Robert Clarke

Robert Clarke

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Robert Clarke

Publications by authors named "Robert Clarke"

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Maternal obesity increases offspring's mammary cancer recurrence and impairs tumor immune response.

Endocr Relat Cancer 2020 Sep;27(9):469-482

Department of Oncology, Georgetown University, Washington, District of Columbia, USA.

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http://dx.doi.org/10.1530/ERC-20-0065DOI Listing
September 2020

Reproducibility of dietary intakes of macronutrients, specific food groups, and dietary patterns in 211 050 adults in the UK Biobank study.

J Nutr Sci 2019 29;8:e34. Epub 2019 Oct 29.

Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1017/jns.2019.31DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842574PMC
July 2020

debCAM: a bioconductor R package for fully unsupervised deconvolution of complex tissues.

Bioinformatics 2020 Jun;36(12):3927-3929

Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA 22203, USA.

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http://dx.doi.org/10.1093/bioinformatics/btaa205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320609PMC
June 2020

Tobacco smoking and the risk of Parkinson disease: A 65-year follow-up of 30,000 male British doctors.

Neurology 2020 May 5;94(20):e2132-e2138. Epub 2020 May 5.

From the Clinical Trial Service Unit and Epidemiological Studies Unit (B.M.-K., H.P., S.L., J.K., R.G., R.C., R.P.), Nuffield Department of Population Health, University of Oxford; and Medical Research Council Population Health Research Unit (H.P., S.L.), Nuffield Department of Population Health, University of Oxford, United Kingdom.

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http://dx.doi.org/10.1212/WNL.0000000000009437DOI Listing
May 2020

BICORN: An R package for integrative inference of de novo cis-regulatory modules.

Sci Rep 2020 May 14;10(1):7960. Epub 2020 May 14.

Bradley Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, 900 North Glebe Road, Arlington, VA, 22203, USA.

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http://dx.doi.org/10.1038/s41598-020-63043-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224214PMC
May 2020

Red meat, poultry and fish consumption and risk of diabetes: a 9 year prospective cohort study of the China Kadoorie Biobank.

Diabetologia 2020 04 22;63(4):767-779. Epub 2020 Jan 22.

Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Old Road Campus, Oxford, OX3 7LF, UK.

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http://dx.doi.org/10.1007/s00125-020-05091-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054352PMC
April 2020

Mortality and recurrent vascular events after first incident stroke: a 9-year community-based study of 0·5 million Chinese adults.

Lancet Glob Health 2020 04;8(4):e580-e590

Medical Research Council Population Health Research Unit, Oxford, UK; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK. Electronic address:

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http://dx.doi.org/10.1016/S2214-109X(20)30069-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090905PMC
April 2020

Socioeconomic differences in health-care use and outcomes for stroke and ischaemic heart disease in China during 2009-16: a prospective cohort study of 0·5 million adults.

Lancet Glob Health 2020 04;8(4):e591-e602

Health Economics Research Centre, Nuffield Department of Population Health, University of Oxford, Oxford, UK; Institute of Population Health Sciences, Queen Mary University of London, London, UK.

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http://dx.doi.org/10.1016/S2214-109X(20)30078-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090927PMC
April 2020

Validation of Risk Prediction Models to Detect Asymptomatic Carotid Stenosis.

J Am Heart Assoc 2020 Apr 20;9(8):e014766. Epub 2020 Apr 20.

Clinical Trial Service Unit and Epidemiological Studies Unit Nuffield Department of Population Health University of Oxford, United Kingdom.

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http://dx.doi.org/10.1161/JAHA.119.014766DOI Listing
April 2020

Plasma concentrations of vitamin B and folate and global cognitive function in an older population: cross-sectional findings from The Irish Longitudinal Study on Ageing (TILDA).

Br J Nutr 2020 Apr 24:1-9. Epub 2020 Apr 24.

Department of Medical Gerontology, School of Medicine, Trinity College Dublin, Dublin 2, Republic of Ireland.

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http://dx.doi.org/10.1017/S0007114520001427DOI Listing
April 2020

Menopause and risk of hip fracture in middle-aged Chinese women: a 10-year follow-up of China Kadoorie Biobank.

Menopause 2020 03;27(3):311-318

Clinical Trial Service Unit and Epidemiological Studies Unit, University of Oxford, Old Road Campus, Oxford, United Kingdom.

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http://dx.doi.org/10.1097/GME.0000000000001478DOI Listing
March 2020

Sex-Specific Associations of Vascular Risk Factors With Abdominal Aortic Aneurysm: Findings From 1.5 Million Women and 0.8 Million Men in the United States and United Kingdom.

J Am Heart Assoc 2020 Feb 17;9(4):e014748. Epub 2020 Feb 17.

Clinical Trial Service Unit and Epidemiological Studies Unit Nuffield Department of Population Health University of Oxford United Kingdom.

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http://dx.doi.org/10.1161/JAHA.119.014748DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070225PMC
February 2020

The Notch Pathway Promotes Osteosarcoma Progression through Activation of Ephrin Reverse Signaling.

Mol Cancer Res 2019 12 30;17(12):2383-2394. Epub 2019 Sep 30.

Breast Cancer Now Research Unit, Division of Cancer Sciences, University of Manchester, Manchester, United Kingdom.

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http://dx.doi.org/10.1158/1541-7786.MCR-19-0493DOI Listing
December 2019

Vitamin D and Calcium for the Prevention of Fracture: A Systematic Review and Meta-analysis.

JAMA Netw Open 2019 12 2;2(12):e1917789. Epub 2019 Dec 2.

Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1001/jamanetworkopen.2019.17789DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6991219PMC
December 2019

Physical activity, sedentary leisure-time and risk of incident type 2 diabetes: a prospective study of 512 000 Chinese adults.

BMJ Open Diabetes Res Care 2019 18;7(1):e000835. Epub 2019 Dec 18.

Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1136/bmjdrc-2019-000835DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936425PMC
December 2019

Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling.

Nat Commun 2019 11 1;10(1):5016. Epub 2019 Nov 1.

