Robert P Mohney

Robert P Mohney

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Robert P Mohney

Robert P Mohney

Publications by authors named "Robert P Mohney"

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Metabolomic profiling identifies novel associations with Electrolyte and Acid-Base Homeostatic patterns.

Sci Rep 2019 Oct 21;9(1):15088. Epub 2019 Oct 21.

Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.

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http://dx.doi.org/10.1038/s41598-019-51492-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803625PMC
October 2019

Characterization of Bulk Phosphatidylcholine Compositions in Human Plasma Using Side-Chain Resolving Lipidomics.

Metabolites 2019 Jun 8;9(6). Epub 2019 Jun 8.

Institute of Bioinformatics and Systems Biology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.

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http://dx.doi.org/10.3390/metabo9060109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631474PMC
June 2019

Metabolomics Identifies Novel Blood Biomarkers of Pulmonary Function and COPD in the General Population.

Metabolites 2019 Apr 1;9(4). Epub 2019 Apr 1.

Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.3390/metabo9040061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523962PMC
April 2019

Circulating levels of the anti-oxidant indoleproprionic acid are associated with higher gut microbiome diversity.

Gut Microbes 2019 29;10(6):688-695. Epub 2019 Apr 29.

Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.

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http://dx.doi.org/10.1080/19490976.2019.1586038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6866703PMC
April 2019

The potential of metabolic profiling for vaccine development.

Semin Immunol 2018 10 19;39:44-51. Epub 2018 Jul 19.

Max Planck Institute for Infection Biology, Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.smim.2018.07.002DOI Listing
October 2018

From Discovery to Translation: Characterization of C-Mannosyltryptophan and Pseudouridine as Markers of Kidney Function.

Sci Rep 2017 12 12;7(1):17400. Epub 2017 Dec 12.

Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center - University of Freiburg, Hugstetter Str. 49, 79106, Freiburg, Germany.

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http://dx.doi.org/10.1038/s41598-017-17107-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727198PMC
December 2017

Serum global metabolomics profiling reveals profound metabolic impairments in patients with MPS IIIA and MPS IIIB.

Metab Brain Dis 2017 10 5;32(5):1403-1415. Epub 2017 Apr 5.

Center for Gene Therapy, The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.

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http://dx.doi.org/10.1007/s11011-017-0009-1DOI Listing
October 2017

Is spaceflight-induced immune dysfunction linked to systemic changes in metabolism?

PLoS One 2017 24;12(5):e0174174. Epub 2017 May 24.

Department of Basic Sciences, Division of Radiation Research, Loma Linda University School of Medicine, Loma Linda, CA, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0174174PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443495PMC
September 2017

Amino acid metabolites that regulate G protein signaling during osmotic stress.

PLoS Genet 2017 May 30;13(5):e1006829. Epub 2017 May 30.

Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1006829DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469498PMC
May 2017

Near-Complete Correction of Profound Metabolomic Impairments Corresponding to Functional Benefit in MPS IIIB Mice after IV rAAV9-hNAGLU Gene Delivery.

Mol Ther 2017 03 28;25(3):792-802. Epub 2017 Jan 28.

Center for Gene Therapy, The Research Institute at Nationwide Children's Hospital (NCH-RI), Columbus, OH 43205, USA; Department of Pediatrics, College of Medicine and Public Health, The Ohio State University, Columbus, OH 43202, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S15250016173000
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http://dx.doi.org/10.1016/j.ymthe.2016.12.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363204PMC
March 2017

Metabolomic profiling to dissect the role of visceral fat in cardiometabolic health.

Obesity (Silver Spring) 2016 06 30;24(6):1380-8. Epub 2016 Apr 30.

Department of Twin Research and Genetic Epidemiology, Kings College London, London, UK.

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http://dx.doi.org/10.1002/oby.21488DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914926PMC
June 2016

Identification of novel biomarkers for Parkinson's disease by metabolomic technologies.

J Neurol Neurosurg Psychiatry 2016 Mar 20;87(3):295-301. Epub 2015 Mar 20.

Department of Neurology, Juntendo University School of Medicine, Tokyo, Japan Core Research for Evolutionary Science and Technology (CREST), Japan Science and Technology Agency, Tokyo, Japan.

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http://jnnp.bmj.com/content/87/3/295.full.pdf
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http://dx.doi.org/10.1136/jnnp-2014-309676DOI Listing
March 2016

Diagnostic and Prognostic Metabolites Identified for Joint Symptoms in the KORA Population.

