Robert A Fowler

Robert A Fowler

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Temporal Variations in Incidence andOutcomes of Critical Illness Among Pregnant and Postpartum Women inCanada: A Population-Based Observational Study.

J Obstet Gynaecol Can 2019 May 29;41(5):631-640. Epub 2018 Oct 29.

Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON; Department of Critical Care Medicine, Sunnybrook Health Science Center, Toronto, ON.

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https://linkinghub.elsevier.com/retrieve/pii/S17012163183063
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http://dx.doi.org/10.1016/j.jogc.2018.07.021DOI Listing
May 2019

New filovirus disease classification and nomenclature.

Nat Rev Microbiol 2019 May;17(5):261-263

World Health Organization Regional Office for Africa, Brazzaville, Democratic Republic of the Congo.

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http://dx.doi.org/10.1038/s41579-019-0187-4DOI Listing
May 2019

Anti-Ebola therapy for patients with Ebola virus disease: a systematic review.

BMC Infect Dis 2019 May 2;19(1):376. Epub 2019 May 2.

Department of Critical Care Medicine, Sunnybrook Health Sciences Centre and Interdepartmental Division of Critical Care Medicine and Institute for Health Policy, Management, and Evaluation, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1186/s12879-019-3980-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498552PMC
May 2019

Challenging the Pessimism in Providing Critical Care for Elderly Patients.

JAMA Netw Open 2019 May 3;2(5):e193201. Epub 2019 May 3.

Sunnybrook Research Institute, Sunnybrook Hospital, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1001/jamanetworkopen.2019.3201DOI Listing
May 2019

Clinical spectrum of the Middle East respiratory syndrome coronavirus (MERS-CoV).

J Infect Public Health 2017 Mar - Apr;10(2):191-194. Epub 2016 Apr 29.

Institute of Health Policy Management and Evaluation, University of Toronto, Toronto, Canada; Department of Critical Care Medicine and Department of Medicine, Sunnybrook Health Sciences Center, Toronto, Canada.

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http://dx.doi.org/10.1016/j.jiph.2016.04.008DOI Listing
April 2019

Macrolides in critically ill patients with Middle East Respiratory Syndrome.

Int J Infect Dis 2019 Apr 25;81:184-190. Epub 2019 Jan 25.

International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC), Division of Infectious Diseases and International Health, Department of Medicine, University of Virginia School of Medicine, Charlottesville, VA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ijid.2019.01.041DOI Listing
April 2019

Trends in site of death and health care utilization at the end of life: a population-based cohort study.

CMAJ Open 2019 Apr-Jun;7(2):E306-E315. Epub 2019 Apr 26.

Departments of Critical Care Medicine (Hill, Scales, Rubenfeld, Wunsch, Dev, Fowler) and of Medicine (Gandhi, Berry), Sunnybrook Health Sciences Centre; Sunnybrook Research Institute (Hill); ICES (Stukel, Fu, Scales); Institute of Health Policy, Management and Evaluation (Stukel, Fowler), Interdepartmental Division of Critical Care (Scales, Rubenfeld, Wunsch, Dev, Fowler), Faculty of Medicine (Laupacis), Department of Anesthesia (Wunsch), Department of Medicine (Sinha, Gandhi, La Delfa), Division of Palliative Medicine, Department of Medicine (Zimmermann), and Division of Palliative Care, Department of Family Medicine, Faculty of Medicine (Myers), University of Toronto; Li Ka Shing Knowledge Institute (Laupacis) and Department of Palliative Care (La Delfa), St. Michael's Hospital, Toronto, Ont.; Departments of Medicine and Critical Care (Downar), Division of Palliative Care, University of Ottawa, Ottawa, Ont.; Divisions of Geriatric Medicine and Neurology (Rockwood), Department of Medicine, Dalhousie University, Halifax, NS; Department of Critical Care Medicine (Heyland), Queen's University, Kingston Ont.; Department of Medicine (Sinha) and Division of Palliative Care (Myers), Sinai Health System; Department of Medicine (Sinha), Division of Palliative Care, Department of Supportive Care (Zimmermann), and Ted Rogers Centre for Heart Research, Peter Munk Cardiac Centre (Ross), University Health Network, Toronto, Ont.; School of Population and Public Health (Kozak), University of British Columbia; Department of Family and Community Medicine (Kozak), Providence Health Care, Vancouver, BC.

