Robert Brychta

Robert Brychta

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Robert Brychta

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Associations of sleep patterns with metabolic syndrome indices, body composition, and energy intake in children and adolescents.

Pediatr Obes 2019 06 31;14(6):e12507. Epub 2019 Jan 31.

Section on Growth and Obesity, Program in Endocrinology, Metabolism and Genetics, Division of Intramural Research Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), Department of Health and Human Services (DHHS), Bethesda, MD, USA.

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http://dx.doi.org/10.1111/ijpo.12507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504608PMC
June 2019

Vagal and Sympathetic Function in Neuropathic Postural Tachycardia Syndrome.

Hypertension 2019 May;73(5):1087-1096

Division of Clinical Pharmacology, Department of Medicine, Autonomic Dysfunction Center (K.S., S.R.R., D.R., I.B., A.D.), Vanderbilt University School of Medicine, Nashville, TN.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.118.11803DOI Listing
May 2019

Quantification of the capacity for cold-induced thermogenesis in young men with and without obesity.

J Clin Endocrinol Metab 2019 May 31. Epub 2019 May 31.

Diabetes, Endocrinology, and Obesity Branch (DEOB), National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1210/jc.2019-00728DOI Listing
May 2019

Whole Body and Regional Quantification of Active Human Brown Adipose Tissue Using 18F-FDG PET/CT.

J Vis Exp 2019 Apr 1(146). Epub 2019 Apr 1.

Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health;

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https://www.jove.com/video/58469/whole-body-regional-quantif
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http://dx.doi.org/10.3791/58469DOI Listing
April 2019

Dynamic sitting: Measurement and associations with metabolic health.

J Sports Sci 2019 Mar 30:1-9. Epub 2019 Mar 30.

a Department of Social Medicine/CAPHRI Care and Public Health Research Institute , Maastricht University , Maastricht , The Netherlands.

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http://dx.doi.org/10.1080/02640414.2019.1592800DOI Listing
March 2019

Effects of Interrupting Sedentary Behavior With Short Bouts of Moderate Physical Activity on Glucose Tolerance in Children With Overweight and Obesity: A Randomized Crossover Trial.

Diabetes Care 2018 10 6;41(10):2220-2228. Epub 2018 Aug 6.

Section on Growth and Obesity, Program in Endocrinology, Metabolism and Genetics, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD

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http://dx.doi.org/10.2337/dc18-0774DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150427PMC
October 2018

Comparing ActiGraph equations for estimating energy expenditure in older adults.

J Sports Sci 2018 Jun 18:1-8. Epub 2018 Jun 18.

d The School of Human Movement and Nutrition Sciences , The University of Queensland , Brisbane , Australia.

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http://dx.doi.org/10.1080/02640414.2018.1488437DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298850PMC
June 2018

Increased Physical Activity Associated with Less Weight Regain Six Years After "The Biggest Loser" Competition.

Obesity (Silver Spring) 2017 11;25(11):1838-1843

National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1002/oby.21986DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757520PMC
November 2017

Mapping of human brown adipose tissue in lean and obese young men.

Proc Natl Acad Sci U S A 2017 08 24;114(32):8649-8654. Epub 2017 Jul 24.

Diabetes, Endocrinology, and Obesity Branch, Intramural Research Program, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892;

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http://www.pnas.org/lookup/doi/10.1073/pnas.1705287114
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http://dx.doi.org/10.1073/pnas.1705287114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559032PMC
August 2017

Sleep deficiency on school days in Icelandic youth, as assessed by wrist accelerometry.

Sleep Med 2017 05 10;33:103-108. Epub 2017 Feb 10.

Center of Sport and Health Sciences, University of Iceland, Reykjavik, Iceland; Department of Sport and Physical Activity, Bergen University College, Bergen, Norway. Electronic address:

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http://dx.doi.org/10.1016/j.sleep.2016.12.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314493PMC
May 2017

Accelerometer-measured dose-response for physical activity, sedentary time, and mortality in US adults.

Am J Clin Nutr 2016 11 5;104(5):1424-1432. Epub 2016 Oct 5.

Behavioral Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD.

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http://dx.doi.org/10.3945/ajcn.116.135129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081718PMC
November 2016

Response to "Overstated metabolic adaptation after 'The Biggest Loser' intervention".

Obesity (Silver Spring) 2016 10 1;24(10):2026. Epub 2016 Sep 1.

