Robert Sauerwein

Robert Sauerwein

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Robert Sauerwein

Publications by authors named "Robert Sauerwein"

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Fast and fierce versus slow and smooth: Heterogeneity in immune responses to Plasmodium in the controlled human malaria infection model.

Immunol Rev 2019 Oct 12. Epub 2019 Oct 12.

Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1111/imr.12811DOI Listing
October 2019

Transforming growth factor-beta profiles correlate with clinical symptoms and parameters of haemostasis and inflammation in a controlled human malaria infection.

Cytokine 2019 Sep 13;125:154838. Epub 2019 Sep 13.

Department of Medical Microbiology & Infectious Diseases, Erasmus MC University Medical Center, Rotterdam 3015 GD, the Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10434666193026
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http://dx.doi.org/10.1016/j.cyto.2019.154838DOI Listing
September 2019

Whole-blood transcriptomic signatures induced during immunization by chloroquine prophylaxis and Plasmodium falciparum sporozoites.

Sci Rep 2019 Jun 10;9(1):8386. Epub 2019 Jun 10.

Department of Medical Microbiology and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/s41598-019-44924-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557840PMC
June 2019

T1-Polarized T Cells Delay Naturally-Acquired Immunity to Malaria.

Front Immunol 2019 17;10:1096. Epub 2019 May 17.

Department of Medical Microbiology, RadboudUMC Centre for Infectious Diseases, Nijmegen, Netherlands.

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http://dx.doi.org/10.3389/fimmu.2019.01096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533880PMC
May 2019

Can Patrolling Liver-Resident T Cells Control Human Malaria Parasite Development?

Trends Immunol 2019 03 31;40(3):186-196. Epub 2019 Jan 31.

Department of Medical Microbiology, Radboud University Medical Center, PO Box 9101, 6500 HB, Nijmegen, The Netherlands; Radboud Center for Infectious Diseases, Radboud University Medical Center, PO Box 9101, 6500 HB, Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.it.2019.01.002DOI Listing
March 2019

Two-Faced Immunity? The Evidence for Antibody Enhancement of Malaria Transmission.

Trends Parasitol 2019 02 17;35(2):140-153. Epub 2018 Dec 17.

Department of Immunology and Infection, London School of Hygiene and Tropical Medicine, Keppel Street, London, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S14714922183024
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http://dx.doi.org/10.1016/j.pt.2018.11.003DOI Listing
February 2019

Mosquito Infectivity and Parasitemia after Controlled Human Malaria Infection.

Am J Trop Med Hyg 2018 06 26;98(6):1705-1708. Epub 2018 Apr 26.

Department of Pediatrics, Radboud Institute for Molecular Life Sciences, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.4269/ajtmh.17-0952DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086182PMC
June 2018

A Macrophage Colony-Stimulating-Factor-Producing γδ T Cell Subset Prevents Malarial Parasitemic Recurrence.

Immunity 2018 02 6;48(2):350-363.e7. Epub 2018 Feb 6.

Institute for Immunity, Transplantation and Infection, Stanford University, Stanford, CA 94305, USA; Department of Microbiology and Immunology, Stanford University, Stanford, CA 94305, USA; Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2018.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956914PMC
February 2018

Proguanil and cycloguanil are organic cation transporter and multidrug and toxin extrusion substrates.

Malar J 2017 10 23;16(1):422. Epub 2017 Oct 23.

Department of Pharmacology and Toxicology, Radboud University Medical Center, Geert Grooteplein 28, 6525 GA, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1186/s12936-017-2062-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654082PMC
October 2017

Towards clinical development of a Pfs48/45-based transmission blocking malaria vaccine.

Expert Rev Vaccines 2017 04 9;16(4):329-336. Epub 2017 Jan 9.

d Department of Medical Microbiology , Radboud University Medical Center , Nijmegen , The Netherlands.

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http://dx.doi.org/10.1080/14760584.2017.1276833DOI Listing
April 2017

The Power of Malaria Vaccine Trials Using Controlled Human Malaria Infection.

PLoS Comput Biol 2017 01 12;13(1):e1005255. Epub 2017 Jan 12.

Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1371/journal.pcbi.1005255DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5230743PMC
January 2017

Erratum to: Diagnosis and treatment based on quantitative PCR after controlled human malaria infection.

Malar J 2016 28;15:522. Epub 2016 Oct 28.

Department of Medical Microbiology and Radboud Center for Infectious Diseases, Radboud University Medical Center, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1186/s12936-016-1571-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084327PMC
October 2016

[The first malaria vaccine: a significant milestone].

