Robert S B Clark

Robert S B Clark

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Robert S B Clark

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DNA Viremia Is Associated with Hyperferritinemia in Pediatric Sepsis.

J Pediatr 2019 Oct 11;213:82-87.e2. Epub 2019 Jul 11.

Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA.

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http://dx.doi.org/10.1016/j.jpeds.2019.06.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765425PMC
October 2019

Opioid e-prescribing trends at discharge in a large pediatric health system.

J Opioid Manag 2019 Mar/Apr;15(2):119-127

Department of Critical Care Medicine and the Brain Care Institute, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania; Safar Center for Resuscitation Research, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.5055/jom.2019.0493DOI Listing
September 2019

Association of Severe Hyperoxemia Events and Mortality Among Patients Admitted to a Pediatric Intensive Care Unit.

JAMA Netw Open 2019 Aug 2;2(8):e199812. Epub 2019 Aug 2.

Department of Pediatrics, University of Pittsburgh School of Medicine; UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania.

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https://jamanetwork.com/journals/jamanetworkopen/fullarticle
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http://dx.doi.org/10.1001/jamanetworkopen.2019.9812DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707098PMC
August 2019

Membrane transporters in traumatic brain injury: Pathological, pharmacotherapeutic, and developmental implications.

Exp Neurol 2019 Jul 21;317:10-21. Epub 2019 Feb 21.

Center for Clinical Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, PA, United States of America; Safar Center for Resuscitation Research, University of Pittsburgh, Pittsburgh, PA, United States of America. Electronic address:

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http://dx.doi.org/10.1016/j.expneurol.2019.02.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544476PMC
July 2019

C-Reactive Protein and Ferritin Are Associated With Organ Dysfunction and Mortality in Hospitalized Children.

Clin Pediatr (Phila) 2019 Jun 31;58(7):752-760. Epub 2019 Mar 31.

1 Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1177/0009922819837352DOI Listing
June 2019

Detection of brain specific cardiolipins in plasma after experimental pediatric head injury.

Exp Neurol 2019 Jun 11;316:63-73. Epub 2019 Apr 11.

Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA; Safar Center for Resuscitation Research, University of Pittsburgh, Pittsburgh, PA, USA; Center for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, PA, USA; Children's Neuroscience Institute, Children's Hospital of Pittsburgh, Pittsburgh, PA, USA; Department of Environmental and Occupational Health, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00144886193006
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http://dx.doi.org/10.1016/j.expneurol.2019.04.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6622170PMC
June 2019

Factors Contributing to Fentanyl Pharmacokinetic Variability Among Diagnostically Diverse Critically Ill Children.

Clin Pharmacokinet 2019 Jun 6. Epub 2019 Jun 6.

Safar Center for Resuscitation Research, University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1007/s40262-019-00773-1DOI Listing
June 2019

The role of autophagy in acute brain injury: A state of flux?

Neurobiol Dis 2019 02 26;122:9-15. Epub 2018 Apr 26.

Department of Critical Care Medicine, Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, 4401 Penn Avenue, Pittsburgh, PA 15224, USA; Department of Pediatrics, University of Pittsburgh School of Medicine, 4401 Penn Avenue, Pittsburgh, PA 15224, USA; Brain Care Institute, Children's Hospital of Pittsburgh, 4401 Penn Avenue, Pittsburgh, PA 15224, USA. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2018.04.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203674PMC
February 2019

Aiming for the target: Mitochondrial drug delivery in traumatic brain injury.

Neuropharmacology 2019 02 30;145(Pt B):209-219. Epub 2018 Jul 30.

Department of Critical Care Medicine, Safar Center for Resuscitation Research, Children's Hospital of Pittsburgh, Pittsburgh, PA, USA; Department of Environmental and Occupational Health, Center for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, PA, USA; Children's Neuroscience Institute, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2018.07.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309489PMC
February 2019

Quantitative and qualitative assessment of glymphatic flux using Evans blue albumin.

J Neurosci Methods 2019 Jan 5;311:436-441. Epub 2018 Oct 5.

Department of Critical Care Medicine, Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, John G. Rangos Research Center - 6th Floor, 4401 Penn Avenue, Pittsburgh, Pennsylvania, 15224, USA; Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, 4401 Penn Avenue, Pittsburgh, Pennsylvania, 15224, USA; Children's Neuroscience Institute, UPMC Children's Hospital of Pittsburgh, 4401 Penn Avenue, Pittsburgh, Pennsylvania, 15224, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01650270183029
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http://dx.doi.org/10.1016/j.jneumeth.2018.09.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258322PMC
January 2019

Regionally clustered polymorphisms in a prospective cohort predict cerebral oedema and outcome in severe traumatic brain injury.

J Neurol Neurosurg Psychiatry 2018 11 19;89(11):1152-1162. Epub 2018 Apr 19.

Clinical and Translational Science Institute, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1136/jnnp-2017-317741DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181785PMC
November 2018

Synthesis and Evaluation of a Mitochondria-Targeting Poly(ADP-ribose) Polymerase-1 Inhibitor.

ACS Chem Biol 2018 10 14;13(10):2868-2879. Epub 2018 Sep 14.

Department of Critical Care Medicine, Safar Center for Resuscitation Research , University of Pittsburgh School of Medicine , Pittsburgh , Pennsylvania 15260 , United States.

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http://dx.doi.org/10.1021/acschembio.8b00423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402482PMC
October 2018

Long-Term Deficits in Cortical Circuit Function after Asphyxial Cardiac Arrest and Resuscitation in Developing Rats.

eNeuro 2017 May-Jun;4(3). Epub 2017 Jun 30.

Department of Pediatrics, Washington University in St. Louis School of Medicine, St. Louis, MO 63110.

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http://dx.doi.org/10.1523/ENEURO.0319-16.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492685PMC
September 2018

Exploratory Application of Neuropharmacometabolomics in Severe Childhood Traumatic Brain Injury.

Crit Care Med 2018 09;46(9):1471-1479

Clinical and Translational Science Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA.

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http://dx.doi.org/10.1097/CCM.0000000000003203DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095742PMC
September 2018

24 vs. 72 hours of hypothermia for pediatric cardiac arrest: A pilot, randomized controlled trial.

Resuscitation 2018 05 14;126:14-20. Epub 2018 Feb 14.

Critical Care Medicine, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, USA; Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, USA; Safar Center for Resuscitation Research, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1016/j.resuscitation.2018.02.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899619PMC
May 2018

Detecting and Quantifying pADPr In Vivo.

Methods Mol Biol 2017 ;1608:27-43

Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1007/978-1-4939-6993-7_3DOI Listing
April 2018

Brain-Specific Serum Biomarkers Predict Neurological Morbidity in Diagnostically Diverse Pediatric Intensive Care Unit Patients.

Neurocrit Care 2018 02;28(1):26-34

Departments of Critical Care Medicine, Safar Center for Resuscitation Research and the Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh Medical Center, 4401 Penn Avenue, Faculty Pavilion, Suite 2000, Pittsburgh, PA, 15224, USA.

