Dr Robert Bowser, PhD - Barrow Neurological Institute - Professor and Chair

Dr Robert Bowser

PhD

Barrow Neurological Institute

Professor and Chair

Phoenix, AZ | United States

Main Specialties: Neurology

Additional Specialties: Neurobiology

Dr Robert Bowser, PhD - Barrow Neurological Institute - Professor and Chair

Dr Robert Bowser

PhD

Introduction

Primary Affiliation: Barrow Neurological Institute - Phoenix, AZ , United States

Specialties:

Additional Specialties:

Publications

89Publications

2204Reads

-Profile Views

1611PubMed Central Citations

Fluid-Based Biomarkers for Amyotrophic Lateral Sclerosis.

Neurotherapeutics 2017 01;14(1):119-134

Department of Neurology, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, 350 West Thomas Road, Phoenix, AZ, 85013, USA.

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http://dx.doi.org/10.1007/s13311-016-0503-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233638PMC
January 2017
41 Reads
7 Citations

Expression of Carbonic Anhydrase I in Motor Neurons and Alterations in ALS.

Int J Mol Sci 2016 Nov 1;17(11). Epub 2016 Nov 1.

Department of Biological Sciences, Xi'an Jiaotong-Liverpool University, Suzhou 215123, China.

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http://dx.doi.org/10.3390/ijms17111820DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133821PMC
November 2016
5 Reads
2.862 Impact Factor

Immunoprecipitation and mass spectrometry defines an extensive RBM45 protein-protein interaction network.

Brain Res 2016 09 12;1647:79-93. Epub 2016 Mar 12.

Divisions of Neurology and Neurobiology, Barrow Neurological Institute, St. Joseph׳s Hospital and Medical Center, Phoenix, AZ 85013, USA; University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA. Electronic address:

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http://dx.doi.org/10.1016/j.brainres.2016.02.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5152586PMC
September 2016
51 Reads
5 Citations
2.843 Impact Factor

Attenuated traumatic axonal injury and improved functional outcome after traumatic brain injury in mice lacking Sarm1.

Brain 2016 Apr 11;139(Pt 4):1094-105. Epub 2016 Feb 11.

1 Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01655, USA.

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http://dx.doi.org/10.1093/brain/aww001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006226PMC
April 2016
20 Reads
14 Citations
9.200 Impact Factor

Reply.

Ann Neurol 2016 Feb 19;79(2):334. Epub 2016 Jan 19.

Department of Neurology, University of Miami, Miami, FL.

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http://dx.doi.org/10.1002/ana.24586DOI Listing
February 2016
19 Reads
9.980 Impact Factor

Sustainability in a Hospital-Based Biobank and University-Based DNA Biorepository: Strategic Roadmaps.

Biopreserv Biobank 2015 Dec;13(6):401-9

3 DNASU Plasmid Repository, Virginia G. Piper Center for Personalized Diagnostics, Biodesign Institute, Arizona State University , Tempe, Arizona.

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http://dx.doi.org/10.1089/bio.2015.0076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724783PMC
December 2015
7 Reads
5 Citations

Letter to the editor on "Exposure to hazardous air pollutants and the risk of amyotrophic lateral sclerosis".

Environ Pollut 2015 Dec 19;207:432-3. Epub 2015 May 19.

Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA. Electronic address:

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http://dx.doi.org/10.1016/j.envpol.2015.05.014DOI Listing
December 2015
12 Reads
4.143 Impact Factor

Label-Free LC-MS/MS Proteomic Analysis of Cerebrospinal Fluid Identifies Protein/Pathway Alterations and Candidate Biomarkers for Amyotrophic Lateral Sclerosis.

J Proteome Res 2015 Nov 8;14(11):4486-501. Epub 2015 Oct 8.

Departments of Neurology and Neurobiology, Barrow Neurological Institute , NRC427, 350 West Thomas Road, Phoenix, Arizona 85013, United States.

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http://dx.doi.org/10.1021/acs.jproteome.5b00804DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592736PMC
November 2015
55 Reads
14 Citations
4.250 Impact Factor

Amyotrophic lateral sclerosis: Is the spinal fluid pathway involved in seeding and spread?

