Robert A Rissman

Robert A Rissman

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Robert A Rissman

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Neuroinflammation is associated with infiltration of T cells in Lewy body disease and α-synuclein transgenic models.

J Neuroinflammation 2020 Jul 17;17(1):214. Epub 2020 Jul 17.

Laboratory of Neurogenetics, Molecular Neuropathology Section, National Institute on Aging, National Institutes of Health, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1186/s12974-020-01888-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368752PMC
July 2020

Association of Neighborhood-Level Disadvantage With Alzheimer Disease Neuropathology.

JAMA Netw Open 2020 Jun 1;3(6):e207559. Epub 2020 Jun 1.

Department of Medicine, Geriatrics Division, University of Wisconsin School of Medicine and Public Health, Madison.

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http://dx.doi.org/10.1001/jamanetworkopen.2020.7559DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290421PMC
June 2020

The Area Deprivation Index: A novel tool for harmonizable risk assessment in Alzheimer's disease research.

Alzheimers Dement (N Y) 2020 14;6(1):e12039. Epub 2020 Jun 14.

Department of Medicine Division of Geriatrics University of Wisconsin School of Medicine and Public Health Madison Wisconsin USA.

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http://dx.doi.org/10.1002/trc2.12039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293995PMC
June 2020

Upregulation of RIN3 induces endosomal dysfunction in Alzheimer's disease.

Transl Neurodegener 2020 Jun 18;9(1):26. Epub 2020 Jun 18.

Department of Neurosciences, University of California San Diego School of Medicine, Room 312 MC-0624,9500 Gilman Drive, La Jolla, CA, 92093-0624, USA.

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http://dx.doi.org/10.1186/s40035-020-00206-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301499PMC
June 2020

Diverse proteins aggregate in mild cognitive impairment and Alzheimer's disease brain.

Alzheimers Res Ther 2020 Jun 19;12(1):75. Epub 2020 Jun 19.

Cellular Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, 92037, USA.

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http://dx.doi.org/10.1186/s13195-020-00641-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305608PMC
June 2020

Transcriptomic analysis of brain tissues identifies a role for CCAAT enhancer binding protein β in HIV-associated neurocognitive disorder.

J Neuroinflammation 2020 Apr 11;17(1):112. Epub 2020 Apr 11.

Department of Psychiatry, School of Medicine, University of California San Diego, 9500 Gilman Dr., BSB 3009, San Diego, La Jolla, CA, 92093-0603, USA.

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http://dx.doi.org/10.1186/s12974-020-01781-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7149918PMC
April 2020

Women can bear a bigger burden: ante- and post-mortem evidence for reserve in the face of tau.

Brain Commun 2020 14;2(1):fcaa025. Epub 2020 Apr 14.

Department of Neurosciences, University of California San Diego, La Jolla, CA 92093, USA.

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http://dx.doi.org/10.1093/braincomms/fcaa025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7166251PMC
April 2020

The GSM BPN-15606 as a Potential Candidate for Preventative Therapy in Alzheimer's Disease.

J Alzheimers Dis 2020 ;73(4):1541-1554

Department of Neurosciences, University of California San Diego, La Jolla, CA USA.

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http://dx.doi.org/10.3233/JAD-190442DOI Listing
January 2020

High-Throughput Mass Spectrometry Assay for Quantifying β-Amyloid 40 and 42 in Cerebrospinal Fluid.

Clin Chem 2019 12 18;65(12):1572-1580. Epub 2019 Oct 18.

Quest Diagnostics Nichols Institute, San Juan Capistrano, CA;

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http://dx.doi.org/10.1373/clinchem.2018.300947DOI Listing
December 2019

Reflections on the Utility of the Retina as a Biomarker for Alzheimer's Disease: A Literature Review.

Neurol Ther 2019 Dec 12;8(Suppl 2):57-72. Epub 2019 Dec 12.

Department of Neurosciences, University of California, San Diego, CA, USA.

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http://dx.doi.org/10.1007/s40120-019-00173-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908534PMC
December 2019

miR-212 and miR-132 Are Downregulated in Neurally Derived Plasma Exosomes of Alzheimer's Patients.

