Robert Clarke

Robert Clarke

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Robert Clarke

Publications by authors named "Robert Clarke"

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PAK4 regulates stemness and progression in endocrine resistant ER-positive metastatic breast cancer.

Cancer Lett 2019 Aug 20;458:66-75. Epub 2019 May 20.

Breast Biology Group, Manchester Breast Centre, Division of Cancer Sciences, Oglesby Cancer Research Building, University of Manchester, Manchester, M20 4GJ, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2019.05.014DOI Listing
August 2019

Beneficial Effects of Milk Consumption on Lean Body Mass.

Authors:
Robert Clarke

Clin Chem 2019 Jun;65(6):718-719

Clinical Trial Service Unit and Epidemiological Studies Unit, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1373/clinchem.2019.305581DOI Listing
June 2019

Targeting Endometrial Cancer Stem Cell Activity with Metformin Is Inhibited by Patient-Derived Adipocyte-Secreted Factors.

Cancers (Basel) 2019 May 11;11(5). Epub 2019 May 11.

Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester M13 9WL, UK.

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http://dx.doi.org/10.3390/cancers11050653DOI Listing
May 2019

Assessment of the Role of Carotid Atherosclerosis in the Association Between Major Cardiovascular Risk Factors and Ischemic Stroke Subtypes.

JAMA Netw Open 2019 May 3;2(5):e194873. Epub 2019 May 3.

Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1001/jamanetworkopen.2019.4873DOI Listing
May 2019

Estrogen-Induced Apoptosis in Breast Cancers Is Phenocopied by Blocking Dephosphorylation of Eukaryotic Initiation Factor 2 Alpha (eIF2α) Protein.

Mol Cancer Res 2019 04 17;17(4):918-928. Epub 2019 Jan 17.

Department of Oncology, Georgetown-Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington D.C.

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http://dx.doi.org/10.1158/1541-7786.MCR-18-0481DOI Listing
April 2019

Causal associations of blood lipids with risk of ischemic stroke and intracerebral hemorrhage in Chinese adults.

Nat Med 2019 04 11;25(4):569-574. Epub 2019 Mar 11.

Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.

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http://www.nature.com/articles/s41591-019-0366-x
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http://dx.doi.org/10.1038/s41591-019-0366-xDOI Listing
April 2019

Systems biology: perspectives on multiscale modeling in research on endocrine-related cancers.

Endocr Relat Cancer 2019 Apr 1. Epub 2019 Apr 1.

Y Wang, Electrical and Electronic Engineering, Virginia Polytechnic Institute and State University, Blacksburg, United States.

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http://dx.doi.org/10.1530/ERC-18-0309DOI Listing
April 2019

Cardiovascular risk factors and Parkinson's disease in 500,000 Chinese adults.

Ann Clin Transl Neurol 2019 Apr 10;6(4):624-632. Epub 2019 Mar 10.

Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU) Nuffield Department of Population Health University of Oxford Oxford United Kingdom.

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http://dx.doi.org/10.1002/acn3.732DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469341PMC
April 2019

Relative effects of LDL-C on ischemic stroke and coronary disease: A Mendelian randomization study.

Neurology 2019 Mar 20;92(11):e1176-e1187. Epub 2019 Feb 20.

From the Clinical Trial Service Unit and Epidemiological Studies Unit (E.V.-M., S.P., R.C., T.S., J.C.H.) and MRC Population Health Research Unit (S.P.), Nuffield Department of Population Health, University of Oxford, UK; and Departments of Neurology and Public Health Sciences (B.B.W.), University of Virginia School of Medicine, Charlottesville, VA.

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http://dx.doi.org/10.1212/WNL.0000000000007091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511103PMC
March 2019

Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.

