Robert Landsiedel, PD Dr. rer. nat. , ERT, DABT, FellowATS - BASF SE, Experimental Toxicology and Ecology - VP

Robert Landsiedel

PD Dr. rer. nat. , ERT, DABT, FellowATS

BASF SE, Experimental Toxicology and Ecology

VP

Ludwigshafen am Rhein | Germany

Main Specialties: Chemistry, Pharmacology

Additional Specialties: Toxicology

ORCID logohttps://orcid.org/0000-0003-3756-1904

Robert Landsiedel, PD Dr. rer. nat. , ERT, DABT, FellowATS - BASF SE, Experimental Toxicology and Ecology - VP

Robert Landsiedel

PD Dr. rer. nat. , ERT, DABT, FellowATS

Introduction

Dr. Robert Landsiedel earned a Ph.D. (Dr. rer. nat.) in chemistry and a postgraduate degree in toxicology. After a postdoc position at the toxicology department of the German institute of human nutrition in Potsdam, he started working for BASF in Ludwigshafen am Rhein, Germany, in 1999. After assignments in product development and product safety in North Carolina, USA and Tokyo, Japan, he returned to Ludwigshafen in 2006.
He is now Vice President of an experimental toxicology unit. His team is performing more than 500 toxicological studies per year for regulatory and screening purposes according to Good Laboratory Practice (GLP), Good In Vitro Method Practice (GIVIMP) and ISO 17020. Moreover, they are developing new methods in toxicology and performing research on the safety of new materials (nanomaterials). His team has participated in more than 10 publicly-funded research projects and published more than 100 highly-cited (>10 citations) scientific papers.
In 2012 they received the BASF Innovation Award and in 2013 the Research Award of the state of Rhineland-Palatinate as well as the German Federal Research Award for the development of alternative methods; in 2016 Robert received the German Toxicology Award and in 2018 his team received the European Responsible Care Award by the European Chemical Industry Council(Cefic).
He is Vice-chairman of the German Society of Toxicology and member of the Scientific Committee on Occupational Exposure Limits (SCOEL) of the EU Commission; he is lecturer (Privatdozent) in toxicology at the Free University of Berlin (FU Berlin) and the Medical school of the University of Leipzig.

Primary Affiliation: BASF SE, Experimental Toxicology and Ecology - Ludwigshafen am Rhein , Germany

Specialties:

Additional Specialties:

Research Interests:

Metrics

Number of Publications

102

Publications

Number of Profile Views

456

Profile Views

Number of Article Reads

1718

Reads

Number of Citations

1001

Citations

Education

Jan 2013 - May 2017
Free University of Berlin
Habilitation, Privatdozent
Aug 1994 - Dec 1997
Johannes Gutenberg University of Mainz, University of Kaiserslautern
Dr. rer. nat.
Jan 1994 - Jan 1996
University of Leipzig
Fachchemiker für Toxikologie (Postgraduate Degree)

Experience

Jan 2016
BASF SE
Vice President
Mar 2014
European Commission
member
Jan 2008
German Toxicology Society
Co chair
Jan 2006 - Jan 2006
BASF SE
Senior research manager
Sep 2004 - May 2004
BASF Agro Japan
Manager
Jan 2002 - Jan 2002
BASF Corporation
Senior Scientist
Jan 1999 - Jan 1999
BASF Aktiengesellschaft
Scientist
Dec 1997 - Aug 1994
German Institute of Human Nutrition (DIfE)
PostDoc
Jul 1993
Environmental Ministry of Rhineland-Palatinate
charted chemist (Staatsexamen Lebensmittelchemie)

Top co-authors

Lan Ma-Hock
Lan Ma-Hock

Universität Ulm

29
Wendel Wohlleben
Wendel Wohlleben

Institute of Advanced Materials and Processes (ZMP)

24
Karin Wiench
Karin Wiench

Institute for Health and Consumer Protection

22
Ursula G Sauer
Ursula G Sauer

Institute for Health and Consumer Protection

15
Volker Strauss
Volker Strauss

Pathology and Clinical Pathology

15
Annette Mehling
Annette Mehling

University of Münster

12
Eric Fabian
Eric Fabian

BASF SE

11
Silke Treumann
Silke Treumann

University of Cologne

10

Publications

102Publications

1718Reads

1001PubMed Central Citations

Correction to: Xenobiotica-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin models.

