Publications by authors named "Robert B Den"

100Publications

Use of combined androgen deprivation therapy with postoperative radiation treatment for prostate cancer: Impact of randomized trials on clinical practice.

Urol Oncol 2020 Jun 15. Epub 2020 Jun 15.

Department of Radiation Oncology, University of Toronto, Toronto, Canada; Radiation Medicine Program, Princess Margaret Cancer Centre, University Health Network, Canada; Techna Institute, University Health Network, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.urolonc.2020.04.019DOI Listing
June 2020

Implementation of Germline Testing for Prostate Cancer: Philadelphia Prostate Cancer Consensus Conference 2019.

J Clin Oncol 2020 Aug 9;38(24):2798-2811. Epub 2020 Jun 9.

Department of Urology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.20.00046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430215PMC
August 2020

Prognostic value of the SPOP mutant genomic subclass in prostate cancer.

Urol Oncol 2020 05 17;38(5):418-422. Epub 2020 Mar 17.

Department of Urology, New York Presbyterian Hospital, Joan and Sanford I. Weill Medical College of Cornell University, New York, NY; Sandra and Edward Meyer Cancer Center, Joan and Sanford I. Weill Medical College of Cornell University, New York, NY. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.urolonc.2020.02.011DOI Listing
May 2020

Comparing Radiotherapy to Prostatectomy for High-Risk Prostate Cancer: A Narrative Review of Mortality and Quality-of-Life Outcomes.

Cancer J 2020 Jan/Feb;26(1):29-37

From the Department of Radiation Oncology, Sidney Kimmel Medical College & Cancer Center at Thomas Jefferson University, Philadelphia, PA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/PPO.0000000000000420DOI Listing
January 2020

Fractionation scheme and treatment planning method for early glottic cancer in the United States: Economic impact of different medical decisions.

Head Neck 2020 Aug 24;42(8):1713-1720. Epub 2020 Jan 24.

Institute of Oncology, Davidoff Cancer Center, Rabin Medical Center, Israel.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hed.26082DOI Listing
August 2020

Combined Modality Therapies for High-Risk Prostate Cancer: Narrative Review of Current Understanding and New Directions.

Front Oncol 2019 29;9:1273. Epub 2019 Nov 29.

Department of Radiation Oncology, Sidney Kimmel Medical College and Cancer Center, Thomas Jefferson University, Philadelphia, PA, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fonc.2019.01273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896415PMC
November 2019

Comparison of Radical Prostatectomy Versus Radiation and Androgen Deprivation Therapy Strategies as Primary Treatment for High-risk Localized Prostate Cancer: A Systematic Review and Meta-analysis.

Eur Urol Focus 2020 03 5;6(2):404-418. Epub 2019 Dec 5.

Department of Radiation Oncology, Sidney Kimmel Medical College & Cancer Center at Thomas Jefferson University, Philadelphia, PA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.euf.2019.11.007DOI Listing
March 2020

Feasibility and Impact of Emotional Intelligence Evaluation in Radiation Oncology Residency Interviews.

J Am Coll Radiol 2020 Feb 19;17(2):289-292. Epub 2019 Oct 19.

Department of Radiation Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jacr.2019.09.011DOI Listing
February 2020

Decipher identifies men with otherwise clinically favorable-intermediate risk disease who may not be good candidates for active surveillance.

Prostate Cancer Prostatic Dis 2020 03 27;23(1):136-143. Epub 2019 Aug 27.

Department of Urology, University of California, San Francisco, Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41391-019-0167-9DOI Listing
March 2020

Overemphasis of Step 1 Scores May Affect Application Pool Diversity in Radiation Oncology.

Pract Radiat Oncol 2020 Jan - Feb;10(1):e3-e7. Epub 2019 Jul 29.

Department of Radiation Oncology, Sidney Kimmel Medical College & Cancer Center at Thomas Jefferson University, Philadelphia, Pennsylvania.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.prro.2019.07.009DOI Listing
June 2020

The Financial Impact of Fractionation Scheme and Treatment Planning Method for Rectal Cancer in the United States.

Clin Colorectal Cancer 2019 09 31;18(3):209-217. Epub 2019 May 31.

