Robert Culverhouse

Robert Culverhouse

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Robert Culverhouse

Robert Culverhouse

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Variants in the CHRNA5-CHRNA3-CHRNB4 region of chromosome 15 predict gastrointestinal adverse events in the TTURC smoking cessation trial.

Nicotine Tob Res 2019 Mar 18. Epub 2019 Mar 18.

Department of Psychiatry, Washington University School of Medicine, Saint Louis, MO, USA.

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http://dx.doi.org/10.1093/ntr/ntz044DOI Listing
March 2019

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders.

Authors:
Raymond K Walters Renato Polimanti Emma C Johnson Jeanette N McClintick Mark J Adams Amy E Adkins Fazil Aliev Silviu-Alin Bacanu Anthony Batzler Sarah Bertelsen Joanna M Biernacka Tim B Bigdeli Li-Shiun Chen Toni-Kim Clarke Yi-Ling Chou Franziska Degenhardt Anna R Docherty Alexis C Edwards Pierre Fontanillas Jerome C Foo Louis Fox Josef Frank Ina Giegling Scott Gordon Laura M Hack Annette M Hartmann Sarah M Hartz Stefanie Heilmann-Heimbach Stefan Herms Colin Hodgkinson Per Hoffmann Jouke Jan Hottenga Martin A Kennedy Mervi Alanne-Kinnunen Bettina Konte Jari Lahti Marius Lahti-Pulkkinen Dongbing Lai Lannie Ligthart Anu Loukola Brion S Maher Hamdi Mbarek Andrew M McIntosh Matthew B McQueen Jacquelyn L Meyers Yuri Milaneschi Teemu Palviainen John F Pearson Roseann E Peterson Samuli Ripatti Euijung Ryu Nancy L Saccone Jessica E Salvatore Sandra Sanchez-Roige Melanie Schwandt Richard Sherva Fabian Streit Jana Strohmaier Nathaniel Thomas Jen-Chyong Wang Bradley T Webb Robbee Wedow Leah Wetherill Amanda G Wills Jason D Boardman Danfeng Chen Doo-Sup Choi William E Copeland Robert C Culverhouse Norbert Dahmen Louisa Degenhardt Benjamin W Domingue Sarah L Elson Mark A Frye Wolfgang Gäbel Caroline Hayward Marcus Ising Margaret Keyes Falk Kiefer John Kramer Samuel Kuperman Susanne Lucae Michael T Lynskey Wolfgang Maier Karl Mann Satu Männistö Bertram Müller-Myhsok Alison D Murray John I Nurnberger Aarno Palotie Ulrich Preuss Katri Räikkönen Maureen D Reynolds Monika Ridinger Norbert Scherbaum Marc A Schuckit Michael Soyka Jens Treutlein Stephanie Witt Norbert Wodarz Peter Zill Daniel E Adkins Joseph M Boden Dorret I Boomsma Laura J Bierut Sandra A Brown Kathleen K Bucholz Sven Cichon E Jane Costello Harriet de Wit Nancy Diazgranados Danielle M Dick Johan G Eriksson Lindsay A Farrer Tatiana M Foroud Nathan A Gillespie Alison M Goate David Goldman Richard A Grucza Dana B Hancock Kathleen Mullan Harris Andrew C Heath Victor Hesselbrock John K Hewitt Christian J Hopfer John Horwood William Iacono Eric O Johnson Jaakko A Kaprio Victor M Karpyak Kenneth S Kendler Henry R Kranzler Kenneth Krauter Paul Lichtenstein Penelope A Lind Matt McGue James MacKillop Pamela A F Madden Hermine H Maes Patrik Magnusson Nicholas G Martin Sarah E Medland Grant W Montgomery Elliot C Nelson Markus M Nöthen Abraham A Palmer Nancy L Pedersen Brenda W J H Penninx Bernice Porjesz John P Rice Marcella Rietschel Brien P Riley Richard Rose Dan Rujescu Pei-Hong Shen Judy Silberg Michael C Stallings Ralph E Tarter Michael M Vanyukov Scott Vrieze Tamara L Wall John B Whitfield Hongyu Zhao Benjamin M Neale Joel Gelernter Howard J Edenberg Arpana Agrawal

Nat Neurosci 2018 12 26;21(12):1656-1669. Epub 2018 Nov 26.

