Robert Blelloch

Robert Blelloch

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Robert Blelloch

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Epigenetic control of transcriptional regulation in pluripotency and early differentiation.

Development 2019 Sep 25;146(19). Epub 2019 Sep 25.

The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Center for Reproductive Sciences, University of California San Francisco, San Francisco, CA 94143, USA

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http://dx.doi.org/10.1242/dev.164772DOI Listing
September 2019

Suppression of Exosomal PD-L1 Induces Systemic Anti-tumor Immunity and Memory.

Cell 2019 Apr;177(2):414-427.e13

Department of Urology, University of California, San Francisco, San Francisco, CA 94143, USA; Eli and Edith Broad Institute for Regeneration Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.02.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499401PMC
April 2019

High-throughput, Efficient, and Unbiased Capture of Small RNAs from Low-input Samples for Sequencing.

Sci Rep 2019 Feb 19;9(1):2262. Epub 2019 Feb 19.

The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, CA, 94143, USA.

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http://dx.doi.org/10.1038/s41598-018-38458-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381177PMC
February 2019

GRHL2-Dependent Enhancer Switching Maintains a Pluripotent Stem Cell Transcriptional Subnetwork after Exit from Naive Pluripotency.

Cell Stem Cell 2018 Aug 12;23(2):226-238.e4. Epub 2018 Jul 12.

The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Center for Reproductive Sciences, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Urology, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2018.06.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456389PMC
August 2018

Decoupling the impact of microRNAs on translational repression versus RNA degradation in embryonic stem cells.

Elife 2018 07 25;7. Epub 2018 Jul 25.

The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Center for Reproductive Sciences, University of California, San Francisco, San Francisco, United States.

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http://dx.doi.org/10.7554/eLife.38014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086665PMC
July 2018

Expression of Alternative Ago2 Isoform Associated with Loss of microRNA-Driven Translational Repression in Mouse Oocytes.

Curr Biol 2018 01 4;28(2):296-302.e3. Epub 2018 Jan 4.

The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Center for Reproductive Sciences, University of California, San Francisco, 35 Medical Center Way, San Francisco, CA 94143, USA; Department of Urology, University of California, San Francisco, 35 Medical Center Way, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2017.11.067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790201PMC
January 2018

The eutheria-specific miR-290 cluster modulates placental growth and maternal-fetal transport.

Development 2017 10 21;144(20):3731-3743. Epub 2017 Sep 21.

The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Center for Reproductive Sciences, University of California, San Francisco, San Francisco, CA 94143, USA

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http://dev.biologists.org/lookup/doi/10.1242/dev.151654
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http://dx.doi.org/10.1242/dev.151654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675445PMC
October 2017

NF45 and NF90/NF110 coordinately regulate ESC pluripotency and differentiation.

RNA 2017 08 9;23(8):1270-1284. Epub 2017 May 9.

The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Center for Reproductive Sciences, University of California, San Francisco, San Francisco, California 94143, USA.

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http://dx.doi.org/10.1261/rna.061499.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513071PMC
August 2017

Patterning of sharp cellular interfaces with a reconfigurable elastic substrate.

Integr Biol (Camb) 2017 01;9(1):50-57

Department of Biomedical Engineering, University of California, Irvine, California 92697-2715, USA.

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http://dx.doi.org/10.1039/c6ib00203jDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575999PMC
January 2017

The impact of microRNAs on transcriptional heterogeneity and gene co-expression across single embryonic stem cells.

Nat Commun 2017 01 19;8:14126. Epub 2017 Jan 19.

The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Center for Reproductive Sciences, University of California, San Francisco, San Francisco, California 94143, USA.

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http://dx.doi.org/10.1038/ncomms14126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253645PMC
January 2017

A miR-372/let-7 Axis Regulates Human Germ Versus Somatic Cell Fates.

Stem Cells 2016 07 17;34(7):1985-91. Epub 2016 May 17.

Departments of OB/Gyn and Urology, Center for Reproductive Sciences, and the Eli and Edythe Broad Center for Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, California, USA.

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http://dx.doi.org/10.1002/stem.2378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5145290PMC
July 2016

MicroRNA Regulation of Embryonic Stem Cell Self-Renewal and Differentiation.

Adv Exp Med Biol 2010 ;695:105-17

The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Center for Reproductive Sciences, Biomedical Science Graduate Program and Department of Urology, University of California San Francisco, San Francisco, California, 94143, USA.

