Publications by authors named "Robert C Murphy"

100Publications

An improved and highly selective fluorescence assay for measuring phosphatidylserine decarboxylase activity.

J Biol Chem 2020 Jul 19;295(27):9211-9222. Epub 2020 May 19.

Basic Science Section, Department of Medicine, National Jewish Health, Denver, Colorado, USA

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http://dx.doi.org/10.1074/jbc.RA120.013421DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335775PMC
July 2020

Lipid mass spectrometry: A path traveled for 50 years.

Authors:
Robert C Murphy

J Mass Spectrom 2020 May 12;55(5):e4492. Epub 2020 Mar 12.

Department of Pharmacology, University of Colorado Denver, Anschutz Medical Campus, 12801 E. 17th Ave, Aurora, Colorado, 80045.

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http://dx.doi.org/10.1002/jms.4492DOI Listing
May 2020

Overview of Lipid Mass Spectrometry and Lipidomics.

Methods Mol Biol 2019 ;1978:81-105

Department of Pharmacology, University of Colorado Denver, Aurora, CO, USA.

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http://link.springer.com/10.1007/978-1-4939-9236-2_6
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http://dx.doi.org/10.1007/978-1-4939-9236-2_6DOI Listing
November 2019

Challenges in Mass Spectrometry-based Lipidomics of Neutral Lipids.

Authors:
Robert C Murphy

Trends Analyt Chem 2018 Oct 4;107:91-98. Epub 2018 Aug 4.

Department of Pharmacology, University of Colorado Denver, Anschutz Medical Campus, 12801 E. 17 Ave, Aurora, CO 80045.

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http://dx.doi.org/10.1016/j.trac.2018.07.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483396PMC
October 2018

Enzymatically oxidized phospholipids assume center stage as essential regulators of innate immunity and cell death.

Sci Signal 2019 03 26;12(574). Epub 2019 Mar 26.

Department of Internal Medicine 3-Rheumatology and Immunology, University Hospital Erlangen and Friedrich-Alexander University Erlangen-Nuremberg (FAU) 91054, Erlangen, Germany.

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http://dx.doi.org/10.1126/scisignal.aau2293DOI Listing
March 2019

Lysophospholipid acyltransferases and leukotriene biosynthesis: intersection of the Lands cycle and the arachidonate PI cycle.

J Lipid Res 2019 02 3;60(2):219-226. Epub 2019 Jan 3.

Department of Pharmacology, University of Colorado Denver, Aurora, CO 80045.

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http://dx.doi.org/10.1194/jlr.S091371DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358305PMC
February 2019

Enhanced Platelet-Activating Factor Synthesis Facilitates Acute and Delayed Effects of Ethanol-Intoxicated Thermal Burn Injury.

J Invest Dermatol 2018 11 30;138(11):2461-2469. Epub 2018 May 30.

Department of Pharmacology and Toxicology, Wright State University, Dayton, Ohio, USA; Department of Dermatology, Wright State University, Dayton, Ohio, USA; The Dayton VA Medical Center, Dayton, OH. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2018.04.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996586PMC
November 2018

Tandem Mass Spectrometry and Ion Mobility Reveals Structural Insight into Eicosanoid Product Ion Formation.

J Am Soc Mass Spectrom 2018 06 23;29(6):1231-1241. Epub 2018 Apr 23.

Department of Pharmacology, University of Colorado Denver, Mail Stop 8303, 12801 E. 17th Ave, Aurora, CO, 80045, USA.

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http://dx.doi.org/10.1007/s13361-018-1927-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004252PMC
June 2018

Altered eicosanoid production and phospholipid remodeling during cell culture.

J Lipid Res 2018 03 20;59(3):542-549. Epub 2018 Jan 20.

Department of Pharmacology, Anschutz Medical Campus, University of Colorado Denver, Aurora, CO 80045

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http://dx.doi.org/10.1194/jlr.M083030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832926PMC
March 2018

F-FDG PET/CT in Erdheim-Chester Disease: Imaging Findings and Potential BRAF Mutation Biomarker.

J Nucl Med 2018 05 2;59(5):774-779. Epub 2017 Nov 2.