Institute of Oncology, Davidoff Cancer Center, Rabin Medical Center, Petach Tiqva, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; Department of Health Policy and Management, University of North Carolina, Chapel Hill, NC. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clcc.2019.05.005DOI Listing
September 2019

Characterization of transcriptomic signature of primary prostate cancer analogous to prostatic small cell neuroendocrine carcinoma.

Int J Cancer 2019 12 10;145(12):3453-3461. Epub 2019 Jun 10.

Department of Pathology & Laboratory Medicine, Arnie Charbonneau Cancer Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ijc.32430DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852174PMC
December 2019

The Financial Impact of Hypofractionated Radiation for Localized Prostate Cancer in the United States.

J Oncol 2019 2;2019:8170428. Epub 2019 Jan 2.

Institute of Oncology, Davidoff Cancer Center, Rabin Medical Center, Petah Tikva, Israel.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2019/8170428DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334370PMC
January 2019

NF-κB and GATA-Binding Factor 6 Repress Transcription of Caveolins in Bladder Smooth Muscle Hypertrophy.

Am J Pathol 2019 04 30;189(4):847-867. Epub 2019 Jan 30.

Department of Medicine, Center for Translational Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania; Division of Urology, University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajpath.2018.12.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458544PMC
April 2019

SpaceOAR to improve dosimetric outcomes for monotherapy high-dose-rate prostate implantation in a patient with ulcerative colitis.

J Contemp Brachytherapy 2018 Dec 28;10(6):577-582. Epub 2018 Dec 28.

Department of Radiation Oncology, Thomas Jefferson University Hospital, Philadelphia, PA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5114/jcb.2018.81001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335554PMC
December 2018

Patient-Centered Oncology or Population-Centered Oncology-Which Do We Want, and Which Tradeoffs Are We Willing To Accept?

Oncologist 2019 03 6;24(3):288-290. Epub 2018 Dec 6.

Department of Radiation Oncology, Jefferson University, Philadelphia, Pennsylvania, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1634/theoncologist.2018-0679DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519750PMC
March 2019

Avoidance sectors to reduce dosimetric impact of an irreproducible pannus on setup uncertainty in prostate SBRT VMAT: A case study.

Med Dosim 2019 Summer;44(2):179-182. Epub 2018 Aug 16.

Department of Radiation Oncology, Thomas Jefferson University Hospital, 111 S. 11th St., Philadelphia, PA 19107, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.meddos.2018.05.003DOI Listing
December 2019

Radiation Effect on Male Spermatogenesis and Fertility-The Science and Ethical Consideration of the Oregon and Washington Radiation Experiments on Prison Inmates.

Urology 2018 11 11;121:33-38. Epub 2018 Aug 11.

Department of Urology, Sidney Kimmel Medical College at Thomas Jefferson University Hospital, Philadelphia, PA 19107.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00904295183078
Publisher Site
http://dx.doi.org/10.1016/j.urology.2018.06.050DOI Listing
November 2018

Development and Validation of a 28-gene Hypoxia-related Prognostic Signature for Localized Prostate Cancer.

EBioMedicine 2018 May 23;31:182-189. Epub 2018 Apr 23.

Translational Radiobiology Group, Division of Cancer Sciences, University of Manchester, Manchester Academic Health Science Centre, Christie Hospital, Manchester M20 4BX, UK; NIHR Manchester Biomedical Research Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ebiom.2018.04.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014579PMC
May 2018

Clinical and Genomic Characterization of Low-Prostate-specific Antigen, High-grade Prostate Cancer.

Eur Urol 2018 08 22;74(2):146-154. Epub 2018 Feb 22.

Harvard Medical School, Boston, MA, USA; Department of Radiation Oncology, Brigham and Women's Hospital/Dana-Farber Cancer Institute, Boston, MA, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.eururo.2018.01.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615042PMC
August 2018

Utilizing 10-Year Results From the American Board of Radiology Clinical Examination to Identify Areas for Programmatic Improvement.

Int J Radiat Oncol Biol Phys 2018 03 27;100(3):556-557. Epub 2017 Nov 27.

Department of Radiation Oncology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, Pennsylvania.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijrobp.2017.11.032DOI Listing
March 2018

Role of Genetic Testing for Inherited Prostate Cancer Risk: Philadelphia Prostate Cancer Consensus Conference 2017.

