Robert D Gray

Robert D Gray

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Robert D Gray

Robert D Gray

Publications by authors named "Robert D Gray"

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Profusion of G-quadruplexes on both subunits of metazoan ribosomes.

PLoS One 2019 13;14(12):e0226177. Epub 2019 Dec 13.

Center for the Origin of Life, Georgia Institute of Technology, Atlanta, Georgia, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0226177PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910669PMC
April 2020

Human POT1 unfolds G-quadruplexes by conformational selection.

Nucleic Acids Res 2020 Mar 31. Epub 2020 Mar 31.

James Graham Brown Cancer Center, University of Louisville, 505 S. Hancock St., Louisville, KY 40202, USA.

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http://dx.doi.org/10.1093/nar/gkaa202DOI Listing
March 2020

The hTERT core promoter forms three parallel G-quadruplexes.

Nucleic Acids Res 2020 Feb 21. Epub 2020 Feb 21.

Department of Biochemistry & Molecular Genetics, University of Louisville, Louisville, KY 40202, USA.

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http://dx.doi.org/10.1093/nar/gkaa107DOI Listing
February 2020

Recombinant expression and purification of AF1q and its interaction with T-cell Factor 7.

Protein Expr Purif 2020 01 18;165:105499. Epub 2019 Sep 18.

Department of Medicine, James Graham Brown Cancer Center, University of Louisville, 505 S. Hancock St., Louisville, KY, 40202, USA. Electronic address:

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http://dx.doi.org/10.1016/j.pep.2019.105499DOI Listing
January 2020

Nanoscale polarization of the entry fusion complex of vaccinia virus drives efficient fusion.

Nat Microbiol 2019 10 8;4(10):1636-1644. Epub 2019 Jul 8.

MRC Laboratory for Molecular Cell Biology, University College London, London, UK.

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http://dx.doi.org/10.1038/s41564-019-0488-4DOI Listing
October 2019

Human cystic fibrosis monocyte derived macrophages display no defect in acidification of phagolysosomes when measured by optical nanosensors.

J Cyst Fibros 2019 Sep 6. Epub 2019 Sep 6.

Centre for Inflammation Research, The Queen's Medical Research Institute, 47 Little France Crescent, The University of Edinburgh, Edinburgh EH16 4TJ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jcf.2019.09.003DOI Listing
September 2019

Folding Landscape of a Parallel G-Quadruplex.

J Phys Chem Lett 2019 Mar 27;10(5):1146-1151. Epub 2019 Feb 27.

J. G. Brown Cancer Center , University of Louisville , 505 South Hancock Street , Louisville , Kentucky 40202 , United States.

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http://dx.doi.org/10.1021/acs.jpclett.9b00227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6455816PMC
March 2019

Putting a New Spin of G-Quadruplex Structure and Binding by Analytical Ultracentrifugation.

Methods Mol Biol 2019 ;2035:87-103

James Graham Brown Cancer Center, University of Louisville, Louisville, KY, USA.

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http://dx.doi.org/10.1007/978-1-4939-9666-7_5DOI Listing
January 2019

NETs in pneumonia: is just enough the right amount?

Authors:
Robert D Gray

Eur Respir J 2018 04 26;51(4). Epub 2018 Apr 26.

MRC Centre for Inflammation Research at the University of Edinburgh, Queen's Medical Research Institute, Edinburgh, UK

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http://dx.doi.org/10.1183/13993003.00619-2018DOI Listing
April 2018

Conformational profiling of a G-rich sequence within the c-KIT promoter.

Nucleic Acids Res 2017 Dec;45(22):13056-13067

Department of Pharmaceutical and Pharmacological Sciences, University of Padova, 35131 Padova, Italy.

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http://dx.doi.org/10.1093/nar/gkx983DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727440PMC
December 2017

Neutrophil extracellular traps and the dysfunctional innate immune response of cystic fibrosis lung disease: a review.

J Inflamm (Lond) 2017 28;14:29. Epub 2017 Dec 28.

MRC Centre for Inflammation Research, The Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh, EH16 4TJ UK.

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http://dx.doi.org/10.1186/s12950-017-0176-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745605PMC
December 2017

Monocyte derived macrophages from CF pigs exhibit increased inflammatory responses at birth.

J Cyst Fibros 2017 Jul 1;16(4):471-474. Epub 2017 Apr 1.

