Publications by authors named "Robert Bals"

100Publications

Genetic insight into COVID-19 related liver injury: a note on MBOAT7.

Liver Int 2020 Nov 17. Epub 2020 Nov 17.

Department of Medicine II, Saarland University Medical Center, Saarland University, Homburg, Germany.

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http://dx.doi.org/10.1111/liv.14732DOI Listing
November 2020

The Distribution of Alpha-1 Antitrypsin Genotypes Between Patients with COPD/Emphysema, Asthma and Bronchiectasis.

Int J Chron Obstruct Pulmon Dis 2020 6;15:2827-2836. Epub 2020 Nov 6.

Department of Medicine, Pulmonary and Critical Care Medicine, University Medical Center Giessen and Marburg, Member of the German Center for Lung Research, Marburg, Germany.

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http://dx.doi.org/10.2147/COPD.S271810DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7654539PMC
November 2020

Impact of Education on COPD Severity and All-Cause Mortality in Lifetime Never-Smokers and Longtime Ex-Smokers: Results of the COSYCONET Cohort.

Int J Chron Obstruct Pulmon Dis 2020 5;15:2787-2798. Epub 2020 Nov 5.

Department of Internal Medicine V, University of Munich (LMU), Comprehensive Pneumology Center, Member of the German Center for Lung Research (DZL), Munich, 80336, Germany.

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http://dx.doi.org/10.2147/COPD.S273839DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652228PMC
November 2020

Management of lung transplantation in the COVID-19 era-An international survey.

Am J Transplant 2020 Oct 21. Epub 2020 Oct 21.

Department of Internal Medicine V - Pneumology, Allergology and Intensive Care Medicine, Saarland University Medical Center, Homburg, Germany.

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http://dx.doi.org/10.1111/ajt.16368DOI Listing
October 2020

Micro-rheological properties of lung homogenates correlate with infection severity in a mouse model of Pseudomonas aeruginosa lung infection.

Sci Rep 2020 10 5;10(1):16502. Epub 2020 Oct 5.

Department of Drug Design and Optimization (DDOP), Helmholtz-Institute for Pharmaceutical Research Saarland (HIPS)-Helmholtz Centre for Infection Research (HZI), Campus E8.1, 66123, Saarbrücken, Germany.

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http://dx.doi.org/10.1038/s41598-020-73459-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7536435PMC
October 2020

A mock circulation loop to test extracorporeal CO elimination setups.

Intensive Care Med Exp 2020 Dec 11;8:52. Epub 2020 Sep 11.

Department of Internal Medicine V - Pneumology and Intensive Care Medicine, University Hospital of Saarland, Kirrbergerstr. 1, 66421 Homburg, Germany.

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http://dx.doi.org/10.1186/s40635-020-00341-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484925PMC
December 2020

Gastrointestinal endoscopy during extracorporeal membrane oxygenation (ECMO) for COVID-19.

J Gastrointestin Liver Dis 2020 Sep 9;29(3):471-473. Epub 2020 Sep 9.

Department of Medicine II: Gastroenterology, Hepatology and Endocrinology, Saarland University Medical Center, Saarland University, Homburg, Germany.

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http://dx.doi.org/10.15403/jgld-2826DOI Listing
September 2020

A mock circulation loop to test extracorporeal CO elimination setups.

Intensive Care Med Exp 2020 Sep 11;8(1):52. Epub 2020 Sep 11.

Department of Internal Medicine V - Pneumology and Intensive Care Medicine, University Hospital of Saarland, Kirrbergerstr. 1, 66421, Homburg, Germany.

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http://dx.doi.org/10.1186/s40635-020-00341-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484925PMC
September 2020

Flagellin shifts 3D bronchospheres towards mucus hyperproduction.

Respir Res 2020 Aug 26;21(1):222. Epub 2020 Aug 26.

Department of Internal Medicine V - Pulmonology, Allergology and Respiratory Critical Care Medicine, Saarland University, Kirrberger Str. 100, Building 41M, 66421, Homburg/Saar, Germany.