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http://dx.doi.org/10.1007/978-1-4419-7037-4_8DOI Listing
April 2016

FOXD3 Regulates Pluripotent Stem Cell Potential by Simultaneously Initiating and Repressing Enhancer Activity.

Cell Stem Cell 2016 Jan;18(1):104-17

The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Center for Reproductive Sciences, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Urology, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2015.10.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4775235PMC
January 2016

Fas-Activated Mitochondrial Apoptosis Culls Stalled Embryonic Stem Cells to Promote Differentiation.

Curr Biol 2015 Dec 12;25(23):3110-8. Epub 2015 Nov 12.

Department of Pathology, University of California, San Francisco, San Francisco, CA 94143, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94143, USA; Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2015.10.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703423PMC
December 2015

DGCR8 is essential for tumor progression following PTEN loss in the prostate.

EMBO Rep 2015 Sep 23;16(9):1219-32. Epub 2015 Jul 23.

The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California - San Francisco, San Francisco, CA, USA Center for Reproductive Sciences, University of California - San Francisco, San Francisco, CA, USA Department of Urology, University of California - San Francisco, San Francisco, CA, USA Department of Anatomic Pathology, University of California - San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.15252/embr.201439925DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576988PMC
September 2015

miR-302 Is Required for Timing of Neural Differentiation, Neural Tube Closure, and Embryonic Viability.

Cell Rep 2015 Aug 23;12(5):760-73. Epub 2015 Jul 23.

The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Center for Reproductive Sciences, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Urology, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.06.074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741278PMC
August 2015

Let-7 and miR-125 cooperate to prime progenitors for astrogliogenesis.

EMBO J 2015 May 23;34(9):1180-94. Epub 2015 Feb 23.

Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Center for Reproductive Sciences and Department of Urology, University of California San Francisco, San Francisco, CA, USA

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http://dx.doi.org/10.15252/embj.201489504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426479PMC
May 2015

CDK1 inhibition targets the p53-NOXA-MCL1 axis, selectively kills embryonic stem cells, and prevents teratoma formation.

Stem Cell Reports 2015 Mar 26;4(3):374-89. Epub 2015 Feb 26.

Department of Cell and Tissue Biology and Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2015.01.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375943PMC
March 2015

Regulation of microRNA function in somatic stem cell proliferation and differentiation.

Nat Rev Mol Cell Biol 2014 Sep 13;15(9):565-76. Epub 2014 Aug 13.

Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Center for Reproductive Sciences and Department of Urology, University of California San Francisco, San Francisco, California CA 94143-0667, USA.

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http://dx.doi.org/10.1038/nrm3854DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377327PMC
September 2014

Regulation of pluripotency by RNA binding proteins.

Cell Stem Cell 2014 Sep;15(3):271-280

The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Center for Reproductive Sciences, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Urology, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2014.08.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372238PMC
September 2014

Two miRNA clusters reveal alternative paths in late-stage reprogramming.

Cell Stem Cell 2014 May 13;14(5):617-31. Epub 2014 Mar 13.

The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Center for Reproductive Sciences, University of California, San Francisco, San Francisco, California, 94143, USA; Department of Urology, University of California, San Francisco, San Francisco, California, 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2014.01.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305531PMC
May 2014

DGCR8-mediated production of canonical microRNAs is critical for regulatory T cell function and stability.

PLoS One 2013 31;8(5):e66282. Epub 2013 May 31.

Diabetes Center and the Department of Medicine, University of California San Francisco, San Francisco, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0066282PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669207PMC
January 2014

microRNA control of mouse and human pluripotent stem cell behavior.

Annu Rev Cell Dev Biol 2013 12;29:213-239. Epub 2013 Jul 12.

Department of Urology and The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Center for Reproductive Sciences, Program in Biomedical Sciences, University of California, San Francisco, California, 94143.

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http://dx.doi.org/10.1146/annurev-cellbio-101512-122343DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793955PMC
December 2013

Epigenetics of cellular reprogramming.

Curr Opin Genet Dev 2013 Oct 12;23(5):548-55. Epub 2013 Aug 12.

Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Center for Reproductive Sciences and Department of Urology, University of California San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1016/j.gde.2013.06.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359361PMC
October 2013

MicroRNA-based discovery of barriers to dedifferentiation of fibroblasts to pluripotent stem cells.

