Robert Sebra

Robert Sebra

UNVERIFIED PROFILE

Are you Robert Sebra?   Register this Author

Register author
Robert Sebra

Robert Sebra

Publications by authors named "Robert Sebra"

Are you Robert Sebra?   Register this Author

98Publications

3260Reads

9Profile Views

In Reply: Retention of ATRX and DAXX Expression in Meningiomas.

Neurosurgery 2020 Feb;86(2):E244-E246

Department of Neurosurgery Icahn School of Medicine at Mount Sinai New York, New York.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/neuros/nyz504DOI Listing
February 2020

Elucidation of de novo small insertion/deletion biology with parent-of-origin phasing.

Hum Mutat 2020 Jan 3. Epub 2020 Jan 3.

Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, New York.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/humu.23971DOI Listing
January 2020

Genetic resilience to Alzheimer's disease in APOE ε4 homozygotes: A systematic review.

Alzheimers Dement 2019 Dec 7;15(12):1612-1623. Epub 2019 Sep 7.

Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jalz.2019.05.011DOI Listing
December 2019

Capture of complete ciliate chromosomes in single sequencing reads reveals widespread chromosome isoforms.

BMC Genomics 2019 Dec 30;20(1):1037. Epub 2019 Dec 30.

Departments of Biochemistry & Molecular Biophysics and Biological Sciences, Columbia University, New York, NY, 10032, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12864-019-6189-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937825PMC
December 2019

Reprioritization of biofilm metabolism is associated with nutrient adaptation and long-term survival of .

NPJ Biofilms Microbiomes 2019 5;5:33. Epub 2019 Nov 5.

1The Abigail Wexner Research Institute at Nationwide Children's Hospital, Center for Microbial Pathogenesis, 700 Children's Drive, Columbus, OH 43205 USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41522-019-0105-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831627PMC
November 2019

Mce3R Stress-Resistance Pathway Is Vulnerable to Small-Molecule Targeting That Improves Tuberculosis Drug Activities.

ACS Infect Dis 2019 Jul 3;5(7):1239-1251. Epub 2019 May 3.

Department of Chemistry , Stony Brook University , 100 John S. Toll Drive , Stony Brook , New York 11794-3400 , United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acsinfecdis.9b00099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630528PMC
July 2019

Provides a Window into Carbapenemase Gene Transfer, Plasmid Rearrangements, and Patient Interactions with the Hospital Environment.

Antimicrob Agents Chemother 2019 06 24;63(6). Epub 2019 May 24.

Modernizing Medical Microbiology Consortium, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/AAC.02513-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535554PMC
June 2019

Identification of a DNA N6-Adenine Methyltransferase Complex and Its Impact on Chromatin Organization.

Cell 2019 Jun 16;177(7):1781-1796.e25. Epub 2019 May 16.

Departments of Biochemistry & Molecular Biophysics and Biological Sciences, Columbia University, New York, NY 10032, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2019.04.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570567PMC
June 2019

High-coverage, long-read sequencing of Han Chinese trio reference samples.

Sci Data 2019 06 14;6(1):91. Epub 2019 Jun 14.

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, 1 Gustave L Levy Pl, New York, NY, 10029, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41597-019-0098-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572837PMC
June 2019

Don't overlook the little guy: An evaluation of the frequency of small plasmids co-conjugating with larger carbapenemase gene containing plasmids.

Plasmid 2019 05 27;103:1-8. Epub 2019 Mar 27.

Division of Infectious Disease and International Health, Department of Medicine, University of Virginia Health System, Charlottesville, VA, USA; Clinical Microbiology Laboratory, Department of Pathology, University of Virginia Health System, Charlottesville, VA, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.plasmid.2019.03.005DOI Listing
May 2019

Microevolution in response to transient heme-iron restriction enhances intracellular bacterial community development and persistence.

PLoS Pathog 2018 10 17;14(10):e1007355. Epub 2018 Oct 17.

The Research Institute at Nationwide Children's Hospital, Center for Microbial Pathogenesis, Columbus, Ohio, United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.ppat.1007355DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205647PMC
October 2018

Characterization of drug-induced splicing complexity in prostate cancer cell line using long read technology.

Pac Symp Biocomput 2018 ;23:8-19

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, 1425 Madison Ave, New York, NY 10029, USA.

View Article

Download full-text PDF

Source
August 2018

High-density single cell mRNA sequencing to characterize circulating tumor cells in hepatocellular carcinoma.

Sci Rep 2018 08 1;8(1):11570. Epub 2018 Aug 1.

Division of Liver Diseases, Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-018-30047-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070499PMC
August 2018

Mapping and characterizing N6-methyladenine in eukaryotic genomes using single-molecule real-time sequencing.

