Robert J Unwin

Robert J Unwin

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Robert J Unwin

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P2X7 Receptor Stimulation Is Not Required for Oxalate Crystal-Induced Kidney Injury.

Sci Rep 2019 Dec 27;9(1):20086. Epub 2019 Dec 27.

Department of Nephrology and Medical Intensive Care, Charité - Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1038/s41598-019-56560-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934555PMC
December 2019

A Case of Drug-Induced Proximal Tubular Dysfunction.

Clin J Am Soc Nephrol 2019 Sep 10;14(9):1384-1387. Epub 2019 Jun 10.

Department of Renal Medicine, University College London, London, United Kingdom; and.

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http://dx.doi.org/10.2215/CJN.01430219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6730515PMC
September 2019

A New Estimate of the Glomerular Sieving Coefficient for Retinol-Binding Protein 4 Suggests It Is Not Freely Filtered.

Kidney Int Rep 2019 Jul 29;4(7):1017-1018. Epub 2019 Apr 29.

Department of Renal Medicine, University College London Medical School, London, UK.

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http://dx.doi.org/10.1016/j.ekir.2019.04.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662157PMC
July 2019

Liquorice, Liddle, Bartter or Gitelman-how to differentiate?

Nephrol Dial Transplant 2019 01;34(1):38-39

UCL Centre for Nephrology, Royal Free Hospital, University College, London, UK.

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http://dx.doi.org/10.1093/ndt/gfy199DOI Listing
January 2019

Physiological regulation of phosphate by vitamin D, parathyroid hormone (PTH) and phosphate (Pi).

Pflugers Arch 2019 01 5;471(1):83-98. Epub 2018 Nov 5.

Centre for Nephrology, University College London (UCL), Royal Free Campus, Rowland Hill Street, London, NW3 2PF, UK.

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http://link.springer.com/10.1007/s00424-018-2231-z
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http://dx.doi.org/10.1007/s00424-018-2231-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326012PMC
January 2019

Acute saccharin infusion has no effect on renal glucose handling in normal rats in vivo.

Physiol Rep 2018 07;6(14):e13804

Department of Neuroscience, Physiology & Pharmacology, University College London, London, United Kingdom.

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http://dx.doi.org/10.14814/phy2.13804DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046642PMC
July 2018

Vitamin D deficiency is prevalent among idiopathic stone formers, but does correction pose any risk?

Urolithiasis 2017 Dec 16;45(6):535-543. Epub 2016 Dec 16.

UCL Centre for Nephrology, Department of Clinical Biochemistry, Royal Free Campus and Hospital, Rowland Hill Street, London, NW3 2PF, UK.

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http://dx.doi.org/10.1007/s00240-016-0954-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656695PMC
December 2017

A more tubulocentric view of diabetic kidney disease.

J Nephrol 2017 Dec 24;30(6):701-717. Epub 2017 Aug 24.

UCL Centre for Nephrology, UCL Medical School, Royal Free Campus, Rowland Hill Street, London, NW3 2PF, UK.

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http://dx.doi.org/10.1007/s40620-017-0423-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698396PMC
December 2017

Sequential Analysis of a Panel of Biomarkers and Pathologic Findings in a Resuscitated Rat Model of Sepsis and Recovery.

Crit Care Med 2017 Aug;45(8):e821-e830

1Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, London, United Kingdom.2Department of Nephrology, Division of Medicine, University College London, London, United Kingdom.3Hammersmith Hospital, Imperial College Renal and Transplant Centre, London, United Kingdom.4Department of cellular pathology, Royal Free Hospital, London, United Kingdom.5Center for Critical Care Nephrology, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA.

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http://dx.doi.org/10.1097/CCM.0000000000002381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511729PMC
August 2017

Hyperglycemia-induced Renal P2X7 Receptor Activation Enhances Diabetes-related Injury.

EBioMedicine 2017 May 20;19:73-83. Epub 2017 Apr 20.

