Publications by authors named "Robert Bowser"

100Publications

Generation of two induced pluripotent stem cell (iPSC) lines from an ALS patient with simultaneous mutations in KIF5A and MATR3 genes.

Stem Cell Res 2020 Dec 24;50:102141. Epub 2020 Dec 24.

Department of Neurobiology, Gregory W Fulton ALS Research Center, Barrow Neurological Institute, 350 W Thomas Road, Phoenix, AZ 85013, USA.

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December 2020

Identification of a pathogenic intronic KIF5A mutation in an ALS-FTD kindred.

Neurology 2020 12 19;95(22):1015-1018. Epub 2020 Oct 19.

From the Neuromuscular Diseases Research Section (S.S-A, B.J.T.), Laboratory of Neurogenetics, NIA, NIH; Department of Anatomy (C.L.D.), Physiology & Genetics, Uniformed Services University of the Health Sciences; The American Genome Center (C.L.D., C.A., D.N.H., M.D.W.), Collaborative Health Initiative Research Program, Uniformed Services University of the Health Sciences; Computational Biology Core (J.D.), Laboratory of Neurogenetics, NIA, NIH, Bethesda, MD; Rita Levi Montalcini Department of Neuroscience (A.C.), University of Turin, Italy and AOU Città della Salute e della Scienza, Turin, Italy; Division of Neurology and Neurobiology (R. Bowser), Barrow Neurological Institute, Phoenix, AZ; Department of Neurology (E.P.P.), Neuromuscular Center, Neurological Institute, Cleveland Clinic, OH; Department of Neurology (R. Bedlack), Duke University and the Durham VA Medical Center, NC; and Department of Neurology (B.J.T.), Johns Hopkins University, Baltimore, MD.

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December 2020

RBM45 associates with nuclear stress bodies and forms nuclear inclusions during chronic cellular stress and in neurodegenerative diseases.

Acta Neuropathol Commun 2020 06 26;8(1):91. Epub 2020 Jun 26.

Departments of Neurobiology and Neurology, Barrow Neurological Institute, Phoenix, AZ, USA.

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June 2020

Intravenously Administered, Retinoid Activating Nanoparticles Increase Lifespan and Reduce Neurodegeneration in the SOD1 Mouse Model of ALS.

Front Bioeng Biotechnol 2020 27;8:224. Epub 2020 Mar 27.

Barrow Brain Tumor Research Center, Barrow Neurological Institute, Phoenix, AZ, United States.

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March 2020

Cross-sectional and longitudinal measures of chitinase proteins in amyotrophic lateral sclerosis and expression of CHI3L1 in activated astrocytes.

J Neurol Neurosurg Psychiatry 2020 04 14;91(4):350-358. Epub 2020 Jan 14.

Department of Neurobiology, Barrow Neurological Institute, Phoenix, Arizona, USA

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April 2020

IL6 receptorAla variant and trans-signaling are disease modifiers in amyotrophic lateral sclerosis.

Neurol Neuroimmunol Neuroinflamm 2019 11 14;6(6):e631. Epub 2019 Oct 14.

From the Department of Neurobiology and Anatomy (M.W.-K., M.R., J.S., P.A., M.M., C.M.); Department of Neurology (J.C., M. Cartwright); and Department of Biochemistry (G.A.H.), Wake Forest School of Medicine; Division of Public Health (C.L.), Department of Biostatistical Sciences, Wake Forest School of Medicine; Departments of Neurology and Neurobiology (R.B.), Barrow Neurological Institute & St. Joseph's Hospital and Medical Center; Department of Neurology (M. Cudkowicz), Neurological Clinical Research Institute, Massachusetts General Hospital, Harvard Medical School; and Current Address Department of Pediatrics (M.M.), Nationwide Children's Hospital, Columbus OH.

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November 2019

Neurofilaments in pre-symptomatic ALS and the impact of genotype.

Amyotroph Lateral Scler Frontotemporal Degener 2019 11 21;20(7-8):538-548. Epub 2019 Aug 21.

Neuroscience Center, Blizard, Institute of Cell and Molecular Medicine, Barts & the London School of Medicine & Dentistry , London , UK.

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November 2019

RNA Nucleocytoplasmic Transport Defects in Neurodegenerative Diseases.

Adv Neurobiol 2018 ;20:85-101

Department of Neurobiology, Barrow Neurological Institute, Phoenix, AZ, USA.

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October 2018

Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.