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http://cmajopen.ca/lookup/doi/10.9778/cmajo.20180097
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http://dx.doi.org/10.9778/cmajo.20180097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488480PMC
April 2019

Noninvasive ventilation in critically ill patients with the Middle East respiratory syndrome.

Influenza Other Respir Viruses 2019 Mar 18. Epub 2019 Mar 18.

Intensive Care Department, King Abdullah International Medical Research Center, College of Medicine, King Abdulaziz Medical City, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.

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http://dx.doi.org/10.1111/irv.12635DOI Listing
March 2019

The evolution of supportive care for Ebola virus disease.

Lancet 2019 02 4;393(10172):620-621. Epub 2019 Feb 4.

University of Toronto, Toronto, ON, Canada; Sunnybrook Health Science Center, Toronto, ON, Canada.

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http://dx.doi.org/10.1016/S0140-6736(19)30242-9DOI Listing
February 2019

Rates of Mechanical Ventilation for Patients With Dementia in Ontario: A Population-Based Cohort Study.

Anesth Analg 2019 Jan 8. Epub 2019 Jan 8.

From the Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1213/ANE.0000000000004003DOI Listing
January 2019

Shortening Antibiotic Treatment Durations for Bacteremia.

Clin Infect Dis 2018 Dec 11. Epub 2018 Dec 11.

Department of Critical Care, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1093/cid/ciy1057DOI Listing
December 2018

Non-invasive ventilation in children and adults in low- and low-middle income countries: A systematic review and meta-analysis.

J Crit Care 2018 Oct 12;47:310-319. Epub 2018 Jan 12.

Department of Critical Care Medicine, Room D1.08, Sunnybrook Health Sciences Centre and University of Toronto, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08839441173024
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http://dx.doi.org/10.1016/j.jcrc.2018.01.007DOI Listing
October 2018

Gaps in the Clinical Management of Influenza: A Century Since the 1918 Pandemic.

JAMA 2018 Aug;320(8):755-756

Division of Pulmonary and Critical Care Medicine, University of North Carolina at Chapel Hill.

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http://dx.doi.org/10.1001/jama.2018.8113DOI Listing
August 2018

Patient, family and provider experiences with transfers from intensive care unit to hospital ward: a multicentre qualitative study.

CMAJ 2018 Jun;190(22):E669-E676

Alberta Health Services (Stelfox, Bagshaw); W21C Research and Innovation Centre (de Grood), O'Brien Institute for Public Health (Parsons Leigh, Stelfox), Department of Critical Care Medicine (Parsons Leigh, Stelfox, Boyd), and Department of Community Health Sciences (Parsons Leigh, Stelfox, de Grood), University of Calgary, Calgary, Alta.; Department of Critical Care Medicine (Bagshaw), Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alta.; Division of Critical Care Medicine and Centre for Health Evaluation and Outcome Sciences (Dodek), St. Paul's Hospital and University of British Columbia, Vancouver, BC; Departments of Medicine and Critical Care Medicine (Fowler), Sunnybrook Hospital, University of Toronto, Toronto, Ont.; Department of Medicine (Forster), The Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ont.

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http://dx.doi.org/10.1503/cmaj.170588DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988518PMC
June 2018

7 versus 14 days of antibiotic treatment for critically ill patients with bloodstream infection: a pilot randomized clinical trial.

Trials 2018 Feb 17;19(1):111. Epub 2018 Feb 17.

Departments of Medicine and Critical Care Medicine, Sunnybrook Health Sciences Center, Adjunct Scientist, Institute for Clinical Evaluative Sciences, Sunnybrook Health Sciences Centre, Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1186/s13063-018-2474-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816399PMC
February 2018

Measurement properties of comorbidity indices in maternal health research: a systematic review.

BMC Pregnancy Childbirth 2017 Nov 13;17(1):372. Epub 2017 Nov 13.

Department of Critical Care Medicine, Sunnybrook Health Science Centre, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1186/s12884-017-1558-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683518PMC
November 2017

Burn center care reduces acute health care utilization after discharge: A population-based analysis of 1,895 survivors of major burn injury.

Surgery 2017 10 13;162(4):891-900. Epub 2017 Jul 13.