Arch Toxicol 2018 Sep 12. Epub 2018 Sep 12.

Experimental Toxicology and Ecology, GV/TB, Z470, BASF SE, Carl-Bosch-Str. 38, 67056, Ludwigshafen, Germany.

View Article
September 2018
5.980 Impact Factor

Xenobiotica-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin models.

Arch Toxicol 2018 Aug 18;92(8):2411-2456. Epub 2018 Jun 18.

Experimental Toxicology and Ecology, GV/TB, Z470, BASF SE, Carl-Bosch-Str. 38, 67056, Ludwigshafen, Germany.

View Article
August 2018
14 Reads
5.980 Impact Factor

In Vitro and In Vivo Short-Term Pulmonary Toxicity of Differently Sized Colloidal Amorphous SiO₂.

Nanomaterials (Basel) 2018 Mar 13;8(3). Epub 2018 Mar 13.

BASF SE, Experimental Toxicology and Ecology, 67056 Ludwigshafen, Germany.

View Article
March 2018
2 Reads
1 Citation

A multi-laboratory evaluation of microelectrode array-based measurements of neural network activity for acute neurotoxicity testing.

Neurotoxicology 2017 May 29;60:280-292. Epub 2016 Mar 29.

National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, NC, USA. Electronic address:

View Article
May 2017
35 Reads
5 Citations
3.380 Impact Factor

A protocol to determine dermal absorption of xenobiotica through human skin in vitro.

Arch Toxicol 2017 Mar 5;91(3):1497-1511. Epub 2016 Jul 5.

Experimental Toxicology and Ecology, BASF SE, 67056, Ludwigshafen am Rhein, Germany.

View Article
March 2017
26 Reads
5.980 Impact Factor

Assessment of the oxidative potential of nanoparticles by the cytochrome c assay: assay improvement and development of a high-throughput method to predict the toxicity of nanoparticles.

Arch Toxicol 2017 Jan 8;91(1):163-177. Epub 2016 Apr 8.

Unit of Functional and Adaptive Biology (BFA), Lab of Molecular and Cellular Responses to Xenobiotics, UMR CNRS 8251, Univ-Paris-Diderot (Sorbonne Paris Cité), 5 rue Thomas Mann, 75205, Paris Cedex 13, France.

View Article
January 2017
13 Reads
1 Citation
5.980 Impact Factor

No genotoxicity in rat blood cells upon 3- or 6-month inhalation exposure to CeO2 or BaSO4 nanomaterials.

Mutagenesis 2017 01 9;32(1):13-22. Epub 2016 Feb 9.

Experimental Toxicology and Ecology, BASF SE, 67056 Ludwigshafen, Germany.

View Article
January 2017
2 Reads
4 Citations
2.790 Impact Factor

Concern-driven integrated approaches for the grouping, testing and assessment of nanomaterials.

Environ Pollut 2016 Nov 14;218:1376-1380. Epub 2015 Nov 14.

BASF SE, Experimental Toxicology and Ecology, Ludwigshafen am Rhein, Germany. Electronic address:

View Article
November 2016
11 Reads
2 Citations
4.140 Impact Factor

The way forward for risk assessment of nanomaterials in solid media.

Environ Pollut 2016 Nov 14;218:1363-1364. Epub 2015 Dec 14.

ARCHE (Assessing Risks of CHEmicals), Stapelplein 70 box 104, 9000 Gent, Belgium.