Authors:
Aude Nicolas Kevin P Kenna Alan E Renton Nicola Ticozzi Faraz Faghri Ruth Chia Janice A Dominov Brendan J Kenna Mike A Nalls Pamela Keagle Alberto M Rivera Wouter van Rheenen Natalie A Murphy Joke J F A van Vugt Joshua T Geiger Rick A Van der Spek Hannah A Pliner Shankaracharya Bradley N Smith Giuseppe Marangi Simon D Topp Yevgeniya Abramzon Athina Soragia Gkazi John D Eicher Aoife Kenna Gabriele Mora Andrea Calvo Letizia Mazzini Nilo Riva Jessica Mandrioli Claudia Caponnetto Stefania Battistini Paolo Volanti Vincenzo La Bella Francesca L Conforti Giuseppe Borghero Sonia Messina Isabella L Simone Francesca Trojsi Fabrizio Salvi Francesco O Logullo Sandra D'Alfonso Lucia Corrado Margherita Capasso Luigi Ferrucci Cristiane de Araujo Martins Moreno Sitharthan Kamalakaran David B Goldstein Aaron D Gitler Tim Harris Richard M Myers Hemali Phatnani Rajeeva Lochan Musunuri Uday Shankar Evani Avinash Abhyankar Michael C Zody Julia Kaye Steven Finkbeiner Stacia K Wyman Alex LeNail Leandro Lima Ernest Fraenkel Clive N Svendsen Leslie M Thompson Jennifer E Van Eyk James D Berry Timothy M Miller Stephen J Kolb Merit Cudkowicz Emily Baxi Michael Benatar J Paul Taylor Evadnie Rampersaud Gang Wu Joanne Wuu Giuseppe Lauria Federico Verde Isabella Fogh Cinzia Tiloca Giacomo P Comi Gianni Sorarù Cristina Cereda Philippe Corcia Hannu Laaksovirta Liisa Myllykangas Lilja Jansson Miko Valori John Ealing Hisham Hamdalla Sara Rollinson Stuart Pickering-Brown Richard W Orrell Katie C Sidle Andrea Malaspina John Hardy Andrew B Singleton Janel O Johnson Sampath Arepalli Peter C Sapp Diane McKenna-Yasek Meraida Polak Seneshaw Asress Safa Al-Sarraj Andrew King Claire Troakes Caroline Vance Jacqueline de Belleroche Frank Baas Anneloor L M A Ten Asbroek José Luis Muñoz-Blanco Dena G Hernandez Jinhui Ding J Raphael Gibbs Sonja W Scholz Mary Kay Floeter Roy H Campbell Francesco Landi Robert Bowser Stefan M Pulst John M Ravits Daniel J L MacGowan Janine Kirby Erik P Pioro Roger Pamphlett James Broach Glenn Gerhard Travis L Dunckley Christopher B Brady Neil W Kowall Juan C Troncoso Isabelle Le Ber Kevin Mouzat Serge Lumbroso Terry D Heiman-Patterson Freya Kamel Ludo Van Den Bosch Robert H Baloh Tim M Strom Thomas Meitinger Aleksey Shatunov Kristel R Van Eijk Mamede de Carvalho Maarten Kooyman Bas Middelkoop Matthieu Moisse Russell L McLaughlin Michael A Van Es Markus Weber Kevin B Boylan Marka Van Blitterswijk Rosa Rademakers Karen E Morrison A Nazli Basak Jesús S Mora Vivian E Drory Pamela J Shaw Martin R Turner Kevin Talbot Orla Hardiman Kelly L Williams Jennifer A Fifita Garth A Nicholson Ian P Blair Guy A Rouleau Jesús Esteban-Pérez Alberto García-Redondo Ammar Al-Chalabi Ekaterina Rogaeva Lorne Zinman Lyle W Ostrow Nicholas J Maragakis Jeffrey D Rothstein Zachary Simmons Johnathan Cooper-Knock Alexis Brice Stephen A Goutman Eva L Feldman Summer B Gibson Franco Taroni Antonia Ratti Cinzia Gellera Philip Van Damme Wim Robberecht Pietro Fratta Mario Sabatelli Christian Lunetta Albert C Ludolph Peter M Andersen Jochen H Weishaupt William Camu John Q Trojanowski Vivianna M Van Deerlin Robert H Brown Leonard H van den Berg Jan H Veldink Matthew B Harms Jonathan D Glass David J Stone Pentti Tienari Vincenzo Silani Adriano Chiò Christopher E Shaw Bryan J Traynor John E Landers

Neuron 2018 03;97(6):1268-1283.e6

Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01605, USA. Electronic address:

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March 2018

Biomarkers in Neurodegenerative Diseases.