Sunnybrook Research Institute, Toronto, Canada; Ross Tilley Burn Centre, Sunnybrook Health Sciences Centre, Toronto, Canada; Institute of Medical Sciences, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1016/j.surg.2017.05.018DOI Listing
October 2017

Association Between Burn Injury and Mental Illness among Burn Survivors: A Population-Based, Self-Matched, Longitudinal Cohort Study.

J Am Coll Surg 2017 Oct 31;225(4):516-524. Epub 2017 Jul 31.

Sunnybrook Research Institute, Toronto, Canada; Institute of Medical Sciences, University of Toronto, Toronto, Canada; Ross Tilley Burn Centre, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1016/j.jamcollsurg.2017.06.004DOI Listing
October 2017

Time required to initiate outbreak and pandemic observational research.

J Crit Care 2017 08 1;40:7-10. Epub 2017 Mar 1.

Departments of Medicine and Critical Care Medicine, Sunnybrook Health Sciences Center, Institute of Health Policy Management and Evaluation, University of Toronto, Toronto, Ontario, Canada M4N 3M5. Electronic address:

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http://dx.doi.org/10.1016/j.jcrc.2017.02.009DOI Listing
August 2017

Development of an intensive care unit resource assessment survey for the care of critically ill patients in resource-limited settings.

J Crit Care 2017 04 5;38:172-176. Epub 2016 Nov 5.

Interdepartmental Division of Critical Care, University of Toronto, Toronto, Canada; Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jcrc.2016.11.002DOI Listing
April 2017

Long-Term Outcomes and Health Care Utilization after Prolonged Mechanical Ventilation.

Ann Am Thorac Soc 2017 Mar;14(3):355-362

1 Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1513/AnnalsATS.201610-792OCDOI Listing
March 2017

Middle East Respiratory Syndrome.

N Engl J Med 2017 02;376(6):584-594

From the Departments of Intensive Care (Y.M.A., A. Bouchama), Infection Prevention and Control (H.H.B.), and Pathology and Laboratory (A.H.H.), King Abdulaziz Medical City, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center (Y.M.A., H.H.B., A. Bouchama, A.H.H.), the Department of Intensive Care, Dr. Sulaiman Al-Habib Group Hospitals (A.A.-O.), and Alfaisal University (A.A.-O.) - all in Riyadh, Saudi Arabia; the Department of Medicine, Division of Infectious Diseases and International Health, University of Virginia School of Medicine, Charlottesville (F.G.H.); the Department of Viral and Rickettsial Diseases, Naval Medical Research Center, Silver Spring, MD (T.L.); the Roslin Institute, University of Edinburgh, and Intensive Care Unit, Royal Infirmary of Edinburgh, Edinburgh (J.K.B.), the Health Protection and Influenza Research Group, Division of Epidemiology and Public Health, University of Nottingham, Nottingham (J.S.N.-V.-T.), and the Virus Reference Laboratory, Public Health England, London (A. Bermingham) - all in the United Kingdom; the Department of Pandemic and Epidemic Diseases, World Health Organization, Geneva (M.S., N.S., R.A.F.); the Department of Pediatrics, Vanderbilt University School of Medicine, Nashville (M.R.D., J.D.C.); the Center for Global Health, Institut Pasteur, Paris (M.D.V.K.); and the Institute of Health Policy Management and Evaluation, University of Toronto, and the Department of Critical Care Medicine and Department of Medicine, Sunnybrook Health Sciences Centre - both in Toronto (R.A.F.).

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http://dx.doi.org/10.1056/NEJMsr1408795DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362064PMC
February 2017

The search for therapeutic options for Middle East Respiratory Syndrome (MERS).

J Infect Public Health 2016 May-Jun;9(3):213-5. Epub 2016 Mar 31.

Institute of Health Policy Management and Evaluation, University of Toronto, Toronto, Canada; Department of Critical Care Medicine and Department of Medicine, Sunnybrook Health Sciences Centre, Toronto, Canada.

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http://dx.doi.org/10.1016/j.jiph.2016.03.004DOI Listing
January 2017

Patient and Organizational Factors Associated With Delays in Antimicrobial Therapy for Septic Shock.