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http://dx.doi.org/10.1186/s12931-020-01486-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448433PMC
August 2020

Prediction of air trapping or pulmonary hyperinflation by forced spirometry in COPD patients: results from COSYCONET.

ERJ Open Res 2020 Jul 27;6(3). Epub 2020 Jul 27.

Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, University Hospital, LMU Munich, Comprehensive Pneumology Center Munich (CPC-M), member of the DZL, Munich, Germany.

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http://dx.doi.org/10.1183/23120541.00092-2020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383055PMC
July 2020

The effects of a short-term physician training on smoking cessation in a university pulmonary department.

Ger Med Sci 2020 3;18:Doc06. Epub 2020 Jul 3.

Department of Internal Medicine V - Pulmonology, Allergology and Critical Care Medicine, Saarland University, Homburg, Germany.

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http://dx.doi.org/10.3205/000282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373096PMC
July 2020

Blood glucose, diabetes and metabolic control in patients with community-acquired pneumonia.

Diabetologia 2020 11 17;63(11):2488-2490. Epub 2020 Jul 17.

Nestlé Health Science, Vevey, Switzerland.

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http://dx.doi.org/10.1007/s00125-020-05225-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366469PMC
November 2020

The IL-17 receptor IL-17RE mediates polyIC-induced exacerbation of experimental allergic asthma.

Respir Res 2020 Jul 8;21(1):176. Epub 2020 Jul 8.

Department of Internal Medicine V - Pulmonology, Allergology and Critical Care Medicine, Saarland University, D-66421, Homburg, Germany.

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http://dx.doi.org/10.1186/s12931-020-01434-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346407PMC
July 2020

P. aeruginosa Infected 3D Co-Culture of Bronchial Epithelial Cells and Macrophages at Air-Liquid Interface for Preclinical Evaluation of Anti-Infectives.

J Vis Exp 2020 06 15(160). Epub 2020 Jun 15.

Department of Drug Delivery, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS); Department of Pharmacy, Saarland University;

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http://dx.doi.org/10.3791/61069DOI Listing
June 2020

Easy measurement of health related quality of life in patients with cystic fibrosis by the COPD assessment test (CAT) - A pilot study.

Respir Med 2020 07 30;168:105992. Epub 2020 Apr 30.

Department of Internal Medicine V - Pulmonology, Allergology, Critical Care Medicine, Saarland University Hospital, Homburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.rmed.2020.105992DOI Listing
July 2020

Liver Phenotypes of European Adults Heterozygous or Homozygous for Pi∗Z Variant of AAT (Pi∗MZ vs Pi∗ZZ genotype) and Noncarriers.

Gastroenterology 2020 Aug 4;159(2):534-548.e11. Epub 2020 May 4.

Medical Clinic III, Gastroenterology, Metabolic diseases and Intensive Care, University Hospital RWTH Aachen, Aachen, Germany; Coordinating Center for alpha-1 antitrypsin deficiency-related liver disease of the European Reference Network (ERN) "Rare Liver" and the European Association for the Study of the Liver (EASL) registry group "Alpha-1 Liver," University Hospital Aachen, Aachen, Germany. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2020.04.058DOI Listing
August 2020

Cigarette smoke and electronic cigarettes differentially activate bronchial epithelial cells.

Respir Res 2020 Mar 12;21(1):67. Epub 2020 Mar 12.

Department of Internal Medicine V - Pulmonology, Allergology and Critical Care Medicine, Saarland University, D-66421, Homburg, Germany.

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http://dx.doi.org/10.1186/s12931-020-1317-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068890PMC
March 2020

Exposure of patients to di(2-ethylhexy)phthalate (DEHP) and its metabolite MEHP during extracorporeal membrane oxygenation (ECMO) therapy.

PLoS One 2020 30;15(1):e0224931. Epub 2020 Jan 30.

Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0224931PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992201PMC
March 2020

Diagnosing Alpha-1-Antitrypsin Deficiency Using A PCR/Luminescence-Based Technology.

Int J Chron Obstruct Pulmon Dis 2019 18;14:2535-2542. Epub 2019 Nov 18.

Department of Medicine, Pulmonary and Critical Care Medicine, Member of the German Center for Lung Research Marburg, University Medical Center Giessen And Marburg, Germany.

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http://dx.doi.org/10.2147/COPD.S224221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873957PMC
April 2020

CAT score single item analysis in patients with COPD: Results from COSYCONET.

Respir Med 2019 11 7;159:105810. Epub 2019 Nov 7.

Department of Internal Medicine V, University of Munich (LMU), Comprehensive Pneumology Center, Member of the German Center for Lung Research, Ziemssenstr. 1, 80336, Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.rmed.2019.105810DOI Listing
November 2019

Time-updated resting heart rate predicts mortality in patients with COPD.

Clin Res Cardiol 2020 Jun 16;109(6):776-786. Epub 2019 Nov 16.

Department of Internal Medicine V - Pulmonology, Allergology, Critical Care Medicine, Saarland University Medical Centre, Saarland University Hospital, 66421, Homburg/Saar, Germany.

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http://dx.doi.org/10.1007/s00392-019-01572-1DOI Listing
June 2020

The Phagocytosis of Blood Leukocytes from Cystic Fibrosis Patients is not Impaired in General.

Lung 2020 02 9;198(1):235-239. Epub 2019 Nov 9.

Institute for Anatomy and Cell Biology, Saarland University, Campus Homburg, Kirrberger Strasse, Building 61, 66424, Homburg/Saar, Germany.

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http://dx.doi.org/10.1007/s00408-019-00290-9DOI Listing
February 2020

Adherence To Respiratory And Nonrespiratory Medication In Patients With COPD: Results Of The German COSYCONET Cohort.

Patient Prefer Adherence 2019 10;13:1711-1721. Epub 2019 Oct 10.

Department of Internal Medicine V, University of Munich, Comprehensive Pneumology Center, Member of the German Center for Lung Research, Munich 80336, Germany.

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http://dx.doi.org/10.2147/PPA.S223438DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791408PMC
October 2019

Prevalence of cardiac comorbidities, and their underdetection and contribution to exertional symptoms in COPD: results from the COSYCONET cohort.

Int J Chron Obstruct Pulmon Dis 2019 20;14:2163-2172. Epub 2019 Sep 20.

Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, University Hospital, LMU Munich, Comprehensive Pneumology Center Munich (CPC-M), Member of the Center for Lung Research (DZL), Munich, Germany.

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http://dx.doi.org/10.2147/COPD.S209343DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759215PMC
April 2020

Interleukin 17 Receptor E (IL-17RE) and IL-17C Mediate the Recruitment of Neutrophils during Acute Pneumonia.

Infect Immun 2019 11 18;87(11). Epub 2019 Oct 18.

Department of Internal Medicine V-Pulmonology, Allergology and Critical Care Medicine, Saarland University, Homburg, Germany

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http://dx.doi.org/10.1128/IAI.00329-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803337PMC
November 2019

[Experience of disease, relationship and sexuality in patients with COPD].

Z Psychosom Med Psychother 2019 Sep;65(3):257-271

Lindenhofspital Bern Bremgartenstrasse 117 3001 Bern Schweiz Lindenhofspital Bern.

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http://dx.doi.org/10.13109/zptm.2019.65.3.257DOI Listing
September 2019

IL-17C-mediated innate inflammation decreases the response to PD-1 blockade in a model of Kras-driven lung cancer.

Sci Rep 2019 07 17;9(1):10353. Epub 2019 Jul 17.

Department of Internal Medicine V - Pulmonology, Allergology and Respiratory Critical Care Medicine, Saarland University, 66421, Homburg, Germany.