Department of Kinesiology, Towson University, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1002/oby.21635DOI Listing
October 2016

Persistent metabolic adaptation 6 years after "The Biggest Loser" competition.

Obesity (Silver Spring) 2016 08 2;24(8):1612-9. Epub 2016 May 2.

National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health (NIH), Bethesda, Maryland, USA.

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http://dx.doi.org/10.1002/oby.21538DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989512PMC
August 2016

Bombesin-like receptor 3 regulates blood pressure and heart rate via a central sympathetic mechanism.

Am J Physiol Heart Circ Physiol 2016 Apr 22;310(7):H891-8. Epub 2016 Jan 22.

Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland;

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http://dx.doi.org/10.1152/ajpheart.00963.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865066PMC
April 2016

Effects of Interrupting Children's Sedentary Behaviors With Activity on Metabolic Function: A Randomized Trial.

J Clin Endocrinol Metab 2015 Oct 27;100(10):3735-43. Epub 2015 Aug 27.

Division of Cancer Control and Population Sciences (B.R.B., D.B.), and Pediatric Oncology Branch (P.L.W.), National Cancer Institute, Bethesda, Maryland 20892-9762; Section on Growth and Obesity, Program in Developmental Endocrinology and Genetics (B.R.B., A.P., S.M.B., I.L.T., J.A.Y.), Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland 20892-1103; Nutrition (S.B.B., A.B.C.), Rehabilitation Medicine (B.E.D.), and Nursing (K.P.S.) Departments, Hatfield Clinical Research Center, National Institutes of Health, Bethesda, Maryland 20892; Diabetes, Endocrinology, and Obesity Branch (R.J.B., J.D.H., K.Y.C.), National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892-2560; and Cardiovascular and Pulmonary Branch (D.R.R.), National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892.

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http://dx.doi.org/10.1210/jc.2015-2803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596047PMC
October 2015

Does Visceral Fat Estimated by Dual-Energy X-ray Absorptiometry Independently Predict Cardiometabolic Risks in Adults?

J Diabetes Sci Technol 2015 Jul 23;9(4):917-24. Epub 2015 Mar 23.

Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA

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http://dx.doi.org/10.1177/1932296815577424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525640PMC
July 2015

Ability of thigh-worn ActiGraph and activPAL monitors to classify posture and motion.

Med Sci Sports Exerc 2015 May;47(5):952-9

1Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, Rockville, MD; 2Risk Factor Monitoring and Methods Branch, Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville, MD; 3Biometry Research Group, Division of Cancer Prevention, National Cancer Institute, Rockville, MD; and 4Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD.

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http://dx.doi.org/10.1249/MSS.0000000000000497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330899PMC
May 2015

RM-493, a melanocortin-4 receptor (MC4R) agonist, increases resting energy expenditure in obese individuals.

J Clin Endocrinol Metab 2015 Apr 12;100(4):1639-45. Epub 2015 Feb 12.

Diabetes, Endocrinology, and Obesity Branch (K.Y.C., R.M., B.S.A., K.P.M., P.S., R.J.B., X.Z., M.R., T.L.P., M.L.R., M.C.S.), National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892; Department of Molecular Physiology and Biophysics (R.D.C., B.L.P.), Vanderbilt University School of Medicine, Nashville, Tennessee 37232; and Rhythm Pharmaceuticals (K.M.G., L.H.T.V.d.P.), Boston, Massachusetts 02116.

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http://rhythmpharmaceutical.com/pdfs/Chen%202015%20JCEM.pdf
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http://press.endocrine.org/doi/10.1210/jc.2014-4024
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http://dx.doi.org/10.1210/jc.2014-4024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399297PMC
April 2015

Temperature-acclimated brown adipose tissue modulates insulin sensitivity in humans.

Diabetes 2014 Nov 22;63(11):3686-98. Epub 2014 Jun 22.

Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD Division of Endocrinology and Metabolism, Virginia Commonwealth University, Richmond, VA

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http://dx.doi.org/10.2337/db14-0513DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207391PMC
November 2014

Midlife determinants associated with sedentary behavior in old age.

