Publications by authors named "Robert McFarland"

100Publications

Ultrasensitive deletion detection links mitochondrial DNA replication, disease, and aging.

Genome Biol 2020 Sep 17;21(1):248. Epub 2020 Sep 17.

Genome Integrity and Structural Biology Laboratory, Mitochondrial DNA Replication Group, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, 27709, USA.

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http://dx.doi.org/10.1186/s13059-020-02138-5DOI Listing
September 2020

A novel, pathogenic dinucleotide deletion in the mitochondrial MT-TY gene causing myasthenia-like features.

Neuromuscul Disord 2020 Aug 24;30(8):661-668. Epub 2020 Jun 24.

Wellcome Centre for Mitochondrial Research, The Medical School, Newcastle University, Newcastle upon Tyne, UK; NHS Highly Specialised Service for Rare Mitochondrial Disorders, Newcastle upon Tyne, UK; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1016/j.nmd.2020.06.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477489PMC
August 2020

Measuring the effects of exercise in neuromuscular disorders: a systematic review and meta-analyses.

Wellcome Open Res 2020 4;5:84. Epub 2020 May 4.

Wellcome Centre for Mitochondrial Research, Newcastle University, Newcastle Upon Tyne, Tyne and Wear, NE2 4HH, UK.

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http://dx.doi.org/10.12688/wellcomeopenres.15825.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331112PMC
May 2020

The m.15043G > A MT-CYB variant is not a pathogenic mtDNA variant.

J Neurol Sci 2020 Oct 29;417:116950. Epub 2020 May 29.

Wellcome Centre for Mitochondrial Research, Newcastle University, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK; NHS Highly Specialised Service for Rare Mitochondrial Disorders, Royal Victoria Infirmary, Newcastle upon Tyne Hospitals NHS Foundation Trust, Queen Victoria Road, Newcastle upon Tyne, NE1 4LP, UK.

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http://dx.doi.org/10.1016/j.jns.2020.116950DOI Listing
October 2020

A novel de novo ACTA1 variant in a patient with nemaline myopathy and mitochondrial Complex I deficiency.

Neuromuscul Disord 2020 02 1;30(2):159-164. Epub 2019 Dec 1.

Department of Paediatric Neurology, University Hospitals Bristol NHS Foundation Trust, 6th Floor Education Centre, Upper Maudlin St, Bristol BS2 8BJ, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.nmd.2019.11.014DOI Listing
February 2020

Pathogenic Bi-allelic Mutations in NDUFAF8 Cause Leigh Syndrome with an Isolated Complex I Deficiency.

Am J Hum Genet 2020 01 19;106(1):92-101. Epub 2019 Dec 19.

Wellcome Centre for Mitochondrial Research, Newcastle University, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK; NHS Highly Specialised Services for Rare Mitochondrial Disorders, Royal Victoria Infirmary, Newcastle upon Tyne Hospitals NHS Foundation Trust, Queen Victoria Road, Newcastle upon Tyne, NE1 4LP, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2019.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042492PMC
January 2020

Resolving complexity in mitochondrial disease: Towards precision medicine.

Mol Genet Metab 2019 Sep - Oct;128(1-2):19-29. Epub 2019 Sep 14.

Wellcome Centre for Mitochondrial Research, Institute of Neuroscience, The Medical School, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.

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http://dx.doi.org/10.1016/j.ymgme.2019.09.003DOI Listing
April 2020

Cognitive deficits in adult m.3243A>G- and m.8344A>G-related mitochondrial disease: importance of correcting for baseline intellectual ability.

Ann Clin Transl Neurol 2019 May 27;6(5):826-836. Epub 2019 Mar 27.

Wellcome Centre for Mitochondrial Research Institute of Neuroscience Newcastle University Newcastle upon Tyne NE2 4HH United Kingdom.

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http://dx.doi.org/10.1002/acn3.736DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529924PMC
May 2019

Mitochondrial Donation - Which Women Could Benefit?