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http://dx.doi.org/10.1007/s12028-017-0414-7DOI Listing
February 2018

Combined Neurotrauma Models: Experimental Models Combining Traumatic Brain Injury and Secondary Insults.

Methods Mol Biol 2016 ;1462:393-411

Department of Critical Care Medicine, Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh School of Medicine, 4401 Penn Avenue, Pittsburgh, PA, 15224, USA.

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http://dx.doi.org/10.1007/978-1-4939-3816-2_22DOI Listing
January 2018

ABCG2 c.421C>A Is Associated with Outcomes after Severe Traumatic Brain Injury.

J Neurotrauma 2018 01 19;35(1):48-53. Epub 2017 Sep 19.

6 Safar Center for Resuscitation Research, University of Pittsburgh , Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1089/neu.2017.5000DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757075PMC
January 2018

Paediatric traumatic brain injury: prognostic insights and outlooks.

Curr Opin Neurol 2017 Dec;30(6):565-572

aDepartment of Critical Care Medicine bDepartment of Pediatrics, Safar Center for Resuscitation Research and the Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1097/WCO.0000000000000504DOI Listing
December 2017

Healthcare in the PICU May Be More Complicated Than We Thought-Who Knew?

Pediatr Crit Care Med 2017 12;18(12):1188-1189

Departments of Critical Care Medicine and Pediatrics, Healthcare Informatics & Clinical Effectiveness, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA Departments of Critical Care Medicine and Pediatrics, Safar Center for Resuscitation Research, Brain Care Institute Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA.

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http://dx.doi.org/10.1097/PCC.0000000000001356DOI Listing
December 2017

Pre-clinical models in pediatric traumatic brain injury-challenges and lessons learned.

Childs Nerv Syst 2017 Oct 6;33(10):1693-1701. Epub 2017 Sep 6.

Safar Center for Resuscitation Research, Children's Hospital of Pittsburgh of UPMC, 4401 Penn Ave, Pittsburgh, PA, 15224, USA.

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http://dx.doi.org/10.1007/s00381-017-3474-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909721PMC
October 2017

Cerebrospinal Fluid NLRP3 is Increased After Severe Traumatic Brain Injury in Infants and Children.

Neurocrit Care 2017 Aug;27(1):44-50

Department of Critical Care Medicine, Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh School of Medicine, 4401 Penn Avenue, Pittsburgh, PA, 15224, USA.

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http://dx.doi.org/10.1007/s12028-017-0378-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680164PMC
August 2017

Alterations in Cerebral Blood Flow after Resuscitation from Cardiac Arrest.

Front Pediatr 2017 16;5:174. Epub 2017 Aug 16.

Safar Center for Resuscitation Research, Department of Pediatrics, University of Pittsburgh, Pittsburgh, PA, United States.

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http://journal.frontiersin.org/article/10.3389/fped.2017.001
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http://dx.doi.org/10.3389/fped.2017.00174DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561008PMC
August 2017

ABCB1 genotype is associated with fentanyl requirements in critically ill children.

Pediatr Res 2017 07 31;82(1):29-35. Epub 2017 May 31.

Department of Critical Care Medicine and Pediatrics, Safar Center for Resuscitation Research and the Brain Care Institute at the Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1038/pr.2017.103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509475PMC
July 2017

Autophagy Biomarkers Beclin 1 and p62 are Increased in Cerebrospinal Fluid after Traumatic Brain Injury.

Neurocrit Care 2017 Jun;26(3):348-355

Department of Critical Care Medicine, Safar Center for Resuscitation Research and the Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh Medical Center, 4401 Penn Avenue, Faculty Pavilion, Suite 2000, Pittsburgh, PA, 15224, USA.

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http://dx.doi.org/10.1007/s12028-016-0351-xDOI Listing
June 2017

Dietary Supplementation With Nonfermentable Fiber Alters the Gut Microbiota and Confers Protection in Murine Models of Sepsis.

Crit Care Med 2017 May;45(5):e516-e523

1Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA. 2Division of Pediatric General and Thoracic Surgery, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA. 3Department of Critical Care Medicine, University of Pittsburgh School of Medicine; Pittsburgh, PA. 4Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA 5Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA.

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http://dx.doi.org/10.1097/CCM.0000000000002291DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392159PMC
May 2017

Probenecid, an organic anion transporter 1 and 3 inhibitor, increases plasma and brain exposure of N-acetylcysteine.

Xenobiotica 2017 Apr 9;47(4):346-353. Epub 2016 Jun 9.

b Department of Pharmacy and Therapeutics , Center for Clinical Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh , PA , USA.

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http://dx.doi.org/10.1080/00498254.2016.1187777DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572076PMC
April 2017

International Survey of Critically Ill Children With Acute Neurologic Insults: The Prevalence of Acute Critical Neurological Disease in Children: A Global Epidemiological Assessment Study.

Pediatr Crit Care Med 2017 Apr;18(4):330-342

1Division of Pediatric Critical Care Medicine, Children's Hospital of Pittsburgh, Pittsburgh, PA. 2Department of Critical Care Medicine, Safar Center for Resuscitation Research, Pittsburgh, PA. 3Department of Epidemiology, University of Pittsburgh School of Medicine, Pittsburgh, PA. 4Department of Critical Care Medicine, Clinical Research, Investigation, and Systems Modeling of Acute Illness (CRISMA) Center, Pittsburgh, PA. 5Departments of Neurology and Anaesthesia (Pediatrics), Harvard Medical School and Boston Children's Hospital, Boston, MA. 6Division of Pediatric Intensive Care, Starship Children's Hospital, Auckland, New Zealand. 7Departments of Critical Care and Paediatrics, Hospital for Sick Children, Toronto, ON, Canada. 8Injury Prevention and Research Center and Harborview Medical Center at the University of Washington, Seattle, WA. 9Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA. 10Department of Pediatrics, University of Washington School of Medicine, Seattle, WA. 11Center for Child Health, Behavior, and Development, Seattle Children's Research Institute, Seattle, WA.

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http://dx.doi.org/10.1097/PCC.0000000000001093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380574PMC
April 2017

The far-reaching scope of neuroinflammation after traumatic brain injury.

Nat Rev Neurol 2017 03 10;13(3):171-191. Epub 2017 Feb 10.

Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, 3434 Fifth Avenue, Pittsburgh, Pennsylvania 15260, USA.

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http://dx.doi.org/10.1038/nrneurol.2017.13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675525PMC
March 2017

Probenecid and N-Acetylcysteine Prevent Loss of Intracellular Glutathione and Inhibit Neuronal Death after Mechanical Stretch Injury In Vitro.

J Neurotrauma 2016 10 22;33(20):1913-1917. Epub 2016 Mar 22.