Breast Biology Group, Manchester Breast Centre, Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Wilmslow Road, Manchester, M20 4GJ, UK.

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http://dx.doi.org/10.1038/s41467-019-12807-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825219PMC
November 2019

Development of clinically relevant in vivo metastasis models using human bone discs and breast cancer patient-derived xenografts.

Breast Cancer Res 2019 11 29;21(1):130. Epub 2019 Nov 29.

Department of Oncology and Metabolism, Mellanby Centre for Bone Research, University of Sheffield, Beech Hill Road, Sheffield, S10 2RX, UK.

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http://dx.doi.org/10.1186/s13058-019-1220-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884811PMC
November 2019

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.

Authors:
Brian W Kunkle Benjamin Grenier-Boley Rebecca Sims Joshua C Bis Vincent Damotte Adam C Naj Anne Boland Maria Vronskaya Sven J van der Lee Alexandre Amlie-Wolf Céline Bellenguez Aura Frizatti Vincent Chouraki Eden R Martin Kristel Sleegers Nandini Badarinarayan Johanna Jakobsdottir Kara L Hamilton-Nelson Sonia Moreno-Grau Robert Olaso Rachel Raybould Yuning Chen Amanda B Kuzma Mikko Hiltunen Taniesha Morgan Shahzad Ahmad Badri N Vardarajan Jacques Epelbaum Per Hoffmann Merce Boada Gary W Beecham Jean-Guillaume Garnier Denise Harold Annette L Fitzpatrick Otto Valladares Marie-Laure Moutet Amy Gerrish Albert V Smith Liming Qu Delphine Bacq Nicola Denning Xueqiu Jian Yi Zhao Maria Del Zompo Nick C Fox Seung-Hoan Choi Ignacio Mateo Joseph T Hughes Hieab H Adams John Malamon Florentino Sanchez-Garcia Yogen Patel Jennifer A Brody Beth A Dombroski Maria Candida Deniz Naranjo Makrina Daniilidou Gudny Eiriksdottir Shubhabrata Mukherjee David Wallon James Uphill Thor Aspelund Laura B Cantwell Fabienne Garzia Daniela Galimberti Edith Hofer Mariusz Butkiewicz Bertrand Fin Elio Scarpini Chloe Sarnowski Will S Bush Stéphane Meslage Johannes Kornhuber Charles C White Yuenjoo Song Robert C Barber Sebastiaan Engelborghs Sabrina Sordon Dina Voijnovic Perrie M Adams Rik Vandenberghe Manuel Mayhaus L Adrienne Cupples Marilyn S Albert Peter P De Deyn Wei Gu Jayanadra J Himali Duane Beekly Alessio Squassina Annette M Hartmann Adelina Orellana Deborah Blacker Eloy Rodriguez-Rodriguez Simon Lovestone Melissa E Garcia Rachelle S Doody Carmen Munoz-Fernadez Rebecca Sussams Honghuang Lin Thomas J Fairchild Yolanda A Benito Clive Holmes Hata Karamujić-Čomić Matthew P Frosch Hakan Thonberg Wolfgang Maier Gennady Roshchupkin Bernardino Ghetti Vilmantas Giedraitis Amit Kawalia Shuo Li Ryan M Huebinger Lena Kilander Susanne Moebus Isabel Hernández M Ilyas Kamboh RoseMarie Brundin James Turton Qiong Yang Mindy J Katz Letizia Concari Jenny Lord Alexa S Beiser C Dirk Keene Seppo Helisalmi Iwona Kloszewska Walter A Kukull Anne Maria Koivisto Aoibhinn Lynch Lluís Tarraga Eric B Larson Annakaisa Haapasalo Brian Lawlor Thomas H Mosley Richard B Lipton Vincenzo Solfrizzi Michael Gill W T Longstreth Thomas J Montine Vincenza Frisardi Monica Diez-Fairen Fernando Rivadeneira Ronald C Petersen Vincent Deramecourt Ignacio Alvarez Francesca Salani Antonio Ciaramella Eric Boerwinkle Eric M Reiman Nathalie Fievet Jerome I Rotter Joan S Reisch Olivier Hanon Chiara Cupidi A G Andre Uitterlinden Donald R Royall Carole Dufouil Raffaele Giovanni Maletta Itziar de Rojas Mary Sano Alexis Brice Roberta Cecchetti Peter St George-Hyslop Karen Ritchie Magda Tsolaki Debby W Tsuang Bruno Dubois David Craig Chuang-Kuo Wu Hilkka Soininen Despoina Avramidou Roger L Albin Laura Fratiglioni Antonia Germanou Liana G Apostolova Lina Keller Maria Koutroumani Steven E Arnold Francesco Panza Olymbia Gkatzima Sanjay Asthana Didier Hannequin Patrice Whitehead Craig S Atwood Paolo Caffarra Harald Hampel Inés Quintela Ángel Carracedo Lars Lannfelt David C Rubinsztein Lisa L Barnes Florence Pasquier Lutz Frölich Sandra Barral Bernadette McGuinness Thomas G Beach Janet A Johnston James T Becker Peter Passmore Eileen H Bigio Jonathan M Schott Thomas D Bird Jason D Warren Bradley F Boeve Michelle