Robert L Walker

Robert L Walker

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Robert L Walker

Robert L Walker

Publications by authors named "Robert L Walker"

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HNRNPH1-dependent splicing of a fusion oncogene reveals a targetable RNA G-quadruplex interaction.

RNA 2019 Sep 11. Epub 2019 Sep 11.

Functional Genetics Section, Genetics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA;

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http://dx.doi.org/10.1261/rna.072454.119DOI Listing
September 2019

Engineered Bcor mutations lead to acute leukemia of progenitor B-1 lymphocyte origin in a sensitized background.

Blood 2019 Jun 16;133(24):2610-2614. Epub 2019 Apr 16.

Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD; and.

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http://dx.doi.org/10.1182/blood.2018864173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566592PMC
June 2019

Rapid and reversible suppression of ALT by DAXX in osteosarcoma cells.

Sci Rep 2019 Mar 14;9(1):4544. Epub 2019 Mar 14.

Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.

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http://www.nature.com/articles/s41598-019-41058-8
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http://dx.doi.org/10.1038/s41598-019-41058-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418139PMC
March 2019

Structural features of α-synuclein amyloid fibrils revealed by Raman spectroscopy.

J Biol Chem 2018 01 30;293(3):767-776. Epub 2017 Nov 30.

From the Laboratory of Protein Conformation and Dynamics, Biochemistry and Biophysics Center, NHLBI, National Institutes of Health, Bethesda, Maryland 20892

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http://dx.doi.org/10.1074/jbc.M117.812388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777252PMC
January 2018

Somatic mutations in murine models of leukemia and lymphoma: Disease specificity and clinical relevance.

Genes Chromosomes Cancer 2017 Jun 31;56(6):472-483. Epub 2017 Mar 31.

Genetics Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland.

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http://dx.doi.org/10.1002/gcc.22451DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399546PMC
June 2017

Point Mutations in Exon 1B of APC Reveal Gastric Adenocarcinoma and Proximal Polyposis of the Stomach as a Familial Adenomatous Polyposis Variant.

Am J Hum Genet 2016 05 14;98(5):830-842. Epub 2016 Apr 14.

Department of Genetics and Computational Biology, QIMR Berghofer, Herston, QLD 4029, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2016.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863475PMC
May 2016

Tryptophan probes reveal residue-specific phospholipid interactions of apolipoprotein C-III.

Biochim Biophys Acta 2015 Nov 22;1848(11 Pt A):2821-8. Epub 2015 Aug 22.

Laboratory of Molecular Biophysics, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbamem.2015.08.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598292PMC
November 2015

NUP98-PHF23 is a chromatin-modifying oncoprotein that causes a wide array of leukemias sensitive to inhibition of PHD histone reader function.

Cancer Discov 2014 May 17;4(5):564-77. Epub 2014 Feb 17.

1Genetics Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda; 2Department of Pathology, Johns Hopkins University, Baltimore, Maryland; 3Department of Biomolecular Chemistry, University of Wisconsin, Madison, Wisconsin; and 4Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina.

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http://dx.doi.org/10.1158/2159-8290.CD-13-0419DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018760PMC
May 2014

High prevalence of MAP2K1 mutations in variant and IGHV4-34-expressing hairy-cell leukemias.

Nat Genet 2014 Jan 17;46(1):8-10. Epub 2013 Nov 17.

Genetics Branch, Center for Cancer Research (CCR), National Cancer Institute (NCI), US National Institutes of Health (NIH), Bethesda, Maryland, USA.

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http://dx.doi.org/10.1038/ng.2828DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905739PMC
January 2014

Prohibitin expression is associated with high grade breast cancer but is not a driver of amplification at 17q21.33.

Pathology 2013 12;45(7):629-36

*Sydney Medical School - Westmead, University of Sydney, Westmead †Westmead Institute for Cancer Research, Westmead ‡Westmead Millennium Institute, Westmead §Tissue Pathology, Institute of Clinical Pathology and Medical Research, Westmead Hospital, Westmead ||Translational Oncology, Sydney West Cancer Network, Western Sydney and Nepean Blue Mountains Local Health Districts, Westmead ¶Anatomical Pathology, St Vincent's Hospital, Darlinghurst **Prince of Wales Clinical School, University of New South Wales, Randwick ††School of Medical Sciences University of New South Wales, Randwick ‡‡School of Biomedical Sciences, Charles Sturt University, Wagga Wagga, New South Wales, Australia §§Genetics Branch, National Cancer Institute, Bethesda MD USA ||||these authors contributed equally to this work.

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https://linkinghub.elsevier.com/retrieve/pii/S00313025163147
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http://dx.doi.org/10.1097/PAT.0000000000000004DOI Listing
December 2013

CD8(+) lymphocytes suppress human immunodeficiency virus 1 replication by secreting type I interferons.