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http://dx.doi.org/10.1038/s41598-019-46759-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637115PMC
July 2019

Myeloid cell-derived LL-37 promotes lung cancer growth by activating Wnt/β-catenin signaling.

Theranostics 2019 12;9(8):2209-2223. Epub 2019 Apr 12.

Department of Clinical Laboratory, Shanghai Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, China.

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http://dx.doi.org/10.7150/thno.30726DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531301PMC
June 2020

Liver Fibrosis and Metabolic Alterations in Adults With alpha-1-antitrypsin Deficiency Caused by the Pi*ZZ Mutation.

Gastroenterology 2019 09 20;157(3):705-719.e18. Epub 2019 May 20.

Coordinating Center for Alpha1-Antitrypsin Deficiency-Related Liver Disease of the European Reference Network "Rare Liver" and the European Association for the Study of the Liver Registry Group "Alpha1-Liver," University Hospital Aachen, Aachen, Germany; Medical Clinic III, Gastroenterology, Metabolic Diseases and Intensive Care, University Hospital Rheinisch-Westfälische Technische Hochschule Aachen, Aachen, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00165085194089
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http://dx.doi.org/10.1053/j.gastro.2019.05.013DOI Listing
September 2019

Effects of airway obstruction and hyperinflation on electrocardiographic axes in COPD.

Respir Res 2019 Mar 27;20(1):61. Epub 2019 Mar 27.

Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, Ludwig Maximilians University (LMU), Comprehensive Pneumology Center Munich (CPC-M), Member of the German Center for Lung Research (DZL), Ziemssenstrasse 1, 80336, Munich, Germany.

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http://dx.doi.org/10.1186/s12931-019-1025-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437876PMC
March 2019

A murine model to study vasoreactivity and intravascular flow in lung isograft microvessels.

Sci Rep 2019 03 26;9(1):5170. Epub 2019 Mar 26.

Department of Internal Medicine V - Pulmonology, Allergology, Respiratory Intensive Care Medicine, Saarland University Hospital, 66424, Homburg, Germany.

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http://dx.doi.org/10.1038/s41598-019-41590-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435642PMC
March 2019

Profiling of Alzheimer's disease related genes in mild to moderate vitamin D hypovitaminosis.

J Nutr Biochem 2019 05 11;67:123-137. Epub 2019 Feb 11.

Experimental Neurology, Saarland University, Kirrberger Str. 1, 66421 Homburg/Saar, Germany; Neurodegeneration and Neurobiology, Saarland University, Kirrberger Str. 1, 66421 Homburg/Saar, Germany; Deutsches Institut für DemenzPrävention (DIDP), Saarland University, Kirrberger Str. 1, 66421 Homburg/Saar, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jnutbio.2019.01.015DOI Listing
May 2019

COPD: Rethinking Patient Management - How to Approach a Challenging Patient Group Successfully.

Respiration 2019 15;97(4):363-368. Epub 2019 Mar 15.

Clinic for Pneumology and Allergology, Centre of Sleep Medicine and Respiratory Care, Bethanien Hospital, Institute of Pneumology, University of Cologne, Solingen, Germany.

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http://dx.doi.org/10.1159/000493759DOI Listing
August 2020

The composition of the pulmonary microbiota in sarcoidosis - an observational study.

Respir Res 2019 Feb 28;20(1):46. Epub 2019 Feb 28.

Department of Internal Medicine V - Pulmonology, Allergology, Critical Care Medicine, Saarland University Hospital, Homburg, Germany.

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https://respiratory-research.biomedcentral.com/articles/10.1
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http://dx.doi.org/10.1186/s12931-019-1013-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396534PMC
February 2019

Electronic cigarettes: a task force report from the European Respiratory Society.

Eur Respir J 2019 02 31;53(2). Epub 2019 Jan 31.

Dept of Pathophysiology and Transplantation, Università degli Studi di Milano, Internal Medicine Department, Respiratory Unit and Regional Adult Cystic Fibrosis Center, IRCCS Fondazione Cà Granda Ospedale Maggiore Policlinico, Milan, Italy.