J Clin Oncol 2018 02 13;36(4):414-424. Epub 2017 Dec 13.

Veda N. Giri, Karen E. Knudsen, William K. Kelly, Robert B. Den, Adam P. Dicker, Jean Hoffman-Censits, Mark D. Hurwitz, Colette Hyatt, Grace Lu-Yao, Mark J. Mann, James R. Mark, Peter A. McCue, Ronald E. Myers, Stephen C. Peiper, Edouard J. Trabulsi, and Leonard G. Gomella, Jefferson Sidney Kimmel Cancer Center; Justin E. Bekelman, University of Pennsylvania Perelman School of Medicine; S. Bruce Malkowicz, University of Pennsylvania; Elias Obeid and Robert Uzzo, Fox Chase Cancer Center; Gordon F. Schwartz, Foundation for Breast and Prostate Health, Philadelphia; Mark S. Shahin, Hanjani Institute for Gynecologic Oncology, Abington Hospital-Jefferson Health, Abington, PA; Wassim Abida, Philip Kantoff, and Mark E. Robson, Memorial Sloan Kettering Cancer Center; Mitchell C. Benson, Columbia University, New York, NY; Gerald L. Andriole, Washington University School of Medicine, St Louis, MO; Chris H. Bangma, Erasmus Medical Center, Rotterdam, the Netherlands; Amie Blanco, and Matthew Cooperberg, University of California, San Francisco Helen Diller Family Comprehensive Cancer Center, San Francisco; Christopher J. Kane, University of California San Diego, San Diego; Howard Sandler, Cedars-Sinai Medical Center, Los Angeles; Howard R. Soule, Prostate Cancer Foundation, Santa Monica, CA; Arthur Burnett, William B. Isaacs, Christian P. Pavlovich, and Patrick C. Walsh, Johns Hopkins Medical Institutions, Baltimore; Peter A. Pinto and Carol J. Weil, National Cancer Institute, Bethesda, MD; William J. Catalona and Edward Schaeffer, Northwestern University Feinberg School of Medicine; Scott Eggener, Sarah M. Nielsen, and Donald J. Vander Griend, University of Chicago, Chicago, IL; Kathleen A. Cooney, University of Utah School of Medicine, Salt Lake City, UT; David E. Crawford, University of Colorado, Aurora; Lawrence I. Karsh, The Urology Center of Colorado, Denver; Wendy Poage, Prostate Conditions Education Council, Elizabeth, CO; Neil Fleshner, University of Toronto Princess Margaret Cancer Centre, Toronto, Ontario, Canada; Matthew L. Freedman, Kevin R. Loughlin, and Timothy R. Rebbeck, Dana Farber Cancer Institute, and Harvard TH Chan School of Public Health, Boston, MA; Freddie C. Hamdy, University of Oxford, Oxford, England; R. Jeffrey Karnes, Mayo Clinic, Rochester, MN; Eric A. Klein, Cleveland Clinic, Cleveland; Robert Pilarski, The Ohio State University, Columbus, OH; Daniel W. Lin, University of Washington, Seattle, WA; Martin M. Miner, Brown University, Providence, RI; Todd Morgan and Scott A. Tomlins, University of Michigan, Ann Arbor; Matt T. Rosenberg, Mid-Michigan Health Center, Jackson, MI; Judd W. Moul, Duke University, Duke Cancer Institute, Durham, NC; David F. Penson, Vanderbilt University Medical Center, Nashville, TN; Daniel Petrylak and Brian Shuch, Yale University, New Haven, CT; Curtis A. Pettaway, The University of Texas MD Anderson Cancer Center, Houston; Ganesh V. Raj, University of Texas Southwestern Medical Center at Dallas, Dallas, TX; Oliver Sartor, Tulane University Medical School, New Orleans, LA; Neal D. Shore, Atlantic Urology Clinics/Carolina Urologic Research Center, Myrtle Beach, SC; and Richard Wender, American Cancer Society, Atlanta, GA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2017.74.1173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075860PMC
February 2018

Development and Validation of a Novel Integrated Clinical-Genomic Risk Group Classification for Localized Prostate Cancer.