Crit Care Med 2016 Dec;44(12):2145-2153

1Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.2Department of Emergency Medicine, University Health Network, University of Toronto, Toronto, ON, Canada.3Critical Care Medicine, Prairie Mountain Health, Brandon, MB, Canada.4Department of Surgery, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.5Critical Care Medicine, Richmond General Hospital, Richmond, BC, Canada.6Critical Care Medicine, Royal Columbian Hospital, New Westminster, BC, Canada.7Critical Care Medicine, Jewish General Hospital, Montreal, QC, Canada.8Critical Care Medicine and Department of Medicine, Winnipeg Regional Health Authority, Winnipeg, MB, Canada.

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http://dx.doi.org/10.1097/CCM.0000000000001868DOI Listing
December 2016

The Postcardiac Arrest Consult Team: Impact on Hospital Care Processes for Out-of-Hospital Cardiac Arrest Patients.

Crit Care Med 2016 Nov;44(11):2037-2044

1Department of Emergency Medicine, Queen's University, Kingston, ON, Canada. 2Rescu, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Ontario Canada. 3Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, Toronto, ON, Canada. 4Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada. 5Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON. 6Critical Care Department, St. Michael's Hospital, Toronto, ON, Canada. 7Department of Emergency Medicine, St. Michael's Hospital, Toronto, ON, Canada. 8Division of Emergency Medicine, Department of Medicine, University of Toronto, Toronto, ON, Canada. 9Heart and Vascular Program, St. Michael's Hospital, Toronto, ON, Canada. 10Division of Cardiology, Department of Medicine, University of Toronto, Toronto, ON, Canada. 11Department of Anesthesia, St. Michael's Hospital, Toronto, ON, Canada. 12Division of Cardiology, Schulich Heart Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1097/CCM.0000000000001863DOI Listing
November 2016

Does Sample Size Matter When Interpreting the Fragility Index?

Crit Care Med 2016 11;44(11):e1142-e1143

Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, Toronto, ON, Canada; Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, Toronto, ON, Canada, Department of Medicine, University of Toronto, Toronto, ON, Canada, Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada; Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, Toronto, ON, Canada, Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1097/CCM.0000000000001976DOI Listing
November 2016

Influenza A (H1N1pdm09)-Related Critical Illness and Mortality in Mexico and Canada, 2014.

Crit Care Med 2016 Oct;44(10):1861-70

1Department of Critical Care Medicine, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.2Escuela de Medicina, Tecnologico de Monterrey, Monterrey, Mexico.3Department of Hospital Epidemiology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.4Trauma, Emergency and Critical Care, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.5Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.6Department of Critical Care Medicine, Instituto Nacional de Cancerología, Mexico City, Mexico.7Department of Infectious Diseases, Hospital universitario Dr. José Eleuterio González, Monterrey, Nuevo León, Mexico.8Department of Critical Care Medicine and Emergency, Instituto de Salud del Estado de México, Toluca, Mexico.9Department of Critical Care Medicine, Instituto Nacional de Enfermedades Respiratorias, Mexico City, Mexico.10Department of Critical Care Medicine, Hospital General de Tijuana, Tijuana, Baja California, Mexico.11Department of Critical Care Medicine, Hospital Central Ignacio Morones Prieto, San Luis Potosi, Mexico.12Department of Critical Care Medicine, Hospital General de Uruapan, Uruapan, Michoacan, Mexico.13Department of Infectious Diseases, Hospital General Regional de León, León, Guanajuato, Mexico.14Department of Infectious Diseases, Hospital Regional de Alta Especialidad de Oaxaca, Oaxaca, Mexico.15Department of Critical Care Medicine, Hospital General "Dr. Manuel Gea González," Mexico City, Mexico.16Department of Disasters Response, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.17Department of Critical Care Medicine, Hospital San José Monterrey, Monterrey, Nuevo León, Mexico.18Faculty of Medicine, Universidad de Guanajuato, León, Guanajuato, Mexico.19Department of Critical Care Medicine, Hospital Regional de Alta Especialidad de Oaxaca,

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http://dx.doi.org/10.1097/CCM.0000000000001830DOI Listing
October 2016

Pathogens and antimicrobial susceptibility profiles in critically ill patients with bloodstream infections: a descriptive study.

CMAJ Open 2016 Oct-Dec;4(4):E569-E577. Epub 2016 Oct 13.

