-2-fluoro-2-deoxy-d-glucose positron emission tomography with computed tomography scanning in the diagnosis and management of pancreatic cancer.

Authors:
Paula Ghaneh Robert Hanson Andrew Titman Gill Lancaster Catrin Plumpton Huw Lloyd-Williams Seow Tien Yeo Rhiannon Tudor Edwards Colin Johnson Mohammed Abu Hilal Antony P Higginson Tom Armstrong Andrew Smith Andrew Scarsbrook Colin McKay Ross Carter Robert P Sutcliffe Simon Bramhall Hemant M Kocher David Cunningham Stephen P Pereira Brian Davidson David Chang Saboor Khan Ian Zealley Debashis Sarker Bilal Al Sarireh Richard Charnley Dileep Lobo Marianne Nicolson Christopher Halloran Michael Raraty Robert Sutton Sobhan Vinjamuri Jonathan Evans Fiona Campbell Jon Deeks Bal Sanghera Wai-Lup Wong John P Neoptolemos

Health Technol Assess 2018 02;22(7):1-114

Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, UK.

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February 2018

EPC/HPSG evidence-based guidelines for the management of pediatric pancreatitis.

Authors:
Andrea Párniczky Maisam Abu-El-Haija Sohail Husain Mark Lowe Grzegorz Oracz Miklós Sahin-Tóth Flóra K Szabó Aliye Uc Michael Wilschanski Heiko Witt László Czakó Tassos Grammatikopoulos Ib Christian Rasmussen Robert Sutton Péter Hegyi

Pancreatology 2018 Mar 4;18(2):146-160. Epub 2018 Jan 4.

Institute for Translational Medicine, University of Pécs, Pécs, Hungary; First Department of Medicine, University of Szeged, Szeged, Hungary. Electronic address:

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March 2018

Cerebral mitochondrial dysfunction associated with deep hypothermic circulatory arrest in neonatal swine.

Authors:
Constantine D Mavroudis Michael Karlsson Tiffany Ko Marco Hefti Javier I Gentile Ryan W Morgan Ross Plyler Kobina G Mensah-Brown Timothy W Boorady Richard W Melchior Tami M Rosenthal Brandon C Shade Kellie L Schiavo Susan C Nicolson Thomas L Spray Robert M Sutton Robert A Berg Daniel J Licht J William Gaynor Todd J Kilbaugh

Eur J Cardiothorac Surg 2018 07;54(1):162-168

Department of Anesthesia and Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.

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July 2018

Association Between Diastolic Blood Pressure During Pediatric In-Hospital Cardiopulmonary Resuscitation and Survival.

Authors:
Robert A Berg Robert M Sutton Ron W Reeder John T Berger Christopher J Newth Joseph A Carcillo Patrick S McQuillen Kathleen L Meert Andrew R Yates Rick E Harrison Frank W Moler Murray M Pollack Todd C Carpenter David L Wessel Tammara L Jenkins Daniel A Notterman Richard Holubkov Robert F Tamburro J Michael Dean Vinay M Nadkarni

Circulation 2018 04 26;137(17):1784-1795. Epub 2017 Dec 26.

Department of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, University of Pennsylvania (R.A.B., R.M.S., V.M.N).

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April 2018

Pediatric In-Hospital Cardiac Arrest Secondary to Acute Pulmonary Embolism.

Authors:
Ryan W Morgan Hannah R Stinson Heather Wolfe Robert B Lindell Alexis A Topjian Vinay M Nadkarni Robert M Sutton Robert A Berg Todd J Kilbaugh

Crit Care Med 2018 03;46(3):e229-e234

Division of Critical Care Medicine, Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, PA.

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March 2018

Pulmonary Vasodilator Therapy in Shock-associated Cardiac Arrest.

Authors:
Ryan W Morgan Robert M Sutton Michael Karlsson Andrew J Lautz Constantine D Mavroudis William P Landis Yuxi Lin Sejin Jeong Nancy Craig Vinay M Nadkarni Todd J Kilbaugh Robert A Berg

Am J Respir Crit Care Med 2018 04;197(7):905-912

1 Department of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; and.

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April 2018

TRO40303 Ameliorates Alcohol-Induced Pancreatitis Through Reduction of Fatty Acid Ethyl Ester-Induced Mitochondrial Injury and Necrotic Cell Death.