View Article
November 2016
7 Reads
2 Citations
4.140 Impact Factor

Acute oral toxicity testing: Scientific evidence and practicability should govern Three Rs activities.

Altern Lab Anim 2016 Sep;44(4):391-398

BASF SE, Experimental Toxicology and Ecology, Ludwigshafen, Germany.

View Article
September 2016
8 Reads
1.590 Impact Factor

Local tolerance testing under REACH: Accepted non-animal methods are not on equal footing with animal tests.

Altern Lab Anim 2016 Jul;44(3):281-99

BASF SE, Experimental Toxicology and Ecology, Ludwigshafen, Germany.

View Article
July 2016
60 Reads
1.590 Impact Factor

Evaluation of non-animal methods for assessing skin sensitisation hazard: A Bayesian Value-of-Information analysis.

Altern Lab Anim 2016 Jul;44(3):255-69

BASF SE, Experimental Toxicology and Ecology, Ludwigshafen, Germany.

View Article
July 2016
40 Reads
1.590 Impact Factor

Activities of xenobiotic metabolizing enzymes in rat placenta and liver in vitro.

Toxicol In Vitro 2016 Jun 2;33:174-9. Epub 2016 Mar 2.

BASF SE, Experimental Toxicology and Ecology, GV/TB-/470, 67056 Ludwigshafen am Rhein, Germany; Division of Toxicology, Wageningen University, Tuinlaan 5, 6700 HE Wageningen, The Netherlands. Electronic address:

View Article
June 2016
14 Reads
2.900 Impact Factor

Assessment of Pre- and Pro-haptens Using Nonanimal Test Methods for Skin Sensitization.

Chem Res Toxicol 2016 05 29;29(5):901-13. Epub 2016 Apr 29.

Experimental Toxicology and Ecology, BASF SE , Ludwigshafen, Germany.

View Article
May 2016
27 Reads
1 Citation
3.530 Impact Factor

Eye irritation testing of nanomaterials using the EpiOcular™ eye irritation test and the bovine corneal opacity and permeability assay.

Part Fibre Toxicol 2016 Apr 15;13:18. Epub 2016 Apr 15.

BASF SE, Experimental Toxicology and Ecology, GB/TB - Z470, 67056, Ludwigshafen, Germany.

View Article
April 2016
45 Reads
3 Citations
7.110 Impact Factor

An in vitro alveolar macrophage assay for predicting the short-term inhalation toxicity of nanomaterials.

J Nanobiotechnology 2016 Mar 5;14:16. Epub 2016 Mar 5.

BASF SE, Experimental Toxicology and Ecology, GB/TB - Z470, 67056, Ludwigshafen, Germany.

View Article
March 2016
15 Reads
12 Citations
4.080 Impact Factor

Read-across for hazard assessment: the ugly duckling is growing up.

Altern Lab Anim 2015 Dec;43(6):P67-71

BASF SE, Experimental Toxicology and Ecology, Ludwigshafen am Rhein, Germany.

View Article
December 2015
8 Reads
1 Citation
1.590 Impact Factor

In vitro and in vivo genotoxicity investigations of differently sized amorphous SiO2 nanomaterials.

Mutat Res Genet Toxicol Environ Mutagen 2015 Dec 31;794:57-74. Epub 2015 Oct 31.

Experimental Toxicology and Ecology, BASF SE, Ludwigshafen, Germany. Electronic address:

View Article
December 2015
15 Reads
9 Citations
2.420 Impact Factor

Oral two-generation reproduction toxicity study with NM-200 synthetic amorphous silica in Wistar rats.

Reprod Toxicol 2015 Aug 25;56:147-54. Epub 2015 Mar 25.

TNO, P.O. Box 360, 3700 AJ Zeist, The Netherlands.

View Article
August 2015
6 Reads
3 Citations
3.230 Impact Factor

P2X7R activation drives distinct IL-1 responses in dendritic cells compared to macrophages.