Washington University School of Medicine, Department of Psychiatry, St. Louis, MO, USA.

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http://dx.doi.org/10.1038/s41593-018-0275-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430207PMC
December 2018

The state of knowledge about the relationship between 5-HTTLPR, stress, and depression.

J Affect Disord 2018 03 11;228:205-206. Epub 2017 Dec 11.

Department of Psychiatry, Washington University in St. Louis School of Medicine, St. Louis, MO, USA.

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http://dx.doi.org/10.1016/j.jad.2017.12.002DOI Listing
March 2018

Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts.

Authors:
Tae-Hwi Schwantes-An Juan Zhang Li-Shiun Chen Sarah M Hartz Robert C Culverhouse Xiangning Chen Hilary Coon Josef Frank Helen M Kamens Bettina Konte Leena Kovanen Antti Latvala Lisa N Legrand Brion S Maher Whitney E Melroy Elliot C Nelson Mark W Reid Jason D Robinson Pei-Hong Shen Bao-Zhu Yang Judy A Andrews Paul Aveyard Olga Beltcheva Sandra A Brown Dale S Cannon Sven Cichon Robin P Corley Norbert Dahmen Louisa Degenhardt Tatiana Foroud Wolfgang Gaebel Ina Giegling Stephen J Glatt Richard A Grucza Jill Hardin Annette M Hartmann Andrew C Heath Stefan Herms Colin A Hodgkinson Per Hoffmann Hyman Hops David Huizinga Marcus Ising Eric O Johnson Elaine Johnstone Radka P Kaneva Kenneth S Kendler Falk Kiefer Henry R Kranzler Ken S Krauter Orna Levran Susanne Lucae Michael T Lynskey Wolfgang Maier Karl Mann Nicholas G Martin Manuel Mattheisen Grant W Montgomery Bertram Müller-Myhsok Michael F Murphy Michael C Neale Momchil A Nikolov Denise Nishita Markus M Nöthen John Nurnberger Timo Partonen Michele L Pergadia Maureen Reynolds Monika Ridinger Richard J Rose Noora Rouvinen-Lagerström Norbert Scherbaum Christine Schmäl Michael Soyka Michael C Stallings Michael Steffens Jens Treutlein Ming Tsuang Tamara L Wall Norbert Wodarz Vadim Yuferov Peter Zill Andrew W Bergen Jingchun Chen Paul M Cinciripini Howard J Edenberg Marissa A Ehringer Robert E Ferrell Joel Gelernter David Goldman John K Hewitt Christian J Hopfer William G Iacono Jaakko Kaprio Mary Jeanne Kreek Ivo M Kremensky Pamela A F Madden Matt McGue Marcus R Munafò Robert A Philibert Marcella Rietschel Alec Roy Dan Rujescu Sirkku T Saarikoski Gary E Swan Alexandre A Todorov Michael M Vanyukov Robert B Weiss Laura J Bierut Nancy L Saccone

Behav Genet 2016 Mar 21;46(2):151-69. Epub 2015 Sep 21.

Department of Genetics, Washington University School of Medicine, 4523 Clayton Avenue, Campus Box 8232, St. Louis, MO, 63110, USA.

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https://genepi.qimr.edu.au/contents/p/staff/Schwantes_An_Beh
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http://link.springer.com/10.1007/s10519-015-9737-3
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http://dx.doi.org/10.1007/s10519-015-9737-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752855PMC
March 2016

Identifying cryptic population structure in multigenerational pedigrees in a Mexican American sample.

BMC Proc 2014 17;8(Suppl 1):S4. Epub 2014 Jun 17.

Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, 63110 USA ; Department of Genetics, Washington University School of Medicine, St. Louis, MO, 63110 USA.

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http://dx.doi.org/10.1186/1753-6561-8-S1-S4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143674PMC
December 2014

Genotypic discrepancies arising from imputation.