Department of Radiology, Mayo Clinic, Rochester, Minnesota

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http://jnm.snmjournals.org/lookup/doi/10.2967/jnumed.117.200
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http://dx.doi.org/10.2967/jnumed.117.200741DOI Listing
May 2018

Dormant 5-lipoxygenase in inflammatory macrophages is triggered by exogenous arachidonic acid.

Sci Rep 2017 09 8;7(1):10981. Epub 2017 Sep 8.

Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, 14040-903, Brazil.

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http://dx.doi.org/10.1038/s41598-017-11496-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591212PMC
September 2017

Determination of Double Bond Positions in Polyunsaturated Fatty Acids Using the Photochemical Paternò-Büchi Reaction with Acetone and Tandem Mass Spectrometry.

Anal Chem 2017 08 2;89(16):8545-8553. Epub 2017 Aug 2.

Department of Pharmacology, University of Colorado Denver , Anschutz Medical Campus, 12801 E. 17th Ave., Aurora, Colorado 80045, United States.

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http://dx.doi.org/10.1021/acs.analchem.7b02375DOI Listing
August 2017

Lipidomic characterization and localization of phospholipids in the human lung.

J Lipid Res 2017 05 9;58(5):926-933. Epub 2017 Mar 9.

Department of Medicine, National Jewish Health, Denver, CO 80206

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http://dx.doi.org/10.1194/jlr.M074955DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408611PMC
May 2017

The Endocannabinoid Metabolite Prostaglandin E (PGE)-Glycerol Inhibits Human Neutrophil Functions: Involvement of Its Hydrolysis into PGE and EP Receptors.

J Immunol 2017 04 3;198(8):3255-3263. Epub 2017 Mar 3.

Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, Département de Médecine, Faculté de Médecine, Université Laval, Quebec City, Quebec G1V 4G5, Canada; and

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http://dx.doi.org/10.4049/jimmunol.1601767DOI Listing
April 2017

Directing eicosanoid esterification into phospholipids.

J Lipid Res 2017 05 27;58(5):837-839. Epub 2017 Feb 27.

Department of Pharmacology, University of Colorado Denver, Aurora, CO.

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http://dx.doi.org/10.1194/jlr.C075986DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408599PMC
May 2017

DioxolaneA3-phosphatidylethanolamines are generated by human platelets and stimulate neutrophil integrin expression.

Redox Biol 2017 04 13;11:663-672. Epub 2017 Jan 13.

Systems Immunity Research Institute, and Institute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff CF14 4XN, UK. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2017.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288459PMC
April 2017

Tandem Mass Spectrometry in Combination with Product Ion Mobility for the Identification of Phospholipids.

Anal Chem 2017 01 13;89(1):916-921. Epub 2016 Dec 13.

Department of Pharmacology, University of Colorado Denver , Mail Stop 8303, 12801 E. 17th Avenue, Aurora, Colorado 80045, United States.

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http://pubs.acs.org/doi/10.1021/acs.analchem.6b04047
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http://dx.doi.org/10.1021/acs.analchem.6b04047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5250582PMC
January 2017

Increased ω6-Containing Phospholipids and Primary ω6 Oxidation Products in the Brain Tissue of Rats on an ω3-Deficient Diet.

PLoS One 2016 27;11(10):e0164326. Epub 2016 Oct 27.

Brain Physiology and Metabolism Section, National Institute on Aging, National Institutes of Health, Bethesda, MD, 20892, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0164326PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082804PMC
June 2017

Tandem mass spectrometry of novel ether-linked phospholipid analogs of anionic pulmonary surfactant phospholipids.

Rapid Commun Mass Spectrom 2016 Dec;30(24):2601-2606

Department of Pharmacology, University of Colorado Denver, Mail Stop 8303, 12081 E 17th Avenue, Aurora, CO, 80045, USA.

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http://doi.wiley.com/10.1002/rcm.7750
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http://dx.doi.org/10.1002/rcm.7750DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121057PMC
December 2016

Phospholipid Ozonation Products Activate the 5-Lipoxygenase Pathway in Macrophages.

Chem Res Toxicol 2016 08 3;29(8):1355-64. Epub 2016 Aug 3.

Department of Pharmacology, University of Colorado Denver , 12801 E. 17th Avenue, Mail Stop 8303, Aurora, Colorado 80045, United States.

