Robert A Newman

Robert A Newman

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Robert A Newman

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The Botanical Glycoside Oleandrin Inhibits Human T-cell Leukemia Virus Type-1 Infectivity and Env-Dependent Virological Synapse Formation.

J Antivir Antiretrovir 2019 21;11(3). Epub 2019 Aug 21.

Laboratory of Molecular Virology, Department of Biological Sciences, The Dedman College Center for Drug Discovery, Design & Delivery, Southern Methodist University, Dallas, Texas, 75275-0376, USA.

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http://dx.doi.org/10.35248/1948-5964.19.11.184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904119PMC
August 2019

Sharp-Tailed Grouse Nest Survival and Nest Predator Habitat Use in North Dakota's Bakken Oil Field.

PLoS One 2017 12;12(1):e0170177. Epub 2017 Jan 12.

Department of Biology, University of North Dakota, Grand Forks, ND, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0170177PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5231376PMC
August 2017

Water-soluble egg membrane enhances the immunoactivating properties of an -based extract of leaves.

Clin Cosmet Investig Dermatol 2016 3;9:393-403. Epub 2016 Nov 3.

NIS Labs, Klamath Falls, OR.

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http://dx.doi.org/10.2147/CCID.S114471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098409PMC
November 2016

Pharmacokinetics in Mouse and Comparative Effects of Frondosides in Pancreatic Cancer.

Mar Drugs 2016 Jun 17;14(6). Epub 2016 Jun 17.

Department of Physiology, Faculty of Medicine, United Arab Emirates University, P.O. Box 17666, Al Ain, UAE.

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http://dx.doi.org/10.3390/md14060115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926074PMC
June 2016

Response to: Does the Nerium oleander extract PBI-05204 have potential for pancreatic cancer?

Invest New Drugs 2015 Jun 20;33(3):788-9. Epub 2015 Jan 20.

Department of Experimental Therapeutics, University of Texas, M. D. Anderson Cancer Center, Houston, TX, USA,

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http://dx.doi.org/10.1007/s10637-015-0208-8DOI Listing
June 2015

PBI-05204, a supercritical CO₂ extract of Nerium oleander, inhibits growth of human pancreatic cancer via targeting the PI3K/mTOR pathway.

Invest New Drugs 2015 Apr 6;33(2):271-9. Epub 2014 Dec 6.

Department of General Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 0462, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1007/s10637-014-0190-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387257PMC
April 2015

Cellular location and expression of Na+, K+ -ATPase α subunits affect the anti-proliferative activity of oleandrin.

Mol Carcinog 2014 Apr 16;53(4):253-63. Epub 2012 Oct 16.

Department of General Oncology, The University of Texas, M. D. Anderson Cancer Center, Houston, Texas; Department of Cancer Biology, The University of Texas, M. D. Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1002/mc.21968DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442617PMC
April 2014

BDNF mediates neuroprotection against oxygen-glucose deprivation by the cardiac glycoside oleandrin.

J Neurosci 2014 Jan;34(3):963-8

Center for Drug Discovery and Department of Neurobiology, Duke University Medical Center, Durham, North Carolina 27704, and Department of Experimental Therapeutics, The University of Texas, M. D. Anderson Cancer Center, Houston, Texas 77030.

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http://dx.doi.org/10.1523/JNEUROSCI.2700-13.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891971PMC
January 2014

Effects of host species and life stage on the helminth communities of sympatric northern leopard frogs (Lithobates pipiens) and wood frogs (Lithobates sylvaticus) in the Sheyenne National Grasslands, North Dakota.

J Parasitol 2013 Aug 14;99(4):587-94. Epub 2013 Feb 14.

Department of Zoology, Oklahoma State University, Life Sciences West, Stillwater, Oklahoma 74078, USA.

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http://dx.doi.org/10.1645/GE-3246.1DOI Listing
August 2013

Simultaneous reduction of particulate matter and NO(x) emissions using 4-way catalyzed filtration systems.

Environ Sci Technol 2013 May 15;47(9):4521-7. Epub 2013 Apr 15.

University of Minnesota, Department of Mechanical Engineering, 111 Church Street SE, Minneapolis, Minnesota 55455, USA.