Adv Neurobiol 2017 ;15:491-528

Iron Horse Diagnostics, Inc., Scottsdale, AZ, 85255, USA.

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November 2018

Abnormal expression of homeobox genes and transthyretin in expansion carriers.

Neurol Genet 2017 Aug 7;3(4):e161. Epub 2017 Jun 7.

Department of Neuroscience (N.A.F., M.C.B., T.F.G., K.F.B., M.D.-H., P.H.B., J.C., K.R.J.-W., L.M.D., A.M.N., M.E.M., L.P., D.W.D., R.R., M.v.B.), Department of Health Sciences Research (X.W., Y.W.A.), Department of Neurology (N.R.G.-R., K.B.B.), Division of Biomedical Statistics and Informatics (M.G.H.), Mayo Clinic, Jacksonville, FL; Department of Neurology (J.W., M.B.), University of Miami, FL; Department of Neurology (K.A.J., J.E.P., D.S.K., R.C.P., B.F.B.), Mayo Clinic, Rochester, MN; and Divisions of Neurology and Neurobiology (R.B.), Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ.

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August 2017

Poly(GP) proteins are a useful pharmacodynamic marker for -associated amyotrophic lateral sclerosis.

Sci Transl Med 2017 03;9(383)

Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.

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March 2017

Optical barcoding of PLGA for multispectral analysis of nanoparticle fate in vivo.

J Control Release 2017 05 3;253:172-182. Epub 2017 Mar 3.

Barrow Brain Tumor Research Center, Barrow Neurological Institute, 350 W Thomas Road, Phoenix, AZ 85013, USA; School of Biological and Health Systems Engineering, Arizona State University, P.O. Box 879709, Tempe, AZ 85287, USA. Electronic address:

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May 2017

Fluid-Based Biomarkers for Amyotrophic Lateral Sclerosis.

Neurotherapeutics 2017 01;14(1):119-134

Department of Neurology, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, 350 West Thomas Road, Phoenix, AZ, 85013, USA.

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January 2017

Expression of Carbonic Anhydrase I in Motor Neurons and Alterations in ALS.

Int J Mol Sci 2016 Nov 1;17(11). Epub 2016 Nov 1.

Department of Biological Sciences, Xi'an Jiaotong-Liverpool University, Suzhou 215123, China.

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November 2016

Immunoprecipitation and mass spectrometry defines an extensive RBM45 protein-protein interaction network.

Brain Res 2016 09 12;1647:79-93. Epub 2016 Mar 12.

Divisions of Neurology and Neurobiology, Barrow Neurological Institute, St. Joseph׳s Hospital and Medical Center, Phoenix, AZ 85013, USA; University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA. Electronic address:

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September 2016

Attenuated traumatic axonal injury and improved functional outcome after traumatic brain injury in mice lacking Sarm1.

Brain 2016 Apr 11;139(Pt 4):1094-105. Epub 2016 Feb 11.

1 Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01655, USA.

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April 2016

Reply.

Ann Neurol 2016 Feb 19;79(2):334. Epub 2016 Jan 19.

Department of Neurology, University of Miami, Miami, FL.

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February 2016

Sustainability in a Hospital-Based Biobank and University-Based DNA Biorepository: Strategic Roadmaps.

Biopreserv Biobank 2015 Dec;13(6):401-9

3 DNASU Plasmid Repository, Virginia G. Piper Center for Personalized Diagnostics, Biodesign Institute, Arizona State University , Tempe, Arizona.

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December 2015

Label-Free LC-MS/MS Proteomic Analysis of Cerebrospinal Fluid Identifies Protein/Pathway Alterations and Candidate Biomarkers for Amyotrophic Lateral Sclerosis.

J Proteome Res 2015 Nov 8;14(11):4486-501. Epub 2015 Oct 8.

Departments of Neurology and Neurobiology, Barrow Neurological Institute , NRC427, 350 West Thomas Road, Phoenix, Arizona 85013, United States.

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November 2015

RBM45 homo-oligomerization mediates association with ALS-linked proteins and stress granules.

Sci Rep 2015 Sep 22;5:14262. Epub 2015 Sep 22.

Divisions of Neurology and Neurobiology, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona 85013, USA.

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September 2015

To travel or not to travel: The modern day struggle of the academic researcher.