N Engl J Med 2019 05;380(20):1971-1972

Newcastle University, Newcastle Upon Tyne, United Kingdom

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http://dx.doi.org/10.1056/NEJMc1808565DOI Listing
May 2019

A novel pathogenic m.4412G>A MT-TM mitochondrial DNA variant associated with childhood-onset seizures, myopathy and bilateral basal ganglia changes.

Mitochondrion 2019 07 22;47:18-23. Epub 2019 Apr 22.

Wellcome Centre for Mitochondrial Research, Institute of Neuroscience, Newcastle University, Newcastle upon Tyne NE2 4HH, UK; NHS Highly Specialised Service for Rare Mitochondrial Disorders of Adults and Children, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne NE2 4HH, UK. Electronic address:

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http://dx.doi.org/10.1016/j.mito.2019.04.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617384PMC
July 2019

Recent advances in understanding the molecular genetic basis of mitochondrial disease.

J Inherit Metab Dis 2020 01 10;43(1):36-50. Epub 2019 May 10.

Wellcome Centre for Mitochondrial Research, Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1002/jimd.12104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041634PMC
January 2020

Copy-choice recombination during mitochondrial L-strand synthesis causes DNA deletions.

Nat Commun 2019 02 15;10(1):759. Epub 2019 Feb 15.

Department of Medical Biochemistry and Cell Biology, University of Gothenburg, P.O. Box 440, Gothenburg, SE-405 30, Sweden.

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http://dx.doi.org/10.1038/s41467-019-08673-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377680PMC
February 2019

Mitochondrial donation: from test tube to clinic.

Lancet 2018 10;392(10154):1191-1192

Wellcome Centre for Mitochondrial Research, Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK; The Newcastle Upon Tyne Hospitals NHS Foundation Trust, Royal Victoria Infirmary, Queen Victoria Road, Newcastle Upon Tyne NE1 4LP, UK.

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http://dx.doi.org/10.1016/S0140-6736(18)31868-3DOI Listing
October 2018

Dissecting the neuronal vulnerability underpinning Alpers' syndrome: a clinical and neuropathological study.

Brain Pathol 2019 01 9;29(1):97-113. Epub 2018 Oct 9.

Wellcome Centre for Mitochondrial Research, Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.

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http://dx.doi.org/10.1111/bpa.12640DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379503PMC
January 2019

Phenotypic heterogeneity in m.3243A>G mitochondrial disease: The role of nuclear factors.

Ann Clin Transl Neurol 2018 03 7;5(3):333-345. Epub 2018 Feb 7.

Wellcome Centre for Mitochondrial Research Institute of Neuroscience Newcastle University Newcastle upon Tyne UK.

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http://dx.doi.org/10.1002/acn3.532DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846390PMC
March 2018

Scientific and Ethical Issues in Mitochondrial Donation.

New Bioeth 2018 Apr;24(1):57-73

a Wellcome Centre for Mitochondrial Research, Institute of Neuroscience , Newcastle University , Newcastle upon Tyne , UK.

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http://dx.doi.org/10.1080/20502877.2018.1440725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890307PMC
April 2018

The genotypic and phenotypic spectrum of MTO1 deficiency.

Mol Genet Metab 2018 01 15;123(1):28-42. Epub 2017 Nov 15.

Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada; Centre for Molecular Medicine and Therapeutics, Vancouver, BC, Canada; BC Children's Hospital Research Institute, University of British Columbia, Vancouver, Canada; Departments of Pediatrics and Clinical Genetics, Academic Medical Center, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ymgme.2017.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780301PMC
January 2018

International Workshop:: Outcome measures and clinical trial readiness in primary mitochondrial myopathies in children and adults. Consensus recommendations. 16-18 November 2016, Rome, Italy.

Neuromuscul Disord 2017 12 8;27(12):1126-1137. Epub 2017 Sep 8.

Department of Neurology, H. Houston Merritt Neuromuscular Research Center, Columbia University Medical Center, New York, NY, USA.

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http://dx.doi.org/10.1016/j.nmd.2017.08.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094160PMC
December 2017

De novo variant is associated with decreased mitochondrial respiratory chain activities.

Neurol Genet 2017 Oct 22;3(5):e187. Epub 2017 Sep 22.