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http://dx.doi.org/10.1183/13993003.01151-2018DOI Listing
February 2019

Longitudinal stability of blood eosinophil count strata in the COPD COSYCONET cohort.

Int J Chron Obstruct Pulmon Dis 2018 28;13:2999-3002. Epub 2018 Sep 28.

Pulmonary Research Institute at Lungen Clinic Grosshansdorf, Airway Research Center North (ARCN), Member of the German Centre for Lung Research (DZL), Grosshansdorf, Germany.

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https://www.dovepress.com/longitudinal-stability-of-blood-eo
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http://dx.doi.org/10.2147/COPD.S165909DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168004PMC
March 2019

Improving Outcomes in Bridge-to-Transplant: Extended Extracorporeal Membrane Oxygenation Support to Obtain Optimal Donor Lungs for Marginal Recipients.

ASAIO J 2019 07;65(5):516-521

Department of Internal Medicine V, Pneumology and Intensive Care Medicine, Saarland University Medical Center, Homburg/Saar, Germany.

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http://dx.doi.org/10.1097/MAT.0000000000000843DOI Listing
July 2019

Genome-wide MicroRNA Expression Profiles in COPD: Early Predictors for Cancer Development.

Genomics Proteomics Bioinformatics 2018 06 5;16(3):162-171. Epub 2018 Jul 5.

Department of Internal Medicine V - Pulmonology, Allergology, Intensive Care Medicine, Saarland University Hospital, 66421 Homburg, Germany.

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http://dx.doi.org/10.1016/j.gpb.2018.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076380PMC
June 2018

Uric acid, lung function, physical capacity and exacerbation frequency in patients with COPD: a multi-dimensional approach.

Respir Res 2018 06 4;19(1):110. Epub 2018 Jun 4.

Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, Comprehensive Pneumology Center Munich (CPC-M), Ludwig-Maximilians-Universität München, Ziemssenstr. 1, 80336, Munich, Germany.

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http://dx.doi.org/10.1186/s12931-018-0815-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987642PMC
June 2018

Murine alveolar epithelial cells and their lentivirus-mediated immortalisation.

Altern Lab Anim 2018 May;46(2):73-89

Department of Drug Delivery (DDEL), Helmholtz-Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz-Centre for Infection Research (HZI ), Saarbrücken, Germany; Department of Pharmacy, Saarland University, Saarbrücken, Germany; PharmBioTec GmbH, Saarbrücken, Germany.

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http://dx.doi.org/10.1177/026119291804600207DOI Listing
May 2018

Weaning from prolonged veno-venous extracorporeal membrane oxygenation (ECMO) after transfer to a specialized center: a retrospective study.

J Artif Organs 2018 Sep 15;21(3):300-307. Epub 2018 May 15.

Department of Internal Medicine V, Pneumology, Allergology, and Critical Care Medicine, Saarland University Medical Center, 66421, Homburg, Germany.

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http://dx.doi.org/10.1007/s10047-018-1046-1DOI Listing
September 2018

Cerebral oxygen availability during exercise in COPD patients with cognitive impairment.

Respir Physiol Neurobiol 2018 08 2;254:64-72. Epub 2018 May 2.

Department of Respiratory Medicine & Exercise Therapy, Schoen Klinik Berchtesgadener Land, Schoenau am Koenigssee, Germany; Department of Pulmonary Rehabilitation, Philipps University Marburg, Marburg, Germany; German Center of Lung Research (DZL), Giessen-Marburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.resp.2018.05.001DOI Listing
August 2018

Decreased Migration of Dendritic Cells into the Jugular-Nodose Ganglia by the CXCL12 Neutraligand Chalcone 4 in Ovalbumin-Sensitized Asthmatic Mice.

Neuroimmunomodulation 2017 20;24(6):331-340. Epub 2018 Apr 20.

Department of Experimental Pneumology and Allergology, Internal Medicine V, Faculty of Medicine, Saarland University, Homburg, Germany.