Front Neurosci 2019 26;13:1208. Epub 2019 Nov 26.

Laboratory for Neurodegenerative Disease Research, Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.

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http://dx.doi.org/10.3389/fnins.2019.01208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902042PMC
November 2019

Effects of single and combined immunotherapy approach targeting amyloid β protein and α-synuclein in a dementia with Lewy bodies-like model.

Alzheimers Dement 2019 09 1;15(9):1133-1148. Epub 2019 Aug 1.

Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA; VA San Diego Healthcare System, La Jolla, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2019.02.002DOI Listing
September 2019

Systemic peptide mediated delivery of an siRNA targeting α-syn in the CNS ameliorates the neurodegenerative process in a transgenic model of Lewy body disease.

Neurobiol Dis 2019 07 5;127:163-177. Epub 2019 Mar 5.

Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA; Veterans Affairs San Diego Healthcare System San Diego, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2019.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588505PMC
July 2019

Integrating Gene and Protein Expression Reveals Perturbed Functional Networks in Alzheimer's Disease.

Cell Rep 2019 07;28(4):1103-1116.e4

Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA; Veterans Affairs San Diego Healthcare System, San Diego, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.06.073DOI Listing
July 2019

Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD.

Authors:
Cyril Pottier Yingxue Ren Ralph B Perkerson Matt Baker Gregory D Jenkins Marka van Blitterswijk Mariely DeJesus-Hernandez Jeroen G J van Rooij Melissa E Murray Elizabeth Christopher Shannon K McDonnell Zachary Fogarty Anthony Batzler Shulan Tian Cristina T Vicente Billie Matchett Anna M Karydas Ging-Yuek Robin Hsiung Harro Seelaar Merel O Mol Elizabeth C Finger Caroline Graff Linn Öijerstedt Manuela Neumann Peter Heutink Matthis Synofzik Carlo Wilke Johannes Prudlo Patrizia Rizzu Javier Simon-Sanchez Dieter Edbauer Sigrun Roeber Janine Diehl-Schmid Bret M Evers Andrew King M Marsel Mesulam Sandra Weintraub Changiz Geula Kevin F Bieniek Leonard Petrucelli Geoffrey L Ahern Eric M Reiman Bryan K Woodruff Richard J Caselli Edward D Huey Martin R Farlow Jordan Grafman Simon Mead Lea T Grinberg Salvatore Spina Murray Grossman David J Irwin Edward B Lee EunRan Suh Julie Snowden David Mann Nilufer Ertekin-Taner Ryan J Uitti Zbigniew K Wszolek Keith A Josephs Joseph E Parisi David S Knopman Ronald C Petersen John R Hodges Olivier Piguet Ethan G Geier Jennifer S Yokoyama Robert A Rissman Ekaterina Rogaeva Julia Keith Lorne Zinman Maria Carmela Tartaglia Nigel J Cairns Carlos Cruchaga Bernardino Ghetti Julia Kofler Oscar L Lopez Thomas G Beach Thomas Arzberger Jochen Herms Lawrence S Honig Jean Paul Vonsattel Glenda M Halliday John B Kwok Charles L White Marla Gearing Jonathan Glass Sara Rollinson Stuart Pickering-Brown Jonathan D Rohrer John Q Trojanowski Vivianna Van Deerlin Eileen H Bigio Claire Troakes Safa Al-Sarraj Yan Asmann Bruce L Miller Neill R Graff-Radford Bradley F Boeve William W Seeley Ian R A Mackenzie John C van Swieten Dennis W Dickson Joanna M Biernacka Rosa Rademakers

Acta Neuropathol 2019 06 9;137(6):879-899. Epub 2019 Feb 9.

Department of Neuroscience, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.

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http://link.springer.com/10.1007/s00401-019-01962-9
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http://dx.doi.org/10.1007/s00401-019-01962-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533145PMC
June 2019

Early neuronal accumulation of DNA double strand breaks in Alzheimer's disease.

Acta Neuropathol Commun 2019 05 17;7(1):77. Epub 2019 May 17.

Gladstone Institute of Neurological Disease, San Francisco, CA, 94158, USA.

