Robert J Konrad

Robert J Konrad

UNVERIFIED PROFILE

Are you Robert J Konrad?   Register this Author

Register author
Robert J Konrad

Robert J Konrad

Publications by authors named "Robert J Konrad"

Are you Robert J Konrad?   Register this Author

83Publications

1587Reads

39Profile Views

High-dose vitamin D reduces circulating hepcidin concentrations: A pilot, randomized, double-blind, placebo-controlled trial in healthy adults.

Clin Nutr 2017 08 27;36(4):980-985. Epub 2016 Jun 27.

Nutrition and Health Sciences Program, Laney Graduate School, Emory University, Atlanta, GA 30322, USA; Division of Endocrinology, Metabolism and Lipids, Emory University School of Medicine, Atlanta, GA 30322, USA; Atlanta Veterans Administration Medical Center (VAMC), Decatur, GA 30033, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clnu.2016.06.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5191989PMC
August 2017

An innovative and highly drug-tolerant approach for detecting neutralizing antibodies directed to therapeutic antibodies.

Bioanalysis 2016 Oct 5;8(20):2157-68. Epub 2016 Sep 5.

Lilly Research Laboratories, Eli Lilly & Company, Indianapolis, IN 46285, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4155/bio-2016-0161DOI Listing
October 2016

A dual-monoclonal, sandwich immunoassay specific for glucagon like peptide-19-36/7 (GLP-19-36/7).

Clin Biochem 2016 Aug 18;49(12):897-902. Epub 2016 May 18.

From the Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN, 46285, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clinbiochem.2016.03.014DOI Listing
August 2016

Circulating Hepcidin-25 Is Reduced by Endogenous Estrogen in Humans.

PLoS One 2016 11;11(2):e0148802. Epub 2016 Feb 11.

Department of Endocrinology, Metabolism and Diabetes, Departments of Medicine and Molecular Medicine and Surgery, Karolinska Institutet at Karolinska University Hospital, S-141 86 Stockholm, Sweden.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0148802PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750915PMC
July 2016

A Highly Sensitive and Drug-Tolerant Anti-Drug Antibody Screening Assay for Ixekizumab using Affinity Capture Elution.

J Invest Dermatol 2016 07 30;136(7):1513-1515. Epub 2016 Mar 30.

Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jid.2016.01.040DOI Listing
July 2016

Phase 3 Trials of Ixekizumab in Moderate-to-Severe Plaque Psoriasis.

N Engl J Med 2016 Jul 8;375(4):345-56. Epub 2016 Jun 8.

From the Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago (K.B.G.); Oregon Medical Research Center, Portland (A.B.); K. Papp Clinical Research and Probity Medical Research, Waterloo, ON (K.A.P.), and the Department of Medicine, Division of Dermatology, Dalhousie University, Halifax, NS (R.G.L.) - both in Canada; the Department of Dermatology, University of Münster, Münster (T.L.), and SCIderm Research Institute and Dermatologikum Hamburg, Hamburg (K.R.) - both in Germany; the Department of Dermatology, Jichi Medical University, Shimotsuke-shi, Japan (M.O.); Lilly Research Laboratories, Eli Lilly, Indianapolis (D.A., S.G.B., D.K.B., G.S.C., J.E., R.J.K., T.M.M., B.J.N., O.O.O., R.J.S., F.Z., L.M.); and the Department of Dermatology, Saint Louis University School of Medicine, St. Louis (C.L.L.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMoa1512711DOI Listing
July 2016

Affinity capture elution bridging assay: A novel immunoassay format for detection of anti-therapeutic protein antibodies.

J Immunol Methods 2016 Apr 10;431:45-51. Epub 2016 Feb 10.

Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jim.2016.02.008DOI Listing
April 2016

Circulating Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Predicts Future Risk of Cardiovascular Events Independently of Established Risk Factors.

Circulation 2016 Mar 19;133(13):1230-9. Epub 2016 Feb 19.

