Publications by authors named "Robert L Schmidt"

100Publications

Reliability of Total Nucleated Cell Counts in the Setting of Hip Arthroplasty.

J Appl Lab Med 2020 Nov 12. Epub 2020 Nov 12.

Department of Orthopaedics, University of Utah, Salt Lake City, UT.

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November 2020

Decreasing median age of COVID-19 cases in the United States-Changing epidemiology or changing surveillance?

PLoS One 2020 15;15(10):e0240783. Epub 2020 Oct 15.

Department of Pathology, University of Utah, Salt Lake City, Utah, United States of America.

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October 2020

The costs and benefits of cross-level quality control rules.

Clin Chim Acta 2020 Nov 8;510:697-702. Epub 2020 Sep 8.

Department of Pathology, University of Utah, Salt Lake City, UT, United States; ARUP Laboratories, Salt Lake City, UT, United States. Electronic address:

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November 2020

D-Dimer Varies Widely Across Instrument Platforms and is Not a Reliable Indicator of Periprosthetic Joint Infections.

Arthroplast Today 2020 Dec 23;6(4):686-688. Epub 2020 Aug 23.

Department of Pathology, ARUP Laboratories & University of Utah, Salt Lake City, UT, USA.

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December 2020

(1→3)-β-D-glucan testing for the detection of invasive fungal infections in immunocompromised or critically ill people.

Cochrane Database Syst Rev 2020 07 21;7:CD009833. Epub 2020 Jul 21.

Director, Transplant Infectious Diseases and Immunocompromised Host Service, Section Head, Clinical Microbiology, Director, Medical Microbiology Fellowship Program, University of Utah and ARUP Laboratories, Salt Lake City, Utah, USA.

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July 2020

Are calprotectin and lactoferrin equivalent screening tests for inflammatory bowel disease?

Clin Chim Acta 2020 Nov 14;510:191-195. Epub 2020 Jul 14.

Department of Pathology and ARUP Laboratories, University of Utah, Salt Lake City, UT, United States. Electronic address:

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November 2020

The comparative safety of bacterial risk control strategies for platelet components: a simulation study.

Transfusion 2020 Aug 6;60(8):1723-1731. Epub 2020 Jul 6.

Department of Pathology and ARUP Laboratories, University of Utah, Salt Lake City, Utah, USA.

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August 2020

When To Retest: an Examination of Repeat COVID-19 PCR Patterns in an Ambulatory Population.

J Clin Microbiol 2020 08 24;58(9). Epub 2020 Aug 24.

University of Utah, Department of Pathology, Salt Lake City, Utah, USA

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August 2020

Clinical Laboratory Employees' Attitudes Toward Artificial Intelligence.

Lab Med 2020 Nov;51(6):649-654

University of Utah Department of Pathology and ARUP Laboratories, Salt Lake City, UT.

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November 2020

Bacterial contamination rate of platelet components by primary culture: a systematic review and meta-analysis.

Transfusion 2020 05 17;60(5):986-996. Epub 2020 Mar 17.

Department of Pathology, University of Utah, Salt Lake City, Utah.

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May 2020

Cost effectiveness of therapeutic drug monitoring for imatinib administration in chronic myeloid leukemia.

PLoS One 2019 23;14(12):e0226552. Epub 2019 Dec 23.

Department of Pathology and ARUP Laboratories, University of Utah, Salt Lake City, Utah, United States of America.

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April 2020

Bad Tests Die Slowly: The Myelin Basic Protein Example.

J Appl Lab Med 2020 01;5(1):136-141

Department of Pathology and ARUP Laboratories, University of Utah, Salt Lake City, UT.

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January 2020

Pathology Assessment of Femoral Head Resection Specimens: An Important Quality Assurance Procedure.

Arch Pathol Lab Med 2020 05 20;144(5):580-585. Epub 2019 Sep 20.

From the Departments of Pathology and Anatomical Sciences (Dr Layfield) and Radiology (Dr Crim), University of Missouri, Columbia; University of Missouri School of Medicine, M2, Columbia (Mr Oserowsky); and the Department of Pathology and ARUP Laboratories, University of Utah, Salt Lake City (Dr Schmidt).