Genome Res 2018 07 15;28(7):1067-1078. Epub 2018 May 15.

Department of Genetics and Genomic Sciences and Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gr.231068.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028124PMC
July 2018

Genetic Basis of Emerging Vancomycin, Linezolid, and Daptomycin Heteroresistance in a Case of Persistent Enterococcus faecium Bacteremia.

Antimicrob Agents Chemother 2018 04 27;62(4). Epub 2018 Mar 27.

Icahn Institute for Genomics and Multiscale Biology, Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/AAC.02007-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913925PMC
April 2018

Metagenomic binning and association of plasmids with bacterial host genomes using DNA methylation.

Nat Biotechnol 2018 01 11;36(1):61-69. Epub 2017 Dec 11.

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nbt.4037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762413PMC
January 2018

Treatment-associated DNA-binding domain missense mutations in the pathogenesis of secondary gliosarcoma.

Oncotarget 2018 Jan 20;9(2):2603-2621. Epub 2017 Dec 20.

Departments of Neurosurgery and Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

View Article

Download full-text PDF

Source
http://www.oncotarget.com/fulltext/23517
Publisher Site
http://dx.doi.org/10.18632/oncotarget.23517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788663PMC
January 2018

DNA sequencing at ultra-high fidelity.

Authors:
Robert Sebra

Nat Biotechnol 2017 12 30;35(12):1143-1144. Epub 2017 Oct 30.

Department of Genetics & Genomic Sciences & Icahn Institute for Genomics & Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, USA, and at Sema4, a Mount Sinai venture, Stamford, Connecticut, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nbt.4001DOI Listing
December 2017

Using single-cell multiple omics approaches to resolve tumor heterogeneity.

Clin Transl Med 2017 Dec 28;6(1):46. Epub 2017 Dec 28.

Cancer Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s40169-017-0177-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746494PMC
December 2017

Identification of Differentially Expressed Splice Variants by the Proteogenomic Pipeline Splicify.

Mol Cell Proteomics 2017 10 26;16(10):1850-1863. Epub 2017 Jul 26.

From the ‡Translational Gastrointestinal Oncology, Department of Pathology, Netherlands Cancer Institute, Amsterdam, the Netherlands;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/mcp.TIR117.000056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629268PMC
October 2017

Prospective Isolation and Comparison of Human Germinal Matrix and Glioblastoma EGFR Populations with Stem Cell Properties.

Stem Cell Reports 2017 05 20;8(5):1421-1429. Epub 2017 Apr 20.

Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Neuroscience, Friedman Brain Institute, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.stemcr.2017.03.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425658PMC
May 2017

Chromosomal Integration of the Klebsiella pneumoniae Carbapenemase Gene, , in Klebsiella Species Is Elusive but Not Rare.

Antimicrob Agents Chemother 2017 03 23;61(3). Epub 2017 Feb 23.

Modernizing Medical Microbiology Consortium, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/AAC.01823-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328509PMC
March 2017

Genome-Wide Biases in the Rate and Molecular Spectrum of Spontaneous Mutations in Vibrio cholerae and Vibrio fischeri.

Mol Biol Evol 2017 01 15;34(1):93-109. Epub 2016 Oct 15.

Microbiology Graduate Program, University of New Hampshire, Durham, NH

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/molbev/msw224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854121PMC
January 2017

Capturing pairwise and multi-way chromosomal conformations using chromosomal walks.

Nature 2016 12 30;540(7632):296-300. Epub 2016 Nov 30.

Department of Computer Science and Applied Mathematics and Department of Biological Regulation, Weizmann Institute, Rehovot 76100, Israel.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature20158DOI Listing
December 2016

Complete Sequencing of Plasmids Containing blaOXA-163 and blaOXA-48 in Escherichia coli Sequence Type 131.

Antimicrob Agents Chemother 2016 11 21;60(11):6948-6951. Epub 2016 Oct 21.

Division of Microbiology, Calgary Laboratory Services, Calgary, Alberta, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/AAC.01130-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075115PMC
November 2016

First Report of blaIMP-14 on a Plasmid Harboring Multiple Drug Resistance Genes in Escherichia coli Sequence Type 131.

Antimicrob Agents Chemother 2016 08 22;60(8):5068-71. Epub 2016 Jul 22.

Division of Microbiology, Calgary Laboratory Services, Calgary, Alberta, Canada Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, Alberta, Canada Department of Microbiology, Immunology, and Infectious Diseases, University of Calgary, Calgary, Alberta, Canada Snyder Institute for Chronic Diseases, University of Calgary, Calgary, Alberta, Canada Department of Medical Microbiology, University of Pretoria, Pretoria, South Africa.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/AAC.00840-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958194PMC
August 2016

Nested Russian Doll-Like Genetic Mobility Drives Rapid Dissemination of the Carbapenem Resistance Gene blaKPC.

