Robert G Will

Robert G Will

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Robert G Will

Robert G Will

Publications by authors named "Robert G Will"

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Public health risks from subclinical variant CJD.

PLoS Pathog 2017 11 30;13(11):e1006642. Epub 2017 Nov 30.

The Roslin Institute & R(D)SVS, University of Edinburgh, Easter Bush, United Kingdom.

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http://dx.doi.org/10.1371/journal.ppat.1006642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708614PMC
November 2017

Sporadic and Infectious Human Prion Diseases.

Cold Spring Harb Perspect Med 2017 Jan 3;7(1). Epub 2017 Jan 3.

National Creutzfeldt-Jakob Disease Research and Surveillance Unit, Centre for Clinical Brain Sciences, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, United Kingdom.

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http://perspectivesinmedicine.cshlp.org/lookup/doi/10.1101/c
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http://dx.doi.org/10.1101/cshperspect.a024364DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204333PMC
January 2017

The end of the BSE saga: do we still need surveillance for human prion diseases?

Swiss Med Wkly 2015 12;145:w14212. Epub 2015 Nov 12.

National CJD Research & Surveillance Unit, Western General Hospital, Edinburgh, UK.

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http://dx.doi.org/10.4414/smw.2015.14212DOI Listing
September 2016

Quantifying prion disease penetrance using large population control cohorts.

Sci Transl Med 2016 Jan;8(322):322ra9

Program in Medical and Population Genetics, Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA 02142, USA. Analytical and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1126/scitranslmed.aad5169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774245PMC
January 2016

Variant CJD. 18 years of research and surveillance.

Prion 2014 1;8(4):286-95. Epub 2014 Nov 1.

a The Roslin Institute and R(D)SVS ; University of Edinburgh; Easter Bush ; Midlothian , Scotland , UK.

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http://dx.doi.org/10.4161/pri.29237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601215PMC
October 2015

Prion infectivity in the spleen of a PRNP heterozygous individual with subclinical variant Creutzfeldt-Jakob disease.

Brain 2013 Apr 28;136(Pt 4):1139-45. Epub 2013 Feb 28.

National Creutzfeldt–Jakob Disease Research and Surveillance Unit, University of Edinburgh, Bryan Matthews Building, Western General Hospital, Crewe Road, Edinburgh, EH4 2XU, UK.

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https://academic.oup.com/brain/article-lookup/doi/10.1093/br
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http://dx.doi.org/10.1093/brain/awt032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613713PMC
April 2013

Sensitivity to biases of case-control studies on medical procedures, particularly surgery and blood transfusion, and risk of Creutzfeldt-Jakob disease.

Neuroepidemiology 2012 5;39(1):1-18. Epub 2012 Jul 5.

Department of Applied Epidemiology, National Centre for Epidemiology and Consortium for Biomedical Research in Neurodegenerative Diseases, Carlos III Institute of Health, Madrid, Spain.

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http://dx.doi.org/10.1159/000339318DOI Listing
December 2012

Genome-wide study links MTMR7 gene to variant Creutzfeldt-Jakob risk.

Neurobiol Aging 2012 Jul 2;33(7):1487.e21-8. Epub 2011 Dec 2.

Neurology Department, University Hospital Marqués de Valdecilla, Fundación Marqués de Valdecilla (University of Cantabria) IFIMAV and Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas, Santander, Spain.

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http://dx.doi.org/10.1016/j.neurobiolaging.2011.10.011DOI Listing
July 2012

Is there evidence of vertical transmission of variant Creutzfeldt-Jakob disease?

J Neurol Neurosurg Psychiatry 2011 Jul 27;82(7):729-31. Epub 2009 Apr 27.

National CreutzfeldteJakob Disease Surveillance Unit, Western General Hospital, Edinburgh, UK.

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http://jnnp.bmj.com/content/early/2009/04/27/jnnp.2009.17214
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http://jnnp.bmj.com/cgi/doi/10.1136/jnnp.2009.172148
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http://dx.doi.org/10.1136/jnnp.2009.172148DOI Listing
July 2011

Clinical aspects of variant Creutzfeldt-Jakob disease.

Handb Clin Neurol 2008 ;89:765-78

National CJD Surveillance Unit, Western General Hospital, Edinburgh, UK.

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http://dx.doi.org/10.1016/S0072-9752(07)01267-5DOI Listing
December 2010

Disinfection and sterilization of prion-contaminated medical instruments.

Infect Control Hosp Epidemiol 2010 Dec;31(12):1304-6; author reply 1306-8

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http://dx.doi.org/10.1086/657579DOI Listing
December 2010

Defining sporadic Creutzfeldt-Jakob disease strains and their transmission properties.

Proc Natl Acad Sci U S A 2010 Jun 14;107(26):12005-10. Epub 2010 Jun 14.

National Creutzfeldt-Jakob Disease Surveillance Unit, Western General Hospital, University of Edinburgh, Edinburgh EH4 2XU, United Kingdom.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1004688107
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http://dx.doi.org/10.1073/pnas.1004688107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900653PMC
June 2010

PRNP variation in UK sporadic and variant Creutzfeldt Jakob disease highlights genetic risk factors and a novel non-synonymous polymorphism.

BMC Med Genet 2009 Dec 26;10:146. Epub 2009 Dec 26.

National CJD Surveillance Unit, University of Edinburgh, Bryan Matthews Building, Western General Hospital, Crewe Road, Edinburgh, EH4 2XU, UK.

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http://dx.doi.org/10.1186/1471-2350-10-146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806268PMC
December 2009

No major change in vCJD agent strain after secondary transmission via blood transfusion.