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http://dx.doi.org/10.1186/s40478-019-0723-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524256PMC
May 2019

Learnings about the complexity of extracellular tau aid development of a blood-based screen for Alzheimer's disease.

Alzheimers Dement 2019 03 9;15(3):487-496. Epub 2018 Nov 9.

Laboratory for Neurodegenerative Research, Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA; Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, England. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2018.09.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476313PMC
March 2019

Plasma Neurofilament Light and Alzheimer's Disease Biomarkers in Down Syndrome: Results from the Down Syndrome Biomarker Initiative (DSBI).

J Alzheimers Dis 2019 ;70(1):131-138

Department of Neurosciences, University of California, San Diego, San Diego, CA, USA.

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http://dx.doi.org/10.3233/JAD-190322DOI Listing
January 2019

Extracellular Vesicles Isolated from Familial Alzheimer's Disease Neuronal Cultures Induce Aberrant Tau Phosphorylation in the Wild-Type Mouse Brain.

J Alzheimers Dis 2019 ;72(2):575-585

University of California, San Diego, Department of Neurosciences, La Jolla, CA, USA.

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http://dx.doi.org/10.3233/JAD-190656DOI Listing
January 2019

T-complex protein 1-ring complex enhances retrograde axonal transport by modulating tau phosphorylation.

Traffic 2018 11 12;19(11):840-853. Epub 2018 Sep 12.

Department of Neurosciences, University of California San Diego, La Jolla, California.

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http://dx.doi.org/10.1111/tra.12610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191364PMC
November 2018

Targeted Mutation (R100W) of the Gene Encoding NGF Leads to Deficits in the Peripheral Sensory Nervous System.

Front Aging Neurosci 2018 13;10:373. Epub 2018 Nov 13.

Department of Neurosciences, University of California, San Diego, San Diego, CA, United States.

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http://dx.doi.org/10.3389/fnagi.2018.00373DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262302PMC
November 2018

Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study.

Authors:
Cyril Pottier Xiaolai Zhou Ralph B Perkerson Matt Baker Gregory D Jenkins Daniel J Serie Roberta Ghidoni Luisa Benussi Giuliano Binetti Adolfo López de Munain Miren Zulaica Fermin Moreno Isabelle Le Ber Florence Pasquier Didier Hannequin Raquel Sánchez-Valle Anna Antonell Albert Lladó Tammee M Parsons NiCole A Finch Elizabeth C Finger Carol F Lippa Edward D Huey Manuela Neumann Peter Heutink Matthis Synofzik Carlo Wilke Robert A Rissman Jaroslaw Slawek Emilia Sitek Peter Johannsen Jørgen E Nielsen Yingxue Ren Marka van Blitterswijk Mariely DeJesus-Hernandez Elizabeth Christopher Melissa E Murray Kevin F Bieniek Bret M Evers Camilla Ferrari Sara Rollinson Anna Richardson Elio Scarpini Giorgio G Fumagalli Alessandro Padovani John Hardy Parastoo Momeni Raffaele Ferrari Francesca Frangipane Raffaele Maletta Maria Anfossi Maura Gallo Leonard Petrucelli EunRan Suh Oscar L Lopez Tsz H Wong Jeroen G J van Rooij Harro Seelaar Simon Mead Richard J Caselli Eric M Reiman Marwan Noel Sabbagh Mads Kjolby Anders Nykjaer Anna M Karydas Adam L Boxer Lea T Grinberg Jordan Grafman Salvatore Spina Adrian Oblak M-Marsel Mesulam Sandra Weintraub Changiz Geula John R Hodges Olivier Piguet William S Brooks David J Irwin John Q Trojanowski Edward B Lee Keith A Josephs Joseph E Parisi Nilüfer Ertekin-Taner David S Knopman Benedetta Nacmias Irene Piaceri Silvia Bagnoli Sandro Sorbi Marla Gearing Jonathan Glass Thomas G Beach Sandra E Black Mario Masellis Ekaterina Rogaeva Jean-Paul Vonsattel Lawrence S Honig Julia Kofler Amalia C Bruni Julie Snowden David Mann Stuart Pickering-Brown Janine Diehl-Schmid Juliane Winkelmann Daniela Galimberti Caroline Graff Linn Öijerstedt Claire Troakes Safa Al-Sarraj Carlos Cruchaga Nigel J Cairns Jonathan D Rohrer Glenda M Halliday John B Kwok John C van Swieten Charles L White Bernardino Ghetti Jill R Murell Ian R A Mackenzie Ging-Yuek R Hsiung Barbara Borroni Giacomina Rossi Fabrizio Tagliavini Zbigniew K Wszolek Ronald C Petersen Eileen H Bigio Murray Grossman Vivianna M Van Deerlin William W Seeley Bruce L Miller Neill R Graff-Radford Bradley F Boeve Dennis W Dickson Joanna M Biernacka Rosa Rademakers

