Robert St Onge

Robert St Onge

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Robert St Onge

Robert St Onge

Publications by authors named "Robert St Onge"

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Community members in activated sludge as determined by molecular probe technology.

Water Res 2020 Jan 10;168:115104. Epub 2019 Oct 10.

Stanford Genome Technology Center, Palo Alto, CA, 94304, USA; Department of Biochemistry, Stanford University Medical College, Stanford, CA, 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.watres.2019.115104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873225PMC
January 2020

Improved discovery of genetic interactions using CRISPRiSeq across multiple environments.

Genome Res 2019 04 19;29(4):668-681. Epub 2019 Feb 19.

Department of Genetics, Stanford University School of Medicine, Stanford, California 94305, USA.

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http://dx.doi.org/10.1101/gr.246603.118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442382PMC
April 2019

A biosensor-based approach reveals links between efflux pump expression and cell cycle regulation in pleiotropic drug resistance of yeast.

J Biol Chem 2019 01 4;294(4):1257-1266. Epub 2018 Dec 4.

From the Department of Biochemistry, Stanford Genome Technology Center, Stanford University School of Medicine, Palo Alto, California 94304

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http://dx.doi.org/10.1074/jbc.RA118.003904DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349095PMC
January 2019

A scalable double-barcode sequencing platform for characterization of dynamic protein-protein interactions.

Nat Commun 2017 05 25;8:15586. Epub 2017 May 25.

Laufer Center for Physical and Quantitative Biology, Stony Brook University, Stony Brook, New York 11794-5252, USA.

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http://dx.doi.org/10.1038/ncomms15586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458509PMC
May 2017

Identification of Chemical-Genetic Interactions via Parallel Analysis of Barcoded Yeast Strains.

Cold Spring Harb Protoc 2016 09 1;2016(9). Epub 2016 Sep 1.

Stanford Genome Technology Center, Department of Biochemistry, Stanford University, Palo Alto, California 94304;

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http://dx.doi.org/10.1101/pdb.prot088054DOI Listing
September 2016

Systematic Mapping of Chemical-Genetic Interactions in Saccharomyces cerevisiae.

Cold Spring Harb Protoc 2016 09 1;2016(9). Epub 2016 Sep 1.

Stanford Genome Technology Center, Department of Biochemistry, Stanford University, Palo Alto, California 94304;

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http://dx.doi.org/10.1101/pdb.top077701DOI Listing
September 2016

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.

Authors:
Wesley C Van Voorhis John H Adams Roberto Adelfio Vida Ahyong Myles H Akabas Pietro Alano Aintzane Alday Yesmalie Alemán Resto Aishah Alsibaee Ainhoa Alzualde Katherine T Andrews Simon V Avery Vicky M Avery Lawrence Ayong Mark Baker Stephen Baker Choukri Ben Mamoun Sangeeta Bhatia Quentin Bickle Lotfi Bounaadja Tana Bowling Jürgen Bosch Lauren E Boucher Fabrice F Boyom Jose Brea Marian Brennan Audrey Burton Conor R Caffrey Grazia Camarda Manuela Carrasquilla Dee Carter Maria Belen Cassera Ken Chih-Chien Cheng Worathad Chindaudomsate Anthony Chubb Beatrice L Colon Daisy D Colón-López Yolanda Corbett Gregory J Crowther Noemi Cowan Sarah D'Alessandro Na Le Dang Michael Delves Joseph L DeRisi Alan Y Du Sandra Duffy Shimaa Abd El-Salam El-Sayed Michael T Ferdig José A Fernández Robledo David A Fidock Isabelle Florent Patrick V T Fokou Ani Galstian Francisco Javier Gamo Suzanne Gokool Ben Gold Todd Golub Gregory M Goldgof Rajarshi Guha W Armand Guiguemde Nil Gural R Kiplin Guy Michael A E Hansen Kirsten K Hanson Andrew Hemphill Rob Hooft van Huijsduijnen Takaaki Horii Paul Horrocks Tyler B Hughes Christopher Huston Ikuo Igarashi Katrin Ingram-Sieber Maurice A Itoe Ajit Jadhav Amornrat Naranuntarat Jensen Laran T Jensen Rays H Y Jiang Annette Kaiser Jennifer Keiser Thomas Ketas Sebastien Kicka Sunyoung Kim Kiaran Kirk Vidya P Kumar Dennis E Kyle Maria Jose Lafuente Scott Landfear Nathan Lee Sukjun Lee Adele M Lehane Fengwu Li David Little Liqiong Liu Manuel Llinás Maria I Loza Aristea Lubar Leonardo Lucantoni Isabelle Lucet Louis Maes Dalu Mancama Nuha R Mansour Sandra March Sheena McGowan Iset Medina Vera Stephan Meister Luke Mercer Jordi Mestres Alvine N Mfopa Raj N Misra Seunghyun Moon John P Moore Francielly Morais Rodrigues da Costa Joachim Müller Arantza Muriana Stephen Nakazawa Hewitt Bakela Nare Carl Nathan Nathalie Narraidoo Sujeevi Nawaratna Kayode K Ojo Diana Ortiz Gordana Panic George Papadatos Silvia Parapini Kailash Patra Ngoc Pham Sarah Prats David M Plouffe Sally-Ann Poulsen Anupam Pradhan Celia Quevedo Ronald J Quinn Christopher A Rice Mohamed Abdo Rizk Andrea Ruecker Robert St Onge Rafaela Salgado Ferreira Jasmeet Samra Natalie G Robinett Ulrich Schlecht Marjorie Schmitt Filipe Silva Villela Francesco Silvestrini Robert Sinden Dennis A Smith Thierry Soldati Andreas Spitzmüller Serge Maximilian Stamm David J Sullivan William Sullivan Sundari Suresh Brian M Suzuki Yo Suzuki S Joshua Swamidass Donatella Taramelli Lauve R Y Tchokouaha Anjo Theron David Thomas Kathryn F Tonissen Simon Townson Abhai K Tripathi Valentin Trofimov Kenneth O Udenze Imran Ullah Cindy Vallieres Edgar Vigil Joseph M Vinetz Phat Voong Vinh Hoan Vu Nao-Aki Watanabe Kate Weatherby Pamela M White Andrew F Wilks Elizabeth A Winzeler Edward Wojcik Melanie Wree Wesley Wu Naoaki Yokoyama Paul H A Zollo Nada Abla Benjamin Blasco Jeremy Burrows Benoît Laleu Didier Leroy Thomas Spangenberg Timothy Wells Paul A Willis