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May 2020

Dr. Tebo, reply.

J Rheumatol 2019 11 1;46(11):1547. Epub 2019 Aug 1.

Department of Rheumatology, University of Utah, Salt Lake City, Utah, USA.

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November 2019

Laboratory Evaluation of Antiphospholipid Syndrome.

Am J Clin Pathol 2019 10;152(5):638-646

ARUP Institute of Clinical and Experimental Pathology, University of Utah School of Medicine, Salt Lake City.

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October 2019

Cytomorphological criteria for separation of pulmonary adenocarcinomas from squamous cell carcinomas: A statistical learning approach.

Cytopathology 2019 11 20;30(6):601-606. Epub 2019 Aug 20.

Department of Pathology & ARUP Laboratories, University of Utah, Salt Lake City, UT, USA.

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November 2019

An Analysis of Multirules for Monitoring Assay Quality Control.

Lab Med 2020 Jan;51(1):94-98

Department of Pathology, University of Utah and ARUP Laboratories, Salt Lake City.

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January 2020

Comparison of Radiography and Histopathologic Analysis in the Evaluation of Hip Arthritis.

AJR Am J Roentgenol 2019 10 5;213(4):895-902. Epub 2019 Jun 5.

Department of Pathology, University of Utah, Salt Lake City, UT.

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October 2019

Quality control optimization part II: A method to optimize the accuracy of laboratory quality control.

Clin Chim Acta 2019 Aug 17;495:233-238. Epub 2019 Apr 17.

Department of Pathology, University of Utah, Salt Lake City, UT, United States of America. Electronic address:

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August 2019

Quality control optimization part I: Metrics for evaluating predictive performance of quality control.

Clin Chim Acta 2019 Aug 8;495:174-184. Epub 2019 Apr 8.

The Department of Pathology, University of Utah, Salt Lake City, UT, United States of America. Electronic address:

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August 2019

A Profile of Point of Care Coordinators: Roles, Responsibilities and Attitudes.

Lab Med 2019 Jul;50(3):e50-e55

Department of Pathology, University of Utah, Salt Lake City, UT.

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July 2019

Estimating the cost of quality of errors in the analytical phase.

Clin Chim Acta 2019 Aug 1;495:60-66. Epub 2019 Apr 1.

Department of Pathology, ARUP Laboratories, University of Utah, Salt Lake City, UT, United States of America. Electronic address:

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August 2019

Presence of Antitopoisomerase I Antibody Alone May Not Be Sufficient for the Diagnosis of Systemic Sclerosis.

J Rheumatol 2019 04 1;46(4):440-442. Epub 2019 Mar 1.

Department of Rheumatology, University of Utah, Salt Lake City, Utah, USA.

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April 2019

A Mechanism-Based Population Pharmacokinetics Model of Erythropoietin in Premature Infants and Healthy Adults Following Multiple Intravenous Doses.

J Clin Pharmacol 2019 06 7;59(6):835-846. Epub 2019 Jan 7.

Division of Pharmaceutics and Translational Therapeutics, College of Pharmacy, University of Iowa, Iowa City, IA, USA.

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June 2019

What Does it Mean for a Recommendation to be Evidence-Based?

Lab Med 2019 01;50(1):5-7

Department of Pathology and ARUP Laboratories, University of Utah Health Sciences Center, Salt Lake City.

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January 2019

Molecular Testing Strategies for Pulmonary Adenocarcinoma: An Optimal Approach With Cost Analysis.

Arch Pathol Lab Med 2019 05 21;143(5):628-633. Epub 2018 Dec 21.

From the Department of Pathology & Anatomical Sciences, University of Missouri, Columbia (Drs Layfield and Hammer); and the Department of Pathology and ARUP Laboratories, University of Utah, Salt Lake City (Ms White and Drs Furtado and Schmidt).

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May 2019

Is your assay stable? Using process stability and capability to evaluate assay performance.

Clin Chim Acta 2019 Mar 13;490:28-33. Epub 2018 Dec 13.

Department of Pathology and ARUP Laboratories, University of Utah, Salt Lake City, UT, United States. Electronic address:

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March 2019

Overlooked Issues on Pharmacokinetics Data Interpretation of Protein Drugs-a Case Example of Erythropoietin.

