Robert M Bachoo

Robert M Bachoo

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Robert M Bachoo

Robert M Bachoo

Publications by authors named "Robert M Bachoo"

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Isotope Tracing of Human Clear Cell Renal Cell Carcinomas Demonstrates Suppressed Glucose Oxidation In Vivo.

Cell Metab 2018 11 23;28(5):793-800.e2. Epub 2018 Aug 23.

Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA; Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX, USA; Annette G. Strauss Center for Neuro-Oncology, University of Texas Southwestern Medical Center, Dallas, TX, USA; Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2018.07.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221993PMC
November 2018

Targeting orthotopic gliomas with renal-clearable luminescent gold nanoparticles.

Nano Res 2017 Apr 21;10(4):1366-1376. Epub 2017 Feb 21.

Department of Chemistry and Biochemistry, The University of Texas at Dallas, Richardson, TX 75080, USA.

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http://dx.doi.org/10.1007/s12274-017-1472-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639726PMC
April 2017

Oncogenes Activate an Autonomous Transcriptional Regulatory Circuit That Drives Glioblastoma.

Cell Rep 2017 01;18(4):961-976

Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Annette G. Strauss Center for Neuro-Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.12.064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321610PMC
January 2017

Hepatic gluconeogenesis influences (13)C enrichment in lactate in human brain tumors during metabolism of [1,2-(13)C]acetate.

Neurochem Int 2016 07 26;97:133-6. Epub 2016 Mar 26.

Simmons Cancer Center, UT Southwestern Medical Center, Dallas, TX 75390, USA; Annette G. Strauss Center for Neuro-Oncology, UT Southwestern Medical Center, Dallas, TX 75390, USA; Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX 75390, USA; Department of Neurology and Neurotherapeutics, UT Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1016/j.neuint.2016.03.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951105PMC
July 2016

Proton T2 measurement and quantification of lactate in brain tumors by MRS at 3 Tesla in vivo.

Magn Reson Med 2015 Jun 7;73(6):2094-9. Epub 2014 Jul 7.

Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

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http://dx.doi.org/10.1002/mrm.25352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286522PMC
June 2015

¹H MRS characterization of neurochemical profiles in orthotopic mouse models of human brain tumors.

NMR Biomed 2015 Jan 13;28(1):108-15. Epub 2014 Nov 13.

Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX, USA; Department of Radiology, University of Texas Southwestern Medical Center, Dallas, TX, USA.

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http://doi.wiley.com/10.1002/nbm.3231
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http://dx.doi.org/10.1002/nbm.3231DOI Listing
January 2015

Acetate is a bioenergetic substrate for human glioblastoma and brain metastases.

Cell 2014 Dec;159(7):1603-14

Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX 75390, USA; Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX 75390, USA; Annette G. Strauss Center for Neuro-Oncology, UT Southwestern Medical Center, Dallas, TX 75390, USA; Department of Neurology and Neurotherapeutics, UT Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2014.11.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374602PMC
December 2014

In vivo detection of citrate in brain tumors by 1H magnetic resonance spectroscopy at 3T.

Magn Reson Med 2014 Aug 1;72(2):316-23. Epub 2013 Oct 1.

Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, Texas, USA; Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA; Harold C. Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

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http://dx.doi.org/10.1002/mrm.24946DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236907PMC
August 2014

In vivo chemical exchange saturation transfer imaging allows early detection of a therapeutic response in glioblastoma.

Proc Natl Acad Sci U S A 2014 Mar 10;111(12):4542-7. Epub 2014 Mar 10.

Advanced Imaging Research Center, Department of Internal Medicine, Harold C. Simmons Comprehensive Cancer Center, and Departments of Neurology and Neurotherapeutics, Pathology, Neurosurgery, and Radiology, University of Texas Southwestern Medical Center, Dallas, TX 75390.

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http://dx.doi.org/10.1073/pnas.1323855111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970489PMC
March 2014

Small-molecule blocks malignant astrocyte proliferation and induces neuronal gene expression.

Differentiation 2011 Apr 17;81(4):233-42. Epub 2011 Mar 17.

Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1016/j.diff.2011.02.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3752777PMC
April 2011

Glioblastoma cells require glutamate dehydrogenase to survive impairments of glucose metabolism or Akt signaling.

Cancer Res 2009 Oct 13;69(20):7986-93. Epub 2009 Oct 13.

Department of Pediatrics, McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center at Dallas, Texas 75390-9063, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-2266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764330PMC
October 2009

Functional skeletal muscle regeneration from differentiating embryonic stem cells.

Nat Med 2008 Feb 20;14(2):134-43. Epub 2008 Jan 20.

Department of Developmental Biology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390-9133, USA.

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http://dx.doi.org/10.1038/nm1705DOI Listing
February 2008

Identification of a PTEN-regulated STAT3 brain tumor suppressor pathway.

Genes Dev 2008 Feb 7;22(4):449-62. Epub 2008 Feb 7.

Department of Pathology, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1101/gad.1606508DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2238667PMC
February 2008

Malignant astrocytic glioma: genetics, biology, and paths to treatment.

Genes Dev 2007 Nov;21(21):2683-710

Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, California 92093, USA.

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http://dx.doi.org/10.1101/gad.1596707DOI Listing
November 2007

PCAF modulates PTEN activity.

J Biol Chem 2006 Sep 7;281(36):26562-8. Epub 2006 Jul 7.

Ludwig Institute for Cancer Research, San Diego Branch, CA, USA.

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http://dx.doi.org/10.1074/jbc.M605391200DOI Listing
September 2006

Molecular diversity of astrocytes with implications for neurological disorders.

Proc Natl Acad Sci U S A 2004 Jun 21;101(22):8384-9. Epub 2004 May 21.

Department of Medical Oncology , Dana-Farber Cancer Institute, 44 Binney Street, Boston, MA 02115, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0402140101
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http://dx.doi.org/10.1073/pnas.0402140101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC420403PMC
June 2004

Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing.

Nature 2003 Feb 22;421(6923):643-8. Epub 2003 Jan 22.

Department of Adult Oncology, Dana Farber Cancer Institute Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/nature01385DOI Listing
February 2003