PLoS Pathog 2016 07 28;12(7):e1005763. Epub 2016 Jul 28.

Medicines for Malaria Venture, Geneva, Switzerland.

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http://dx.doi.org/10.1371/journal.ppat.1005763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965013PMC
July 2016

Distinct patterns of Cas9 mismatch tolerance in vitro and in vivo.

Nucleic Acids Res 2016 06 19;44(11):5365-77. Epub 2016 May 19.

Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA Stanford Genome Technology Center, Palo Alto, CA 94304, USA

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http://dx.doi.org/10.1093/nar/gkw417DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914125PMC
June 2016

Quantitative CRISPR interference screens in yeast identify chemical-genetic interactions and new rules for guide RNA design.

Genome Biol 2016 Mar 8;17:45. Epub 2016 Mar 8.

Stanford Genome Technology Center, Department of Biochemistry, Stanford University, 3165 Porter Drive, Palo Alto, CA, 94304, USA.

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http://dx.doi.org/10.1186/s13059-016-0900-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784398PMC
March 2016

Mitochondrial protein sorting as a therapeutic target for ATP synthase disorders.

Nat Commun 2014 Dec 18;5:5585. Epub 2014 Dec 18.

1] European Molecular Biology Laboratory (EMBL), Genome Biology Unit, 69117 Heidelberg, Germany [2] Stanford Genome Technology Center, Stanford University, Palo Alto, California 94304, USA [3] Department of Genetics, Stanford University School of Medicine, Stanford, California, USA.

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http://dx.doi.org/10.1038/ncomms6585DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284804PMC
December 2014

A functional screen for copper homeostasis genes identifies a pharmacologically tractable cellular system.

BMC Genomics 2014 Apr 5;15:263. Epub 2014 Apr 5.

Stanford Genome Technology Center, Department of Biochemistry, Stanford University, 855 S California Avenue, Palo Alto, CA 94304, USA.

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http://dx.doi.org/10.1186/1471-2164-15-263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023593PMC
April 2014

PITPs as targets for selectively interfering with phosphoinositide signaling in cells.

Nat Chem Biol 2014 Jan 24;10(1):76-84. Epub 2013 Nov 24.

1] Department of Molecular and Cellular Medicine, Texas A&M University College Station, Texas, USA. [2] Department of Biochemistry and Biophysics, Texas A&M University College Station, Texas, USA. [3] Department of Chemistry, Texas A&M University College Station, Texas, USA. [4] Department of Cell and Developmental Biology, Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA.

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http://dx.doi.org/10.1038/nchembio.1389DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059020PMC
January 2014

Cationic amphiphilic drugs are potent inhibitors of yeast sporulation.

PLoS One 2012 8;7(8):e42853. Epub 2012 Aug 8.

Stanford Genome Technology Center, Stanford University, Palo Alto, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0042853PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414501PMC
February 2013

Identification of drug targets by chemogenomic and metabolomic profiling in yeast.

Pharmacogenet Genomics 2012 Dec;22(12):877-86

Department of Anesthesia, Stanford University School of Medicine, Stanford University, Stanford, California 94305, USA.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/FPC.0b013e32835aa888DOI Listing
December 2012

Forward chemical genetics in yeast for discovery of chemical probes targeting metabolism.

