Publications by authors named "Robert Adalbert"

28Publications

Protection against oxaliplatin-induced mechanical and thermal hypersensitivity in Sarm1 mice.

Authors:
Stacey Anne Gould Matthew White Anna L Wilbrey Erzsébet Pór Michael Philip Coleman Robert Adalbert

Exp Neurol 2021 Jan 15:113607. Epub 2021 Jan 15.

John van Geest Centre for Brain Repair, University of Cambridge, Cambridge, UK; The Babraham Institute, Cambridge, UK; Department of Anatomy, Histology and Embryology, Faculty of Medicine, University of Szeged, Szeged H-6724, Hungary. Electronic address:

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January 2021

Human endogenous retrovirus HERV-K(HML-2) RNA causes neurodegeneration through Toll-like receptors.

Authors:
Paul Dembny Andrew G Newman Manvendra Singh Michael Hinz Michal Szczepek Christina Krüger Robert Adalbert Omar Dzaye Thorsten Trimbuch Thomas Wallach Gunnar Kleinau Katja Derkow Bernhard C Richard Carola Schipke Claus Scheidereit Harald Stachelscheid Douglas Golenbock Oliver Peters Michael Coleman Frank L Heppner Patrick Scheerer Victor Tarabykin Klemens Ruprecht Zsuzsanna Izsvák Jens Mayer Seija Lehnardt

JCI Insight 2020 04 9;5(7). Epub 2020 Apr 9.

Institute of Cell Biology and Neurobiology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Berlin, Germany.

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April 2020

Novel HDAC6 Inhibitors Increase Tubulin Acetylation and Rescue Axonal Transport of Mitochondria in a Model of Charcot-Marie-Tooth Type 2F.

Authors:
Robert Adalbert Akira Kaieda Christina Antoniou Andrea Loreto Xiuna Yang Jonathan Gilley Takashi Hoshino Keiko Uga Mahindra T Makhija Michael P Coleman

ACS Chem Neurosci 2020 02 8;11(3):258-267. Epub 2020 Jan 8.

John van Geest Centre for Brain Repair, Department of Clinical Neurosciences , University of Cambridge , Forvie Site Robinson Way , Cambridge CB2 0PY , United Kingdom.

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February 2020

Publisher Correction: TDP-43 gains function due to perturbed autoregulation in a Tardbp knock-in mouse model of ALS-FTD.

Authors:
Matthew A White Eosu Kim Amanda Duffy Robert Adalbert Benjamin U Phillips Owen M Peters Jodie Stephenson Sujeong Yang Francesca Massenzio Ziqiang Lin Simon Andrews Anne Segonds-Pichon Jake Metterville Lisa M Saksida Richard Mead Richard R Ribchester Youssef Barhomi Thomas Serre Michael P Coleman Justin R Fallon Timothy J Bussey Robert H Brown Jemeen Sreedharan

Nat Neurosci 2018 Aug;21(8):1138

The Babraham Institute, Cambridge, UK.

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August 2018

Interaction between a MAPT variant causing frontotemporal dementia and mutant APP affects axonal transport.

Authors:
Robert Adalbert Stefan Milde Claire Durrant Kunie Ando Virginie Stygelbout Zehra Yilmaz Stacey Gould Jean-Pierre Brion Michael P Coleman

Neurobiol Aging 2018 08 5;68:68-75. Epub 2018 Apr 5.

Signalling Programme, The Babraham Institute, Babraham Research Campus, Cambridge, UK; John van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.

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August 2018

TDP-43 gains function due to perturbed autoregulation in a Tardbp knock-in mouse model of ALS-FTD.

Authors:
Matthew A White Eosu Kim Amanda Duffy Robert Adalbert Benjamin U Phillips Owen M Peters Jodie Stephenson Sujeong Yang Francesca Massenzio Ziqiang Lin Simon Andrews Anne Segonds-Pichon Jake Metterville Lisa M Saksida Richard Mead Richard R Ribchester Youssef Barhomi Thomas Serre Michael P Coleman Justin R Fallon Timothy J Bussey Robert H Brown Jemeen Sreedharan

Nat Neurosci 2018 04 19;21(4):552-563. Epub 2018 Mar 19.

The Babraham Institute, Cambridge, UK.

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April 2018

Application of virtual screening to the discovery of novel nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with potential for the treatment of cancer and axonopathies.

Authors:
David E Clark Bohdan Waszkowycz Melanie Wong Peter M Lockey Robert Adalbert Jonathan Gilley Jonathan Clark Michael P Coleman

Bioorg Med Chem Lett 2016 06 16;26(12):2920-2926. Epub 2016 Apr 16.

The Babraham Institute, Babraham Research Campus, Babraham, Cambridge CB22 3AT, United Kingdom.

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June 2016

Axonal transport declines with age in two distinct phases separated by a period of relative stability.

Authors:
Stefan Milde Robert Adalbert M Handan Elaman Michael P Coleman

Neurobiol Aging 2015 Feb 28;36(2):971-81. Epub 2014 Sep 28.

Signalling ISP, The Babraham Institute, Babraham Research Campus, Cambridge, UK. Electronic address:

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February 2015

Age-related axonal swellings precede other neuropathological hallmarks in a knock-in mouse model of Huntington's disease.

Authors:
Martina Marangoni Robert Adalbert Lucie Janeckova Jane Patrick Jaskaren Kohli Michael P Coleman Laura Conforti

Neurobiol Aging 2014 Oct 9;35(10):2382-93. Epub 2014 May 9.