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http://dx.doi.org/10.1021/es304971hDOI Listing
May 2013

Nerium oleander derived cardiac glycoside oleandrin is a novel inhibitor of HIV infectivity.

Fitoterapia 2013 Jan 2;84:32-9. Epub 2012 Nov 2.

Department of Immunology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1016/j.fitote.2012.10.017DOI Listing
January 2013

Arachidonic acid metabolism in human prostate cancer.

Int J Oncol 2012 Oct 10;41(4):1495-503. Epub 2012 Aug 10.

Department of General Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.3892/ijo.2012.1588DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982713PMC
October 2012

Zyflamend mediates therapeutic induction of autophagy to apoptosis in melanoma cells.

Nutr Cancer 2011 11;63(6):940-9. Epub 2011 Jul 11.

Department of Melanoma Medical Oncology, University of Texas, MD Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1080/01635581.2011.586488DOI Listing
December 2011

In vitro and in vivo neuroprotective activity of the cardiac glycoside oleandrin from Nerium oleander in brain slice-based stroke models.

J Neurochem 2011 Nov 26;119(4):805-14. Epub 2011 Sep 26.

Center for Drug Discovery and Department of Neurobiology, Duke University Medical Center, Durham, North Carolina 27514, USA.

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http://www.phoenixbiotechnology.com/documents/JournalOfNeuro
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http://doi.wiley.com/10.1111/j.1471-4159.2011.07439.x
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http://dx.doi.org/10.1111/j.1471-4159.2011.07439.xDOI Listing
November 2011

γ-Tocotrienol induces growth arrest through a novel pathway with TGFβ2 in prostate cancer.

Free Radic Biol Med 2011 May 16;50(10):1344-54. Epub 2011 Feb 16.

Department of Biochemistry and Molecular Biology, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN 37614, USA.

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http://dx.doi.org/10.1016/j.freeradbiomed.2011.02.007DOI Listing
May 2011

Human tumor cell sensitivity to oleandrin is dependent on relative expression of Na+, K+ -ATPase subunitst.

J Exp Ther Oncol 2010 ;8(4):271-86

Department of Experimental Therapeutics, The Univ. of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.

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February 2011

Profiling lipoxygenase metabolism in specific steps of colorectal tumorigenesis.

Cancer Prev Res (Phila) 2010 Jul 22;3(7):829-38. Epub 2010 Jun 22.

Department of Clinical Cancer Prevention, The University of Texas M.D. Anderson Cancer Center, Houston, 77030-4009, USA.

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http://dx.doi.org/10.1158/1940-6207.CAPR-09-0110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900425PMC
July 2010

Biological activity of celecoxib in the bronchial epithelium of current and former smokers.

Cancer Prev Res (Phila) 2010 Feb 26;3(2):148-59. Epub 2010 Jan 26.

Department of Thoracic/Head and Neck Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1158/1940-6207.CAPR-09-0233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028718PMC
February 2010

Pomegranate (Punica granatum) seed linolenic acid isomers: concentration-dependent modulation of estrogen receptor activity.

Endocr Res 2010 Jan;35(1):1-16

Department of Experimental Therapeutics, Kyungpook National University, Taegu, Republic of Korea.

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http://dx.doi.org/10.3109/07435800903524161DOI Listing
January 2010

Survival impact of integrative cancer care in advanced metastatic breast cancer.

Breast J 2009 Jul-Aug;15(4):357-66. Epub 2009 May 12.

Block Center for Integrative Cancer Treatment, Evanston, Illinois 60201, USA.

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http://dx.doi.org/10.1111/j.1524-4741.2009.00739.xDOI Listing
November 2009

Curcumin inhibits COPD-like airway inflammation and lung cancer progression in mice.

Carcinogenesis 2009 Nov 30;30(11):1949-56. Epub 2009 Sep 30.

Department of Pulmonary Medicine, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 1100, Houston, TX 77030, USA.

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http://dx.doi.org/10.1093/carcin/bgp229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783007PMC
November 2009

Phase I trial of a combination of the multikinase inhibitor sorafenib and the farnesyltransferase inhibitor tipifarnib in advanced malignancies.