K Lupton James D Bowen Petra Proitsi Adam Boxer John F Powell James R Burke John S K Kauwe Jeffrey M Burns Michelangelo Mancuso Joseph D Buxbaum Ubaldo Bonuccelli Nigel J Cairns Andrew McQuillin Chuanhai Cao Gill Livingston Chris S Carlson Nicholas J Bass Cynthia M Carlsson John Hardy Regina M Carney Jose Bras Minerva M Carrasquillo Rita Guerreiro Mariet Allen Helena C Chui Elizabeth Fisher Carlo Masullo Elizabeth A Crocco Charles DeCarli Gina Bisceglio Malcolm Dick Li Ma Ranjan Duara Neill R Graff-Radford Denis A Evans Angela Hodges Kelley M Faber Martin Scherer Kenneth B Fallon Matthias Riemenschneider David W Fardo Reinhard Heun Martin R Farlow Heike Kölsch Steven Ferris Markus Leber Tatiana M Foroud Isabella Heuser Douglas R Galasko Ina Giegling Marla Gearing Michael Hüll Daniel H Geschwind John R Gilbert John Morris Robert C Green Kevin Mayo John H Growdon Thomas Feulner Ronald L Hamilton Lindy E Harrell Dmitriy Drichel Lawrence S Honig Thomas D Cushion Matthew J Huentelman Paul Hollingworth Christine M Hulette Bradley T Hyman Rachel Marshall Gail P Jarvik Alun Meggy Erin Abner Georgina E Menzies Lee-Way Jin Ganna Leonenko Luis M Real Gyungah R Jun Clinton T Baldwin Detelina Grozeva Anna Karydas Giancarlo Russo Jeffrey A Kaye Ronald Kim Frank Jessen Neil W Kowall Bruno Vellas Joel H Kramer Emma Vardy Frank M LaFerla Karl-Heinz Jöckel James J Lah Martin Dichgans James B Leverenz David Mann Allan I Levey Stuart Pickering-Brown Andrew P Lieberman Norman Klopp Kathryn L Lunetta H-Erich Wichmann Constantine G Lyketsos Kevin Morgan Daniel C Marson Kristelle Brown Frank Martiniuk Christopher Medway Deborah C Mash Markus M Nöthen Eliezer Masliah Nigel M Hooper Wayne C McCormick Antonio Daniele Susan M McCurry Anthony Bayer Andrew N McDavid John Gallacher Ann C McKee Hendrik van den Bussche Marsel Mesulam Carol Brayne Bruce L Miller Steffi Riedel-Heller Carol A Miller Joshua W Miller Ammar Al-Chalabi John C Morris Christopher E Shaw Amanda J Myers Jens Wiltfang Sid O'Bryant John M Olichney Victoria Alvarez Joseph E Parisi Andrew B Singleton Henry L Paulson John Collinge William R Perry Simon Mead Elaine Peskind David H Cribbs Martin Rossor Aimee Pierce Natalie S Ryan Wayne W Poon Benedetta Nacmias Huntington Potter Sandro Sorbi Joseph F Quinn Eleonora Sacchinelli Ashok Raj Gianfranco Spalletta Murray Raskind Carlo Caltagirone Paola Bossù Maria Donata Orfei Barry Reisberg Robert Clarke Christiane Reitz A David Smith John M Ringman Donald Warden Erik D Roberson Gordon Wilcock Ekaterina Rogaeva Amalia Cecilia Bruni Howard J Rosen Maura Gallo Roger N Rosenberg Yoav Ben-Shlomo Mark A Sager Patrizia Mecocci Andrew J Saykin Pau Pastor Michael L Cuccaro Jeffery M Vance Julie A Schneider Lori S Schneider Susan Slifer William W Seeley Amanda G Smith Joshua A Sonnen Salvatore Spina Robert A Stern Russell H Swerdlow Mitchell Tang Rudolph E Tanzi John Q Trojanowski Juan C Troncoso Vivianna M Van Deerlin Linda J Van Eldik Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Kirk C Wilhelmsen Jennifer Williamson Thomas S Wingo Randall L Woltjer Clinton B Wright Chang-En Yu Lei Yu Yasaman Saba Alberto Pilotto Maria J Bullido Oliver Peters Paul K Crane David Bennett Paola Bosco Eliecer Coto Virginia Boccardi Phil L De Jager Alberto Lleo Nick Warner Oscar L Lopez Martin Ingelsson Panagiotis Deloukas Carlos Cruchaga Caroline Graff Rhian Gwilliam Myriam Fornage Alison M Goate Pascual Sanchez-Juan Patrick G Kehoe Najaf Amin Nilifur Ertekin-Taner Claudine Berr Stéphanie Debette Seth Love Lenore J Launer Steven G Younkin Jean-Francois Dartigues Chris Corcoran M Arfan Ikram Dennis W Dickson Gael Nicolas Dominique Campion JoAnn Tschanz Helena Schmidt Hakon Hakonarson Jordi Clarimon Ron Munger Reinhold Schmidt Lindsay A Farrer Christine Van Broeckhoven Michael C O'Donovan Anita L DeStefano Lesley Jones Jonathan L Haines Jean-Francois Deleuze Michael J Owen Vilmundur Gudnason Richard Mayeux Valentina Escott-Price Bruce M Psaty Alfredo Ramirez Li-San Wang Agustin Ruiz Cornelia M van Duijn Peter A Holmans Sudha Seshadri Julie Williams Phillippe Amouyel Gerard D Schellenberg Jean-Charles Lambert Margaret A Pericak-Vance

