Publications by authors named "Robert D Gerard"

52 Publications

PDZK1 prevents neointima formation via suppression of breakpoint cluster region kinase in vascular smooth muscle.

PLoS One 2015 17;10(4):e0124494. Epub 2015 Apr 17.

Center for Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.

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April 2016

The acetate/ACSS2 switch regulates HIF-2 stress signaling in the tumor cell microenvironment.

PLoS One 2015 17;10(2):e0116515. Epub 2015 Feb 17.

Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America; Department of Medicine, Veterans Affairs North Texas Health Care System, Dallas, Texas, United States of America.

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December 2015

Genetic variants of ApoE and ApoER2 differentially modulate endothelial function.

Proc Natl Acad Sci U S A 2014 Sep 2;111(37):13493-8. Epub 2014 Sep 2.

Center for Pulmonary and Vascular Biology, Department of Pediatrics, and

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September 2014

An acetate switch regulates stress erythropoiesis.

Nat Med 2014 Sep 10;20(9):1018-26. Epub 2014 Aug 10.

1] Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA. [2] Department of Medicine, VA North Texas Health Care System, Dallas, Texas, USA. [3].

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September 2014

TALEN-mediated somatic mutagenesis in murine models of cancer.

Cancer Res 2014 Sep 28;74(18):5311-21. Epub 2014 Jul 28.

Department of Pediatrics, Children's Research Institute, University of Texas Southwestern Medical Center, Dallas, Texas. Department of Internal Medicine, Children's Research Institute, University of Texas Southwestern Medical Center, Dallas, Texas.

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September 2014

Cytoglobin modulates myogenic progenitor cell viability and muscle regeneration.

Proc Natl Acad Sci U S A 2014 Jan 23;111(1):E129-38. Epub 2013 Dec 23.

Departments of Internal Medicine, Molecular Biology, and Pathology, the Donald W. Reynolds Cardiovascular Clinical Research Center, and the Heart Failure, Ventricular Assist Device and Heart Transplant Program, University of Texas Southwestern Medical Center, Dallas, TX 75390.

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January 2014

Metabolic hormone FGF21 is induced in ground squirrels during hibernation but its overexpression is not sufficient to cause torpor.

PLoS One 2013 2;8(1):e53574. Epub 2013 Jan 2.

Department of Biology, University of Minnesota Duluth, Duluth, Minnesota, United States of America.

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August 2013

C/EBP transcription factors mediate epicardial activation during heart development and injury.

Science 2012 Dec 15;338(6114):1599-603. Epub 2012 Nov 15.

Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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December 2012

Nuclear receptors HNF4α and LRH-1 cooperate in regulating Cyp7a1 in vivo.

J Biol Chem 2012 Nov 4;287(49):41334-41. Epub 2012 Oct 4.

Department of Pharmacology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390, USA.

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November 2012

Scavenger receptor class B type I is a plasma membrane cholesterol sensor.

Circ Res 2013 Jan 28;112(1):140-51. Epub 2012 Sep 28.

Department of Pediatrics, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390, USA.

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January 2013

The microRNA (miR)-199a/214 cluster mediates opposing effects of progesterone and estrogen on uterine contractility during pregnancy and labor.

Mol Endocrinol 2012 Nov 12;26(11):1857-67. Epub 2012 Sep 12.

Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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November 2012

Foxk1 promotes cell proliferation and represses myogenic differentiation by regulating Foxo4 and Mef2.

J Cell Sci 2012 Nov 6;125(Pt 22):5329-37. Epub 2012 Sep 6.

Lillehei Heart Institute, University of Minnesota-Twin Cities, Minneapolis, MN 55455, USA.

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November 2012

The acetylase/deacetylase couple CREB-binding protein/Sirtuin 1 controls hypoxia-inducible factor 2 signaling.

J Biol Chem 2012 Aug 17;287(36):30800-11. Epub 2012 Jul 17.

Department of Medicine, Veterans Affairs North Texas Health Care System, Dallas, TX 75216, USA.

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August 2012

MicroRNA-200a serves a key role in the decline of progesterone receptor function leading to term and preterm labor.

Proc Natl Acad Sci U S A 2012 May 23;109(19):7529-34. Epub 2012 Apr 23.

Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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May 2012

Metabolic stress-induced activation of FoxO1 triggers diabetic cardiomyopathy in mice.

J Clin Invest 2012 Mar 13;122(3):1109-18. Epub 2012 Feb 13.

Department of Internal Medicine (Cardiology), University of Texas Southwestern Medical Center, Dallas, Texas 75390-8573, USA.

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March 2012

Hypoxia increases sirtuin 1 expression in a hypoxia-inducible factor-dependent manner.

J Biol Chem 2011 Apr 23;286(16):13869-78. Epub 2011 Feb 23.

Department of Medicine, Veterans Affairs North Texas Health Care System, Dallas, Texas 75216, USA.

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April 2011

miR-200 family and targets, ZEB1 and ZEB2, modulate uterine quiescence and contractility during pregnancy and labor.

Proc Natl Acad Sci U S A 2010 Nov 15;107(48):20828-33. Epub 2010 Nov 15.

Department of Biochemistry, North Texas March of Dimes Birth Defects Center, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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November 2010

Surfactant protein A2 mutations associated with pulmonary fibrosis lead to protein instability and endoplasmic reticulum stress.

J Biol Chem 2010 Jul 13;285(29):22103-13. Epub 2010 May 13.

Eugene McDermott Center for Human Growth and Development, Dallas, Texas 75390, USA.

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July 2010

The CCAAT/enhancer binding protein beta (C/EBPbeta) cooperates with NFAT to control expression of the calcineurin regulatory protein RCAN1-4.

J Biol Chem 2010 May 6;285(22):16623-31. Epub 2010 Apr 6.

Department of Internal Medicine Cardiology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390, USA.

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May 2010

Regulation of PI3-kinase/Akt signaling by muscle-enriched microRNA-486.

Proc Natl Acad Sci U S A 2010 Mar 8;107(9):4218-23. Epub 2010 Feb 8.

Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9148, USA.

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March 2010

Cardiac myosin is a substrate for zipper-interacting protein kinase (ZIPK).

J Biol Chem 2010 Feb 28;285(8):5122-6. Epub 2009 Dec 28.

Department of Physiology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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February 2010

Regulation of hypoxia-inducible factor 2alpha signaling by the stress-responsive deacetylase sirtuin 1.

Science 2009 Jun;324(5932):1289-93

Veterans Affairs North Texas Health Care System, Department of Medicine, 4500 South Lancaster Road, Dallas, TX 75216, USA.

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June 2009

The basic helix-loop-helix transcription factor scleraxis regulates fibroblast collagen synthesis.

J Mol Cell Cardiol 2009 Aug 10;47(2):188-95. Epub 2009 Apr 10.

Institute of Cardiovascular Sciences, St. Boniface General Hospital Research Centre, University of Manitoba, 351 Tache Avenue, Winnipeg, Manitoba, Canada.

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August 2009