Clin Cancer Res 2009 Nov 10;15(22):7061-8. Epub 2009 Nov 10.

Division of Cancer Medicine, Department of Investigational Therapeutics (Phase 1 Program), Unit 455, M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-09-1241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784003PMC
November 2009

Pomegranate fruit extract impairs invasion and motility in human breast cancer.

Integr Cancer Ther 2009 Sep;8(3):242-53

Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1177/1534735409341405DOI Listing
September 2009

Pharmacokinetics of caffeic acid phenethyl ester and its catechol-ring fluorinated derivative following intravenous administration to rats.

Biopharm Drug Dispos 2009 Jul;30(5):221-8

Pharmaceutics Division, College of Pharmacy, University of Texas at Austin, Austin, Texas 78712, USA.

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http://dx.doi.org/10.1002/bdd.657DOI Listing
July 2009

Determinants of human and mouse melanoma cell sensitivities to oleandrin.

J Exp Ther Oncol 2008 ;7(3):195-205

Postdoctoral Intramural Research Training Award Program, National Institute of Aging, National Institutes of Health, Baltimore, MD 21224, USA.

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January 2009

Re: Should supplemental antioxidant administration be avoided during chemotherapy and radiation therapy?

J Natl Cancer Inst 2009 Jan 13;101(2):124-5; author reply 125-6. Epub 2009 Jan 13.

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http://dx.doi.org/10.1093/jnci/djn446DOI Listing
January 2009

Rodent Plasmodium: population dynamics of early sporogony within Anopheles stephensi mosquitoes.

J Parasitol 2008 Oct;94(5):999-1008

Department of Biology, University of North Dakota, Grand Forks, North Dakota 58202, USA.

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http://dx.doi.org/10.1645/GE-1407.1DOI Listing
October 2008

Impact of antioxidant supplementation on chemotherapeutic toxicity: a systematic review of the evidence from randomized controlled trials.

Int J Cancer 2008 Sep;123(6):1227-39

Institute for Integrative Cancer Research and Education, Suite 350, Evanston, IL, USA.

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http://dx.doi.org/10.1002/ijc.23754DOI Listing
September 2008

Ficus spp. (fig): ethnobotany and potential as anticancer and anti-inflammatory agents.

J Ethnopharmacol 2008 Sep 28;119(2):195-213. Epub 2008 Jun 28.

Punisyn Pharmaceuticals, POB 9945, Haifa, Israel.

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http://dx.doi.org/10.1016/j.jep.2008.06.025DOI Listing
September 2008

Chemoprevention of 7,12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinogenesis in hamster cheek pouch by topical application of a dual inhibitor of epidermal growth factor receptor (EGFR) and ErbB2 tyrosine kinases.

Oral Oncol 2008 Jul 23;44(7):652-7. Epub 2007 Oct 23.

Cancer Research Program, Julius L. Chambers Biomedical/Biotechnology Research Institute, North Carolina Central University, 700 George Street, Durham, NC 27707, USA.

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http://dx.doi.org/10.1016/j.oraloncology.2007.08.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2546572PMC
July 2008

Phase II trial of curcumin in patients with advanced pancreatic cancer.

Clin Cancer Res 2008 Jul;14(14):4491-9

Department of Investigational Cancer Therapeutics, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-08-0024DOI Listing
July 2008

A classification model to predict synergism/antagonism of cytotoxic mixtures using protein-drug docking scores.

BMC Pharmacol 2008 Jul 29;8:13. Epub 2008 Jul 29.

Department of Experimental Therapeutics, University of Texas MD Anderson Cancer Center, Houston, TX 77054, USA.

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http://bmcpharma.biomedcentral.com/articles/10.1186/1471-221
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http://dx.doi.org/10.1186/1471-2210-8-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526994PMC
July 2008

Regulation of prostaglandin transporters in colorectal neoplasia.

Cancer Prev Res (Phila) 2008 Jul 19;1(2):93-9. Epub 2008 Mar 19.

Department of Cancer Biology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 118, Houston, TX 77030, USA.