J Clin Oncol 2018 02 29;36(6):581-590. Epub 2017 Nov 29.

Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra, University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System, Detroit, MI; Jingbin Zhang, María Santiago-Jiménez, Lucia L.C. Lam, Jijumon Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki, Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, British Columbia, Canada; John W. Davis, The University of Texas MD Anderson Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J. Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane, University of California San Diego, San Diego; Edward Uchio, University of California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore, MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland, OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University, Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

View Article

Download full-text PDF

Source
http://ascopubs.org/doi/10.1200/JCO.2017.74.2940
Publisher Site
http://dx.doi.org/10.1200/JCO.2017.74.2940DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530900PMC
February 2018

The Role of Genomic Techniques in Predicting Response to Radiation Therapy.

Oncology (Williston Park) 2017 07;31(7):562-70

View Article

Download full-text PDF

Source
July 2017

Low rates of androgen deprivation therapy use with salvage radiation therapy in patients with prostate cancer after radical prostatectomy.

Urol Oncol 2017 09 19;35(9):542.e25-542.e32. Epub 2017 May 19.

Harvard Medical School, Boston, MA; Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Boston, MA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.urolonc.2017.04.018DOI Listing
September 2017

Individual Patient-Level Meta-Analysis of the Performance of the Decipher Genomic Classifier in High-Risk Men After Prostatectomy to Predict Development of Metastatic Disease.

J Clin Oncol 2017 Jun 30;35(18):1991-1998. Epub 2017 Mar 30.

Daniel E. Spratt and Shuang G. Zhao, University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System, Detroit, MI; Kasra Yousefi, Samineh Deheshi, Jingbin Zhang, Lucia L.C. Lam, Marguerite du Plessis, Voleak Choeurng, Zaid Haddad, Christine Buerki, and Elai Davicioni, GenomeDx Biosciences, Vancouver, British Columbia, Canada; Ashley E. Ross and Bruce J. Trock, Johns Hopkins Hospital, Baltimore, MD; Robert B. Den and Adam P. Dicker, Thomas Jefferson University, Philadelphia, PA; Edward M. Schaeffer, Northwestern University, Evanston, IL; Andrew G. Glass and Sheila Weinmann, Center for Health Research, Kaiser Permanente Northwest, Portland, OR; Stephen J. Freedland, Cedars-Sinai Medical Center, Los Angeles; Felix Y. Feng, University of California, San Francisco, CA; Eric A. Klein, Cleveland Clinic, Cleveland, OH; and R. Jeffrey Karnes, Mayo Clinic, Rochester, MN.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2016.70.2811DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530581PMC
June 2017

Genomic Classifier Augments the Role of Pathological Features in Identifying Optimal Candidates for Adjuvant Radiation Therapy in Patients With Prostate Cancer: Development and Internal Validation of a Multivariable Prognostic Model.

J Clin Oncol 2017 Jun 28;35(18):1982-1990. Epub 2017 Mar 28.

Deepansh Dalela, Mani Menon, and Firas Abdollah, Henry Ford Health System, Detroit, MI; María Santiago-Jiménez, Kasra Yousefi, and Elai Davicioni, GenomeDx Biosciences, Vancouver, British Columbia, Canada; R. Jeffrey Karnes, Mayo Clinic, Rochester, MN; Ashley E. Ross, Johns Hopkins Hospital, Baltimore, MD; Adam P. Dicker and Robert B. Den, Thomas Jefferson University, Philadelphia, PA; Stephen J. Freedland, Cedars-Sinai Medical Center, Los Angeles, CA; Edward M. Schaeffer, Northwestern University Feinberg School of Medicine, Chicago, IL; and Alberto Briganti, Vita Salute San Raffaele Hospital, Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2016.69.9918DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530898PMC
June 2017

Stromal Gene Expression is Predictive for Metastatic Primary Prostate Cancer.

Eur Urol 2018 04 19;73(4):524-532. Epub 2017 Mar 19.

Vancouver Prostate Centre & Laboratory for Advanced Genome Analysis, Department of Urologic Sciences, University of British Columbia, Vancouver, BC, Canada; School of Computing Sciences, Simon Fraser University, Burnaby, BC, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.eururo.2017.02.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685211PMC
April 2018

siRNA-Encapsulated Hybrid Nanoparticles Target Mutant K-ras and Inhibit Metastatic Tumor Burden in a Mouse Model of Lung Cancer.