Cytokine 2015 Aug 9;74(2):293-304. Epub 2015 Jun 9.

Faculty of Life Sciences, Smith Building, The University of Manchester, UK. Electronic address:

View Article
August 2015
12 Reads
5 Citations
2.660 Impact Factor

Prenatal toxicity of synthetic amorphous silica nanomaterial in rats.

Reprod Toxicol 2015 Aug 18;56:141-6. Epub 2015 Apr 18.

BASF SE, Experimental Toxicology and Ecology, 67056 Ludwigshafen, Germany.

View Article
August 2015
3 Reads
4 Citations
3.230 Impact Factor

Immunophenotyping does not improve predictivity of the local lymph node assay in mice.

J Appl Toxicol 2015 Apr 3;35(4):434-45. Epub 2014 Sep 3.

BASF SE, Experimental Toxicology and Ecology, Z470, 67056, Ludwigshafen, Germany.

View Article
April 2015
17 Reads
2.980 Impact Factor

A short-term inhalation study protocol: designed for testing of toxicity and fate of nanomaterials.

Methods Mol Biol 2014 ;1199:207-12

Experimental Toxicology and Ecology, BASF SE, Ludwigshafen, Germany.

View Article
March 2015
10 Reads

A decision-making framework for the grouping and testing of nanomaterials (DF4nanoGrouping).

Regul Toxicol Pharmacol 2015 Mar 26;71(2 Suppl):S1-27. Epub 2015 Mar 26.

BASF SE, Ludwigshafen, Germany. Electronic address:

View Article
March 2015
22 Reads
25 Citations
2.030 Impact Factor

Assessing skin sensitization hazard in mice and men using non-animal test methods.

Regul Toxicol Pharmacol 2015 Mar 23;71(2):337-51. Epub 2014 Dec 23.

Safety Science Research Laboratories, Kao Corporation, 2606 Akabane, Ichikai, Haga, Tochigi 321-349, Japan.

View Article
March 2015
20 Reads
13 Citations
2.030 Impact Factor

Influence of dispersive agent on nanomaterial agglomeration and implications for biological effects in vivo or in vitro.

Toxicol In Vitro 2015 Feb;29(1):182-6

Scientific Consultancy – Animal Welfare, Neubiberg, Germany.

View Article
February 2015
7 Reads
4 Citations
2.900 Impact Factor

Suitability of skin integrity tests for dermal absorption studies in vitro.

Toxicol In Vitro 2015 Feb 2;29(1):113-23. Epub 2014 Oct 2.

BASF SE, Experimental Toxicology and Ecology, Carl-Bosch-Str. 38, 67056 Ludwigshafen, Germany. Electronic address:

View Article
February 2015
4 Reads
4 Citations
2.900 Impact Factor

Surface modifications of silica nanoparticles are crucial for their inert versus proinflammatory and immunomodulatory properties.

Int J Nanomedicine 2014 5;9:2815-32. Epub 2014 Jun 5.

Center of Allergy and Environment (ZAUM), Technische Universität and Helmholtz Zentrum München, Member of the German Center for Lung Research (DZL), Munich, Germany.

View Article
December 2014
9 Reads
14 Citations

LuSens: a keratinocyte based ARE reporter gene assay for use in integrated testing strategies for skin sensitization hazard identification.

Toxicol In Vitro 2014 Dec 27;28(8):1482-97. Epub 2014 Aug 27.

BASF SE, Experimental Toxicology and Ecology, Germany. Electronic address:

View Article
December 2014
69 Reads
6 Citations
2.900 Impact Factor

A critical appraisal of existing concepts for the grouping of nanomaterials.

Regul Toxicol Pharmacol 2014 Nov 7;70(2):492-506. Epub 2014 Aug 7.