1 Department of Critical Care Medicine, University of Pittsburgh School of Medicine , Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1089/neu.2015.4342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079409PMC
October 2016

Plasma Mitochondrial DNA--a Novel DAMP in Pediatric Sepsis.

Shock 2016 May;45(5):506-11

*Department of Critical Care Medicine, University of Pittsburgh School of Medicine and Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania †University at Buffalo, State University of New York at Buffalo, Buffalo, New York ‡Department of Chemistry, Carnegie Mellon University §Departments of Critical Care Medicine and Pediatrics, University of Pittsburgh School of Medicine and Children's Hospital of Pittsburgh, Pittsburgh ||Department of Pediatrics, Division of Pediatric Critical Care Medicine, Penn State Hershey Children's Hospital, Pennsylvania State University College of Medicine, Hershey, Pennsylvania.

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http://pdfs.journals.lww.com/shockjournal/9000/00000/Plasma_
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
Publisher Site
http://dx.doi.org/10.1097/SHK.0000000000000539DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322958PMC
May 2016

Intracranial Hypertension and Cerebral Hypoperfusion in Children With Severe Traumatic Brain Injury: Thresholds and Burden in Accidental and Abusive Insults.

Pediatr Crit Care Med 2016 05;17(5):444-50

1Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA. 2Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, Pittsburgh, PA. 3Department of Epidemiology and Biostatistics, University of Pittsburgh School of Medicine, Pittsburgh, PA. 4Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA. 5Barrow Neurological Institute at Phoenix Children's Hospital, Department of Neurological Surgery, Phoenix, AZ.

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http://dx.doi.org/10.1097/PCC.0000000000000709DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856573PMC
May 2016

Effectiveness of Pharmacological Therapies for Intracranial Hypertension in Children With Severe Traumatic Brain Injury--Results From an Automated Data Collection System Time-Synched to Drug Administration.

Pediatr Crit Care Med 2016 Mar;17(3):236-45

1Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA. 2Safar Center for Resuscitation Research, University of Pittsburgh, Pittsburgh, PA. 3Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA. 4Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA.

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http://dx.doi.org/10.1097/PCC.0000000000000610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779724PMC
March 2016

Expression of ATP-Binding Cassette Transporters B1 and C1 after Severe Traumatic Brain Injury in Humans.

J Neurotrauma 2016 Jan 17;33(2):226-31. Epub 2015 Jun 17.

1 Department of Critical Care Medicine, University of Pittsburgh School of Medicine , the Safar Center for Resuscitation Research and the Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1089/neu.2015.3879DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722575PMC
January 2016

Traumatic brain injury research highlights in 2015.

Lancet Neurol 2016 Jan 8;15(1):13-5. Epub 2015 Dec 8.

Safar Center for Resuscitation Research, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260 USA.

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http://dx.doi.org/10.1016/S1474-4422(15)00339-7DOI Listing
January 2016

Under Pressure: Defining Management Goals for Pediatric Traumatic Brain Injury.

Pediatr Crit Care Med 2015 Oct;16(8):777-8

University of Pittsburgh School of Medicine, Pittsburgh, PA Departments of Critical Care Medicine and Pediatrics, Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh School of Medicine, The Safar Center for Resuscitation Research, University of Pittsburgh, Pittsburgh, PA.

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http://dx.doi.org/10.1097/PCC.0000000000000501DOI Listing
October 2015

Evaluation of Electronic Medical Record Vital Sign Data Versus a Commercially Available Acuity Score in Predicting Need for Critical Intervention at a Tertiary Children's Hospital.

Pediatr Crit Care Med 2015 Sep;16(7):644-51

1Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA. 2Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA. 3Clinical and Translational Science Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA. 4Safar Center for Resuscitation Research, Pittsburgh, PA. 5Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA.

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http://dx.doi.org/10.1097/PCC.0000000000000444DOI Listing
September 2015

Ischemia-induced autophagy contributes to neurodegeneration in cerebellar Purkinje cells in the developing rat brain and in primary cortical neurons in vitro.

Biochim Biophys Acta 2015 Sep 11;1852(9):1902-11. Epub 2015 Jun 11.

Department of Critical Care Medicine, The Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Department of Pediatrics, University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, USA; Clinical and Translational Science Institute, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09254439150017
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http://dx.doi.org/10.1016/j.bbadis.2015.06.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523442PMC
September 2015

Cerebrospinal Fluid Markers of Macrophage and Lymphocyte Activation After Traumatic Brain Injury in Children.

Pediatr Crit Care Med 2015 Jul;16(6):549-57

1Department of Pediatrics, University of Iowa, Iowa City, IA. 2Department of Pediatrics, University of California San Diego, La Jolla, CA. 3Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA. 4Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA. 5The Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA. 6Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, Pittsburgh, PA. 7Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA. 8Department of Anesthesiology, University of Pittsburgh School of Medicine, Pittsburgh, PA. 9Department of Environmental and Occupational Health, University of Pittsburgh School of Medicine, Pittsburgh, PA. 10Clinical and Translational Science Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA.

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http://dx.doi.org/10.1097/PCC.0000000000000400DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497935PMC
July 2015

Poly(ADP-ribose) polymerase 1-sirtuin 1 functional interplay regulates LPS-mediated high mobility group box 1 secretion.

Mol Med 2015 Mar 12;20:612-24. Epub 2015 Mar 12.

Departments of Critical Care Medicine and Pediatrics, University of Pittsburgh School of Medicine and Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.

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http://dx.doi.org/10.2119/molmed.2014.00156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365057PMC
March 2015

The nuclear splicing factor RNA binding motif 5 promotes caspase activation in human neuronal cells, and increases after traumatic brain injury in mice.

J Cereb Blood Flow Metab 2015 Mar 31;35(4):655-66. Epub 2015 Mar 31.

Department of Critical Care Medicine, Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1038/jcbfm.2014.242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420885PMC
March 2015

Blood brain barrier is impermeable to solutes and permeable to water after experimental pediatric cardiac arrest.

Neurosci Lett 2014 Aug 14;578:17-21. Epub 2014 Jun 14.

University of Pittsburgh, Department of Pediatrics, 4401 Penn Avenue, Pittsburgh, PA 15224, USA; University of Pittsburgh, Safar Center for Resuscitation Research, 3434 Fifth Avenue, Pittsburgh, PA 15260, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neulet.2014.06.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246011PMC
August 2014

Cerebrospinal fluid mitochondrial DNA: a novel DAMP in pediatric traumatic brain injury.

Shock 2014 Jun;41(6):499-503

*Department of Critical Care Medicine, †University at Buffalo, State University of New York, Buffalo, New York; ‡Department of Chemistry, Carnegie Mellon University; and §Departments of Critical Care Medicine and Pediatrics, and ∥Critical Care Medicine and Neurosurgery, University of Pittsburgh School of Medicine and Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1097/SHK.0000000000000160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4024373PMC
June 2014

Serum biomarkers of brain injury to classify outcome after pediatric cardiac arrest*.