Authors:
Muhammad Ahsan Javed Li Wen Muhammad Awais Diane Latawiec Wei Huang Michael Chvanov Sophie Schaller Thierry Bordet Magali Michaud Rebecca Pruss Alexei Tepikin David Criddle Robert Sutton

Pancreas 2018 01;47(1):18-24

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January 2018

Functional and non-functional pancreatic neuroendocrine tumours: ENETS or AJCC TNM staging system?

Authors:
Min Yang Neng-Wen Ke Yi Zhang Chun-Lu Tan Bo-Le Tian Xu-Bao Liu Wei Huang Quentin Nunes Robert Sutton

Oncotarget 2017 Oct 7;8(47):82784-82795. Epub 2017 Aug 7.

National Institute for Health Research (NIHR) Liverpool Pancreas Biomedical Research Unit, Royal Liverpool University Hospital, University of Liverpool, Liverpool, UK.

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October 2017

Failure of Invasive Airway Placement on the First Attempt Is Associated With Progression to Cardiac Arrest in Pediatric Acute Respiratory Compromise.

Authors:
Hannah R Stinson Vijay Srinivasan Alexis A Topjian Robert M Sutton Vinay M Nadkarni Robert A Berg Tia T Raymond

Pediatr Crit Care Med 2018 01;19(1):9-16

Department of Pediatrics and Critical Care Medicine, Section of Pediatric Cardiac Intensive Care, Medical City Children's Hospital, Dallas, TX.

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January 2018

Systemic histone release disrupts plasmalemma and contributes to necrosis in acute pancreatitis.

Authors:
Peter Szatmary Tingting Liu Simon T Abrams Svetlana Voronina Li Wen Michael Chvanov Wei Huang Guozheng Wang David N Criddle Alexey V Tepikin Cheng-Hock Toh Robert Sutton

Pancreatology 2017 Nov - Dec;17(6):884-892. Epub 2017 Oct 7.

NIHR Liverpool Pancreas Biomedical Research Unit, Royal Liverpool University Hospital, University of Liverpool, Liverpool, L69 3GA, UK.

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July 2018

The Future of Resuscitation: Personalized Physiology-Guided Cardiopulmonary Resuscitation.

Authors:
Ryan W Morgan Robert M Sutton Robert A Berg

Pediatr Crit Care Med 2017 11;18(11):1084-1086

Division of Critical Care Medicine, Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, PA.

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November 2017

Cardiopulmonary Resuscitation in Pediatric and Cardiac Intensive Care Units.

Authors:
Robert M Sutton Ryan W Morgan Todd J Kilbaugh Vinay M Nadkarni Robert A Berg

Pediatr Clin North Am 2017 10 18;64(5):961-972. Epub 2017 Aug 18.

Department of Anesthesia and Critical Care Medicine, University of Pennsylvania School of Medicine, Children's Hospital of Philadelphia, 3401 Civic Center Boulevard, Philadelphia, PA 19104, USA.

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October 2017

Dynamic monitoring of p53 translocation to mitochondria for the analysis of specific inhibitors using luciferase-fragment complementation.

Authors:
Natsumi Noda Raheela Awais Robert Sutton Muhammad Awais Takeaki Ozawa

Biotechnol Bioeng 2017 12 6;114(12):2818-2827. Epub 2017 Oct 6.

Department of Chemistry, School of Science, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.

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December 2017

Response to letter to the editor: Sepsis-associated in-hospital cardiac arrest.

Authors:
Ryan W Morgan Julie C Fitzgerald Scott L Weiss Vinay M Nadkarni Robert M Sutton Robert A Berg

J Crit Care 2017 08 21;40:291. Epub 2017 Jun 21.

The Children's Hospital of Philadelphia, Department of Anesthesiology and Critical Care Medicine, 34(th) Street & Civic Center Boulevard, Suite 8566, Philadelphia, PA 19104, USA. Electronic address:

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August 2017

Selective inhibition of BET proteins reduces pancreatic damage and systemic inflammation in bile acid- and fatty acid ethyl ester- but not caerulein-induced acute pancreatitis.