Med Hypotheses 2015 Nov 20;85(5):576-83. Epub 2015 Jul 20.

Barrow Neurological Institute, Gregory W. Fulton ALS and Neuromuscular Research Center, 350 West Thomas Rd., Phoenix, AZ 85013, United States.

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http://dx.doi.org/10.1016/j.mehy.2015.07.014DOI Listing
November 2015
18 Reads
2 Citations
1.152 Impact Factor

To travel or not to travel: The modern day struggle of the academic researcher.

Ann Neurol 2015 Nov 18;78(5):667-9. Epub 2015 Sep 18.

Department of Neurology, University of Miami, Miller School of Medicine, Miami, FL.

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http://dx.doi.org/10.1002/ana.24516DOI Listing
November 2015
5 Reads
9.980 Impact Factor

RBM45 homo-oligomerization mediates association with ALS-linked proteins and stress granules.

Sci Rep 2015 Sep 22;5:14262. Epub 2015 Sep 22.

Divisions of Neurology and Neurobiology, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona 85013, USA.

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http://dx.doi.org/10.1038/srep14262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585734PMC
September 2015
8 Reads
5 Citations
5.080 Impact Factor

Total protein is an effective loading control for cerebrospinal fluid western blots.

J Neurosci Methods 2015 Aug 22;251:72-82. Epub 2015 May 22.

Departments of Neurobiology and Neurology, St. Joseph's Hospital and Medical Center and Barrow Neurological Institute, 350 West Thomas Road, Phoenix, AZ 85013, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jneumeth.2015.05.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540354PMC
August 2015
3 Reads
9 Citations
2.025 Impact Factor

RBM45 Modulates the Antioxidant Response in Amyotrophic Lateral Sclerosis through Interactions with KEAP1.

Mol Cell Biol 2015 Jul 4;35(14):2385-99. Epub 2015 May 4.

Divisions of Neurology and Neurobiology, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA

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http://dx.doi.org/10.1128/MCB.00087-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475920PMC
July 2015
41 Reads
8 Citations
4.780 Impact Factor

Use of biomarkers in ALS drug development and clinical trials.

Brain Res 2015 May 24;1607:94-107. Epub 2014 Oct 24.

Divisions of Neurology and Neurobiology, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ 85013, USA. Electronic address:

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http://dx.doi.org/10.1016/j.brainres.2014.10.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809521PMC
May 2015
1 Read
7 Citations
2.843 Impact Factor

Environmental and occupational risk factors for amyotrophic lateral sclerosis: a case-control study.

Neurodegener Dis 2014 12;14(1):31-8. Epub 2013 Nov 12.

Department of Neurosciences, College of Medicine, Medical University of South Carolina, Charleston, S.C., USA.

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http://dx.doi.org/10.1159/000355344DOI Listing
February 2015
30 Reads
18 Citations
3.511 Impact Factor

Exposure to hazardous air pollutants and the risk of amyotrophic lateral sclerosis.

Environ Pollut 2015 Feb 23;197:181-186. Epub 2014 Dec 23.

Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, 15261, USA. Electronic address:

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http://dx.doi.org/10.1016/j.envpol.2014.12.010DOI Listing
February 2015
40 Reads
11 Citations
4.143 Impact Factor

Futsch/MAP1B mRNA is a translational target of TDP-43 and is neuroprotective in a Drosophila model of amyotrophic lateral sclerosis.

J Neurosci 2014 Nov;34(48):15962-74

Departments of Molecular and Cellular Biology, Neuroscience, and Neurology, University of Arizona, Tucson, Arizona 85721, and

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http://dx.doi.org/10.1523/JNEUROSCI.2526-14.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244467PMC
November 2014
63 Reads
33 Citations
6.344 Impact Factor

Biomarker time out.

Mult Scler 2014 Oct 20;20(12):1560-3. Epub 2014 Feb 20.

Department of Neurology, MS Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1177/1352458514524999DOI Listing
October 2014
7 Reads
4.822 Impact Factor

Plasma metabolomic biomarker panel to distinguish patients with amyotrophic lateral sclerosis from disease mimics.