Authors:
Brian W Kunkle Benjamin Grenier-Boley Rebecca Sims Joshua C Bis Vincent Damotte Adam C Naj Anne Boland Maria Vronskaya Sven J van der Lee Alexandre Amlie-Wolf Céline Bellenguez Aura Frizatti Vincent Chouraki Eden R Martin Kristel Sleegers Nandini Badarinarayan Johanna Jakobsdottir Kara L Hamilton-Nelson Sonia Moreno-Grau Robert Olaso Rachel Raybould Yuning Chen Amanda B Kuzma Mikko Hiltunen Taniesha Morgan Shahzad Ahmad Badri N Vardarajan Jacques Epelbaum Per Hoffmann Merce Boada Gary W Beecham Jean-Guillaume Garnier Denise Harold Annette L Fitzpatrick Otto Valladares Marie-Laure Moutet Amy Gerrish Albert V Smith Liming Qu Delphine Bacq Nicola Denning Xueqiu Jian Yi Zhao Maria Del Zompo Nick C Fox Seung-Hoan Choi Ignacio Mateo Joseph T Hughes Hieab H Adams John Malamon Florentino Sanchez-Garcia Yogen Patel Jennifer A Brody Beth A Dombroski Maria Candida Deniz Naranjo Makrina Daniilidou Gudny Eiriksdottir Shubhabrata Mukherjee David Wallon James Uphill Thor Aspelund Laura B Cantwell Fabienne Garzia Daniela Galimberti Edith Hofer Mariusz Butkiewicz Bertrand Fin Elio Scarpini Chloe Sarnowski Will S Bush Stéphane Meslage Johannes Kornhuber Charles C White Yuenjoo Song Robert C Barber Sebastiaan Engelborghs Sabrina Sordon Dina Voijnovic Perrie M Adams Rik Vandenberghe Manuel Mayhaus L Adrienne Cupples Marilyn S Albert Peter P De Deyn Wei Gu Jayanadra J Himali Duane Beekly Alessio Squassina Annette M Hartmann Adelina Orellana Deborah Blacker Eloy Rodriguez-Rodriguez Simon Lovestone Melissa E Garcia Rachelle S Doody Carmen Munoz-Fernadez Rebecca Sussams Honghuang Lin Thomas J Fairchild Yolanda A Benito Clive Holmes Hata Karamujić-Čomić Matthew P Frosch Hakan Thonberg Wolfgang Maier Gena Roschupkin Bernardino Ghetti Vilmantas Giedraitis Amit Kawalia Shuo Li Ryan M Huebinger Lena Kilander Susanne Moebus Isabel Hernández M Ilyas Kamboh RoseMarie Brundin James Turton Qiong Yang Mindy J Katz Letizia Concari Jenny Lord Alexa S Beiser C Dirk Keene Seppo Helisalmi Iwona Kloszewska Walter A Kukull Anne Maria Koivisto Aoibhinn Lynch Lluís Tarraga Eric B Larson Annakaisa Haapasalo Brian Lawlor Thomas H Mosley Richard B Lipton Vincenzo Solfrizzi Michael Gill W T Longstreth Thomas J Montine Vincenza Frisardi Monica Diez-Fairen Fernando Rivadeneira Ronald C Petersen Vincent Deramecourt Ignacio Alvarez Francesca Salani Antonio Ciaramella Eric Boerwinkle Eric M Reiman Nathalie Fievet Jerome I Rotter Joan S Reisch Olivier Hanon Chiara Cupidi A G Andre Uitterlinden Donald R Royall Carole Dufouil Raffaele Giovanni Maletta Itziar de Rojas Mary Sano Alexis Brice Roberta Cecchetti Peter St George-Hyslop Karen Ritchie Magda Tsolaki Debby W Tsuang Bruno Dubois David Craig Chuang-Kuo Wu Hilkka Soininen Despoina Avramidou Roger L Albin Laura Fratiglioni Antonia Germanou Liana G Apostolova Lina Keller Maria Koutroumani Steven E Arnold Francesco Panza Olymbia Gkatzima Sanjay Asthana Didier Hannequin Patrice Whitehead Craig S Atwood Paolo Caffarra Harald Hampel Inés Quintela Ángel Carracedo Lars Lannfelt David C Rubinsztein Lisa L Barnes Florence Pasquier Lutz Frölich Sandra Barral Bernadette McGuinness Thomas G Beach Janet A Johnston James T Becker Peter Passmore Eileen H Bigio Jonathan M Schott Thomas D Bird Jason D Warren Bradley F Boeve Michelle K Lupton James D Bowen Petra Proitsi Adam Boxer John F Powell James R Burke John S K Kauwe Jeffrey M Burns Michelangelo Mancuso Joseph D Buxbaum Ubaldo Bonuccelli Nigel J Cairns Andrew McQuillin Chuanhai Cao Gill Livingston Chris S Carlson Nicholas J Bass Cynthia M Carlsson John Hardy Regina M Carney Jose Bras Minerva M Carrasquillo Rita Guerreiro Mariet Allen Helena C Chui Elizabeth Fisher Carlo Masullo Elizabeth A Crocco Charles DeCarli