Wellcome Centre for Mitochondrial Research (E.W.S., C.L.A., L.H., G.F., R.M., R.W.T.), Institute of Neuroscience, Newcastle University, United Kingdom; Department of Molecular and Human Genetics (E.W.S.), Baylor College of Medicine, Houston, TX; Wellcome Centre for Mitochondrial Research (A.P.), Institute of Genetic Medicine, Newcastle University; Armistead Child Development Centre (K.N.), Kings Cross Hospital, Dundee, Scotland; Department of Clinical Neurosciences (P.F.C.), School of Clinical Medicine, University of Cambridge; and MRC Mitochondrial Biology Unit (P.F.C.), University of Cambridge, United Kingdom.

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http://dx.doi.org/10.1212/NXG.0000000000000187DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610040PMC
October 2017

The presence of anaemia negatively influences survival in patients with POLG disease.

J Inherit Metab Dis 2017 11 1;40(6):861-866. Epub 2017 Sep 1.

Department of Clinical Medicine (K1), University of Bergen, Bergen, Norway.

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http://dx.doi.org/10.1007/s10545-017-0084-9DOI Listing
November 2017

Decreased male reproductive success in association with mitochondrial dysfunction.

Eur J Hum Genet 2017 10 16;25(10):1162-1164. Epub 2017 Aug 16.

Wellcome Trust Centre for Mitochondrial Research, The Medical School, Newcastle University, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1038/ejhg.2017.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600812PMC
October 2017

RMND1-Related Leukoencephalopathy With Temporal Lobe Cysts and Hearing Loss-Another Mendelian Mimicker of Congenital Cytomegalovirus Infection.

Pediatr Neurol 2017 01 13;66:59-62. Epub 2016 Sep 13.

Department of Neurology, Children's National Medical Center, Washington, DC; Department of Integrated Systems Biology, George Washington University, Washington, DC; Department of Pediatrics, George Washington University, Washington, DC. Electronic address:

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http://dx.doi.org/10.1016/j.pediatrneurol.2016.09.003DOI Listing
January 2017

Mitochondrial diseases.

Nat Rev Dis Primers 2016 10 20;2:16080. Epub 2016 Oct 20.

Wellcome Trust Centre for Mitochondrial Research, Institute of Neuroscience, The Medical School Framlington Place, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.

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http://dx.doi.org/10.1038/nrdp.2016.80DOI Listing
October 2016

Teaching NeuroImages: Neuroradiologic evolution of Leigh disease.

Neurology 2016 10;87(14):e159-e160

From the Wellcome Trust Centre for Mitochondrial Research (Y.S.N., R.M.), Institute of Neuroscience, Newcastle University, Newcastle upon Tyne; Evelina London Children's Hospital and Children's Neurosciences Centre, Newcomen Centre at St Thomas' Hospital (M.L.), London; and Morriston Hospital (G.T.), Abertawe Bro Morgannwg University Health Board, Wales, UK.

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http://dx.doi.org/10.1212/WNL.0000000000003182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075973PMC
October 2016

Epilepsy due to mutations in the mitochondrial polymerase gamma (POLG) gene: A clinical and molecular genetic review.

Epilepsia 2016 Oct 24;57(10):1531-1545. Epub 2016 Aug 24.

Wellcome Trust Centre for Mitochondrial Research, Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1111/epi.13508DOI Listing
October 2016

Incidence of Primary Mitochondrial Disease in Children Younger Than 2 Years Presenting With Acute Liver Failure.

J Pediatr Gastroenterol Nutr 2016 12;63(6):592-597

*Liver Unit, Birmingham Children's Hospital †University of Birmingham ‡Department of Clinical IMD §Department of Radiology, Birmingham Children's Hospital, Birmingham ||Oxford Medical Genetics Laboratories, Oxford University Hospitals NHS Foundation Trust ¶Nuffield Department of Obstetrics and Gynaecology, University of Oxford #Wellcome Trust Centre for Mitochondrial Research and Highly Specialised Rare Mitochondrial Disease Service, Newcastle University **Genetics and Genomic Medicine, UCL Institute of Child Health, London, United Kingdom.

