Robert Lipsky, PhD - Inova Neuroscience Institute - Director of Translational Research

Robert Lipsky

PhD

Inova Neuroscience Institute

Director of Translational Research

Fairfax, VA | United States

Main Specialties: Addiction Psychiatry, Biochemical Genetics, Medical Genetics, Molecular Genetic Pathology, Neurology

ORCID logohttps://orcid.org/0000-0001-7753-1473

Robert Lipsky, PhD - Inova Neuroscience Institute - Director of Translational Research

Robert Lipsky

PhD

Education

Aug 1979 - Aug 1983
Cornell University
Ph.D.
Genetics and Development

Experience

Nov 2008
Inova Health System
Director of Translational Research
Neurosciences

Publications

71Publications

1171Reads

1Profile Views

1636PubMed Central Citations

PHASES score applied to a prospective cohort of aneurysmal subarachnoid hemorrhage patients.

J Clin Neurosci 2018 Jul 20;53:69-73. Epub 2018 Apr 20.

Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States; Department of Neurosurgery, Geisinger Health System, Danville, PA, United States; Department of Neurosurgery, Paracelsus Medical University, Salzburg, Austria; Research Institute of Neurointervention, Paracelsus Medical University, Salzburg, Austria.

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http://dx.doi.org/10.1016/j.jocn.2018.04.014DOI Listing
July 2018
5 Reads
1.320 Impact Factor

Association of cystathionine beta-synthase polymorphisms and aneurysmal subarachnoid hemorrhage.

J Neurosurg 2018 06 4;128(6):1771-1777. Epub 2017 Aug 4.

8Neurosurgical Service, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts; and.

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http://dx.doi.org/10.3171/2017.2.JNS162933DOI Listing
June 2018
17 Reads
3.740 Impact Factor

The role of endothelial nitric oxide synthase -786 T/C polymorphism in cardiac instability following aneurysmal subarachnoid hemorrhage.

Nitric Oxide 2017 Dec 24;71:52-56. Epub 2017 Oct 24.

Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States; Department of Neurosurgery, Geisinger Health System, Danville, PA, United States.

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http://dx.doi.org/10.1016/j.niox.2017.10.008DOI Listing
December 2017
19 Reads
3.521 Impact Factor

Association of Plasminogen Activator Inhibitor 1 (SERPINE1) Polymorphisms and Aneurysmal Subarachnoid Hemorrhage.

World Neurosurg 2017 Sep 6;105:672-677. Epub 2017 Jun 6.

Department of Neurosurgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA; Department of Neurosurgery, Geisinger Health System, Danville, Pennsylvania, USA.

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http://dx.doi.org/10.1016/j.wneu.2017.05.175DOI Listing
September 2017
30 Reads
1 Citation
2.420 Impact Factor

Stress-Related Mental Health Symptoms in Coast Guard: Incidence, Vulnerability, and Neurocognitive Performance.

Front Psychol 2017 14;8:1513. Epub 2017 Sep 14.

Department of Neurology, University of Tennessee Health Science CenterMemphis, TN, United States.

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http://dx.doi.org/10.3389/fpsyg.2017.01513DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603677PMC
September 2017
56 Reads
1 Citation

Corrigendum to 'Predictors of Shunt Insertion in Aneurysmal Subarachnoid Hemorrhage' [World Neurosurgery 98 (2017) 421-426].

World Neurosurg 2017 08 17;104:1043. Epub 2017 Jun 17.

Neurosurgery Service, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA. Electronic address:

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http://dx.doi.org/10.1016/j.wneu.2017.06.021DOI Listing
August 2017
28 Reads
2.420 Impact Factor

Associations of Endothelin Polymorphisms and Aneurysm Size at Time of Rupture.

World Neurosurg 2017 Jun 18;102:253-257. Epub 2017 Mar 18.

Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA; Department of Neurosurgery, Geisinger Health System, Danville, Pennsylvania, USA.

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http://dx.doi.org/10.1016/j.wneu.2017.03.041DOI Listing
June 2017
21 Reads
2.420 Impact Factor

Impact of High-Mobility Group Box 1 Polymorphism on Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage.

World Neurosurg 2017 May 10;101:325-330. Epub 2017 Feb 10.

Neurosurgical Service, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA; Department of Neurosurgery, Geisinger Health System, Danville, Pennsylvania, USA.