UCL Centre for Nephrology, University College London, London, UK; Cardiovascular and Metabolic Diseases (CVMD) iMed, AstraZeneca, Gothenburg, Sweden.

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http://dx.doi.org/10.1016/j.ebiom.2017.04.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440600PMC
May 2017

Postprandial adjustments in renal phosphate excretion do not involve a gut-derived phosphaturic factor.

Exp Physiol 2017 04 14;102(4):462-474. Epub 2017 Mar 14.

Department of Neuroscience, Physiology and Pharmacology, University College London, London, NW3 2PF, UK.

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http://dx.doi.org/10.1113/EP086062DOI Listing
April 2017

Purinergic signaling in kidney disease.

Kidney Int 2017 02 22;91(2):315-323. Epub 2016 Oct 22.

British Heart Foundation Centre for Cardiovascular Science, The University of Edinburgh, Edinburgh, Scotland, UK.

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http://dx.doi.org/10.1016/j.kint.2016.08.029DOI Listing
February 2017

Putative tissue location and function of the SLC5 family member SGLT3.

Exp Physiol 2017 01;102(1):5-13

Cardiovascular and Metabolic Diseases, Innovative Medicines and Early Development Biotech Unit, AstraZeneca, Mölndal, Sweden.

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http://dx.doi.org/10.1113/EP086042DOI Listing
January 2017

Infrared vibrational spectroscopy: a rapid and novel diagnostic and monitoring tool for cystinuria.

Sci Rep 2016 10 10;6:34737. Epub 2016 Oct 10.

Glynn Laboratory of Bioenergetics, Institute of Structural and Molecular Biology, University College London, Gower Street, London WC1E 6BT, United Kingdom.

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http://dx.doi.org/10.1038/srep34737DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056377PMC
October 2016

Experimental type II diabetes and related models of impaired glucose metabolism differentially regulate glucose transporters at the proximal tubule brush border membrane.

Exp Physiol 2016 06 10;101(6):731-42. Epub 2016 May 10.

London Epithelial Group, Department of Neuroscience, Physiology & Pharmacology, University College London, London, UK.

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http://dx.doi.org/10.1113/EP085670DOI Listing
June 2016

Persistent severe polyuria after renal transplant.

Clin Kidney J 2016 Apr 20;9(2):180-3. Epub 2015 Oct 20.

Division of Medicine , University College London , London , UK.

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http://dx.doi.org/10.1093/ckj/sfv100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792610PMC
April 2016

Inhibition of the purinergic P2X7 receptor improves renal perfusion in angiotensin-II-infused rats.

Kidney Int 2015 Nov 24;88(5):1079-87. Epub 2015 Jun 24.

University/British Heart Foundation Centre for Cardiovascular Science, The University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1038/ki.2015.182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826596PMC
November 2015

Renal Fanconi syndrome: taking a proximal look at the nephron.

Nephrol Dial Transplant 2015 Sep 9;30(9):1456-60. Epub 2014 Dec 9.

Centre for Nephrology, University College London, London, UK.

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http://dx.doi.org/10.1093/ndt/gfu377DOI Listing
September 2015

Magnesium: The Disregarded Cation.

Mayo Clin Proc 2015 Aug;90(8):993-5

UCL Centre for Nephrology and Department of Neuroscience, Physiology and Pharmacology, University College London, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.mayocp.2015.06.011DOI Listing
August 2015

What is nephrocalcinosis?

Kidney Int 2015 Jul 25;88(1):35-43. Epub 2015 Mar 25.

UCL Centre for Nephrology, Royal Free Campus and Hospital, University College London, London, UK.

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http://dx.doi.org/10.1038/ki.2015.76DOI Listing
July 2015

The urinary proteome and metabonome differ from normal in adults with mitochondrial disease.

Kidney Int 2015 Mar 10;87(3):610-22. Epub 2014 Sep 10.

