Robert Brink

Robert Brink

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Germinal centres and autoantibodies.

Immunol Cell Biol 2020 Feb 20. Epub 2020 Feb 20.

Immunology Division, Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia.

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http://dx.doi.org/10.1111/imcb.12321DOI Listing
February 2020

Selection in the germinal center.

Curr Opin Immunol 2019 Dec 10;63:29-34. Epub 2019 Dec 10.

Immunology Division, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, NSW 2010, Australia; St Vincent's Clinical School, UNSW Australia, 390 Victoria St, Darlinghurst, NSW 2010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2019.11.001DOI Listing
December 2019

Activating mutations in PIK3CD disrupt the differentiation and function of human and murine CD4 T cells.

J Allergy Clin Immunol 2019 Jul 6;144(1):236-253. Epub 2019 Feb 6.

Immunology Division, Garvan Institute of Medical Research, Darlinghurst, Australia; St Vincent's Clinical School, University of New South Wales, Sydney, Australia; Clinical Immunogenomics Research Consortia Australia, Sydney, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2019.01.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612302PMC
July 2019

B cell-intrinsic requirement for STK4 in humoral immunity in mice and human subjects.

J Allergy Clin Immunol 2019 Jun 20;143(6):2302-2305. Epub 2019 Feb 20.

Immunology Division, Garvan Institute of Medical Research, Sydney, Australia; St Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Sydney, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2019.02.010DOI Listing
June 2019

Knockout of glucose transporter GLUT6 has minimal effects on whole body metabolic physiology in mice.

Am J Physiol Endocrinol Metab 2018 08 17;315(2):E286-E293. Epub 2018 Apr 17.

School of Biotechnology and Biomolecular Sciences, University of New South Wales , Sydney, New South Wales , Australia.

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http://dx.doi.org/10.1152/ajpendo.00082.2018DOI Listing
August 2018

Self-Reactive B Cells in the Germinal Center Reaction.

Annu Rev Immunol 2018 04 22;36:339-357. Epub 2018 Jan 22.

Immunology Division, Garvan Institute of Medical Research, Darlinghurst, New South Wales 2010, Australia; email: ,

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http://dx.doi.org/10.1146/annurev-immunol-051116-052510DOI Listing
April 2018

GPR65 inhibits experimental autoimmune encephalomyelitis through CD4 T cell independent mechanisms that include effects on iNKT cells.

Immunol Cell Biol 2018 02 19;96(2):128-136. Epub 2017 Dec 19.

Immunology Division, Garvan Institute of Medical Research, Sydney, NSW, Australia.

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http://dx.doi.org/10.1111/imcb.1031DOI Listing
February 2018

CCR6 Defines Memory B Cell Precursors in Mouse and Human Germinal Centers, Revealing Light-Zone Location and Predominant Low Antigen Affinity.

Immunity 2017 12;47(6):1142-1153.e4

Immunology Division, Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia; St. Vincent's Clinical School, UNSW Sydney, Darlinghurst, NSW 2010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2017.11.022DOI Listing
December 2017

Structural basis of antigen recognition: crystal structure of duck egg lysozyme.

Acta Crystallogr D Struct Biol 2017 Nov 25;73(Pt 11):910-920. Epub 2017 Oct 25.

Immunology Division, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, NSW 2010, Australia.

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http://dx.doi.org/10.1107/S2059798317013730DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683014PMC
November 2017

Murine LRBA deficiency causes CTLA-4 deficiency in Tregs without progression to immune dysregulation.

Immunol Cell Biol 2017 10 14;95(9):775-788. Epub 2017 Jun 14.

Immunology Division, Garvan Institute for Medical Research, Sydney, NSW, Australia.

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http://dx.doi.org/10.1038/icb.2017.50DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636941PMC
October 2017

IL-2 Shapes the Survival and Plasticity of IL-17-Producing γδ T Cells.

J Immunol 2017 10 23;199(7):2366-2376. Epub 2017 Aug 23.

Immunology Division, Garvan Institute of Medical Research, Darlinghurst, New South Wales 2010, Australia; and

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http://dx.doi.org/10.4049/jimmunol.1700335DOI Listing
October 2017

In vivo photolabeling of tumor-infiltrating cells reveals highly regulated egress of T-cell subsets from tumors.