Gina Bisceglio Malcolm Dick Li Ma Ranjan Duara Neill R Graff-Radford Denis A Evans Angela Hodges Kelley M Faber Martin Scherer Kenneth B Fallon Matthias Riemenschneider David W Fardo Reinhard Heun Martin R Farlow Heike Kölsch Steven Ferris Markus Leber Tatiana M Foroud Isabella Heuser Douglas R Galasko Ina Giegling Marla Gearing Michael Hüll Daniel H Geschwind John R Gilbert John Morris Robert C Green Kevin Mayo John H Growdon Thomas Feulner Ronald L Hamilton Lindy E Harrell Dmitriy Drichel Lawrence S Honig Thomas D Cushion Matthew J Huentelman Paul Hollingworth Christine M Hulette Bradley T Hyman Rachel Marshall Gail P Jarvik Alun Meggy Erin Abner Georgina E Menzies Lee-Way Jin Ganna Leonenko Luis M Real Gyungah R Jun Clinton T Baldwin Detelina Grozeva Anna Karydas Giancarlo Russo Jeffrey A Kaye Ronald Kim Frank Jessen Neil W Kowall Bruno Vellas Joel H Kramer Emma Vardy Frank M LaFerla Karl-Heinz Jöckel James J Lah Martin Dichgans James B Leverenz David Mann Allan I Levey Stuart Pickering-Brown Andrew P Lieberman Norman Klopp Kathryn L Lunetta H-Erich Wichmann Constantine G Lyketsos Kevin Morgan Daniel C Marson Kristelle Brown Frank Martiniuk Christopher Medway Deborah C Mash Markus M Nöthen Eliezer Masliah Nigel M Hooper Wayne C McCormick Antonio Daniele Susan M McCurry Anthony Bayer Andrew N McDavid John Gallacher Ann C McKee Hendrik van den Bussche Marsel Mesulam Carol Brayne Bruce L Miller Steffi Riedel-Heller Carol A Miller Joshua W Miller Ammar Al-Chalabi John C Morris Christopher E Shaw Amanda J Myers Jens Wiltfang Sid O'Bryant John M Olichney Victoria Alvarez Joseph E Parisi Andrew B Singleton Henry L Paulson John Collinge William R Perry Simon Mead Elaine Peskind David H Cribbs Martin Rossor Aimee Pierce Natalie S Ryan Wayne W Poon Benedetta Nacmias Huntington Potter Sandro Sorbi Joseph F Quinn Eleonora Sacchinelli Ashok Raj Gianfranco Spalletta Murray Raskind Carlo Caltagirone Paola Bossù Maria Donata Orfei Barry Reisberg Robert Clarke Christiane Reitz A David Smith John M Ringman Donald Warden Erik D Roberson Gordon Wilcock Ekaterina Rogaeva Amalia Cecilia Bruni Howard J Rosen Maura Gallo Roger N Rosenberg Yoav Ben-Shlomo Mark A Sager Patrizia Mecocci Andrew J Saykin Pau Pastor Michael L Cuccaro Jeffery M Vance Julie A Schneider Lori S Schneider Susan Slifer William W Seeley Amanda G Smith Joshua A Sonnen Salvatore Spina Robert A Stern Russell H Swerdlow Mitchell Tang Rudolph E Tanzi John Q Trojanowski Juan C Troncoso Vivianna M Van Deerlin Linda J Van Eldik Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Kirk C Wilhelmsen Jennifer Williamson Thomas S Wingo Randall L Woltjer Clinton B Wright Chang-En Yu Lei Yu Yasaman Saba Alberto Pilotto Maria J Bullido Oliver Peters Paul K Crane David Bennett Paola Bosco Eliecer Coto Virginia Boccardi Phil L De Jager Alberto Lleo Nick Warner Oscar L Lopez Martin Ingelsson Panagiotis Deloukas Carlos Cruchaga Caroline Graff Rhian Gwilliam Myriam Fornage Alison M Goate Pascual Sanchez-Juan Patrick G Kehoe Najaf Amin Nilifur Ertekin-Taner Claudine Berr Stéphanie Debette Seth Love Lenore J Launer Steven G Younkin Jean-Francois Dartigues Chris Corcoran M Arfan Ikram Dennis W Dickson Gael Nicolas Dominique Campion JoAnn Tschanz Helena Schmidt Hakon Hakonarson Jordi Clarimon Ron Munger Reinhold Schmidt Lindsay A Farrer Christine Van Broeckhoven Michael C O'Donovan Anita L DeStefano Lesley Jones Jonathan L Haines Jean-Francois Deleuze Michael J Owen Vilmundur Gudnason Richard Mayeux Valentina Escott-Price Bruce M Psaty Alfredo Ramirez Li-San Wang Agustin Ruiz Cornelia M van Duijn Peter A Holmans Sudha Seshadri Julie Williams Phillippe Amouyel Gerard D Schellenberg Jean-Charles Lambert Margaret A Pericak-Vance