Medical Research Council Centre for Neuromuscular Diseases, National Hospital for Neurology and Neurosurgery, University College London Institute of Neurology, London, UK.

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http://dx.doi.org/10.1038/ki.2014.297DOI Listing
March 2015

Experimental and regional variations in Na+-dependent and Na+-independent phosphate transport along the rat small intestine and colon.

Physiol Rep 2015 Jan 27;3(1). Epub 2015 Jan 27.

Department of Neuroscience, Physiology & Pharmacology, University College London, London, UK UCL Centre for Nephrology, University College London, London, UK.

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http://dx.doi.org/10.14814/phy2.12281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387749PMC
January 2015

Exaggerated renal fibrosis in P2X4 receptor-deficient mice following unilateral ureteric obstruction.

Nephrol Dial Transplant 2014 Jul 25;29(7):1350-61. Epub 2014 Feb 25.

Imperial College Renal and Transplant Centre, Hammersmith Hospital, Imperial College London, London, UK.

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https://academic.oup.com/ndt/article-lookup/doi/10.1093/ndt/
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http://dx.doi.org/10.1093/ndt/gfu019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4071051PMC
July 2014

Mistargeting of peroxisomal EHHADH and inherited renal Fanconi's syndrome.

N Engl J Med 2014 Jan;370(2):129-38

From the Centre for Nephrology (E.D.K., H.C.S., D.B., G.J., H.C., A.M.H., R.J.U., R.K.) and Institute of Child Health (D.B., R.K.), University College London, and Biomolecular Medicine, Imperial College London (S.L.R., A.D.W., E.H., J.K.N.) - both in London; the Departments of Medical Cell Biology (M.R., C.B., D.P., C.S., R. Warth), Internal Medicine III (K.R.), Internal Medicine II (S.W.R.), and Molecular and Cellular Anatomy (R. Witzgall) and the Institutes of Functional Genomics (J.R., K.E., N.A., P.J.O., K.D.) and Pathology (J.S.), University of Regensburg, and the Department of Radiology, Barmherzige Brueder Hospital (N.Z.) - all in Regensburg, Germany; the National Human Genome Research Institute (A.H.-W., S.L.R., H.C.S., K.O., I.B., D.M.K., W.A.G., R.K.) and National Heart, Lung, and Blood Institute (Y.I.), National Institutes of Health, Bethesda, MD; the Division of Pediatric Nephrology, University of Florida, Jacksonville (A.T., M.I.); the Genome Biology Department, Australian National University, Canberra, ACT, Australia (M.A.-B.); Kitasato University Medical Center, Saitama, Japan (H.N.); and the Department of Pathology, Northwestern University, Chicago (Y.J., J.K.R.).

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http://dx.doi.org/10.1056/NEJMoa1307581DOI Listing
January 2014

Is the inflammasome a potential therapeutic target in renal disease?

BMC Nephrol 2014 Jan 23;15:21. Epub 2014 Jan 23.

Imperial College Kidney and Transplant Institute, Hammersmith Hospital, Imperial College London, London, UK.

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http://dx.doi.org/10.1186/1471-2369-15-21DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918225PMC
January 2014

Effect of P2X4 and P2X7 receptor antagonism on the pressure diuresis relationship in rats.

Front Physiol 2013 25;4:305. Epub 2013 Oct 25.

University/British Heart Foundation Centre for Cardiovascular Science, The University of Edinburgh Edinburgh, UK.

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http://dx.doi.org/10.3389/fphys.2013.00305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3807716PMC
November 2013

Nephrocalcinosis (enamel renal syndrome) caused by autosomal recessive FAM20A mutations.

Nephron Physiol 2012 23;122(1-2):1-6. Epub 2013 Feb 23.

Centre for Nephrology, University College London, London, UK.

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http://dx.doi.org/10.1159/000349989DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782194PMC
October 2013

The relationship between P2X4 and P2X7: a physiologically important interaction?