Proc Natl Acad Sci U S A 2017 05 15;114(22):5677-5682. Epub 2017 May 15.

Immunology Division, Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia;

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http://dx.doi.org/10.1073/pnas.1618446114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465915PMC
May 2017

Targeted deletion of Traf2 allows immunosuppression-free islet allograft survival in mice.

Diabetologia 2017 04 6;60(4):679-689. Epub 2017 Jan 6.

Transplantation Immunology Group, Immunology Division, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, NSW, 2010, Australia.

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http://dx.doi.org/10.1007/s00125-016-4198-7DOI Listing
April 2017

Plasma cell and memory B cell differentiation from the germinal center.

Curr Opin Immunol 2017 Apr 17;45:97-102. Epub 2017 Mar 17.

Immunology Division, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, NSW 2010, Australia; St Vincent's Clinical School, UNSW Australia, 390 Victoria St, Darlinghurst, NSW 2010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2017.03.006DOI Listing
April 2017

B-cell-specific STAT3 deficiency: Insight into the molecular basis of autosomal-dominant hyper-IgE syndrome.

J Allergy Clin Immunol 2016 11 11;138(5):1455-1458.e3. Epub 2016 Jun 11.

Immunology Division, Garvan Institute of Medical Research, Darlinghurst, Australia; St Vincent's Clinical School, UNSW Australia, Darlinghurst, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.05.018DOI Listing
November 2016

Antigen-affinity controls pre-germinal center B cell selection by promoting Mcl-1 induction through BAFF receptor signaling.

Sci Rep 2016 10 20;6:35673. Epub 2016 Oct 20.

Department of Experimental Immunology, Academic Medical Center, 1105AZ, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/srep35673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071843PMC
October 2016

EBI2 unlocks the door to the Tfh cell nursery.

Authors:
Robert Brink

Immunol Cell Biol 2016 08 14;94(7):621-2. Epub 2016 Jun 14.

Immunology Division, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia.

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http://dx.doi.org/10.1038/icb.2016.52DOI Listing
August 2016

Collaboration between tumor-specific CD4+ T cells and B cells in anti-cancer immunity.

Oncotarget 2016 May;7(21):30211-29

T Cell Biology Laboratory, Centenary Institute of Cancer Medicine and Cell Biology, The University of Sydney, Sydney, NSW, Australia.

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http://dx.doi.org/10.18632/oncotarget.8797DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058675PMC
May 2016

Chronic bacterial infection activates autoreactive B cells and induces isotype switching and autoantigen-driven mutations.

Eur J Immunol 2016 Jan 16;46(1):131-46. Epub 2015 Nov 16.

CNRS UPR 3572 "Immunopathology and Therapeutic Chemistry"/ Laboratory of Excellence Medalis, Molecular and Cellular Biology Institute (IBMC), Strasbourg, France.

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http://dx.doi.org/10.1002/eji.201545810DOI Listing
January 2016

IL-21 and IL-4 Collaborate To Shape T-Dependent Antibody Responses.

J Immunol 2015 Dec 21;195(11):5123-35. Epub 2015 Oct 21.

Department of Immunology, Garvan Institute of Medical Research, Darlinghurst, New South Wales 2010, Australia; and St. Vincent's Clinical School, University of New South Wales, Sydney, New South Wales 2052, Australia

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http://dx.doi.org/10.4049/jimmunol.1501463DOI Listing
December 2015

SnapShot: Interactions between B Cells and T Cells.

Cell 2015 Aug;162(4):926-6.e1

Immunology Division, Garvan Institute of Medical Research, Darlinghurst NSW 2010, Australia; St Vincent's Clinical School, 2010 UNSW, Australia.

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http://dx.doi.org/10.1016/j.cell.2015.07.055DOI Listing
August 2015

Nuclear factor κB-inducing kinase activation as a mechanism of pancreatic β cell failure in obesity.

J Exp Med 2015 Jul 29;212(8):1239-54. Epub 2015 Jun 29.