Ned Tijdschr Geneeskd 2015 ;159:A9730

Radboudumc, afd. Medische Microbiologie, Nijmegen.

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September 2016

Diagnosis and treatment based on quantitative PCR after controlled human malaria infection.

Malar J 2016 08 5;15(1):398. Epub 2016 Aug 5.

Department of Medical Microbiology and Radboud Center for Infectious Diseases, Radboud university medical center, PO Box 9101, 6500 HB, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1186/s12936-016-1434-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974752PMC
August 2016

Assessment of Parasite Liver-Stage Burden in Human-Liver Chimeric Mice.

Methods Mol Biol 2015 ;1325:59-68

Center for Vaccinology, Ghent University and University Hospital, De Pintelaan 185, Ghent, 9000, Belgium.

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http://dx.doi.org/10.1007/978-1-4939-2815-6_5DOI Listing
July 2016

Synthetic TLR4 agonists enhance functional antibodies and CD4+ T-cell responses against the Plasmodium falciparum GMZ2.6C multi-stage vaccine antigen.

Vaccine 2016 Apr 17;34(19):2207-15. Epub 2016 Mar 17.

Department for Congenital Disorders, Statens Serum Institute, Copenhagen, Denmark; Centre for Medical Parasitology at Department of International Health, Immunology and Microbiology, University of Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2016.03.016DOI Listing
April 2016

Immune activation and induction of memory: lessons learned from controlled human malaria infection with Plasmodium falciparum.

Parasitology 2016 Feb;143(2):224-35

Department of Medical Microbiology,Radboud university medical center,P.O. Box 9101,6500 HB Nijmegen,The Netherlands.

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http://dx.doi.org/10.1017/S0031182015000761DOI Listing
February 2016

MRP1 mediates folate transport and antifolate sensitivity in Plasmodium falciparum.

FEBS Lett 2016 Feb 17;590(4):482-92. Epub 2016 Feb 17.

Department of Pharmacology and Toxicology, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1002/1873-3468.12079DOI Listing
February 2016

Dynamics of the Human Infectious Reservoir for Malaria Determined by Mosquito Feeding Assays and Ultrasensitive Malaria Diagnosis in Burkina Faso.

J Infect Dis 2016 Jan 3;213(1):90-9. Epub 2015 Jul 3.

Department of Immunology and Infection, London School of Hygiene and Tropical Medicine, United Kingdom Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1093/infdis/jiv370DOI Listing
January 2016

Cross-stage immunity for malaria vaccine development.

Vaccine 2015 Dec 19;33(52):7513-7. Epub 2015 Oct 19.

Mill Hill Laboratory, The Francis Crick Institute, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2015.09.098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687527PMC
December 2015

Assessing the impact of next-generation rapid diagnostic tests on Plasmodium falciparum malaria elimination strategies.

Nature 2015 Dec;528(7580):S94-101

MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, Norfolk Place, London W2 1PG, UK.

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http://dx.doi.org/10.1038/nature16040DOI Listing
December 2015

Spatial Patterns of Plasmodium falciparum Clinical Incidence, Asymptomatic Parasite Carriage and Anopheles Density in Two Villages in Mali.

Am J Trop Med Hyg 2015 Oct 31;93(4):790-7. Epub 2015 Aug 31.

Department of Epidemiology of Parasitic Disease, Faculty of Medicine and Dentistry, Malaria Research and Training Center, University of Sciences, Techniques and Technologies of Bamako, Mali; Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, the Netherlands; Department of Immunology and Infection, London School of Hygiene and Tropical Medicine, London, United Kingdom; Aix-Marseille University, Marseille, France; ConsultingWhere, Redbourn, St. Albans, United Kingdom; Laboratory of Entomology, Wageningen University and Research Center, Wageningen, The Netherlands.

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http://dx.doi.org/10.4269/ajtmh.14-0765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596601PMC
October 2015

Novel pantothenate derivatives for anti-malarial chemotherapy.

Malar J 2015 Apr 18;14:169. Epub 2015 Apr 18.

Department of Dermatology and Radboud Institute for Molecular Life Sciences, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1186/s12936-015-0673-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425855PMC
April 2015

Studying the effect of chloroquine on sporozoite-induced protection and immune responses in Plasmodium berghei malaria.

Malar J 2015 Mar 26;14:130. Epub 2015 Mar 26.

Department of Medical Microbiology, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1186/s12936-015-0626-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389414PMC
March 2015