PLoS One 2008 Aug 6;3(8):e2878. Epub 2008 Aug 6.

National CJD Surveillance Unit, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0002878PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2478718PMC
August 2008

Risk factors for sporadic Creutzfeldt-Jakob disease.

Ann Neurol 2008 Mar;63(3):347-54

National Creutzfeldt-Jakob Disease Surveillance Unit, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1002/ana.21294DOI Listing
March 2008

Is there the potential for an epidemic of variant Creutzfeldt-Jakob disease via blood transfusion in the UK?

J R Soc Interface 2007 Aug;4(15):675-84

Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK.

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http://dx.doi.org/10.1098/rsif.2007.0216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2373392PMC
August 2007

Source of variant Creutzfeldt-Jakob disease outside United Kingdom.

Emerg Infect Dis 2007 Aug;13(8):1166-9

Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands.

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http://wwwnc.cdc.gov/eid/article/13/8/07-0178_article.htm
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828088PMC
http://dx.doi.org/10.3201/eid1308.070178DOI Listing
August 2007

Quantification of Peyer's patches in Cheviot sheep for future scrapie pathogenesis studies.

Vet Immunol Immunopathol 2007 Apr 2;116(3-4):163-71. Epub 2007 Feb 2.

Centre for Infectious Diseases, University of Edinburgh, Ashworth Laboratories, King's Buildings, West Mains Road, Edinburgh EH9 3JF, Scotland, UK.

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http://dx.doi.org/10.1016/j.vetimm.2007.01.017DOI Listing
April 2007

Factors determining the potential for onward transmission of variant Creutzfeldt-Jakob disease via surgical instruments.

J R Soc Interface 2006 Dec;3(11):757-66

Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK.

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http://rsif.royalsocietypublishing.org/cgi/doi/10.1098/rsif.
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http://dx.doi.org/10.1098/rsif.2006.0142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885367PMC
December 2006

Application of an immunocapillary electrophoresis assay to the detection of abnormal prion protein in brain, spleen and blood specimens from patients with variant Creutzfeldt-Jakob disease.

J Gen Virol 2006 Oct;87(Pt 10):3119-24

National CJD Surveillance Unit, School of Molecular and Clinical Medicine, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK.

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http://dx.doi.org/10.1099/vir.0.81935-0DOI Listing
October 2006

Risk factors for variant Creutzfeldt-Jakob disease: a case-control study.

Ann Neurol 2006 Jan;59(1):111-20

National Creutzfeldt-Jakob Disease Surveillance Unit, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK.

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http://dx.doi.org/10.1002/ana.20708DOI Listing
January 2006

Prion protein heterogeneity in sporadic but not variant Creutzfeldt-Jakob disease: UK cases 1991-2002.

Ann Neurol 2004 Jun;55(6):851-9

National Creutzfeldt-Jakob Disease Surveillance Unit and Division of Pathology, School of Molecular and Clinical Medicine, University of Edinburgh, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1002/ana.20127DOI Listing
June 2004

Creutzfeldt-Jakob disease and urinary gonadotrophins.

Hum Reprod 2004 May;19(5):1236-7

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http://dx.doi.org/10.1093/humrep/deh175DOI Listing
May 2004

Acquired prion disease: iatrogenic CJD, variant CJD, kuru.

Authors:
Robert G Will

Br Med Bull 2003 ;66:255-65

National CJD Surveillance Unit, Department of Clinical Neuroscience, Western General Hospital, Edinburgh, UK.

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http://dx.doi.org/10.1093/bmb/66.1.255DOI Listing
November 2003

Diagnosing variant Creutzfeldt-Jakob disease with the pulvinar sign: MR imaging findings in 86 neuropathologically confirmed cases.

AJNR Am J Neuroradiol 2003 Sep;24(8):1560-9

Department of Neuroradiology, Western General Hospital, Edinburgh, Scotland.

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September 2003

The geographical distribution of variant Creutzfeldt-Jakob disease cases in the UK: what can we learn from it?

Stat Methods Med Res 2003 Jun;12(3):235-46

Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK.

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http://dx.doi.org/10.1191/0962280203sm332raDOI Listing
June 2003

MHC typing in variant Creutzfeldt-Jakob disease.

Lancet 2003 Feb;361(9356):487-9

Centre for Amyloidosis and Acute Phase Proteins, Department of Medicine, Royal Free and University College Medical School, Rowland Hill Street, NW3 2PF, London, UK.

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http://dx.doi.org/10.1016/S0140-6736(03)12455-5DOI Listing
February 2003

PRNP contains both intronic and upstream regulatory regions that may influence susceptibility to Creutzfeldt-Jakob Disease.

Gene 2002 Apr;288(1-2):139-46

Neuropathogenesis Unit, Institute for Animal Health, West Mains Road, Edinburgh EH9 3JF, UK.

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http://dx.doi.org/10.1016/s0378-1119(02)00466-3DOI Listing
April 2002

Variant Creutzfeldt-Jakob disease: costs borne by families.

Health Soc Care Community 2002 Mar;10(2):91-8

Department of Community Health Sciences - General Practice, University of Edinburgh, UK.

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March 2002

Creutzfeldt-Jakob disease in elderly people.

Age Ageing 2002 Jan;31(1):7-10

National Creutzfeldt-Jakob Disease Surveillance Unit, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK.

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http://dx.doi.org/10.1093/ageing/31.1.7DOI Listing
January 2002

Predicting the size of the vCJD epidemic in France.

C R Biol 2002 Jan;325(1):33-6

Institut national de la santé et de la recherche médicale, unité 360, hôpital de la Salpêtrière, 75651 Paris, France.

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January 2002