Nat Genet 2019 03 28;51(3):414-430. Epub 2019 Feb 28.

John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.

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http://dx.doi.org/10.1038/s41588-019-0358-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463297PMC
March 2019

Adiposity in middle and old age and risk of death from dementia: 40-year follow-up of 19,000 men in the Whitehall study.

Age Ageing 2019 Jan 9. Epub 2019 Jan 9.

Faculty of Epidemiology and Population Health, Department of Community Medicine, London School of Hygiene and Tropical Medicine and Adjunct Professor of Epidemiology, UiT the Arctic University of Norway, Tromsø, Norway.

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http://dx.doi.org/10.1093/ageing/afy182DOI Listing
January 2019

Blood Pressure and Risk of Subarachnoid Hemorrhage in China.

Stroke 2018 Dec 7:STROKEAHA118022239. Epub 2018 Dec 7.

From the Nuffield Department of Population Health, University of Oxford, United Kingdom (I.J.M., R.C., B.L., X.L.K., Z.C., Y.C., S.L.).

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http://dx.doi.org/10.1161/STROKEAHA.118.022239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314500PMC
December 2018

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.

Authors:
Symen Ligthart Ahmad Vaez Urmo Võsa Maria G Stathopoulou Paul S de Vries Bram P Prins Peter J Van der Most Toshiko Tanaka Elnaz Naderi Lynda M Rose Ying Wu Robert Karlsson Maja Barbalic Honghuang Lin René Pool Gu Zhu Aurélien Macé Carlo Sidore Stella Trompet Massimo Mangino Maria Sabater-Lleal John P Kemp Ali Abbasi Tim Kacprowski Niek Verweij Albert V Smith Tao Huang Carola Marzi Mary F Feitosa Kurt K Lohman Marcus E Kleber Yuri Milaneschi Christian Mueller Mahmudul Huq Efthymia Vlachopoulou Leo-Pekka Lyytikäinen Christopher Oldmeadow Joris Deelen Markus Perola Jing Hua Zhao Bjarke Feenstra Marzyeh Amini Jari Lahti Katharina E Schraut Myriam Fornage Bhoom Suktitipat Wei-Min Chen Xiaohui Li Teresa Nutile Giovanni Malerba Jian'an Luan Tom Bak Nicholas Schork Fabiola Del Greco M Elisabeth Thiering Anubha Mahajan Riccardo E Marioni Evelin Mihailov Joel Eriksson Ayse Bilge Ozel Weihua Zhang Maria Nethander Yu-Ching Cheng Stella Aslibekyan Wei Ang Ilaria Gandin Loïc Yengo Laura Portas Charles Kooperberg Edith Hofer Kumar B Rajan Claudia Schurmann Wouter den Hollander Tarunveer S Ahluwalia Jing Zhao Harmen H M Draisma Ian Ford Nicholas Timpson Alexander Teumer Hongyan Huang Simone Wahl YongMei Liu Jie Huang Hae-Won Uh Frank Geller Peter K Joshi Lisa R Yanek Elisabetta Trabetti Benjamin Lehne Diego Vozzi Marie Verbanck Ginevra Biino Yasaman Saba Ingrid Meulenbelt Jeff R O'Connell Markku Laakso Franco Giulianini Patrik K E Magnusson Christie M Ballantyne Jouke Jan Hottenga Grant W Montgomery Fernando Rivadineira Rico Rueedi Maristella Steri Karl-Heinz Herzig David J Stott Cristina Menni Mattias Frånberg Beate St Pourcain Stephan B Felix Tune H Pers Stephan J L Bakker Peter Kraft Annette Peters Dhananjay Vaidya Graciela Delgado Johannes H Smit Vera Großmann Juha Sinisalo Ilkka Seppälä Stephen R Williams Elizabeth G Holliday Matthijs Moed Claudia Langenberg Katri Räikkönen Jingzhong Ding Harry Campbell Michele M Sale Yii-Der I Chen Alan L James Daniela Ruggiero Nicole Soranzo Catharina A Hartman Erin N Smith Gerald S Berenson Christian Fuchsberger Dena Hernandez Carla M T Tiesler Vilmantas Giedraitis David Liewald Krista Fischer Dan Mellström Anders Larsson Yunmei Wang William R Scott Matthias Lorentzon John Beilby Kathleen A Ryan Craig E Pennell Dragana Vuckovic Beverly Balkau Maria Pina Concas Reinhold Schmidt Carlos F Mendes de Leon Erwin P Bottinger Margreet Kloppenburg Lavinia Paternoster Michael Boehnke A W Musk Gonneke Willemsen David M Evans Pamela A F Madden Mika Kähönen Zoltán Kutalik Magdalena Zoledziewska Ville Karhunen Stephen B Kritchevsky Naveed Sattar Genevieve Lachance Robert Clarke Tamara B Harris Olli T Raitakari John R Attia Diana van Heemst Eero Kajantie Rossella Sorice Giovanni Gambaro Robert A Scott Andrew A Hicks Luigi Ferrucci Marie Standl Cecilia M Lindgren John M Starr Magnus Karlsson Lars Lind Jun Z Li John C Chambers Trevor A Mori Eco J C N de Geus Andrew C Heath Nicholas G Martin Juha Auvinen Brendan M Buckley Anton J M de Craen Melanie Waldenberger Konstantin Strauch Thomas Meitinger Rodney J Scott Mark McEvoy Marian Beekman Cristina Bombieri Paul M Ridker Karen L Mohlke Nancy L Pedersen Alanna C Morrison Dorret I Boomsma John B Whitfield David P Strachan Albert Hofman Peter Vollenweider Francesco Cucca Marjo-Riitta Jarvelin J Wouter Jukema Tim D Spector Anders Hamsten Tanja Zeller André G Uitterlinden Matthias Nauck Vilmundur Gudnason Lu Qi Harald Grallert Ingrid B Borecki Jerome I Rotter Winfried März Philipp S Wild Marja-Liisa Lokki Michael Boyle Veikko Salomaa Mads Melbye Johan G Eriksson James F Wilson Brenda W J H Penninx Diane M Becker Bradford B Worrall Greg Gibson Ronald M Krauss Marina Ciullo Gianluigi Zaza Nicholas J Wareham Albertine J Oldehinkel Lyle J Palmer Sarah S Murray Peter P Pramstaller Stefania Bandinelli Joachim Heinrich Erik Ingelsson Ian J Deary Reedik Mägi Liesbeth Vandenput Pim van der Harst Karl C Desch Jaspal S Kooner Claes Ohlsson Caroline Hayward Terho Lehtimäki Alan R Shuldiner Donna K Arnett Lawrence J Beilin Antonietta Robino Philippe Froguel Mario Pirastu Tine Jess Wolfgang Koenig Ruth J F Loos Denis A Evans Helena Schmidt George Davey Smith P Eline Slagboom Gudny Eiriksdottir Andrew P Morris Bruce M Psaty Russell P Tracy Ilja M Nolte Eric Boerwinkle Sophie Visvikis-Siest Alex P Reiner Myron Gross Joshua C Bis Lude Franke Oscar H Franco Emelia J Benjamin Daniel I Chasman Josée Dupuis Harold Snieder Abbas Dehghan Behrooz Z Alizadeh

