Rob Willemsen

Rob Willemsen

UNVERIFIED PROFILE

Are you Rob Willemsen?   Register this Author

Register author
Rob Willemsen

Rob Willemsen

Publications by authors named "Rob Willemsen"

Are you Rob Willemsen?   Register this Author

100Publications

2420Reads

47Profile Views

BC RNA Mislocalization in the Fragile X Premutation.

eNeuro 2018 Mar-Apr;5(2). Epub 2018 Apr 19.

The Robert F. Furchgott Center for Neural and Behavioral Science, State University of New York Downstate Medical Center, Brooklyn, New York 11203.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1523/ENEURO.0091-18.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952321PMC
January 2019

Potential pathogenic mechanisms underlying Fragile X Tremor Ataxia Syndrome: RAN translation and/or RNA gain-of-function?

Eur J Med Genet 2018 Nov 6;61(11):674-679. Epub 2017 Dec 6.

Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), INSERM U964, CNRS UMR7104, University of Strasbourg, 67400 Illkirch, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejmg.2017.11.001DOI Listing
November 2018

Paradoxical effect of baclofen on social behavior in the fragile X syndrome mouse model.

Brain Behav 2018 06 26;8(6):e00991. Epub 2018 Apr 26.

Department of Clinical Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/brb3.991DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991574PMC
June 2018

Combination Therapy in Fragile X Syndrome; Possibilities and Pitfalls Illustrated by Targeting the mGluR5 and GABA Pathway Simultaneously.

Front Mol Neurosci 2017 7;10:368. Epub 2017 Nov 7.

Department of Clinical Genetics, Erasmus University Medical Center, Rotterdam, Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fnmol.2017.00368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681991PMC
November 2017

Selective rescue of heightened anxiety but not gait ataxia in a premutation 90CGG mouse model of Fragile X-associated tremor/ataxia syndrome.

Hum Mol Genet 2017 06;26(11):2133-2145

Department of Genetics and Molecular Neurobiology, Institute of Biology, Otto-von-Guericke University, 39120 Magdeburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/ddx108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075076PMC
June 2017

Impaired GABAergic inhibition in the hippocampus of Fmr1 knockout mice.

Neuropharmacology 2017 04 21;116:71-81. Epub 2016 Dec 21.

Laboratory of Biological Psychology, KU Leuven, Leuven, Belgium. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuropharm.2016.12.010DOI Listing
April 2017

Translation of Expanded CGG Repeats into FMRpolyG Is Pathogenic and May Contribute to Fragile X Tremor Ataxia Syndrome.

Neuron 2017 Jan 5;93(2):331-347. Epub 2017 Jan 5.

Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), INSERM U964, CNRS UMR7104, University of Strasbourg, 67400 Illkirch, France; Université de Strasbourg, 67000 Strasbourg, France; Centre National de la Recherche Scientifique, UMR7104, 67400 Illkirch, France; Institut National de la Santé et de la Recherche Médicale, U964, 67400 Illkirch, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuron.2016.12.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5263258PMC
January 2017

New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics.

Hum Mol Genet 2017 01;26(2):438-453

Statistical Genetics, QIMR Berghofer Medical Research Institute, Royal Brisbane Hospital, Brisbane, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/ddw399DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968632PMC
January 2017

The quest for targeted therapy in fragile X syndrome.

Expert Opin Ther Targets 2015 14;19(10):1277-81. Epub 2015 Aug 14.

a Erasmus MC, Department of Clinical Genetics , P.O. Box 2040, 3000 CA Rotterdam, The Netherlands +31 107 043 152 ;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1517/14728222.2015.1079176DOI Listing
May 2016

Synaptic vesicle dynamic changes in a model of fragile X.

Mol Autism 2016 1;7:17. Epub 2016 Mar 1.

Cambridge Centre for Neuropsychiatric Research, Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13229-016-0080-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772588PMC
April 2016

Heritabilities, proportions of heritabilities explained by GWAS findings, and implications of cross-phenotype effects on PR interval.

Hum Genet 2015 Nov 18;134(11-12):1211-9. Epub 2015 Sep 18.

Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00439-015-1595-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628620PMC
November 2015

In vivo synaptic transmission and morphology in mouse models of Tuberous sclerosis, Fragile X syndrome, Neurofibromatosis type 1, and Costello syndrome.

Front Cell Neurosci 2015 3;9:234. Epub 2015 Jul 3.