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http://dx.doi.org/10.1158/1940-6207.CAPR-07-0009DOI Listing
July 2008

Structure-activity models of oral clearance, cytotoxicity, and LD50: a screen for promising anticancer compounds.

BMC Pharmacol 2008 Jun 13;8:12. Epub 2008 Jun 13.

Department of Experimental Therapeutics, University of Texas M, D, Anderson Cancer Center, 8000 El Rio, Houston, TX 77054, USA.

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http://link.springer.com/10.1186/1471-2210-8-12
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http://dx.doi.org/10.1186/1471-2210-8-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442056PMC
June 2008

Quantitative determination of fluorinated caffeic acid phenethyl ester derivative from rat blood plasma by liquid chromatography-electrospray ionization tandem mass spectrometry.

J Chromatogr B Analyt Technol Biomed Life Sci 2008 May 6;867(1):138-43. Epub 2008 Mar 6.

Pharmaceutics Division, College of Pharmacy, University of Texas at Austin, Austin, TX 78712, United States.

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http://dx.doi.org/10.1016/j.jchromb.2008.02.025DOI Listing
May 2008

Opposing effects of n-6 and n-3 polyunsaturated fatty acids on pancreatic cancer growth.

Pancreas 2008 May;36(4):353-62

Hirshberg Laboratories for Pancreatic Cancer Research, Department of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1097/MPA.0b013e31815ccc44DOI Listing
May 2008

Quantifying synergism/antagonism using nonlinear mixed-effects modeling: a simulation study.

Stat Med 2008 Mar;27(7):1040-61

Graduate School of Biomedical Sciences, University of Texas, Houston, TX, U.S.A.

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http://dx.doi.org/10.1002/sim.3005DOI Listing
March 2008

Bioavailability of curcumin: problems and promises.

Mol Pharm 2007 Nov-Dec;4(6):807-18. Epub 2007 Nov 14.

Cytokine Research Laboratory and Pharmaceutical Development Center, Department of Experimental Therapeutics, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1021/mp700113rDOI Listing
February 2008

Cardiac glycosides as novel cancer therapeutic agents.

Mol Interv 2008 Feb;8(1):36-49

Department of Experimental Therapeutics and Pharmaceutical Development Center, University of Texas, M. D. Anderson Cancer Center, Houston, TX 77054, USA.

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http://mr.crossref.org/iPage?doi=10.1124%2Fmi.8.1.8
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http://dx.doi.org/10.1124/mi.8.1.8DOI Listing
February 2008

The resistance to the tumor suppressive effects of COX inhibitors and COX-2 gene disruption in TRAMP mice is associated with the loss of COX expression in prostate tissue.

Carcinogenesis 2008 Jan 17;29(1):120-8. Epub 2007 Oct 17.

Department of Human Nutrition and Molecular Carcinogenesis and Chemoprevention Program, The Ohio State University Comprehensive Cancer Center, The Ohio State University, 325 Campbell Hall, 1787 Neil Avenue, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1093/carcin/bgm226DOI Listing
January 2008

Autophagic cell death of human pancreatic tumor cells mediated by oleandrin, a lipid-soluble cardiac glycoside.

Integr Cancer Ther 2007 Dec;6(4):354-64

Department of Experimental Therapeutics, University of Texas M. D. Anderson Cancer Center, Houston, Texas 77054, USA.

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http://dx.doi.org/10.1177/1534735407309623DOI Listing
December 2007

Comparative analysis of peritoneum and tumor eicosanoids and pathways in advanced ovarian cancer.

Clin Cancer Res 2007 Oct;13(19):5736-44

Department of Gynecologic Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77230, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-07-0583DOI Listing
October 2007

Silk-fibroin-coated liposomes for long-term and targeted drug delivery.

Int J Nanomedicine 2006 ;1(1):81-7

University of Texas MD Anderson Cancer Center, Laboratory of Reparative Biology and Bioengineering, Plastic Surgery, Houston, TX 72230, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2426758PMC
http://dx.doi.org/10.2147/nano.2006.1.1.81DOI Listing
September 2007

Impact of antioxidant supplementation on chemotherapeutic efficacy: a systematic review of the evidence from randomized controlled trials.