AAPS J 2018 11 26;21(1). Epub 2018 Nov 26.

Department of Pediatrics, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, USA.

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November 2018

Adoption of Evidence-Based Medicine in Clinical Laboratory Science: A Survey of the Prevalence of Systematic and Narrative Reviews.

Lab Med 2019 Jul;50(3):223-228

Department of Pathology and ARUP Laboratories, University of Utah, Salt Lake City, UT.

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July 2019

Cost-effectiveness of rapid on-site evaluation of the adequacy of FNA cytology samples performed by nonpathologists.

Cancer Cytopathol 2018 10 12;126(10):839-845. Epub 2018 Oct 12.

Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah.

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October 2018

Diagnostic Accuracy of β-d-Glucan (Fungitell) Testing Among Patients With Hematologic Malignancies or Solid Organ Tumors: A Systematic Review and Meta-Analysis.

Am J Clin Pathol 2019 02;151(3):275-285

Department of Pathology, Division of Infectious Disease, Health Sciences Center, University of Utah, Salt Lake City.

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February 2019

The Papanicolaou Society of Cytopathology guidelines for respiratory cytology: Reproducibility of categories among observers.

Cytojournal 2018 21;15:22. Epub 2018 Sep 21.

Department of Pathology and Arup Laboratories, University of Utah, Salt Lake City, UT 84112, USA.

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September 2018

Reliability and Validity of Proposed Risk Stratification Methods for Laboratory Developed Tests.

Lab Med 2019 Apr;50(2):194-201

Department of Pathology, University of Utah and ARUP Laboratories, Salt Lake City, Utah.

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April 2019

Quality control limits: Are we setting them too wide?

Clin Chim Acta 2018 Nov 23;486:329-334. Epub 2018 Aug 23.

Department of Pathology, ARUP Laboratories, University of Utah, Salt Lake City, UT, United States. Electronic address:

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November 2018

Assessment of diagnostic methods for the detection of anticardiolipin and anti-βeta glycoprotein I antibodies in patients under routine evaluation for antiphospholipid syndrome.

Clin Chim Acta 2018 Oct 5;485:7-13. Epub 2018 Jun 5.

ARUP Institute of Clinical and Experimental Pathology, Salt Lake City, UT, USA; Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT, USA. Electronic address:

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October 2018

An Audit of Repeat Testing at an Academic Medical Center: Consistency of Order Patterns With Recommendations and Potential Cost Savings.

Am J Clin Pathol 2018 May;150(1):27-33

Department of Pathology, Health Sciences Center, University of Utah, Salt Lake City.

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May 2018

Findings Associated With Knee Pathology on MRI in Patients Without Osteoarthritis.

J Am Acad Orthop Surg 2017 Nov;25(11):780-786

From the Department of Orthopaedics, Boston Children's Hospital, Boston, MA (Dr. Wylie), the Department of Orthopaedics, University of Utah, Salt Lake City, UT (Dr. Makarewich, Dr. Working, Dr. Jacobson, Dr. Schmidt, and Dr. Burks), and the Department of Radiology, University of Missouri, Columbia, MO (Dr. Crim).

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November 2017

A Survey of the Prevalence and Impact of Reporting Guideline Endorsement in Pathology Journals.

Am J Clin Pathol 2017 Oct;148(4):314-322

Department of Pathology and ARUP Laboratories, University of Utah Health Sciences Center, Salt Lake City.

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October 2017

Frozen Section Evaluation of Margin Status in Primary Squamous Cell Carcinomas of the Head and Neck: A Correlation Study of Frozen Section and Final Diagnoses.

Head Neck Pathol 2018 Jun 23;12(2):175-180. Epub 2017 Aug 23.

Department of Pathology and Anatomical Sciences, University of Missouri, One Hospital Drive, M263 Medical Sciences Building, Columbia, MO, 65212, USA.

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June 2018

Interobserver reproducibility of The Paris System for Reporting Urinary Cytology.

Cytojournal 2017 24;14:17. Epub 2017 Jul 24.