Amyotroph Lateral Scler Frontotemporal Degener 2014 Sep 1;15(5-6):362-70. Epub 2014 Jul 1.

Metabolon, Inc , Durham , North Carolina.

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http://dx.doi.org/10.3109/21678421.2014.908311DOI Listing
September 2014
80 Reads
9 Citations
2.591 Impact Factor

Novel Death Defying Domain in Met entraps the active site of caspase-3 and blocks apoptosis in hepatocytes.

Hepatology 2014 May 1;59(5):2010-21. Epub 2014 Apr 1.

Department of Pathology, University of Pittsburgh, School of Medicine, Pittsburgh, PA.

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http://dx.doi.org/10.1002/hep.26769DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975826PMC
May 2014
9 Reads
6 Citations
11.055 Impact Factor

Therapeutic neuroprotective agents for amyotrophic lateral sclerosis.

Cell Mol Life Sci 2013 Dec 18;70(24):4729-45. Epub 2013 Jul 18.

Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1007/s00018-013-1415-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172456PMC
December 2013
7 Reads
12 Citations
5.810 Impact Factor

Post-lumbar puncture headache is reduced with use of atraumatic needles in ALS.

Amyotroph Lateral Scler Frontotemporal Degener 2013 Dec 8;14(7-8):632-4. Epub 2013 Jul 8.

Department of Neurology, University of Massachusetts, Memorial Medical Center , Worcester, Massachusetts.

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http://dx.doi.org/10.3109/21678421.2013.808227DOI Listing
December 2013
3 Reads
1 Citation
2.591 Impact Factor

Genetic variation in ESR2 and estrogen receptor-beta expression in lung tumors.

Cancer Epidemiol 2013 Aug 23;37(4):518-22. Epub 2013 Apr 23.

Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh and University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1016/j.canep.2013.03.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684046PMC
August 2013
40 Reads
1 Citation
2.560 Impact Factor

Mechanisms, models and biomarkers in amyotrophic lateral sclerosis.

Amyotroph Lateral Scler Frontotemporal Degener 2013 May;14 Suppl 1:19-32

Nuffield Department of Clinical Neurosciences, University of Oxford, UK.

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http://dx.doi.org/10.3109/21678421.2013.778554DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284067PMC
May 2013
47 Reads
39 Citations
2.591 Impact Factor

ALS Untangled No. 20: the Deanna protocol.

Amyotroph Lateral Scler Frontotemporal Degener 2013 May 2;14(4):319-23. Epub 2013 May 2.

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http://dx.doi.org/10.3109/21678421.2013.788405DOI Listing
May 2013
91 Reads
4 Citations
2.591 Impact Factor

pNfH is a promising biomarker for ALS.

Amyotroph Lateral Scler Frontotemporal Degener 2013 Mar 22;14(2):146-9. Epub 2012 Oct 22.

King's Health Partners Centre for Neurodegeneration Research, Institute of Psychiatry, Kings College London, UK.

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http://dx.doi.org/10.3109/21678421.2012.729596DOI Listing
March 2013
9 Reads
16 Citations
2.591 Impact Factor

Reactive astrocytes secrete lcn2 to promote neuron death.

Proc Natl Acad Sci U S A 2013 Mar 19;110(10):4069-74. Epub 2013 Feb 19.

Department of Pathology, Anatomy, and Cell Biology, Thomas Jefferson University, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1073/pnas.1218497110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3593910PMC
March 2013
28 Reads
54 Citations
9.810 Impact Factor

Retinoid signaling alterations in amyotrophic lateral sclerosis.

Am J Neurodegener Dis 2012 23;1(2):130-45. Epub 2012 Jul 23.

Department of Pathology, University of Pittsburgh School of Medicine 200 Lothrop Street, Pittsburgh, PA USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560459PMC
February 2013
13 Reads
10 Citations

Pesticide exposure as a risk factor for amyotrophic lateral sclerosis: a meta-analysis of epidemiological studies: pesticide exposure as a risk factor for ALS.

Environ Res 2012 Aug 20;117:112-9. Epub 2012 Jul 20.

Department of Neurosciences, College of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.