From the Unit of Cardiovascular Epidemiology, Institute of Environmental Medicine, Stockholm, Sweden (K.L., U.d.F.); Cardiovascular Genetics and Genomics Group, Cardiovascular Medicine Unit, Department of Medicine (A.M., F.M.v.H., J.Ö., A.H.) and Department of Medicine (M.-L.H.), Solna, Karolinska Institutet, Stockholm, Sweden; Pharmatherapeutics Clinical Research, Pfizer Worldwide R&D, Sollentuna, Sweden (A.M.); Research Statistics, Pfizer Worldwide R&D, Cambridge, MA (C.H.); Lilly Research Laboratories, Eli Lilly and Co, Indianapolis, IN (J.S.T., R.J.K.); and Cardiology Unit, Karolinska University Hospital, Stockholm, Sweden (U.d.F.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCULATIONAHA.115.018531DOI Listing
March 2016

Novel sandwich immunoassays for the measurement of total and active FGF21.

Bioanalysis 2014 ;6(24):3283-93

Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4155/bio.14.241DOI Listing
August 2015

GLP-1 receptor activation modulates appetite- and reward-related brain areas in humans.

Diabetes 2014 Dec 28;63(12):4186-96. Epub 2014 Jul 28.

Diabetes Center, Department of Internal Medicine, VU University Medical Center, Amsterdam, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2337/db14-0849DOI Listing
December 2014

Isolation and characterization of the circulating truncated form of PCSK9.

J Lipid Res 2014 07 28;55(7):1505-14. Epub 2014 Apr 28.

Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1194/jlr.M049346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076096PMC
July 2014

Circulating PCSK9 is a strong determinant of plasma triacylglycerols and total cholesterol in homozygous carriers of apolipoprotein ε2.

Clin Sci (Lond) 2014 May;126(9):679-84

*Department of Internal Medicine, Divisions of General Internal Medicine and Endocrinology, Cardiovascular Research Institute Maastricht, Maastricht University Medical Centre, Maasctricht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1042/CS20130556DOI Listing
May 2014

Serum hepcidin levels are associated with obesity but not liver disease.

Obesity (Silver Spring) 2014 Mar 17;22(3):836-41. Epub 2013 Dec 17.

Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/oby.20403DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692602PMC
March 2014

The role of vitamin D in regulating the iron-hepcidin-ferroportin axis in monocytes.

J Clin Transl Endocrinol 2014 Mar;1(1):19-25

Division of Endocrinology, Metabolism and Lipids, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA ; Atlanta Veterans Affairs Medical Center, Atlanta, GA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jcte.2014.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119757PMC
March 2014

Hepcidin-25 concentrations are markedly increased in patients with chronic kidney disease and are inversely correlated with estimated glomerular filtration rates.

J Clin Lab Anal 2013 Nov;27(6):504-10

Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcla.21634DOI Listing
November 2013

Development of a quantitative biochemical and cellular sphingomyelin synthase assay using mass spectrometry.

Anal Biochem 2013 Jul 25;438(1):61-6. Epub 2013 Mar 25.

Lilly Research Laboratories, Eli Lilly & Company, Indianapolis, IN 46285, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ab.2013.03.016DOI Listing
July 2013

A novel high-sensitivity electrochemiluminescence (ECL) sandwich immunoassay for the specific quantitative measurement of plasma glucagon.

Clin Biochem 2012 Dec 4;45(18):1640-4. Epub 2012 Aug 4.

Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clinbiochem.2012.07.111DOI Listing
December 2012

Determination of cathepsin S abundance and activity in human plasma and implications for clinical investigation.

Anal Biochem 2012 Nov 23;430(2):130-7. Epub 2012 Aug 23.

Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S000326971200418
Publisher Site
http://dx.doi.org/10.1016/j.ab.2012.08.011DOI Listing
November 2012

Glycerolipid acyltransferases in triglyceride metabolism and energy homeostasis-potential as drug targets.

Endocr Metab Immune Disord Drug Targets 2012 Jun;12(2):197-206

Lilly Research Laboratories, 359 Merrill Street, Indianapolis, IN 46285, USA.

View Article

Download full-text PDF

Source
June 2012

Common and low-frequency genetic variants in the PCSK9 locus influence circulating PCSK9 levels.

Arterioscler Thromb Vasc Biol 2012 Jun 29;32(6):1526-34. Epub 2012 Mar 29.

Cardiovascular Genetics and Genomics Group, Center for Molecular Medicine, L8:02, Karolinska University Hospital Solna, SE-17176 Stockholm, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/ATVBAHA.111.240549DOI Listing
June 2012

Development of a novel radioimmunoassay to detect autoantibodies to amyloid beta peptides in the presence of a cross-reactive therapeutic antibody.

