Publications by authors named "Robert Sauerwein"

100Publications

Third human challenge trial conference, Oxford, United Kingdom, February 6-7, 2020, a meeting report.

Biologicals 2020 Jul 4;66:41-52. Epub 2020 Jun 4.

International Alliance for Biological Standardization, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.biologicals.2020.04.004DOI Listing
July 2020

Activatory Receptor NKp30 Predicts NK Cell Activation During Controlled Human Malaria Infection.

Front Immunol 2019 10;10:2864. Epub 2019 Dec 10.

Department of Medical Microbiology and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, Netherlands.

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http://dx.doi.org/10.3389/fimmu.2019.02864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916516PMC
December 2019

Fast and fierce versus slow and smooth: Heterogeneity in immune responses to Plasmodium in the controlled human malaria infection model.

Immunol Rev 2020 01 12;293(1):253-269. Epub 2019 Oct 12.

Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1111/imr.12811DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973142PMC
January 2020

Whole-blood transcriptomic signatures induced during immunization by chloroquine prophylaxis and Plasmodium falciparum sporozoites.

Sci Rep 2019 06 10;9(1):8386. Epub 2019 Jun 10.

Department of Medical Microbiology and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/s41598-019-44924-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557840PMC
June 2019

T1-Polarized T Cells Delay Naturally-Acquired Immunity to Malaria.

Front Immunol 2019 17;10:1096. Epub 2019 May 17.

Department of Medical Microbiology, RadboudUMC Centre for Infectious Diseases, Nijmegen, Netherlands.

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http://dx.doi.org/10.3389/fimmu.2019.01096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533880PMC
June 2020

Can Patrolling Liver-Resident T Cells Control Human Malaria Parasite Development?

Trends Immunol 2019 03 31;40(3):186-196. Epub 2019 Jan 31.

Department of Medical Microbiology, Radboud University Medical Center, PO Box 9101, 6500 HB, Nijmegen, The Netherlands; Radboud Center for Infectious Diseases, Radboud University Medical Center, PO Box 9101, 6500 HB, Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.it.2019.01.002DOI Listing
March 2019

Two-Faced Immunity? The Evidence for Antibody Enhancement of Malaria Transmission.

Trends Parasitol 2019 02 17;35(2):140-153. Epub 2018 Dec 17.

Department of Immunology and Infection, London School of Hygiene and Tropical Medicine, Keppel Street, London, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S14714922183024
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http://dx.doi.org/10.1016/j.pt.2018.11.003DOI Listing
February 2019

Mosquito Infectivity and Parasitemia after Controlled Human Malaria Infection.

Am J Trop Med Hyg 2018 06 26;98(6):1705-1708. Epub 2018 Apr 26.

Department of Pediatrics, Radboud Institute for Molecular Life Sciences, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.4269/ajtmh.17-0952DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086182PMC
June 2018

A Macrophage Colony-Stimulating-Factor-Producing γδ T Cell Subset Prevents Malarial Parasitemic Recurrence.

Immunity 2018 02 6;48(2):350-363.e7. Epub 2018 Feb 6.

Institute for Immunity, Transplantation and Infection, Stanford University, Stanford, CA 94305, USA; Department of Microbiology and Immunology, Stanford University, Stanford, CA 94305, USA; Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2018.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956914PMC
February 2018

Proguanil and cycloguanil are organic cation transporter and multidrug and toxin extrusion substrates.

Malar J 2017 10 23;16(1):422. Epub 2017 Oct 23.

Department of Pharmacology and Toxicology, Radboud University Medical Center, Geert Grooteplein 28, 6525 GA, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1186/s12936-017-2062-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654082PMC
October 2017

The Power of Malaria Vaccine Trials Using Controlled Human Malaria Infection.

PLoS Comput Biol 2017 01 12;13(1):e1005255. Epub 2017 Jan 12.

Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1371/journal.pcbi.1005255DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5230743PMC
January 2017

Towards clinical development of a Pfs48/45-based transmission blocking malaria vaccine.

Expert Rev Vaccines 2017 04 9;16(4):329-336. Epub 2017 Jan 9.

d Department of Medical Microbiology , Radboud University Medical Center , Nijmegen , The Netherlands.

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http://dx.doi.org/10.1080/14760584.2017.1276833DOI Listing
April 2017

Erratum to: Diagnosis and treatment based on quantitative PCR after controlled human malaria infection.

Malar J 2016 28;15:522. Epub 2016 Oct 28.

Department of Medical Microbiology and Radboud Center for Infectious Diseases, Radboud University Medical Center, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1186/s12936-016-1571-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084327PMC
October 2016

Diagnosis and treatment based on quantitative PCR after controlled human malaria infection.

Malar J 2016 08 5;15(1):398. Epub 2016 Aug 5.

Department of Medical Microbiology and Radboud Center for Infectious Diseases, Radboud university medical center, PO Box 9101, 6500 HB, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1186/s12936-016-1434-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974752PMC
August 2016

Synthetic TLR4 agonists enhance functional antibodies and CD4+ T-cell responses against the Plasmodium falciparum GMZ2.6C multi-stage vaccine antigen.

Vaccine 2016 Apr 17;34(19):2207-15. Epub 2016 Mar 17.

Department for Congenital Disorders, Statens Serum Institute, Copenhagen, Denmark; Centre for Medical Parasitology at Department of International Health, Immunology and Microbiology, University of Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2016.03.016DOI Listing
April 2016

MRP1 mediates folate transport and antifolate sensitivity in Plasmodium falciparum.

FEBS Lett 2016 Feb 17;590(4):482-92. Epub 2016 Feb 17.

Department of Pharmacology and Toxicology, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1002/1873-3468.12079DOI Listing
February 2016

Immune activation and induction of memory: lessons learned from controlled human malaria infection with Plasmodium falciparum.

Parasitology 2016 Feb;143(2):224-35

Department of Medical Microbiology,Radboud university medical center,P.O. Box 9101,6500 HB Nijmegen,The Netherlands.

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http://dx.doi.org/10.1017/S0031182015000761DOI Listing
February 2016

[The first malaria vaccine: a significant milestone].

Ned Tijdschr Geneeskd 2015 ;159:A9730

Radboudumc, afd. Medische Microbiologie, Nijmegen.

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September 2016

Assessing the impact of next-generation rapid diagnostic tests on Plasmodium falciparum malaria elimination strategies.

Nature 2015 Dec;528(7580):S94-101

MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, Norfolk Place, London W2 1PG, UK.

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http://dx.doi.org/10.1038/nature16040DOI Listing
December 2015

Cross-stage immunity for malaria vaccine development.

Vaccine 2015 Dec 19;33(52):7513-7. Epub 2015 Oct 19.

Mill Hill Laboratory, The Francis Crick Institute, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2015.09.098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687527PMC
December 2015

Assessment of Parasite Liver-Stage Burden in Human-Liver Chimeric Mice.

Methods Mol Biol 2015 ;1325:59-68

Center for Vaccinology, Ghent University and University Hospital, De Pintelaan 185, Ghent, 9000, Belgium.

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http://dx.doi.org/10.1007/978-1-4939-2815-6_5DOI Listing
July 2016