Front Physiol 2013 15;4:216. Epub 2013 Aug 15.

Centre for Nephrology, UCL Medical School, University College London London, UK.

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http://dx.doi.org/10.3389/fphys.2013.00216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744038PMC
August 2013

The role of the gastrointestinal tract in phosphate homeostasis in health and chronic kidney disease.

Curr Opin Nephrol Hypertens 2013 Jul;22(4):481-7

London Epithelial Group, Department of Neuroscience, Physiology & Pharmacology, University College London Medical School, London, UK.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/MNH.0b013e3283621310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196778PMC
July 2013

Urinary vesicles: in splendid isolation.

Nephrol Dial Transplant 2013 Jun 24;28(6):1332-5. Epub 2013 Jan 24.

UCL Centre for Nephrology, UCL Medical School (Royal Free Campus and Hospital), University College London, London, UK.

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http://dx.doi.org/10.1093/ndt/gfs599DOI Listing
June 2013

Protease stimulation of renal sodium reabsorption in vivo by activation of the collecting duct epithelial sodium channel (ENaC).

Nephrol Dial Transplant 2013 Apr 4;28(4):839-45. Epub 2012 Dec 4.

INSERM U-1088, Amiens, France.

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http://dx.doi.org/10.1093/ndt/gfs486DOI Listing
April 2013

ATP and arterial calcification.

Eur J Clin Invest 2013 Apr 10;43(4):405-12. Epub 2013 Feb 10.

UCL Centre for Nephrology, UCL Medical School, London, UK.

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http://dx.doi.org/10.1111/eci.12055DOI Listing
April 2013

Renal tubular disorders.

Clin Med (Lond) 2012 Oct;12(5):476-9

UCL Centre for Nephrology, Royal Free Campus and Hospital, University College London Medical School.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4953774PMC
http://dx.doi.org/10.7861/clinmedicine.12-5-476DOI Listing
October 2012

Pathogenesis of calcineurin inhibitor-induced hypertension.

J Nephrol 2012 May-Jun;25(3):269-75

Department of Internal Medicine-Nephrology, Erasmus Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.5301/jn.5000174DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048819PMC
September 2012

Back to the future: renal tubular acidosis then and now.

Authors:
Robert J Unwin

QJM 2012 Sep 1;105(9):915-6. Epub 2012 Aug 1.

University College, London, NW3 2PF, UK.

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http://dx.doi.org/10.1093/qjmed/hcs134DOI Listing
September 2012

P2 purinoceptors: Renal pathophysiology and therapeutic potential.

Clin Nephrol 2012 Aug;78(2):154-63

UCL Center for Nephrology, Royal Free Hospital, University College London, UK.

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http://dx.doi.org/10.5414/cn107325DOI Listing
August 2012

In memoriam: Oliver M. Wrong.

Kidney Int 2012 Jul;82(2):121-2

Department of Medicine, Upstate Medical University, Syracuse, NY, USA.

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http://dx.doi.org/10.1038/ki.2012.183DOI Listing
July 2012

Is the albumin retrieval hypothesis a paradigm shift for nephrology?

J Am Soc Nephrol 2012 Apr 15;23(4):569-71. Epub 2012 Mar 15.

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http://dx.doi.org/10.1681/ASN.2012020207DOI Listing
April 2012

A potential therapeutic role for P2X7 receptor (P2X7R) antagonists in the treatment of inflammatory diseases.

Expert Opin Investig Drugs 2011 Jul 21;20(7):897-915. Epub 2011 Apr 21.

Imperial College London, Hammersmith Hospital, Renal Section, Department of Medicine, London, UK.

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http://dx.doi.org/10.1517/13543784.2011.578068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114873PMC
July 2011

Multiphoton imaging of the functioning kidney.

J Am Soc Nephrol 2011 Jul 30;22(7):1297-304. Epub 2011 Jun 30.