J Pharm Biomed Anal 2011 Dec 10;56(5):1029-34. Epub 2011 Aug 10.

Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jpba.2011.08.006DOI Listing
December 2011

Plasma proprotein convertase subtilisin kexin type 9 is a heritable trait of familial combined hyperlipidaemia.

Clin Sci (Lond) 2011 Nov;121(9):397-403

Department of Internal Medicine, Division of General Internal Medicine, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1042/CS20110129DOI Listing
November 2011

Dual-monoclonal, sandwich immunoassay specific for glucose-dependent insulinotropic peptide1-42, the active form of the incretin hormone.

Clin Chem 2011 Jun 22;57(6):849-55. Epub 2011 Apr 22.

Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1373/clinchem.2010.159954DOI Listing
June 2011

Effects of currently prescribed LDL-C-lowering drugs on PCSK9 and implications for the next generation of LDL-C-lowering agents.

Lipids Health Dis 2011 Feb 28;10:38. Epub 2011 Feb 28.

Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1476-511X-10-38DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055818PMC
February 2011

Circulating proprotein convertase subtilisin kexin type 9 has a diurnal rhythm synchronous with cholesterol synthesis and is reduced by fasting in humans.

Arterioscler Thromb Vasc Biol 2010 Dec 30;30(12):2666-72. Epub 2010 Sep 30.

Department of Endocrinology, Center for Biosciences and Nutrition, Karolinska Institutet at Karolinska University Hospital, Huddinge, Stockholm, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/ATVBAHA.110.214130DOI Listing
December 2010

Serum PCSK9 is associated with multiple metabolic factors in a large Han Chinese population.

Atherosclerosis 2010 Dec 30;213(2):632-6. Epub 2010 Oct 30.

Department of Endocrinology, The First Affiliated Hospital, Nanjing Medical University, Nanjing, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.atherosclerosis.2010.09.027DOI Listing
December 2010

Comparison of assay formats for drug-tolerant immunogenicity testing.

Bioanalysis 2010 Dec;2(12):1961-9

Lilly Research Laboratories, Eli Lilly & Company, Indianapolis, IN 46285, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4155/bio.10.136DOI Listing
December 2010

A dual-monoclonal sandwich ELISA specific for hepcidin-25.

Clin Chem 2010 Nov 16;56(11):1725-32. Epub 2010 Sep 16.

Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA.

View Article

Download full-text PDF

Source
http://www.clinchem.org/cgi/doi/10.1373/clinchem.2010.151522
Publisher Site
http://dx.doi.org/10.1373/clinchem.2010.151522DOI Listing
November 2010

Development of a novel sandwich ELISA for measuring cell lysate ABCA1 protein levels.

Lipids 2010 Aug 17;45(8):757-64. Epub 2010 Jul 17.

Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11745-010-3448-6DOI Listing
August 2010

Fenofibrate treatment increases human serum proprotein convertase subtilisin kexin type 9 levels.

J Lipid Res 2010 Feb 8;51(2):345-51. Epub 2009 Sep 8.

Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA.

View Article

Download full-text PDF

Source
http://www.jlr.org/content/51/2/345.full.pdf
Web Search
http://www.jlr.org/cgi/doi/10.1194/jlr.M000620
Publisher Site
http://dx.doi.org/10.1194/jlr.M000620DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2803236PMC
February 2010

Healthy individuals carrying the PCSK9 p.R46L variant and familial hypercholesterolemia patients carrying PCSK9 p.D374Y exhibit lower plasma concentrations of PCSK9.

Clin Chem 2009 Dec 1;55(12):2153-61. Epub 2009 Oct 1.

Centre for Cardiovascular Genetics, British Heart Foundation Laboratories, The Royal Free and University College London Medical School, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1373/clinchem.2009.129759DOI Listing
December 2009

Longitudinal studies of cardiac troponin-I concentrations in serum from male Sprague Dawley rats: baseline reference ranges and effects of handling and placebo dosing on biological variability.

Toxicol Pathol 2009 Oct 21;37(6):754-60. Epub 2009 Aug 21.

Department of Pathology, Lilly Research Laboratories, A Division of Eli Lilly and Company, Indianapolis, IN 46285, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/0192623309343777DOI Listing
October 2009

The microsomal cardiolipin remodeling enzyme acyl-CoA lysocardiolipin acyltransferase is an acyltransferase of multiple anionic lysophospholipids.