Nat Struct Mol Biol 2013 Oct 15;20(10):1227-35. Epub 2013 Sep 15.

1] The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Center for Reproductive Sciences, Program in Biomedical Sciences, University of California San Francisco, San Francisco, California, USA. [2] Department of Urology, University of California San Francisco, San Francisco, California, USA.

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http://dx.doi.org/10.1038/nsmb.2665DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3955211PMC
October 2013

Small RNAs in germline development.

Curr Top Dev Biol 2013 ;102:159-205

Department of Urology, University of California, San Francisco, California, USA.

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http://dx.doi.org/10.1016/B978-0-12-416024-8.00006-4DOI Listing
September 2013

miR-294/miR-302 promotes proliferation, suppresses G1-S restriction point, and inhibits ESC differentiation through separable mechanisms.

Cell Rep 2013 Jul 3;4(1):99-109. Epub 2013 Jul 3.

Peking-Tsinghua Joint Center for Life Sciences, Institute of Molecular Medicine, Peking University, Beijing 100871, China.

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http://dx.doi.org/10.1016/j.celrep.2013.05.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740202PMC
July 2013

Regulation of epithelial-mesenchymal and mesenchymal-epithelial transitions by microRNAs.

Curr Opin Cell Biol 2013 Apr 20;25(2):200-7. Epub 2013 Feb 20.

Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Department of Cell and Tissue Biology, University of California San Francisco, San Francisco, CA 94143, United States.

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http://dx.doi.org/10.1016/j.ceb.2013.01.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240277PMC
April 2013

Epigenetics, noncoding RNAs, and cell signaling--crossroads in the regulation of cell fate decisions.

Curr Opin Cell Biol 2013 Apr 13;25(2):149-51. Epub 2013 Mar 13.

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http://dx.doi.org/10.1016/j.ceb.2013.02.019DOI Listing
April 2013

Sox1 marks an activated neural stem/progenitor cell in the hippocampus.

Development 2012 Nov 19;139(21):3938-49. Epub 2012 Sep 19.

Department of Urology, University of California, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1242/dev.081133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472585PMC
November 2012

An integrated nano-scale approach to profile miRNAs in limited clinical samples.

Am J Clin Exp Immunol 2012 Nov;1(2):70-89

Sandler Asthma Basic Research Center, University of California San Francisco, San Francisco, CA, USA ; Division of Infection, Inflammation and Immunity, University of outhampton, School of Medicine, Southampton NIHR Respiratory Biomedical Research Unit, Sir Henry Wellcome Laboratories, Southampton General Hospital, Southampton, UK ; Pulmonary and Critical Care Division, Department of Medicine, University of California San Francisco.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538381PMC
November 2012

microRNA induced transdifferentiation.

F1000 Biol Rep 2012 1;4. Epub 2012 Feb 1.

The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Center for Reproductive Sciences Department of Urology, 35 Medical Center Way, Pod B 1018, University of California, San Francisco, San Francisco, CA. 94143 - 0667 USA.

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http://www.f1000.com/reports/b/4/3/
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http://dx.doi.org/10.3410/B4-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270586PMC
October 2012

Generation of induced pluripotent stem cells from the prairie vole.

PLoS One 2012 31;7(5):e38119. Epub 2012 May 31.

Department of Anatomy, University of California San Francisco, San Francisco, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0038119PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365000PMC
September 2012

Efficiency and specificity in microRNA biogenesis.

Nat Struct Mol Biol 2012 May 13;19(6):650-2. Epub 2012 May 13.

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.

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http://dx.doi.org/10.1038/nsmb.2293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378260PMC
May 2012

Dgcr8 controls neural crest cells survival in cardiovascular development.

Dev Biol 2012 Feb 23;362(1):50-6. Epub 2011 Nov 23.

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.

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https://linkinghub.elsevier.com/retrieve/pii/S00121606110137
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http://dx.doi.org/10.1016/j.ydbio.2011.11.008DOI Listing
February 2012

Cell cycle regulation by microRNAs in stem cells.

Results Probl Cell Differ 2011 ;53:459-72

The Institute of Molecular Medicine, Peking University, Beijing, China.

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http://dx.doi.org/10.1007/978-3-642-19065-0_19DOI Listing
August 2011

From microRNAs to targets: pathway discovery in cell fate transitions.