Transplantation Immunology Group, Immunology Division, Cancer Bioinformatics, Cancer Division, B Cell Biology, Immunology Division, and Beta Cell Regeneration, Diabetes and Metabolism Division, Garvan Institute of Medical Research, Darlinghurst NSW 2010, Australia

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http://dx.doi.org/10.1084/jem.20150218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516791PMC
July 2015

Microbe-dependent lymphatic migration of neutrophils modulates lymphocyte proliferation in lymph nodes.

Nat Commun 2015 May 14;6:7139. Epub 2015 May 14.

1] Immunology Division, The Garvan Institute of Medical Research, 384 Victoria street, Darlinghurst, New South Wales 2010, Australia [2] St Vincent's Clinical School, Faculty of Medicine, UNSW Australia, 390 Victoria street, Darlinghurst, New South Wales 2010, Australia.

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http://dx.doi.org/10.1038/ncomms8139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479041PMC
May 2015

FAS Inactivation Releases Unconventional Germinal Center B Cells that Escape Antigen Control and Drive IgE and Autoantibody Production.

Immunity 2015 May 12;42(5):890-902. Epub 2015 May 12.

Immunology Division, Garvan Institute of Medical Research, 384 Victoria St., Darlinghurst, NSW 2010, Australia; St. Vincent's Clinical School, UNSW Australia, Darlinghurst, NSW 2010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2015.04.010DOI Listing
May 2015

T follicular helper cells have distinct modes of migration and molecular signatures in naive and memory immune responses.

Immunity 2015 Apr 31;42(4):704-18. Epub 2015 Mar 31.

Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, NSW 2010, Australia; St Vincent's Clinical School, Faculty of Medicine, UNSW Australia, 390 Victoria Street, Darlinghurst, NSW 2010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2015.03.002DOI Listing
April 2015

Myeloid cell TRAF3 promotes metabolic inflammation, insulin resistance, and hepatic steatosis in obesity.

Am J Physiol Endocrinol Metab 2015 Mar 27;308(6):E460-9. Epub 2015 Jan 27.

Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan; Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan; and

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http://dx.doi.org/10.1152/ajpendo.00470.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360016PMC
March 2015

LOX-1 unlocks human plasma cell potential.

Authors:
Robert Brink

Immunity 2014 Oct;41(4):507-8

Immunology Division, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst NSW 2010, Australia; St Vincent's Clinical School, UNSW Australia, 390 Victoria Street, Darlinghurst NSW 2010, Australia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10747613140035
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http://dx.doi.org/10.1016/j.immuni.2014.09.019DOI Listing
October 2014

Real-time interactive two-photon photoconversion of recirculating lymphocytes for discontinuous cell tracking in live adult mice.

J Biophotonics 2014 Jun 26;7(6):425-33. Epub 2012 Nov 26.

Immunological Diseases Division, Garvan Institute of Medical Research, Sydney, Australia; St Vincent's Clinical School, Faculty of Medicine, University of New South Wales, Sydney, Australia.

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http://dx.doi.org/10.1002/jbio.201200175DOI Listing
June 2014

The imperfect control of self-reactive germinal center B cells.

Authors:
Robert Brink

Curr Opin Immunol 2014 Jun 28;28:97-101. Epub 2014 Mar 28.

Immunology Division, Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia; St Vincent's Clinical School, UNSW Australia, Darlinghurst, NSW 2010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2014.03.001DOI Listing
June 2014

TRAF3 regulates the effector function of regulatory T cells and humoral immune responses.

J Exp Med 2014 Jan 30;211(1):137-51. Epub 2013 Dec 30.

Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.

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http://dx.doi.org/10.1084/jem.20131019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892978PMC
January 2014

Non-Canonical NF-κB Signaling Initiated by BAFF Influences B Cell Biology at Multiple Junctures.

Front Immunol 2014 Jan 6;4:509. Epub 2014 Jan 6.

Immunology Division, Garvan Institute of Medical Research , Darlinghurst, NSW , Australia ; St. Vincent's Clinical School, University of New South Wales , Darlinghurst, NSW , Australia.

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http://journal.frontiersin.org/article/10.3389/fimmu.2013.00
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http://dx.doi.org/10.3389/fimmu.2013.00509DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880999PMC
January 2014

Diacylglycerol kinase ζ limits B cell antigen receptor-dependent activation of ERK signaling to inhibit early antibody responses.

Sci Signal 2013 Oct 15;6(297):ra91. Epub 2013 Oct 15.

1Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1126/scisignal.2004189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108475PMC
October 2013

Censoring of self-reactive B cells by follicular dendritic cell-displayed self-antigen.

J Immunol 2013 Aug 1;191(3):1082-90. Epub 2013 Jul 1.

Program on Inflammatory Diseases, Sanford-Burnham Medical Research Institute, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.4049/jimmunol.1201569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766769PMC
August 2013

B cell localization: regulation by EBI2 and its oxysterol ligand.

Trends Immunol 2013 Jul 5;34(7):336-41. Epub 2013 Mar 5.

Immunological Diseases Division, Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.

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https://linkinghub.elsevier.com/retrieve/pii/S14714906130001
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http://dx.doi.org/10.1016/j.it.2013.01.007DOI Listing
July 2013

The good, the bad and the ugly - TFH cells in human health and disease.

Nat Rev Immunol 2013 Jun 17;13(6):412-26. Epub 2013 May 17.

Immunology Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales 2010, Australia.

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http://dx.doi.org/10.1038/nri3447DOI Listing
June 2013

The chemotactic receptor EBI2 regulates the homeostasis, localization and immunological function of splenic dendritic cells.

Nat Immunol 2013 May 17;14(5):446-53. Epub 2013 Mar 17.

Immunological Diseases Division, Garvan Institute of Medical Research, Darlinghurst, Australia.

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http://www.nature.com/articles/ni.2555
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http://dx.doi.org/10.1038/ni.2555DOI Listing
May 2013

Elimination of germinal-center-derived self-reactive B cells is governed by the location and concentration of self-antigen.

Immunity 2012 Nov 8;37(5):893-904. Epub 2012 Nov 8.

Immunology Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, NSW 2010, Australia.

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http://linkinghub.elsevier.com/retrieve/pii/S107476131200462
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http://dx.doi.org/10.1016/j.immuni.2012.07.017DOI Listing
November 2012

Affinity-based selection and the germinal center response.

Immunol Rev 2012 May;247(1):11-23

Immunology Research Program, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.

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http://doi.wiley.com/10.1111/j.1600-065X.2012.01118.x
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http://dx.doi.org/10.1111/j.1600-065X.2012.01118.xDOI Listing
May 2012

Hepatic TRAF2 regulates glucose metabolism through enhancing glucagon responses.

Diabetes 2012 Mar 7;61(3):566-73. Epub 2012 Feb 7.

Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.2337/db11-0474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282816PMC
March 2012

A helping hand from neutrophils in T cell-independent antibody responses?

Nat Immunol 2012 Jan 19;13(2):111-3. Epub 2012 Jan 19.

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http://dx.doi.org/10.1038/ni.2214DOI Listing
January 2012

EBI2 operates independently of but in cooperation with CXCR5 and CCR7 to direct B cell migration and organization in follicles and the germinal center.

J Immunol 2011 Nov 23;187(9):4621-8. Epub 2011 Sep 23.

Garvan Institute of Medical Research, Darlinghurst, New South Wales 2010, Australia.

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http://dx.doi.org/10.4049/jimmunol.1101542DOI Listing
November 2011

Identification of Bcl-6-dependent follicular helper NKT cells that provide cognate help for B cell responses.

Nat Immunol 2011 Nov 27;13(1):35-43. Epub 2011 Nov 27.

Department of Pathogens and Immunity, John Curtin School of Medical Research, Australian National University, Canberra, Australia.

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http://dx.doi.org/10.1038/ni.2166DOI Listing
November 2011

B cell priming for extrafollicular antibody responses requires Bcl-6 expression by T cells.

J Exp Med 2011 Jul 27;208(7):1377-88. Epub 2011 Jun 27.

Department of Pathogens and Immunity, John Curtin School of Medical Research, Australian National University, Canberra, Australian Capital Territory 2601, Australia.

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http://dx.doi.org/10.1084/jem.20102065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135363PMC
July 2011

Regulation of T follicular helper cell formation and function by antigen presenting cells.

Curr Opin Immunol 2011 Feb 4;23(1):111-8. Epub 2010 Nov 4.

Immunology Program, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, 2010, NSW, Australia.

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http://dx.doi.org/10.1016/j.coi.2010.10.007DOI Listing
February 2011

New friends for bone marrow plasma cells.