Antimicrob Agents Chemother 2016 06 23;60(6):3767-78. Epub 2016 May 23.

Division of Infectious Diseases and International Health, Department of Medicine, University of Virginia Health System, Charlottesville, Virginia, USA Clinical Microbiology, Department of Pathology, University of Virginia Health System, Charlottesville, Virginia, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/AAC.00464-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879409PMC
June 2016

Long-Read Single Molecule Real-Time Full Gene Sequencing of Cytochrome P450-2D6.

Hum Mutat 2016 Mar 18;37(3):315-23. Epub 2015 Dec 18.

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, 10029.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/humu.22936DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752389PMC
March 2016

Complete Genome Sequence of KPC-Producing Klebsiella pneumoniae Strain CAV1193.

Genome Announc 2016 Jan 28;4(1). Epub 2016 Jan 28.

Division of Infectious Diseases and International Health, Department of Medicine, University of Virginia Health System, Charlottesville, Virginia, USA Clinical Microbiology, Department of Pathology, University of Virginia Health System, Charlottesville, Virginia, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/genomeA.01649-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732343PMC
January 2016

Parallel Epidemics of Community-Associated Methicillin-Resistant Staphylococcus aureus USA300 Infection in North and South America.

J Infect Dis 2015 Dec 5;212(12):1874-82. Epub 2015 Jun 5.

Division of Infectious Diseases, Department of Internal Medicine Department of Microbiology and Molecular Genetics, University of Texas Medical School at Houston Molecular Genetics and Antimicrobial Resistance Unit, International Center for Microbial Genomics, Universidad El Bosque, Bogotá, Colombia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/infdis/jiv320DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655856PMC
December 2015

The PsychENCODE project.

Nat Neurosci 2015 Dec;18(12):1707-12

Yale University, New Haven, Connecticut, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nn.4156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675669PMC
December 2015

An integrated map of structural variation in 2,504 human genomes.

Nature 2015 Oct;526(7571):75-81

European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Meyerhofstr. 1, 69117 Heidelberg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature15394DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617611PMC
October 2015

Single molecule-level detection and long read-based phasing of epigenetic variations in bacterial methylomes.

Nat Commun 2015 Jun 15;6:7438. Epub 2015 Jun 15.

Department of Genetics and Genomic Sciences and Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York 10029, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms8438DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490391PMC
June 2015

Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae at a single institution: insights into endemicity from whole-genome sequencing.

Antimicrob Agents Chemother 2015 Mar 5;59(3):1656-63. Epub 2015 Jan 5.

Division of Infectious Diseases and International Health, Department of Medicine, University of Virginia Health System, Charlottesville, Virginia, USA Office of Hospital Epidemiology, University of Virginia Health System, Charlottesville, Virginia, USA.

View Article

Download full-text PDF

Source
http://aac.asm.org/lookup/doi/10.1128/AAC.04292-14
Publisher Site
http://dx.doi.org/10.1128/AAC.04292-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325807PMC
March 2015

Evolution of hypervirulence by a MRSA clone through acquisition of a transposable element.

Mol Microbiol 2014 Aug 16;93(4):664-81. Epub 2014 Jul 16.

Department of Microbiology, New York University School of Medicine, New York, NY, USA; Division of Infectious Diseases, Boston Children's Hospital, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/mmi.12682DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4127135PMC
August 2014

Controlled polymerization chemistry to graft architectures that influence cell-material interactions.

Acta Biomater 2007 Mar 22;3(2):151-61. Epub 2007 Jan 22.

Department of Chemical and Biological Engineering, ECCH 111, CB424, University of Colorado, Boulder, CO 80309-0424, United States.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S174270610600097
Publisher Site
http://dx.doi.org/10.1016/j.actbio.2006.07.010DOI Listing
March 2007

Detection of antigens in biologically complex fluids with photografted whole antibodies.

Anal Chem 2006 May;78(9):3144-51

Department of Chemical and Biological Engineering and Howard Hughes Medical Institute, University of Colorado, Boulder, Colorado 80309, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/ac052246yDOI Listing
May 2006

Robust polymer microfluidic device fabrication via contact liquid photolithographic polymerization (CLiPP).

Lab Chip 2004 Dec 24;4(6):658-62. Epub 2004 Sep 24.

Department of Chemical and Biological Engineering, University of Colorado, Boulder, CO 80309-0424, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/b405985aDOI Listing
December 2004