J Proteome Res 2016 Feb 7;15(2):554-62. Epub 2016 Jan 7.

Department of Medicine, Weill Cornell Medical College - Qatar , Doha 24144, Qatar.

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http://dx.doi.org/10.1021/acs.jproteome.5b00951DOI Listing
February 2016

Food Preference Patterns in a UK Twin Cohort.

Twin Res Hum Genet 2015 Dec 28;18(6):793-805. Epub 2015 Sep 28.

Department of Twin Research and Genetic Epidemiology,King's College London,London,UK.

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http://dx.doi.org/10.1017/thg.2015.69DOI Listing
December 2015

Metabolomics of dates (Phoenix dactylifera) reveals a highly dynamic ripening process accounting for major variation in fruit composition.

BMC Plant Biol 2015 Dec 16;15:291. Epub 2015 Dec 16.

Department of Physiology and Biophysics, Weill Cornell Medical College, Qatar Foundation - Education City, PO Box 24144, Doha, Qatar.

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http://dx.doi.org/10.1186/s12870-015-0672-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681049PMC
December 2015

Metabolomic identification of a novel pathway of blood pressure regulation involving hexadecanedioate.

Hypertension 2015 Aug 1;66(2):422-9. Epub 2015 Jun 1.

From the Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom (C.M., M.M., M.P., T.D.S., A.M.V.); Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom (D.G., N.H.J.A., S.M.A., M.M.B., A.F.D., S.P.); Institute of Bioinformatics and Systems Biology, Helmholtz Zentrum München, Germany (G.K., K.S.); Faculty of Medicine, University of Southampton, Southampton, United Kingdom (P.T., M.H.E., C.C.); Wellcome Trust Sanger Institute Human Genetics, Hinxton, United Kingdom (S.-Y.S., N.S.); MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom (S.-Y.S.); Chemical Analytics, Seibersdorf Labor GmbH, Seibersdorf, Austria (T.G., A.H., C.R.); Institute of Epidemiology II, Helmholtz Zentrum München, Germany (A.P., C.G.); Research Unit Molecular Epidemiology, Helmholtz Zentrum München, Germany (A.P., R.W.-S., T.X.); Cardiovascular and Metabolic Diseases, Pfizer Worldwide Research and Development, Cambridge, MA (M.J.B.); Edison Pharmaceuticals, Mountain View, CA (J.T.); Metabolon, Inc, Durham, NC (R.P.M.); Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom (C.C.); Scottish Pulmonary Vascular Unit, Golden jubilee Hospital, Glasgow, United Kingdom (A.C.C.); Department of Physiology and Biophysics, Weill Cornell Medical College in Qatar, Education City, Qatar Foundation, Doha, Qatar (K.S.); and Academic Rheumatology, University of Nottingham, Nottingham, United Kingdom (A.M.V.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.115.05544DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490909PMC
August 2015

Global metabolomic profiling targeting childhood obesity in the Hispanic population.

Am J Clin Nutr 2015 Aug 17;102(2):256-67. Epub 2015 Jun 17.

Department of Genetics, Texas Biomedical Research Institute, San Antonio, TX.

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http://dx.doi.org/10.3945/ajcn.115.111872DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515872PMC
August 2015

Dipeptide species regulate p38MAPK-Smad3 signalling to maintain chronic myelogenous leukaemia stem cells.

Nat Commun 2015 Aug 20;6:8039. Epub 2015 Aug 20.

CHA Cancer Institute and Department of Biomedical Science, CHA University, CHA Bio Complex, 335 Pangyo-ro, Bundang-ku, Seongnam, Kyunggi-do 463-400, Republic of Korea.

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http://dx.doi.org/10.1038/ncomms9039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560789PMC
August 2015

Metabolomic study of carotid-femoral pulse-wave velocity in women.

J Hypertens 2015 Apr;33(4):791-6; discussion 796

aDepartment of Twin Research and Genetic Epidemiology bDepartment of Clinical Pharmacology, King's College London, London, UK cPfizer Worldwide Research and Development, Cambridge, Massachusetts dEdison Pharmaceuticals, Mountain View, California eMetabalon, Inc., Durham, North Carolina, USA fInstitute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow gAcademic Rheumatology, University of Nottingham, Nottingham, UK.