Department of Neuroscience, Erasmus MC, University Medical Center Rotterdam Rotterdam, Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fncel.2015.00234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490249PMC
July 2015

Reply: PRKAR1B mutations are a rare cause of FUS negative neuronal intermediate filament inclusion disease.

Brain 2015 Jun 19;138(Pt 6):e358. Epub 2014 Nov 19.

1 Department of Neurology, Erasmus Medical Centre, 3015 CE Rotterdam, The Netherlands 7 Alzheimer Centre, Neuroscience Campus Amsterdam, 1007 MB Amsterdam, The Netherlands 8 Department of Neurology, Neuroscience Campus Amsterdam, 1007 MB Amsterdam, The Netherlands

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/brain/awu333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614125PMC
June 2015

A novel fragile X syndrome mutation reveals a conserved role for the carboxy-terminus in FMRP localization and function.

EMBO Mol Med 2015 Apr;7(4):423-37

VIB Center for the Biology of Disease, VIB, Leuven, Belgium Center for Human Genetics, University of Leuven School of Medicine and University Hospitals Leuven, Leuven, Belgium Program in Molecular and Developmental Genetics, Doctoral School of Biomedical Sciences, University of Leuven, Leuven, Belgium

View Article

Download full-text PDF

Source
http://dx.doi.org/10.15252/emmm.201404576DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403044PMC
April 2015

DAZL limits pluripotency, differentiation, and apoptosis in developing primordial germ cells.

Stem Cell Reports 2014 Nov 11;3(5):892-904. Epub 2014 Oct 11.

Hubrecht Institute and University Medical Center, Uppsalalaan 8, 3584 CT Utrecht, the Netherlands; Department of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 104, 3584 CM Utrecht, the Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.stemcr.2014.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235140PMC
November 2014

Translational endpoints in fragile X syndrome.

Neurosci Biobehav Rev 2014 Oct 30;46 Pt 2:256-69. Epub 2013 Oct 30.

Department of Clinical Genetics, Erasmus Medical Centre, Rotterdam, the Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neubiorev.2013.10.012DOI Listing
October 2014

Use of model systems to understand the etiology of fragile X-associated primary ovarian insufficiency (FXPOI).

J Neurodev Disord 2014 13;6(1):26. Epub 2014 Aug 13.

Laboratory of Molecular and Cellular Biology, NIDDK, National Institutes of Health, Bethesda, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1866-1955-6-26DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139715PMC
August 2014

Blood expression profiles of fragile X premutation carriers identify candidate genes involved in neurodegenerative and infertility phenotypes.

Neurobiol Dis 2014 May 10;65:43-54. Epub 2014 Jan 10.

Genomics and Disease Group, Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), Barcelona 08003, Catalonia, Spain; Universitat Pompeu Fabra (UPF), Barcelona 08003, Catalonia, Spain; Hospital del Mar Medical Research Institute (IMIM), Barcelona 08003, Catalonia, Spain; CIBER de Epidemiología y Salud Pública (CIBERESP), CRG, Barcelona 08003, Catalonia, Spain. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nbd.2013.12.020DOI Listing
May 2014

Rescue of dendritic spine phenotype in Fmr1 KO mice with the mGluR5 antagonist AFQ056/Mavoglurant.

Psychopharmacology (Berl) 2014 Mar 21;231(6):1227-35. Epub 2012 Dec 21.

CBG-Department of Clinical Genetics, Erasmus Medical Centre, Dr. Molewaterplein 55, 3015GE, Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00213-012-2947-yDOI Listing
March 2014

Reduced activity-dependent protein levels in a mouse model of the fragile X premutation.

Neurobiol Learn Mem 2014 Mar 23;109:160-8. Epub 2014 Jan 23.

Department of Neurological Surgery, School of Medicine, University of California, Davis, Davis, CA, USA; NeuroTherapeutic Research Institute, University of California, Davis, Davis, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nlm.2014.01.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966028PMC
March 2014

The 3' UTR of FMR1 mRNA is a target of miR-101, miR-129-5p and miR-221: implications for the molecular pathology of FXTAS at the synapse.

Hum Mol Genet 2013 May 5;22(10):1971-82. Epub 2013 Feb 5.

CNRS UMR 7275, Institute of Molecular and Cellular Pharmacology, Valbonne Sophia-Antipolis, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/ddt044DOI Listing
May 2013

Chronic administration of AFQ056/Mavoglurant restores social behaviour in Fmr1 knockout mice.

Behav Brain Res 2013 Feb 6;239:72-9. Epub 2012 Nov 6.