Department of Pediatrics, Pappajohn Biomedical Institute, Carver College of Medicine, University of Iowa, Iowa City, IA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jcf.2017.03.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515361PMC
July 2017

Biomarkers to monitor exacerbations in cystic fibrosis.

Expert Rev Respir Med 2017 04;11(4):255-257

c Airway Innate Immunity Research (AiiR) Group, Centre for Experimental Medicine , The Wellcome-Wolfson Building, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast , Northern Ireland.

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http://dx.doi.org/10.1080/17476348.2017.1307739DOI Listing
April 2017

Open-source Single-particle Analysis for Super-resolution Microscopy with VirusMapper.

J Vis Exp 2017 04 9(122). Epub 2017 Apr 9.

MRC Laboratory for Molecular Cell Biology, University College London; Department of Cell and Developmental Biology, University College London;

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http://dx.doi.org/10.3791/55471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564481PMC
April 2017

Characterization of Quadruplex DNA Structure by Circular Dichroism.

Curr Protoc Nucleic Acid Chem 2017 03 2;68:17.8.1-17.8.16. Epub 2017 Mar 2.

James Graham Brown Cancer Center, University of Louisville, Louisville, Kentucky.

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http://dx.doi.org/10.1002/cpnc.23DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334661PMC
March 2017

A Simple Fluorescence Assay for Quantification of Canine Neutrophil Extracellular Trap Release.

J Vis Exp 2016 11 21(117). Epub 2016 Nov 21.

Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University;

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http://dx.doi.org/10.3791/54726DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226257PMC
November 2016

A method to implement the reservoir-wave hypothesis using phase-contrast magnetic resonance imaging.

MethodsX 2016 25;3:508-512. Epub 2016 Aug 25.

Centre for Cardiovascular Imaging, Institute of Cardiovascular Science, University College London & Great Ormond Street Hospital for Children, NHS Foundation Trust, London, United Kingdom; Bristol Heart Institute, University of Bristol, Bristol, United Kingdom.

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http://dx.doi.org/10.1016/j.mex.2016.08.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156381PMC
August 2016

VirusMapper: open-source nanoscale mapping of viral architecture through super-resolution microscopy.

Sci Rep 2016 07 4;6:29132. Epub 2016 Jul 4.

MRC-Laboratory for Molecular Cell Biology. University College London, Gower Street, London, WC1E 6BT, United Kingdom.

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http://dx.doi.org/10.1038/srep29132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931586PMC
July 2016

An improved model for the hTERT promoter quadruplex.

PLoS One 2014 19;9(12):e115580. Epub 2014 Dec 19.

James Graham Brown Cancer Center, Department of Medicine, University of Louisville, Louisville, Kentucky, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0115580PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272262PMC
December 2015

NETs and CF Lung Disease: Current Status and Future Prospects.

Antibiotics (Basel) 2015 Jan 15;4(1):62-75. Epub 2015 Jan 15.

Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.

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http://dx.doi.org/10.3390/antibiotics4010062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790323PMC
January 2015

Invertebrate extracellular phagocyte traps show that chromatin is an ancient defence weapon.

Nat Commun 2014 Aug 13;5:4627. Epub 2014 Aug 13.

Scottish Oceans Institute, School of Biology, University of St Andrews, St Andrews, Scotland KY16 8LB, UK.

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http://dx.doi.org/10.1038/ncomms5627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143918PMC
August 2014

Folding and unfolding pathways of the human telomeric G-quadruplex.

J Mol Biol 2014 Apr 31;426(8):1629-50. Epub 2014 Jan 31.

James Graham Brown Cancer Center, University of Louisville, Louisville, KY 40202, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2014.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969789PMC
April 2014

Polyethylene glycol binding alters human telomere G-quadruplex structure by conformational selection.

Nucleic Acids Res 2013 Sep 26;41(16):7934-46. Epub 2013 Jun 26.

James Graham Brown Cancer Center, University of Louisville, 505 S. Hancock, Louisville, KY, 40202.

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http://dx.doi.org/10.1093/nar/gkt440DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763525PMC
September 2013

Activation of conventional protein kinase C (PKC) is critical in the generation of human neutrophil extracellular traps.

J Inflamm (Lond) 2013 Mar 21;10(1):12. Epub 2013 Mar 21.

MRC Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh Medical School, 47 Little France Crescent, Edinburgh, Scotland, UK.

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http://dx.doi.org/10.1186/1476-9255-10-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643828PMC
March 2013

Populated intermediates in the thermal unfolding of the human telomeric quadruplex.