Authors:
Robert Brink

Nat Immunol 2011 Feb;12(2):115-7

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http://www.nature.com/articles/ni0211-115
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http://dx.doi.org/10.1038/ni0211-115DOI Listing
February 2011

The germinal center reaction.

J Allergy Clin Immunol 2010 Nov;126(5):898-907; quiz 908-9

Garvan Institute of Medical Research and St Vincent's Clinical School, University of New South Wales, Darlinghurst, Australia.

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http://dx.doi.org/10.1016/j.jaci.2010.09.007DOI Listing
November 2010

In vivo control of B-cell survival and antigen-specific B-cell responses.

Immunol Rev 2010 Sep;237(1):90-103

Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.

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http://doi.wiley.com/10.1111/j.1600-065X.2010.00942.x
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http://dx.doi.org/10.1111/j.1600-065X.2010.00942.xDOI Listing
September 2010

Lineage-specific transgene expression in hematopoietic cells using a Cre-regulated retroviral vector.

J Immunol Methods 2010 Aug 17;360(1-2):162-6. Epub 2010 Jun 17.

Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst NSW 2010, Australia.

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http://linkinghub.elsevier.com/retrieve/pii/S002217591000172
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http://dx.doi.org/10.1016/j.jim.2010.06.007DOI Listing
August 2010

Control systems and decision making for antibody production.

Nat Immunol 2010 Aug 20;11(8):681-8. Epub 2010 Jul 20.

John Curtin School of Medical Research, The Australian National University, Canberra, Australian Capital Territory, Australia.

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http://www.nature.com/articles/ni.1900
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http://dx.doi.org/10.1038/ni.1900DOI Listing
August 2010

High-affinity B cell receptor ligation by cognate antigen induces cytokine-independent isotype switching.

J Immunol 2010 Jun 14;184(12):6592-9. Epub 2010 May 14.

Walter and Eliza Hall Institute of Medical Research, Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia.

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.0903437
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http://dx.doi.org/10.4049/jimmunol.0903437DOI Listing
June 2010

Micromanaging memory with immunoglobulin microclusters.

Immunity 2010 Jun;32(6):732-3

Immunology Research Program, Garvan Institute of Medical Research, University of New South Wales, Victoria St, Darlinghurst NSW 2010, Australia.

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http://dx.doi.org/10.1016/j.immuni.2010.06.009DOI Listing
June 2010

Guidance of B cells by the orphan G protein-coupled receptor EBI2 shapes humoral immune responses.

Immunity 2009 Aug 16;31(2):259-69. Epub 2009 Jul 16.

Garvan Institute of Medical Research, Darlinghurst NSW 2010, Australia.

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http://dx.doi.org/10.1016/j.immuni.2009.06.016DOI Listing
August 2009

Abdominoplasty with direct resection of deep fat.

Plast Reconstr Surg 2009 May;123(5):1597-603

San Mateo Surgery Center, San Mateo, Calif. 94402, USA.

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https://insights.ovid.com/crossref?an=00006534-200905000-000
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http://dx.doi.org/10.1097/PRS.0b013e3181a07708DOI Listing
May 2009

Follicular helper T cells are required for systemic autoimmunity.

J Exp Med 2009 Mar 16;206(3):561-76. Epub 2009 Feb 16.

Division of Immunology and Genetics, The John Curtin School of Medical Research, Australian National University, Canberra, ACT 2601, Australia.

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http://dx.doi.org/10.1084/jem.20081886DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699132PMC
March 2009

Roquin differentiates the specialized functions of duplicated T cell costimulatory receptor genes CD28 and ICOS.

Immunity 2009 Feb 12;30(2):228-41. Epub 2009 Feb 12.

Division of Immunology and Genetics, John Curtin School of Medical Research, Australian National University, Canberra, Australia.

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http://linkinghub.elsevier.com/retrieve/pii/S107476130900068
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http://dx.doi.org/10.1016/j.immuni.2008.12.015DOI Listing
February 2009

Increased CD4+Foxp3+ T cells in BAFF-transgenic mice suppress T cell effector responses.

J Immunol 2009 Jan;182(2):793-801

Immunology and inflammation Program, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia.