J Interferon Cytokine Res 2013 Nov 12;33(11):632-45. Epub 2013 Feb 12.

1 Department of Medicine, University of California San Francisco , San Francisco, California.

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http://dx.doi.org/10.1089/jir.2012.0067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814821PMC
November 2013

Oncogenic ETS fusions deregulate E2F3 target genes in Ewing sarcoma and prostate cancer.

Genome Res 2013 Nov 12;23(11):1797-809. Epub 2013 Aug 12.

Genetics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892, USA;

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http://dx.doi.org/10.1101/gr.151340.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814880PMC
November 2013

Complex temporal changes in TGFβ oncogenic signaling drive thyroid carcinogenesis in a mouse model.

Carcinogenesis 2013 Oct 22;34(10):2389-400. Epub 2013 May 22.

Gene Regulation Section, Laboratory of Molecular Biology and.

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http://dx.doi.org/10.1093/carcin/bgt175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786374PMC
October 2013

The exomes of the NCI-60 panel: a genomic resource for cancer biology and systems pharmacology.

Cancer Res 2013 Jul 15;73(14):4372-82. Epub 2013 Jul 15.

Genetics Branch, Laboratory of Molecular Pharmacology, Center for Cancer Research, and Division of Cancer Treatment and Diagnosis, National Cancer Institute, NIH, Bethesda, MD 20982, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-3342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893961PMC
July 2013

Enforced expression of Lin28b leads to impaired T-cell development, release of inflammatory cytokines, and peripheral T-cell lymphoma.

Blood 2012 Aug 21;120(5):1048-59. Epub 2012 Jun 21.

Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1182/blood-2012-01-401760DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412328PMC
August 2012

Genome-wide methylation profiling in archival formalin-fixed paraffin-embedded tissue samples.

Methods Mol Biol 2012 ;823:107-18

Cancer Genetics Branch, National Institutes of Health/National Cancer Institute, Bethesda, MD, USA.

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http://dx.doi.org/10.1007/978-1-60327-216-2_8DOI Listing
April 2012

Docosahexaenoic acid pretreatment confers protection and functional improvements after acute spinal cord injury in adult rats.

J Neurotrauma 2012 Feb 7;29(3):551-66. Epub 2011 Nov 7.

Center for Health Disparities and Molecular Medicine and Department of Basic Sciences, Loma Linda University, Loma Linda, California, USA.

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http://dx.doi.org/10.1089/neu.2011.2141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278822PMC
February 2012

Genome-wide identification of PAX3-FKHR binding sites in rhabdomyosarcoma reveals candidate target genes important for development and cancer.

Cancer Res 2010 Aug 27;70(16):6497-508. Epub 2010 Jul 27.

Genetics Branch, Center for Cancer Research, National Cancer Institute, National Human Genome Research Institute, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-0582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922412PMC
August 2010

Negative regulation of TSHalpha target gene by thyroid hormone involves histone acetylation and corepressor complex dissociation.

Mol Endocrinol 2009 May 5;23(5):600-9. Epub 2009 Feb 5.

Endocrinology Division, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1210/me.2008-0389DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2675953PMC
May 2009

Thyroid hormone responsive genes in cultured human fibroblasts.

J Clin Endocrinol Metab 2005 Feb 26;90(2):936-43. Epub 2004 Oct 26.

Department of Medicine, The University of Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1210/jc.2004-1768DOI Listing
February 2005

The gene expression response of breast cancer to growth regulators: patterns and correlation with tumor expression profiles.

Cancer Res 2003 Nov;63(21):7158-66

Cancer Genetics Branch, National Human Genome Research Institute/NIH, 50 South Drive, Bethesda, MD 20892, USA.

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November 2003

Gene expression profiles in a panel of childhood leukemia cell lines mirror critical features of the disease.

Mol Cancer Ther 2003 Jul;2(7):671-7

Telethon Institute for Child Health Research, The University of Western Australia, Perth, Australia and National Human Genome Research Institute, NIH, Bethesda, Maryland 20892, USA.

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July 2003

Effects of ligand and thyroid hormone receptor isoforms on hepatic gene expression profiles of thyroid hormone receptor knockout mice.

EMBO Rep 2003 Jun;4(6):581-7

Molecular Regulation and Neuroendocrinology Section, Clinical Endocrinology Branch, National Institute of Diabetes and Digestive and Kidney Diseases/NIH, Room 8D12, Building 10, Bethesda, MD 20892, USA.

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http://embor.embopress.org/cgi/doi/10.1038/sj.embor.embor862
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http://dx.doi.org/10.1038/sj.embor.embor862DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1319202PMC
June 2003