J Lipid Res 2009 May 15;50(5):945-56. Epub 2008 Dec 15.

Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1194/jlr.M800567-JLR200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666181PMC
May 2009

The development of methodology for clinical measurement of 5-lipoxygenase pathway intermediates from human peripheral blood mononuclear cells.

J Pharm Biomed Anal 2008 Dec 30;48(5):1397-403. Epub 2008 Sep 30.

Lilly Research Laboratories, Eli Lilly & Company, Indianapolis, IN 46285, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jpba.2008.09.034DOI Listing
December 2008

Further LDL cholesterol lowering through targeting PCSK9 for coronary artery disease.

Endocr Metab Immune Disord Drug Targets 2008 Dec;8(4):238-43

Lilly Research Laboratories, Indianapolis, IN 46285, USA.

View Article

Download full-text PDF

Source
December 2008

A novel method for quantitative measurement of a biomarker in the presence of a therapeutic monoclonal antibody directed against the biomarker.

J Pharm Biomed Anal 2008 Nov 25;48(3):897-901. Epub 2008 Jul 25.

Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jpba.2008.07.012DOI Listing
November 2008

Ultrasensitive cross-species measurement of cardiac troponin-I using the Erenna immunoassay system.

Toxicol Pathol 2008 Oct 22;36(6):777-82. Epub 2008 Jul 22.

Department of Pathology, Lilly Research Laboratories, Greenfield, Indiana 46140, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/0192623308322016DOI Listing
October 2008

Peroxisome proliferator-activated receptor alpha agonists regulate cholesterol ester transfer protein.

Lipids 2008 Jul 15;43(7):611-8. Epub 2008 May 15.

Cardiovascular Research, Lilly Research Laboratories, Eli Lilly & Company, Indianapolis, IN 46285, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11745-008-3187-0DOI Listing
July 2008

Secreted proprotein convertase subtilisin/kexin type 9 reduces both hepatic and extrahepatic low-density lipoprotein receptors in vivo.

Biochem Biophys Res Commun 2008 Jun 10;370(4):634-40. Epub 2008 Apr 10.

Lilly Research Laboratories, Eli Lilly & Company, Cardiovascular Research, 355 Merrill Street, Indianapolis, IN 46285, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbrc.2008.04.004DOI Listing
June 2008

A novel splicing variant of proprotein convertase subtilisin/kexin type 9.

DNA Cell Biol 2008 Apr;27(4):183-9

Lilly Research Laboratories, Eli Lilly & Company, Indianapolis, Indiana 46285, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/dna.2007.0667DOI Listing
April 2008

An apolipoprotein A-I mimetic dose-dependently increases the formation of prebeta1 HDL in human plasma.

J Lipid Res 2008 Mar 3;49(3):581-7. Epub 2007 Dec 3.

Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1194/jlr.M700385-JLR200DOI Listing
March 2008

Effect of apolipoprotein A-V on plasma triglyceride, lipoprotein size, and composition in genetically engineered mice.

J Lipid Res 2008 Mar 3;49(3):572-80. Epub 2007 Dec 3.

Center for Prevention of Obesity, Diabetes, and Cardiovascular Disease, Children's Hospital Oakland Research Institute, Oakland, CA 94609, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1194/jlr.M700281-JLR200DOI Listing
March 2008

Identification and characterization of a major liver lysophosphatidylcholine acyltransferase.

J Biol Chem 2008 Mar 14;283(13):8258-65. Epub 2008 Jan 14.

Lilly Research Laboratories, Eli Lilly & Company, Indianapolis, IN 46285, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M710422200DOI Listing
March 2008

Atorvastatin increases human serum levels of proprotein convertase subtilisin/kexin type 9.

J Lipid Res 2008 Feb 21;49(2):394-8. Epub 2007 Nov 21.

Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1194/jlr.M700437-JLR200DOI Listing
February 2008

Serum proprotein convertase subtilisin kexin type 9 is correlated directly with serum LDL cholesterol.

Clin Chem 2007 Oct 16;53(10):1814-9. Epub 2007 Aug 16.

Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1373/clinchem.2007.091280DOI Listing
October 2007

An Affinity Capture Elution (ACE) assay for detection of anti-drug antibody to monoclonal antibody therapeutics in the presence of high levels of drug.