Nat Genet 2019 Sep;51(9):1423-1424

John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.

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http://dx.doi.org/10.1038/s41588-019-0495-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265117PMC
September 2019

Physical Activity, Sedentary Leisure Time, Circulating Metabolic Markers, and Risk of Major Vascular Diseases.

Circ Genom Precis Med 2019 09 28;12(9):386-396. Epub 2019 Aug 28.

Clinical Trial Service Unit and Epidemiological Studies Unit (Y.P., C.K., H.D., I.Y.M., Y.C., L.Y., R.W., F.B., R.P., R. Clarke, R. Collins, D.A.B., L.L., M.V.H., Z.C.), Nuffield Department of Population Health, University of Oxford, United Kingdom.

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http://dx.doi.org/10.1161/CIRCGEN.118.002527DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752700PMC
September 2019

Risks of ischaemic heart disease and stroke in meat eaters, fish eaters, and vegetarians over 18 years of follow-up: results from the prospective EPIC-Oxford study.

BMJ 2019 09 4;366:l4897. Epub 2019 Sep 4.

Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Richard Doll Building, Oxford OX3 7LF, UK.

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http://dx.doi.org/10.1136/bmj.l4897DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724406PMC
September 2019

The Milk Protein Alpha-Casein Suppresses Triple Negative Breast Cancer Stem Cell Activity Via STAT and HIF-1alpha Signalling Pathways in Breast Cancer Cells and Fibroblasts.