BASF SE, Ludwigshafen, Germany. Electronic address:

View Article
November 2014
27 Reads
17 Citations
2.030 Impact Factor

Time course of lung retention and toxicity of inhaled particles: short-term exposure to nano-Ceria.

Arch Toxicol 2014 Nov 2;88(11):2033-59. Epub 2014 Oct 2.

Experimental Toxicology and Ecology, BASF SE, 67056, Ludwigshafen am Rhein, Germany.

View Article
November 2014
22 Reads
17 Citations
5.980 Impact Factor

Biokinetics and effects of barium sulfate nanoparticles.

Part Fibre Toxicol 2014 Oct 21;11:55. Epub 2014 Oct 21.

Department of Environmental Health, Molecular and Integrative Physiological Sciences Program, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA, 02115, USA.

View Article
October 2014
5 Reads
13 Citations
7.110 Impact Factor

Effects of SiO₂, ZrO₂, and BaSO₄ nanomaterials with or without surface functionalization upon 28-day oral exposure to rats.

Arch Toxicol 2014 Oct 28;88(10):1881-906. Epub 2014 Aug 28.

Experimental Toxicology and Ecology, BASF SE, 67056, Ludwigshafen am Rhein, Germany.

View Article
October 2014
9 Reads
6 Citations
5.980 Impact Factor

Automatic sorting of toxicological information into the IUCLID (International Uniform Chemical Information Database) endpoint-categories making use of the semantic search engine Go3R.

Toxicol In Vitro 2014 Jun 2;28(4):571-87. Epub 2014 Jan 2.

BASF SE, Product Safety - Experimental Toxicology and Ecology, Ludwigshafen, Germany. Electronic address:

View Article
June 2014
16 Reads
4 Citations
2.900 Impact Factor

Application of short-term inhalation studies to assess the inhalation toxicity of nanomaterials.

Part Fibre Toxicol 2014 Apr 4;11:16. Epub 2014 Apr 4.

Experimental Toxicology and Ecology, BASF SE, 67056 Ludwigshafen, Germany.

View Article
April 2014
12 Reads
23 Citations
7.110 Impact Factor

Computer models versus reality: how well do in silico models currently predict the sensitization potential of a substance.

Regul Toxicol Pharmacol 2013 Dec 30;67(3):468-85. Epub 2013 Sep 30.

BASF Schweiz AG, Basel, Switzerland. Electronic address:

View Article
December 2013
14 Reads
5 Citations
2.030 Impact Factor

Predictive toxicology of cobalt ferrite nanoparticles: comparative in-vitro study of different cellular models using methods of knowledge discovery from data.

Part Fibre Toxicol 2013 Jul 29;10:32. Epub 2013 Jul 29.

Department of Physiology and Pharmacology, Faculty of Medicine and the Marian Gertner Institute for Medical Nanosystems, Tel Aviv University, Tel-Aviv 69978, Israel.

View Article
July 2013
18 Reads
12 Citations
7.110 Impact Factor

Additional histopathologic examination of the lungs from a 3-month inhalation toxicity study with multiwall carbon nanotubes in rats.

Toxicol Sci 2013 Jul 9;134(1):103-10. Epub 2013 Apr 9.

Experimental Toxicology and Ecology, BASF SE, Ludwigshafen, Germany.

View Article
July 2013
8 Reads
8 Citations

Esterase activity in excised and reconstructed human skin--biotransformation of prednicarbate and the model dye fluorescein diacetate.

Eur J Pharm Biopharm 2013 Jun 29;84(2):374-85. Epub 2012 Nov 29.

Institut für Pharmazie (Pharmakologie und Toxikologie), Freie Universität Berlin (FU), Berlin, Germany.

View Article
June 2013
65 Reads
5 Citations
3.380 Impact Factor

Relevance of xenobiotic enzymes in human skin in vitro models to activate pro-sensitizers.

J Immunotoxicol 2012 Oct-Dec;9(4):426-38. Epub 2012 Apr 3.