Dalla Lana School of Public Health (Savage), University of Toronto; Sunnybrook Health Sciences Centre (Savage, Fowler, Rishu, Daneman), Toronto, Ont.; Division of Critical Care Medicine (Fowler), Department of Medicine; Institute of Health Policy, Management and Evaluation (Fowler, Daneman), University of Toronto, Toronto, Ont.; Division of Critical Care Medicine (Bagshaw), Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alta.; Departments of Medicine and Clinical Epidemiology & Biostatistics (Cook), McMaster University, Hamilton, Ont.; Division of Critical Care Medicine (Dodek, Reynolds), Department of Medicine, University of British Columbia; Center for Health Evaluation and Outcome Sciences (Dodek), St. Paul's Hospital, Vancouver, BC; Department of Critical Care Medicine (Hall), Faculty of Medicine, Dalhousie University; Nova Scotia Health Authority (Hall), Halifax, NS; Section of Critical Care Medicine (Kumar), Department of Medicine; Departments of Medical Microbiology and of Pharmacology and Therapeutics (Kumar), University of Manitoba, Winnipeg, Man.; Centre de recherche du Centre hospitalier universitaire de Sherbrooke (Lamontagne), Sherbrooke, Que.; Service de médecine interne (Lamontagne), Département de médecine, Université de Sherbrooke, Sherbrooke, Que.; Axe Santé des populations et pratiques optimales en santé (Lauzier), Centre de recherche du Centre hospitalier universitaire de Québec-Université Laval, Québec, Que.; Départements de medicine et d'anesthésiologie et de soins intensifs (Lauzier), Université Laval, Québec, Que.; St. Michael's Hospital (Marshall), Toronto, Ont.; Department of Surgery (Marshall), University of Toronto, Toronto, Ont.; Department of Medicine (Martin), Western University; Critical Care Medicine (Martin), Schulich School of Medicine & Dentistry, London Health Sciences Centre, London, Ont.; Division of Critical Care (McIntyre), Department of Medicine, The Ottawa Hospital, Ottawa, Ont.; Department of Medicine (Muscedere), Queen's University, Kingston, Ont.; Department of Critical Care Medicine (Muscedere), Kingston General Hospital, Kingston, Ont.; Department of Critical Care Medicine (Stelfox), University of Calgary, Calgary, Alta.; Division of Infectious Diseases (Daneman), Department of Medicine, University of Toronto; Institute for Clinical Evaluative Sciences (Daneman), Toronto, Ont.

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http://dx.doi.org/10.9778/cmajo.20160074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173462PMC
October 2016

The authors reply.

Crit Care Med 2016 08;44(8):e776

Division of Infectious Diseases, Department of Medicine & Clinical Epidemiology, Sunnybrook Health Sciences Centre, University of Toronto and Adjunct Scientist, Toronto, ON, Canada, Institute for Clinical Evaluative Sciences, Sunnybrook Health Sciences Centre, Toronto, ON, Canada; Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, Toronto, ON, Canada; Department of Medicine and Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1097/CCM.0000000000001898DOI Listing
August 2016

Prevalence, risk factors, and outcomes associated with physical restraint use in mechanically ventilated adults.

J Crit Care 2016 Feb 25;31(1):31-5. Epub 2015 Sep 25.

University of Toronto, Toronto, ON, Canada; Department of Medicine and Interdepartmental Division of Critical Care Medicine, Mount Sinai Hospital, 600 University Ave, Toronto, ON, Canada, M5G 1X5. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08839441150047
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http://dx.doi.org/10.1016/j.jcrc.2015.09.011DOI Listing
February 2016

Duration of Antimicrobial Treatment for Bacteremia in Canadian Critically Ill Patients.