Mol Ther Nucleic Acids 2017 Mar 31;6:259-268. Epub 2016 Dec 31.

Department of Pharmaceutical Science, College of Pharmacy, Thomas Jefferson University, Philadelphia, PA 19107, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.omtn.2016.12.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363504PMC
March 2017

Transcriptome evaluation of the relation between body mass index and prostate cancer outcomes.

Cancer 2017 Jun 31;123(12):2240-2247. Epub 2017 Jan 31.

Department of Radiation Oncology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, Pennsylvania.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cncr.30580DOI Listing
June 2017

Increasing faculty participation in resident education and providing cost-effective self-assessment module credit to faculty through resident-generated didactics.

Pract Radiat Oncol 2017 Jul - Aug;7(4):241-245. Epub 2016 Dec 16.

Department of Radiation Oncology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, Pennsylvania. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.prro.2016.12.003DOI Listing
March 2018

Radioisotopes in management of metastatic prostate cancer.

Indian J Urol 2016 Oct-Dec;32(4):277-281

Department of Radiation Oncology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/0970-1591.189708DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054657PMC
November 2016

Multi-institutional Analysis Shows that Low PCAT-14 Expression Associates with Poor Outcomes in Prostate Cancer.

Eur Urol 2017 02 22;71(2):257-266. Epub 2016 Jul 22.

Department of Internal Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, MO, USA; Alvin J. Siteman Cancer Center, Washington University School of Medicine, St. Louis, MO, USA; Beaumont Hospital-Dearborn, Transitional Year Program, Dearborn, MI, USA; Department of Biomedical Engineering, Washington University School of Medicine, St. Louis, MO, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.eururo.2016.07.012DOI Listing
February 2017

Development and validation of a 24-gene predictor of response to postoperative radiotherapy in prostate cancer: a matched, retrospective analysis.

Lancet Oncol 2016 Nov 12;17(11):1612-1620. Epub 2016 Oct 12.

Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA; Michigan Center for Translational Pathology, Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI, USA; Department of Radiation Oncology, University of California at San Francisco, San Francisco, CA, USA; Department of Medicine, University of California at San Francisco, San Francisco, CA, USA; Helen Diller Comprehensive Cancer Center, University of California at San Francisco, San Francisco, CA, USA. Electronic address:

View Article

Download full-text PDF

Source
http://www.thelancet.com/pdfs/journals/lanonc/PIIS1470-2045(
Web Search
http://dx.doi.org/10.1016/S1470-2045(16)30491-0DOI Listing
November 2016

Prognostic outlier genes for enhanced prostate cancer treatment.

Future Oncol 2017 Feb 12;13(3):249-261. Epub 2016 Oct 12.

Department of Radiation Oncology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA 19107, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/fon-2016-0223DOI Listing
February 2017

Contemporary Update of a Multi-Institutional Predictive Nomogram for Salvage Radiotherapy After Radical Prostatectomy.

J Clin Oncol 2016 Oct;34(30):3648-3654

Rahul D. Tendulkar, Tianming Gao, Kevin L. Stephans, Michael W. Kattan, and Andrew J. Stephenson, Cleveland Clinic; Shree Agrawal, Case Western Reserve University School of Medicine, Cleveland, OH; Jason A. Efstathiou and Anthony L. Zietman, Massachusetts General Hospital, Boston, MA; Thomas M. Pisansky, Mayo Clinic, Rochester, MN; Jeff M. Michalski, Washington University, St Louis, MO; Bridget F. Koontz and W. Robert Lee, Duke University, Durham, NC; Daniel A. Hamstra, The Texas Center for Proton Therapy, Irving, TX; Felix Y. Feng, University of Michigan, Ann Arbor, MI; Stanley L. Liauw, University of Chicago, Chicago IL; Matthew C. Abramowitz and Alan Pollack, University of Miami, Miami, FL; Mitchell S. Anscher and Drew Moghanaki, Virginia Commonwealth University; Drew Moghanaki, Hunter Holmes McGuire Veterans Affairs Medical Center, Richmond, VA; and Robert B. Den, Thomas Jefferson University, Philadelphia, PA.