Laboratory of Biological Psychology, Faculty of Psychology and Educational Sciences, KU Leuven, Tiensestraat 102, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbr.2012.10.059DOI Listing
February 2013

The zebrafish homologue of Parkinson's disease ATP13A2 is essential for embryonic survival.

Brain Res Bull 2013 Jan 31;90:118-26. Epub 2012 Oct 31.

Cell and Molecular Neuroscience Unit, Instituto de Medicina Molecular, Lisboa, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.brainresbull.2012.09.017DOI Listing
January 2013

CGG trinucleotide repeat length modulates neural plasticity and spatiotemporal processing in a mouse model of the fragile X premutation.

Hippocampus 2012 Dec 18;22(12):2260-75. Epub 2012 Jun 18.

Department of Neurological Surgery, School of Medicine, University of California- Davis, Davis, CA 95616, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hipo.22043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449027PMC
December 2012

Perturbation of dendritic protrusions in intellectual disability.

Prog Brain Res 2012 ;197:153-68

Department of Physiology and Neuroscience, New York University, School of Medicine, New York, NY, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/B978-0-444-54299-1.00008-XDOI Listing
September 2012

Distribution and frequency of intranuclear inclusions in female CGG KI mice modeling the fragile X premutation.

Brain Res 2012 Sep 11;1472:124-37. Epub 2012 Jul 11.

Department of Neurological Surgery, School of Medicine, University of California Davis, Davis, CA 95616, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.brainres.2012.06.052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572858PMC
September 2012

Locomotor activity assay in zebrafish larvae: influence of age, strain and ethanol.

Neurotoxicol Teratol 2012 Jul 29;34(4):425-33. Epub 2012 Mar 29.

TNO, Research group Quality and Safety, Zeist, The Netherlands.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S08920362120004
Publisher Site
http://dx.doi.org/10.1016/j.ntt.2012.03.002DOI Listing
July 2012

Spatiotemporal processing deficits in female CGG KI mice modeling the fragile X premutation.

Behav Brain Res 2012 Jul 26;233(1):29-34. Epub 2012 Apr 26.

Department of Neurological Surgery, School of Medicine, University of California, Davis, Davis, CA 95616, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbr.2012.04.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378809PMC
July 2012

Mouse models of the fragile x premutation and the fragile X associated tremor/ataxia syndrome.

Results Probl Cell Differ 2012 ;54:255-69

Department of Neurological Surgery, University of California, Davis, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-3-642-21649-7_14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313770PMC
February 2012

Female CGG knock-in mice modeling the fragile X premutation are impaired on a skilled forelimb reaching task.

Neurobiol Learn Mem 2012 Feb 21;97(2):229-34. Epub 2011 Dec 21.

Department of Neurological Surgery, School of Medicine, University of California, Davis, Davis, CA 95616, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nlm.2011.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278548PMC
February 2012

Motor deficits on a ladder rung task in male and female adolescent and adult CGG knock-in mice.

Behav Brain Res 2011 Sep 31;222(1):117-21. Epub 2011 Mar 31.

Department of Neurological Surgery, School of Medicine, University of California, Davis; Davis, CA 95616, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbr.2011.03.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3095688PMC
September 2011

Differential usage of transcriptional start sites and polyadenylation sites in FMR1 premutation alleles.

Nucleic Acids Res 2011 Aug 7;39(14):6172-85. Epub 2011 Apr 7.

Department of Biochemistry and Molecular Medicine, University of California, Davis School of Medicine, Davis, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gkr100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152321PMC
August 2011

AFQ056, a new mGluR5 antagonist for treatment of fragile X syndrome.

Neurobiol Dis 2011 Jun 21;42(3):311-7. Epub 2011 Feb 21.

Department of Clinical Genetics, Erasmus MC, Dr Molewaterplein 50, 3015 GE Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nbd.2011.01.022DOI Listing
June 2011

Rare intranuclear inclusions in the brains of 3 older adult males with fragile x syndrome: implications for the spectrum of fragile x-associated disorders.

J Neuropathol Exp Neurol 2011 Jun;70(6):462-9

NeuroTherapeutics Research Institute and Department of Neurological Surgery, University of California, Davis School of Medicine, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/NEN.0b013e31821d3194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109086PMC
June 2011

Subregion-specific dendritic spine abnormalities in the hippocampus of Fmr1 KO mice.

Neurobiol Learn Mem 2011 May 1;95(4):467-72. Epub 2011 Mar 1.