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http://dx.doi.org/10.1016/j.envres.2012.06.007DOI Listing
August 2012
56 Reads
17 Citations
4.373 Impact Factor

Survival outcomes in endometrial cancer patients are associated with CXCL12 and estrogen receptor expression.

Int J Cancer 2012 Jul 3;131(2):E114-21. Epub 2012 Jan 3.

Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852-7234, USA.

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http://dx.doi.org/10.1002/ijc.27317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291748PMC
July 2012
14 Reads
6 Citations
5.085 Impact Factor

Neuroprotection for amyotrophic lateral sclerosis: role of stem cells, growth factors, and gene therapy.

Cent Nerv Syst Agents Med Chem 2012 Mar;12(1):15-27

Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Department of Neurosurgery, Boston, Massachusetts 02115, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170803PMC
http://dx.doi.org/10.2174/187152412800229152DOI Listing
March 2012
5 Reads
8 Citations

Biochemical alterations associated with ALS.

Amyotroph Lateral Scler 2012 Jan 25;13(1):110-8. Epub 2011 Nov 25.

Metabolon Inc., North Carolina, USA.

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http://dx.doi.org/10.3109/17482968.2011.619197DOI Listing
January 2012
48 Reads
15 Citations

Biomarkers in amyotrophic lateral sclerosis: opportunities and limitations.

Nat Rev Neurol 2011 Oct 11;7(11):631-8. Epub 2011 Oct 11.

Division of Neurology, Barrow Neurological Institute, St Joseph's Hospital and Medical Center, 350 West Thomas Street, Phoenix, AZ 85213, USA.

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http://dx.doi.org/10.1038/nrneurol.2011.151DOI Listing
October 2011
31 Reads
24 Citations
15.360 Impact Factor

Outcome of lumbar epidural steroid injection is predicted by assay of a complex of fibronectin and aggrecan from epidural lavage.

Spine (Phila Pa 1976) 2011 Aug;36(18):1464-9

Department of Orthopaedic Surgery, Stanford University, Palo Alto, CA, USA.

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http://dx.doi.org/10.1097/BRS.0b013e3181f40e88DOI Listing
August 2011
9 Reads
5 Citations
2.300 Impact Factor

Comparison of survival outcomes between patients with malignant mixed mullerian tumors and high-grade endometrioid, clear cell, and papillary serous endometrial cancers.

Int J Gynecol Cancer 2011 Jul;21(5):877-84

Division of Cancer Prevention and Population Science, University of Pittsburgh Cancer Institute, Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, and Department of Obstetrics and Gynecologic Oncology, Magee-Women's Hospital of UPMC Health System, Pittsburgh, PA 15232, USA.

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http://dx.doi.org/10.1097/IGC.0b013e31821a62ddDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827731PMC
July 2011
24 Reads
5 Citations
1.950 Impact Factor

Combination of neurofilament heavy chain and complement C3 as CSF biomarkers for ALS.

J Neurochem 2011 May 21;117(3):528-37. Epub 2011 Mar 21.

Department of Clinical Neuroscience, King's College London, King's Health Partners, MRC Centre for Neurodegeneration Research, London, UK.

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http://dx.doi.org/10.1111/j.1471-4159.2011.07224.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076545PMC
May 2011
3 Reads
32 Citations
4.281 Impact Factor

Identification of a novel fibronectin-aggrecan complex in the synovial fluid of knees with painful meniscal injury.

J Bone Joint Surg Am 2011 Feb;93(4):336-40

Jupiter Outpatient Medical Center, Jupiter, Florida, USA.

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http://dx.doi.org/10.2106/JBJS.J.00718DOI Listing
February 2011
34 Reads
1 Citation
5.280 Impact Factor

Proposed BioRepository platform solution for the ALS research community.

Amyotroph Lateral Scler 2011 Jan 6;12(1):11-6. Epub 2010 Dec 6.

Neurology Clinical Trials Unit, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA.

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http://dx.doi.org/10.3109/17482968.2010.539233DOI Listing
January 2011
49 Reads
4 Citations

Cystatin C: a candidate biomarker for amyotrophic lateral sclerosis.

PLoS One 2010 Dec 9;5(12):e15133. Epub 2010 Dec 9.

Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0015133PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000338PMC
December 2010
19 Reads
25 Citations
3.234 Impact Factor

A pilot trial of memantine and riluzole in ALS: correlation to CSF biomarkers.

Amyotroph Lateral Scler 2010 Dec 14;11(6):514-9. Epub 2010 Sep 14.

PNA Center for Neurologic Research, 5090 N 40th St., Phoenix, AZ 85018, USA.

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http://dx.doi.org/10.3109/17482968.2010.513052DOI Listing
December 2010
16 Reads
8 Citations

Factors associated with Type I and Type II endometrial cancer.

Cancer Causes Control 2010 Nov 14;21(11):1851-6. Epub 2010 Jul 14.

Division of Cancer Prevention and Population Science, University of Pittsburgh Cancer Institute, 5150 Centre Avenue, Suite 4-C, Pittsburgh, PA 15232, USA.

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http://dx.doi.org/10.1007/s10552-010-9612-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2962676PMC
November 2010
40 Reads
41 Citations
2.735 Impact Factor

Carbonic anhydrase I is recognized by an SOD1 antibody upon biotinylation of human spinal cord extracts.

Int J Mol Sci 2010 Oct 20;11(10):4051-62. Epub 2010 Oct 20.

Department of Neuroscience, California Pacific Medical Center Research Institute, 475 Brannan Street, San Francisco, CA 94107, USA; E-Mail: (M.L.).

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http://dx.doi.org/10.3390/ijms11104051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996799PMC
October 2010
59 Reads
3 Citations
2.862 Impact Factor

Discovery and verification of amyotrophic lateral sclerosis biomarkers by proteomics.

Muscle Nerve 2010 Jul;42(1):104-11

Department of Pathology, University of Pittsburgh School of Medicine, BST S-420, 200 Lothrop Street, Pittsburgh, Pennsylvania 15261, USA.

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http://dx.doi.org/10.1002/mus.21683DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2975276PMC
July 2010
3 Reads
32 Citations
2.283 Impact Factor

The application of biomarkers in clinical trials for motor neuron disease.

Biomark Med 2010 Apr;4(2):281-97

Department of Clinical Neurosciences, Institute of Psychiatry, Kings College London, UK.

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http://dx.doi.org/10.2217/bmm.09.71DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897051PMC
April 2010
6 Reads
8 Citations
2.860 Impact Factor

Paxillin and hydrogen peroxide-inducible clone 5 expression and distribution in control and Alzheimer disease hippocampi.

J Neuropathol Exp Neurol 2010 Apr;69(4):356-71

Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA.

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http://dx.doi.org/10.1097/NEN.0b013e3181d53d98DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869219PMC
April 2010
47 Reads
6 Citations
3.800 Impact Factor

Transgenic rat model of neurodegeneration caused by mutation in the TDP gene.

PLoS Genet 2010 Mar 26;6(3):e1000887. Epub 2010 Mar 26.

Department of Pathology, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1000887DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845661PMC
March 2010
57 Reads
86 Citations

p53 and Cell Cycle Proteins Participate in Spinal Motor Neuron Cell Death in ALS.

Open Pathol J 2010 Jan;4:11-22

Department of Pathology, Pittsburgh, PA, USA.

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http://dx.doi.org/10.2174/1874375701004010011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092395PMC
January 2010
2 Reads
10 Citations

Altered subcellular distribution of c-Abl in Alzheimer's disease.

J Alzheimers Dis 2009 ;17(2):409-22

Department of Pathology, University of Pittsburgh, School of Medicine, BST S-420, 200 Lothrop Street, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.3233/JAD-2009-1062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829466PMC
December 2009
1 Read
20 Citations
4.151 Impact Factor

Applying proteomics to the diagnosis and treatment of ALS and related diseases.

Muscle Nerve 2009 Nov;40(5):753-62

Department of Pathology, University of Pittsburgh School of Medicine, BST S-420, 200 Lothrop Street, Pittsburgh, Pennsylvania 15261, USA.

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http://dx.doi.org/10.1002/mus.21488DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836583PMC
November 2009
5 Reads
10 Citations
2.283 Impact Factor

Knowledge-based variable selection for learning rules from proteomic data.