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http://dx.doi.org/10.1021/acs.chemrestox.6b00193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029860PMC
August 2016

Membrane-dependent Activities of Human 15-LOX-2 and Its Murine Counterpart: IMPLICATIONS FOR MURINE MODELS OF ATHEROSCLEROSIS.

J Biol Chem 2016 09 19;291(37):19413-24. Epub 2016 Jul 19.

From the Department of Biological Sciences, Louisiana State University, Baton Rouge, Louisiana 70803 and

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http://www.jbc.org/lookup/doi/10.1074/jbc.M116.741454
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http://dx.doi.org/10.1074/jbc.M116.741454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016680PMC
September 2016

Mass Spectrometric Collisional Activation and Product Ion Mobility of Human Serum Neutral Lipid Extracts.

Anal Chem 2016 06 3;88(12):6274-82. Epub 2016 Jun 3.

Department of Pharmacology, University of Colorado Denver , Mail Stop 8303, 12801 East 17th Avenue, Aurora, Colorado 80045, United States.

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http://dx.doi.org/10.1021/acs.analchem.6b00292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007945PMC
June 2016

The discovery and early structural studies of arachidonic acid.

J Lipid Res 2016 07 3;57(7):1126-32. Epub 2016 May 3.

Department of Pharmacology, University of Colorado Denver, Aurora, CO 80045

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http://dx.doi.org/10.1194/jlr.R068072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918860PMC
July 2016

Mapping the Human Platelet Lipidome Reveals Cytosolic Phospholipase A2 as a Regulator of Mitochondrial Bioenergetics during Activation.

Cell Metab 2016 May 28;23(5):930-44. Epub 2016 Apr 28.

Institute of Infection and Immunity and Systems Immunity Research Institute, School of Medicine, Cardiff University, Cardiff CF14 4XN, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2016.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873619PMC
May 2016

Human Platelets Utilize Cycloxygenase-1 to Generate Dioxolane A3, a Neutrophil-activating Eicosanoid.

J Biol Chem 2016 Jun 22;291(26):13448-64. Epub 2016 Apr 22.

From the Systems Immunity Research Institute and Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom,

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http://dx.doi.org/10.1074/jbc.M115.700609DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919433PMC
June 2016

Structural analogs of pulmonary surfactant phosphatidylglycerol inhibit toll-like receptor 2 and 4 signaling.

J Lipid Res 2016 06 19;57(6):993-1005. Epub 2016 Apr 19.

Departments of Medicine, Basic Science Section, National Jewish Health, Denver, CO 80206

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http://dx.doi.org/10.1194/jlr.M065201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878184PMC
June 2016

Interactions of 2-O-arachidonylglycerol ether and ibuprofen with the allosteric and catalytic subunits of human COX-2.

J Lipid Res 2016 06 8;57(6):1043-50. Epub 2016 Apr 8.

Department of Biological Chemistry, University of Michigan, Ann Arbor, MI 48109

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http://dx.doi.org/10.1194/jlr.M067512DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878188PMC
June 2016

Prostaglandins from Cytosolic Phospholipase A2α/Cyclooxygenase-1 Pathway and Mitogen-activated Protein Kinases Regulate Gene Expression in Candida albicans-infected Macrophages.

J Biol Chem 2016 Mar 3;291(13):7070-86. Epub 2016 Feb 3.

From the Department of Pediatrics, National Jewish Health, Denver, Colorado 80206 and the Departments of Pharmacology and Pathology, University of Colorado Denver, Aurora, Colorado 80045

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http://dx.doi.org/10.1074/jbc.M116.714873DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807289PMC
March 2016

¹¹C-Choline PET/CT in Recurrent Prostate Cancer and Nonprostatic Neoplastic Processes.

Radiographics 2016 Jan-Feb;36(1):279-92

From the Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905-0002 (C.L.W., E.L.C., V.J.L., R.C.M., G.B.J., L.A.B.); and Eka Medical Center-Jakarta, BSD City, Tangerang, Indonesia (P.J.P.).

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http://dx.doi.org/10.1148/rg.2016150135DOI Listing
October 2016

Deletion of 5-Lipoxygenase in the Tumor Microenvironment Promotes Lung Cancer Progression and Metastasis through Regulating T Cell Recruitment.