View Article

Download full-text PDF

Source
http://jco.ascopubs.org/content/early/2016/08/10/JCO.2016.67
Web Search
http://dx.doi.org/10.1200/JCO.2016.67.9647DOI Listing
October 2016

ASTRO APEx and RO-ILS™ are applicable to medical malpractice in radiation oncology.

Future Oncol 2016 Nov 29;12(22):2643-2657. Epub 2016 Jul 29.

Department of Radiation Oncology, Jefferson Medical College of Thomas Jefferson University, Philadelphia, PA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/fon-2016-0131DOI Listing
November 2016

Dosing, administration, and safety of radium-223: How I do it.

Can J Urol 2016 Jun;23(3):8301-5

Department of Radiation Oncology, Sidney Kimmel Cancer Center, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.

View Article

Download full-text PDF

Source
June 2016

The Missing Pieces in Reporting of Randomized Controlled Trials of External Beam Radiation Therapy Dose Escalation for Prostate Cancer.

Am J Clin Oncol 2016 08;39(4):321-6

*Department of Radiation Oncology, Fox Chase Cancer Center †Department of Radiation Oncology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA ‡Department of Radiation Oncology, Brigham and Women's Hospital, Boston, MA §Department of Radiation Oncology, University of Virginia Health System, Charlottesville, VA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/COC.0000000000000313DOI Listing
August 2016

Integrated Classification of Prostate Cancer Reveals a Novel Luminal Subtype with Poor Outcome.

Cancer Res 2016 09 14;76(17):4948-58. Epub 2016 Jun 14.

Division of Cancer Biology and Therapeutics, Departments of Surgery & Biomedical Sciences, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047668PMC
http://dx.doi.org/10.1158/0008-5472.CAN-16-0902DOI Listing
September 2016

Impact of Radiation Therapy Dose Escalation on Prostate Cancer Outcomes and Toxicities.

Am J Clin Oncol 2018 04;41(4):409-415

Department of Radiation Oncology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/COC.0000000000000285DOI Listing
April 2018

Association Between Treatment at a High-Volume Facility and Improved Survival for Radiation-Treated Men With High-Risk Prostate Cancer.

Int J Radiat Oncol Biol Phys 2016 Mar 14;94(4):683-90. Epub 2015 Dec 14.

Department of Radiation Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, Massachusetts; Harvard Medical School, Boston, Massachusetts. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijrobp.2015.12.008DOI Listing
March 2016

Biodistribution and Pharmacokinetics Study of siRNA-loaded Anti-NTSR1-mAb-functionalized Novel Hybrid Nanoparticles in a Metastatic Orthotopic Murine Lung Cancer Model.

Mol Ther Nucleic Acids 2016 Jan 26;5:e282. Epub 2016 Jan 26.

Department of Pharmaceutical Science, College of Pharmacy, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/mtna.2015.56DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012553PMC
January 2016

AXIN2 expression predicts prostate cancer recurrence and regulates invasion and tumor growth.

Prostate 2016 May 15;76(6):597-608. Epub 2016 Jan 15.

Division of Medical Oncology, Department of Medicine, University of Southern California Keck School of Medicine and Translational and Clinical Science Program, USC Norris Comprehensive Cancer Center, Los Angeles, California.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pros.23151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455032PMC
May 2016

A single activity with a practice quality improvement project for faculty and a quality improvement project for residents.

Pract Radiat Oncol 2016 Mar-Apr;6(2):114-8. Epub 2015 Oct 28.

Department of Radiation Oncology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, Pennsylvania.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.prro.2015.10.014DOI Listing
January 2017

The Landscape of Prognostic Outlier Genes in High-Risk Prostate Cancer.

Clin Cancer Res 2016 Apr 2;22(7):1777-86. Epub 2015 Dec 2.

Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan. Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, Michigan. Comprehensive Cancer Center, University of Michigan, Ann Arbor, Michigan.

View Article

Download full-text PDF

Source
http://clincancerres.aacrjournals.org/content/early/2016/01/
Web Search
http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
Publisher Site
http://dx.doi.org/10.1158/1078-0432.CCR-15-1250DOI Listing
April 2016

DNA-PKcs-Mediated Transcriptional Regulation Drives Prostate Cancer Progression and Metastasis.