BMC Proc 2014 17;8(Suppl 1 Genetic Analysis Workshop 18Vanessa Olmo):S17. Epub 2014 Jun 17.

Department of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110, USA ; Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1186/1753-6561-8-S1-S17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143754PMC
December 2014

Multiple distinct CHRNB3-CHRNA6 variants are genetic risk factors for nicotine dependence in African Americans and European Americans.

Addiction 2014 May 18;109(5):814-22. Epub 2014 Feb 18.

Department of Medicine, Washington University School of Medicine, Saint Louis, MO, USA; Division of Biostatistics, Washington University School of Medicine, Saint Louis, MO, USA.

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http://dx.doi.org/10.1111/add.12478DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984604PMC
May 2014

Protocol for a collaborative meta-analysis of 5-HTTLPR, stress, and depression.

BMC Psychiatry 2013 Nov 12;13:304. Epub 2013 Nov 12.

Department of Medicine, Washington University School of Medicine, St, Louis, MO, USA.

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http://dx.doi.org/10.1186/1471-244X-13-304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840571PMC
November 2013

Interpreting joint SNP analysis results: when are two distinct signals really two distinct signals?

Genet Epidemiol 2013 Apr 12;37(3):301-9. Epub 2013 Feb 12.

Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, USA.

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http://dx.doi.org/10.1002/gepi.21712DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743534PMC
April 2013

Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers.

Authors:
Sarah M Hartz Susan E Short Nancy L Saccone Robert Culverhouse LiShiun Chen Tae-Hwi Schwantes-An Hilary Coon Younghun Han Sarah H Stephens Juzhong Sun Xiangning Chen Francesca Ducci Nicole Dueker Nora Franceschini Josef Frank Frank Geller Daniel Gubjartsson Nadia N Hansel Chenhui Jiang Kaisu Keskitalo-Vuokko Zhen Liu Leo-Pekka Lyytikäinen Martha Michel Rajesh Rawal Albert Rosenberger Paul Scheet John R Shaffer Alexander Teumer John R Thompson Jacqueline M Vink Nicole Vogelzangs Angela S Wenzlaff William Wheeler Xiangjun Xiao Bao-Zhu Yang Steven H Aggen Anthony J Balmforth Sebastian E Baumeister Terri Beaty Siiri Bennett Andrew W Bergen Heather A Boyd Ulla Broms Harry Campbell Nilanjan Chatterjee Jingchun Chen Yu-Ching Cheng Sven Cichon David Couper Francesco Cucca Danielle M Dick Tatiana Foroud Helena Furberg Ina Giegling Fangyi Gu Alistair S Hall Jenni Hällfors Shizhong Han Annette M Hartmann Caroline Hayward Kauko Heikkilä John K Hewitt Jouke Jan Hottenga Majken K Jensen Pekka Jousilahti Marika Kaakinen Steven J Kittner Bettina Konte Tellervo Korhonen Maria-Teresa Landi Tiina Laatikainen Mark Leppert Steven M Levy Rasika A Mathias Daniel W McNeil Sarah E Medland Grant W Montgomery Thomas Muley Tanda Murray Matthias Nauck Kari North Michele Pergadia Ozren Polasek Erin M Ramos Samuli Ripatti Angela Risch Ingo Ruczinski Igor Rudan Veikko Salomaa David Schlessinger Unnur Styrkársdóttir Antonio Terracciano Manuela Uda Gonneke Willemsen Xifeng Wu Goncalo Abecasis Kathleen Barnes Heike Bickeböller Eric Boerwinkle Dorret I Boomsma Neil Caporaso Jubao Duan Howard J Edenberg Clyde Francks Pablo V Gejman Joel Gelernter Hans Jörgen Grabe Hyman Hops Marjo-Riitta Jarvelin Jorma Viikari Mika Kähönen Kenneth S Kendler Terho Lehtimäki Douglas F Levinson Mary L Marazita Jonathan Marchini Mads Melbye Braxton D Mitchell Jeffrey C Murray Markus M Nöthen Brenda W Penninx Olli Raitakari Marcella Rietschel Dan Rujescu Nilesh J Samani Alan R Sanders Ann G Schwartz Sanjay Shete Jianxin Shi Margaret Spitz Kari Stefansson Gary E Swan Thorgeir Thorgeirsson Henry Völzke Qingyi Wei H-Erich Wichmann Christopher I Amos Naomi Breslau Dale S Cannon Marissa Ehringer Richard Grucza Dorothy Hatsukami Andrew Heath Eric O Johnson Jaakko Kaprio Pamela Madden Nicholas G Martin Victoria L Stevens Jerry A Stitzel Robert B Weiss Peter Kraft Laura J Bierut