J Immunol 2016 Jan 11;196(2):891-901. Epub 2015 Dec 11.

Department of Medicine, University of Colorado Denver, Aurora, CO 80045; Department of Pharmacology, University of Colorado Denver, Aurora, CO 80045

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http://dx.doi.org/10.4049/jimmunol.1501648DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705594PMC
January 2016

Specialized pro-resolving mediators: do they circulate in plasma?

Authors:
Robert C Murphy

J Lipid Res 2015 Sep 31;56(9):1641-2. Epub 2015 Jul 31.

Department of Pharmacology, University of Colorado Denver, Aurora, CO 80045

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http://dx.doi.org/10.1194/jlr.C062356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548769PMC
September 2015

Acyl-CoA synthetase 1 deficiency alters cardiolipin species and impairs mitochondrial function.

J Lipid Res 2015 Aug 1;56(8):1572-82. Epub 2015 Jul 1.

Department of Nutrition, University of North Carolina at Chapel Hill, NC 27599.

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http://dx.doi.org/10.1194/jlr.M059717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513998PMC
August 2015

Influenza induces IL-8 and GM-CSF secretion by human alveolar epithelial cells through HGF/c-Met and TGF-α/EGFR signaling.

Am J Physiol Lung Cell Mol Physiol 2015 Jun 10;308(11):L1178-88. Epub 2015 Apr 10.

Department of Medicine, National Jewish Health, Denver, Colorado; Department of Medicine, University of Colorado, Aurora, Colorado;

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http://dx.doi.org/10.1152/ajplung.00290.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451400PMC
June 2015

Botanical oils enriched in n-6 and n-3 FADS2 products are equally effective in preventing atherosclerosis and fatty liver.

J Lipid Res 2015 Jun 28;56(6):1191-205. Epub 2015 Apr 28.

Departments of Internal Medicine-Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, NC 27157 Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC 27157.

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http://dx.doi.org/10.1194/jlr.M059170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442876PMC
June 2015

Ion Mobility and Tandem Mass Spectrometry of Phosphatidylglycerol and Bis(monoacylglycerol)phosphate (BMP).

Int J Mass Spectrom 2015 Feb;378:255-263

Department of Pharmacology, University of Colorado Denver, Mail Stop 8303, 12801 E. 17 Avenue, Aurora, CO 80045, USA.

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http://dx.doi.org/10.1016/j.ijms.2014.08.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394388PMC
February 2015

Evidence for an N-methyl transfer reaction in phosphatidylcholines with a terminal aldehyde during negative electrospray ionization tandem mass spectrometry.

Anal Bioanal Chem 2015 Jul 4;407(17):5045-52. Epub 2015 Mar 4.

Department of Pharmacology, University of Colorado Denver, 12801 E. 17th Ave, Aurora, CO, 80045, USA.

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http://dx.doi.org/10.1007/s00216-015-8555-zDOI Listing
July 2015

Measurement of estradiol, estrone, and testosterone in postmenopausal human serum by isotope dilution liquid chromatography tandem mass spectrometry without derivatization.

Steroids 2015 Apr 21;96:89-94. Epub 2015 Jan 21.

Department of Obstetrics and Gynecology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO, United States. Electronic address:

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http://dx.doi.org/10.1016/j.steroids.2015.01.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366052PMC
April 2015

Identification of oxidized phospholipids in bronchoalveolar lavage exposed to low ozone levels using multivariate analysis.

Anal Biochem 2015 Apr 7;474:50-8. Epub 2015 Jan 7.

Department of Pharmacology, University of Colorado Denver, Aurora, CO 80045, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ab.2014.12.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375957PMC
April 2015

Phosphatidylinositol inhibits respiratory syncytial virus infection.

J Lipid Res 2015 Mar 5;56(3):578-87. Epub 2015 Jan 5.

Department of Medicine, Program in Cell Biology, National Jewish Health, Denver, CO 80206.

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http://dx.doi.org/10.1194/jlr.M055723DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340305PMC
March 2015

Proinflammatory responses induced by CD40 in retinal endothelial and Müller cells are inhibited by blocking CD40-Traf2,3 or CD40-Traf6 signaling.