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http://dx.doi.org/10.1097/MPG.0000000000001345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113754PMC
December 2016

Pseudo-obstruction, stroke, and mitochondrial dysfunction: A lethal combination.

Ann Neurol 2016 Nov 19;80(5):686-692. Epub 2016 Sep 19.

Wellcome Trust Centre for Mitochondrial Research, Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1002/ana.24736DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215534PMC
November 2016

International Paediatric Mitochondrial Disease Scale.

J Inherit Metab Dis 2016 09 9;39(5):705-712. Epub 2016 Jun 9.

Radboudn Center for Mitochondrial Medicine at the Department of Paediatrics, Radboudumc, Geert Grooteplein 10. 6500 HB, PO BOX 9101, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1007/s10545-016-9948-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987390PMC
September 2016

Clinical, Genetic, and Radiological Features of Extrapyramidal Movement Disorders in Mitochondrial Disease.

JAMA Neurol 2016 06;73(6):668-74

Wellcome Trust Centre for Mitochondrial Research and Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, England.

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http://dx.doi.org/10.1001/jamaneurol.2016.0355DOI Listing
June 2016

Both mitochondrial DNA and mitonuclear gene mutations cause hearing loss through cochlear dysfunction.

Brain 2016 06 25;139(Pt 6):e33. Epub 2016 Mar 25.

Department of Clinical Neuroscience, School of Clinical Medicine, University of Cambridge, Cambridge CB2 0QQ, UK Medical Research Council Mitochondrial Biology Unit, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK

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http://dx.doi.org/10.1093/brain/aww051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892749PMC
June 2016

Epilepsy in adults with mitochondrial disease: A cohort study.

Ann Neurol 2015 Dec 17;78(6):949-57. Epub 2015 Nov 17.

Wellcome Trust Center for Mitochondrial Research, Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1002/ana.24525DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737309PMC
December 2015

Causes of Death in Adults with Mitochondrial Disease.

JIMD Rep 2016 10;26:103-13. Epub 2015 Sep 10.

Wellcome Trust Centre for Mitochondrial Research, Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1007/8904_2015_449DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864865PMC
May 2016

Neuropathologic Characterization of Pontocerebellar Hypoplasia Type 6 Associated With Cardiomyopathy and Hydrops Fetalis and Severe Multisystem Respiratory Chain Deficiency due to Novel RARS2 Mutations.

J Neuropathol Exp Neurol 2015 Jul;74(7):688-703

From the Wellcome Trust Centre for Mitochondrial Research, Institute of Neuroscience, The Medical School, Newcastle University, Newcastle upon Tyne, UK (NZL, CLA, LH, GF, RM, RWT); East Anglian Medical Genetics Service, Cambridge University Hospital NHS foundations Trust, Cambridge Biomedical Campus, Cambridge, UK (KS, SP); Department of Paediatric Neurology, Addenbrooke's Hospital, Cambridge Biomedical Campus, Cambridge UK (DK); Neonatal Unit, The Rosie Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK (AO); The Centre for Fetal Care, Queen Charlotte's and Chelsea Hospital, Du Cane Road, London, UK (CL); Department of Clinical Neurosciences, Institute of Neurology, University College London, London, UK (RHK); Neurometabolic Unit, National Hospital for Neurology and Neurosurgery, London, UK (IPH); Oxford Medical Genetics Laboratories, Oxford University Hospitals NHS Trust, Oxford, UK (GKB); and Department of Histopathology, Cambridge University Hospital NHS foundations Trust, Cambridge, UK (AFD).

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http://dx.doi.org/10.1097/NEN.0000000000000209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470523PMC
July 2015

Preliminary Evaluation of Clinician Rated Outcome Measures in Mitochondrial Disease.

J Neuromuscul Dis 2015 Jun;2(2):151-155

Wellcome Trust Centre for Mitochondrial Research Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.

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http://dx.doi.org/10.3233/JND-140061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5271457PMC
June 2015

Perceived fatigue is highly prevalent and debilitating in patients with mitochondrial disease.