J Immunol Methods 2007 Oct 27;327(1-2):10-7. Epub 2007 Jul 27.

Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jim.2007.07.004DOI Listing
October 2007

Relationship of apolipoprotein A5 and apolipoprotein C3 levels to serum triglycerides in patients with type 2 diabetes.

Clin Chim Acta 2007 Mar 24;378(1-2):154-8. Epub 2006 Nov 24.

Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cca.2006.11.009DOI Listing
March 2007

Alloxan is an inhibitor of O-GlcNAc-selective N-acetyl-beta-D-glucosaminidase.

Biochem Biophys Res Commun 2006 Dec 6;350(4):1038-43. Epub 2006 Oct 6.

Eli Lilly and Company, Indianapolis, IN 46285, USA.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S0006291X0602206
Publisher Site
http://dx.doi.org/10.1016/j.bbrc.2006.09.155DOI Listing
December 2006

Optimization of analytical and pre-analytical variables associated with an ex vivo cytokine secretion assay.

J Pharm Biomed Anal 2006 Apr;41(1):189-95

Laboratory for Experimental Medicine, Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN 46285, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jpba.2005.10.013DOI Listing
April 2006

Definitive N-terminal protein sequence and further characterization of the novel apolipoprotein A5 in human serum.

Clin Chem 2006 Mar;52(3):514-7

Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1373/clinchem.2005.061374DOI Listing
March 2006

Effect of double antigen bridging immunoassay format on antigen coating concentration dependence and implications for designing immunogenicity assays for monoclonal antibodies.

J Pharm Biomed Anal 2005 Sep;39(3-4):685-90

Lilly Research Laboratories, Eli Lilly and company, Building 88-313, Eli Lilly Corporate Center, Indianapolis, IN 46285, USA.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S073170850500279
Publisher Site
http://dx.doi.org/10.1016/j.jpba.2005.03.037DOI Listing
September 2005

Administration of a PPARalpha agonist increases serum apolipoprotein A-V levels and the apolipoprotein A-V/apolipoprotein C-III ratio.

J Lipid Res 2005 Aug 16;46(8):1591-5. Epub 2005 May 16.

Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1194/jlr.C500010-JLR200DOI Listing
August 2005

Differential reactivity of anti-primate and anti-human secondary antibodies against human and monkey immunoglobulins: implications for determining the sensitivity of immunogenicity assays.

J Immunol Methods 2005 Aug;303(1-2):76-80

Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jim.2005.06.003DOI Listing
August 2005

Glucose stimulates the association of Crk with p130Cas in pancreatic beta cells.

Pancreas 2004 Nov;29(4):e100-5

Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/00006676-200411000-00163DOI Listing
November 2004

Glucose stimulates the tyrosine phosphorylation of Crk-associated substrate in pancreatic beta-cells.

J Biol Chem 2003 Jul 12;278(30):28116-22. Epub 2003 May 12.

Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M212899200DOI Listing
July 2003

The role of O-linked protein glycosylation in beta-cell dysfunction.

Int J Mol Med 2002 Nov;10(5):535-9

Department of Diagnostic and Experimental Medicine, Eli Lilly and Company, Indianapolis, IN 46285, USA.

View Article

Download full-text PDF

Source
November 2002

Streptozotocin, an O-GlcNAcase inhibitor, blunts insulin and growth hormone secretion.

Mol Cell Endocrinol 2002 Aug;194(1-2):135-46

Department of Medicine/Endocrinology, Cell Biology, University of Alabama at Birmingham, 1808 7th Avenue South, Rm 756, Birmingham, AL 35294, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0303-7207(02)00155-7DOI Listing
August 2002

Comparison of non-diglyceride- and diglyceride-based assays for pancreatic lipase activity.

J Clin Lab Anal 2002 ;16(1):52-5

Department of Pathology, University of Alabama-Birmingham, Birmingham, Alabama, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcla.2023DOI Listing
April 2002

Alloxan is an inhibitor of the enzyme O-linked N-acetylglucosamine transferase.

Biochem Biophys Res Commun 2002 Apr;293(1):207-12

Department of Diagnostic and Experimental Medicine, Eli Lilly and Company, Indianapolis, IN 46285, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S0006-291X(02)00200-0DOI Listing
April 2002