Publications by authors named "Robert J Coffey"

188Publications

Molecular Imaging of Inflammation in Osteoarthritis Using a Water-Soluble Fluorocoxib.

ACS Med Chem Lett 2020 Oct 24;11(10):1875-1880. Epub 2020 Feb 24.

A. B. Hancock, Jr. Memorial Laboratory for Cancer Research, Departments of Biochemistry, Chemistry, and Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, United States.

View Article and Find Full Text PDF
October 2020

Rab13 regulates sEV secretion in mutant KRAS colorectal cancer cells.

Sci Rep 2020 09 25;10(1):15804. Epub 2020 Sep 25.

Department of Biological Sciences, Vanderbilt University Medical Center, Nashville, TN, 37235, USA.

View Article and Find Full Text PDF
September 2020

Succinate Produced by Intestinal Microbes Promotes Specification of Tuft Cells to Suppress Ileal Inflammation.

Gastroenterology 2020 Dec 21;159(6):2101-2115.e5. Epub 2020 Aug 21.

Epithelial Biology Center, Vanderbilt University Medical Center, Nashville, Tennessee; Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, Tennessee; Program in Chemical and Physical Biology, Vanderbilt University, Nashville, Tennessee; Center for Mucosal Inflammation and Cancer, Vanderbilt University Medical Center, Nashville, Tennessee; Center for Quantitative Sciences, Vanderbilt University School of Medicine, Nashville, Tennessee. Electronic address:

View Article and Find Full Text PDF
December 2020

Combined blockade of EGFR and glutamine metabolism in preclinical models of colorectal cancer.

Transl Oncol 2020 Oct 8;13(10):100828. Epub 2020 Jul 8.

Vanderbilt Center for Molecular Probes, Vanderbilt University Medical Center, 1161 21(st) Avenue South, Medical Center North, R0102, Nashville, TN 37232, United States; Vanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, 1161 21st Avenue South, Medical Center North, R0102, Nashville, TN 37232, United States; Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, 1161 21st Avenue South, Medical Center North, Nashville, TN 37232, United States; Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, 2220 Pierce Avenue, Nashville, TN 37232, United States. Electronic address:

View Article and Find Full Text PDF
October 2020

KRAS Mutation-Responsive miR-139-5p inhibits Colorectal Cancer Progression and is repressed by Wnt Signaling.

Theranostics 2020 5;10(16):7335-7350. Epub 2020 Jun 5.

State Key Laboratory of Cancer Biology and National Clinical Research Center for Digestive Diseases, Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, Shaanxi 710032, China.

View Article and Find Full Text PDF
June 2020

Identification and Characterization of Unique Neutralizing Antibodies to Mouse EGF Receptor.

Gastroenterology 2020 04 19;158(5):1500-1502. Epub 2019 Dec 19.

Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, Tennessee. Electronic address:

View Article and Find Full Text PDF
April 2020

Heterogeneity within Stratified Epithelial Stem Cell Populations Maintains the Oral Mucosa in Response to Physiological Stress.

Cell Stem Cell 2019 12;25(6):814-829.e6

Department of Pathology & Laboratory Medicine, the University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA; Lineberger Comprehensive Cancer Center, the University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address:

View Article and Find Full Text PDF
December 2019

miR-302a Inhibits Metastasis and Cetuximab Resistance in Colorectal Cancer by Targeting NFIB and CD44.

Theranostics 2019 22;9(26):8409-8425. Epub 2019 Oct 22.

State Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an 710032, China.

View Article and Find Full Text PDF
September 2020

scRNABatchQC: multi-samples quality control for single cell RNA-seq data.

Bioinformatics 2019 12;35(24):5306-5308

Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, TN, USA.

View Article and Find Full Text PDF
December 2019

Transfer of Functional Cargo in Exomeres.

Cell Rep 2019 04 4;27(3):940-954.e6. Epub 2019 Apr 4.

Department of Medicine/Gastroenterology and Epithelial Biology Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Cell and Developmental Biology, Vanderbilt University, Nashville, TN 37235, USA; Department of Veterans Affairs Medical Center, Nashville, Vanderbilt University, TN 37212, USA. Electronic address:

View Article and Find Full Text PDF
April 2019

Reassessment of Exosome Composition.

Cell 2019 04;177(2):428-445.e18

Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA; Veterans Affairs Medical Center, Nashville, TN 37232, USA. Electronic address:

View Article and Find Full Text PDF
April 2019

Linking ALDH1 and retinoic acid signaling.

Oncotarget 2019 Feb 8;10(12):1226-1227. Epub 2019 Feb 8.

Vanderbilt University Medical Center, Nashville, TN, USA.

View Article and Find Full Text PDF
February 2019