Lancet Neurol 2018 06 30;17(6):548-558. Epub 2018 Apr 30.

Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(18)30126-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237181PMC
June 2018

Deleterious Effect of Butyrylcholinesterase K-Variant in Donepezil Treatment of Mild Cognitive Impairment.

J Alzheimers Dis 2017 ;56(1):229-237

Indiana University School of Medicine, Indiana Alzheimer's Disease Center, Indianapolis, IN, USA.

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http://dx.doi.org/10.3233/JAD-160562DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5534361PMC
February 2018

Novel human neuronal tau model exhibiting neurofibrillary tangles and transcellular propagation.

Neurobiol Dis 2017 Oct 10;106:222-234. Epub 2017 Jun 10.

Department of Neurosciences, University of California, San Diego, School of Medicine, La Jolla, CA 92093, United States. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2017.06.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593133PMC
October 2017

Corticotropin-releasing factor receptor-1 modulates biomarkers of DNA oxidation in Alzheimer's disease mice.

PLoS One 2017 27;12(7):e0181367. Epub 2017 Jul 27.

Department of Neurosciences, University of California, San Diego School of Medicine, La Jolla, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0181367PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531470PMC
September 2017

Differential effects of immunotherapy with antibodies targeting α-synuclein oligomers and fibrils in a transgenic model of synucleinopathy.

Neurobiol Dis 2017 Aug 2;104:85-96. Epub 2017 May 2.

Department of Neurosciences, University of California, San Diego, La Jolla, CA 92093, United States; Veterans Affairs San Diego Healthcare System, San Diego, CA 92161, United States. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2017.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954414PMC
August 2017

Pharmacological and Toxicological Properties of the Potent Oral -Secretase Modulator BPN-15606.

J Pharmacol Exp Ther 2017 07 17;362(1):31-44. Epub 2017 Apr 17.

Department of Neurosciences, University of California, San Diego, La Jolla, California (S.L.W., K.D.R., P.D.N., A.B., U.V., D.M., L.M., W.C.M., R.A.R.); Integrated Nonclinical Development Solutions, Ann Arbor, Michigan (S.K.D.); NuPharmAdvise, Sanbornton, New Hampshire (G.J.); Biopharm Consulting Partners, Ambler, Pennsylvania (J.H.L.); and Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital, Charlestown, Massachusetts (C.Z., J.B.K., C.M.E., W.X., L.Q., D.Y.K., R.E.T.).

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http://jpet.aspetjournals.org/lookup/doi/10.1124/jpet.117.24
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http://dx.doi.org/10.1124/jpet.117.240861DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454592PMC
July 2017

A phase 3 trial of IV immunoglobulin for Alzheimer disease.

Neurology 2017 May 5;88(18):1768-1775. Epub 2017 Apr 5.

From Weill Cornell Medicine (N.R.R., P.S.), New York, NY; University of California (R.G.T., R.A.R., J.B.B.), San Diego; University of Southern California (M.S.R., R.R., P.S.A.), Los Angeles; Yale University (C.H.v.D.), New Haven, CT; Mayo Clinic (C.R.J., D.S.K.), Rochester, MN; Mount Sinai School of Medicine (M.S.), New York, NY; and Baxalta (D.M.G., S.F.), Bannockburn, IL.