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http://dx.doi.org/10.1159/000487140DOI Listing
January 2019

Left ventricular volume and wall stress are linked to lung function impairment in COPD.

Int J Cardiol 2018 06;261:172-178

Department of Medicine, Pulmonary and Critical Care Medicine, Philipps University of Marburg, Member of the German Centre for Lung Research (DZL), Marburg, Germany.

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http://dx.doi.org/10.1016/j.ijcard.2018.02.074DOI Listing
June 2018

Airway obstruction and lung hyperinflation in COPD are linked to an impaired left ventricular diastolic filling.

Respir Med 2018 04 19;137:14-22. Epub 2018 Feb 19.

Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, Ludwig Maximilians University, Comprehensive Pneumology Centre Munich (CPC-M), Member of the German Centre for Lung Research (DZL), Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.rmed.2018.02.011DOI Listing
April 2018

Effects of E-Cigarette Use on Human Lung Tissue. On Harm Reduction and Causing Harm.

Am J Respir Crit Care Med 2018 07;198(1):6-7

2 Department of Internal Medicine V-Pulmonology, Allergology and Critical Care Medicine Saarland University Homburg, Germany.

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http://dx.doi.org/10.1164/rccm.201802-0299EDDOI Listing
July 2018

Percutaneous Mechanical Circulation Support Combined with Extracorporeal Membrane Oxygenation (oxyRVAD) in Secondary Right Heart Failure.

ASAIO J 2018 Jul/Aug;64(4):e64-e67

From the Department of Internal Medicine V-Pneumology, Allergology and Critical Care Medicine, University Hospital of Saarland, Homburg/Saar, Germany and University of Saarland, Saarbrücken.

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http://dx.doi.org/10.1097/MAT.0000000000000754DOI Listing
March 2019

The revised GOLD 2017 COPD categorization in relation to comorbidities.

Respir Med 2018 01 5;134:79-85. Epub 2017 Dec 5.

Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, Comprehensive Pneumology Center Munich (CPC-M), Ludwig-Maximilians-Universität München, Ziemssenstr. 1, 80336 Munich, Germany.

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http://dx.doi.org/10.1016/j.rmed.2017.12.003DOI Listing
January 2018

Intensive smoking diminishes the differences in quality of life and exacerbation frequency between the alpha-1-antitrypsin deficiency genotypes PiZZ and PiSZ.

Respir Med 2017 Sep 8;130:1-8. Epub 2017 Jul 8.

Department of Internal Medicine V - Pulmonology, Allergology, Intensive Care Medicine, Saarland University, Homburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.rmed.2017.07.004DOI Listing
September 2017

Cardiovascular risk in patients with alpha-1-antitrypsin deficiency.

Respir Res 2017 09 15;18(1):171. Epub 2017 Sep 15.

Department of Internal Medicine V, Pulmonology, Allergology, Intensive Care Medicine, Saarland University Hospital, 66424, Homburg, Germany.

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http://dx.doi.org/10.1186/s12931-017-0655-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602961PMC
September 2017

Extracorporeal membrane oxygenation (ECMO) as salvage treatment for pulmonary Echinococcus granulosus infection with acute cyst rupture.

Int J Infect Dis 2017 Nov 8;64:47-49. Epub 2017 Sep 8.

Department of Medicine V - Pneumology, Allergology and Critical Care Medicine, ECLS Centre Saar, Saarland University, Homburg/Saar, Germany.

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http://dx.doi.org/10.1016/j.ijid.2017.09.001DOI Listing
November 2017

Exacerbations and duration of smoking abstinence are associated with the annual loss of FEV in individuals with PiZZ alpha-1-antitrypsin deficiency.

Respir Med 2017 08 24;129:8-15. Epub 2017 May 24.

Department of Internal Medicine V - Pulmonology, Allergology, Intensive Care Medicine, Saarland University, Homburg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09546111173015
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http://dx.doi.org/10.1016/j.rmed.2017.05.011DOI Listing
August 2017

Receptor for advanced glycation endproducts (RAGE) maintains pulmonary structure and regulates the response to cigarette smoke.