Am J Hum Genet 2018 11;103(5):691-706

Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, the Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029297183032
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http://dx.doi.org/10.1016/j.ajhg.2018.09.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218410PMC
November 2018

Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

Nat Commun 2018 11 28;9(1):5052. Epub 2018 Nov 28.

Medical Genomics Center, National Center for Global Health and Medicine, Tokyo, 162-8655, Japan.

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http://dx.doi.org/10.1038/s41467-018-07345-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261994PMC
November 2018

Autophagy and unfolded protein response (UPR) regulate mammary gland involution by restraining apoptosis-driven irreversible changes.

Cell Death Discov 2018 15;4:40. Epub 2018 Oct 15.

1Department of Oncology and Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057 USA.

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http://dx.doi.org/10.1038/s41420-018-0105-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186758PMC
October 2018

Questioning the Associations of ω-3 Fatty Acid Supplement Use With Cardiovascular Disease Risks-Reply.

JAMA Cardiol 2018 Aug;3(8):781-782

Clinical Trial Service Unit, Nuffield Department of Population Health, University of Oxford, Oxford, England.

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http://dx.doi.org/10.1001/jamacardio.2018.1312DOI Listing
August 2018

Ethnicity influences breast cancer stem cells' drug resistance.

Breast J 2018 07 2;24(4):701-703. Epub 2018 Mar 2.

Breast Biology Group, Division of Molecular and Clinical Cancer Sciences, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1111/tbj.13021DOI Listing
July 2018

Blastocyst development rate influences implantation and live birth rates of similarly graded euploid blastocysts.

Fertil Steril 2018 07 13;110(1):95-102.e1. Epub 2018 Jun 13.

Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medicine, New York, New York 10021.

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http://dx.doi.org/10.1016/j.fertnstert.2018.03.032DOI Listing
July 2018

Genomic Response to Vitamin D Supplementation in the Setting of a Randomized, Placebo-Controlled Trial.

EBioMedicine 2018 May 10;31:133-142. Epub 2018 Apr 10.

Wellcome Centre for Human Genetics (WHG), Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2018.04.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013786PMC
May 2018

Lack of genetic support for shared aetiology of Coronary Artery Disease and Late-onset Alzheimer's disease.