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http://dx.doi.org/10.1212/WNL.0000000000003904DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409846PMC
May 2017

Lack of Influence of Apolipoprotein E Status on Cognition or Brain Structure in Professional Fighters.

J Neurotrauma 2017 01 27;34(2):380-384. Epub 2016 Jun 27.

1 Cleveland Clinic Lou Ruvo Center for Brain Health , Las Vegas, Nevada.

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http://dx.doi.org/10.1089/neu.2016.4453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220568PMC
January 2017

Blood-based biomarkers in Alzheimer disease: Current state of the science and a novel collaborative paradigm for advancing from discovery to clinic.

Alzheimers Dement 2017 01 18;13(1):45-58. Epub 2016 Nov 18.

AXA Research Fund and UPMC Chair, Paris, France; Department de Neurologie, Institut de la Memorie et de la Maladie d'Alzheimer (IM2A) et Institut du Cerveau et du la Moelle epiniere (ICM), Hospital de la Pitie-Salpetriere, Sorbonne Universites, Universite Pierre et Marie Curie, Paris, France.

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http://dx.doi.org/10.1016/j.jalz.2016.09.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5218961PMC
January 2017

Resveratrol regulates neuro-inflammation and induces adaptive immunity in Alzheimer's disease.

J Neuroinflammation 2017 01 3;14(1). Epub 2017 Jan 3.

Alzheimer's Disease Cooperative Study (ADCS), Department of Neurosciences, University of California, La Jolla, San Diego, CA, USA.

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http://dx.doi.org/10.1186/s12974-016-0779-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234138PMC
January 2017

Comparing biological markers of Alzheimer's disease across blood fraction and platforms: Comparing apples to oranges.

Alzheimers Dement (Amst) 2016 29;3:27-34. Epub 2015 Dec 29.

AXA Research Fund & UPMC Chair, Paris, France; Sorbonne Universités, Université Pierre et Marie Curie, Paris 06, Institut de la Mémoire et de la Maladie d'Alzheimer (IM2A) & Institut du Cerveau et de la Moelle épinière (ICM), Département de Neurologie, Hôpital de la Pitié-Salpétrière, Paris, France.

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http://dx.doi.org/10.1016/j.dadm.2015.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802360PMC
July 2016

Higher Brain Perfusion May Not Support Memory Functions in Cognitively Normal Carriers of the ApoE ε4 Allele Compared to Non-Carriers.

Front Aging Neurosci 2016 24;8:151. Epub 2016 Jun 24.

VA San Diego Healthcare SystemSan Diego, CA, USA; Department of Psychiatry, University of California San DiegoSan Diego, CA, USA.

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http://dx.doi.org/10.3389/fnagi.2016.00151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919360PMC
July 2016

Dissociation of Down syndrome and Alzheimer's disease effects with imaging.

Alzheimers Dement (N Y) 2016 Jun;2(2):69-81

Alzheimer's Disease Cooperative Study, Department of Neurosciences, University of California San Diego School of Medicine, La Jolla, CA, USA.

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http://dx.doi.org/10.1016/j.trci.2016.02.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477635PMC
June 2016

Reproductive Stage and Modulation of Stress-Induced Tau Phosphorylation in Female Rats.

J Neuroendocrinol 2015 Nov;27(11):827-34

Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.

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http://dx.doi.org/10.1111/jne.12323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625411PMC
November 2015

A randomized, double-blind, placebo-controlled trial of resveratrol for Alzheimer disease.

Neurology 2015 Oct 11;85(16):1383-91. Epub 2015 Sep 11.

From the Department of Neurology (R.S.T., B.A.R.), Georgetown University, Washington, DC; the Department of Neurosciences (R.G.T., J.B.B., R.A.R., R.R., P.S.A.), University of California, San Diego, La Jolla; the Department of Internal Medicine (S.C.), Wake Forest University, Winston-Salem, NC; the Departments of Psychiatry, Neurology, and Neurobiology (C.H.v.D.), Yale University, New Haven, CT; and the Clinical Biotechnology Research Institute (J.M.), Roper St. Francis Healthcare, Charleston, SC.

