Robert A Anders

Robert A Anders

UNVERIFIED PROFILE

Are you Robert A Anders?   Register this Author

Register author
Robert A Anders

Robert A Anders

Publications by authors named "Robert A Anders"

Are you Robert A Anders?   Register this Author

100Publications

3776Reads

12Profile Views

Clinicopathological Distinction of Low-AFP-Secreting vs. High-AFP-Secreting Hepatocellular Carcinomas.

Ann Hepatol 2018 Nov - Dec;17(6):1052-1066

Johns Hopkins University School of Medicine, Division of Gastroenterology and Hepatology-Transplant Hepatology, Baltimore, MD, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5604/01.3001.0012.7206DOI Listing
November 2019

The number of microspheres in Y90 radioembolization directly affects normal tissue radiation exposure.

Eur J Nucl Med Mol Imaging 2019 Nov 18. Epub 2019 Nov 18.

Department of Radiology, Division of Vascular and Interventional Radiology, The Johns Hopkins Hospital, Baltimore, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00259-019-04588-xDOI Listing
November 2019

Axon Guidance Molecules Promote Perineural Invasion and Metastasis of Orthotopic Pancreatic Tumors in Mice.

Gastroenterology 2019 09 1;157(3):838-850.e6. Epub 2019 Jun 1.

Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland; Pancreatic Cancer Precision Medicine Program, Johns Hopkins University School of Medicine, Baltimore, Maryland; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland; Skip Viragh Center for Pancreatic Cancer, Johns Hopkins University School of Medicine, Baltimore, Maryland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.gastro.2019.05.065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707836PMC
September 2019

Multiple Immune-Suppressive Mechanisms in Fibrolamellar Carcinoma.

Cancer Immunol Res 2019 May 22;7(5):805-812. Epub 2019 Mar 22.

Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/2326-6066.CIR-18-0499DOI Listing
May 2019

Human colon mucosal biofilms from healthy or colon cancer hosts are carcinogenic.

J Clin Invest 2019 Mar 11;130:1699-1712. Epub 2019 Mar 11.

Bloomberg-Kimmel Institute for Immunotherapy, Departments of Oncology and Medicine and the Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1172/JCI124196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436866PMC
March 2019

Quantitative Characterization of CD8+ T Cell Clustering and Spatial Heterogeneity in Solid Tumors.

Front Oncol 2018 7;8:649. Epub 2019 Jan 7.

Department of Biomedical Engineering, School of Medicine, Johns Hopkins University, Baltimore, MD, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fonc.2018.00649DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330341PMC
January 2019

Bariatric Arterial Embolization: Effect of Microsphere Size on the Suppression of Fundal Ghrelin Expression and Weight Change in a Swine Model.

Radiology 2018 10 10;289(1):83-89. Epub 2018 Jul 10.

From the Russell H. Morgan Department of Radiology and Radiological Science (Y.F., C.R.W., K.P., D.K., D.L.K.), Department of Gastroenterology (E.J.S.), and Department of Pathology (R.A.A.), the Johns Hopkins University School of Medicine, 1800 Orleans St, Zayed Tower 7203, Baltimore, MD 21287; and Department of Radiology, Piedmont Healthcare, Atlanta, Ga (A.A.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1148/radiol.2018172874DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166770PMC
October 2018

Impact of histological subtype on the prognosis of patients undergoing surgery for colon cancer.

J Surg Oncol 2018 Jun 25;117(7):1355-1363. Epub 2018 Mar 25.

Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, Ohio.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jso.25044DOI Listing
June 2018

Combining intratumoral Treg depletion with androgen deprivation therapy (ADT): preclinical activity in the Myc-CaP model.

Prostate Cancer Prostatic Dis 2018 04 4;21(1):113-125. Epub 2017 Dec 4.

Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41391-017-0013-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897134PMC
April 2018

Liver Transplantation for Severe Alcoholic Hepatitis, Updated Lessons from the World's Largest Series.

J Am Coll Surg 2018 04 2;226(4):549-557. Epub 2018 Feb 2.