BASF SE, Experimental Toxicology and Ecology, 67056 Ludwigshafen, Germany.

View Article
May 2013
2 Reads
3 Citations
1.910 Impact Factor

Performance standards and alternative assays: practical insights from skin sensitization.

Regul Toxicol Pharmacol 2013 Mar 29;65(2):278-85. Epub 2012 Dec 29.

BASF SE, Experimental Toxicology and Ecology, Ludwigshafen, Germany.

View Article
March 2013
3 Reads
3 Citations
2.030 Impact Factor

In vivo-in vitro comparison of acute respiratory tract toxicity using human 3D airway epithelial models and human A549 and murine 3T3 monolayer cell systems.

Toxicol In Vitro 2013 Feb 22;27(1):174-90. Epub 2012 Oct 22.

Scientific Consultancy - Animal Welfare, Neubiberg, Germany.

View Article
February 2013
11 Reads
10 Citations
2.900 Impact Factor

Elastic CNT-polyurethane nanocomposite: synthesis, performance and assessment of fragments released during use.

Nanoscale 2013 Jan 21;5(1):369-80. Epub 2012 Nov 21.

BASF SE, Material Physics, GMC, 67056 Ludwigshafen, Germany.

View Article
January 2013
20 Reads
14 Citations
7.390 Impact Factor

Inhalation studies for the safety assessment of nanomaterials: status quo and the way forward.

Wiley Interdiscip Rev Nanomed Nanobiotechnol 2012 Jul-Aug;4(4):399-413. Epub 2012 May 25.

BASF Experimental Toxicology and Ecology, Ludwigshafen, Germany.

View Article
January 2013
4 Reads
6 Citations

Applicability of in vitro tests for skin irritation and corrosion to regulatory classification schemes: substantiating test strategies with data from routine studies.

Regul Toxicol Pharmacol 2012 Dec 30;64(3):402-14. Epub 2012 Aug 30.

BASF SE, Experimental Toxicology and Ecology, Carl-Bosch-Straße 38, 67056 Ludwigshafen, Germany.

View Article
December 2012
6 Reads
2.030 Impact Factor

Further experience with the local lymph node assay using standard radioactive and nonradioactive cell count measurements.

J Appl Toxicol 2012 Aug 25;32(8):597-607. Epub 2012 May 25.

BASF SE, Experimental Toxicology and Ecology, Ludwigshafen, Germany.

View Article
August 2012
15 Reads
2.980 Impact Factor

Non-animal test methods for predicting skin sensitization potentials.

Arch Toxicol 2012 Aug 16;86(8):1273-95. Epub 2012 Jun 16.

BASF Personal Care and Nutrition GmbH, Düsseldorf, Germany.

View Article
August 2012
20 Reads
13 Citations
5.980 Impact Factor

Putting the parts together: combining in vitro methods to test for skin sensitizing potentials.

Regul Toxicol Pharmacol 2012 Aug 1;63(3):489-504. Epub 2012 Jun 1.

BASF SE, Experimental Toxicology and Ecology, Ludwigshafen, Germany.

View Article
August 2012
28 Reads
14 Citations
2.030 Impact Factor

Toxico-/biokinetics of nanomaterials.

Arch Toxicol 2012 Jul 11;86(7):1021-60. Epub 2012 May 11.

Department of Experimental Toxicology and Ecology, BASF SE, Ludwigshafen, Germany.

View Article
July 2012
11 Reads
24 Citations
5.980 Impact Factor

Genotoxicity investigations on nanomaterials.

Arch Toxicol 2012 Jul 29;86(7):985-94. Epub 2012 Mar 29.

Institute of Toxicology, University of Mainz, Mainz, Germany.

View Article
July 2012
3 Reads
6 Citations
5.980 Impact Factor

Hazard identification of inhaled nanomaterials: making use of short-term inhalation studies.