Crit Care Med 2016 Feb;44(2):256-64

1Division of Infectious Diseases, Department of Medicine and Clinical Epidemiology, Sunnybrook Health Sciences Centre, University of Toronto and Adjunct Scientist, Institute for Clinical Evaluative Sciences, Sunnybrook Health Sciences Centre, Toronto, ON, Canada. 2Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, Toronto, ON, Canada. 3Division of Critical Care Medicine, University of Alberta, Edmonton, AB, Canada. 4Division of Critical Care Medicine and Center for Health Evaluation and Outcome Sciences, St. Paul's Hospital and University of British Columbia, Vancouver, BC, Canada. 5Department of Critical Care Medicine, Dalhousie University and the Capital District, Health Authority, Halifax, NS, Canada. 6Sections of Critical Care Medicine and Infectious Diseases, University of Manitoba, Winnipeg, MB, Canada. 7Department of Medicine, Centre de recherche du CHU de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, Canada. 8Centre de recherche du CHU de Québec, Axe santé des populations et pratiques optimales en santé, Division de soins intensifs adultes, départements de médecine et d'anesthésiologie, Université Laval, Quebec, QC, Canada. 9Departments of Surgery and Critical Care Medicine, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada. 10Department of Medicine, University of Western Ontario, London, ON, Canada. 11Division of Critical Care, Department of Medicine, The Ottawa Hospital, Ottawa, ON, Canada. 12Department of Medicine, Queen's University, Kingston, ON, Canada. 13Department of Medicine, University of British Columbia, Vancouver, BC, Canada. 14Department of Critical Care Medicine, University of Calgary, Calgary, AB, Canada. 15Departments of Medicine, Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada. 16Department of Medicine and Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1097/CCM.0000000000001393DOI Listing
February 2016

Hospital Incidence and Outcomes of the Acute Respiratory Distress Syndrome Using the Kigali Modification of the Berlin Definition.

Am J Respir Crit Care Med 2016 Jan;193(1):52-9

7 Department of Critical Care Medicine and Department of Medicine, Sunnybrook Hospital, Interdepartmental Division of Critical Care, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1164/rccm.201503-0584OCDOI Listing
January 2016

Expanding the scope of Critical Care Rapid Response Teams: a feasible approach to identify adverse events. A prospective observational cohort.

BMJ Qual Saf 2015 Dec 8;24(12):764-8. Epub 2015 Jun 8.

Interdepartmental Division of Critical Care, University of Toronto, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1136/bmjqs-2014-003833DOI Listing
December 2015

The challenges of treating Ebola virus disease with experimental therapies.

Lancet Respir Med 2015 Jul;3(7):503-4

Department of Medicine and Interdepartmental Division of Critical Care Medicine, University of Toronto, Sunnybrook Hospital, Bayview Avenue, Toronto, ON M4N 3M5, Canada. Electronic address:

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http://dx.doi.org/10.1016/S2213-2600(15)00237-4DOI Listing
July 2015

Economic Evaluations in the Diagnosis and Management of Traumatic Brain Injury: A Systematic Review and Analysis of Quality.

Value Health 2015 Jul 26;18(5):721-34. Epub 2015 Jul 26.

Sunnybrook Research Institute, Sunnybrook Health Sciences Center, Toronto, ON, Canada; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada; Keenan Research Centre of the Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, ON, Canada; Department of Surgery, Sunnybrook Health Sciences Center, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1016/j.jval.2015.04.012DOI Listing
July 2015

Global participation in core data sets for emerging pathogens.

Am J Respir Crit Care Med 2015 Apr;191(7):728-30

1 University of North Carolina Chapel Hill, North Carolina.

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http://dx.doi.org/10.1164/rccm.201412-2272EDDOI Listing
April 2015

Prolonged mechanical ventilation in Canadian intensive care units: a national survey.

J Crit Care 2015 Feb 31;30(1):25-31. Epub 2014 Jul 31.

Sunnybrook Research Institute, Toronto, Ontario, Canada M4N 3M5; Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Ontario, Canada, M5G 2C4; Trauma, Emergency, and Critical Care Program, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada M4N 3M5. Electronic address:

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http://search.proquest.com/openview/a4da6a13c24cbef4489f12b7
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http://linkinghub.elsevier.com/retrieve/pii/S088394411400312
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http://dx.doi.org/10.1016/j.jcrc.2014.07.023DOI Listing
February 2015

Ebola care and research protocols.

Intensive Care Med 2015 Jan 27;41(1):111-4. Epub 2014 Nov 27.

Department of Intensive Care, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark,

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http://dx.doi.org/10.1007/s00134-014-3568-1DOI Listing
January 2015

Understanding organ dysfunction in Ebola virus disease.

Intensive Care Med 2014 Dec 1;40(12):1936-9. Epub 2014 Nov 1.