University College London Centre for Nephrology, Royal Free Hospital, Rowland Hill Street, London NW3 2PF, United Kingdom.

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http://dx.doi.org/10.1681/ASN.2010101054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137577PMC
July 2011

Sodium and water handling after gastric bypass surgery in a rat model.

Surg Obes Relat Dis 2011 Jan-Feb;7(1):68-73. Epub 2010 Apr 1.

Department of Investigative Medicine, Imperial Weight Centre, Imperial College London, London, United Kingdom.

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http://dx.doi.org/10.1016/j.soard.2010.03.286DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715839PMC
May 2011

Pathophysiology and management of hypokalemia: a clinical perspective.

Nat Rev Nephrol 2011 Feb;7(2):75-84

Centre for Nephrology, Royal Free Hospital, University College London, Rowland Hill Street, London NW3 2PF, UK.

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http://dx.doi.org/10.1038/nrneph.2010.175DOI Listing
February 2011

Clinical hypokalemia and hyperkalemia at the bedside.

J Nephrol 2010 Nov-Dec;23 Suppl 16:S105-11

UCL Centre for Nephrology, Royal Free Hospital, University College London, London, UK.

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February 2011

Direct micropuncture evidence that matrix extracellular phosphoglycoprotein inhibits proximal tubular phosphate reabsorption.

Nephrol Dial Transplant 2010 Oct 14;25(10):3191-5. Epub 2010 May 14.

Centre for Nephrology, University College London Medical School, Royal Free Campus, Rowland Hill Street, London NW3 2PF, UK.

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http://dx.doi.org/10.1093/ndt/gfq263DOI Listing
October 2010

Erythropoietin regulates intestinal iron absorption in a rat model of chronic renal failure.

Kidney Int 2010 Oct 14;78(7):660-7. Epub 2010 Jul 14.

Institute of Structural and Molecular Biology, University College London, London, UK.

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http://dx.doi.org/10.1038/ki.2010.217DOI Listing
October 2010

Phosphate homeostasis and the renal-gastrointestinal axis.

Am J Physiol Renal Physiol 2010 Aug 9;299(2):F285-96. Epub 2010 Jun 9.

Dept. of Neuroscience, Physiology, and Pharmacology, Univ. College London Medical School, UK.

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http://dx.doi.org/10.1152/ajprenal.00508.2009DOI Listing
August 2010

Subclinical tubular injury in HIV-infected individuals on antiretroviral therapy: a cross-sectional analysis.

Am J Kidney Dis 2009 Dec 23;54(6):1034-42. Epub 2009 Sep 23.

Department of Cell and Developmental Biology, University College of London, London, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S02726386090102
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http://dx.doi.org/10.1053/j.ajkd.2009.07.012DOI Listing
December 2009

Nucleotides downregulate aquaporin 2 via activation of apical P2 receptors.

J Am Soc Nephrol 2009 Jul 7;20(7):1480-90. Epub 2009 May 7.

Urinary System Physiology Unit, Department of Veterinary Basic Sciences, Royal Veterinary College, Camden Campus, Royal College Street, London NW1 0TU, United Kingdom.

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http://dx.doi.org/10.1681/ASN.2008070686DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709676PMC
July 2009

Multiphoton imaging reveals differences in mitochondrial function between nephron segments.

J Am Soc Nephrol 2009 Jun 21;20(6):1293-302. Epub 2009 May 21.

Department of Cell and Developmental Biology, University College London, London WC1E 6BT, UK.

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http://dx.doi.org/10.1681/ASN.2008070759DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689904PMC
June 2009

Insulin uptake across the luminal membrane of the rat proximal tubule in vivo and in vitro.

Am J Physiol Renal Physiol 2009 May 4;296(5):F1227-37. Epub 2009 Mar 4.

Institute of Physical Engineering, Brno University of Technology, Brno, Czech Republic.