BMC Bioinformatics 2009 Sep 17;10 Suppl 9:S16. Epub 2009 Sep 17.

Department of Biomedical Informatics, University of Pittsburgh, 200 Meyran Ave, Parkvale M-183, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1186/1471-2105-10-S9-S16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745687PMC
September 2009
24 Reads
2 Citations
2.580 Impact Factor

Using a novel resource to decrease proteomic biomarker identification time.

AMIA Annu Symp Proc 2008 Nov 6:1033. Epub 2008 Nov 6.

Department of Biomedical Informatics, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.

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November 2008
12 Reads

Protein biomarkers for amyotrophic lateral sclerosis.

Expert Rev Proteomics 2008 Apr;5(2):249-62

Department of Pathology, Center for ALS Research, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.1586/14789450.5.2.249DOI Listing
April 2008
2 Reads
11 Citations
2.900 Impact Factor

Comparative proteomic profiling of cerebrospinal fluid between living and post mortem ALS and control subjects.

Amyotroph Lateral Scler 2007 Dec 3;8(6):373-9. Epub 2007 Aug 3.

Neurogenetics Branch, National Institute of Neurological Disorders and Stroke, National Institute of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1080/17482960701549681DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829467PMC
December 2007
9 Reads
4 Citations

Common molecular signature in SOD1 for both sporadic and familial amyotrophic lateral sclerosis.

Proc Natl Acad Sci U S A 2007 Jul 16;104(30):12524-9. Epub 2007 Jul 16.

Bioconformatics Laboratory and Department of Neuroscience, California Pacific Medical Center Research Institute, San Francisco, CA 94107, USA.

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http://dx.doi.org/10.1073/pnas.0705044104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1941502PMC
July 2007
21 Reads
76 Citations
9.810 Impact Factor

Increased expression of p130 in Alzheimer disease.

Neurochem Res 2007 Apr-May;32(4-5):639-44. Epub 2006 Sep 28.

Department of Pathology, Case Western Reserve University, 2103 Cornell Road, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1007/s11064-006-9146-3DOI Listing
May 2007
21 Reads
9 Citations
2.593 Impact Factor

Focal adhesions regulate Abeta signaling and cell death in Alzheimer's disease.

Biochim Biophys Acta 2007 Apr 30;1772(4):438-45. Epub 2006 Nov 30.

Department of Pathology, University of Pittsburgh School of Medicine, BST S-420, 200 Lothrop St., Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.1016/j.bbadis.2006.11.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1876750PMC
April 2007
23 Citations

Plasma and cerebrospinal fluid-based protein biomarkers for motor neuron disease.

Mol Diagn Ther 2006 ;10(5):281-92

Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA.

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http://dx.doi.org/10.1007/BF03256203DOI Listing
December 2006
9 Reads
5 Citations
2.891 Impact Factor

Functional repression of cAMP response element in 6-hydroxydopamine-treated neuronal cells.

J Biol Chem 2006 Jun 18;281(26):17870-81. Epub 2006 Apr 18.

Department of Pathology, Division of Neuropathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1074/jbc.M602632200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1876691PMC
June 2006
7 Reads
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4.573 Impact Factor

Biomarkers for amyotrophic lateral sclerosis.

Expert Rev Mol Diagn 2006 May;6(3):387-98

University of Pittsburgh, Department of Pathology, School of Medicine, ST S-420, 200 Lothrop Street, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.1586/14737159.6.3.387DOI Listing
May 2006
3 Reads
9 Citations
3.520 Impact Factor

Proteomic profiling of cerebrospinal fluid identifies biomarkers for amyotrophic lateral sclerosis.

J Neurochem 2005 Dec;95(5):1461-71

Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2005.03478.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1540444PMC
December 2005
41 Reads
59 Citations
4.281 Impact Factor

DNA damage induces cdk2 protein levels and histone H2B phosphorylation in SH-SY5Y neuroblastoma cells.

J Alzheimers Dis 2005 Sep;8(1):7-21

Department of Pathology, Division of Neuropathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.3233/jad-2005-8102DOI Listing
September 2005
3 Reads
3 Citations
4.151 Impact Factor

Fetal Alz-50 clone 1 interacts with the human orthologue of the Kelch-like Ech-associated protein.