Arch Toxicol 2012 Jul 25;86(7):1137-51. Epub 2012 Apr 25.

European Commission, Joint Research Centre, Institute for Health and Consumer Protection, Ispra, Italy.

View Article
July 2012
16 Reads
15 Citations
5.980 Impact Factor

Nanostructured calcium silicate hydrate seeds accelerate concrete hardening: a combined assessment of benefits and risks.

Arch Toxicol 2012 Jul 31;86(7):1077-87. Epub 2012 Mar 31.

BASF Construction Chemicals GmbH, Polymer Research, Mineralogy, Trostberg, Germany.

View Article
July 2012
8 Reads
2 Citations
5.980 Impact Factor

Short-term rat inhalation study with aerosols of acrylic ester-based polymer dispersions containing a fraction of nanoparticles.

Int J Toxicol 2012 Jan-Feb;31(1):46-57. Epub 2012 Jan 19.

Experimental Toxicology and Ecology, BASF SE, Ludwigshafen, Germany.

View Article
June 2012
1 Read
3 Citations
1.230 Impact Factor

Investigation on the genotoxicity of different sizes of gold nanoparticles administered to the lungs of rats.

Mutat Res 2012 Jun 7;745(1-2):51-7. Epub 2011 Dec 7.

Experimental Toxicology and Ecology, BASF SE, 67056 Ludwigshafen, Germany.

View Article
June 2012
6 Reads
8 Citations
3.680 Impact Factor

Intralaboratory validation of four in vitro assays for the prediction of the skin sensitizing potential of chemicals.

Toxicol In Vitro 2011 Sep 7;25(6):1162-8. Epub 2011 Jun 7.

BASF SE, Experimental Toxicology and Ecology, Germany.

View Article
September 2011
14 Reads
7 Citations
2.900 Impact Factor

Assessment of combinations of antiandrogenic compounds vinclozolin and flutamide in a yeast based reporter assay.

Regul Toxicol Pharmacol 2011 Aug 18;60(3):373-80. Epub 2011 May 18.

BASF SE, Experimental Toxicology and Ecology, Ludwigshafen, Germany.

View Article
August 2011
4 Reads
2.030 Impact Factor

On the lifecycle of nanocomposites: comparing released fragments and their in-vivo hazards from three release mechanisms and four nanocomposites.

Small 2011 Aug 14;7(16):2384-95. Epub 2011 Jun 14.

Experimental Toxicology GV/T, BASF SE 67056 Ludwigshafen, Germany; Polymer Physics GKC, BASF SE 67056 Ludwigshafen, Germany.

View Article
August 2011
23 Reads
20 Citations
8.370 Impact Factor

Refinement and reduction of acute oral toxicity testing: a critical review of the use of cytotoxicity data.

Altern Lab Anim 2011 Jul;39(3):273-95

BASF SE, Experimental Toxicology and Ecology, Ludwigshafen, Germany.

View Article
July 2011
23 Reads
2 Citations
1.590 Impact Factor

Linking energy metabolism to dysfunctions in mitochondrial respiration--a metabolomics in vitro approach.

Toxicol Lett 2011 Jun 23;203(3):200-9. Epub 2011 Mar 23.

Metanomics GmbH, Berlin, Germany.

View Article
June 2011
12 Citations
3.260 Impact Factor

Chemical toxicity testing in vitro using cytochrome P450-expressing cell lines, such as human CYP1B1.

Nat Protoc 2011 May 28;6(5):677-87. Epub 2011 Apr 28.

Department of Nutritional Toxicology, German Institute of Human Nutrition (DIfE), Nuthetal, Germany.

View Article
May 2011
4 Reads
1 Citation

Gene toxicity studies on titanium dioxide and zinc oxide nanomaterials used for UV-protection in cosmetic formulations.

Nanotoxicology 2010 Dec;4:364-81

Experimental Toxicology and Ecology, BASF SE, Ludwigshafen, Germany.