Crit Care Med 2014 Mar;42(3):664-74

1Department of Critical Care Medicine, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA. 2Department of Pediatrics, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA. 3Department of Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA. 4Statistical Analysis and Measurement Consultants, Inc., Lanexa, VA. 5Department of Radiology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA. 6Department of Emergency Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA.

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http://dx.doi.org/10.1097/01.ccm.0000435668.53188.80DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478619PMC
March 2014

No pain, no gain in pediatric sepsis?*.

Pediatr Crit Care Med 2014 Mar;15(3):264-6

Department of Critical Care Medicine; and Department of Pediatrics University of Pittsburgh School of Medicine Children's Hospital of Pittsburgh of UPMC Pittsburgh, PA.

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http://dx.doi.org/10.1097/PCC.0000000000000089DOI Listing
March 2014

Brain tissue oxygen monitoring identifies cortical hypoxia and thalamic hyperoxia after experimental cardiac arrest in rats.

Pediatr Res 2014 Feb 13;75(2):295-301. Epub 2013 Nov 13.

1] Safar Center for Resuscitation Research, University of Pittsburgh, Pittsburgh, Pennsylvania [2] Department of Pediatrics, University of Pittsburgh, Pittsburgh, Pennsylvania [3] Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1038/pr.2013.220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970819PMC
February 2014

Influence of ATP-binding cassette polymorphisms on neurological outcome after traumatic brain injury.

Neurocrit Care 2013 Oct;19(2):192-8

Department of Emergency Medicine, University of Cincinnati, 231 Albert Sabin Way, PO Box 670769, Cincinnati, OH, 45267-0769, USA,

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332629PMC
October 2013

The potential for bio-mediators and biomarkers in pediatric traumatic brain injury and neurocritical care.

Front Neurol 2013 26;4:40. Epub 2013 Apr 26.

Safar Center for Resuscitation Research, Department of Critical Care Medicine, University of Pittsburgh School of Medicine Pittsburgh, PA, USA.

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http://dx.doi.org/10.3389/fneur.2013.00040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636482PMC
May 2013

Acute encephalitis.

Crit Care Clin 2013 Apr 11;29(2):259-77. Epub 2013 Feb 11.

Department of Critical Care Medicine, The Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh School of Medicine, 4401 Penn Avenue, Pittsburgh, PA 15224, USA.

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April 2013

Cerebrospinal fluid levels of high-mobility group box 1 and cytochrome C predict outcome after pediatric traumatic brain injury.

J Neurotrauma 2012 Jul 27;29(11):2013-21. Epub 2012 Apr 27.

Department of Critical Care Medicine, Safar Center for Resuscitation Research and the Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1089/neu.2011.2171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408241PMC
July 2012

Thalamocortical dysfunction and thalamic injury after asphyxial cardiac arrest in developing rats.

J Neurosci 2012 Apr;32(14):4972-81

Department of Critical Care, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.5597-11.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350787PMC
April 2012

Guidelines for the use and interpretation of assays for monitoring autophagy.