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http://dx.doi.org/10.1152/ajprenal.90351.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2681358PMC
May 2009

Matrix extracellular phosphoglycoprotein inhibits phosphate transport.

J Am Soc Nephrol 2008 Dec 12;19(12):2313-20. Epub 2008 Nov 12.

Department of Physiology, University College London Medical School, Royal Free Campus, Rowland Hill Street, London NW3 2PF.

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http://dx.doi.org/10.1681/ASN.2008030315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2588094PMC
December 2008

Application of proteomic techniques to the study of urine and renal tissue.

Proteomics Clin Appl 2008 Dec 22;2(12):1564-74. Epub 2008 Oct 22.

Chair of Nephrology, Second University of Naples, Naples, Italy; Proteomic and Biomolecular Mass Spectrometry Center, Institute of Food Science and Technology, CNR, Avellino, Italy.

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http://dx.doi.org/10.1002/prca.200800035DOI Listing
December 2008

Lysosomal enzymuria is a feature of hereditary Fanconi syndrome and is related to elevated CI-mannose-6-P-receptor excretion.

Nephrol Dial Transplant 2008 Sep 3;23(9):2795-803. Epub 2008 Jan 3.

Department of Clinical Biochemistry, Addenbrooke's Hospital, Box 232, Hills Road, Cambridge CB2 2QR, UK.

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https://academic.oup.com/ndt/article-lookup/doi/10.1093/ndt/
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http://dx.doi.org/10.1093/ndt/gfm898DOI Listing
September 2008

Sodium-dependent regulation of renal amiloride-sensitive currents by apical P2 receptors.

J Am Soc Nephrol 2008 Apr 30;19(4):731-42. Epub 2008 Jan 30.

Department of Veterinary Basic Sciences, Royal Veterinary College, Camden Campus, Royal College Street, London NW1 0TU, UK.

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http://dx.doi.org/10.1681/ASN.2007040443DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2390963PMC
April 2008

Matrix extracellular phosphoglycoprotein causes phosphaturia in rats by inhibiting tubular phosphate reabsorption.

Nephrol Dial Transplant 2008 Feb 23;23(2):730-3. Epub 2007 Nov 23.

Department of Physiology and Centre for Nephrology, University College London, Hampstead Campus, Rowland Hill Street, London NW3 2PF, UK.

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http://dx.doi.org/10.1093/ndt/gfm535DOI Listing
February 2008

Increased expression of the pro-apoptotic ATP-sensitive P2X7 receptor in experimental and human glomerulonephritis.

Nephrol Dial Transplant 2007 Feb 13;22(2):386-95. Epub 2006 Oct 13.

Epithelial Transport and Cell Biology Group, Department of Physiology, University College London (Hampstead Campus), Rowland Hill Street, London NW3 2PF, UK.

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http://www.ucl.ac.uk/ani/GB's%20PDF%20file%20copies/CV1346.p
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http://ndt.oxfordjournals.org/cgi/doi/10.1093/ndt/gfl589
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http://dx.doi.org/10.1093/ndt/gfl589DOI Listing
February 2007

The not so 'mighty chondrion': emergence of renal diseases due to mitochondrial dysfunction.

Nephron Physiol 2007 8;105(1):p1-10. Epub 2006 Nov 8.

Centre for Nephrology and Department of Physiology (Epithelial Transport and Cell Biology Group), Royal Free and University College Medical School, London, UK.

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http://dx.doi.org/10.1159/000096860DOI Listing
February 2007

Signalling through phospholipase C interferes with clathrin-mediated endocytosis.

Cell Signal 2007 Jan 6;19(1):42-51. Epub 2006 Jun 6.

Department of Physiology, University College London, London WC1E 6JJ UK.

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http://dx.doi.org/10.1016/j.cellsig.2006.05.023DOI Listing
January 2007

Antagonism of endogenous putative P2Y receptors reduces the growth of MDCK-derived cysts cultured in vitro.