View Article
December 2010
11 Reads
10 Citations
6.410 Impact Factor

Testing metal-oxide nanomaterials for human safety.

Adv Mater 2010 Jun;22(24):2601-27

BASF SE 67056 Ludwigshafen, Germany.

View Article
June 2010
3 Reads
48 Citations
17.490 Impact Factor

Experience with the HET-CAM method in the routine testing of a broad variety of chemicals and formulations.

Altern Lab Anim 2010 Mar;38(1):39-52

BASF SE, Experimental Toxicology and Ecology, Ludwigshafen, Germany.

View Article
March 2010
7 Reads
1.590 Impact Factor

Inhalation toxicity of multiwall carbon nanotubes in rats exposed for 3 months.

Toxicol Sci 2009 Dec 7;112(2):468-81. Epub 2009 Jul 7.

Product Safety, BASF SE, 67056 Ludwigshafen, Germany.

View Article
December 2009
10 Reads
88 Citations

Acute and chronic effects of nano- and non-nano-scale TiO(2) and ZnO particles on mobility and reproduction of the freshwater invertebrate Daphnia magna.

Chemosphere 2009 Sep 5;76(10):1356-65. Epub 2009 Jul 5.

BASF, Product Safety--Regulations, Toxicology and Ecology, GUP/CB-Z470, Ludwigshafen, Germany.

View Article
September 2009
13 Reads
20 Citations
3.340 Impact Factor

Comparing fate and effects of three particles of different surface properties: nano-TiO(2), pigmentary TiO(2) and quartz.

Toxicol Lett 2009 May 7;186(3):152-9. Epub 2008 Dec 7.

BASF Product Safety, BASF SE, GV/T - Z470, D-67056 Ludwigshafen, Germany.

View Article
May 2009
10 Reads
22 Citations
3.260 Impact Factor

Genotoxicity investigations on nanomaterials: methods, preparation and characterization of test material, potential artifacts and limitations--many questions, some answers.

Mutat Res 2009 Mar-Jun;681(2-3):241-58. Epub 2008 Nov 11.

Department of Product Safety, BASF SE, 67056 Ludwigshafen, Germany.

View Article
April 2009
5 Reads
34 Citations
3.680 Impact Factor

Development of a short-term inhalation test in the rat using nano-titanium dioxide as a model substance.

Inhal Toxicol 2009 Feb;21(2):102-18

Department of Product Safety, BASF SE, Ludwigshafen, Germany.

View Article
February 2009
8 Reads
31 Citations
2.260 Impact Factor

Tissue distribution and toxicity of intravenously administered titanium dioxide nanoparticles in rats.

Arch Toxicol 2008 Mar 14;82(3):151-7. Epub 2007 Nov 14.

BASF Product Safety, BASF Aktiengesellschaft, Ludwigshafen, Germany.

View Article
March 2008
6 Reads
38 Citations
5.980 Impact Factor

Drug-metabolizing enzymes in the skin of man, rat, and pig.

Drug Metab Rev 2007 ;39(4):659-98

Institute of Toxicology, University of Mainz, Mainz, Germany.

View Article
December 2007
15 Reads
15 Citations
5.360 Impact Factor

Top co-authors

Lan Ma-Hock
Lan Ma-Hock

Universität Ulm

29
Wendel Wohlleben
Wendel Wohlleben

Institute of Advanced Materials and Processes (ZMP)

24
Karin Wiench
Karin Wiench

Institute for Health and Consumer Protection

22
Ursula G Sauer
Ursula G Sauer

Institute for Health and Consumer Protection

15
Volker Strauss
Volker Strauss

Pathology and Clinical Pathology

15
Annette Mehling
Annette Mehling

University of Münster

12
Eric Fabian
Eric Fabian

BASF SE

11
Silke Treumann
Silke Treumann

University of Cologne

10