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http://dx.doi.org/10.1016/j.wneu.2017.01.121DOI Listing
May 2017
48 Reads
3 Citations
2.420 Impact Factor

Endothelial Nitric Oxide Synthase Polymorphism Is Associated with Delayed Cerebral Ischemia Following Aneurysmal Subarachnoid Hemorrhage.

World Neurosurg 2017 May 22;101:514-519. Epub 2017 Feb 22.

Neurosurgical Service, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA; Department of Neurosurgery, Geisinger Health System, Danville, Pennsylvania, USA.

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http://dx.doi.org/10.1016/j.wneu.2017.02.062DOI Listing
May 2017
15 Reads
1 Citation
2.420 Impact Factor

Ryanodine Receptor 1 Polymorphism Is Not Associated with Aneurysmal Subarachnoid Hemorrhage or its Clinical Sequelae.

World Neurosurg 2017 Apr 10;100:190-194. Epub 2017 Jan 10.

Neurosurgical Service, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA; Department of Neurosurgery, Geisinger Health System, Danville, Pennsylvania, USA.

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http://dx.doi.org/10.1016/j.wneu.2016.12.132DOI Listing
April 2017
34 Reads
2.420 Impact Factor

Functional human promoter polymorphism and variation of mental processing speed in older adults.

Aging (Albany NY) 2017 04;9(4):1293-1306

Department of Molecular Neuroscience, the Krasnow Institute for Advanced Study, George Mason University, Fairfax, VA 22030, USA.

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http://dx.doi.org/10.18632/aging.101228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425128PMC
April 2017
76 Reads
6.432 Impact Factor

Predictors of Shunt Insertion in Aneurysmal Subarachnoid Hemorrhage.

World Neurosurg 2017 02 24;98:421-426. Epub 2016 Nov 24.

Neurosurgery Service, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA. Electronic address:

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http://dx.doi.org/10.1016/j.wneu.2016.11.092DOI Listing
February 2017
36 Reads
2.420 Impact Factor

Association of nosocomial infections with delayed cerebral ischemia in aneurysmal subarachnoid hemorrhage.

J Neurosurg 2016 12 12;125(6):1383-1389. Epub 2016 Feb 12.

Department of Neurosurgery, University of Alabama at Birmingham, Alabama.

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http://dx.doi.org/10.3171/2015.10.JNS151959DOI Listing
December 2016
51 Reads
1 Citation
3.740 Impact Factor

Genetic predictors of outcome following traumatic brain injury.

Handb Clin Neurol 2015 ;127:23-41

Department of Molecular Neuroscience, Krasnow Institute for Advanced Study, George Mason University, Fairfax, VA, USA.

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http://dx.doi.org/10.1016/B978-0-444-52892-6.00003-9DOI Listing
August 2016
2 Reads
3 Citations

Alpha-linolenic acid: an omega-3 fatty acid with neuroprotective properties-ready for use in the stroke clinic?

Biomed Res Int 2015 19;2015:519830. Epub 2015 Feb 19.

Department of Neurology and Program in Neuroscience, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814, USA.

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http://dx.doi.org/10.1155/2015/519830DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350958PMC
November 2015
8 Reads
5 Citations

Epigenetics of depression.

Prog Mol Biol Transl Sci 2014 ;128:103-37

Inova Neurosciences Institute, Inova Health System, Falls Church, Virginia, USA; Department of Molecular Neuroscience, The Krasnow Institute for Advanced Study, George Mason University, Fairfax, Virginia, USA.

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http://dx.doi.org/10.1016/B978-0-12-800977-2.00005-XDOI Listing
August 2015
6 Reads
8 Citations
3.490 Impact Factor

Repeated ketamine administration alters N-methyl-D-aspartic acid receptor subunit gene expression: implication of genetic vulnerability for ketamine abuse and ketamine psychosis in humans.

Exp Biol Med (Maywood) 2015 Feb 21;240(2):145-55. Epub 2014 Sep 21.

Inova Neuroscience Institute, Inova Health System, Falls Church, VA 22042, USA Department of Molecular Neuroscience, the Krasnow Institute for Advanced Study, George Mason University, Fairfax, VA 22030, USA.

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http://dx.doi.org/10.1177/1535370214549531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469194PMC
February 2015
15 Reads
3 Citations

Epigenetic mechanisms regulating learning and long-term memory.