Cancer Cell 2015 Jul;28(1):97-113

Department of Cancer Biology, Thomas Jefferson University, Philadelphia, PA 19107, USA; Department of Urology, Thomas Jefferson University, Philadelphia, PA 19107, USA; Department of Radiation Oncology, Thomas Jefferson University, Philadelphia, PA 19107, USA; Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccell.2015.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531387PMC
July 2015

What is the ideal radiotherapy dose to treat prostate cancer? A meta-analysis of biologically equivalent dose escalation.

Radiother Oncol 2015 Jun 28;115(3):295-300. Epub 2015 May 28.

Department of Radiation Oncology, Sidney Kimmel Cancer Center at Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.radonc.2015.05.011DOI Listing
June 2015

Quercetin regulates β-catenin signaling and reduces the migration of triple negative breast cancer.

Mol Carcinog 2016 May 12;55(5):743-56. Epub 2015 May 12.

Department of Pharmaceutical Sciences, Jefferson School of Pharmacy, Thomas Jefferson University, Philadelphia, Pennsylvania.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mc.22318DOI Listing
May 2016

Characterization of 1577 primary prostate cancers reveals novel biological and clinicopathologic insights into molecular subtypes.

Eur Urol 2015 Oct 8;68(4):555-67. Epub 2015 May 8.

Michigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, MI, USA; Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, MI, USA; Department of Radiation Oncology, University of Michigan Medical School, Ann Arbor, MI, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.eururo.2015.04.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562381PMC
October 2015

Hematologic Toxicity of Concurrent Administration of Radium-223 and Next-generation Antiandrogen Therapies.

Am J Clin Oncol 2017 Aug;40(4):342-347

Departments of *Radiation Oncology †Medical Oncology ‡Urology, Kimmel Cancer Center, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/COC.0000000000000181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549230PMC
August 2017

Novel actions of next-generation taxanes benefit advanced stages of prostate cancer.

Clin Cancer Res 2015 Feb;21(4):795-807

Department of Cancer Biology, Thomas Jefferson University, Philadelphia, Pennsylvania. Department of Radiation Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania. Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania. Department of Medical Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania. Department of Urology, Thomas Jefferson University, Philadelphia, Pennsylvania.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-14-1358DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333741PMC
February 2015

Genomic classifier identifies men with adverse pathology after radical prostatectomy who benefit from adjuvant radiation therapy.

J Clin Oncol 2015 Mar 9;33(8):944-51. Epub 2015 Feb 9.

Robert B. Den, Edouard J. Trabulsi, Adam P. Dicker, Costas D. Lallas, and Leonard G. Gomella, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA; Firas Abdollah, Vattikuti Urology Institute, Henry Ford Hospital, Detroit; Felix Y. Feng, University of Michigan, Ann Arbor, MI; R. Jeffrey Karnes, Mayo Clinic, Rochester, MN; and Kasra Yousefi, Voleak Choeurng, and Elai Davicioni, GenomeDx Biosciences, Vancouver, British Columbia, Canada.

View Article

Download full-text PDF

Source
http://jco.ascopubs.org/content/early/2015/02/03/JCO.2014.59
Web Search
http://www.pcf.org/atf/cf/%7B7c77d6a2-5859-4d60-af47-132fd0f
Web Search
http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2014.59.0026
Publisher Site
http://dx.doi.org/10.1200/JCO.2014.59.0026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884273PMC
March 2015

RNA biomarkers associated with metastatic progression in prostate cancer: a multi-institutional high-throughput analysis of SChLAP1.

Lancet Oncol 2014 Dec 17;15(13):1469-1480. Epub 2014 Nov 17.

Michigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, MI, USA; Department of Radiation Oncology, University of Michigan Medical School, Ann Arbor, MI, USA; Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, MI, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S1470-2045(14)71113-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559342PMC
December 2014

Effect of docetaxel on safety and efficacy of radium-223.

Lancet Oncol 2014 Nov 17;15(12):1292-3. Epub 2014 Oct 17.

Department of Urology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA; Department of Medical Oncology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S1470-2045(14)71026-5DOI Listing
November 2014