Am J Physiol Renal Physiol 2007 Jan 18;292(1):F15-25. Epub 2006 Jul 18.

Epithelial Transport and Cell Biology Group, Centre for Nephrology and Dept. of Physiology, Royal Free and Univ. College Medical School, Rowland Hill St., London NW3 2PF, UK.

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http://dx.doi.org/10.1152/ajprenal.00103.2006DOI Listing
January 2007

Intraluminal ATP concentrations in rat renal tubules.

J Am Soc Nephrol 2006 Jul 21;17(7):1841-7. Epub 2006 Jun 21.

Department of Physiology and Centre for Nephrology, University College London, Hampstead Campus, London NW3 2PF, UK.

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http://dx.doi.org/10.1681/ASN.2005111171DOI Listing
July 2006

Intestinal phosphate absorption and the effect of vitamin D: a comparison of rats with mice.

Exp Physiol 2006 May 23;91(3):531-7. Epub 2006 Jan 23.

Department of Physiology, Royal Free and University College Medical School, Royal Free Campus, Rowland Hill Street, London NW3 2PF, UK.

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http://dx.doi.org/10.1113/expphysiol.2005.032516DOI Listing
May 2006

Distal renal tubular acidosis in association with HIV infection and AIDS.

Nephrol Dial Transplant 2006 May 31;21(5):1420-2. Epub 2006 Jan 31.

Department of Nephrology, Royal Free Hospital, Greater London, UK.

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May 2006

Bartter's and Gitelman's syndromes: their relationship to the actions of loop and thiazide diuretics.

Curr Opin Pharmacol 2006 Apr 20;6(2):208-13. Epub 2006 Feb 20.

Centre for Nephrology and Department of Physiology, Royal Free and University College Medical School, University College London, Hampstead Campus, Rowland Hill Street, London NW3 2PF, UK.

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http://dx.doi.org/10.1016/j.coph.2006.01.002DOI Listing
April 2006

Immunolocalization of ectonucleotidases along the rat nephron.

Am J Physiol Renal Physiol 2006 Feb 27;290(2):F550-60. Epub 2005 Sep 27.

Department of Physiology, Royal Free and University College Medical School, Rowland Hill St., London NW3 2PF, UK.

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February 2006

Dent's disease.

Nephrol Dial Transplant 2005 Oct 19;20(10):2284-5. Epub 2005 Jul 19.

Department of Nephrology, UCL Hospitals Trust, Middlesex Hospital, Mortimer Street, London W1T 3AA, UK.

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http://dx.doi.org/10.1093/ndt/gfh968DOI Listing
October 2005

Regulatory interdependence of cloned epithelial Na+ channels and P2X receptors.

J Am Soc Nephrol 2005 Sep 6;16(9):2586-97. Epub 2005 Jul 6.

Department of Physiology and Centre for Nephrology, Royal Free and University College Medical School, University College London, London NW3 2PF, UK.

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http://dx.doi.org/10.1681/ASN.2005020130DOI Listing
September 2005

Renal tubular acidosis: developments in our understanding of the molecular basis.

Int J Biochem Cell Biol 2005 Jun;37(6):1151-61

Centre for Nephrology, Royal Free and University College Medical School, London NW3, UK.

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June 2005

Proteomic analysis of plasma membrane vesicles isolated from the rat renal cortex.

Proteomics 2005 Jan;5(1):101-12

Ludwig Institute for Cancer Research, University College London Branch, London W1W 7BS, UK.

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http://dx.doi.org/10.1002/pmic.200400886DOI Listing
January 2005

Simultaneous determination of anions in nanoliter volumes.

Kidney Int 2005 Jan;67(1):357-63

School of Biological and Chemical Sciences, Birkbeck College, London, UK.

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http://dx.doi.org/10.1111/j.1523-1755.2005.00089.xDOI Listing
January 2005

A guide to renal stone disease.