Department of Surgery, Johns Hopkins School of Medicine, Baltimore, MD. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jamcollsurg.2017.12.044DOI Listing
April 2018

Distinction of intrahepatic metastasis from multicentric carcinogenesis in multifocal hepatocellular carcinoma using molecular alterations.

Hum Pathol 2018 02 24;72:127-134. Epub 2017 Nov 24.

Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA; Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.humpath.2017.11.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435273PMC
February 2018

Implications of the tumor immune microenvironment for staging and therapeutics.

Mod Pathol 2018 02 1;31(2):214-234. Epub 2017 Dec 1.

Department of Pathology, The Johns Hopkins University SOM and Bloomberg-Kimmel Institute for Immunotherapy, Baltimore, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/modpathol.2017.156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132263PMC
February 2018

Immune checkpoint inhibitor colitis: the flip side of the wonder drugs.

Virchows Arch 2018 Jan 15;472(1):125-133. Epub 2017 Nov 15.

Johns Hopkins Medical Institutions, Baltimore, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00428-017-2267-zDOI Listing
January 2018

Characterization of the Immune Microenvironment in Hepatocellular Carcinoma.

Clin Cancer Res 2017 Dec 19;23(23):7333-7339. Epub 2017 Sep 19.

The Bloomberg-Kimmel Institute for Cancer Immunotherapy at Johns Hopkins, Baltimore, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-17-0950DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881396PMC
December 2017

Dual Inhibition of Hedgehog and c-Met Pathways for Pancreatic Cancer Treatment.

Mol Cancer Ther 2017 11 1;16(11):2399-2409. Epub 2017 Sep 1.

The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins Univer- sity School of Medicine, Baltimore, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1535-7163.MCT-16-0452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5670001PMC
November 2017

Derivation of a disease-specific human induced pluripotent stem cell line from a biliary atresia patient.

Stem Cell Res 2017 10 8;24:25-28. Epub 2017 Aug 8.

Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, USA; Cellular and Molecular Medicine Graduate Program, Johns Hopkins University School of Medicine, USA; Institute for Cell Engineering, Johns Hopkins University School of Medicine, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.scr.2017.08.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881114PMC
October 2017

Melanoma subtypes demonstrate distinct PD-L1 expression profiles.

Lab Invest 2017 09 24;97(9):1063-1071. Epub 2017 Jul 24.

Department of Dermatology, Johns Hopkins University School of Medicine, Bloomberg Kimmel Institute for Cancer Immunotherapy, and Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/labinvest.2017.64DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685163PMC
September 2017

PD-L1 Expression in Melanoma: A Quantitative Immunohistochemical Antibody Comparison.

Clin Cancer Res 2017 Aug 20;23(16):4938-4944. Epub 2017 Apr 20.

Department of Dermatology, Johns Hopkins University and the Bloomberg Kimmel Institute for Cancer Immunotherapy, Baltimore, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-16-1821DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175606PMC
August 2017

Circulating Tumor Cell Phenotype Predicts Recurrence and Survival in Pancreatic Adenocarcinoma.

Ann Surg 2016 Dec;264(6):1073-1081

*Department of Surgery, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University School of Medicine, Baltimore, MD†Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University School of Medicine, Baltimore, MD‡Department of Medical Oncology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University School of Medicine, Baltimore, MD§Department of Radiation Oncology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University School of Medicine, Baltimore, MD¶Department of Gastroenterology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University School of Medicine, Baltimore, MD||Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/SLA.0000000000001600DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936958PMC
December 2016

Key Histopathologic Features of Liver Biopsies That Distinguish Biliary Atresia From Other Causes of Infantile Cholestasis and Their Correlation With Outcome: A Multicenter Study.