Sci Rep 2018 May 8;8(1):7102. Epub 2018 May 8.

Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1038/s41598-018-25460-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940751PMC
May 2018

Smoking and smoking cessation in relation to risk of diabetes in Chinese men and women: a 9-year prospective study of 0·5 million people.

Lancet Public Health 2018 04 13;3(4):e167-e176. Epub 2018 Mar 13.

Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK. Electronic address:

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http://dx.doi.org/10.1016/S2468-2667(18)30026-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887081PMC
April 2018

Estrogenicity of essential oils is not required to relieve symptoms of urogenital atrophy in breast cancer survivors.

Ther Adv Med Oncol 2018 2;10:1758835918766189. Epub 2018 Apr 2.

Breast Cancer Now Research Unit, Division of Cancer Sciences, University of Manchester, Manchester Cancer Research Centre, 555 Wilmslow Road, Manchester M20 4GJ, UK.

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http://dx.doi.org/10.1177/1758835918766189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5888815PMC
April 2018

Plasma cytokines and risk of coronary heart disease in the PROCARDIS study.

Open Heart 2018 25;5(1):e000807. Epub 2018 Apr 25.

Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1136/openhrt-2018-000807DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922567PMC
April 2018

The Role of Steroid Hormones in Breast and Effects on Cancer Stem Cells.

Curr Stem Cell Rep 2018 13;4(1):81-94. Epub 2018 Mar 13.

Breast Biology Group, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine, and Health, Manchester Cancer Research Centre, Wilmslow Road, Manchester, M20 4GJ UK.

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http://dx.doi.org/10.1007/s40778-018-0114-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866269PMC
March 2018

Lipids, Lipoproteins, and Metabolites and Risk of Myocardial Infarction and Stroke.

J Am Coll Cardiol 2018 Feb;71(6):620-632

Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2017.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811927PMC
February 2018

Patterns and management of chronic obstructive pulmonary disease in urban and rural China: a community-based survey of 25 000 adults across 10 regions.

BMJ Open Respir Res 2018 19;5(1):e000267. Epub 2018 Feb 19.

Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1136/bmjresp-2017-000267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844384PMC
February 2018

Introduction: Cancer Gene Networks.

Authors:
Robert Clarke

Methods Mol Biol 2017 ;1513:1-9

Department of Oncology, Georgetown Lombardi Comprehensive Cancer Center, W405A Research Building, 3970 Reservoir NW, Washington, DC, 20057, USA.

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http://dx.doi.org/10.1007/978-1-4939-6539-7_1DOI Listing
January 2018

SparseIso: a novel Bayesian approach to identify alternatively spliced isoforms from RNA-seq data.

Bioinformatics 2018 01;34(1):56-63

Bradley Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA 22203, USA.

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http://dx.doi.org/10.1093/bioinformatics/btx557DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870564PMC
January 2018

Association of Physical Activity With Risk of Major Cardiovascular Diseases in Chinese Men and Women.

JAMA Cardiol 2017 12;2(12):1349-1358

Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, England.

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http://dx.doi.org/10.1001/jamacardio.2017.4069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814992PMC
December 2017

GPER mediates the angiocrine actions induced by IGF1 through the HIF-1α/VEGF pathway in the breast tumor microenvironment.

Breast Cancer Res 2017 Dec 6;19(1):129. Epub 2017 Dec 6.

Breast Cancer Now Research Unit, Division of Cancer Sciences, Manchester Cancer Research Centre, University of Manchester, Wilmslow Road, Manchester, M204GJ, UK.

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http://dx.doi.org/10.1186/s13058-017-0923-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719673PMC
December 2017

G Protein-Coupled Receptors at the Crossroad between Physiologic and Pathologic Angiogenesis: Old Paradigms and Emerging Concepts.

Int J Mol Sci 2017 Dec 14;18(12). Epub 2017 Dec 14.

Department of Pharmacy, Health and Nutrition Sciences, University of Calabria via Savinio, 87036 Rende, Italy.

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http://dx.doi.org/10.3390/ijms18122713DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751314PMC
December 2017

EGR1 regulates cellular metabolism and survival in endocrine resistant breast cancer.

Oncotarget 2017 Nov 30;8(57):96865-96884. Epub 2017 May 30.

Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, USA.

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http://dx.doi.org/10.18632/oncotarget.18292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722529PMC
November 2017

Effects of Vitamin D on Blood Pressure, Arterial Stiffness, and Cardiac Function in Older People After 1 Year: BEST-D (Biochemical Efficacy and Safety Trial of Vitamin D).

J Am Heart Assoc 2017 Oct 24;6(10). Epub 2017 Oct 24.

Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, United Kingdom

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http://dx.doi.org/10.1161/JAHA.117.005707DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721827PMC
October 2017

CyNetSVM: A Cytoscape App for Cancer Biomarker Identification Using Network Constrained Support Vector Machines.

PLoS One 2017 25;12(1):e0170482. Epub 2017 Jan 25.

Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, Virginia, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0170482PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266326PMC
August 2017

Breast cancer cell obatoclax response characterization using passivated-electrode insulator-based dielectrophoresis.

Electrophoresis 2017 08 5;38(16):1988-1995. Epub 2017 Jul 5.

VT MEMS Lab, The Bradley Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Blacksburg, VA, USA.

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http://dx.doi.org/10.1002/elps.201600447DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976885PMC
August 2017

Direct Unequal Cleavages: Embryo Developmental Competence, Genetic Constitution and Clinical Outcome.

PLoS One 2016 1;11(12):e0166398. Epub 2016 Dec 1.

Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medicine, New York, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0166398PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5132229PMC
June 2017

Tissue Factor promotes breast cancer stem cell activity in vitro.

Oncotarget 2017 Apr;8(16):25915-25927

The University of Manchester, Manchester Academic Health Science Centre, Department of Academic Surgery, University Hospital of South Manchester, Manchester, UK.

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http://dx.doi.org/10.18632/oncotarget.13928DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432226PMC
April 2017

Burden of carotid artery atherosclerosis in Chinese adults: Implications for future risk of cardiovascular diseases.

Eur J Prev Cardiol 2017 04 27;24(6):647-656. Epub 2017 Jan 27.

1 Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, UK.

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http://dx.doi.org/10.1177/2047487317689973DOI Listing
April 2017

A Replicated, Genome-Wide Significant Association of Aortic Stenosis With a Genetic Variant for Lipoprotein(a): Meta-Analysis of Published and Novel Data.

Circulation 2017 03;135(12):1181-1183

From Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, United Kingdom (B.J.C., R.C.T., J.G.); British Heart Foundation Centre of Research Excellence, University of Oxford, United Kingdom (B.J.C.); Kolling Institute, University of Sydney, Australia (S.C.); Department of Cardiology, Royal North Shore Hospital, Sydney, Australia (S.C.); Guy's and St Thomas' Hospitals, London, United Kingdom (B.P.); Department of Medicine, McGill University, Montreal, QC, Canada (J.C.E., G.T.); McGill University and Genome Quebec Innovation Centre, Montreal, QC, Canada (M.L.); Preventive and Genomic Cardiology, McGill University Health Centre and Research Institute, Montreal, QC, Canada (G.T.); and Clinical Trial Service Unit and Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, United Kingdom (R.C.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.026103DOI Listing
March 2017

Validity of COPD diagnoses reported through nationwide health insurance systems in the People's Republic of China.

Int J Chron Obstruct Pulmon Dis 2016 1;11:419-30. Epub 2016 Mar 1.

Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.2147/COPD.S100736DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780206PMC
January 2017

DM-BLD: differential methylation detection using a hierarchical Bayesian model exploiting local dependency.

Bioinformatics 2017 01 11;33(2):161-168. Epub 2016 Sep 11.

Bradley Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, 900 North Glebe Road, Arlington, VA 22203, USA.

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https://academic.oup.com/bioinformatics/article-lookup/doi/1
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http://dx.doi.org/10.1093/bioinformatics/btw596DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5254079PMC
January 2017

PSSV: a novel pattern-based probabilistic approach for somatic structural variation identification.

Bioinformatics 2017 01 21;33(2):177-183. Epub 2016 Sep 21.

Bradley Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA 22203, USA.

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http://dx.doi.org/10.1093/bioinformatics/btw605DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5254081PMC
January 2017

Patient-derived Mammosphere and Xenograft Tumour Initiation Correlates with Progression to Metastasis.

J Mammary Gland Biol Neoplasia 2016 12 28;21(3-4):99-109. Epub 2016 Sep 28.

Breast Biology Group, Breast Cancer Now Research Unit, Division of Molecular and Clinical Cancer Sciences, Manchester Cancer Research Centre, University of Manchester, Wilmslow Road, Manchester, M20 4QL, UK.

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http://dx.doi.org/10.1007/s10911-016-9361-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159442PMC
December 2016

Erratum to: Patient-Derived Mammosphere and Xenograft Tumour Initiation Correlates with Progression to Metastasis.

J Mammary Gland Biol Neoplasia 2016 12;21(3-4):111

Breast Biology Group, Breast Cancer Now Research Unit, Division of Molecular and Clinical Cancer Sciences, Manchester Cancer, Research Centre, University of Manchester, Wilmslow Road, Manchester, M20 4QL, UK.