WellcomeTraining Fellow and Lecturer, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3 5QA, UK,

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http://link.springer.com/10.1007/s00134-014-3515-1
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http://dx.doi.org/10.1007/s00134-014-3515-1DOI Listing
December 2014

Impact of acute stress on resident performance during simulated resuscitation episodes: a prospective randomized cross-over study.

Teach Learn Med 2014 ;26(1):9-16

a Department of Critical Care Medicine , University of Toronto , Toronto , Ontario , Canada.

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http://dx.doi.org/10.1080/10401334.2014.859932DOI Listing
October 2014

Economic evaluation of decompressive craniectomy versus barbiturate coma for refractory intracranial hypertension following traumatic brain injury.

Crit Care Med 2014 Oct;42(10):2235-43

1Sunnybrook Research Institute, Sunnybrook Health Sciences Center, Toronto, ON, Canada. 2Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada. 3Division of Neurosurgery, University of Ottawa, Ottawa, ON, Canada. 4Department of Medicine, University of Toronto, Toronto, ON, Canada. 5Division of Neurosurgery, University of Toronto, Toronto, ON, Canada. 6Department of Critical Care, Sunnybrook Health Sciences Center, Toronto, ON, Canada. 7Interdepartmental Division of Critical Care, University of Toronto, Toronto, ON, Canada. 8Keenan Research Centre of the Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada. 9Department of Surgery, Sunnybrook Health Sciences Center, University of Toronto, Toronto, ON, Canada.

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October 2014

Age-related trends in severe injury hospitalization in Canada.

J Trauma Acute Care Surg 2014 Oct;77(4):608-13

From Sunnybrook Research Institute (A.D.H., A.B.N., R.A.F.); Departments of Critical Care (A.D.H., R.A.F., R.P.), and Surgery (A.B.N.), Sunnybrook Health Sciences Centre; Clinical Epidemiology Program (R.A.F., A.B.N.), Institute of Health Policy, Management and Evaluation, and Interdepartmental Division of Critical Care (R.A.F.), and Keenan Research Centre of the Li Ka Shing Knowledge Institute (A.B.N), St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.

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October 2014

Doing today's work superbly well--treating Ebola with current tools.

N Engl J Med 2014 Oct 24;371(17):1565-6. Epub 2014 Sep 24.

From the Centre de Recherche Clinique, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, QC, Canada (F.L.); Réanimation Médicale, Polyclinique Bordeaux Nord Aquitaine, Bordeaux, France (C.C.); Liverpool School of Tropical Medicine, Liverpool, United Kingdom (T.F.); University of Washington, Seattle (S.T.J.); University of North Carolina at Chapel Hill, Chapel Hill (W.A.F.); and University of Toronto, Toronto (R.A.F.).

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October 2014

Acute respiratory distress syndrome in the global context.

Glob Heart 2014 Sep 31;9(3):289-95. Epub 2014 Oct 31.

Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA; Department of Medicine, University of Rwanda, College of Medicine and Health Sciences, Kigali, Rwanda. Electronic address:

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September 2014

Tracheostomy timing in traumatic brain injury: a propensity-matched cohort study.

J Trauma Acute Care Surg 2014 Jan;76(1):70-6; discussion 76-8

From the Sunnybrook Research Institute (A.S.A., D.C.S., R.A.F., A.K., C.D.M., A.B.N.), Department of Critical Care (D.C.S., R.A.F.), Division of Neurosurgery (T.G.M.), Department of Research Design and Biostatistics (A.K.), and Department of Surgery (A.B.N.), Sunnybrook Health Sciences Center; Clinical Epidemiology Program (A.S.A., D.C.S., R.A.F., J.G.R., A.K., A.B.N.), Institute of Health Policy, Management and Evaluation, Interdepartmental Division of Critical Care (D.C.S., R.A.F.), and Keenan Research Centre of the Li Ka Shing Knowledge Institute (J.G.R, A.B.N) and Department of Medicine (J.G.R.), St. Michael's Hospital, University of Toronto, Toronto; and Division of Neurosurgery (A.S.A.), University of Ottawa, Ottawa, Ontario, Canada.

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January 2014

Duration of antibiotic therapy for critically ill patients with bloodstream infections: A retrospective cohort study.