Ann Neurol 2015 Nov 18;78(5):667-9. Epub 2015 Sep 18.

Department of Neurology, University of Miami, Miller School of Medicine, Miami, FL.

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November 2015

Amyotrophic lateral sclerosis: Is the spinal fluid pathway involved in seeding and spread?

Med Hypotheses 2015 Nov 20;85(5):576-83. Epub 2015 Jul 20.

Barrow Neurological Institute, Gregory W. Fulton ALS and Neuromuscular Research Center, 350 West Thomas Rd., Phoenix, AZ 85013, United States.

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November 2015

Total protein is an effective loading control for cerebrospinal fluid western blots.

J Neurosci Methods 2015 Aug 22;251:72-82. Epub 2015 May 22.

Departments of Neurobiology and Neurology, St. Joseph's Hospital and Medical Center and Barrow Neurological Institute, 350 West Thomas Road, Phoenix, AZ 85013, USA. Electronic address:

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August 2015

Letter to the editor on "Exposure to hazardous air pollutants and the risk of amyotrophic lateral sclerosis".

Environ Pollut 2015 Dec 19;207:432-3. Epub 2015 May 19.

Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA. Electronic address:

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December 2015

RBM45 Modulates the Antioxidant Response in Amyotrophic Lateral Sclerosis through Interactions with KEAP1.

Mol Cell Biol 2015 Jul 4;35(14):2385-99. Epub 2015 May 4.

Divisions of Neurology and Neurobiology, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA

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July 2015

Exposure to hazardous air pollutants and the risk of amyotrophic lateral sclerosis.

Environ Pollut 2015 Feb 23;197:181-186. Epub 2014 Dec 23.

Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, 15261, USA. Electronic address:

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February 2015

Use of biomarkers in ALS drug development and clinical trials.

Brain Res 2015 May 24;1607:94-107. Epub 2014 Oct 24.

Divisions of Neurology and Neurobiology, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ 85013, USA. Electronic address:

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May 2015

Biomarker time out.

Mult Scler 2014 Oct 20;20(12):1560-3. Epub 2014 Feb 20.

Department of Neurology, MS Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands.

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October 2014

Environmental and occupational risk factors for amyotrophic lateral sclerosis: a case-control study.

Neurodegener Dis 2014 12;14(1):31-8. Epub 2013 Nov 12.

Department of Neurosciences, College of Medicine, Medical University of South Carolina, Charleston, S.C., USA.

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February 2015

Therapeutic neuroprotective agents for amyotrophic lateral sclerosis.

Cell Mol Life Sci 2013 Dec 18;70(24):4729-45. Epub 2013 Jul 18.

Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.

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December 2013

Post-lumbar puncture headache is reduced with use of atraumatic needles in ALS.

Amyotroph Lateral Scler Frontotemporal Degener 2013 Dec 8;14(7-8):632-4. Epub 2013 Jul 8.

Department of Neurology, University of Massachusetts, Memorial Medical Center , Worcester, Massachusetts.

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December 2013

Genetic variation in ESR2 and estrogen receptor-beta expression in lung tumors.

Cancer Epidemiol 2013 Aug 23;37(4):518-22. Epub 2013 Apr 23.

Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh and University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA.

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August 2013

Measurement of cystatin C functional activity in the cerebrospinal fluid of amyotrophic lateral sclerosis and control subjects.

Fluids Barriers CNS 2013 Mar 15;10(1):15. Epub 2013 Mar 15.

Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

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March 2013

Reactive astrocytes secrete lcn2 to promote neuron death.

Proc Natl Acad Sci U S A 2013 Mar 19;110(10):4069-74. Epub 2013 Feb 19.

Department of Pathology, Anatomy, and Cell Biology, Thomas Jefferson University, Philadelphia, PA 19107, USA.

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March 2013

Retinoid signaling alterations in amyotrophic lateral sclerosis.

Am J Neurodegener Dis 2012 23;1(2):130-45. Epub 2012 Jul 23.

Department of Pathology, University of Pittsburgh School of Medicine 200 Lothrop Street, Pittsburgh, PA USA.

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February 2013

pNfH is a promising biomarker for ALS.

Amyotroph Lateral Scler Frontotemporal Degener 2013 Mar 22;14(2):146-9. Epub 2012 Oct 22.

King's Health Partners Centre for Neurodegeneration Research, Institute of Psychiatry, Kings College London, UK.

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March 2013

Pesticide exposure as a risk factor for amyotrophic lateral sclerosis: a meta-analysis of epidemiological studies: pesticide exposure as a risk factor for ALS.