PLoS One 2017 5;12(7):e0180092. Epub 2017 Jul 5.

Department of Internal Medicine V - Pulmonology, Allergology and Critical Care Medicine, Saarland University, Homburg, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0180092PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497997PMC
September 2017

Deterioration of quality of life is associated with the exacerbation frequency in individuals with alpha-1-antitrypsin deficiency - analysis from the German Registry.

Int J Chron Obstruct Pulmon Dis 2017 12;12:1427-1437. Epub 2017 May 12.

Department of Internal Medicine V - Pulmonology, Allergology, Intensive Care Medicine, Saarland University Hospital, Homburg.

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http://dx.doi.org/10.2147/COPD.S130925DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439990PMC
March 2018

Three-dimensional ultrashort echo time MRI and Short T images generated from subtraction for determination of tumor burden in lung cancer: Preclinical investigation in transgenic mice.

Magn Reson Med 2018 02 11;79(2):1052-1060. Epub 2017 May 11.

Department of Internal Medicine V-Pulmonology, Allergology, and Respiratory Critical Care Medicine, Saarland University Hospital, Homburg, Germany.

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http://doi.wiley.com/10.1002/mrm.26741
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http://dx.doi.org/10.1002/mrm.26741DOI Listing
February 2018

Costs and health-related quality of life in Alpha-1-Antitrypsin Deficient COPD patients.

Respir Res 2017 04 17;18(1):60. Epub 2017 Apr 17.

Institute of Health Economics and Health Care Management, Helmholtz Zentrum München, GmbH, German Research Center for Environmental Health, Comprehensive Pneumology Center Munich (CPC-M), Member of the German Center for Lung Research, Ingolstaedter Landstr. 1, 85764, Neuherberg, Germany.

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http://dx.doi.org/10.1186/s12931-017-0543-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392996PMC
April 2017

Hypoxia and the hypoxia-regulated transcription factor HIF-1α suppress the host defence of airway epithelial cells.

Innate Immun 2017 05 8;23(4):373-380. Epub 2017 Mar 8.

1 Department of Internal Medicine V - Pulmonology, Allergology and Critical Care Medicine, Saarland University, Homburg, Germany.

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http://dx.doi.org/10.1177/1753425917698032DOI Listing
May 2017

Allergic airway inflammation induces migration of mast cell populations into the mouse airway.

Cell Tissue Res 2017 08 25;369(2):331-340. Epub 2017 Mar 25.

Department of Experimental Pneumology and Allergology, Saarland University Hospital and Saarland University Faculty of Medicine, Kirrberger Strasse, Geb. 61.4, 66421, Homburg/Saar, Germany.

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http://dx.doi.org/10.1007/s00441-017-2597-9DOI Listing
August 2017

Nontypeable Haemophilus influenzae-Promoted Proliferation of Kras-Induced Early Adenomatous Lesions Is Completely Dependent on Toll-Like Receptor Signaling.

Am J Pathol 2017 May 6;187(5):973-979. Epub 2017 Mar 6.

Department of Internal Medicine V-Pulmonology, Allergology and Respiratory Critical Care Medicine, Saarland University, Homburg/Saar, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2017.01.003DOI Listing
May 2017

The Homburg Lung: Efficacy and Safety of a Minimal-Invasive Pump-Driven Device for Veno-Venous Extracorporeal Carbon Dioxide Removal.

ASAIO J 2017 Sep/Oct;63(5):659-665

From the *Department of Internal Medicine V-Pneumology, Allergology and Critical Care Medicine, Saarland University Medical Center, Homburg, Germany; †Department of Thoracic and Cardiac Surgery, Division of Cardiovascular Perfusion, Saarland University Medical Center, Homburg, Germany; ‡Maquet Clinical Concepts, MaquetGetinge Group, Rastatt, Germany; §Department of Anaesthesiology, University Hospital of Würzburg, Würzburg, Germany; and ¶Kliniken Maria Hilf, Division of Cardiology, Electrophysiology and Critical Care Medicine, Mönchengladbach, Germany.