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http://dx.doi.org/10.1007/s10911-016-9364-5DOI Listing
December 2016

Associations of Epicardial, Abdominal, and Overall Adiposity With Atrial Fibrillation.

Circ Arrhythm Electrophysiol 2016 Dec;9(12)

From the Clinical Trial Service Unit and Epidemiological Studies Unit (C.X.W., R.C.), George Institute for Global Health (C.A.E.), Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (A.O.), University of Oxford, United Kingdom; Churchill Hospital, Oxford University Hospitals NHS Trust, United Kingdom (M.T.S.); Faculty of Medicine, University of Toronto, Ontario, Canada (A.O.); Centre for Heart Rhythm Disorders, South Australian Health and Medical Research Institute, University of Adelaide and Royal Adelaide Hospital, Adelaide, South Australia, Australia (R.M., D.H.L., R.K.P., P.S.); Monash Cardiovascular Research Centre, Department of Medicine, Monash Medical Centre, Monash University and Monash Health, Melbourne, Victoria, Australia (D.T.W.); and Department of Cardiology, Flinders Medical Centre, Adelaide, South Australia, Australia (J.B.S.).

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http://dx.doi.org/10.1161/CIRCEP.116.004378DOI Listing
December 2016

Complexity galore: 3D cultures, biomechanics and systems medicine at the eighth ENBDC workshop "Methods in Mammary Gland Development and Cancer".

Breast Cancer Res 2016 11 25;18(1):115. Epub 2016 Nov 25.

Section of Molecular Cytology and Van Leeuwenhoek Centre for Advance Microscopy, Swammerdam Institute for Life Sciences, University of Amsterdam, Science Park 904, 1098, XH, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1186/s13058-016-0777-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124316PMC
November 2016

Biologically inspired survival analysis based on integrating gene expression as mediator with genomic variants.

Comput Biol Med 2016 10 31;77:231-9. Epub 2016 Aug 31.

Bradley Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA 22203, USA. Electronic address:

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http://dx.doi.org/10.1016/j.compbiomed.2016.08.020DOI Listing
October 2016

No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis.

Sci Rep 2016 10 12;6:35278. Epub 2016 Oct 12.

Institut für Medizinische Biometrie und Statistik, Universität zu Lübeck, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Lübeck, Germany.

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http://dx.doi.org/10.1038/srep35278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059659PMC
October 2016

Vitamin B-12 status and neurologic function in older people: a cross-sectional analysis of baseline trial data from the Older People and Enhanced Neurological Function (OPEN) study.

Am J Clin Nutr 2016 Sep 17;104(3):790-6. Epub 2016 Aug 17.

Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, United Kingdom;

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http://dx.doi.org/10.3945/ajcn.116.137927DOI Listing
September 2016

SPRY1 regulates mammary epithelial morphogenesis by modulating EGFR-dependent stromal paracrine signaling and ECM remodeling.

Proc Natl Acad Sci U S A 2016 09 12;113(39):E5731-40. Epub 2016 Sep 12.

School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China;

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047180PMC
http://dx.doi.org/10.1073/pnas.1611532113DOI Listing
September 2016

Uncontrolled Hypertension and Risk of Cardiovascular Mortality in China-Reply.

JAMA Intern Med 2016 08;176(8):1234

Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, England.

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http://dx.doi.org/10.1001/jamainternmed.2016.3825DOI Listing
August 2016

Emerging Risk Factors for Stroke: What Have We Learned From Mendelian Randomization Studies?

Stroke 2016 06 19;47(6):1673-8. Epub 2016 Apr 19.

From the Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1161/STROKEAHA.115.010646DOI Listing
June 2016

Cisplatin selects for stem-like cells in osteosarcoma by activating Notch signaling.

Oncotarget 2016 May;7(22):33055-68

Breast Cancer Now Research Unit, Institute of Cancer Sciences, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.18632/oncotarget.8849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078075PMC
May 2016

A Role for Notch Signalling in Breast Cancer and Endocrine Resistance.

Stem Cells Int 2016 10;2016:2498764. Epub 2016 Jan 10.

Faculty of Life Sciences, University of Manchester, Oxford Road, Manchester M13 9PT, UK.

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http://dx.doi.org/10.1155/2016/2498764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736972PMC
February 2016

Linking autophagy with inflammation through IRF1 signaling in ER+ breast cancer.

Mol Cell Oncol 2016 Jan 14;3(1):e1023928. Epub 2015 Apr 14.

Department of Oncology and Lombardi Comprehensive Cancer Center; Georgetown University Medical Center , Washington, DC USA.

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http://dx.doi.org/10.1080/23723556.2015.1023928DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845173PMC
January 2016