Authors:
Robert H Lipsky

Int J Dev Neurosci 2013 Oct 6;31(6):353-8. Epub 2012 Nov 6.

Inova Neuroscience Institute, Department of Neurosciences, Inova Health System, 3289 Woodburn Road, Suite 210B, Annandale, VA 22003, United States.

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http://dx.doi.org/10.1016/j.ijdevneu.2012.10.110DOI Listing
October 2013
2 Reads
7 Citations
2.580 Impact Factor

CD28-inducible transcription factor DEC1 is required for efficient autoreactive CD4+ T cell response.

J Exp Med 2013 Jul 22;210(8):1603-19. Epub 2013 Jul 22.

Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1084/jem.20122387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3727315PMC
July 2013
36 Reads
23 Citations
12.520 Impact Factor

BDNF polymorphism-dependent OFC and DLPFC plasticity differentially moderates implicit and explicit bias.

Cereb Cortex 2012 Nov 28;22(11):2602-9. Epub 2011 Nov 28.

Imaging Sciences Training Program, Radiology and Imaging Sciences, Clinical Center and National Institute of Biomedical Imaging and Bioengineering, National, Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1093/cercor/bhr337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464413PMC
November 2012
9 Reads
5 Citations
8.665 Impact Factor

Oxytocin receptor genetic variation promotes human trust behavior.

Front Hum Neurosci 2012 2;6. Epub 2012 Feb 2.

Department of Molecular Neuroscience, George Mason University Fairfax, VA, USA.

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http://dx.doi.org/10.3389/fnhum.2012.00004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270329PMC
October 2012
1 Read
39 Citations
2.900 Impact Factor

Cellular and molecular responses of cultured neurons to stressful stimuli.

Dose Response 2011 22;9(3):416-33. Epub 2011 Feb 22.

Uniformed Services University of the Health Sciences, Department of Neurology and Program in Neuroscience, 4301 Jones Bridge Road, Bethesda, Maryland 20814.

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http://dx.doi.org/10.2203/dose-response.10-041.MariniDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186935PMC
November 2011
1 Read
1 Citation
1.234 Impact Factor

Effects of histone deacetylase inhibitor Trichostatin A on epigenetic changes and transcriptional activation of Bdnf promoter 1 by rat hippocampal neurons.

Ann N Y Acad Sci 2010 Jun;1199:186-93

Section on Cancer Genetics, Genetics Branch, National Cancer Institute, NIH, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1111/j.1749-6632.2009.05175.xDOI Listing
June 2010
18 Reads
15 Citations
4.313 Impact Factor

NMDA receptor activation induces differential epigenetic modification of Bdnf promoters in hippocampal neurons.

Amino Acids 2010 Apr 30;38(4):1067-74. Epub 2009 Jun 30.

Section on Cancer Genetics, Genetics Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1007/s00726-009-0315-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2850947PMC
April 2010
12 Reads
12 Citations
3.293 Impact Factor

Subchronic alpha-linolenic acid treatment enhances brain plasticity and exerts an antidepressant effect: a versatile potential therapy for stroke.

Neuropsychopharmacology 2009 Nov 29;34(12):2548-59. Epub 2009 Jul 29.

Cerebrovascular Pathologies and Therapeutic Laboratory, Institut de Pharmacologie Moléculaires et Cellulaires - UMR6097, C.N.R.S, Valbonne, France.

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http://dx.doi.org/10.1038/npp.2009.84DOI Listing
November 2009
45 Reads
20 Citations
7.050 Impact Factor

Dynamic chromatin remodeling events in hippocampal neurons are associated with NMDA receptor-mediated activation of Bdnf gene promoter 1.

J Neurochem 2009 Jun 23;109(5):1375-88. Epub 2009 Mar 23.

Section on Molecular Genetics, Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland, USA.

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http://doi.wiley.com/10.1111/j.1471-4159.2009.06058.x
Publisher Site
http://dx.doi.org/10.1111/j.1471-4159.2009.06058.xDOI Listing
June 2009
60 Reads
24 Citations
4.281 Impact Factor

Human BDNF isoforms are differentially expressed in cocaine addicts and are sorted to the regulated secretory pathway independent of the Met66 substitution.

Neuromolecular Med 2009 23;11(1):1-12. Epub 2008 Oct 23.

Section on Molecular Genetics, Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, 5625 Fishers Lane, Bethesda, MD 20892-9412, USA.