School of Life Sciences, The University of Nottingham Medical School, Queen's Medical Centre, Nottingham, UK. Electronic address:

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October 2014

Rescue of peripheral and CNS axon defects in mice lacking NMNAT2.

Authors:
Jonathan Gilley Robert Adalbert Gang Yu Michael P Coleman

J Neurosci 2013 Aug;33(33):13410-24

Signalling Programme, The Babraham Institute, Babraham Research Campus, Cambridge, CB22 3AT, United Kingdom.

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August 2013

dSarm/Sarm1 is required for activation of an injury-induced axon death pathway.

Authors:
Jeannette M Osterloh Jing Yang Timothy M Rooney A Nicole Fox Robert Adalbert Eric H Powell Amy E Sheehan Michelle A Avery Rachel Hackett Mary A Logan Jennifer M MacDonald Jennifer S Ziegenfuss Stefan Milde Ying-Ju Hou Carl Nathan Aihao Ding Robert H Brown Laura Conforti Michael Coleman Marc Tessier-Lavigne Stephan Züchner Marc R Freeman

Science 2012 Jul 7;337(6093):481-4. Epub 2012 Jun 7.

Department of Neurobiology, University of Massachusetts Medical School, Worcester, MA 01605, USA.

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July 2012

Modelling early responses to neurodegenerative mutations in mice.

Authors:
Jonathan Gilley Robert Adalbert Michael P Coleman

Biochem Soc Trans 2011 Aug;39(4):933-8

Laboratory of Signalling and Cell Fate, Babraham Institute, Cambridge CB22 3AT, UK.

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August 2011

A metabolomic study of the CRND8 transgenic mouse model of Alzheimer's disease.

Authors:
Reza M Salek Jing Xia Amy Innes Brian C Sweatman Robert Adalbert Suzanne Randle Eileen McGowan Piers C Emson Julian L Griffin

Neurochem Int 2010 Jul 14;56(8):937-47. Epub 2010 Apr 14.

Department of Biochemistry, The Hopkins Building, Tennis Court Road, University of Cambridge, Cambridge CB21QW, UK.

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July 2010

Wld S protein requires Nmnat activity and a short N-terminal sequence to protect axons in mice.

Authors:
Laura Conforti Anna Wilbrey Giacomo Morreale Lucie Janeckova Bogdan Beirowski Robert Adalbert Francesca Mazzola Michele Di Stefano Robert Hartley Elisabetta Babetto Trevor Smith Jonathan Gilley Richard A Billington Armando A Genazzani Richard R Ribchester Giulio Magni Michael Coleman

J Cell Biol 2009 Feb;184(4):491-500

Babraham Institute, Babraham Research Campus, Cambridge CB22 3AT, England, UK.

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February 2009

Severely dystrophic axons at amyloid plaques remain continuous and connected to viable cell bodies.

Authors:
Robert Adalbert Antal Nogradi Elisabetta Babetto Lucie Janeckova Simon A Walker Martin Kerschensteiner Thomas Misgeld Michael P Coleman

Brain 2009 Feb 5;132(Pt 2):402-16. Epub 2008 Dec 5.

The Babraham Institute, Babraham Research Campus, Babraham, Cambridge, UK.

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February 2009

VCP binding influences intracellular distribution of the slow Wallerian degeneration protein, Wld(S).

Authors:
Anna L Wilbrey Jane E Haley Thomas M Wishart Laura Conforti Giacomo Morreale Bogdan Beirowski Elisabetta Babetto Robert Adalbert Thomas H Gillingwater Trevor Smith David J A Wyllie Richard R Ribchester Michael P Coleman

Mol Cell Neurosci 2008 Jul 25;38(3):325-40. Epub 2008 Mar 25.

The Babraham Institute, Babraham Research Campus, Cambridge, CB22 3AT, UK.

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July 2008

Late onset distal axonal swelling in YFP-H transgenic mice.

Authors:
Katherine E Bridge Nicola Berg Robert Adalbert Elisabetta Babetto Tatyana Dias Maria-Grazia Spillantini Richard R Ribchester Michael P Coleman

Neurobiol Aging 2009 Feb 19;30(2):309-21. Epub 2007 Jul 19.

Laboratory of Molecular Signalling, Babraham Institute, Babraham, Cambridge CB22 3AT, UK.

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February 2009

Abeta, tau and ApoE4 in Alzheimer's disease: the axonal connection.

Authors:
Robert Adalbert Jonathan Gilley Michael P Coleman

Trends Mol Med 2007 Apr 6;13(4):135-42. Epub 2007 Mar 6.

The Babraham Institute, Babraham, Cambridge, UK.

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April 2007

Neuronal death: where does the end begin?

Authors:
Laura Conforti Robert Adalbert Michael P Coleman

Trends Neurosci 2007 Apr 6;30(4):159-66. Epub 2007 Mar 6.

The Babraham Institute, Babraham, Cambridge CB22 3AT, UK.

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April 2007

The slow Wallerian degeneration gene in vivo protects motor axons but not their cell bodies after avulsion and neonatal axotomy.

Authors:
Robert Adalbert Antal Nógrádi András Szabó Michael P Coleman

Eur J Neurosci 2006 Oct;24(8):2163-8

The Babraham Institute, Babraham, Cambridge CB2 4AT, UK.

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October 2006