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http://www.neurology.org/content/early/2015/09/11/WNL.000000
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http://www.neurology.org/content/early/2015/09/11/WNL.000000
Web Search
http://www.neurology.org/cgi/doi/10.1212/WNL.000000000000203
Publisher Site
http://dx.doi.org/10.1212/WNL.0000000000002035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626244PMC
October 2015

The down syndrome biomarker initiative (DSBI) pilot: proof of concept for deep phenotyping of Alzheimer's disease biomarkers in down syndrome.

Front Behav Neurosci 2015 14;9:239. Epub 2015 Sep 14.

Alzheimer's Disease Cooperative Study, Department of Neurosciences, UC San Diego School of Medicine, University of California, San Diego La Jolla, CA, USA.

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http://dx.doi.org/10.3389/fnbeh.2015.00239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568340PMC
October 2015

Characterization of ATP alternations in an Alzheimer's disease transgenic mouse model.

J Alzheimers Dis 2015 ;44(2):375-8

Department of Biomedical Engineering, Louisiana Tech University, Ruston, LA, USA Division of Technology, Engineering and Mathematics, Bossier Parish Community College, Bossier City, LA, USA.

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http://dx.doi.org/10.3233/JAD-141890DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305018PMC
September 2015

Longitudinal plasma amyloid beta in Alzheimer's disease clinical trials.

Alzheimers Dement 2015 Sep 7;11(9):1069-79. Epub 2014 Oct 7.

Alzheimer's Disease Cooperative Study, Department of Neurosciences, University of California San Diego, School of Medicine, San Diego, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2014.07.156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387108PMC
September 2015

Oral glucose tolerance testing to modulate plasma amyloid levels: A novel biomarker.

Alzheimers Dement (Amst) 2015 Sep;1(3):311-315

Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1016/j.dadm.2015.06.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578701PMC
September 2015

Long-Term Electrophysiological and Behavioral Analysis on the Improvement of Visual Working Memory Load, Training Gains, and Transfer Benefits.

J Behav Brain Sci 2014 May;4(5):234-246

Applied Biology and Biomedical Engineering, Rose-Hulman Institute of Technology, Terre Haute, USA.

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http://dx.doi.org/10.4236/jbbs.2014.45025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101919PMC
May 2014

Interaction of age and APOE genotype on cerebral blood flow at rest.

J Alzheimers Dis 2013 ;34(4):921-35

Research Service, Veterans Affairs San Diego Healthcare System, San Diego, CA, USA.

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http://dx.doi.org/10.3233/JAD-121897DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124882PMC
September 2013

Detection and quantification of 8-hydroxy-2'-deoxyguanosine in Alzheimer's transgenic mouse urine using capillary electrophoresis.

Electrophoresis 2013 Aug 15;34(15):2268-74. Epub 2013 Jul 15.

Department of Neurosciences, UCSD School of Medicine, La Jolla, CA 92093, USA.

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http://dx.doi.org/10.1002/elps.201300036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789118PMC
August 2013

Longitudinal plasma amyloid beta as a biomarker of Alzheimer's disease.

J Neural Transm (Vienna) 2012 Jul 22;119(7):843-50. Epub 2012 Feb 22.

Alzheimer's Disease Cooperative Study, Department of Neurosciences, UCSD School of Medicine, La Jolla, CA 92037-0624, USA.

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http://dx.doi.org/10.1007/s00702-012-0772-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305447PMC
July 2012

Lipopolysaccharide-induced tau phosphorylation and kinase activity--modulation, but not mediation, by corticotropin-releasing factor receptors.

Eur J Neurosci 2011 Aug 4;34(3):448-56. Epub 2011 Jul 4.

Department of Neurosciences, University of California, San Diego School of Medicine, La Jolla, CA, USA.

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http://dx.doi.org/10.1111/j.1460-9568.2011.07764.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148267PMC
August 2011

The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers.

Alzheimers Dement 2011 Jul;7(4):386-395.e6

Clinical Neurochemistry Laboratory, Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, the Sahlgrenska Academy at the University of Gothenburg, Sahlgrenska University Hospital, Mölndal, Sweden.