Invest Ophthalmol Vis Sci 2014 Dec 4;55(12):8590-7. Epub 2014 Dec 4.

Division of Infectious Diseases and HIV Medicine, Department of Medicine, Case Western Reserve University, Cleveland, Ohio, United States Department of Ophthalmology and Visual Sciences, Case Western Reserve University, Cleveland, Ohio, United States Department of Pathology, Case Western Reserve University, Cleveland, Ohio, United States.

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http://iovs.arvojournals.org/Article.aspx?doi=10.1167/iovs.1
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http://dx.doi.org/10.1167/iovs.14-15340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280881PMC
December 2014

The role of PGE2 in intestinal inflammation and tumorigenesis.

Prostaglandins Other Lipid Mediat 2015 Jan-Mar;116-117:26-36. Epub 2014 Oct 22.

Center for Molecular Medicine and Colon Cancer Prevention, University of Connecticut Health Center, Farmington, CT 06030, United States. Electronic address:

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http://dx.doi.org/10.1016/j.prostaglandins.2014.10.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385488PMC
December 2015

Schwann cell-derived Apolipoprotein D controls the dynamics of post-injury myelin recognition and degradation.

Front Cell Neurosci 2014 11;8:374. Epub 2014 Nov 11.

Lazarillo Lab, Departamento de Bioquímica y Biología Molecular y Fisiología, Instituto de Biología y Genética Molecular, Universidad de Valladolid-CSIC Valladolid, Spain.

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http://dx.doi.org/10.3389/fncel.2014.00374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227524PMC
November 2014

Malignant involvement of the peripheral nervous system in patients with cancer: multimodality imaging and pathologic correlation.

Radiographics 2014 Nov-Dec;34(7):1987-2007

From the Departments of Radiology (A.B.C., B.M.H., R.J.S., K.K.A., C.H.H., G.B.J., R.C.M., R.F.M., P.J.P.) and Immunology (G.B.J.), Mayo Clinic, Mayo Building E2, 200 First St SW, Rochester, MN 55905.

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http://dx.doi.org/10.1148/rg.347130129DOI Listing
November 2015

Chemotherapeutic agents subvert tumor immunity by generating agonists of platelet-activating factor.

Cancer Res 2014 Dec 10;74(23):7069-78. Epub 2014 Oct 10.

Department of Dermatology, Indiana University School of Medicine, Indianapolis, Indiana. Department of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, Indiana. The Richard L. Roudebush V.A. Medical Center, Indianapolis, Indiana.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-2043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252249PMC
December 2014

Structural characterization of the pulmonary innate immune protein SPLUNC1 and identification of lipid ligands.

FASEB J 2014 Dec 15;28(12):5349-60. Epub 2014 Sep 15.

Integrated Department of Immunology, National Jewish Health and University of Colorado Denver, Denver, Colorado, USA;

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http://dx.doi.org/10.1096/fj.14-259291DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232288PMC
December 2014

Transcellular biosynthesis of eicosanoid lipid mediators.

Biochim Biophys Acta 2015 Apr 16;1851(4):377-82. Epub 2014 Sep 16.

Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Milan, Italy; IBIM, CNR, Palermo, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bbalip.2014.09.002DOI Listing
April 2015

Lysophospholipid acyltransferases and eicosanoid biosynthesis in zebrafish myeloid cells.

Prostaglandins Other Lipid Mediat 2014 Oct 28;113-115:52-61. Epub 2014 Aug 28.

Department of Pharmacology, University of Colorado Denver, Aurora, CO 80045, United States. Electronic address:

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http://dx.doi.org/10.1016/j.prostaglandins.2014.08.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252513PMC
October 2014

Biomarkers for personalizing omega-3 fatty acid dosing.

Cancer Prev Res (Phila) 2014 Oct 19;7(10):1011-22. Epub 2014 Aug 19.

Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan. Department of Pharmacology, University of Michigan Medical School, Ann Arbor, Michigan. VA Medical Center, Ann Arbor, Michigan.

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http://dx.doi.org/10.1158/1940-6207.CAPR-14-0134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4185239PMC
October 2014

Topical photodynamic therapy induces systemic immunosuppression via generation of platelet-activating factor receptor ligands.