Curr Opin Genet Dev 2011 Aug 1;21(4):498-503. Epub 2011 Jun 1.

Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Center for Reproductive Sciences, Department of Urology, University of California San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1016/j.gde.2011.04.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210035PMC
August 2011

A role for noncanonical microRNAs in the mammalian brain revealed by phenotypic differences in Dgcr8 versus Dicer1 knockouts and small RNA sequencing.

RNA 2011 Aug 28;17(8):1489-501. Epub 2011 Jun 28.

The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Center for Reproductive Sciences, University of California, San Francisco, San Francisco, California 94143, USA.

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http://dx.doi.org/10.1261/rna.2442211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153973PMC
August 2011

MicroRNA-29 regulates T-box transcription factors and interferon-γ production in helper T cells.

Immunity 2011 Aug 4;35(2):169-81. Epub 2011 Aug 4.

Sandler Asthma Basic Research Center and Department of Microbiology & Immunology, University of California, San Francisco, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1016/j.immuni.2011.07.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3361370PMC
August 2011

High throughput microRNA profiling: optimized multiplex qRT-PCR at nanoliter scale on the fluidigm dynamic arrayTM IFCs.

J Vis Exp 2011 Aug 3(54). Epub 2011 Aug 3.

The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, USA.

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http://dx.doi.org/10.3791/2552DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3211115PMC
August 2011

Small RNAs in early mammalian development: from gametes to gastrulation.

Development 2011 May;138(9):1653-61

The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Center for Reproductive Sciences, and Department of Urology, University of California San Francisco, San Francisco, CA 94143, USA.

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http://dev.biologists.org/cgi/doi/10.1242/dev.056234
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http://dx.doi.org/10.1242/dev.056234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074443PMC
May 2011

Multiple targets of miR-302 and miR-372 promote reprogramming of human fibroblasts to induced pluripotent stem cells.

Nat Biotechnol 2011 May 13;29(5):443-8. Epub 2011 Apr 13.

Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, California, USA.

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http://www.nature.com/articles/nbt.1862
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http://dx.doi.org/10.1038/nbt.1862DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685579PMC
May 2011

Microfluidic-based multiplex qRT-PCR identifies diagnostic and prognostic microRNA signatures in the sera of prostate cancer patients.

Cancer Res 2011 Jan 22;71(2):550-60. Epub 2010 Nov 22.

The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Department of Urology, UCSF-Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California 94143, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-1229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022112PMC
January 2011

PML-RAR{alpha} and Dnmt3a1 cooperate in vivo to promote acute promyelocytic leukemia.

Cancer Res 2010 Nov 21;70(21):8792-801. Epub 2010 Sep 21.

Institute for Regeneration Medicine, University of California, San Francisco, California 94143, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-4481DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3021794PMC
November 2010

Distinct requirements of microRNAs in NK cell activation, survival, and function.

J Immunol 2010 Oct 30;185(7):3835-46. Epub 2010 Aug 30.

Department of Microbiology and Immunology, Cancer Research Institute, University of California San Francisco, San Francisco, CA 94143, USA.

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http://www.jimmunol.org/content/185/7/3835.full.pdf
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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1000980
Publisher Site
http://dx.doi.org/10.4049/jimmunol.1000980DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943981PMC
October 2010

On the streets of San Francisco: highlights from the ISSCR Annual Meeting 2010.

Cell Stem Cell 2010 Oct;7(4):443-50

Monash Immunology and Stem Cell Laboratories, Monash University, Clayton, Victoria, 3800, Australia.

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http://dx.doi.org/10.1016/j.stem.2010.09.002DOI Listing
October 2010

MicroRNAs control hepatocyte proliferation during liver regeneration.

Hepatology 2010 May;51(5):1735-43

Eli and Edythe Broad Center for Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1002/hep.23547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108060PMC
May 2010

Opposing microRNA families regulate self-renewal in mouse embryonic stem cells.

Nature 2010 Feb 6;463(7281):621-6. Epub 2010 Jan 6.

The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Center for Reproductive Sciences, Program in Biomedical Sciences, University of California San Francisco, San Francisco, California 94143, USA.

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http://dx.doi.org/10.1038/nature08725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894702PMC
February 2010

MicroRNA function is globally suppressed in mouse oocytes and early embryos.

Curr Biol 2010 Feb 28;20(3):271-7. Epub 2010 Jan 28.