Authors:
Daniel J Klionsky Fabio C Abdalla Hagai Abeliovich Robert T Abraham Abraham Acevedo-Arozena Khosrow Adeli Lotta Agholme Maria Agnello Patrizia Agostinis Julio A Aguirre-Ghiso Hyung Jun Ahn Ouardia Ait-Mohamed Slimane Ait-Si-Ali Takahiko Akematsu Shizuo Akira Hesham M Al-Younes Munir A Al-Zeer Matthew L Albert Roger L Albin Javier Alegre-Abarrategui Maria Francesca Aleo Mehrdad Alirezaei Alexandru Almasan Maylin Almonte-Becerril Atsuo Amano Ravi Amaravadi Shoba Amarnath Amal O Amer Nathalie Andrieu-Abadie Vellareddy Anantharam David K Ann Shailendra Anoopkumar-Dukie Hiroshi Aoki Nadezda Apostolova Giuseppe Arancia John P Aris Katsuhiko Asanuma Nana Y O Asare Hisashi Ashida Valerie Askanas David S Askew Patrick Auberger Misuzu Baba Steven K Backues Eric H Baehrecke Ben A Bahr Xue-Yuan Bai Yannick Bailly Robert Baiocchi Giulia Baldini Walter Balduini Andrea Ballabio Bruce A Bamber Edward T W Bampton Gábor Bánhegyi Clinton R Bartholomew Diane C Bassham Robert C Bast Henri Batoko Boon-Huat Bay Isabelle Beau Daniel M Béchet Thomas J Begley Christian Behl Christian Behrends Soumeya Bekri Bryan Bellaire Linda J Bendall Luca Benetti Laura Berliocchi Henri Bernardi Francesca Bernassola Sébastien Besteiro Ingrid Bhatia-Kissova Xiaoning Bi Martine Biard-Piechaczyk Janice S Blum Lawrence H Boise Paolo Bonaldo David L Boone Beat C Bornhauser Karina R Bortoluci Ioannis Bossis Frédéric Bost Jean-Pierre Bourquin Patricia Boya Michaël Boyer-Guittaut Peter V Bozhkov Nathan R Brady Claudio Brancolini Andreas Brech Jay E Brenman Ana Brennand Emery H Bresnick Patrick Brest Dave Bridges Molly L Bristol Paul S Brookes Eric J Brown John H Brumell Nicola Brunetti-Pierri Ulf T Brunk Dennis E Bulman Scott J Bultman Geert Bultynck Lena F Burbulla Wilfried Bursch Jonathan P Butchar Wanda Buzgariu Sergio P Bydlowski Ken Cadwell Monika Cahová Dongsheng Cai Jiyang Cai Qian Cai Bruno Calabretta Javier Calvo-Garrido Nadine Camougrand Michelangelo Campanella Jenny Campos-Salinas Eleonora Candi Lizhi Cao Allan B Caplan Simon R Carding Sandra M Cardoso Jennifer S Carew Cathleen R Carlin Virginie Carmignac Leticia A M Carneiro Serena Carra Rosario A Caruso Giorgio Casari Caty Casas Roberta Castino Eduardo Cebollero Francesco Cecconi Jean Celli Hassan Chaachouay Han-Jung Chae Chee-Yin Chai David C Chan Edmond Y Chan Raymond Chuen-Chung Chang Chi-Ming Che Ching-Chow Chen Guang-Chao Chen Guo-Qiang Chen Min Chen Quan Chen Steve S-L Chen WenLi Chen Xi Chen Xiangmei Chen Xiequn Chen Ye-Guang Chen Yingyu Chen Yongqiang Chen Yu-Jen Chen Zhixiang Chen Alan Cheng Christopher H K Cheng Yan Cheng Heesun Cheong Jae-Ho Cheong Sara Cherry Russ Chess-Williams Zelda H Cheung Eric Chevet Hui-Ling Chiang Roberto Chiarelli Tomoki Chiba Lih-Shen Chin Shih-Hwa Chiou Francis V Chisari Chi Hin Cho Dong-Hyung Cho Augustine M K Choi DooSeok Choi Kyeong Sook Choi Mary E Choi Salem Chouaib Divaker Choubey Vinay Choubey Charleen T Chu Tsung-Hsien Chuang Sheau-Huei Chueh Taehoon Chun Yong-Joon Chwae Mee-Len Chye Roberto Ciarcia Maria R Ciriolo Michael J Clague Robert S B Clark Peter G H Clarke Robert Clarke Patrice Codogno Hilary A Coller María I Colombo Sergio Comincini Maria Condello Fabrizio Condorelli Mark R Cookson Graham H Coombs Isabelle Coppens Ramon Corbalan Pascale Cossart Paola Costelli Safia Costes Ana Coto-Montes Eduardo Couve Fraser P Coxon James M Cregg José L Crespo Marianne J Cronjé Ana Maria Cuervo Joseph J Cullen Mark J Czaja Marcello D'Amelio Arlette Darfeuille-Michaud Lester M Davids Faith E Davies Massimo De Felici John F de Groot Cornelis A M de Haan Luisa De Martino Angelo De Milito Vincenzo De Tata Jayanta Debnath Alexei Degterev Benjamin Dehay Lea M D Delbridge Francesca Demarchi Yi Zhen Deng Jörn Dengjel Paul Dent Donna Denton Vojo Deretic Shyamal D Desai Rodney J Devenish Mario Di Gioacchino Gilbert Di Paolo Chiara Di Pietro Guillermo Díaz-Araya Inés Díaz-Laviada Maria T Diaz-Meco Javier Diaz-Nido Ivan Dikic Savithramma P Dinesh-Kumar Wen-Xing Ding Clark W Distelhorst Abhinav Diwan Mojgan Djavaheri-Mergny Svetlana Dokudovskaya Zheng Dong Frank C Dorsey Victor Dosenko James J Dowling Stephen Doxsey Marlène Dreux Mark E Drew Qiuhong Duan Michel A Duchosal Karen Duff Isabelle Dugail Madeleine Durbeej Michael Duszenko Charles L Edelstein Aimee L Edinger Gustavo Egea Ludwig Eichinger N Tony Eissa Suhendan Ekmekcioglu Wafik S El-Deiry Zvulun Elazar Mohamed Elgendy Lisa M Ellerby Kai Er Eng Anna-Mart Engelbrecht Simone Engelender Jekaterina Erenpreisa Ricardo Escalante Audrey Esclatine Eeva-Liisa Eskelinen Lucile Espert Virginia Espina Huizhou Fan Jia Fan Qi-Wen Fan Zhen Fan Shengyun Fang Yongqi Fang Manolis Fanto Alessandro Fanzani Thomas Farkas Jean-Claude Farré Mathias Faure Marcus Fechheimer Carl G Feng Jian Feng Qili Feng Youji Feng László Fésüs Ralph Feuer Maria E Figueiredo-Pereira Gian Maria Fimia Diane C Fingar Steven Finkbeiner Toren Finkel Kim D Finley Filomena Fiorito Edward A Fisher Paul B Fisher Marc Flajolet Maria L Florez-McClure Salvatore Florio Edward A Fon Francesco Fornai Franco Fortunato Rati Fotedar Daniel H Fowler Howard S Fox Rodrigo Franco Lisa B Frankel Marc Fransen José M Fuentes Juan Fueyo Jun Fujii Kozo Fujisaki Eriko Fujita Mitsunori Fukuda Ruth H Furukawa Matthias Gaestel Philippe Gailly Malgorzata Gajewska Brigitte Galliot Vincent Galy Subramaniam Ganesh Barry Ganetzky Ian G Ganley Fen-Biao Gao George F Gao Jinming Gao Lorena Garcia Guillermo Garcia-Manero Mikel Garcia-Marcos Marjan Garmyn Andrei L Gartel Evelina Gatti Mathias Gautel Thomas R Gawriluk Matthew E Gegg Jiefei Geng Marc Germain Jason E Gestwicki David A Gewirtz Saeid Ghavami Pradipta Ghosh Anna M Giammarioli Alexandra N Giatromanolaki Spencer B Gibson Robert W Gilkerson Michael L Ginger Henry N Ginsberg Jakub Golab Michael S Goligorsky Pierre Golstein Candelaria Gomez-Manzano Ebru Goncu Céline Gongora Claudio D Gonzalez Ramon Gonzalez Cristina González-Estévez Rosa Ana González-Polo Elena Gonzalez-Rey Nikolai V Gorbunov Sharon Gorski Sandro Goruppi Roberta A Gottlieb Devrim Gozuacik Giovanna Elvira Granato Gary D Grant Kim N Green Aleš Gregorc Frédéric Gros Charles Grose Thomas W Grunt Philippe Gual Jun-Lin Guan Kun-Liang Guan Sylvie M Guichard Anna S Gukovskaya Ilya Gukovsky Jan Gunst Asa B Gustafsson Andrew J Halayko Amber N Hale Sandra K Halonen Maho Hamasaki Feng Han Ting Han Michael K Hancock Malene Hansen Hisashi Harada Masaru Harada Stefan E Hardt J Wade Harper Adrian L Harris James Harris Steven D Harris Makoto Hashimoto Jeffrey A Haspel Shin-ichiro