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http://dx.doi.org/10.1007/s12017-008-8051-0DOI Listing
April 2009
6 Reads
6 Citations
3.680 Impact Factor

A missense variant (P10L) of the melanopsin (OPN4) gene in seasonal affective disorder.

J Affect Disord 2009 Apr 18;114(1-3):279-85. Epub 2008 Sep 18.

Graduate Program in Medical Psychology, Uniformed Services University of the Health Sciences, Bethesda, MD, United States.

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http://dx.doi.org/10.1016/j.jad.2008.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647333PMC
April 2009
4 Reads
38 Citations
3.383 Impact Factor

Additional functional variation at the SLC6A4 gene.

Am J Med Genet B Neuropsychiatr Genet 2009 Jan;150B(1):153

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http://dx.doi.org/10.1002/ajmg.b.30766DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716041PMC
January 2009
6 Citations
3.420 Impact Factor

Variation in the genes encoding vesicular monoamine transporter 2 and beta-1 adrenergic receptor and antidepressant treatment outcome.

Psychiatr Genet 2008 Oct;18(5):248-51

Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1097/YPG.0b013e3283052ff7DOI Listing
October 2008
5 Reads
2 Citations
1.941 Impact Factor

Brain adaptation to stressful stimuli: a new perspective on potential therapeutic approaches based on BDNF and NMDA receptors.

CNS Neurol Disord Drug Targets 2008 Oct;7(4):382-90

Department of Neurology and Neuroscience Program, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA.

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http://dx.doi.org/10.2174/187152708786441849DOI Listing
October 2008
8 Reads
9 Citations
2.630 Impact Factor

CRH haplotype as a factor influencing cerebrospinal fluid levels of corticotropin-releasing hormone, hypothalamic-pituitary-adrenal axis activity, temperament, and alcohol consumption in rhesus macaques.

Arch Gen Psychiatry 2008 Aug;65(8):934-44

Laboratory of Clinical Studies, Primate Section, National Institute on Alcohol Abuse Alcoholism, Division of Intramural Clinical and Biological Research, TR 112, PO Box 529, Poolesville, MD 20837, USA.

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http://dx.doi.org/10.1001/archpsyc.65.8.934DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688441PMC
August 2008
19 Reads
33 Citations
14.480 Impact Factor

Demographic, structural and genetic predictors of late cognitive decline after penetrating head injury.

Brain 2008 Feb 19;131(Pt 2):543-58. Epub 2007 Dec 19.

Vietnam Head Injury Study, Henry M. Jackson Foundation, National Naval Medical Center, Bethesda, MD 20889, USA.

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http://brain.oxfordjournals.org/content/brain/131/2/543.full
Web Search
http://www.brain.oxfordjournals.org/cgi/doi/10.1093/brain/aw
Publisher Site
http://dx.doi.org/10.1093/brain/awm300DOI Listing
February 2008
2 Reads
24 Citations
9.200 Impact Factor

Hormesis: a promising strategy to sustain endogenous neuronal survival pathways against neurodegenerative disorders.

Ageing Res Rev 2008 Jan 24;7(1):21-33. Epub 2007 Aug 24.

Department of Neurology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.

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http://dx.doi.org/10.1016/j.arr.2007.07.003DOI Listing
January 2008
7 Reads
7 Citations
4.940 Impact Factor

BHLHB2 controls Bdnf promoter 4 activity and neuronal excitability.

J Neurosci 2008 Jan;28(5):1118-30

Section on Molecular Genetics, Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.2262-07.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6671398PMC
January 2008
5 Reads
33 Citations
6.344 Impact Factor

Brain-derived neurotrophic factor in neuronal survival and behavior-related plasticity.

Ann N Y Acad Sci 2007 Dec;1122:130-43

Section of Molecular Genetics, Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20814, USA.

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http://dx.doi.org/10.1196/annals.1403.009DOI Listing
December 2007
73 Citations
4.313 Impact Factor

Association of GRIK4 with outcome of antidepressant treatment in the STAR*D cohort.

Am J Psychiatry 2007 Aug;164(8):1181-8

Genetic Basis of Mood and Anxiety Disorders, Mood and Anxiety Program, NIMH, NIH, Department of Health and Human Services, Bethesda, MD, USA.