Environ Res 2012 Aug 20;117:112-9. Epub 2012 Jul 20.

Department of Neurosciences, College of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.

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August 2012

Neuroprotection for amyotrophic lateral sclerosis: role of stem cells, growth factors, and gene therapy.

Cent Nerv Syst Agents Med Chem 2012 Mar;12(1):15-27

Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Department of Neurosurgery, Boston, Massachusetts 02115, USA.

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March 2012

Survival outcomes in endometrial cancer patients are associated with CXCL12 and estrogen receptor expression.

Int J Cancer 2012 Jul 3;131(2):E114-21. Epub 2012 Jan 3.

Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852-7234, USA.

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July 2012

Biomarkers in amyotrophic lateral sclerosis: opportunities and limitations.

Nat Rev Neurol 2011 Oct 11;7(11):631-8. Epub 2011 Oct 11.

Division of Neurology, Barrow Neurological Institute, St Joseph's Hospital and Medical Center, 350 West Thomas Street, Phoenix, AZ 85213, USA.

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October 2011

Comparison of survival outcomes between patients with malignant mixed mullerian tumors and high-grade endometrioid, clear cell, and papillary serous endometrial cancers.

Int J Gynecol Cancer 2011 Jul;21(5):877-84

Division of Cancer Prevention and Population Science, University of Pittsburgh Cancer Institute, Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, and Department of Obstetrics and Gynecologic Oncology, Magee-Women's Hospital of UPMC Health System, Pittsburgh, PA 15232, USA.

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July 2011

Combination of neurofilament heavy chain and complement C3 as CSF biomarkers for ALS.

J Neurochem 2011 May 21;117(3):528-37. Epub 2011 Mar 21.

Department of Clinical Neuroscience, King's College London, King's Health Partners, MRC Centre for Neurodegeneration Research, London, UK.

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May 2011

Carbonic anhydrase I is recognized by an SOD1 antibody upon biotinylation of human spinal cord extracts.

Int J Mol Sci 2010 Oct 20;11(10):4051-62. Epub 2010 Oct 20.

Department of Neuroscience, California Pacific Medical Center Research Institute, 475 Brannan Street, San Francisco, CA 94107, USA; E-Mail: (M.L.).

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October 2010

Cystatin C: a candidate biomarker for amyotrophic lateral sclerosis.

PLoS One 2010 Dec 9;5(12):e15133. Epub 2010 Dec 9.

Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.

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December 2010

Proposed BioRepository platform solution for the ALS research community.

Amyotroph Lateral Scler 2011 Jan 6;12(1):11-6. Epub 2010 Dec 6.

Neurology Clinical Trials Unit, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA.

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January 2011

A pilot trial of memantine and riluzole in ALS: correlation to CSF biomarkers.

Amyotroph Lateral Scler 2010 Dec 14;11(6):514-9. Epub 2010 Sep 14.

PNA Center for Neurologic Research, 5090 N 40th St., Phoenix, AZ 85018, USA.

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December 2010

Factors associated with Type I and Type II endometrial cancer.

Cancer Causes Control 2010 Nov 14;21(11):1851-6. Epub 2010 Jul 14.

Division of Cancer Prevention and Population Science, University of Pittsburgh Cancer Institute, 5150 Centre Avenue, Suite 4-C, Pittsburgh, PA 15232, USA.

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November 2010

Discovery and verification of amyotrophic lateral sclerosis biomarkers by proteomics.

Muscle Nerve 2010 Jul;42(1):104-11

Department of Pathology, University of Pittsburgh School of Medicine, BST S-420, 200 Lothrop Street, Pittsburgh, Pennsylvania 15261, USA.

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July 2010

The application of biomarkers in clinical trials for motor neuron disease.

Biomark Med 2010 Apr;4(2):281-97

Department of Clinical Neurosciences, Institute of Psychiatry, Kings College London, UK.

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April 2010

Transgenic rat model of neurodegeneration caused by mutation in the TDP gene.

PLoS Genet 2010 Mar 26;6(3):e1000887. Epub 2010 Mar 26.

Department of Pathology, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America.

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March 2010

p53 and Cell Cycle Proteins Participate in Spinal Motor Neuron Cell Death in ALS.

Open Pathol J 2010 Jan;4:11-22

Department of Pathology, Pittsburgh, PA, USA.

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January 2010

Knowledge-based variable selection for learning rules from proteomic data.