J Am Chem Soc 2012 Oct 27;134(40):16834-44. Epub 2012 Sep 27.

James Graham Brown Cancer Center, University of Louisville, Louisville, Kentucky 40202, USA.

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http://dx.doi.org/10.1021/ja307543zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477705PMC
October 2012

Systemic elastin degradation in chronic obstructive pulmonary disease.

Thorax 2012 Jul 28;67(7):606-12. Epub 2012 Feb 28.

ELEGI Colt Laboratory, Queen's Medical Research Institute, The University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK.

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http://dx.doi.org/10.1136/thoraxjnl-2011-200949DOI Listing
July 2012

Isothermal folding of G-quadruplexes.

Methods 2012 May 16;57(1):47-55. Epub 2012 Apr 16.

James Graham Brown Cancer Center, University of Louisville, 505 S. Hancock St., Louisville, KY 40202, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S10462023120009
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http://dx.doi.org/10.1016/j.ymeth.2012.04.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407330PMC
May 2012

Differential global gene expression in cystic fibrosis nasal and bronchial epithelium.

Genomics 2011 Nov 2;98(5):327-36. Epub 2011 Jul 2.

Medical Genetics Section, Molecular Medicine Centre, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, UK.

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http://dx.doi.org/10.1016/j.ygeno.2011.06.008DOI Listing
November 2011

Linkage of cation binding and folding in human telomeric quadruplex DNA.

Biophys Chem 2011 Nov 28;159(1):205-9. Epub 2011 Jun 28.

James Graham Brown Cancer Center, University of Louisville, Louisville, KY 40202, United States.

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https://linkinghub.elsevier.com/retrieve/pii/S03014622110021
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http://dx.doi.org/10.1016/j.bpc.2011.06.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166971PMC
November 2011

Analysis of multidimensional G-quadruplex melting curves.

Curr Protoc Nucleic Acid Chem 2011 Jun;Chapter 17:Unit17.4

James Graham Brown Cancer Center, University of Louisville, Louisville, Kentucky, USA.

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http://dx.doi.org/10.1002/0471142700.nc1704s45DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398426PMC
June 2011

Sputum trace metals are biomarkers of inflammatory and suppurative lung disease.

Chest 2010 Mar 3;137(3):635-41. Epub 2009 Oct 3.

School of Molecular and Clinical Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland.

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http://dx.doi.org/10.1378/chest.09-1047DOI Listing
March 2010

2-aminopurine as a probe for quadruplex loop structures.

Methods Mol Biol 2010 ;608:121-36

James Graham Brown Cancer Center, University of Louisville, Louisville, KY, USA.

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http://dx.doi.org/10.1007/978-1-59745-363-9_8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008626PMC
February 2010

Characterization of a K+-induced conformational switch in a human telomeric DNA oligonucleotide using 2-aminopurine fluorescence.

Biochemistry 2010 Jan;49(1):179-94

James Graham Brown Cancer Center, University of Louisville, Louisville, Kentucky 40202, USA.

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http://dx.doi.org/10.1021/bi901357rDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2803354PMC
January 2010

Energetics and kinetics of a conformational switch in G-quadruplex DNA.

J Phys Chem B 2009 Mar;113(9):2676-83

James Graham Brown Cancer Center, University of Louisville, 529 South Jackson Street, Louisville, Kentucky 40202, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2772118PMC
http://dx.doi.org/10.1021/jp809578fDOI Listing
March 2009

Ligand-induced nuclear translocation of S1P(1) receptors mediates Cyr61 and CTGF transcription in endothelial cells.

Histochem Cell Biol 2009 Feb 21;131(2):239-49. Epub 2008 Oct 21.

Department of Microbiology and Immunology, Gheens Center on Aging, University of Louisville Health Sciences Center, Louisville, KY 40202, USA.

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http://dx.doi.org/10.1007/s00418-008-0521-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861785PMC
February 2009

Stability and kinetics of G-quadruplex structures.

Nucleic Acids Res 2008 Oct 21;36(17):5482-515. Epub 2008 Aug 21.

Structural Biology Program, JG Brown Cancer Center, University of Louisville, KY 40202, USA.

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http://dx.doi.org/10.1093/nar/gkn517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553573PMC
October 2008

Biomarkers for cystic fibrosis lung disease: application of SELDI-TOF mass spectrometry to BAL fluid.

J Cyst Fibros 2008 Sep 1;7(5):352-8. Epub 2008 Feb 1.

School of Molecular and Clinical Medicine, University of Edinburgh, EH4 2XU, United Kingdom.