Cancer Treat Rev 2007 Aug 23;33(5):407-18. Epub 2007 Mar 23.

Institute for Integrative Cancer Research and Education, 1800 Sherman Avenue, Suite 350, Evanston, IL 60201, USA.

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http://dx.doi.org/10.1016/j.ctrv.2007.01.005DOI Listing
August 2007

Silk fibroin mediated delivery of liposomal emodin to breast cancer cells.

Int J Pharm 2007 Aug 3;341(1-2):221-9. Epub 2007 Apr 3.

University of Texas M.D. Anderson Cancer Center, Departments of Biomedical Engineering and Plastic Surgery, Unit 602, P.O. Box 301402, Houston, TX 72230-1402, United States.

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http://dx.doi.org/10.1016/j.ijpharm.2007.03.043DOI Listing
August 2007

Zyflamend, a polyherbal preparation, inhibits invasion, suppresses osteoclastogenesis, and potentiates apoptosis through down-regulation of NF-kappa B activation and NF-kappa B-regulated gene products.

Nutr Cancer 2007 ;57(1):78-87

Cytokine Research Laboratory, Department of Experimental Therapeutics, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1080/01635580701268295DOI Listing
July 2007

Simultaneous inhibition of COX-2 and 5-LOX activities augments growth arrest and death of premalignant and malignant human lung cell lines.

J Exp Ther Oncol 2007 ;6(3):183-92

Department of Thoracic, Head and Neck Medical Oncology, The University of Texas M. D. Anderson Cancer Center Houston, TX 77030, USA.

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July 2007

Zyflamend-mediated inhibition of human prostate cancer PC3 cell proliferation: effects on 12-LOX and Rb protein phosphorylation.

Cancer Biol Ther 2007 Feb 25;6(2):228-36. Epub 2007 Feb 25.

Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, 8000 El Rio Street, Houston, TX 77054, USA.

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http://dx.doi.org/10.4161/cbt.6.2.3624DOI Listing
February 2007

Punica granatum (pomegranate) and its potential for prevention and treatment of inflammation and cancer.

J Ethnopharmacol 2007 Jan 10;109(2):177-206. Epub 2006 Sep 10.

Punisyn Pharmaceuticals Ltd, Haifa, Israel.

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http://linkinghub.elsevier.com/retrieve/pii/S037887410600457
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http://dx.doi.org/10.1016/j.jep.2006.09.006DOI Listing
January 2007

Eupalmerin acetate, a novel anticancer agent from Caribbean gorgonian octocorals, induces apoptosis in malignant glioma cells via the c-Jun NH2-terminal kinase pathway.

Mol Cancer Ther 2007 Jan;6(1):184-92

Department of Neurosurgery, Unit BSRB1004, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-06-0422DOI Listing
January 2007

Determination of endogenous tissue inflammation profiles by LC/MS/MS: COX- and LOX-derived bioactive lipids.

Prostaglandins Leukot Essent Fatty Acids 2006 Dec 29;75(6):385-95. Epub 2006 Sep 29.

Departments of Experimental Therapeutics, The University of Texas, M.D. Anderson Cancer Center, 8000 El Rio, Houston, TX 77054, USA.

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http://dx.doi.org/10.1016/j.plefa.2006.07.015DOI Listing
December 2006

Involvement of the 5-lipoxygenase/leukotriene A4 hydrolase pathway in 7,12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinogenesis in hamster cheek pouch, and inhibition of carcinogenesis by its inhibitors.

Carcinogenesis 2006 Sep 21;27(9):1902-8. Epub 2006 Apr 21.

Cancer Research Program, Julius L. Chambers Biomedical/Biotechnology Research Institute, North Carolina Central University, NC 27707, USA.

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http://dx.doi.org/10.1093/carcin/bgl039DOI Listing
September 2006

A phase I trial to determine the optimal biological dose of celecoxib when combined with erlotinib in advanced non-small cell lung cancer.

Clin Cancer Res 2006 Jun;12(11 Pt 1):3381-8

Department of Medicine, Division of Hematology/Oncology, David Geffen School of Medicine at University of California at Los Angeles, 90095, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-06-0112DOI Listing
June 2006

Oleandrin-mediated oxidative stress in human melanoma cells.

