Publications



Serum-based tracking of de novo initiated liver cancer progression reveals early immunoregulation and response to therapy.
J Hepatol 2015 Nov 2;63(5):1181-9. Epub 2015 Jul 2.
Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD 21702, United States. Electronic address:

Out-of-Sequence Signal 3 Paralyzes Primary CD4(+) T-Cell-Dependent Immunity.
Immunity 2015 Aug 28;43(2):240-50. Epub 2015 Jul 28.
Department of Dermatology, School of Medicine, University of California, Davis, Sacramento, CA 95817, USA; Department of Internal Medicine, School of Medicine, University of California, Davis, Sacramento, CA 95817, USA. Electronic address:


Tumor-induced CD11b(+) Gr-1(+) myeloid-derived suppressor cells exacerbate immune-mediated hepatitis in mice in a CD40-dependent manner.
Eur J Immunol 2015 Apr 23;45(4):1148-58. Epub 2015 Feb 23.
Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.

Adiposity induces lethal cytokine storm after systemic administration of stimulatory immunotherapy regimens in aged mice.
J Exp Med 2014 Nov 3;211(12):2373-83. Epub 2014 Nov 3.
Department of Dermatology, Department of Pathology and Laboratory Medicine, Department of Radiation Oncology, and Department of Dermatology and Internal Medicine, University of California, Davis, Sacramento, CA 95817

Bystander activation and anti-tumor effects of CD8+ T cells following Interleukin-2 based immunotherapy is independent of CD4+ T cell help.
PLoS One 2014 13;9(8):e102709. Epub 2014 Aug 13.
Department of Dermatology, School of Medicine, University of California Davis, Sacramento, California, United States of America; Department of Internal Medicine, School of Medicine, University of California, Davis, Sacramento, California, United States of America.

Aging predisposes to acute inflammatory induced pathology after tumor immunotherapy.
J Exp Med 2013 Oct 30;210(11):2223-37. Epub 2013 Sep 30.
Department of Microbiology & Immunology and 2 Department of Physiology and Cell Biology, University of Nevada-Reno School of Medicine, Reno, NV 89557.



Successful immunotherapy with IL-2/anti-CD40 induces the chemokine-mediated mitigation of an immunosuppressive tumor microenvironment.
Proc Natl Acad Sci U S A 2009 Nov 5;106(46):19455-60. Epub 2009 Nov 5.
Laboratory of Experimental Immunology, Cancer and Inflammation Program, NCI Frederick, Frederick, MD 21702, USA.




Nitric oxide, a mediator of inflammation, suppresses tumorigenesis.
Cancer Res 2004 Oct;64(19):6849-53
Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892-4255, USA.

Activation of cutaneous protein kinase C alpha induces keratinocyte apoptosis and intraepidermal inflammation by independent signaling pathways.
J Immunol 2003 Sep;171(5):2703-13
Laboratories of Cellular Carcinogenesis and Tumor Promotion, Center for Cancer Research, National Cancer Institute/NIH, 37 Convent Drive, Bethesda, MD 20892, USA.


Tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis is an important endogenous mechanism for resistance to liver metastases in murine renal cancer.
Cancer Res 2003 Jan;63(1):207-13
Laboratory of Experimental Immunology, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, Maryland 21702-1201, USA.


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