BMC Bioinformatics 2009 Sep 17;10 Suppl 9:S16. Epub 2009 Sep 17.

Department of Biomedical Informatics, University of Pittsburgh, 200 Meyran Ave, Parkvale M-183, Pittsburgh, PA, USA.

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September 2009

Applying proteomics to the diagnosis and treatment of ALS and related diseases.

Muscle Nerve 2009 Nov;40(5):753-62

Department of Pathology, University of Pittsburgh School of Medicine, BST S-420, 200 Lothrop Street, Pittsburgh, Pennsylvania 15261, USA.

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November 2009

Altered subcellular distribution of c-Abl in Alzheimer's disease.

J Alzheimers Dis 2009 ;17(2):409-22

Department of Pathology, University of Pittsburgh, School of Medicine, BST S-420, 200 Lothrop Street, Pittsburgh, PA 15261, USA.

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December 2009

Using a novel resource to decrease proteomic biomarker identification time.

AMIA Annu Symp Proc 2008 Nov 6:1033. Epub 2008 Nov 6.

Department of Biomedical Informatics, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.

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November 2008

Protein biomarkers for amyotrophic lateral sclerosis.

Expert Rev Proteomics 2008 Apr;5(2):249-62

Department of Pathology, Center for ALS Research, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.

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April 2008

Comparative proteomic profiling of cerebrospinal fluid between living and post mortem ALS and control subjects.

Amyotroph Lateral Scler 2007 Dec 3;8(6):373-9. Epub 2007 Aug 3.

Neurogenetics Branch, National Institute of Neurological Disorders and Stroke, National Institute of Health, Bethesda, MD, USA.

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December 2007

Common molecular signature in SOD1 for both sporadic and familial amyotrophic lateral sclerosis.

Proc Natl Acad Sci U S A 2007 Jul 16;104(30):12524-9. Epub 2007 Jul 16.

Bioconformatics Laboratory and Department of Neuroscience, California Pacific Medical Center Research Institute, San Francisco, CA 94107, USA.

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July 2007

Focal adhesions regulate Abeta signaling and cell death in Alzheimer's disease.

Biochim Biophys Acta 2007 Apr 30;1772(4):438-45. Epub 2006 Nov 30.

Department of Pathology, University of Pittsburgh School of Medicine, BST S-420, 200 Lothrop St., Pittsburgh, PA 15261, USA.

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April 2007

Plasma and cerebrospinal fluid-based protein biomarkers for motor neuron disease.

Mol Diagn Ther 2006 ;10(5):281-92

Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA.

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December 2006

Increased expression of p130 in Alzheimer disease.

Neurochem Res 2007 Apr-May;32(4-5):639-44. Epub 2006 Sep 28.

Department of Pathology, Case Western Reserve University, 2103 Cornell Road, Cleveland, OH 44106, USA.

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May 2007

Biomarkers for amyotrophic lateral sclerosis.

Expert Rev Mol Diagn 2006 May;6(3):387-98

University of Pittsburgh, Department of Pathology, School of Medicine, ST S-420, 200 Lothrop Street, Pittsburgh, PA 15261, USA.

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May 2006

Functional repression of cAMP response element in 6-hydroxydopamine-treated neuronal cells.

J Biol Chem 2006 Jun 18;281(26):17870-81. Epub 2006 Apr 18.

Department of Pathology, Division of Neuropathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.

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June 2006

DNA damage induces cdk2 protein levels and histone H2B phosphorylation in SH-SY5Y neuroblastoma cells.

J Alzheimers Dis 2005 Sep;8(1):7-21

Department of Pathology, Division of Neuropathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.

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September 2005

Biomarker World Congress 2005.

Per Med 2005 Aug;2(3):209-212

Knopp NeuroSciences, Inc., 100 Technology Drive, Suite 400, Pittsburgh, PA 15219, USA.

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August 2005

Fetal Alz-50 clone 1 interacts with the human orthologue of the Kelch-like Ech-associated protein.

Biochemistry 2004 Sep;43(38):12113-22

Department of Pathology, University of Pennsylvania, 4010 Locust Street, Philadelphia, Pennsylvania 19104-6030, USA.

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September 2004

Alzheimer disease pathology in amyotrophic lateral sclerosis.

Acta Neuropathol 2004 Jun 16;107(6):515-22. Epub 2004 Mar 16.

A-506, Presbyterian University Hospital, 200 Lothrop Street, Pittsburgh, PA 15213, USA.

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June 2004