Robert Spiera

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Robert Spiera

Publications by authors named "Robert Spiera"

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95Publications

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Plasmacytoid dendritic cells promote systemic sclerosis with a key role for TLR8.

Sci Transl Med 2018 Jan;10(423)

Autoimmunity and Inflammation Program, HSS Research Institute, Hospital for Special Surgery, New York, NY 10021, USA.

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January 2018

Integration of capillary microscopy and dermoscopy into the rheumatology fellow curriculum.

Clin Exp Rheumatol 2017 Sep-Oct;35(5):850-852. Epub 2017 Feb 10.

Department of Rheumatology, Hospital for Special Surgery, New York, USA.

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November 2017

Trial of Tocilizumab in Giant-Cell Arteritis.

N Engl J Med 2017 07;377(4):317-328

From the Massachusetts General Hospital Rheumatology Unit, Harvard Medical School, Boston (J.H.S., S.H.U.); Roche Products, Welwyn Garden City (K.T., S.D., N.C.), and Southend University Hospital NHS Foundation Trust, Westcliff-on-Sea (B.D.) - both in the United Kingdom; Genentech, South San Francisco, CA (M.K.); the Department of Rheumatology, Medicine III, University Medical Center and Faculty of Medicine Technische Universität Dresden, Dresden (M.A.), Friedrich-Alexander-University Erlangen-Nürnberg, Department of Internal Medicine 3-Rheumatology and Immunology (J.R.), and Institute of Clinical Immunology (G.S.), Universitätsklinikum Erlangen, Erlangen, and the Division of Rheumatology and Clinical Immunology, Department of Medicine IV, University of Munich, Munich (H.S.-K.) - all in Germany; the Department of General Internal Medicine, University Hospitals Gasthuisberg, Leuven, Belgium (D.B.); the Department of Rheumatology and Clinical Immunology, University of Groningen, University Medical Center, Groningen, the Netherlands (E.B.); the Department of Autoimmune Diseases, Hospital Clínic, University of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona (M.C.C.); the Division of Internal Medicine, Azienda Ospedaliera-Istituto di Ricovero e Cura a Carattere Scientifico di Reggio Emilia and Università di Modena e Reggio Emilia, Reggio Emilia, Italy (C.S.); and Hospital for Special Surgery, New York (R.S.).

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July 2017

Proteomic Analysis of Sera from Individuals with Diffuse Cutaneous Systemic Sclerosis Reveals a Multianalyte Signature Associated with Clinical Improvement during Imatinib Mesylate Treatment.

J Rheumatol 2017 May 15;44(5):631-638. Epub 2017 Mar 15.

From the Division of Immunology and Rheumatology, Stanford University School of Medicine; Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford; Department of Rheumatology, Palo Alto VA Health Care System, Palo Alto, California; Department of Rheumatology, Hospital for Special Surgery, New York, New York, USA.

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May 2017

Comparison of change in end tidal carbon dioxide after three minutes of step exercise between systemic sclerosis patients with and without pulmonary hypertension.

Rheumatology (Oxford) 2017 01 25;56(1):87-94. Epub 2016 Oct 25.

Division of Rheumatology, Department of Medicine, Hospital for Special Surgery.

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January 2017

The Recurrence of Digital Ulcers in Patients with Systemic Sclerosis after Discontinuation of Oral Treprostinil.

J Rheumatol 2016 09 15;43(9):1665-71. Epub 2016 Jun 15.