Department of Pathology and Laboratory Medicine and ARUP Laboratories, University of Utah, Salt Lake City, Utah, USA.

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July 2017

Organizational Benchmarks for Test Utilization Performance: An Example Based on Positivity Rates for Genetic Tests.

Am J Clin Pathol 2017 Apr;147(4):382-389

Center for Effective Medical Testing, Department of Pathology, University of Utah, Salt Lake City.

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April 2017

Estimation of adult and neonatal RBC lifespans in anemic neonates using RBCs labeled at several discrete biotin densities.

Pediatr Res 2017 Jun 18;81(6):905-910. Epub 2017 Jan 18.

Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, Iowa.

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June 2017

Reference pricing may have limited use but is not a blanket solution for laboratory testing.

Ann Transl Med 2016 Nov;4(21):429

Department of Pathology, University of Utah Health Sciences Center and ARUP Laboratories, Salt Lake City, UT, USA.

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November 2016

Prognostic markers in smear preparations for pancreatic endocrine neoplasms: A cytomorphologic study and statistical analysis of 20 potential prognostic features.

Cytojournal 2016 20;13:22. Epub 2016 Sep 20.

Address: Department of Pathology and Anatomical Sciences, University of Missouri, Columbia, MO, USA.

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September 2016

Impact of Continuous Improvement of Laboratory Test Result Comments on Requests for Consultation:  A Case Series.

Am J Clin Pathol 2016 May 2;145(5):666-70. Epub 2016 Mar 2.

From the Department of Pathology, University of Utah School of Medicine, Salt Lake City ARUP Laboratories, Salt Lake City, UT.

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May 2016

Cytologic separation of branchial cleft cyst from metastatic cystic squamous cell carcinoma: A multivariate analysis of nineteen cytomorphologic features.

Diagn Cytopathol 2016 Jul 9;44(7):561-7. Epub 2016 Mar 9.

Department of Pathology and Laboratory Medicine and ARUP Laboratories, University of Utah, Salt Lake City, Utah.

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July 2016

Publication outcome of abstracts presented at the AACC annual meeting.

Clin Chim Acta 2016 May 27;456:49-55. Epub 2016 Feb 27.

Department of Pathology and ARUP Laboratories, University of Utah Health Sciences Center, Salt Lake City, UT, United States. Electronic address:

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May 2016

Interobserver reproducibility for HER2/neu immunohistochemistry: A comparison of reproducibility for the HercepTest™ and the 4B5 antibody clone.

Pathol Res Pract 2016 Mar 31;212(3):190-5. Epub 2015 Dec 31.

From the Department of Pathology & Laboratory Medicine and ARUP Laboratories, Salt Lake City, UT, United States.

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March 2016

Cost-Effectiveness Analysis of Multiplex PCR with Magnetic Resonance Detection versus Empiric or Blood Culture-Directed Therapy for Management of Suspected Candidemia.

J Clin Microbiol 2016 Mar 6;54(3):718-26. Epub 2016 Jan 6.

Institute for Clinical and Experimental Pathology, ARUP Laboratories, Salt Lake City, Utah, USA Department of Pathology, University of Utah, Salt Lake City, Utah, USA Department of Medicine, University of Utah, Salt Lake City, Utah, USA

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March 2016

More on Evidence-Based Medicine.

Arch Pathol Lab Med 2016 Jan;140(1):10

Department of Pathology, University of Utah, Salt Lake City.

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January 2016

Diagnostic Error in Anatomic Pathology.

Arch Pathol Lab Med 2016 Jan;140(1)

Department of Pathology, University of Utah, Salt Lake City.

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January 2016

A Risk Assessment of the Jaffe vs Enzymatic Method for Creatinine Measurement in an Outpatient Population.

PLoS One 2015 24;10(11):e0143205. Epub 2015 Nov 24.

Department of Pathology and ARUP Laboratories, University of Utah Health Sciences Center, Salt Lake City, Utah, United States of America.

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June 2016

Cytomorphology is often insufficient to categorize non-small-cell lung carcinoma on FNA specimens.

Diagn Cytopathol 2016 Feb 23;44(2):73-9. Epub 2015 Nov 23.

Department of Pathology/ARUP Laboratories, University of Utah School of Medicine, Utah.