J Invest Dermatol 2015 Jan 22;135(1):321-323. Epub 2014 Jul 22.

Department of Dermatology, Indiana University School of Medicine, Indianapolis, Indiana, USA; Department of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, Indiana, USA; The Richard L. Roudebush V.A. Medical Center, Indianapolis, Indiana, USA. Electronic address:

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http://dx.doi.org/10.1038/jid.2014.313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268233PMC
January 2015

Relationship between a common variant in the fatty acid desaturase (FADS) cluster and eicosanoid generation in humans.

J Biol Chem 2014 Aug 24;289(32):22482-9. Epub 2014 Jun 24.

the Department of Physiology/Pharmacology, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, the Center for Botanical Lipids and Inflammatory Disease Prevention, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, the Molecular Medicine and Translation Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157

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http://dx.doi.org/10.1074/jbc.M114.579557DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139254PMC
August 2014

Diet-gene interactions and PUFA metabolism: a potential contributor to health disparities and human diseases.

Nutrients 2014 May 21;6(5):1993-2022. Epub 2014 May 21.

Division of Allergy and Clinical Immunology, Department of Medicine, The Johns Hopkins University, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.3390/nu6051993DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042578PMC
May 2014

Blocking leukotriene synthesis attenuates the pathophysiology of traumatic brain injury and associated cognitive deficits.

Exp Neurol 2014 Jun 25;256:7-16. Epub 2014 Mar 25.

Neuroscience Program, University of Colorado, Anschutz Medical Campus, Aurora, CO 80045, USA; Department of Pharmacology, University of Colorado, Anschutz Medical Campus, Aurora, CO 80045, USA. Electronic address:

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http://dx.doi.org/10.1016/j.expneurol.2014.03.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731038PMC
June 2014

Platelet lipidomics: modern day perspective on lipid discovery and characterization in platelets.

Circ Res 2014 Mar;114(7):1185-203

From the Institute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, United Kingdom (V.B.O'D.); Department of Pharmacology, University of Colorado at Denver, Aurora (R.C.M.); and Birmingham Platelet Group, Centre for Cardiovascular Sciences, Institute of Biomedical Research, College of Medical and Dental Sciences, Birmingham, United Kingdom (S.P.W.).

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http://dx.doi.org/10.1161/CIRCRESAHA.114.301597DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021279PMC
March 2014

Measurement of lysophospholipid acyltransferase activities using substrate competition.

J Lipid Res 2014 Apr 21;55(4):782-91. Epub 2014 Feb 21.

Department of Pharmacology, University of Colorado Denver, Aurora, CO 80045.

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http://dx.doi.org/10.1194/jlr.D044636DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966712PMC
April 2014

Inhibition of macrophage fatty acid β-oxidation exacerbates palmitate-induced inflammatory and endoplasmic reticulum stress responses.

Diabetologia 2014 May 1;57(5):1067-77. Epub 2014 Feb 1.

Faculty of Medicine, Institute of Biochemistry I/ZAFES, Goethe University Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany.

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http://dx.doi.org/10.1007/s00125-014-3173-4DOI Listing
May 2014

A phosphatidylinositol transfer protein integrates phosphoinositide signaling with lipid droplet metabolism to regulate a developmental program of nutrient stress-induced membrane biogenesis.

Mol Biol Cell 2014 Mar 8;25(5):712-27. Epub 2014 Jan 8.

Lineberger Comprehensive Cancer Center, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7090 Department of Molecular and Cellular Medicine, Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843-1114 Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY 11794-5215 Department of Biochemistry, Emory University School of Medicine, Atlanta, GA 30322-4250 R. L. Juliano Structural Bioinformatics Core, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7260 Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-3280 Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT 84112-5650 Department of Pharmacology, University of Colorado Health Sciences Center, Denver, CO 80045-0511 Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN 37232-6600.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937096PMC
March 2014

Spatial organization of lipids in the human retina and optic nerve by MALDI imaging mass spectrometry.

J Lipid Res 2014 Mar 23;55(3):504-15. Epub 2013 Dec 23.

Department of Pharmacology, University of Colorado Denver, Aurora, CO 80045; and.

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http://dx.doi.org/10.1194/jlr.M044990DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934734PMC
March 2014

Update on positron emission tomography for imaging of prostate cancer.