J Mammary Gland Biol Neoplasia 2019 09 12;24(3):245-256. Epub 2019 Sep 12.

Breast Biology Group, Breast Cancer Now Research Unit, Division of Cancer Sciences, Manchester Cancer Research Centre, University of Manchester, Manchester, M20 4GJ, UK.

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http://dx.doi.org/10.1007/s10911-019-09435-1DOI Listing
September 2019

On-Board Real-Time Trajectory Planning for Fixed Wing Unmanned Aerial Vehicles in Extreme Environments.

Sensors (Basel) 2019 Sep 21;19(19). Epub 2019 Sep 21.

School of Earth Sciences, University of Bristol, Bristol BS8 1RJ, UK.

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http://dx.doi.org/10.3390/s19194085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6806282PMC
September 2019

PAK4 regulates stemness and progression in endocrine resistant ER-positive metastatic breast cancer.

Cancer Lett 2019 08 20;458:66-75. Epub 2019 May 20.

Breast Biology Group, Manchester Breast Centre, Division of Cancer Sciences, Oglesby Cancer Research Building, University of Manchester, Manchester, M20 4GJ, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2019.05.014DOI Listing
August 2019

Carotid Intima-Media Thickness but Not Carotid Artery Plaque in Healthy Individuals Is Linked to Lean Body Mass.

J Am Heart Assoc 2019 08 31;8(15):e011919. Epub 2019 Jul 31.

Clinical Trial Service Unit and Epidemiological Studies Unit Nuffield Department of Population Health University of Oxford Oxford United Kingdom.

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http://dx.doi.org/10.1161/JAHA.118.011919DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761650PMC
August 2019

Glutamine Metabolism Drives Growth in Advanced Hormone Receptor Positive Breast Cancer.

Front Oncol 2019 2;9:686. Epub 2019 Aug 2.

Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, United States.

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http://dx.doi.org/10.3389/fonc.2019.00686DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688514PMC
August 2019

RNA interference screening methods to identify proliferation determinants and mechanisms of resistance to immune attack.

Methods Enzymol 2020 3;636:299-322. Epub 2019 Jul 3.

Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, United States. Electronic address:

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http://dx.doi.org/10.1016/bs.mie.2019.06.002DOI Listing
July 2019

Systems biology: perspectives on multiscale modeling in research on endocrine-related cancers.

Endocr Relat Cancer 2019 06;26(6):R345-R368

Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, Virginia, USA.

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http://dx.doi.org/10.1530/ERC-18-0309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045974PMC
June 2019

Beneficial Effects of Milk Consumption on Lean Body Mass.

Authors:
Robert Clarke

Clin Chem 2019 06;65(6):718-719

Clinical Trial Service Unit and Epidemiological Studies Unit, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1373/clinchem.2019.305581DOI Listing
June 2019

Targeting Endometrial Cancer Stem Cell Activity with Metformin Is Inhibited by Patient-Derived Adipocyte-Secreted Factors.

Cancers (Basel) 2019 May 11;11(5). Epub 2019 May 11.

Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester M13 9WL, UK.

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http://dx.doi.org/10.3390/cancers11050653DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562824PMC
May 2019

Assessment of the Role of Carotid Atherosclerosis in the Association Between Major Cardiovascular Risk Factors and Ischemic Stroke Subtypes.

JAMA Netw Open 2019 05 3;2(5):e194873. Epub 2019 May 3.

Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1001/jamanetworkopen.2019.4873DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547114PMC
May 2019

Estrogen-Induced Apoptosis in Breast Cancers Is Phenocopied by Blocking Dephosphorylation of Eukaryotic Initiation Factor 2 Alpha (eIF2α) Protein.

Mol Cancer Res 2019 04 17;17(4):918-928. Epub 2019 Jan 17.

Department of Oncology, Georgetown-Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington D.C.

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http://dx.doi.org/10.1158/1541-7786.MCR-18-0481DOI Listing
April 2019

Cardiovascular risk factors and Parkinson's disease in 500,000 Chinese adults.

Ann Clin Transl Neurol 2019 Apr 10;6(4):624-632. Epub 2019 Mar 10.

Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU) Nuffield Department of Population Health University of Oxford Oxford United Kingdom.

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http://dx.doi.org/10.1002/acn3.732DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469341PMC
April 2019

Adiposity in middle and old age and risk of death from dementia: 40-year follow-up of 19,000 men in the Whitehall study.

Age Ageing 2019 03;48(2):247-253

Faculty of Epidemiology and Population Health, Department of Community Medicine, London School of Hygiene and Tropical Medicine and Adjunct Professor of Epidemiology, UiT the Arctic University of Norway, Tromsø, Norway.

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http://dx.doi.org/10.1093/ageing/afy182DOI Listing
March 2019

Relative effects of LDL-C on ischemic stroke and coronary disease: A Mendelian randomization study.

Neurology 2019 03 20;92(11):e1176-e1187. Epub 2019 Feb 20.

From the Clinical Trial Service Unit and Epidemiological Studies Unit (E.V.-M., S.P., R.C., T.S., J.C.H.) and MRC Population Health Research Unit (S.P.), Nuffield Department of Population Health, University of Oxford, UK; and Departments of Neurology and Public Health Sciences (B.B.W.), University of Virginia School of Medicine, Charlottesville, VA.

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http://dx.doi.org/10.1212/WNL.0000000000007091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511103PMC
March 2019

Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.