Arch Gen Psychiatry 2012 Aug;69(8):854-60

Washington University School of Medicine, St Louis, Missouri, USA.

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http://dx.doi.org/10.1001/archgenpsychiatry.2012.124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482121PMC
August 2012

A comparison of methods sensitive to interactions with small main effects.

Genet Epidemiol 2012 May 28;36(4):303-11. Epub 2012 Mar 28.

Department of Internal Medicine, Washington University in St. Louis School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1002/gepi.21622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357917PMC
May 2012

Linkage analysis merging replicate phenotypes: an application to three quantitative phenotypes in two African samples.

BMC Proc 2011 Nov 29;5 Suppl 9:S81. Epub 2011 Nov 29.

Department of Psychiatry, Washington University School of Medicine, 660 South Euclid Ave,, Campus Box 8134, St, Louis, MO 63110, USA.

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http://bmcproc.biomedcentral.com/articles/10.1186/1753-6561-
Publisher Site
http://dx.doi.org/10.1186/1753-6561-5-S9-S81DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287922PMC
November 2011

Stratify or adjust? Dealing with multiple populations when evaluating rare variants.

BMC Proc 2011 Nov 29;5 Suppl 9:S101. Epub 2011 Nov 29.

Department of Medicine, Washington University School of Medicine, 660 South Euclid Avenue, Saint Louis, MO 63110, USA.

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http://dx.doi.org/10.1186/1753-6561-5-S9-S101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287824PMC
November 2011

The restricted partition method.

Adv Genet 2010 ;72:117-39

Washington University in St Louis School of Medicine, St Louis, Missouri, USA.

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http://dx.doi.org/10.1016/B978-0-12-380862-2.00006-0DOI Listing
November 2010

Linkage, case-control association, and family-based association tests for complex disorders.

BMC Proc 2007 18;1 Suppl 1:S43. Epub 2007 Dec 18.

Department of Psychiatry, Washington University School of Medicine, 660 South Euclid, St. Louis, Missouri 63110, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367550PMC
http://dx.doi.org/10.1186/1753-6561-1-s1-s43DOI Listing
December 2009

Linkage and association analyses of principal components in expression data.

BMC Proc 2007 18;1 Suppl 1:S46. Epub 2007 Dec 18.

Department of Psychiatry, Washington University, 660 South Euclid, Box 8134, St, Louis, Missouri 63110, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367470PMC
http://dx.doi.org/10.1186/1753-6561-1-s1-s46DOI Listing
December 2009

Gene x gene and gene x environment interactions for complex disorders.

BMC Proc 2007 18;1 Suppl 1:S72. Epub 2007 Dec 18.

Department of Medicine, Washington University, 660 South Euclid, GMS-Box 8005, St, Louis, Missouri 63110, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367466PMC
http://dx.doi.org/10.1186/1753-6561-1-s1-s72DOI Listing
December 2009

Detecting population stratification using related individuals.

BMC Proc 2009 Dec 15;3 Suppl 7:S106. Epub 2009 Dec 15.

Department of Psychiatry, Washington University School of Medicine, 660 South Euclid, Campus Box 8134, St, Louis, Missouri 63110 USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795877PMC
http://dx.doi.org/10.1186/1753-6561-3-s7-s106DOI Listing
December 2009

A search for non-chromosome 6 susceptibility loci contributing to rheumatoid arthritis.

BMC Proc 2009 Dec 15;3 Suppl 7:S15. Epub 2009 Dec 15.