Am J Surg Pathol 2016 12;40(12):1601-1615

*Department of Pathology and Laboratory Medicine, the Children's Hospital of Philadelphia, Philadelphia, PA ¶¶Department of Pathology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA Departments of †Surgery §§§Biostatistics, University of Michigan, Ann Arbor, MI ‡Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD §Division of Pediatric Pathology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH ¶Department of Pathology, Indiana University School of Medicine, Indianapolis, IN #Department of Pathology, Texas Children's Hospital, Houston, TX **Department of Pathology, Seattle Children's Hospital, Seattle, WA ††Department of Pathology, University of California San Francisco, San Francisco, CA ***Department of Pathology, Children's Hospital Los Angeles, Los Angeles, CA ‡‡Department of Pathology, Children's Hospital Colorado, Aurora, CO §§Department of Pathology, Kravis Children's Hospital, Mount Sinai Health System, New York, NY ∥∥Department of Pathology, Ann & Robert H. Lurie Children's Hospital, Chicago, IL ##Department of Pathology, Children's Healthcare of Atlanta, Atlanta, GA †††Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO ‡‡‡Quest Diagnostics, Health Informatics, Madison, NJ ∥Division of Pathology, The Hospital of Sick Children, Toronto, ON, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/PAS.0000000000000755DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123664PMC
December 2016

Microvascular Invasion in Hepatocellular Carcinoma and Liver Transplant.

Exp Clin Transplant 2016 Nov;14(Suppl 3):14-18

From the Division of Gastroenterology and Hepatology-Transplant Hepatology, the Johns Hopkins University School of Medicine, Baltimore, Maryland, United States.

View Article

Download full-text PDF

Source
November 2016

Fulminant Myocarditis with Combination Immune Checkpoint Blockade.

N Engl J Med 2016 Nov;375(18):1749-1755

From the Departments of Medicine (D.B.J., J.M.B., M.H., I.P., M.R.A., T.L.B., J.R.B., D.A.S., E.J.P., M.A.P., D.M.R., J.A.S., J.J.M.), Cancer Biology (J.M.B., J.J.M.), Pathology, Microbiology, and Immunology (M.L.C., L.C.-O., R.D.H.), Biostatistics (Y.X.), Pharmacology (D.M.R.), and Biomedical Informatics (Y.X., D.M.R.), the Cardio-oncology Program (D.A.S., J.J.M.), the Breast Cancer Research Program (J.M.B.), and the Center for Quantitative Sciences (Y.X.), Vanderbilt University Medical Center, Nashville; the Department of Medicine (S.C.) and the Division of Neuroimmunology (S.C., I.J.K.), Beth Israel Deaconess Medical Center, the Departments of Medicine (B.A.O., C.E.S., J.G.S.) and Pathology (A.H.L.), Brigham and Women's Hospital, the Department of Genetics, Harvard Medical School (J.G., C.E.S., J.G.S.) - all in Boston; Howard Hughes Medical Institute, Chevy Chase, MD (C.E.S.); Bristol-Myers Squibb, New York (N.K., G.P., D.S.R., J.S.D.); Neon Therapeutics, Cambridge, MA (R.P.D.); and the Departments of Pathology (J.M.T., R.A.A.), Dermatology (J.M.T.), and Oncology (L.A.D.), Johns Hopkins University, Baltimore.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMoa1609214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247797PMC
November 2016

Association of PD-1/PD-L axis expression with cytolytic activity, mutational load, and prognosis in melanoma and other solid tumors.

Proc Natl Acad Sci U S A 2016 11 11;113(48):E7769-E7777. Epub 2016 Nov 11.

Department of Oncology, The Johns Hopkins University School of Medicine, Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD 21287;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1607836113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137776PMC
November 2016

Yes-associated protein impacts adherens junction assembly through regulating actin cytoskeleton organization.

Am J Physiol Gastrointest Liver Physiol 2016 09 26;311(3):G396-411. Epub 2016 May 26.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajpgi.00027.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5076009PMC
September 2016

Somatically Acquired LINE-1 Insertions in Normal Esophagus Undergo Clonal Expansion in Esophageal Squamous Cell Carcinoma.

Hum Mutat 2016 09 13;37(9):942-54. Epub 2016 Jul 13.

McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/humu.23027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548391PMC
September 2016

Cancer-Associated Fibroblasts in Pancreatic Cancer Are Reprogrammed by Tumor-Induced Alterations in Genomic DNA Methylation.

Cancer Res 2016 09 5;76(18):5395-404. Epub 2016 Aug 5.

Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland. The Sidney Kimmel Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland. The Skip Viragh Center for Pancreatic Cancer Research and Clinical Care, Johns Hopkins University School of Medicine, Baltimore, Maryland. Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland. The Sol Goldman Pancreatic Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-15-3264DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026619PMC
September 2016

Emerging role of Hpo signaling and YAP in hepatocellular carcinoma.

J Hepatocell Carcinoma 2015 18;2:69-78. Epub 2015 Jun 18.

Department of Pathology, Sidney Kimmel Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2147/JHC.S48505DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918286PMC
August 2016

Program Death 1 Immune Checkpoint and Tumor Microenvironment: Implications for Patients With Intrahepatic Cholangiocarcinoma.

Ann Surg Oncol 2016 08 24;23(8):2610-7. Epub 2016 Mar 24.

Department of Surgery, John Hopkins University School of Medicine, Baltimore, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1245/s10434-016-5101-yDOI Listing
August 2016

Mechanism-driven biomarkers to guide immune checkpoint blockade in cancer therapy.

Nat Rev Cancer 2016 05 15;16(5):275-87. Epub 2016 Apr 15.

Department of Oncology, Johns Hopkins University School of Medicine, Sidney Kimmel Comprehensive Cancer Center and Bloomberg-Kimmel Institute for Cancer Immunotherapy, 1550 Orleans Street, CRB2 Room 508, Baltimore, Maryland 21287, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrc.2016.36DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381938PMC
May 2016

Magnetoencapsulated human islets xenotransplanted into swine: a comparison of different transplantation sites.

Xenotransplantation 2016 05 26;23(3):211-21. Epub 2016 May 26.

Interventional Radiology Center, Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/xen.12235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027196PMC
May 2016

Rotavirus Infects Human Biliary Epithelial Cells and Stimulates Secretion of Cytokines IL-6 and IL-8 via MAPK Pathway.

Biomed Res Int 2015 13;2015:697238. Epub 2015 Jul 13.

Pediatric Liver Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2015/697238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515493PMC
April 2016

Ganetespib radiosensitization for liver cancer therapy.

Cancer Biol Ther 2016 04;17(4):457-66

a Department of Radiation Oncology and Molecular Radiation Sciences , Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine , Baltimore , MD , USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/15384047.2016.1156258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910914PMC
April 2016

PD-L1 Expression as a Predictive Biomarker: Is Absence of Proof the Same as Proof of Absence?

JAMA Oncol 2016 Jan;2(1):54-5

Department of Pathology, Johns Hopkins University, Baltimore, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jamaoncol.2015.3782DOI Listing
January 2016

A polymeric nanoparticle formulation of curcumin in combination with sorafenib synergistically inhibits tumor growth and metastasis in an orthotopic model of human hepatocellular carcinoma.

Biochem Biophys Res Commun 2015 Dec 19;468(4):525-32. Epub 2015 Oct 19.

Department of Liver Surgery, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Shanghai, 200032, PR China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbrc.2015.10.031DOI Listing
December 2015

Yes-associated protein in the liver: Regulation of hepatic development, repair, cell fate determination and tumorigenesis.

Dig Liver Dis 2015 Oct 22;47(10):826-35. Epub 2015 May 22.

Research, Central Texas Veterans Health Care System, Temple, TX, United States; Digestive Diseases Research Center, BaylorScott&White Healthcare, Temple, TX, United States; Department of Internal Medicine and Medical Physiology, Texas A&M Health Science Center, Temple, TX, United States. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.dld.2015.05.011DOI Listing
October 2015

Hepatopulmonary syndrome is a frequent cause of dyspnea in the short telomere disorders.