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http://dx.doi.org/10.1176/appi.ajp.2007.06111790DOI Listing
August 2007
8 Reads
53 Citations
12.295 Impact Factor

Association between a functional serotonin transporter promoter polymorphism and citalopram treatment in adult outpatients with major depression.

Arch Gen Psychiatry 2007 Jul;64(7):783-92

Section on Molecular Genetics, Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1001/archpsyc.64.7.783DOI Listing
July 2007
8 Reads
47 Citations
14.480 Impact Factor

Variation in the gene encoding the serotonin 2A receptor is associated with outcome of antidepressant treatment.

Am J Hum Genet 2006 May 20;78(5):804-814. Epub 2006 Mar 20.

Laboratory of Molecular Pathophysiology, Mood and Anxiety Program, National Institute of Mental Health (NIMH), National Institutes of Health (NIH), Department of Health and Human Services (DHHS), Bethesda.

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http://dx.doi.org/10.1086/503820DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1474035PMC
May 2006
19 Reads
100 Citations
10.931 Impact Factor

Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder.

Am J Hum Genet 2006 May 28;78(5):815-826. Epub 2006 Mar 28.

Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, Rockville, MD. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029297076381
Publisher Site
http://dx.doi.org/10.1086/503850DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1474042PMC
May 2006
3 Reads
324 Citations
10.931 Impact Factor

Association of COMT Val158Met genotype with executive functioning following traumatic brain injury.

J Neuropsychiatry Clin Neurosci 2005 ;17(4):465-71

Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Rockville, MD, USA.

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http://dx.doi.org/10.1176/jnp.17.4.465DOI Listing
February 2006
4 Reads
26 Citations
2.820 Impact Factor

Delineating and understanding cerebellar neuroprotective pathways: potential implication for protecting the cortex.

Ann N Y Acad Sci 2005 Aug;1053:39-47

Department of Neurology, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA.

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http://dx.doi.org/10.1196/annals.1344.004DOI Listing
August 2005
7 Reads
2 Citations
4.313 Impact Factor

The excitoprotective effect of N-methyl-D-aspartate receptors is mediated by a brain-derived neurotrophic factor autocrine loop in cultured hippocampal neurons.

J Neurochem 2005 Aug 5;94(3):713-22. Epub 2005 Jul 5.

Department of Neurology and Division of Neuroscience, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2005.03200.xDOI Listing
August 2005
34 Reads
36 Citations
4.281 Impact Factor

BDNF variation and mood disorders: a novel functional promoter polymorphism and Val66Met are associated with anxiety but have opposing effects.

Neuropsychopharmacology 2005 Jul;30(7):1353-61

Section on Molecular Genetics, Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1038/sj.npp.1300703DOI Listing
July 2005
10 Reads
59 Citations
7.050 Impact Factor

Inhibition of protein kinase C promotes neuronal survival in low potassium through an Akt-dependent pathway.

Neurotox Res 2004 ;6(4):281-9

Department of Neurology and Neuroscience, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.

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http://dx.doi.org/10.1007/BF03033438DOI Listing
April 2005
5 Reads
3 Citations
3.540 Impact Factor

N-methyl-D-aspartate and TrkB receptors protect neurons against glutamate excitotoxicity through an extracellular signal-regulated kinase pathway.

J Neurosci Res 2005 Apr;80(1):104-13

Department of Neurology and Neuroscience, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA.

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http://dx.doi.org/10.1002/jnr.20422DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855499PMC
April 2005
18 Reads
16 Citations
2.594 Impact Factor

Haplotype structure of the beta adrenergic receptor genes in US Caucasians and African Americans.

Eur J Hum Genet 2005 Mar;13(3):341-51

Pain and Neurosensory Mechanisms Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1038/sj.ejhg.5201313DOI Listing
March 2005
10 Reads
10 Citations
4.350 Impact Factor

Haplotype-based analysis of alpha 2A, 2B, and 2C adrenergic receptor genes captures information on common functional loci at each gene.

J Hum Genet 2005 8;50(1):12-20. Epub 2004 Dec 8.

Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, Department of Health and Human Services, National Institutes of Health, Bethesda, 20892, MD, USA.

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http://dx.doi.org/10.1007/s10038-004-0211-yDOI Listing
March 2005
10 Reads
7 Citations
2.462 Impact Factor

Differential expression of human COMT alleles in brain and lymphoblasts detected by RT-coupled 5' nuclease assay.