Department of Psychiatry, Washington University School of Medicine, 660 South Euclid, Campus Box 8134, St. Louis, Missouri 63110, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795911PMC
http://dx.doi.org/10.1186/1753-6561-3-s7-s15DOI Listing
December 2009

The Genetic Analysis Workshop 16 Problem 3: simulation of heritable longitudinal cardiovascular phenotypes based on actual genome-wide single-nucleotide polymorphisms in the Framingham Heart Study.

BMC Proc 2009 Dec 15;3 Suppl 7:S4. Epub 2009 Dec 15.

Division of Statistical Genomics, Washington University School of Medicine, 4444 Forest Park Boulevard, Campus Box 8506, St, Louis, Missouri 63108, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795938PMC
http://dx.doi.org/10.1186/1753-6561-3-s7-s4DOI Listing
December 2009

Power and false-positive rates for the restricted partition method (RPM) in a large candidate gene data set.

BMC Proc 2009 Dec 15;3 Suppl 7:S74. Epub 2009 Dec 15.

Department of Medicine, Washington University School of Medicine, 660 South Euclid Avenue, St, Louis, Missouri 63110, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795976PMC
http://dx.doi.org/10.1186/1753-6561-3-s7-s74DOI Listing
December 2009

DNA methylotype analysis in colorectal cancer.

Oncol Rep 2008 Oct;20(4):921-7

Department of Medicine, Washington University School of Medicine, Saint Louis, MO 63110, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294550PMC
October 2008

Gene by environment interactions.

Genet Epidemiol 2007 ;31 Suppl 1:S68-74

Department of Medicine, Washington University School of Medicine, 600 South Euclid, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1002/gepi.20282DOI Listing
April 2008

Methotrexate (MTX) pathway gene polymorphisms and their effects on MTX toxicity in Caucasian and African American patients with rheumatoid arthritis.

J Rheumatol 2008 Apr 15;35(4):572-9. Epub 2008 Mar 15.

Department of Medicine, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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April 2008

Irinotecan pharmacogenetics: influence of pharmacodynamic genes.

Clin Cancer Res 2008 Mar;14(6):1788-96

Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-07-1472DOI Listing
March 2008

MAGED2: a novel p53-dissociator.

Int J Oncol 2007 Nov;31(5):1205-11

Hematology and Medical Oncology, Ellis Fischel Cancer Center, University of Missouri-Columbia, Columbia, MO 65203, USA.

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November 2007

A mouse model for developing treatment for secondary liver tumors.

Int J Oncol 2005 Jul;27(1):113-20

Departmen of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.

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July 2005

Long-term stability of alcohol and other substance dependence diagnoses and habitual smoking: an evaluation after 5 years.

Arch Gen Psychiatry 2005 Jul;62(7):753-60

Department of Internal Medicine, Washington University in St Louis School of Medicine, St Louis, MO 63110-1026, USA.

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http://dx.doi.org/10.1001/archpsyc.62.7.753DOI Listing
July 2005

Detecting epistatic interactions contributing to quantitative traits.

Genet Epidemiol 2004 Sep;27(2):141-52

Department of Medicine, Washington University in St. Louis School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1002/gepi.20006DOI Listing
September 2004

Single nucleotide polymorphism profiling across the methotrexate pathway in normal subjects and patients with rheumatoid arthritis.

Pharmacogenomics 2004 Jul;5(5):559-69

Department of Medicine, Washington University School of Medicine, St Louis, Missouri 63110, USA. prangana

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http://dx.doi.org/10.1517/14622416.5.5.559DOI Listing
July 2004

Analyzing microarray data using cluster analysis.

Pharmacogenomics 2003 Jan;4(1):41-52

Department of Medicine, Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8005, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1517/phgs.4.1.41.22581DOI Listing
January 2003

A perspective on epistasis: limits of models displaying no main effect.

Am J Hum Genet 2002 Feb 8;70(2):461-71. Epub 2002 Jan 8.

Department of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110-1093, USA.

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http://dx.doi.org/10.1086/338759DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC384920PMC
February 2002