Authors:
Wei Huang Andrea C Haynes Rajarshi Mukherjee Li Wen Diane Latawiec Alexei V Tepikin David N Criddle Rab K Prinjha Nicholas Smithers Robert Sutton

Pancreatology 2017 Sep - Oct;17(5):689-697. Epub 2017 Jun 10.

Department of Molecular and Clinical Cancer Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, UK; NIHR Liverpool Pancreas Biomedical Research Unit, Royal Liverpool University Hospital, Institute of Translational Medicine, University of Liverpool, Liverpool, UK. Electronic address:

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June 2018

Chai-Qin-Cheng-Qi Decoction and Carbachol Improve Intestinal Motility by Regulating Protein Kinase C-Mediated Ca Release in Colonic Smooth Muscle Cells in Rats with Acute Necrotising Pancreatitis.

Authors:
Chen-Long Zhang Zi-Qi Lin Rui-Jie Luo Xiao-Xin Zhang Jia Guo Wei Wu Na Shi Li-Hui Deng Wei-Wei Chen Xiao-Ying Zhang Shameena Bharucha Wei Huang Robert Sutton John A Windsor Ping Xue Qing Xia

Evid Based Complement Alternat Med 2017 26;2017:5864945. Epub 2017 Apr 26.

Department of Integrated Traditional Chinese and Western Medicine, Sichuan Provincial Pancreatitis Centre, West China Hospital, Sichuan University, Chengdu, China.

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April 2017

Synthesis of thioether andrographolide derivatives and their inhibitory effect against cancer cells.

Authors:
Yi Liu Ren-Ming Liang Qing-Ping Ma Kai Xu Xin-Yong Liang Wei Huang Robert Sutton Jie Ding Paul M O'Neil Chun-Ru Cheng

Medchemcomm 2017 Jun 28;8(6):1268-1274. Epub 2017 Apr 28.

School of Chemical Engineering , Institute of Pharmaceutical Engineering Technology and Application , Key Laboratory of Green Chemistry of Sichuan Institutes of Higher Education , Sichuan University of Science & Engineering , Xueyuan Street 180, Huixing Road , Zigong , Sichuan 643000 , People's Republic of China . Email: ; Email: ; Tel: +86 813 5505601.

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June 2017

Sepsis-associated in-hospital cardiac arrest: Epidemiology, pathophysiology, and potential therapies.

Authors:
Ryan W Morgan Julie C Fitzgerald Scott L Weiss Vinay M Nadkarni Robert M Sutton Robert A Berg

J Crit Care 2017 08 31;40:128-135. Epub 2017 Mar 31.

The Children's Hospital of Philadelphia, Department of Anesthesiology and Critical Care Medicine, 34th Street & Civic Center Boulevard, Suite 8566, Philadelphia 19104, PA, USA. Electronic address:

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August 2017

Improved Retention of Chest Compression Psychomotor Skills With Brief "Rolling Refresher" Training.

Authors:
Dana E Niles Akira Nishisaki Robert M Sutton Okan U Elci Peter A Meaney Kathleen A OʼConnor Jessica Leffelman Jo Kramer-Johansen Robert A Berg Vinay Nadkarni

Simul Healthc 2017 Aug;12(4):213-219

From the Center for Simulation, Advanced Education and Innovation (D.E.N., A.N., J.L., V.N.), Department of Anesthesiology and Critical Care Medicine (A.N., R.M.S., P.A.M., R.A.B., V.N.), Westat-Biostatistics and Data Management Core (O.U.E.), Department of Nursing, The Children's Hospital of Philadelphia (K.A.O), PA; and Norwegian National Advisory Unit for Prehospital Emergency Care (NAKOS) and Department of Anaesthesiology (J.K.-J.), Oslo University Hospital and University of Oslo, Oslo, Norway.

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August 2017

Vancomycin-resistant enterococci in acute myeloid leukemia and myelodysplastic syndrome patients undergoing induction chemotherapy with idarubicin and cytarabine.

Authors:
Ronald W Heisel Robert R Sutton Gerard P Mascara Daniel G Winger David R Weber Seah H Lim Louise-Marie Oleksiuk

Leuk Lymphoma 2017 11 28;58(11):2565-2572. Epub 2017 Mar 28.

a Department of Pharmacy , University of Pittsburgh Medical Center , Pittsburgh , PA , USA.