Authors:
Brian W Kunkle Benjamin Grenier-Boley Rebecca Sims Joshua C Bis Vincent Damotte Adam C Naj Anne Boland Maria Vronskaya Sven J van der Lee Alexandre Amlie-Wolf Céline Bellenguez Aura Frizatti Vincent Chouraki Eden R Martin Kristel Sleegers Nandini Badarinarayan Johanna Jakobsdottir Kara L Hamilton-Nelson Sonia Moreno-Grau Robert Olaso Rachel Raybould Yuning Chen Amanda B Kuzma Mikko Hiltunen Taniesha Morgan Shahzad Ahmad Badri N Vardarajan Jacques Epelbaum Per Hoffmann Merce Boada Gary W Beecham Jean-Guillaume Garnier Denise Harold Annette L Fitzpatrick Otto Valladares Marie-Laure Moutet Amy Gerrish Albert V Smith Liming Qu Delphine Bacq Nicola Denning Xueqiu Jian Yi Zhao Maria Del Zompo Nick C Fox Seung-Hoan Choi Ignacio Mateo Joseph T Hughes Hieab H Adams John Malamon Florentino Sanchez-Garcia Yogen Patel Jennifer A Brody Beth A Dombroski Maria Candida Deniz Naranjo Makrina Daniilidou Gudny Eiriksdottir Shubhabrata Mukherjee David Wallon James Uphill Thor Aspelund Laura B Cantwell Fabienne Garzia Daniela Galimberti Edith Hofer Mariusz Butkiewicz Bertrand Fin Elio Scarpini Chloe Sarnowski Will S Bush Stéphane Meslage Johannes Kornhuber Charles C White Yuenjoo Song Robert C Barber Sebastiaan Engelborghs Sabrina Sordon Dina Voijnovic Perrie M Adams Rik Vandenberghe Manuel Mayhaus L Adrienne Cupples Marilyn S Albert Peter P De Deyn Wei Gu Jayanadra J Himali Duane Beekly Alessio Squassina Annette M Hartmann Adelina Orellana Deborah Blacker Eloy Rodriguez-Rodriguez Simon Lovestone Melissa E Garcia Rachelle S Doody Carmen Munoz-Fernadez Rebecca Sussams Honghuang Lin Thomas J Fairchild Yolanda A Benito Clive Holmes Hata Karamujić-Čomić Matthew P Frosch Hakan Thonberg Wolfgang Maier Gennady Roshchupkin Bernardino Ghetti Vilmantas Giedraitis Amit Kawalia Shuo Li Ryan M Huebinger Lena Kilander Susanne Moebus Isabel Hernández M Ilyas Kamboh RoseMarie Brundin James Turton Qiong Yang Mindy J Katz Letizia Concari Jenny Lord Alexa S Beiser C Dirk Keene Seppo Helisalmi Iwona Kloszewska Walter A Kukull Anne Maria Koivisto Aoibhinn Lynch Lluís Tarraga Eric B Larson Annakaisa Haapasalo Brian Lawlor Thomas H Mosley Richard B Lipton Vincenzo Solfrizzi Michael Gill W T Longstreth Thomas J Montine Vincenza Frisardi Monica Diez-Fairen Fernando Rivadeneira Ronald C Petersen Vincent Deramecourt Ignacio Alvarez Francesca Salani Antonio Ciaramella Eric Boerwinkle Eric M Reiman Nathalie Fievet Jerome I Rotter Joan S Reisch Olivier Hanon Chiara Cupidi A G Andre Uitterlinden Donald R Royall Carole Dufouil Raffaele Giovanni Maletta Itziar de Rojas Mary Sano Alexis Brice Roberta Cecchetti Peter St George-Hyslop Karen Ritchie Magda Tsolaki Debby W Tsuang Bruno Dubois David Craig Chuang-Kuo Wu Hilkka Soininen Despoina Avramidou Roger L Albin Laura Fratiglioni Antonia Germanou Liana G Apostolova Lina Keller Maria Koutroumani Steven E Arnold Francesco Panza Olymbia Gkatzima Sanjay Asthana Didier Hannequin Patrice Whitehead Craig S Atwood Paolo Caffarra Harald Hampel Inés Quintela Ángel Carracedo Lars Lannfelt David C Rubinsztein Lisa L Barnes Florence Pasquier Lutz Frölich Sandra Barral Bernadette McGuinness Thomas G Beach Janet A Johnston James T Becker Peter Passmore Eileen H Bigio Jonathan M Schott Thomas D Bird Jason D Warren Bradley F Boeve Michelle K Lupton James D Bowen Petra Proitsi Adam Boxer John F Powell James R Burke John S K Kauwe Jeffrey M Burns Michelangelo Mancuso Joseph D Buxbaum Ubaldo Bonuccelli Nigel J Cairns Andrew McQuillin Chuanhai Cao Gill Livingston Chris S Carlson Nicholas J Bass Cynthia M Carlsson John Hardy Regina M Carney Jose Bras Minerva M Carrasquillo Rita Guerreiro Mariet Allen Helena C Chui Elizabeth Fisher Carlo Masullo Elizabeth A Crocco Charles DeCarli Gina Bisceglio Malcolm Dick Li Ma Ranjan Duara Neill R Graff-Radford Denis A Evans Angela Hodges Kelley M Faber Martin Scherer Kenneth B Fallon Matthias Riemenschneider David W Fardo Reinhard Heun Martin R Farlow Heike Kölsch Steven Ferris Markus Leber Tatiana M Foroud Isabella Heuser Douglas R Galasko Ina Giegling Marla Gearing Michael Hüll Daniel H Geschwind John R Gilbert John Morris Robert C Green Kevin Mayo John H Growdon Thomas Feulner Ronald L Hamilton Lindy E Harrell Dmitriy Drichel Lawrence S Honig Thomas D Cushion Matthew J Huentelman Paul Hollingworth Christine M Hulette Bradley T Hyman Rachel Marshall Gail P Jarvik Alun Meggy Erin Abner Georgina E Menzies Lee-Way Jin Ganna Leonenko Luis M Real Gyungah R Jun Clinton T Baldwin Detelina Grozeva Anna Karydas Giancarlo Russo Jeffrey A Kaye Ronald Kim Frank Jessen Neil W Kowall Bruno Vellas Joel H Kramer Emma Vardy Frank M LaFerla Karl-Heinz Jöckel James J Lah Martin Dichgans James B Leverenz David Mann Allan I Levey Stuart Pickering-Brown Andrew P Lieberman Norman Klopp Kathryn L Lunetta H-Erich Wichmann Constantine G Lyketsos Kevin Morgan Daniel C Marson Kristelle Brown Frank Martiniuk Christopher Medway Deborah C Mash Markus M Nöthen Eliezer Masliah Nigel M Hooper Wayne C McCormick Antonio Daniele Susan M McCurry Anthony Bayer Andrew N McDavid John Gallacher Ann C McKee Hendrik van den Bussche Marsel Mesulam Carol Brayne Bruce L Miller Steffi Riedel-Heller Carol A Miller Joshua W Miller Ammar Al-Chalabi John C Morris Christopher E Shaw Amanda J Myers Jens Wiltfang Sid O'Bryant John M Olichney Victoria Alvarez Joseph E Parisi Andrew B Singleton Henry L Paulson John Collinge William R Perry Simon Mead Elaine Peskind David H Cribbs Martin Rossor Aimee Pierce Natalie S Ryan Wayne W Poon Benedetta Nacmias Huntington Potter Sandro Sorbi Joseph F Quinn Eleonora Sacchinelli Ashok Raj Gianfranco Spalletta Murray Raskind Carlo Caltagirone Paola Bossù Maria Donata Orfei Barry Reisberg Robert Clarke Christiane Reitz A David Smith John M Ringman Donald Warden Erik D Roberson Gordon Wilcock Ekaterina Rogaeva Amalia Cecilia Bruni Howard J Rosen Maura Gallo Roger N Rosenberg Yoav Ben-Shlomo Mark A Sager Patrizia Mecocci Andrew J Saykin Pau Pastor Michael L Cuccaro Jeffery M Vance Julie A Schneider Lori S Schneider Susan Slifer William W Seeley Amanda G Smith Joshua A Sonnen Salvatore Spina Robert A Stern Russell H Swerdlow Mitchell Tang Rudolph E Tanzi John Q Trojanowski Juan C Troncoso Vivianna M Van Deerlin Linda J Van Eldik Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Kirk C Wilhelmsen Jennifer Williamson Thomas S Wingo Randall L Woltjer Clinton B Wright Chang-En Yu Lei Yu Yasaman Saba Alberto Pilotto Maria J Bullido Oliver Peters Paul K Crane David Bennett Paola Bosco Eliecer Coto Virginia Boccardi Phil L De Jager Alberto Lleo Nick Warner Oscar L Lopez Martin Ingelsson Panagiotis Deloukas Carlos Cruchaga Caroline Graff Rhian Gwilliam Myriam Fornage Alison M Goate Pascual Sanchez-Juan Patrick G Kehoe Najaf Amin Nilifur Ertekin-Taner Claudine Berr Stéphanie Debette Seth Love Lenore J Launer Steven G Younkin Jean-Francois Dartigues Chris Corcoran M Arfan Ikram Dennis W Dickson Gael Nicolas Dominique Campion JoAnn Tschanz Helena Schmidt Hakon Hakonarson Jordi Clarimon Ron Munger Reinhold Schmidt Lindsay A Farrer Christine Van Broeckhoven Michael C O'Donovan Anita L DeStefano Lesley Jones Jonathan L Haines Jean-Francois Deleuze Michael J Owen Vilmundur Gudnason Richard Mayeux Valentina Escott-Price Bruce M Psaty Alfredo Ramirez Li-San Wang Agustin Ruiz Cornelia M van Duijn Peter A Holmans Sudha Seshadri Julie Williams Phillippe Amouyel Gerard D Schellenberg Jean-Charles Lambert Margaret A Pericak-Vance