Biochemistry 2004 Sep;43(38):12113-22

Department of Pathology, University of Pennsylvania, 4010 Locust Street, Philadelphia, Pennsylvania 19104-6030, USA.

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http://dx.doi.org/10.1021/bi0494166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670950PMC
September 2004
12 Reads
10 Citations
3.020 Impact Factor

PhD graduate training programs in pathology: 2003 report from the American Society for Investigative Pathology workshop on pathology graduate education.

Hum Pathol 2004 Jul;35(7):785-9

Department of Pathology, University of Iowa Health Care, Iowa City, IA, USA.

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July 2004
2 Reads
2.770 Impact Factor

Alzheimer disease pathology in amyotrophic lateral sclerosis.

Acta Neuropathol 2004 Jun 16;107(6):515-22. Epub 2004 Mar 16.

A-506, Presbyterian University Hospital, 200 Lothrop Street, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1007/s00401-004-0843-1DOI Listing
June 2004
12 Reads
9 Citations
10.762 Impact Factor

Ectopic localization of phosphorylated histone H3 in Alzheimer's disease: a mitotic catastrophe?

Acta Neuropathol 2003 May 26;105(5):524-8. Epub 2003 Feb 26.

Institute of Pathology, Case Western Reserve University, 2085 Adelbert Road, Cleveland, OH 44106, USA.

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41 Reads
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10.762 Impact Factor

Von Willebrand factor promoter targets the expression of amyloid beta protein precursor to brain vascular endothelial cells of transgenic mice.

J Alzheimers Dis 2003 Apr;5(2):149-58

Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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April 2003
10 Reads
3 Citations
4.151 Impact Factor

Alterations in G(1) to S phase cell-cycle regulators during amyotrophic lateral sclerosis.

Am J Pathol 2003 Mar;162(3):823-35

Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA.

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http://dx.doi.org/10.1016/S0002-9440(10)63879-5DOI Listing
March 2003
2 Reads
40 Citations
4.591 Impact Factor

Altered expression and distribution of FAC1 during NGF-induced neurite outgrowth of PC12 cells.

Neuroreport 2003 Mar;14(3):449-52

Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.1097/00001756-200303030-00030DOI Listing
March 2003
28 Reads
3 Citations
1.644 Impact Factor

The 12th International Symposium on ALS/MND: scientific advancements in amyotrophic lateral sclerosis. November 18-20, 2001, Oakland, Calif.

Brain Pathol 2002 Oct;12(4):511-4

Department of Pathology, University of Pittsburgh School of Medicine, PA 15261, USA.

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http://dx.doi.org/10.1111/j.1750-3639.2002.tb00469.xDOI Listing
October 2002
3 Reads
3.840 Impact Factor

Cell cycle proteins in Alzheimer's disease: plenty of wheels but no cycle.

J Alzheimers Dis 2002 Jun;4(3):249-54

Department of Pathology, BST S-420, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.3233/jad-2002-4316DOI Listing
June 2002
30 Reads
27 Citations
4.151 Impact Factor

Altered distribution of cell cycle transcriptional regulators during Alzheimer disease.

J Neuropathol Exp Neurol 2002 Apr;61(4):358-67

Department of Pathology, University of Pittsburgh School of Medicine, Pennsylvania 15261, USA.

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http://dx.doi.org/10.1093/jnen/61.4.358DOI Listing
April 2002
2 Reads
26 Citations
3.800 Impact Factor

Hyperphosphorylation of the retinoblastoma gene product and altered subcellular distribution of E2F-1 during Alzheimer's disease and amyotrophic lateral sclerosis.

J Alzheimers Dis 2001 Aug;3(4):377-385

Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.3233/jad-2001-3403DOI Listing
August 2001
2 Reads
22 Citations
4.151 Impact Factor

Increased Cyclin G1 Immunoreactivity During Alzheimer's Disease.

J Alzheimers Dis 1999 Dec;1(6):409-417

Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.

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December 1999
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3 Citations
4.151 Impact Factor

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