Hayashi Lori A Hazelhurst Congcong He You-Wen He Marie-Joseé Hébert Kim A Heidenreich Miep H Helfrich Gudmundur V Helgason Elizabeth P Henske Brian Herman Paul K Herman Claudio Hetz Sabine Hilfiker Joseph A Hill Lynne J Hocking Paul Hofman Thomas G Hofmann Jörg Höhfeld Tessa L Holyoake Ming-Huang Hong David A Hood Gökhan S Hotamisligil Ewout J Houwerzijl Maria Høyer-Hansen Bingren Hu Chien-An A Hu Hong-Ming Hu Ya Hua Canhua Huang Ju Huang Shengbing Huang Wei-Pang Huang Tobias B Huber Won-Ki Huh Tai-Ho Hung Ted R Hupp Gang Min Hur James B Hurley Sabah N A Hussain Patrick J Hussey Jung Jin Hwang Seungmin Hwang Atsuhiro Ichihara Shirin Ilkhanizadeh Ken Inoki Takeshi Into Valentina Iovane Juan L Iovanna Nancy Y Ip Yoshitaka Isaka Hiroyuki Ishida Ciro Isidoro Ken-ichi Isobe Akiko Iwasaki Marta Izquierdo Yotaro Izumi Panu M Jaakkola Marja Jäättelä George R Jackson William T Jackson Bassam Janji Marina Jendrach Ju-Hong Jeon Eui-Bae Jeung Hong Jiang Hongchi Jiang Jean X Jiang Ming Jiang Qing Jiang Xuejun Jiang Xuejun Jiang Alberto Jiménez Meiyan Jin Shengkan Jin Cheol O Joe Terje Johansen Daniel E Johnson Gail V W Johnson Nicola L Jones Bertrand Joseph Suresh K Joseph Annie M Joubert Gábor Juhász Lucienne Juillerat-Jeanneret Chang Hwa Jung Yong-Keun Jung Kai Kaarniranta Allen Kaasik Tomohiro Kabuta Motoni Kadowaki Katarina Kagedal Yoshiaki Kamada Vitaliy O Kaminskyy Harm H Kampinga Hiromitsu Kanamori Chanhee Kang Khong Bee Kang Kwang Il Kang Rui Kang Yoon-A Kang Tomotake Kanki Thirumala-Devi Kanneganti Haruo Kanno Anumantha G Kanthasamy Arthi Kanthasamy Vassiliki Karantza Gur P Kaushal Susmita Kaushik Yoshinori Kawazoe Po-Yuan Ke John H Kehrl Ameeta Kelekar Claus Kerkhoff David H Kessel Hany Khalil Jan A K W Kiel Amy A Kiger Akio Kihara Deok Ryong Kim Do-Hyung Kim Dong-Hou Kim Eun-Kyoung Kim Hyung-Ryong Kim Jae-Sung Kim Jeong Hun Kim Jin Cheon Kim John K Kim Peter K Kim Seong Who Kim Yong-Sun Kim Yonghyun Kim Adi Kimchi Alec C Kimmelman Jason S King Timothy J Kinsella Vladimir Kirkin Lorrie A Kirshenbaum Katsuhiko Kitamoto Kaio Kitazato Ludger Klein Walter T Klimecki Jochen Klucken Erwin Knecht Ben C B Ko Jan C Koch Hiroshi Koga Jae-Young Koh Young Ho Koh Masato Koike Masaaki Komatsu Eiki Kominami Hee Jeong Kong Wei-Jia Kong Viktor I Korolchuk Yaichiro Kotake Michael I Koukourakis Juan B Kouri Flores Attila L Kovács Claudine Kraft Dimitri Krainc Helmut Krämer Carole Kretz-Remy Anna M Krichevsky Guido Kroemer Rejko Krüger Oleg Krut Nicholas T Ktistakis Chia-Yi Kuan Roza Kucharczyk Ashok Kumar Raj Kumar Sharad Kumar Mondira Kundu Hsing-Jien Kung Tino Kurz Ho Jeong Kwon Albert R La Spada Frank Lafont Trond Lamark Jacques Landry Jon D Lane Pierre Lapaquette Jocelyn F Laporte Lajos László Sergio Lavandero Josée N Lavoie Robert Layfield Pedro A Lazo Weidong Le Laurent Le Cam Daniel J Ledbetter Alvin J X Lee Byung-Wan Lee Gyun Min Lee Jongdae Lee Ju-Hyun Lee Michael Lee Myung-Shik Lee Sug Hyung Lee Christiaan Leeuwenburgh Patrick Legembre Renaud Legouis Michael Lehmann Huan-Yao Lei Qun-Ying Lei David A Leib José Leiro John J Lemasters Antoinette Lemoine Maciej S Lesniak Dina Lev Victor V Levenson Beth Levine Efrat Levy Faqiang Li Jun-Lin Li Lian Li Sheng Li Weijie Li Xue-Jun Li Yan-bo Li Yi-Ping Li Chengyu Liang Qiangrong Liang Yung-Feng Liao Pawel P Liberski Andrew Lieberman Hyunjung J Lim Kah-Leong Lim Kyu Lim Chiou-Feng Lin Fu-Cheng Lin Jian Lin Jiandie D Lin Kui Lin Wan-Wan Lin Weei-Chin Lin Yi-Ling Lin Rafael Linden Paul Lingor Jennifer Lippincott-Schwartz Michael P Lisanti Paloma B Liton Bo Liu Chun-Feng Liu Kaiyu Liu Leyuan Liu Qiong A Liu Wei Liu Young-Chau Liu Yule Liu Richard A Lockshin Chun-Nam Lok Sagar Lonial Benjamin Loos Gabriel Lopez-Berestein Carlos López-Otín Laura Lossi Michael T Lotze Peter Lőw Binfeng Lu Bingwei Lu Bo Lu Zhen Lu Frédéric Luciano Nicholas W Lukacs Anders H Lund Melinda A Lynch-Day Yong Ma Fernando Macian Jeff P MacKeigan Kay F Macleod Frank Madeo Luigi Maiuri Maria Chiara Maiuri Davide Malagoli May Christine V Malicdan Walter Malorni Na Man Eva-Maria Mandelkow Stéphen Manon Irena Manov Kai Mao Xiang Mao Zixu Mao Philippe Marambaud Daniela Marazziti Yves L Marcel Katie Marchbank Piero Marchetti Stefan J Marciniak Mateus Marcondes Mohsen Mardi Gabriella Marfe Guillermo Mariño Maria Markaki Mark R Marten Seamus J Martin Camille Martinand-Mari Wim Martinet Marta Martinez-Vicente Matilde Masini Paola Matarrese Saburo Matsuo Raffaele Matteoni Andreas Mayer Nathalie M Mazure David J McConkey Melanie J McConnell Catherine McDermott Christine McDonald Gerald M McInerney Sharon L McKenna BethAnn McLaughlin Pamela J McLean Christopher R McMaster G Angus McQuibban Alfred J Meijer Miriam H Meisler Alicia Meléndez Thomas J Melia Gerry Melino Maria A Mena Javier A Menendez Rubem F S Menna-Barreto Manoj B Menon Fiona M Menzies Carol A Mercer Adalberto Merighi Diane E Merry Stefania Meschini Christian G Meyer Thomas F Meyer Chao-Yu Miao Jun-Ying Miao Paul A M Michels Carine Michiels Dalibor Mijaljica Ana Milojkovic Saverio Minucci Clelia Miracco Cindy K Miranti Ioannis Mitroulis Keisuke Miyazawa Noboru Mizushima Baharia Mograbi Simin Mohseni Xavier Molero Bertrand Mollereau Faustino Mollinedo Takashi Momoi Iryna Monastyrska Martha M Monick Mervyn J Monteiro Michael N Moore Rodrigo Mora Kevin Moreau Paula I Moreira Yuji Moriyasu Jorge Moscat Serge Mostowy Jeremy C Mottram Tomasz Motyl Charbel E-H Moussa Sylke Müller Sylviane Muller Karl Münger Christian Münz Leon O Murphy Maureen E Murphy Antonio Musarò Indira Mysorekar Eiichiro Nagata Kazuhiro Nagata Aimable Nahimana Usha Nair Toshiyuki Nakagawa Kiichi Nakahira Hiroyasu Nakano Hitoshi Nakatogawa Meera Nanjundan Naweed I Naqvi Derek P Narendra Masashi Narita Miguel Navarro Steffan T Nawrocki Taras Y Nazarko Andriy Nemchenko Mihai G Netea Thomas P Neufeld Paul A Ney Ioannis P Nezis Huu Phuc Nguyen Daotai Nie Ichizo Nishino Corey Nislow Ralph A Nixon Takeshi Noda Angelika A Noegel Anna Nogalska Satoru Noguchi Lucia Notterpek Ivana Novak Tomoyoshi Nozaki Nobuyuki Nukina Thorsten Nürnberger Beat Nyfeler Keisuke Obara Terry D Oberley Salvatore Oddo Michinaga Ogawa Toya Ohashi Koji Okamoto Nancy L Oleinick F Javier Oliver Laura J Olsen Stefan Olsson Onya Opota Timothy F Osborne Gary K Ostrander Kinya Otsu Jing-hsiung James Ou Mireille Ouimet Michael Overholtzer Bulent Ozpolat Paolo Paganetti Ugo Pagnini Nicolas Pallet Glen E Palmer Camilla Palumbo Tianhong Pan Theocharis Panaretakis Udai Bhan Pandey Zuzana Papackova Issidora Papassideri Irmgard Paris Junsoo Park Ohkmae K