Int J Urol 2014 Jan 1;21(1):12-23. Epub 2013 Sep 1.

Department of Radiology, Kobe University School of Medicine, Kobe, Japan.

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http://dx.doi.org/10.1111/iju.12250DOI Listing
January 2014

Mechanism of formation of the major estradiol product ions following collisional activation of the molecular anion in a tandem quadrupole mass spectrometer.

J Am Soc Mass Spectrom 2013 Oct 18;24(10):1451-5. Epub 2013 Aug 18.

Department of Obstetrics and Gynecology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO, 80045, USA.

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http://dx.doi.org/10.1007/s13361-013-0705-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786604PMC
October 2013

99mTc-MDP SPECT/CT of the spine and sacrum at a multispecialty institution: clinical use, findings, and impact on patient management.

Nucl Med Commun 2013 Nov;34(11):1097-106

Department of Radiology, Mayo Clinic College of Graduate Medical Education, Rochester, Minnesota, USA.

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November 2013

Major urinary metabolites of 6-keto-prostaglandin F2α in mice.

J Lipid Res 2013 Jul 3;54(7):1906-14. Epub 2013 May 3.

Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1194/jlr.M037192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679392PMC
July 2013

Choline PET/CT for imaging prostate cancer: an update.

Ann Nucl Med 2013 Aug 30;27(7):581-91. Epub 2013 Apr 30.

Department of Radiology, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan.

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http://dx.doi.org/10.1007/s12149-013-0731-7DOI Listing
August 2013

In memoriam: Charles (Chuck) Crawford Sweeley, Jr. (1930-2012).

J Lipid Res 2013 Jan;54(1):1-4

School of Biology and Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, GA 30332-0230, USA.

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http://dx.doi.org/10.1194/jlr.e033993DOI Listing
January 2013

New families of bioactive oxidized phospholipids generated by immune cells: identification and signaling actions.

Blood 2012 Sep 16;120(10):1985-92. Epub 2012 Jul 16.

Institute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, United Kingdom.

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http://dx.doi.org/10.1182/blood-2012-04-402826DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437593PMC
September 2012

Mammalian fatty acid synthase activity from crude tissue lysates tracing ¹³C-labeled substrates using gas chromatography-mass spectrometry.

Anal Biochem 2012 Sep 20;428(2):158-66. Epub 2012 Jun 20.

Department of Pathology, University of Colorado, Anschutz Medical Campus, Aurora, CO 80045, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415257PMC
September 2012

Cholesteryl ester acyl oxidation and remodeling in murine macrophages: formation of oxidized phosphatidylcholine.

J Lipid Res 2012 Aug 4;53(8):1588-97. Epub 2012 Jun 4.

Department of Pharmacology, University of Colorado Denver, Aurora, CO 80045, USA.

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http://dx.doi.org/10.1194/jlr.M026799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540862PMC
August 2012

Platelet-activating factor receptor agonists mediate xeroderma pigmentosum A photosensitivity.

J Biol Chem 2012 Mar 1;287(12):9311-21. Epub 2012 Feb 1.

Department of Dermatology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA.

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http://dx.doi.org/10.1074/jbc.M111.332395DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308814PMC
March 2012

Group IVA phospholipase A₂ is necessary for growth cone repulsion and collapse.

J Neurochem 2012 Mar 6;120(6):974-84. Epub 2012 Feb 6.

Department of Pediatrics, Neuroscience Program, and Colorado Intellectual and Developmental Disabilities Research Center, University of Colorado School of Medicine, Aurora, Colorado, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2012.07651.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296835PMC
March 2012

The cysteinyl leukotriene 2 receptor mediates retinal edema and pathological neovascularization in a murine model of oxygen-induced retinopathy.

FASEB J 2012 Mar 30;26(3):1100-9. Epub 2011 Nov 30.

Department of Biomedical and Molecular Sciences, Queen's University, 18 Stuart St., 433 Botterell Hall, Kingston, ON, Canada K7L 3N6.

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March 2012

Lipidomics and imaging mass spectrometry.

Biochim Biophys Acta 2011 Nov 17;1811(11):635-6. Epub 2011 Sep 17.

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November 2011