Psychopharmacology (Berl) 2004 Dec 28;177(1-2):178-84. Epub 2004 Jul 28.

Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, 12420 Parklawn Dr., Rockville, MD 20852, USA.

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http://dx.doi.org/10.1007/s00213-004-1938-zDOI Listing
December 2004
10 Reads
14 Citations
3.880 Impact Factor

Disrupted in schizophrenia 1 (DISC1): association with schizophrenia, schizoaffective disorder, and bipolar disorder.

Am J Hum Genet 2004 Nov 22;75(5):862-72. Epub 2004 Sep 22.

Section of Human Neurogenetics and Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, Rockville, MD, USA.

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http://dx.doi.org/10.1086/425586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1182115PMC
November 2004
1 Read
98 Citations
10.931 Impact Factor

Haplotype architecture of the norepinephrine transporter gene SLC6A2 in four populations.

J Hum Genet 2004 ;49(5):232-45

Pain and Neurosensory Mechanisms Branch, National Institute of Dental and Craniofacial Research, Bethesda, MD, USA.

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http://dx.doi.org/10.1007/s10038-004-0140-9DOI Listing
October 2004
6 Reads
2 Citations
2.462 Impact Factor

Role of brain-derived neurotrophic factor and NF-kappaB in neuronal plasticity and survival: From genes to phenotype.

Restor Neurol Neurosci 2004 ;22(2):121-30

Department of Neurology, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.

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September 2004
13 Reads
33 Citations
2.490 Impact Factor

AMPA protects cultured neurons against glutamate excitotoxicity through a phosphatidylinositol 3-kinase-dependent activation in extracellular signal-regulated kinase to upregulate BDNF gene expression.

J Neurochem 2004 Aug;90(4):807-18

Department of Neurology and Neuroscience, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2004.02526.xDOI Listing
August 2004
10 Reads
16 Citations
4.281 Impact Factor

Association of specific haplotypes of D2 dopamine receptor gene with vulnerability to heroin dependence in 2 distinct populations.

Arch Gen Psychiatry 2004 Jun;61(6):597-606

Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, Rockville, MD, USA.

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http://dx.doi.org/10.1001/archpsyc.61.6.597DOI Listing
June 2004
16 Reads
37 Citations
14.480 Impact Factor

Sites in the fourth membrane-associated domain regulate alcohol sensitivity of the NMDA receptor.

Neuropharmacology 2004 Apr;46(5):647-54

Unit on Cellular Neuropharmacology, Laboratory of Molecular and Cellular Neurobiology and Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892-8115, USA.

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http://dx.doi.org/10.1016/j.neuropharm.2003.11.006DOI Listing
April 2004
2 Reads
19 Citations
5.110 Impact Factor

Genomics and variation of ionotropic glutamate receptors.

Ann N Y Acad Sci 2003 Nov;1003:22-35

Laboratory of Neurogenetics, National Institute on Alcoholism and Alcohol Abuse, National Institutes of Health, Rockville, Maryland 20852, USA.

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http://dx.doi.org/10.1196/annals.1300.003DOI Listing
November 2003
8 Citations
4.313 Impact Factor

N-methyl-D-aspartate and TrkB receptor activation in cerebellar granule cells: an in vitro model of preconditioning to stimulate intrinsic survival pathways in neurons.

Ann N Y Acad Sci 2003 May;993:134-45; discussion 159-60

Department of Neurology and Neuroscience, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2597300PMC
http://dx.doi.org/10.1111/j.1749-6632.2003.tb07522.xDOI Listing
May 2003
11 Reads
15 Citations
4.313 Impact Factor

A site in the fourth membrane-associated domain of the N-methyl-D-aspartate receptor regulates desensitization and ion channel gating.

J Biol Chem 2003 Jan 31;278(1):276-83. Epub 2002 Oct 31.

Unit on Cellular Neuropharmacology, Laboratory of Molecular and Cellular Neurobiology, National Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland 20892-8115, USA.

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http://dx.doi.org/10.1074/jbc.M209486200DOI Listing
January 2003
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25 Citations
4.573 Impact Factor

Single-nucleotide polymorphism allele frequencies determined by quantitative kinetic assay of pooled DNA.

Clin Chem 2002 Sep;48(9):1605-8

Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism/NIH, 12420 Parklawn Drive, Park 5 Building, Room 451, MSC 8110, Rockville, MD 20852, USA.

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September 2002
2 Reads
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