Neuromuscul Disord 2015 Jul 23;25(7):563-6. Epub 2015 Apr 23.

Wellcome Trust Centre for Mitochondrial Research, Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne NE2 4HH, UK; Institute of Ageing and Health and NIHR Biomedical Research Centre for Ageing, Newcastle University, Newcastle upon Tyne NE4 5PL, UK.

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http://dx.doi.org/10.1016/j.nmd.2015.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502433PMC
July 2015

The GABA transaminase, ABAT, is essential for mitochondrial nucleoside metabolism.

Cell Metab 2015 Mar;21(3):417-27

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2015.02.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757431PMC
March 2015

Prevalence of nuclear and mitochondrial DNA mutations related to adult mitochondrial disease.

Ann Neurol 2015 May 28;77(5):753-9. Epub 2015 Mar 28.

Wellcome Centre for Mitochondrial Research, Newcastle University, Newcastle upon Tyne, United Kingdom; Institute of Neuroscience, Henry Wellcome Building for Neuroecology, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1002/ana.24362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737121PMC
May 2015

Clonal expansion of secondary mitochondrial DNA deletions associated with spinocerebellar ataxia type 28.

JAMA Neurol 2015 Jan;72(1):106-11

Wellcome Centre for Mitochondrial Research, Newcastle University, Newcastle upon Tyne, England2Institute for Ageing and Health, National Institute for Health Research Biomedical Research Centre for Ageing, Newcastle University, Newcastle upon Tyne, Englan.

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http://dx.doi.org/10.1001/jamaneurol.2014.1753DOI Listing
January 2015

The urinary proteome and metabonome differ from normal in adults with mitochondrial disease.

Kidney Int 2015 Mar 10;87(3):610-22. Epub 2014 Sep 10.

Medical Research Council Centre for Neuromuscular Diseases, National Hospital for Neurology and Neurosurgery, University College London Institute of Neurology, London, UK.

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http://dx.doi.org/10.1038/ki.2014.297DOI Listing
March 2015

Mitochondrial myopathies in adults and children: management and therapy development.

Curr Opin Neurol 2014 Oct;27(5):576-82

aDepartment of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London bWellcome Trust Centre for Mitochondrial Research, Newcastle University and NUTH NHS Foundation Trust, Newcastle upon Tyne, UK.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/WCO.0000000000000126DOI Listing
October 2014

A national perspective on prenatal testing for mitochondrial disease.

Eur J Hum Genet 2014 Nov 19;22(11):1255-9. Epub 2014 Mar 19.

1] Wellcome Trust Centre for Mitochondrial Research, The Medical School, Institute for Ageing and Health, Newcastle University, Newcastle-upon-Tyne, UK [2] NHS Specialised Services for Rare Mitochondrial Disorders of Adults and Children UK, Oxford, UK.

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http://dx.doi.org/10.1038/ejhg.2014.35DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200441PMC
November 2014

Disease progression in patients with single, large-scale mitochondrial DNA deletions.

Brain 2014 Feb 25;137(Pt 2):323-34. Epub 2013 Nov 25.

1 Wellcome Trust Centre for Mitochondrial Research, Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1093/brain/awt321DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914470PMC
February 2014

Mutation of the human mitochondrial phenylalanine-tRNA synthetase causes infantile-onset epilepsy and cytochrome c oxidase deficiency.

Biochim Biophys Acta 2014 Jan 24;1842(1):56-64. Epub 2013 Oct 24.

Wellcome Trust Centre for Mitochondrial Research, Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne NE2 4HH, UK. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2013.10.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898479PMC
January 2014

Discrete gait characteristics are associated with m.3243A>G and m.8344A>G variants of mitochondrial disease and its pathological consequences.

J Neurol 2014 Jan 23;261(1):73-82. Epub 2013 Oct 23.

Clinical Ageing Research Unit, Campus for Ageing and Vitality, Institute for Ageing and Health, Newcastle University, Newcastle Upon Tyne, UK,

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http://dx.doi.org/10.1007/s00415-013-7129-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895207PMC
January 2014