Park Jan B Parys Katherine R Parzych Susann Patschan Cam Patterson Sophie Pattingre John M Pawelek Jianxin Peng David H Perlmutter Ida Perrotta George Perry Shazib Pervaiz Matthias Peter Godefridus J Peters Morten Petersen Goran Petrovski James M Phang Mauro Piacentini Philippe Pierre Valérie Pierrefite-Carle Gérard Pierron Ronit Pinkas-Kramarski Antonio Piras Natik Piri Leonidas C Platanias Stefanie Pöggeler Marc Poirot Angelo Poletti Christian Poüs Mercedes Pozuelo-Rubio Mette Prætorius-Ibba Anil Prasad Mark Prescott Muriel Priault Nathalie Produit-Zengaffinen Ann Progulske-Fox Tassula Proikas-Cezanne Serge Przedborski Karin Przyklenk Rosa Puertollano Julien Puyal Shu-Bing Qian Liang Qin Zheng-Hong Qin Susan E Quaggin Nina Raben Hannah Rabinowich Simon W Rabkin Irfan Rahman Abdelhaq Rami Georg Ramm Glenn Randall Felix Randow V Ashutosh Rao Jeffrey C Rathmell Brinda Ravikumar Swapan K Ray Bruce H Reed John C Reed Fulvio Reggiori Anne Régnier-Vigouroux Andreas S Reichert John J Reiners Russel J Reiter Jun Ren José L Revuelta Christopher J Rhodes Konstantinos Ritis Elizete Rizzo Jeffrey Robbins Michel Roberge Hernan Roca Maria C Roccheri Stephane Rocchi H Peter Rodemann Santiago Rodríguez de Córdoba Bärbel Rohrer Igor B Roninson Kirill Rosen Magdalena M Rost-Roszkowska Mustapha Rouis Kasper M A Rouschop Francesca Rovetta Brian P Rubin David C Rubinsztein Klaus Ruckdeschel Edmund B Rucker Assaf Rudich Emil Rudolf Nelson Ruiz-Opazo Rossella Russo Tor Erik Rusten Kevin M Ryan Stefan W Ryter David M Sabatini Junichi Sadoshima Tapas Saha Tatsuya Saitoh Hiroshi Sakagami Yasuyoshi Sakai Ghasem Hoseini Salekdeh Paolo Salomoni Paul M Salvaterra Guy Salvesen Rosa Salvioli Anthony M J Sanchez José A Sánchez-Alcázar Ricardo Sánchez-Prieto Marco Sandri Uma Sankar Poonam Sansanwal Laura Santambrogio Shweta Saran Sovan Sarkar Minnie Sarwal Chihiro Sasakawa Ausra Sasnauskiene Miklós Sass Ken Sato Miyuki Sato Anthony H V Schapira Michael Scharl Hermann M Schätzl Wiep Scheper Stefano Schiaffino Claudio Schneider Marion E Schneider Regine Schneider-Stock Patricia V Schoenlein Daniel F Schorderet Christoph Schüller Gary K Schwartz Luca Scorrano Linda Sealy Per O Seglen Juan Segura-Aguilar Iban Seiliez Oleksandr Seleverstov Christian Sell Jong Bok Seo Duska Separovic Vijayasaradhi Setaluri Takao Setoguchi Carmine Settembre John J Shacka Mala Shanmugam Irving M Shapiro Eitan Shaulian Reuben J Shaw James H Shelhamer Han-Ming Shen Wei-Chiang Shen Zu-Hang Sheng Yang Shi Kenichi Shibuya Yoshihiro Shidoji Jeng-Jer Shieh Chwen-Ming Shih Yohta Shimada Shigeomi Shimizu Takahiro Shintani Orian S Shirihai Gordon C Shore Andriy A Sibirny Stan B Sidhu Beata Sikorska Elaine C M Silva-Zacarin Alison Simmons Anna Katharina Simon Hans-Uwe Simon Cristiano Simone Anne Simonsen David A Sinclair Rajat Singh Debasish Sinha Frank A Sinicrope Agnieszka Sirko Parco M Siu Efthimios Sivridis Vojtech Skop Vladimir P Skulachev Ruth S Slack Soraya S Smaili Duncan R Smith Maria S Soengas Thierry Soldati Xueqin Song Anil K Sood Tuck Wah Soong Federica Sotgia Stephen A Spector Claudia D Spies Wolfdieter Springer Srinivasa M Srinivasula Leonidas Stefanis Joan S Steffan Ruediger Stendel Harald Stenmark Anastasis Stephanou Stephan T Stern Cinthya Sternberg Björn Stork Peter Strålfors Carlos S Subauste Xinbing Sui David Sulzer Jiaren Sun Shi-Yong Sun Zhi-Jun Sun Joseph J Y Sung Kuninori Suzuki Toshihiko Suzuki Michele S Swanson Charles Swanton Sean T Sweeney Lai-King Sy Gyorgy Szabadkai Ira Tabas Heinrich Taegtmeyer Marco Tafani Krisztina Takács-Vellai Yoshitaka Takano Kaoru Takegawa Genzou Takemura Fumihiko Takeshita Nicholas J Talbot Kevin S W Tan Keiji Tanaka Kozo Tanaka Daolin Tang Dingzhong Tang Isei Tanida Bakhos A Tannous Nektarios Tavernarakis Graham S Taylor Gregory A Taylor J Paul Taylor Lance S Terada Alexei Terman Gianluca Tettamanti Karin Thevissen Craig B Thompson Andrew Thorburn Michael Thumm FengFeng Tian Yuan Tian Glauco Tocchini-Valentini Aviva M Tolkovsky Yasuhiko Tomino Lars Tönges Sharon A Tooze Cathy Tournier John Tower Roberto Towns Vladimir Trajkovic Leonardo H Travassos Ting-Fen Tsai Mario P Tschan Takeshi Tsubata Allan Tsung Boris Turk Lorianne S Turner Suresh C Tyagi Yasuo Uchiyama Takashi Ueno Midori Umekawa Rika Umemiya-Shirafuji Vivek K Unni Maria I Vaccaro Enza Maria Valente Greet Van den Berghe Ida J van der Klei Wouter van Doorn Linda F van Dyk Marjolein van Egmond Leo A van Grunsven Peter Vandenabeele Wim P Vandenberghe Ilse Vanhorebeek Eva C Vaquero Guillermo Velasco Tibor Vellai Jose Miguel Vicencio Richard D Vierstra Miquel Vila Cécile Vindis Giampietro Viola Maria Teresa Viscomi Olga V Voitsekhovskaja Clarissa von Haefen Marcela Votruba Keiji Wada Richard Wade-Martins Cheryl L Walker Craig M Walsh Jochen Walter Xiang-Bo Wan Aimin Wang Chenguang Wang Dawei Wang Fan Wang Fen Wang Guanghui Wang Haichao Wang Hong-Gang Wang Horng-Dar Wang Jin Wang Ke Wang Mei Wang Richard C Wang Xinglong Wang Xuejun Wang Ying-Jan Wang Yipeng Wang Zhen Wang Zhigang Charles Wang Zhinong Wang Derick G Wansink Diane M Ward Hirotaka Watada Sarah L Waters Paul Webster Lixin Wei Conrad C Weihl William A Weiss Scott M Welford Long-Ping Wen Caroline A Whitehouse J Lindsay Whitton Alexander J Whitworth Tom Wileman John W Wiley Simon Wilkinson Dieter Willbold Roger L Williams Peter R Williamson Bradly G Wouters Chenghan Wu Dao-Cheng Wu William K K Wu Andreas Wyttenbach Ramnik J Xavier Zhijun Xi Pu Xia Gengfu Xiao Zhiping Xie Zhonglin Xie Da-zhi Xu Jianzhen Xu Liang Xu Xiaolei Xu Ai Yamamoto Akitsugu Yamamoto Shunhei Yamashina Michiaki Yamashita Xianghua Yan Mitsuhiro Yanagida Dun-Sheng Yang Elizabeth Yang Jin-Ming Yang Shi Yu Yang Wannian Yang Wei Yuan Yang Zhifen Yang Meng-Chao Yao Tso-Pang Yao Behzad Yeganeh Wei-Lien Yen Jia-jing Yin Xiao-Ming Yin Ook-Joon Yoo Gyesoon Yoon Seung-Yong Yoon Tomohiro Yorimitsu Yuko Yoshikawa Tamotsu Yoshimori Kohki Yoshimoto Ho Jin You Richard J Youle Anas Younes Li Yu Long Yu Seong-Woon Yu Wai Haung Yu Zhi-Min Yuan Zhenyu Yue Cheol-Heui Yun Michisuke Yuzaki Olga Zabirnyk Elaine Silva-Zacarin David Zacks Eldad Zacksenhaus Nadia Zaffaroni Zahra Zakeri Herbert J Zeh Scott O Zeitlin Hong Zhang Hui-Ling Zhang Jianhua Zhang Jing-Pu Zhang Lin Zhang Long Zhang Ming-Yong Zhang Xu Dong Zhang Mantong Zhao Yi-Fang Zhao Ying Zhao Zhizhuang J Zhao Xiaoxiang Zheng Boris Zhivotovsky Qing Zhong Cong-Zhao Zhou Changlian Zhu Wei-Guo Zhu Xiao-Feng Zhu Xiongwei Zhu Yuangang Zhu Teresa Zoladek Wei-Xing Zong Antonio Zorzano Jürgen Zschocke Brian Zuckerbraun