From the Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, Maryland; University of Michigan, Ann Arbor, Michigan; Cleveland Clinic, Cleveland, Ohio; Medical College of Wisconsin, Milwaukee, Wisconsin; University of Utah, Salt Lake City, Utah; New York University (NYU) Langone Medical Center, Lake Success; Hospital for Special Surgery, New York, New York; Benaroya Research Institute at Virginia Mason, Seattle, Washington; Georgetown University, Washington, DC; University of North Carolina at Chapel Hill, Chapel Hill; United Therapeutics Corporation, Research Triangle Park, North Carolina, USA.A.A. Shah, MD, MHS, Assistant Professor of Medicine, Director of Clinical and Translational Research, Johns Hopkins Scleroderma Center, Division of Rheumatology, Johns Hopkins University School of Medicine; E. Schiopu, MD, Assistant Professor of Internal Medicine, University of Michigan; S. Chatterjee, MD, Associate Professor of Medicine, Cleveland Clinic; M.E. Csuka, MD, Professor of Medicine, Medical College of Wisconsin; T. Frech, MD, Associate Professor of Medicine, University of Utah; A. Goldberg, MD, Clinical Assistant Professor, NYU Langone Medical Center; R. Spiera, MD, Professor of Clinical Medicine, Hospital for Special Surgery; S.L. Peng, MD, PhD, Vice President, Clinical Development, Benaroya Research Institute at Virginia Mason; R.J. McBride, DrPH, Student, University of North Carolina at Chapel Hill; J.M. Cleveland, MS, Director, Biostatistics, United Therapeutics Corp.; V. Steen, MD, Professor of Medicine, Georgetown University.

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September 2016

B-cell-targeted therapy in systemic vasculitis.

Curr Opin Rheumatol 2016 Jan;28(1):15-20

Hospital for Special Surgery, New York, New York, USA.

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January 2016

Current therapies for ANCA-associated vasculitis.

Annu Rev Med 2015 17;66:227-40. Epub 2014 Oct 17.

Department of Medicine/Division of Rheumatology, Hospital for Special Surgery, New York, NY 10021; email: ,

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September 2015

Nilotinib (Tasigna™) in the treatment of early diffuse systemic sclerosis: an open-label, pilot clinical trial.

Arthritis Res Ther 2015 Aug 18;17:213. Epub 2015 Aug 18.

Department of Rheumatology, Hospital for Special Surgery, 535 East 70th St, New York, NY, 10021, USA.

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August 2015

Current landscape of antineutrophil cytoplasmic antibody-associated vasculitis: classification, diagnosis, and treatment.

Rheum Dis Clin North Am 2015 ;41(1):1-19, vii

Division of Rheumatology, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USA.

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July 2015

Allosteric modulation of proteinase 3 activity by anti-neutrophil cytoplasmic antibodies in granulomatosis with polyangiitis.

J Autoimmun 2015 May 3;59:43-52. Epub 2015 Mar 3.

Comprehensive Pneumology Center, Institute of Lung Biology and Disease (iLBD), University Hospital, Ludwig Maximilians University and Helmholtz Zentrum München, Member of the German Center of Lung Research, Max-Lebsche-Platz 31, 81377 Munich, Germany; Max Planck Institute of Neurobiology, Planegg-Martinsried, Germany. Electronic address:

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May 2015

Pulmonary vasculitis.

Rheum Dis Clin North Am 2015 May 27;41(2):315-31. Epub 2015 Feb 27.

Division of Rheumatology, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USA.

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May 2015

Rituximab versus cyclophosphamide for ANCA-associated vasculitis with renal involvement.

J Am Soc Nephrol 2015 Apr 7;26(4):976-85. Epub 2014 Nov 7.

Division of Pulmonary and Critical Care Medicine and Division of Nephrology and Hypertension, Mayo Clinic College of Medicine, Rochester, Minnesota;

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April 2015

A large-scale genetic analysis reveals a strong contribution of the HLA class II region to giant cell arteritis susceptibility.

Am J Hum Genet 2015 Apr 26;96(4):565-80. Epub 2015 Mar 26.

Instituto de Parasitología y Biomedicina "López-Neyra," CSIC, PTS Granada, Granada 18016, Spain.

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April 2015

Increased rho kinase activity in temporal artery biopsies from patients with giant cell arteritis.

Rheumatology (Oxford) 2015 Mar 10;54(3):554-8. Epub 2014 Sep 10.