Molecules 2012 Nov 5;17(11):13098-115. Epub 2012 Nov 5.

Department of Biochemistry, Stanford Genome Technology Center, Stanford University, Stanford, CA 94305, USA.

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http://dx.doi.org/10.3390/molecules171113098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539408PMC
November 2012

Multiplex assay for condition-dependent changes in protein-protein interactions.

Proc Natl Acad Sci U S A 2012 Jun 21;109(23):9213-8. Epub 2012 May 21.

Stanford Genome Technology Center, Department of Biochemistry, Stanford University, Palo Alto, CA 94304, USA.

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http://dx.doi.org/10.1073/pnas.1204952109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384208PMC
June 2012

A yeast-based assay identifies drugs active against human mitochondrial disorders.

Proc Natl Acad Sci U S A 2011 Jul 29;108(29):11989-94. Epub 2011 Jun 29.

INSERM U613; Université de Brest, Faculté de Médecine et des Sciences de la Santé; Etablissement Français du Sang (EFS) Bretagne; Centre Hospitalier Régional Universitaire Brest, Hop Morvan, Laboratoire de Génétique Moléculaire, F-29200 Brest, France.

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http://dx.doi.org/10.1073/pnas.1101478108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141935PMC
July 2011

The synthetic genetic interaction network reveals small molecules that target specific pathways in Sacchromyces cerevisiae.

Mol Biosyst 2011 Jun 12;7(6):2019-30. Epub 2011 Apr 12.

Department of Chemistry and Biochemistry, University of California Santa Cruz, 1156 High St., Santa Cruz, CA 95064, USA.

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http://dx.doi.org/10.1039/c0mb00298dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653045PMC
June 2011

Exploring gene function and drug action using chemogenomic dosage assays.

Methods Enzymol 2010 1;470:233-55. Epub 2010 Mar 1.

Department of Pharmaceutical Sciences, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/S0076-6879(10)70010-0DOI Listing
January 2011

Gene annotation and drug target discovery in Candida albicans with a tagged transposon mutant collection.

PLoS Pathog 2010 Oct 7;6(10):e1001140. Epub 2010 Oct 7.

Department of Genetics, Stanford University, Palo Alto, California, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1001140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951378PMC
October 2010

Highly-multiplexed barcode sequencing: an efficient method for parallel analysis of pooled samples.

Nucleic Acids Res 2010 Jul 11;38(13):e142. Epub 2010 May 11.

Department of Molecular Genetics, University of Toronto, 1 King's College Circle, Toronto, Ontario M5S 1A8, Canada.

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http://dx.doi.org/10.1093/nar/gkq368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910071PMC
July 2010

Multiplex identification of microbes.

Appl Environ Microbiol 2010 Jun 23;76(12):3904-10. Epub 2010 Apr 23.

Department of Biochemistry, Stanford Genome Technology Center, Stanford University Medical School, 855 California Avenue, Palo Alto, California 94304, USA.

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http://dx.doi.org/10.1128/AEM.02785-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2893500PMC
June 2010

Yeast chemical genomics and drug discovery: an update.

Trends Pharmacol Sci 2008 Oct 26;29(10):499-504. Epub 2008 Aug 26.

Department of Genetics, Stanford University, Palo Alto, CA 94305, USA.

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http://dx.doi.org/10.1016/j.tips.2008.07.006DOI Listing
October 2008

An integrated platform of genomic assays reveals small-molecule bioactivities.

Nat Chem Biol 2008 Aug 11;4(8):498-506. Epub 2008 Jul 11.

Department of Genetics, Stanford University, Mail Stop-5120, Palo Alto, California 94305, USA.

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http://dx.doi.org/10.1038/nchembio.100DOI Listing
August 2008

Defining genetic interaction.

Proc Natl Acad Sci U S A 2008 Mar 27;105(9):3461-6. Epub 2008 Feb 27.

Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, 250 Longwood Avenue, Boston, MA 02115, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0712255105
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http://dx.doi.org/10.1073/pnas.0712255105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265146PMC
March 2008

Genome-wide requirements for resistance to functionally distinct DNA-damaging agents.

PLoS Genet 2005 Aug 19;1(2):e24. Epub 2005 Aug 19.

Department of Genetics, Stanford University School of Medicine, Stanford, California, USA.

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http://dx.doi.org/10.1371/journal.pgen.0010024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1189734PMC
August 2005

A role for the phosphorylation of hRad9 in checkpoint signaling.

J Biol Chem 2003 Jul 6;278(29):26620-8. Epub 2003 May 6.

Division of Cancer Biology and Genetics, Queen's University Cancer Research Institute, Kingston, Ontario, Canada.

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http://dx.doi.org/10.1074/jbc.M303134200DOI Listing
July 2003