Can J Infect Dis Med Microbiol 2013 ;24(3):129-37

Department of Medicine, University of Toronto, Toronto, Ontario ; Trauma, Emergency and Critical Care Research Program, Sunnybrook Research Institute, University of Toronto, Toronto, Ontario ; Division of Infectious Diseases, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852449PMC
January 2014

Effects of clinical supervision on resident learning and patient care during simulated ICU scenarios.

Crit Care Med 2013 Dec;41(12):2705-11

1Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada. 2Interdepartmental Division of Critical Care, University of Toronto, Toronto, ON, Canada. 3Wilson Centre for Research in Education, University of Toronto, Toronto, ON, Canada. 4Department of Anesthesia, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada. 5Faculty of Medicine, Centre for Health Education Scholarship, University of British Columbia, Vancouver, BC, Canada.

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December 2013

Infection prevention and control in the intensive care unit: open versus closed models of care.

Infect Control Hosp Epidemiol 2013 Aug 27;34(8):867-71. Epub 2013 Jun 27.

Division of Infectious Diseases, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.

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August 2013

Duration of antibiotic therapy for bacteremia: a systematic review and meta-analysis.

Crit Care 2011 15;15(6):R267. Epub 2011 Nov 15.

Department of Medicine, University of Toronto, 1 Kings College Circle, O, M5S 1A8, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388653PMC
June 2013

Acute kidney injury among critically ill patients with pandemic H1N1 influenza A in Canada: cohort study.

BMC Nephrol 2013 Jun 13;14:123. Epub 2013 Jun 13.

Division of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, 3C1.12 Walter C Mackenzie Centre, 8440-112 St NW, Edmonton, AB T6G 2B7, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694036PMC
June 2013

Effect of selective decontamination on antimicrobial resistance in intensive care units: a systematic review and meta-analysis.

Lancet Infect Dis 2013 Apr 25;13(4):328-41. Epub 2013 Jan 25.

Trauma, Emergency, and Critical Care Program, Sunnybrook Health Sciences Centre, University of Toronto, ON, Canada.

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April 2013

Clinical and temporal patterns of severe pneumonia causing critical illness during Hajj.

BMC Infect Dis 2012 May 16;12:117. Epub 2012 May 16.

Department of Intensive Care, Riyadh Military Hospital, P.O. Box 789711159, Riyadh, Kingdom of Saudi Arabia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458962PMC
May 2012

Economic analyses of venous thromboembolism prevention strategies in hospitalized patients: a systematic review.

Crit Care 2012 Mar 9;16(2):R43. Epub 2012 Mar 9.

Department of Medicine, St. Joseph's Hospital and McMaster University, Hamilton, Ontario, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964799PMC
March 2012

Critical care resources in the Solomon Islands: a cross-sectional survey.

BMC Int Health Hum Rights 2012 Mar 1;12. Epub 2012 Mar 1.

George Institute for Global Health, PO Box M201, Missenden Road Sydney, NSW 2050, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307438PMC
March 2012

Utility and safety of draining pleural effusions in mechanically ventilated patients: a systematic review and meta-analysis.

Crit Care 2011 2;15(1):R46. Epub 2011 Feb 2.

Interdepartmental Division of Critical Care, Mount Sinai Hospital and the University Health Network, University of Toronto, 600 University Avenue, Toronto, Ontario M5G 1X5, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221976PMC
December 2011

Impact of interhospital transfer on outcomes for trauma patients: a systematic review.

J Trauma 2011 Dec;71(6):1885-900; discussion 1901

Department of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada.

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December 2011

Patient and healthcare professional factors influencing end-of-life decision-making during critical illness: a systematic review.

Crit Care Med 2011 May;39(5):1174-89

Division of General Internal Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada.

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May 2011

A multifaceted intervention for quality improvement in a network of intensive care units: a cluster randomized trial.

JAMA 2011 Jan 19;305(4):363-72. Epub 2011 Jan 19.

Interdepartmental Division of Critical Care, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1001/jama.2010.2000DOI Listing
January 2011

Paediatric mortality related to H1N1 infection in England.

Lancet 2010 Nov 26;376(9755):1808-10. Epub 2010 Oct 26.

Department of Critical Care and Department of Medicine, Sunnybrook Hospital, University of Toronto, Toronto, ON, Canada M4N 3M5.

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November 2010