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November 2017

Efficacy of pancreatic enzyme replacement therapy in chronic pancreatitis: systematic review and meta-analysis.

Authors:
Daniel de la Iglesia-García Wei Huang Peter Szatmary Iria Baston-Rey Jaime Gonzalez-Lopez Guillermo Prada-Ramallal Rajarshi Mukherjee Quentin M Nunes J Enrique Domínguez-Muñoz Robert Sutton

Gut 2017 08 9;66(8):1354-1355. Epub 2016 Dec 9.

NIHR Liverpool Pancreas Biomedical Research Unit, Royal Liverpool University Hospital, University of Liverpool, Liverpool, UK.

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August 2017

A hemodynamic-directed approach to pediatric cardiopulmonary resuscitation (HD-CPR) improves survival.

Authors:
Ryan W Morgan Todd J Kilbaugh Wesley Shoap George Bratinov Yuxi Lin Ting-Chang Hsieh Vinay M Nadkarni Robert A Berg Robert M Sutton

Resuscitation 2017 02 5;111:41-47. Epub 2016 Dec 5.

The Children's Hospital of Philadelphia, Department of Anesthesiology and Critical Care Medicine, 34th Street & Civic Center Boulevard, Philadelphia, PA 19104, United States.

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February 2017

Defining drug response for stratified medicine.

Authors:
Mike Lonergan Stephen J Senn Christine McNamee Ann K Daly Robert Sutton Andrew Hattersley Ewan Pearson Munir Pirmohamed

Drug Discov Today 2017 01 3;22(1):173-179. Epub 2016 Nov 3.

Wolfson Centre for Personalised Medicine, University of Liverpool, Liverpool L69 3GL, UK. Electronic address:

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January 2017

Length of Variable Numbers of Tandem Repeats in the Carboxyl Ester Lipase (CEL) Gene May Confer Susceptibility to Alcoholic Liver Cirrhosis but Not Alcoholic Chronic Pancreatitis.

Authors:
Karianne Fjeld Sebastian Beer Marianne Johnstone Constantin Zimmer Joachim Mössner Claudia Ruffert Mario Krehan Christian Zapf Pål Rasmus Njølstad Stefan Johansson Peter Bugert Fabio Miyajima Triantafillos Liloglou Laura J Brown Simon A Winn Kelly Davies Diane Latawiec Bridget K Gunson David N Criddle Munir Pirmohamed Robert Grützmann Patrick Michl William Greenhalf Anders Molven Robert Sutton Jonas Rosendahl

PLoS One 2016 1;11(11):e0165567. Epub 2016 Nov 1.

Department of Internal Medicine I, Martin Luther University, Halle, Germany.

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June 2017

Blood Pressure- and Coronary Perfusion Pressure-Targeted Cardiopulmonary Resuscitation Improves 24-Hour Survival From Ventricular Fibrillation Cardiac Arrest.

Authors:
Maryam Y Naim Robert M Sutton Stuart H Friess George Bratinov Utpal Bhalala Todd J Kilbaugh Joshua W Lampe Vinay M Nadkarni Lance B Becker Robert A Berg

Crit Care Med 2016 Nov;44(11):e1111-e1117

1Department of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA. 2Department of Pediatrics, St. Louis Children's Hospital, Washington University in St. Louis School of Medicine, St. Louis, MO. 3Department of Anesthesiology and Critical Care Medicine, Bloomberg Children's Center, Johns Hopkins Hospital, Johns Hopkins University School of Medicine, Baltimore, MD. 4Department of Emergency Medicine, The Hospital of the University of Pennsylvania, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

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November 2016

The authors reply.

Authors:
Robert A Berg Vinay M Nadkarni Robert M Sutton Michael Dean Murray Pollack

Crit Care Med 2016 08;44(8):e762-4

Department of Anesthesia and Critical Care/Division of Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, PA; Department of Pediatrics/Division of Critical Care Medicine, University of Utah, Salt Lake City, UT; Department of Pediatrics/Division of Critical Care Medicine, Children's National Medical Center, Washington, DC.

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August 2016