Chest 2015 Oct;148(4):1019-1026

Department of Oncology, Baltimore, MD; Department of Pathology, Baltimore, MD; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1378/chest.15-0825DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594621PMC
October 2015

LINE-1 expression and retrotransposition in Barrett's esophagus and esophageal carcinoma.

Proc Natl Acad Sci U S A 2015 Sep 17;112(35):E4894-900. Epub 2015 Aug 17.

McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1502474112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568228PMC
September 2015

Semaphorin 3D autocrine signaling mediates the metastatic role of annexin A2 in pancreatic cancer.

Sci Signal 2015 Aug 4;8(388):ra77. Epub 2015 Aug 4.

Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. Graduate Program in Cellular and Molecular Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. Skip Viragh Center for Pancreatic Cancer, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/scisignal.aaa5823DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811025PMC
August 2015

β-Catenin destruction complex-independent regulation of Hippo-YAP signaling by APC in intestinal tumorigenesis.

Genes Dev 2015 Jul 20;29(14):1493-506. Epub 2015 Jul 20.

Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gad.264515.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526734PMC
July 2015

PD-1 Blockade in Tumors with Mismatch-Repair Deficiency.

N Engl J Med 2015 Jun 30;372(26):2509-20. Epub 2015 May 30.

From the Swim Across America Laboratory (D.T.L., J.N.U., B.R.B., L.A.D.), Sidney Kimmel Comprehensive Cancer Center (D.T.L., J.N.U., H.W., H.K., A.D.E., A.D.S., B.S.L., N.S.A., D.L., B.B., R.C.D., D.M.P., N.P., K.W.K., S.Z., B.V., L.A.D.), Ludwig Center and Howard Hughes Medical Institute (B.R.B., A.D.S., N.P., K.W.K., S.Z., B.V., L.A.D.), and the Departments of Radiology (A.Z.) and Pathology (F.B., T.H., R.H.H., L.D.W., N.C., T.C.C., J.M.T., R.A.A., J.R.E.), Johns Hopkins University School of Medicine, Baltimore; Department of Medicine, Stanford University School of Medicine, Stanford, CA (G.A.F.); Providence Cancer Center at Providence Health and Services, Portland, OR (T.S.C.); Department of Medicine, University of Pittsburgh Cancer Institute, University of Pittsburgh School of Medicine, Pittsburgh (J.J.L.); Bon Secours Cancer Institute, Richmond, VA (S.M.D.); Division of Medical Oncology, Ohio State University Comprehensive Cancer Center-James Cancer Center and Solove Research Institute, and Human Cancer Genetics Program, Ohio State University Comprehensive Cancer Center, Columbus (R.M.G., A.C.); and Merck, Kenilworth, NJ, and North Wales, PA (M.K.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMoa1500596DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481136PMC
June 2015

Homeostatic control of Hippo signaling activity revealed by an endogenous activating mutation in YAP.

Genes Dev 2015 Jun;29(12):1285-97

Howard Hughes Medical Institute, Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gad.264234.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495399PMC
June 2015

The prognostic value of stroma in pancreatic cancer in patients receiving adjuvant therapy.

HPB (Oxford) 2015 Apr 23;17(4):292-8. Epub 2014 Sep 23.

Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Sidney Kimmel Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/hpb.12334DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368391PMC
April 2015

PD-L1 expression in melanocytic lesions does not correlate with the BRAF V600E mutation.

Cancer Immunol Res 2015 Feb 4;3(2):110-5. Epub 2014 Nov 4.

Department of Pathology, The Johns Hopkins University School of Medicine and Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland. Department of Dermatology, The Johns Hopkins University School of Medicine and Sidney Kimmel Comprehensive Cancer Center, Baltimore, Baltimore, Maryland. Department of Oncology, The Johns Hopkins University School of Medicine and Sidney Kimmel Comprehensive Cancer Center, Baltimore, Baltimore, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/2326-6066.CIR-14-0145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324161PMC
February 2015

Pharmacological activation of myosin II paralogs to correct cell mechanics defects.