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http://dx.doi.org/10.1016/j.jalz.2011.05.2243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710290PMC
July 2011

Implications for treatment: GABAA receptors in aging, Down syndrome and Alzheimer's disease.

J Neurochem 2011 May 28;117(4):613-22. Epub 2011 Mar 28.

Department of Neurosciences, University of California, San Diego, La Jolla, California 92093-0624, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2011.07237.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3127285PMC
May 2011

Stress-induced tau phosphorylation: functional neuroplasticity or neuronal vulnerability?

Authors:
Robert A Rissman

J Alzheimers Dis 2009 ;18(2):453-7

Department of Neurosciences, University of California, San Diego, La Jolla, CA 92037-0624, USA.

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http://dx.doi.org/10.3233/JAD-2009-1153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906152PMC
December 2009

Functional amyloids as natural storage of peptide hormones in pituitary secretory granules.

Science 2009 Jul 18;325(5938):328-32. Epub 2009 Jun 18.

Laboratory of Physical Chemistry, Eidgenössische Technische Hochschule (ETH) Zürich, Wolfgang-Paulistrasse 10, CH-8093 Zürich, Switzerland.

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http://dx.doi.org/10.1126/science.1173155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865899PMC
July 2009

GABA(A) receptors in aging and Alzheimer's disease.

J Neurochem 2007 Nov 20;103(4):1285-92. Epub 2007 Aug 20.

Laboratory of Neuronal Structure and Function, The Salk Institute for Biological Studies, La Jolla, California, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2007.04832.xDOI Listing
November 2007

Corticotropin-releasing factor receptors differentially regulate stress-induced tau phosphorylation.

J Neurosci 2007 Jun;27(24):6552-62

Laboratory of Neuronal Structure and Function, The Salk Institute for Biological Studies and Foundation for Medical Research, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.5173-06.2007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6672442PMC
June 2007

Age-related alterations in GABA(A) receptor subunits in the nonhuman primate hippocampus.

Brain Res 2006 Feb 20;1073-1074:120-30. Epub 2006 Jan 20.

Department of Neurobiology and Anatomy, Graduate Program in Neuroscience, MCP Hahnemann University School of Medicine, Philadelphia, PA 19102-1192, USA.

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http://dx.doi.org/10.1016/j.brainres.2005.12.036DOI Listing
February 2006

Caspase-cleaved tau accumulation in neurodegenerative diseases associated with tau and alpha-synuclein pathology.

Acta Neuropathol 2005 Aug 29;110(2):135-44. Epub 2005 Jun 29.

Department of Biology, Boise State University, Boise, Idaho, USA.

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http://dx.doi.org/10.1007/s00401-005-1027-3DOI Listing
August 2005

The role of caspase cleavage of tau in Alzheimer disease neuropathology.

J Neuropathol Exp Neurol 2005 Feb;64(2):104-12

Institute for Brain Aging and Dementia, University of California, Irvine, 92697, USA.

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http://dx.doi.org/10.1093/jnen/64.2.104DOI Listing
February 2005

Subregional analysis of GABA(A) receptor subunit mRNAs in the hippocampus of older persons with and without cognitive impairment.

J Chem Neuroanat 2004 Sep;28(1-2):17-25

Department of Neurobiology and Anatomy, Graduate Program in Neuroscience, MCP Hahnemann University School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.1016/j.jchemneu.2004.05.003DOI Listing
September 2004

Caspase-mediated degeneration in Alzheimer's disease.

Am J Pathol 2004 Aug;165(2):353-5

Institute for Brain Aging and Dementia, Irvine CA 92697-4540, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1618562PMC
http://dx.doi.org/10.1016/S0002-9440(10)63302-0DOI Listing
August 2004

Differential preservation of AMPA receptor subunits in the hippocampi of Alzheimer's disease patients according to Braak stage.

Exp Neurol 2004 Jun;187(2):299-309

Laboratory of Neuronal Vulnerability and Aging, The Lankenau Institute for Medical Research, Jefferson Health System, Wynewood, PA 19096, USA.

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http://dx.doi.org/10.1016/j.expneurol.2003.12.010DOI Listing
June 2004