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http://dx.doi.org/10.1097/MAT.0000000000000522DOI Listing
April 2018

Transfer factor for carbon monoxide in patients with COPD and diabetes: results from the German COSYCONET cohort.

Respir Res 2017 01 13;18(1):14. Epub 2017 Jan 13.

Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, Ludwig-Maximilians-Universität München, Ziemssenstr. 1, 80336, Munich, Germany.

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http://dx.doi.org/10.1186/s12931-016-0499-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237203PMC
January 2017

Increase of Mast Cell-Nerve Association and Neuropeptide Receptor Expression on Mast Cells in Perennial Allergic Rhinitis.

Neuroimmunomodulation 2016 29;23(5-6):261-270. Epub 2016 Dec 29.

Department of Experimental Pneumology and Allergology, Saarland University Hospital, Homburg, Germany.

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http://dx.doi.org/10.1159/000453068DOI Listing
February 2018

Local Effects on Airway Inflammation and Systemic Uptake of 5 nm PEGylated and Citrated Gold Nanoparticles in Asthmatic Mice.

Small 2017 03 23;13(10). Epub 2016 Dec 23.

Department of Experimental Pneumology and Allergology, Saarland University Faculty of Medicine, Kirrberger Str. 100, D-66421, Homburg/Saar, Germany.

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http://dx.doi.org/10.1002/smll.201603070DOI Listing
March 2017

Outcome of a four-hour smoking cessation counselling workshop for medical students.

Tob Induc Dis 2016 25;14:37. Epub 2016 Nov 25.

Division of Pulmonary Medicine, Internal Medicine, University Hospitals of Homburg/ Saar, Saarland University, Homburg/Saar, Germany.

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http://dx.doi.org/10.1186/s12971-016-0103-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123240PMC
November 2016

Calcifediol-loaded liposomes for local treatment of pulmonary bacterial infections.

Eur J Pharm Biopharm 2017 Sep 22;118:62-67. Epub 2016 Nov 22.

Helmholtz-Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz-Institute for Infection Research (HZI), Saarbrücken, Germany; Department of Pharmacy, Saarland University, Saarbrücken, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejpb.2016.11.026DOI Listing
September 2017

Bilateral Endoscopic Lung Volume Reduction in Patients with Severe Emphysema.

Respiration 2016 5;92(5):356-358. Epub 2016 Oct 5.

Department of Internal Medicine V - Pneumology, Allergology, and Critical Care Medicine, University Hospital of Saarland, Homburg, Germany.

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http://dx.doi.org/10.1159/000450758DOI Listing
September 2017

Basic science of electronic cigarettes: assessment in cell culture and in vivo models.

Respir Res 2016 10 7;17(1):127. Epub 2016 Oct 7.

Department of Internal Medicine V - Pulmonology, Allergology and Critical Care Medicine, Saarland University, D-66421, Homburg, Germany.

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http://dx.doi.org/10.1186/s12931-016-0447-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055681PMC
October 2016

[Alpha-1-antitrypsin deficiency - an update].

Dtsch Med Wochenschr 2016 Sep 4;141(20):1467-1469. Epub 2016 Oct 4.

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http://dx.doi.org/10.1055/s-0042-112096DOI Listing
September 2016

IL-17A-mediated expression of epithelial IL-17C promotes inflammation during acute Pseudomonas aeruginosa pneumonia.

Am J Physiol Lung Cell Mol Physiol 2016 Nov 30;311(5):L1015-L1022. Epub 2016 Sep 30.

Department of Internal Medicine V-Pulmonology, Allergology and Respiratory Critical Care Medicine, Saarland University, Homburg, Germany;

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http://dx.doi.org/10.1152/ajplung.00158.2016DOI Listing
November 2016