Department of Rheumatology, Hospital for Special Surgery, Department of Medicine, Weill-Cornell Medical College, Autoimmunity and Inflammation Program, Hospital for Special Surgery and Department of Clinical Pathology and Laboratory Medicine, Weill-Cornell Medical College, New York, NY, USA. Department of Rheumatology, Hospital for Special Surgery, Department of Medicine, Weill-Cornell Medical College, Autoimmunity and Inflammation Program, Hospital for Special Surgery and Department of Clinical Pathology and Laboratory Medicine, Weill-Cornell Medical College, New York, NY, USA.

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March 2015

Practice patterns of ANCA-associated vasculitis: exploring differences among subspecialties at a single academic medical centre.

Clin Exp Rheumatol 2014 May-Jun;32(3 Suppl 82):S48-50. Epub 2014 May 16.

Department of Rheumatology, Hospital for Special Surgery, New York, USA.

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July 2014

Biomarkers in ANCA-associated vasculitis.

Curr Rheumatol Rep 2013 Oct;15(10):363

Division of Rheumatology, Hospital for Special Surgery, 535 E. 70th Street, New York, NY 10021, USA.

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October 2013

Low prevalence of coeliac disease in patients with systemic sclerosis: a cross-sectional study of a registry cohort.

Rheumatology (Oxford) 2013 May 18;52(5):939-43. Epub 2013 Jan 18.

Department of Rheumatology, Hospital for Special Surgery, New York, NY, USA.

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May 2013

Design of the tocilizumab in giant cell arteritis trial.

Int J Rheumatol 2013 7;2013:912562. Epub 2013 Apr 7.

Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

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May 2013

Tyrosine Kinase Inhibitors in the Treatment of Systemic Sclerosis: The Difficulty in Interpreting Proof-of-Concept Studies.

Int J Rheumatol 2011 13;2011:842181. Epub 2011 Oct 13.

Department of Rheumatology, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USA.

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November 2011

Imatinib and the treatment of fibrosis: recent trials and tribulations.

Curr Rheumatol Rep 2011 Feb;13(1):51-8

Department of Rheumatology, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USA.

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February 2011

Targeting tyrosine kinases: a novel therapeutic strategy for systemic sclerosis.

Curr Opin Rheumatol 2010 Nov;22(6):690-5

Department of Rheumatology, Hospital for Special Surgery, New York 10021, USA.

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November 2010

Adjunctive methotrexate for treatment of giant cell arteritis: an individual patient data meta-analysis.

Arthritis Rheum 2007 Aug;56(8):2789-97

Vasculitis Center, Boston University School of Medicine, 75 Albany Street, Boston, MA 02118, USA.

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August 2007

Therapy for giant cell arteritis: can we do better?

Arthritis Rheum 2006 Oct;54(10):3071-4

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October 2006

Ehrlichiosis as a near-fatal cause of postoperative fever after bilateral total knee arthroplasty.

J Knee Surg 2006 Oct;19(4):273-5

Department of Orthopedic Surgery, Hospital for Special Surgery, New York, NY 10021, USA.

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October 2006

Newer therapeutic approaches to the vasculitides: biologic agents.

Rheum Dis Clin North Am 2006 Feb;32(1):187-200, xi

Hospital for Special Surgery, New York, NY 10021, USA.

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February 2006

Inflammatory disease in older adults. Cranial arteritis.

Geriatrics 2004 Dec;59(12):25-9; quiz 30

Albert Einstein College of Medicine, New York City, USA.

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December 2004

Inflammatory diseases in older adults: polymyalgia rheumatica.

Geriatrics 2004 Nov;59(11):39-43; quiz 44

Albert Einstein College of Medicine, New York City, NY, USA.

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November 2004

Ticlopidine-induced lupus: a report of 4 cases.

Arch Intern Med 2002 Oct;162(19):2240-3

Division of Rheumatology, Beth Israel Medical Center, 170 E End Ave, New York, NY 10128, USA.

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October 2002

Long-term outcome in lupus nephritis.

Ann Intern Med 2002 Sep;137(6):545-6; author reply 545-6

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September 2002