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http://dx.doi.org/10.1016/j.jcf.2007.12.005DOI Listing
September 2008

Sputum proteomics in inflammatory and suppurative respiratory diseases.

Am J Respir Crit Care Med 2008 Sep 19;178(5):444-52. Epub 2008 Jun 19.

School of Molecular and Clinical Medicine, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1164/rccm.200703-409OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2643212PMC
September 2008

PEDF from mouse mesenchymal stem cell secretome attracts fibroblasts.

J Cell Biochem 2008 Aug;104(5):1793-802

Gheens Center on Aging, University of Louisville School of Medicine, Louisville, Kentucky 40202, USA.

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http://dx.doi.org/10.1002/jcb.21748DOI Listing
August 2008

Kinetics and mechanism of K+- and Na+-induced folding of models of human telomeric DNA into G-quadruplex structures.

Nucleic Acids Res 2008 Jul 21;36(12):4191-203. Epub 2008 Jun 21.

James Graham Brown Cancer Center, University of Louisville, 529 S. Jackson Street, Louisville, KY 40202, USA.

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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gkn379DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2475619PMC
July 2008

NMR structure note: alkaline proteinase inhibitor APRin from Pseudomonas aeruginosa.

J Biomol NMR 2008 Mar 24;40(3):213-7. Epub 2008 Jan 24.

J.G. Graham Brown Cancer Center, University of Louisville, Louisville, KY 40202, USA.

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http://dx.doi.org/10.1007/s10858-008-9218-6DOI Listing
March 2008

Decongestant effects of nasal xylometazoline and mometasone furoate in persistent allergic rhinitis.

Rhinology 2005 Dec;43(4):291-5

Asthma and Allergy Research Group, Ninewells Hospital and Medical School, University of Dundee, Dundee, Scotland, United Kingdom.

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December 2005

Contribution of a single-turn alpha-helix to the conformational stability and activity of the alkaline proteinase inhibitor of Pseudomonas aeruginosa.

Biochemistry 2005 Feb;44(7):2469-77

Department of Biochemistry & Molecular Biology, James Graham Brown Cancer Center, University of Louisville School of Medicine, Louisville, Kentucky 40292, USA.

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http://dx.doi.org/10.1021/bi048287qDOI Listing
February 2005

Single and short-term dosing effects of levocetirizine on adenosine monophosphate bronchoprovocation in atopic asthma.

Br J Clin Pharmacol 2004 Jul;58(1):34-9

Asthma & Allergy Research Group, Department of Clinical Pharmacology, Ninewells Hospital & Medical School, University of Dundee, Dundee DD1 9SY, Scotland, UK.

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http://dx.doi.org/10.1111/j.1365-2125.2004.02110.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1884543PMC
July 2004

Effects of butterbur treatment in intermittent allergic rhinitis: a placebo-controlled evaluation.

Ann Allergy Asthma Immunol 2004 Jul;93(1):56-60

Asthma & Allergy Research Group, Ninewells Hospital & Medical School, University of Dundee, Dundee, Scotland.

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http://dx.doi.org/10.1016/S1081-1206(10)61447-0DOI Listing
July 2004

Alkaline proteinase inhibitor of Pseudomonas aeruginosa: a mutational and molecular dynamics study of the role of N-terminal residues in the inhibition of Pseudomonas alkaline proteinase.

J Biol Chem 2003 Jul 21;278(28):25952-7. Epub 2003 Apr 21.

Department of Biochemistry, University of Louisville School of Medicine, Louisville, Kentucky 40292, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M212691200
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http://dx.doi.org/10.1074/jbc.M212691200DOI Listing
July 2003

The GP's role in allergic rhinitis.

Practitioner 2003 May;247(1646):418-23

Asthma and Allergy Research Group, Department of Clinical Pharmacology, Ninewells Hospital and Medical School, University of Dundee, Dundee.

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May 2003

Chronic cough.

BMJ 2003 Feb;326(7383):261

Chest Clinic C, Aberdeen Royal Infirmary, Foresterhill, Aberdeen AB252ZN.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC140767PMC
http://dx.doi.org/10.1136/bmj.326.7383.261DOI Listing
February 2003

Combined mediator blockade or topical corticosteroids for seasonal allergic rhinitis.

J Allergy Clin Immunol 2002 Dec;110(6):939; author reply 940

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http://dx.doi.org/10.1067/mai.2002.129120DOI Listing
December 2002