Practitioner 2005 Jan;249(1666):18, 20, 24 passim

Centre for Nephrology, Royal Free and University College Medical School, London.

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January 2005

Quantitative amino acid and proteomic analysis: very low excretion of polypeptides >750 Da in normal urine.

Kidney Int 2004 Nov;66(5):1994-2003

Department of Clinical Biochemistry, Addenbrooke's Hospital, Cambridge, United Kingdom.

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November 2004

The P2X7 ATP receptor modulates renal cyst development in vitro.

Biochem Biophys Res Commun 2004 Sep;322(2):434-9

Nephrology and Physiology, Royal Free Campus, Institute of Child Health, University College London, London, UK.

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September 2004

Glomerular expression of the ATP-sensitive P2X receptor in diabetic and hypertensive rat models.

Kidney Int 2004 Jul;66(1):157-66

Centre for Nephrology and Department of Physiology, Royal Free and University College Medical School, University College London, London, United Kingdom.

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July 2004

Urinary proteomics of renal Fanconi syndrome.

Contrib Nephrol 2004 ;141:155-69

Ludwig Institute for Cancer Research, Department of Biochemistry and Molecular Biology, University College London, Centre for Nephrology, Department of Physiology, Royal Free and University College Medical School, London, UK.

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January 2004

The isolated polycystin-1 cytoplasmic COOH terminus prolongs ATP-stimulated Cl- conductance through increased Ca2+ entry.

Am J Physiol Renal Physiol 2003 Dec 29;285(6):F1168-78. Epub 2003 Jul 29.

Laboratory of Cardiological Sciences, Gerontology Research Center, Division of Renal Medicine, Johns Hopkins Bayview Medical Center, 4940 Eastern Avenue, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1152/ajprenal.00171.2003DOI Listing
December 2003

Extended pharmacological profiles of rat P2Y2 and rat P2Y4 receptors and their sensitivity to extracellular H+ and Zn2+ ions.

Br J Pharmacol 2003 Dec 27;140(7):1177-86. Epub 2003 Oct 27.

Department of Physiology, Centre for Nephrology, Royal Free Campus, Royal Free and University College Medical School, University College London, Rowland Hill Street, Hampstead, London NW3 2PF, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1574132PMC
December 2003

Purinergic signaling along the renal tubule: the current state of play.

News Physiol Sci 2003 Dec;18:237-41

Centre for Nephrology, Department of Physiology, and Autonomic Neuroscience Institute, Royal Free and University College Medical School, London W1W 7EY, United Kingdom.

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December 2003

Diabetes increases facilitative glucose uptake and GLUT2 expression at the rat proximal tubule brush border membrane.

J Physiol 2003 Nov 8;553(Pt 1):137-45. Epub 2003 Sep 8.

Department of Physiology and Centre for Nephrology, Royal Free and University College Medical School, London, UK.

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November 2003

Polyphenotypic expression of mitochondrial toxicity caused by nucleoside reverse transcriptase inhibitors.

Antivir Ther 2003 Jun;8(3):253-7

Department of Sexually Transmitted Diseases, Royal Free and University College Medical School, University College London and Camden Primary Care Trust, London, UK.

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June 2003

ETA receptor-mediated Ca2+ signaling in thin descending limbs of Henle's loop: impairment in genetic hypertension.

Kidney Int 2003 Apr;63(4):1276-84

Centre for Nephrology and Department of Physiology, Royal Free and University College Medical School, University College London, UK.

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April 2003

The isolated C-terminus of polycystin-1 promotes increased ATP-stimulated chloride secretion in a collecting duct cell line.

Clin Sci (Lond) 2003 Mar;104(3):217-21

Division of Renal Medicine, Johns Hopkins Bayview Medical Center, 4940 Eastern Avenue, Baltimore, MD 21224, USA.

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March 2003