Autophagy 2012 Apr;8(4):445-544

Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA.

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April 2012

Fever control and application of hypothermia using intravenous cold saline.

Pediatr Crit Care Med 2012 Jan;13(1):80-4

Department of Critical Care Medicine, Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine and Children's Hospital of Pittsburgh, Pittsburgh, PA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638805PMC
January 2012

Detecting and quantifying pADPr in vivo.

Methods Mol Biol 2011 ;780:117-34

Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.

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January 2012

Unmasking sex-based disparity in neuronal metabolism.

Curr Pharm Des 2011 Dec;17(35):3854-60

Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

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December 2011

Brain injuries and neurological system failure are the most common proximate causes of death in children admitted to a pediatric intensive care unit.

Pediatr Crit Care Med 2011 Sep;12(5):566-71

Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

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September 2011

Brain-systemic temperature gradient is temperature-dependent in children with severe traumatic brain injury.

Pediatr Crit Care Med 2011 Jul;12(4):449-54

Department of Critical Care Medicine, University of Pittsburgh School of Medicine and Children's Hospital of Pittsburgh, Pittsburgh, PA, USA.

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July 2011

Autophagy in acute brain injury: feast, famine, or folly?

Neurobiol Dis 2011 Jul 27;43(1):52-9. Epub 2010 Sep 27.

Department of Critical Care Medicine, Safar Center for Resuscitation Research, Brain Trauma Research Center, and Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15260, USA.

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July 2011

Evaluation of autophagy using mouse models of brain injury.

Biochim Biophys Acta 2010 Oct 30;1802(10):918-23. Epub 2009 Oct 30.

Department of Critical Care Medicine, Safar Center for Resuscitation Research, Brain Trauma Research Center, and Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

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October 2010

How I cool children in neurocritical care.

Neurocrit Care 2010 Jun;12(3):414-20

Department of Critical Care Medicine, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA 15224, USA.

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http://dx.doi.org/10.1007/s12028-010-9334-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221013PMC
June 2010

Influence of PARP-1 polymorphisms in patients after traumatic brain injury.

J Neurotrauma 2010 Mar;27(3):465-71

Safar Center for Resuscitation Research and Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1089/neu.2009.1171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867630PMC
March 2010

Minocycline reduces neuronal death and attenuates microglial response after pediatric asphyxial cardiac arrest.

J Cereb Blood Flow Metab 2010 Jan 16;30(1):119-29. Epub 2009 Sep 16.

Department of Critical Care Medicine, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA.

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http://dx.doi.org/10.1038/jcbfm.2009.194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949095PMC
January 2010

A tertiary care center's experience with therapeutic hypothermia after pediatric cardiac arrest.

Pediatr Crit Care Med 2010 Jan;11(1):66-74

Department of Critical Care Medicine, the Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, and the Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, PA, USA.

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http://dx.doi.org/10.1097/PCC.0b013e3181c58237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654403PMC
January 2010

Postcardiac arrest syndrome: focus on the brain.

Curr Opin Pediatr 2009 Dec;21(6):745-50

Department of Pediatrics, Children's Hospital of Pittsburgh, Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15260, USA.

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http://dx.doi.org/10.1097/MOP.0b013e328331e873DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917225PMC
December 2009