Proc Natl Acad Sci U S A 2015 Feb 20;112(5):1428-33. Epub 2015 Jan 20.

Departments of Cell Biology, Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205; Department of Chemical and Biomolecular Engineering, Whiting School of Engineering, Johns Hopkins University, Baltimore, MD 21218; and

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1412592112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321244PMC
February 2015

PD-1/PD-L1 blockade together with vaccine therapy facilitates effector T-cell infiltration into pancreatic tumors.

J Immunother 2015 Jan;38(1):1-11

Departments of *Oncology #Pathology †Surgery ‡The Sidney Kimmel Cancer Center §The Skip Viragh Center for Pancreatic Cancer Research and Clinical Care ∥The Sol Goldman Pancreatic Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD ¶Amplimmune Inc., Gaithersburg, MD **Department of Surgery, University of Colorado School of Medicine, Aurora, CO.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/CJI.0000000000000062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258151PMC
January 2015

Immunotherapy converts nonimmunogenic pancreatic tumors into immunogenic foci of immune regulation.

Cancer Immunol Res 2014 Jul 18;2(7):616-31. Epub 2014 Jun 18.

Authors' Affiliations: Departments of Oncology, Surgery; The Sidney Kimmel Cancer Center; The Skip Viragh Center for Pancreatic Cancer Research and Clinical Care; The Sol Goldman Pancreatic Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland; and

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/2326-6066.CIR-14-0027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082460PMC
July 2014

The use of Yes-associated protein expression in the diagnosis of persistent neonatal cholestatic liver disease.

Hum Pathol 2014 May 23;45(5):1057-64. Epub 2014 Jan 23.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.humpath.2014.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151519PMC
May 2014

Treatment and prognosis of patients with fibrolamellar hepatocellular carcinoma: a national perspective.

J Am Coll Surg 2014 Feb 24;218(2):196-205. Epub 2013 Oct 24.

Department of Surgery, Johns Hopkins Hospital, Baltimore, MD. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jamcollsurg.2013.10.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596238PMC
February 2014

Induction of innate lymphoid cell-derived interleukin-22 by the transcription factor STAT3 mediates protection against intestinal infection.

Immunity 2014 Jan 9;40(1):25-39. Epub 2014 Jan 9.

Department of Pathology and Committee on Immunology, The University of Chicago, Chicago, IL 60637, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.immuni.2013.10.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919552PMC
January 2014

Durable cancer regression off-treatment and effective reinduction therapy with an anti-PD-1 antibody.

Clin Cancer Res 2013 Jan 20;19(2):462-8. Epub 2012 Nov 20.

Department of Oncology, Johns Hopkins University School of Medicine and Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD 21287, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-12-2625DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548952PMC
January 2013

Immunohistochemical staining of B7-H1 (PD-L1) on paraffin-embedded slides of pancreatic adenocarcinoma tissue.

J Vis Exp 2013 Jan 3(71). Epub 2013 Jan 3.

The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3791/4059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582653PMC
January 2013

Expression of Yes-associated protein modulates Survivin expression in primary liver malignancies.

Hum Pathol 2012 Sep 19;43(9):1376-85. Epub 2012 Mar 19.

Department of Pathology, Howard Hughes Medical Institute Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.humpath.2011.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384990PMC
September 2012

Yes-associated protein regulates the hepatic response after bile duct ligation.

Hepatology 2012 Sep 8;56(3):1097-107. Epub 2012 Aug 8.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hep.25769DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431197PMC
September 2012

Polymeric nanoparticle-encapsulated hedgehog pathway inhibitor HPI-1 (NanoHHI) inhibits systemic metastases in an orthotopic model of human hepatocellular carcinoma.

Clin Cancer Res 2012 Mar 25;18(5):1291-302. Epub 2011 Aug 25.

Liver Cancer Institute, Zhong Shan Hospital and Shanghai Medical School, Key Laboratory for Carcinogenesis & Cancer Invasion, Shanghai, PR China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-11-0950DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3233659PMC
March 2012