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http://dx.doi.org/10.1097/HJH.0000000000000467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354457PMC
April 2015

Uremic solutes and risk of end-stage renal disease in type 2 diabetes: metabolomic study.

Kidney Int 2014 May 15;85(5):1214-24. Epub 2014 Jan 15.

1] Section on Genetics and Epidemiology, Research Division, Joslin Diabetes Center, Boston, Massachussetts, USA [2] Department of Medicine, Harvard Medical School, Boston, Massachussetts, USA.

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http://dx.doi.org/10.1038/ki.2013.497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072128PMC
May 2014

Metabolomics in pneumonia and sepsis: an analysis of the GenIMS cohort study.

Intensive Care Med 2013 Aug 15;39(8):1423-34. Epub 2013 May 15.

Department of Critical Care Medicine and Emergency Medicine, University of Pittsburgh School of Medicine, 3550 Terrace St, Scaife Hall, #639, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.1007/s00134-013-2935-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932707PMC
August 2013

Paraoxonase-1 deficiency is associated with severe liver steatosis in mice fed a high-fat high-cholesterol diet: a metabolomic approach.

J Proteome Res 2013 Apr 8;12(4):1946-55. Epub 2013 Mar 8.

Unitat de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili , Reus, Spain.

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http://dx.doi.org/10.1021/pr400050uDOI Listing
April 2013

Autophagy: resetting glutamine-dependent metabolism and oxygen consumption.

Autophagy 2012 Oct 21;8(10):1477-93. Epub 2012 Aug 21.

Department of Molecular Pharmacology, Irell & Manella Graduate School of Biological Sciences, Beckman Research Institute, City of Hope, Duarte, CA, USA.

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http://dx.doi.org/10.4161/auto.21228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679231PMC
October 2012

Phospho-ΔNp63α/SREBF1 protein interactions: bridging cell metabolism and cisplatin chemoresistance.

Cell Cycle 2012 Oct 5;11(20):3810-27. Epub 2012 Sep 5.

Department of Dermatology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.4161/cc.22022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495824PMC
October 2012

Oncogene-induced senescence results in marked metabolic and bioenergetic alterations.

Cell Cycle 2012 Apr 1;11(7):1383-92. Epub 2012 Apr 1.

Center for Molecular Medicine, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.4161/cc.19800DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350879PMC
April 2012

Coordination of the transcriptome and metabolome by the circadian clock.

Proc Natl Acad Sci U S A 2012 Apr 19;109(14):5541-6. Epub 2012 Mar 19.

Department of Biological Chemistry, Center for Epigenetics and Metabolism, University of California, Irvine, CA 92697, USA.

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http://dx.doi.org/10.1073/pnas.1118726109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325727PMC
April 2012

Intersectin regulates epidermal growth factor receptor endocytosis, ubiquitylation, and signaling.

Mol Pharmacol 2006 Nov 16;70(5):1643-53. Epub 2006 Aug 16.

Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, USA.

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http://dx.doi.org/10.1124/mol.106.028274DOI Listing
November 2006

Discovery of highly selective inhibitors of p38alpha.

Curr Top Med Chem 2005 ;5(10):941-51

Amphora Discovery Corporation, P.O. Box 12169, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.2174/1568026054985867DOI Listing
January 2006

The U-box ligase carboxyl-terminus of Hsc 70-interacting protein ubiquitylates Epsin.

Biochem Biophys Res Commun 2005 Mar;328(2):550-9

Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, NC 27709, USA.

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http://dx.doi.org/10.1016/j.bbrc.2005.01.022DOI Listing
March 2005

Intersectin activates Ras but stimulates transcription through an independent pathway involving JNK.

J Biol Chem 2003 Nov 11;278(47):47038-45. Epub 2003 Sep 11.

Laboratory of Signal Transduction, National Institute of Environmental Health Services, NIH/DHHS, Building 101, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.1074/jbc.M303895200DOI Listing
November 2003

The genetics of febrile seizures and related epilepsy syndromes.

Brain Dev 2003 Aug;25(5):304-12

Department of Pediatrics, School of Medicine, Fukuoka University, 45-1, 7-chome Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan.

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http://dx.doi.org/10.1016/s0387-7604(03)00026-3DOI Listing
August 2003

The ubiquitin-interacting motifs target the endocytic adaptor protein epsin for ubiquitination.

Curr Biol 2002 Jul;12(13):1112-6

Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.1016/s0960-9822(02)00900-4DOI Listing
July 2002