J Exp Ther Oncol 2006 ;5(3):167-81

Department of Experimental Therapeutics, Univ. Texas M. D. Anderson Cancer Center, Houston, TX 77054, USA.

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May 2006

Evaluation of targeted arterial delivery of the branched chain fatty acid 12-methyltetradecanoic acid as a novel therapy for solid tumors.

J Exp Ther Oncol 2005 ;5(1):55-68

Section of Interventional Radiology, Department of Diagnostic Radiology, Unit 057, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030-4009, USA.

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March 2006

Curcumin suppresses the paclitaxel-induced nuclear factor-kappaB pathway in breast cancer cells and inhibits lung metastasis of human breast cancer in nude mice.

Clin Cancer Res 2005 Oct;11(20):7490-8

Cytokine Research Laboratory and Department of Experimental Therapeutics, University of Texas M.D. Anderson Cancer Center, Houston, Texas, 77030, USA.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-05-1192DOI Listing
October 2005

Activation of protein kinase G up-regulates expression of 15-lipoxygenase-1 in human colon cancer cells.

Cancer Res 2005 Sep;65(18):8442-7

Department of Medicine and Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, NY 10032, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-1109DOI Listing
September 2005

Suppression of prostate tumor cell growth by stromal cell prostaglandin D synthase-derived products.

Cancer Res 2005 Jul;65(14):6189-98

Department of Genitourinary Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-04-4439DOI Listing
July 2005

Cell-autonomous induction of functional tumor suppressor 15-lipoxygenase 2 (15-LOX2) contributes to replicative senescence of human prostate progenitor cells.

Oncogene 2005 May;24(22):3583-95

Department of Carcinogenesis, The University of Texas MD Anderson Cancer Center, Science Park-Research Division, 1808 Park Rd. 1C, Smithville, TX 78957, USA.

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http://dx.doi.org/10.1038/sj.onc.1208406DOI Listing
May 2005

Celecoxib inhibits prostate cancer growth: evidence of a cyclooxygenase-2-independent mechanism.

Clin Cancer Res 2005 Mar;11(5):1999-2007

Department of Medicine, Weill Medical College of Cornell University, 525 East 68th Street, New York, NY 10021, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-04-1877DOI Listing
March 2005

An antitumorigenic role for murine 8S-lipoxygenase in skin carcinogenesis.

Oncogene 2005 Feb;24(7):1174-87

Science Park-Research Division, University of Texas MD Anderson Cancer Center, 1808 Park Road 1C, PO Box 389, Smithville, TX 78957, USA.

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http://dx.doi.org/10.1038/sj.onc.1208269DOI Listing
February 2005

Cyclooxygenase-2 induction and prostaglandin E2 accumulation in squamous cell carcinoma as a consequence of epidermal growth factor receptor activation by imatinib mesylate.

J Exp Ther Oncol 2004 Dec;4(4):317-25

Department of Thoracic and Head and Neck Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.

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December 2004

Eicosanoid metabolism in squamous cell carcinoma cell lines derived from primary and metastatic head and neck cancer and its modulation by celecoxib.

Cancer Biol Ther 2004 Sep 18;3(9):847-52. Epub 2004 Sep 18.

Department of Thoracic, Head and Neck Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.4161/cbt.3.9.1037DOI Listing
September 2004

2004 Dr. Gary J. Becker Young Investigator Award: Relative thermosensitivity of cytotoxic drugs used in transcatheter arterial chemoembolization.

J Vasc Interv Radiol 2004 Sep;15(9):901-5

Department of Interventional Radiology, The University of Texas M. D. Anderson Cancer Center, Unit 325, 1515 Holcombe Boulevard, Houston, TX 77030-4009, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S105104430760493
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http://dx.doi.org/10.1097/01.RVI.0000136829.36643.EDDOI Listing
September 2004

Formation and antiproliferative effect of prostaglandin E(3) from eicosapentaenoic acid in human lung cancer cells.

J Lipid Res 2004 Jun 1;45(6):1030-9. Epub 2004 Mar 1.

Pharmaceutical Development Center, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77054, USA.