Nat Genet 2019 03 28;51(3):414-430. Epub 2019 Feb 28.

John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.

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http://dx.doi.org/10.1038/s41588-019-0358-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463297PMC
March 2019

Blood Pressure and Risk of Subarachnoid Hemorrhage in China.

Stroke 2018 Dec 7:STROKEAHA118022239. Epub 2018 Dec 7.

From the Nuffield Department of Population Health, University of Oxford, United Kingdom (I.J.M., R.C., B.L., X.L.K., Z.C., Y.C., S.L.).

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http://dx.doi.org/10.1161/STROKEAHA.118.022239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314500PMC
December 2018

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.

Authors:
Symen Ligthart Ahmad Vaez Urmo Võsa Maria G Stathopoulou Paul S de Vries Bram P Prins Peter J Van der Most Toshiko Tanaka Elnaz Naderi Lynda M Rose Ying Wu Robert Karlsson Maja Barbalic Honghuang Lin René Pool Gu Zhu Aurélien Macé Carlo Sidore Stella Trompet Massimo Mangino Maria Sabater-Lleal John P Kemp Ali Abbasi Tim Kacprowski Niek Verweij Albert V Smith Tao Huang Carola Marzi Mary F Feitosa Kurt K Lohman Marcus E Kleber Yuri Milaneschi Christian Mueller Mahmudul Huq Efthymia Vlachopoulou Leo-Pekka Lyytikäinen Christopher Oldmeadow Joris Deelen Markus Perola Jing Hua Zhao Bjarke Feenstra Marzyeh Amini Jari Lahti Katharina E Schraut Myriam Fornage Bhoom Suktitipat Wei-Min Chen Xiaohui Li Teresa Nutile Giovanni Malerba Jian'an Luan Tom Bak Nicholas Schork Fabiola Del Greco M Elisabeth Thiering Anubha Mahajan Riccardo E Marioni Evelin Mihailov Joel Eriksson Ayse Bilge Ozel Weihua Zhang Maria Nethander Yu-Ching Cheng Stella Aslibekyan Wei Ang Ilaria Gandin Loïc Yengo Laura Portas Charles Kooperberg Edith Hofer Kumar B Rajan Claudia Schurmann Wouter den Hollander Tarunveer S Ahluwalia Jing Zhao Harmen H M Draisma Ian Ford Nicholas Timpson Alexander Teumer Hongyan Huang Simone Wahl YongMei Liu Jie Huang Hae-Won Uh Frank Geller Peter K Joshi Lisa R Yanek Elisabetta Trabetti Benjamin Lehne Diego Vozzi Marie Verbanck Ginevra Biino Yasaman Saba Ingrid Meulenbelt Jeff R O'Connell Markku Laakso Franco Giulianini Patrik K E Magnusson Christie M Ballantyne Jouke Jan Hottenga Grant W Montgomery Fernando Rivadineira Rico Rueedi Maristella Steri Karl-Heinz Herzig David J Stott Cristina Menni Mattias Frånberg Beate St Pourcain Stephan B Felix Tune H Pers Stephan J L Bakker Peter Kraft Annette Peters Dhananjay Vaidya Graciela Delgado Johannes H Smit Vera Großmann Juha Sinisalo Ilkka Seppälä Stephen R Williams Elizabeth G Holliday Matthijs Moed Claudia Langenberg Katri Räikkönen Jingzhong Ding Harry Campbell Michele M Sale Yii-Der I Chen Alan L James Daniela Ruggiero Nicole Soranzo Catharina A Hartman Erin N Smith Gerald S Berenson Christian Fuchsberger Dena Hernandez Carla M T Tiesler Vilmantas Giedraitis David Liewald Krista Fischer Dan Mellström Anders Larsson Yunmei Wang William R Scott Matthias Lorentzon John Beilby Kathleen A Ryan Craig E Pennell Dragana Vuckovic Beverly Balkau Maria Pina Concas Reinhold Schmidt Carlos F Mendes de Leon Erwin P Bottinger Margreet Kloppenburg Lavinia Paternoster Michael Boehnke A W Musk Gonneke Willemsen David M Evans Pamela A F Madden Mika Kähönen Zoltán Kutalik Magdalena Zoledziewska Ville Karhunen Stephen B Kritchevsky Naveed Sattar Genevieve Lachance Robert Clarke Tamara B Harris Olli T Raitakari John R Attia Diana van Heemst Eero Kajantie Rossella Sorice Giovanni Gambaro Robert A Scott Andrew A Hicks Luigi Ferrucci Marie Standl Cecilia M Lindgren John M Starr Magnus Karlsson Lars Lind Jun Z Li John C Chambers Trevor A Mori Eco J C N de Geus Andrew C Heath Nicholas G Martin Juha Auvinen Brendan M Buckley Anton J M de Craen Melanie Waldenberger Konstantin Strauch Thomas Meitinger Rodney J Scott Mark McEvoy Marian Beekman Cristina Bombieri Paul M Ridker Karen L Mohlke Nancy L Pedersen Alanna C Morrison Dorret I Boomsma John B Whitfield David P Strachan Albert Hofman Peter Vollenweider Francesco Cucca Marjo-Riitta Jarvelin J Wouter Jukema Tim D Spector Anders Hamsten Tanja Zeller André G Uitterlinden Matthias Nauck Vilmundur Gudnason Lu Qi Harald Grallert Ingrid B Borecki Jerome I Rotter Winfried März Philipp S Wild Marja-Liisa Lokki Michael Boyle Veikko Salomaa Mads Melbye Johan G Eriksson James F Wilson Brenda W J H Penninx Diane M Becker Bradford B Worrall Greg Gibson Ronald M Krauss Marina Ciullo Gianluigi Zaza Nicholas J Wareham Albertine J Oldehinkel Lyle J Palmer Sarah S Murray Peter P Pramstaller Stefania Bandinelli Joachim Heinrich Erik Ingelsson Ian J Deary Reedik Mägi Liesbeth Vandenput Pim van der Harst Karl C Desch Jaspal S Kooner Claes Ohlsson Caroline Hayward Terho Lehtimäki Alan R Shuldiner Donna K Arnett Lawrence J Beilin Antonietta Robino Philippe Froguel Mario Pirastu Tine Jess Wolfgang Koenig Ruth J F Loos Denis A Evans Helena Schmidt George Davey Smith P Eline Slagboom Gudny Eiriksdottir Andrew P Morris Bruce M Psaty Russell P Tracy Ilja M Nolte Eric Boerwinkle Sophie Visvikis-Siest Alex P Reiner Myron Gross Joshua C Bis Lude Franke Oscar H Franco Emelia J Benjamin Daniel I Chasman Josée Dupuis Harold Snieder Abbas Dehghan Behrooz Z Alizadeh

Am J Hum Genet 2018 11;103(5):691-706

Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2018.09.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218410PMC
November 2018

Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

Nat Commun 2018 11 28;9(1):5052. Epub 2018 Nov 28.

Medical Genomics Center, National Center for Global Health and Medicine, Tokyo, 162-8655, Japan.

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http://dx.doi.org/10.1038/s41467-018-07345-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261994PMC
November 2018

Autophagy and unfolded protein response (UPR) regulate mammary gland involution by restraining apoptosis-driven irreversible changes.

Cell Death Discov 2018 15;4:40. Epub 2018 Oct 15.

1Department of Oncology and Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057 USA.

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http://dx.doi.org/10.1038/s41420-018-0105-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186758PMC
October 2018

Questioning the Associations of ω-3 Fatty Acid Supplement Use With Cardiovascular Disease Risks-Reply.

JAMA Cardiol 2018 08;3(8):781-782

Clinical Trial Service Unit, Nuffield Department of Population Health, University of Oxford, Oxford, England.

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http://dx.doi.org/10.1001/jamacardio.2018.1312DOI Listing
August 2018

Ethnicity influences breast cancer stem cells' drug resistance.

Breast J 2018 07 2;24(4):701-703. Epub 2018 Mar 2.

Breast Biology Group, Division of Molecular and Clinical Cancer Sciences, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1111/tbj.13021DOI Listing
July 2018

Blastocyst development rate influences implantation and live birth rates of similarly graded euploid blastocysts.

Fertil Steril 2018 07 13;110(1):95-102.e1. Epub 2018 Jun 13.

Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medicine, New York, New York 10021.

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http://dx.doi.org/10.1016/j.fertnstert.2018.03.032DOI Listing
July 2018

Genomic Response to Vitamin D Supplementation in the Setting of a Randomized, Placebo-Controlled Trial.