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February 2016

Patterns and Significance of PIM Kinases in Urothelial Carcinoma.

Appl Immunohistochem Mol Morphol 2015 Nov-Dec;23(10):717-23

*Huntsman Cancer Hospital, University of Utah †ARUP Institute for Clinical and Experimental Pathology ‡Huntsman Cancer Institute, Salt Lake City, UT.

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August 2016

A Mass Balance-Based Semiparametric Approach to Evaluate Neonatal Erythropoiesis.

AAPS J 2016 Jan 26;18(1):187-95. Epub 2015 Oct 26.

Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, 115 S. Grand Ave. S227, Iowa City, Iowa, 52242, USA.

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January 2016

When Is Rapid On-Site Evaluation Cost-Effective for Fine-Needle Aspiration Biopsy?

PLoS One 2015 28;10(8):e0135466. Epub 2015 Aug 28.

Department of Pathology, University of Utah School of Medicine and ARUP Laboratories, Salt Lake City, Utah, United States of America.

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May 2016

Laboratory medicine and value-based health care.

Am J Clin Pathol 2015 Sep;144(3):357-8

From the Department of Pathology and ARUP Laboratories, University of Utah Health Sciences Center, Salt Lake City.

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September 2015

A Cost-Effectiveness Analysis of First Trimester Non-Invasive Prenatal Screening for Fetal Trisomies in the United States.

PLoS One 2015 2;10(7):e0131402. Epub 2015 Jul 2.

Department of Pathology and ARUP Laboratories, University of Utah, Salt Lake City, Utah, United States of America.

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April 2016

A Method to Evaluate Fetal Erythropoiesis from Postnatal Survival of Fetal RBCs.

AAPS J 2015 Sep 28;17(5):1246-54. Epub 2015 May 28.

Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, 115 S. Grand Ave. S227, Iowa City, Iowa, 52242, USA.

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September 2015

Researchers should be aware of partial verification bias in diagnostic accuracy studies.

Oral Surg Oral Med Oral Pathol Oral Radiol 2015 May 14;119(5):593. Epub 2015 Feb 14.

Department of Pathology, University of Utah School of Medicine and ARUP Laboratories, Salt Lake City, Utah, USA.

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May 2015

Reporting issues in diagnostic accuracy studies for fine-needle aspiration cytology.

Acta Otorrinolaringol Esp 2015 May-Jun;66(3):183. Epub 2015 Feb 18.

Department of Pathology, University of Utah School of Medicine, Salt Lake City, Estados Unidos.

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August 2016

Effects of 49 Different Rare Hb Variants on HbA1c Measurement in Eight Methods.

J Diabetes Sci Technol 2015 Jul 17;9(4):849-56. Epub 2015 Feb 17.

Department of Pathology, University of Utah Health Sciences Center, Salt Lake City, UT, USA.

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July 2015

Physician provider type influences utilization and diagnostic utility of magnetic resonance imaging of the knee.

J Bone Joint Surg Am 2015 Jan;97(1):56-62

Department of Orthopaedic Surgery, University of Utah, 590 Wakara Way, Salt Lake City, UT 84108. E-mail address for J.D. Wylie:

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January 2015

Analytical sensitivity of four commonly used hCG point of care devices.

Clin Biochem 2015 Apr 27;48(6):448-52. Epub 2014 Dec 27.

Kaiser Permanente, TPMG Northern California Regional Laboratory, Berkeley, CA, USA. Electronic address:

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April 2015

Malignancy risk associated with the EBUS-FNA diagnostic categories nondiagnostic, benign, atypical, suspicious for malignancy, and malignant for mediastinal lymph node aspirate specimens.

J Am Soc Cytopathol 2015 Sep - Oct;4(5):276-281. Epub 2015 Jun 26.

University of Utah and ARUP Laboratories, Department of Pathology and Laboratory Medicine, Salt Lake City, Utah.

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June 2015

Verification and classification bias interactions in diagnostic test accuracy studies for fine-needle aspiration biopsy.

Cancer Cytopathol 2015 Mar 17;123(3):193-201. Epub 2014 Dec 17.

Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah.

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March 2015