Med Sci Sports Exerc 2014 Jul;46(7):1359-65

1Department of Social Medicine/CAPHRI School for Public Health and Primary Care, Maastricht University, Maastricht, THE NETHERLANDS; 2Institute of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense, DENMARK; 3Icelandic Heart Association, Kopavogur, ICELAND; 4Research Center of Movement Science, University of Iceland, Reykjavik, ICELAND; 5Laboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute on Aging, Bethesda, MD; 6Diabetes Endocrinology and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD; 7Center for Sport and Health Sciences, Iceland University of Education, Laugarvatn, ICELAND; 8University of Iceland, Reykjavik, ICELAND; 9Faculty of Medicine, University of Iceland, Reykjavik, ICELAND; 10Department of Geriatrics, Landspitali National University Hospital, Reykjavik, ICELAND; and 11Department of Internal Medicine/Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Centre, Maastricht, THE NETHERLANDS.

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http://dx.doi.org/10.1249/MSS.0000000000000246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061270PMC
July 2014

Evolution of accelerometer methods for physical activity research.

Br J Sports Med 2014 Jul 29;48(13):1019-23. Epub 2014 Apr 29.

Diabetes, Endocrinology, and Obesity Branch, Intramural Research Program, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1136/bjsports-2014-093546DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141534PMC
July 2014

Changes in daily activity patterns with age in U.S. men and women: National Health and Nutrition Examination Survey 2003-04 and 2005-06.

J Am Geriatr Soc 2014 Jul 24;62(7):1263-71. Epub 2014 Jun 24.

Laboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute on Aging, Bethesda, Maryland; Epidemiology Group, School of Medicine and Dentistry, University of Aberdeen, Aberdeen, UK.

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http://dx.doi.org/10.1111/jgs.12893DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115191PMC
July 2014

Self-reported adherence to the physical activity recommendation and determinants of misperception in older adults.

J Aging Phys Act 2014 Apr 22;22(2):226-34. Epub 2013 May 22.

VU University Amsterdam and VU University Medical Center, Amsterdam, The Netherlands.

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http://journals.humankinetics.com/doi/10.1123/japa.2012-0219
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http://dx.doi.org/10.1123/japa.2012-0219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929529PMC
April 2014

Irisin and FGF21 are cold-induced endocrine activators of brown fat function in humans.

Cell Metab 2014 Feb;19(2):302-9

Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2013.12.017DOI Listing
February 2014

Reduced insulin sensitivity in adults with pseudohypoparathyroidism type 1a.

J Clin Endocrinol Metab 2013 Nov 12;98(11):E1796-801. Epub 2013 Sep 12.

MD, Chief, Clinical Endocrine Section, Diabetes, Endocrinology, and Obesity Branch, National Institutes of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 10 Center Drive MSC 1613, Building 10, CRC, Room 6-3940, Bethesda, Maryland 20892-1613.

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http://dx.doi.org/10.1210/jc.2013-1594DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816268PMC
November 2013

Brown fat activation mediates cold-induced thermogenesis in adult humans in response to a mild decrease in ambient temperature.

J Clin Endocrinol Metab 2013 Jul 18;98(7):E1218-23. Epub 2013 Jun 18.

Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, Clinical Center, National Institutes of Health, Bethesda, Maryland 20892-1613, USA.

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http://dx.doi.org/10.1210/jc.2012-4213DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701264PMC
July 2013

Mild cold exposure modulates fibroblast growth factor 21 (FGF21) diurnal rhythm in humans: relationship between FGF21 levels, lipolysis, and cold-induced thermogenesis.

J Clin Endocrinol Metab 2013 Jan 12;98(1):E98-102. Epub 2012 Nov 12.

Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Building 10, Clinical Research Center, 10 Center Drive, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1210/jc.2012-3107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537100PMC
January 2013

Association of sedentary time with mortality independent of moderate to vigorous physical activity.

PLoS One 2012 13;7(6):e37696. Epub 2012 Jun 13.

National Institute on Aging, Intramural Research Program, Laboratory of Epidemiology, Demography, and Biometry, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0037696PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374810PMC
December 2012

Redefining the roles of sensors in objective physical activity monitoring.

Med Sci Sports Exerc 2012 Jan;44(1 Suppl 1):S13-23

Diabetes, Endocrinology, and Obesity Branch, Intramural Research Program, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1249/MSS.0b013e3182399bc8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245644PMC
January 2012

Employment and physical activity in the U.S.

Am J Prev Med 2011 Aug;41(2):136-45

Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1016/j.amepre.2011.03.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221416PMC
August 2011

Sedentary activity associated with metabolic syndrome independent of physical activity.

Diabetes Care 2011 Feb;34(2):497-503

Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, Maryland, USA.