The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1016/j.cub.2009.12.044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872512PMC
February 2010

Watching reprogramming in real time.

Nat Biotechnol 2009 Nov;27(11):997-8

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http://dx.doi.org/10.1038/nbt1109-997DOI Listing
November 2009

Journal club. A computational biologist looks at how mRNA length changes during development.

Authors:
Robert Blelloch

Nature 2009 Nov;462(7270):141

University of California, San Francisco, USA.

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http://dx.doi.org/10.1038/462141eDOI Listing
November 2009

Genomic analysis suggests that mRNA destabilization by the microprocessor is specialized for the auto-regulation of Dgcr8.

PLoS One 2009 Sep 11;4(9):e6971. Epub 2009 Sep 11.

The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Center for Reproductive Sciences, and Department of Urology, University of California San Francisco, San Francisco, CA, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0006971PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736397PMC
September 2009

Embryonic stem cell-specific microRNAs promote induced pluripotency.

Nat Biotechnol 2009 May 12;27(5):459-61. Epub 2009 Apr 12.

The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, California, USA.

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http://dx.doi.org/10.1038/nbt.1535DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2743930PMC
May 2009

Cell cycle regulation by MicroRNAs in embryonic stem cells.

Cancer Res 2009 May 12;69(10):4093-6. Epub 2009 May 12.

The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-0309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894693PMC
May 2009

Posttranscriptional crossregulation between Drosha and DGCR8.

Cell 2009 Jan;136(1):75-84

School of Biological Sciences and National Creative Research Center, Seoul National University, Seoul 151-742, Korea.

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http://dx.doi.org/10.1016/j.cell.2008.10.053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680683PMC
January 2009

Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation.

Nat Genet 2008 Dec 2;40(12):1478-83. Epub 2008 Nov 2.

Institute for Regeneration Medicine, Center for Reproductive Sciences and Department of Urology, University of California San Francisco, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1038/ng.250DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630798PMC
December 2008

Regenerative medicine: short cut to cell replacement.

Authors:
Robert Blelloch

Nature 2008 Oct;455(7213):604-5

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October 2008

Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicer-dependent small RNAs.

Genes Dev 2008 Oct;22(20):2773-85

Institute for Regeneration Medicine, Center for Reproductive Sciences, University of California at San Francisco, San Francisco, California 94143, USA.

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http://dx.doi.org/10.1101/gad.1705308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2569885PMC
October 2008

CompMoby: comparative MobyDick for detection of cis-regulatory motifs.

BMC Bioinformatics 2008 Oct 27;9:455. Epub 2008 Oct 27.

Department of Biochemistry and Biophysics, California Institute for Quantitative Biomedical Research, Graduate Program in Biological and Medical Informatics, University of California, San Francisco, CA 94143-2540, USA.

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http://dx.doi.org/10.1186/1471-2105-9-455DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605473PMC
October 2008

DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal.

Nat Genet 2007 Mar 28;39(3):380-5. Epub 2007 Jan 28.

Developmental and Stem Cell Biology Program, Department of Urology, University of California, San Francisco, California 94143, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008549PMC
March 2007

Reprogramming efficiency following somatic cell nuclear transfer is influenced by the differentiation and methylation state of the donor nucleus.

Stem Cells 2006 Sep 18;24(9):2007-13. Epub 2006 May 18.

Whitehead Instituteand Department of Biology, Massachusetts Institute of Technology, Cambridge, USA.

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http://dx.doi.org/10.1634/stemcells.2006-0050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000431PMC
September 2006

TRA-1/GLI controls development of somatic gonadal precursors in C. elegans.

Development 2004 Sep 4;131(17):4333-43. Epub 2004 Aug 4.

Department of Biochemistry and Howard Hughes Medical Institute, University of Wisconsin-Madison, Madison, WI 53706-1544, USA.

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http://dx.doi.org/10.1242/dev.01288DOI Listing
September 2004

Nuclear cloning of embryonal carcinoma cells.

Proc Natl Acad Sci U S A 2004 Sep 11;101(39):13985-90. Epub 2004 Aug 11.

Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA.

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http://dx.doi.org/10.1073/pnas.0405015101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC521109PMC
September 2004

Reprogramming of a melanoma genome by nuclear transplantation.

Genes Dev 2004 Aug;18(15):1875-85

Whitehead Institute for Biomedical Research, and Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC517407PMC
August 2004