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http://dx.doi.org/10.1194/jlr.M300455-JLR200DOI Listing
June 2004

Final results of a phase I and pharmacokinetic study of gamma-methylene-10-deazaaminopterin (MDAM) administered intravenously daily for five consecutive days in patients with solid tumors.

Cancer Chemother Pharmacol 2004 May 18;53(5):370-6. Epub 2003 Dec 18.

Department of Experimental Therapeutics, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77054, USA.

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http://dx.doi.org/10.1007/s00280-003-0743-4DOI Listing
May 2004

Clinical evaluation of the delivery and safety of aerosolized liposomal 9-nitro-20(s)-camptothecin in patients with advanced pulmonary malignancies.

Clin Cancer Res 2004 Apr;10(7):2319-26

Cancer Research and Treatment Center, University of New Mexico, Albequerque, New Mexico 87131, USA.

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http://dx.doi.org/10.1158/1078-0432.ccr-0929-3DOI Listing
April 2004

Metabolism of homoharringtonine, a cytotoxic component of the evergreen plant Cephalotaxus harringtonia.

J Exp Ther Oncol 2003 Jan-Feb;3(1):47-52

Department of Experimental Therapeutics, Unit 601, University of Texas M.D. Anderson Cancer Center, 8000 El Rio, Houston, TX 77054, USA.

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http://dx.doi.org/10.1046/j.1359-4117.2003.01066.xDOI Listing
February 2004

Evaluation of in vitro drug interactions with karenitecin, a novel, highly lipophilic camptothecin derivative in phase II clinical development.

J Clin Pharmacol 2003 Sep;43(9):1008-14

Division of Pharmacy, University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Box 90, Houston, TX 77030, USA.

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http://dx.doi.org/10.1177/0091270003255921DOI Listing
September 2003

Subcellular localization and tumor-suppressive functions of 15-lipoxygenase 2 (15-LOX2) and its splice variants.

J Biol Chem 2003 Jul 18;278(27):25091-100. Epub 2003 Apr 18.

Department of Carcinogenesis, the University of Texas M. D. Anderson Cancer Center, Science Park Research Division, Smithville 78957, USA.

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http://dx.doi.org/10.1074/jbc.M301920200DOI Listing
July 2003

Inhibition of proliferation of PC3 cells by the branched-chain fatty acid, 12-methyltetradecanoic acid, is associated with inhibition of 5-lipoxygenase.

Prostate 2003 Jun;55(4):281-91

Department of Experimental Therapeutics, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77090-1009, USA.

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http://doi.wiley.com/10.1002/pros.10243
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http://dx.doi.org/10.1002/pros.10243DOI Listing
June 2003

Phase I and pharmacological study of oral 9-aminocamptothecin colloidal dispersion (NSC 603071) in patients with advanced solid tumors.

Clin Cancer Res 2003 Jun;9(6):2066-71

Department of Gastrointestinal Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.

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June 2003

Use of microdialysis to study platinum anticancer agent pharmacokinetics in preclinical models.

J Exp Ther Oncol 2002 May-Jun;2(3):163-73

Divisions of Pharmacy and Cancer Medicine, University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1046/j.1359-4117.2002.01019.xDOI Listing
March 2003

Murine pharmacokinetics and metabolism of oleandrin, a cytotoxic component of Nerium oleander.

J Exp Ther Oncol 2002 Sep-Oct;2(5):278-85

Pharmaceutical Development Center, University of Texas M.D. Anderson Cancer Center, 8000 El Rio, Houston, TX 77054, USA.

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http://dx.doi.org/10.1046/j.1359-4117.2002.01052.xDOI Listing
March 2003

Aberrant arachidonic acid metabolism in esophageal adenocarcinogenesis, and the effects of sulindac, nordihydroguaiaretic acid, and alpha-difluoromethylornithine on tumorigenesis in a rat surgical model.

Carcinogenesis 2002 Dec;23(12):2095-102

Susan Lehman Cullman Laboratory for Cancer Research, Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, State University of New Jersey, 164 Frelinghuysen Road, Piscataway 08854, USA.

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http://dx.doi.org/10.1093/carcin/23.12.2095DOI Listing
December 2002