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http://dx.doi.org/10.4049/jimmunol.182.2.793DOI Listing
January 2009

TRAF2 and TRAF3 signal adapters act cooperatively to control the maturation and survival signals delivered to B cells by the BAFF receptor.

Immunity 2008 Mar 28;28(3):391-401. Epub 2008 Feb 28.

Garvan Institute of Medical Research, 384 Victoria St., Darlinghurst NSW 2010, Australia.

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http://linkinghub.elsevier.com/retrieve/pii/S107476130800067
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http://dx.doi.org/10.1016/j.immuni.2008.01.009DOI Listing
March 2008

Visualizing the effects of antigen affinity on T-dependent B-cell differentiation.

Immunol Cell Biol 2008 Jan 20;86(1):31-9. Epub 2007 Nov 20.

Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia.

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http://dx.doi.org/10.1038/sj.icb.7100143DOI Listing
January 2008

B cells and the BAFF/APRIL axis: fast-forward on autoimmunity and signaling.

Curr Opin Immunol 2007 Jun 12;19(3):327-36. Epub 2007 Apr 12.

The Autoimmunity Research Unit, The Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.

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http://linkinghub.elsevier.com/retrieve/pii/S095279150700060
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http://dx.doi.org/10.1016/j.coi.2007.04.008DOI Listing
June 2007

Germinal-center B cells in the zone.

Authors:
Robert Brink

Immunity 2007 May;26(5):552-4

Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst NSW 2010, Australia.

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http://dx.doi.org/10.1016/j.immuni.2007.05.002DOI Listing
May 2007

Regulation of B cell self-tolerance by BAFF.

Authors:
Robert Brink

Semin Immunol 2006 Oct 17;18(5):276-83. Epub 2006 Aug 17.

Centenary Institute of Cancer Medicine and Cell Biology, Newtown, NSW, Australia.

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http://dx.doi.org/10.1016/j.smim.2006.04.003DOI Listing
October 2006

High affinity germinal center B cells are actively selected into the plasma cell compartment.

J Exp Med 2006 Oct 9;203(11):2419-24. Epub 2006 Oct 9.

Centenary Institute of Cancer Medicine and Cell Biology, Newtown NSW 2042, Australia.

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http://dx.doi.org/10.1084/jem.20061254DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118125PMC
October 2006

Antigen recognition strength regulates the choice between extrafollicular plasma cell and germinal center B cell differentiation.

J Exp Med 2006 Apr 10;203(4):1081-91. Epub 2006 Apr 10.

Centenary Institute of Cancer Medicine and Cell Biology, Newtown NSW 2042, Australia.

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http://dx.doi.org/10.1084/jem.20060087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118299PMC
April 2006

Tumor necrosis factor receptor 2 (TNFR2) signaling is negatively regulated by a novel, carboxyl-terminal TNFR-associated factor 2 (TRAF2)-binding site.

J Biol Chem 2005 Sep 14;280(36):31572-81. Epub 2005 Jul 14.

Centenary Institute of Cancer Medicine and Cell Biology, Locked Bag No. 6, Newtown, New South Wales 2042, Australia.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M504849200
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http://dx.doi.org/10.1074/jbc.M504849200DOI Listing
September 2005

Altered migration, recruitment, and somatic hypermutation in the early response of marginal zone B cells to T cell-dependent antigen.

J Immunol 2005 Apr;174(8):4567-78

Centenary Institute of Cancer Medicine and Cell Biology, Newtown, New South Wales, Australia.

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http://dx.doi.org/10.4049/jimmunol.174.8.4567DOI Listing
April 2005

TRAF2 differentially regulates the canonical and noncanonical pathways of NF-kappaB activation in mature B cells.

Immunity 2004 Nov;21(5):629-42

Centenary Institute of Cancer Medicine and Cell Biology, Locked Bag No. 6, Newtown, NSW 2042, Australia.

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http://dx.doi.org/10.1016/j.immuni.2004.09.011DOI Listing
November 2004

Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches.

Immunity 2004 Jun;20(6):785-98

Centenary Institute of Cancer Medicine and Cell Biology, Locked Bag Number 6, Newtown, New South Wales 2042, Australia.

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http://dx.doi.org/10.1016/j.immuni.2004.05.010DOI Listing
June 2004