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http://dx.doi.org/10.2337/dc10-0987DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024375PMC
February 2011

Minimal changes in environmental temperature result in a significant increase in energy expenditure and changes in the hormonal homeostasis in healthy adults.

Eur J Endocrinol 2010 Dec 8;163(6):863-72. Epub 2010 Sep 8.

Clinical Endocrinology Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892-1613, USA.

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http://dx.doi.org/10.1530/EJE-10-0627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113548PMC
December 2010

Validation of the ActiGraph two-regression model for predicting energy expenditure.

Med Sci Sports Exerc 2010 Sep;42(9):1785-92

National Institute of Diabetes and Digestive and Kidney Diseases/Clinical Endocrinology Branch, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1249/MSS.0b013e3181d5a984DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919650PMC
September 2010

Energy expenditure: measurement of human metabolism.

IEEE Eng Med Biol Mag 2010 Jan-Feb;29(1):42-7

NIH Clinical Center, 10 Center Drive, Bldg 10, Room 6-3940, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1109/MEMB.2009.935463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440543PMC
June 2010

Optimizing energy expenditure detection in human metabolic chambers.

Conf Proc IEEE Eng Med Biol Soc 2009 ;2009:6864-8

Clinical Endocrinology Branch of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health, Bethesda, MD 20892, USA. brychtar@ niddk.nih.gov

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http://dx.doi.org/10.1109/IEMBS.2009.5333121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467262PMC
March 2010

Lateralization of expression of neural sympathetic activity to the vessels and effects of carotid baroreceptor stimulation.

Am J Physiol Heart Circ Physiol 2009 Jun 10;296(6):H1758-65. Epub 2009 Apr 10.

Division of Clinical Pharmacology, Department of Medicine, Autonomic Dysfunction Center, Vanderbilt University, Nashville, Tennessee, USA.

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http://dx.doi.org/10.1152/ajpheart.01045.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716107PMC
June 2009

Body composition measured by dual-energy X-ray absorptiometry half-body scans in obese adults.

Obesity (Silver Spring) 2009 Jun 19;17(6):1281-6. Epub 2009 Feb 19.

Clinical Endocrinology Branch, The National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1038/oby.2009.14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709755PMC
June 2009

Yohimbine attenuates baroreflex-mediated bradycardia in humans.

Hypertension 2007 Nov 17;50(5):899-903. Epub 2007 Sep 17.

Franz Volhard Clinical Research Center, Medical Faculty of the Charité and HELIOS Klinikum, Berlin, Germany.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.107.095984DOI Listing
November 2007

Sympathetic nerve traffic and circulating norepinephrine levels in RGS2-deficient mice.

Auton Neurosci 2007 Oct 15;136(1-2):52-7. Epub 2007 May 15.

Medical Faculty of the Charité, Franz Volhard Clinic, HELIOS Klinikum-Berlin, Wiltbergstrasse 50, 13125 Berlin, Germany.

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http://dx.doi.org/10.1016/j.autneu.2007.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480399PMC
October 2007

Physical activity monitors: do more sensors mean better precision?

J Diabetes Sci Technol 2007 Sep;1(5):768-70

Clinical Endocrinology Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2769662PMC
http://dx.doi.org/10.1177/193229680700100523DOI Listing
September 2007

Spike detection in human muscle sympathetic nerve activity using the kurtosis of stationary wavelet transform coefficients.

J Neurosci Methods 2007 Mar 2;160(2):359-67. Epub 2006 Nov 2.

Vanderbilt University School of Medicine, Division of Clinical Pharmacology, Department of Medicine, Autonomic Dysfunction Center, Nashville, TN 37232, USA.

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http://dx.doi.org/10.1016/j.jneumeth.2006.09.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2075105PMC
March 2007

A simplified two-component model of blood pressure fluctuation.

Am J Physiol Heart Circ Physiol 2007 Feb 29;292(2):H1193-203. Epub 2006 Sep 29.

Autonomic Dysfunction Center, Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-2195, USA.

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http://www.physiology.org/doi/10.1152/ajpheart.00645.2006
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http://dx.doi.org/10.1152/ajpheart.00645.2006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1987355PMC
February 2007

Wavelet methods for spike detection in mouse renal sympathetic nerve activity.

IEEE Trans Biomed Eng 2007 Jan;54(1):82-93

Biomedical Engineering Department of Vanderbilt University, Nashville, TN 37235, USA.

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http://dx.doi.org/10.1109/TBME.2006.883830DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2075098PMC
January 2007