EBioMedicine 2018 May 10;31:133-142. Epub 2018 Apr 10.

Wellcome Centre for Human Genetics (WHG), Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2018.04.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013786PMC
May 2018

Lack of genetic support for shared aetiology of Coronary Artery Disease and Late-onset Alzheimer's disease.

Sci Rep 2018 05 8;8(1):7102. Epub 2018 May 8.

Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1038/s41598-018-25460-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940751PMC
May 2018

Smoking and smoking cessation in relation to risk of diabetes in Chinese men and women: a 9-year prospective study of 0·5 million people.

Lancet Public Health 2018 04 13;3(4):e167-e176. Epub 2018 Mar 13.

Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK. Electronic address:

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http://dx.doi.org/10.1016/S2468-2667(18)30026-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887081PMC
April 2018

Estrogenicity of essential oils is not required to relieve symptoms of urogenital atrophy in breast cancer survivors.

Ther Adv Med Oncol 2018 2;10:1758835918766189. Epub 2018 Apr 2.

Breast Cancer Now Research Unit, Division of Cancer Sciences, University of Manchester, Manchester Cancer Research Centre, 555 Wilmslow Road, Manchester M20 4GJ, UK.

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http://dx.doi.org/10.1177/1758835918766189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5888815PMC
April 2018

Plasma cytokines and risk of coronary heart disease in the PROCARDIS study.

Open Heart 2018 25;5(1):e000807. Epub 2018 Apr 25.

Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1136/openhrt-2018-000807DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922567PMC
April 2018

The Role of Steroid Hormones in Breast and Effects on Cancer Stem Cells.

Curr Stem Cell Rep 2018 13;4(1):81-94. Epub 2018 Mar 13.

Breast Biology Group, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine, and Health, Manchester Cancer Research Centre, Wilmslow Road, Manchester, M20 4GJ UK.

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http://dx.doi.org/10.1007/s40778-018-0114-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866269PMC
March 2018

Lipids, Lipoproteins, and Metabolites and Risk of Myocardial Infarction and Stroke.

J Am Coll Cardiol 2018 02;71(6):620-632

Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2017.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811927PMC
February 2018

Patterns and management of chronic obstructive pulmonary disease in urban and rural China: a community-based survey of 25 000 adults across 10 regions.

BMJ Open Respir Res 2018 19;5(1):e000267. Epub 2018 Feb 19.

Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1136/bmjresp-2017-000267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844384PMC
February 2018

SparseIso: a novel Bayesian approach to identify alternatively spliced isoforms from RNA-seq data.

Bioinformatics 2018 01;34(1):56-63

Bradley Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA 22203, USA.

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http://dx.doi.org/10.1093/bioinformatics/btx557DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870564PMC
January 2018

Association of Physical Activity With Risk of Major Cardiovascular Diseases in Chinese Men and Women.

JAMA Cardiol 2017 12;2(12):1349-1358

Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, England.

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http://dx.doi.org/10.1001/jamacardio.2017.4069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814992PMC
December 2017

GPER mediates the angiocrine actions induced by IGF1 through the HIF-1α/VEGF pathway in the breast tumor microenvironment.

Breast Cancer Res 2017 Dec 6;19(1):129. Epub 2017 Dec 6.

Breast Cancer Now Research Unit, Division of Cancer Sciences, Manchester Cancer Research Centre, University of Manchester, Wilmslow Road, Manchester, M204GJ, UK.

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http://dx.doi.org/10.1186/s13058-017-0923-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719673PMC
December 2017

G Protein-Coupled Receptors at the Crossroad between Physiologic and Pathologic Angiogenesis: Old Paradigms and Emerging Concepts.

Int J Mol Sci 2017 Dec 14;18(12). Epub 2017 Dec 14.

Department of Pharmacy, Health and Nutrition Sciences, University of Calabria via Savinio, 87036 Rende, Italy.

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http://dx.doi.org/10.3390/ijms18122713DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751314PMC
December 2017

EGR1 regulates cellular metabolism and survival in endocrine resistant breast cancer.

Oncotarget 2017 Nov 30;8(57):96865-96884. Epub 2017 May 30.

Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, USA.

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http://dx.doi.org/10.18632/oncotarget.18292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722529PMC
November 2017

Effects of Vitamin D on Blood Pressure, Arterial Stiffness, and Cardiac Function in Older People After 1 Year: BEST-D (Biochemical Efficacy and Safety Trial of Vitamin D).

J Am Heart Assoc 2017 Oct 24;6(10). Epub 2017 Oct 24.

Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, United Kingdom

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http://dx.doi.org/10.1161/JAHA.117.005707DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721827PMC
October 2017

Breast cancer cell obatoclax response characterization using passivated-electrode insulator-based dielectrophoresis.

Electrophoresis 2017 08 5;38(16):1988-1995. Epub 2017 Jul 5.

VT MEMS Lab, The Bradley Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Blacksburg, VA, USA.

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http://dx.doi.org/10.1002/elps.201600447DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976885PMC
August 2017

A Replicated, Genome-Wide Significant Association of Aortic Stenosis With a Genetic Variant for Lipoprotein(a): Meta-Analysis of Published and Novel Data.

Circulation 2017 03;135(12):1181-1183

From Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, United Kingdom (B.J.C., R.C.T., J.G.); British Heart Foundation Centre of Research Excellence, University of Oxford, United Kingdom (B.J.C.); Kolling Institute, University of Sydney, Australia (S.C.); Department of Cardiology, Royal North Shore Hospital, Sydney, Australia (S.C.); Guy's and St Thomas' Hospitals, London, United Kingdom (B.P.); Department of Medicine, McGill University, Montreal, QC, Canada (J.C.E., G.T.); McGill University and Genome Quebec Innovation Centre, Montreal, QC, Canada (M.L.); Preventive and Genomic Cardiology, McGill University Health Centre and Research Institute, Montreal, QC, Canada (G.T.); and Clinical Trial Service Unit and Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, United Kingdom (R.C.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.026103DOI Listing
March 2017