CBG-Department of Clinical Genetics, Erasmus MC, Dr. Molewaterplein 50, 3015 GE Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nlm.2011.02.009DOI Listing
May 2011

Premutation CGG-repeat expansion of the Fmr1 gene impairs mouse neocortical development.

Hum Mol Genet 2011 Jan 8;20(1):64-79. Epub 2010 Oct 8.

Department of Pathology, Institute for Pediatric Regenerative Medicine--Shriners Hospital, School of Medicine, UC Davis, Sacramento, CA 95817, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/ddq432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000676PMC
January 2011

Temporal ordering deficits in female CGG KI mice heterozygous for the fragile X premutation.

Behav Brain Res 2010 Dec 15;213(2):263-8. Epub 2010 May 15.

Program in Neuroscience, University of California-Davis, 1515 Newton Court, Davis, CA 95616, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbr.2010.05.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902565PMC
December 2010

Glut1/SLC2A1 is crucial for the development of the blood-brain barrier in vivo.

Ann Neurol 2010 Dec;68(6):835-44

Department of Pathology, Erasmus Medical Center, Rotterdam, the Netherlands.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/ana.22318
Publisher Site
http://dx.doi.org/10.1002/ana.22318DOI Listing
December 2010

Potential therapeutic interventions for fragile X syndrome.

Trends Mol Med 2010 Nov 21;16(11):516-27. Epub 2010 Sep 21.

CBG-Department of Clinical Genetics, Erasmus MC, Dr. Molewaterplein 50, 3015 GE, Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molmed.2010.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981507PMC
November 2010

FMR1 protein expression in blood smears for fragile X syndrome diagnosis in a Mexican population sample.

Genet Test Mol Biomarkers 2010 Aug;14(4):511-4

División de Genética, Centro de Investigación Biomédica de Occidente, Instituto Mexicano del Seguro Social, Guadalajara, Jalisco, México.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/gtmb.2009.0172DOI Listing
August 2010

Dauer pheromone and G-protein signaling modulate the coordination of intraflagellar transport kinesin motor proteins in C. elegans.

J Cell Sci 2010 Jun 25;123(Pt 12):2077-84. Epub 2010 May 25.

Department of Cell Biology and Genetics, Erasmus MC, Rotterdam, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/jcs.062885DOI Listing
June 2010

Images. Different patterns of circulatory shunting in zebrafish caldesmon morphants: a digital motion analysis.

Heart Lung Circ 2010 Apr 14;19(4):251-2. Epub 2009 Nov 14.

Department of Pathology, Erasmus Medical Center, Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hlc.2009.08.007DOI Listing
April 2010

Ubiquitin-positive intranuclear inclusions in neuronal and glial cells in a mouse model of the fragile X premutation.

Brain Res 2010 Mar 4;1318:155-66. Epub 2010 Jan 4.

Department of Neurological Surgery, University of California, Davis; Davis, CA 95618, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.brainres.2009.12.077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086812PMC
March 2010

Mouse models of fragile X-associated tremor ataxia.

J Investig Med 2009 Dec;57(8):837-41

Department of Neurological Surgery and the Neurotherapeutics Research Institute, University of California Davis, Davis, CA 95616, USA.

View Article

Download full-text PDF

Source
http://jim.bmj.com/lookup/doi/10.2310/JIM.0b013e3181af59d6
Publisher Site
http://dx.doi.org/10.2310/JIM.0b013e3181af59d6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787904PMC
December 2009

Progressive spatial processing deficits in a mouse model of the fragile X premutation.

Behav Neurosci 2009 Dec;123(6):1315-24

Program in Neuroscience, University of California, Davis, Davis, CA 95616, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1037/a0017616DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410547PMC
December 2009

Oxazolone-induced enterocolitis in zebrafish depends on the composition of the intestinal microbiota.

Gastroenterology 2009 Nov 19;137(5):1757-67.e1. Epub 2009 Aug 19.

Laboratory of Pediatrics, Pediatric Gastroenterology, Erasmus Medical Center, Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.gastro.2009.07.069DOI Listing
November 2009

Generation and characterization of FMR1 knockout zebrafish.

PLoS One 2009 Nov 19;4(11):e7910. Epub 2009 Nov 19.

Hubrecht Institute, Royal Academy of Arts and Sciences and University Medical Center Utrecht, Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0007910PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774943PMC
November 2009

Images in cardiovascular medicine. Functional cardiac phenotypes in zebrafish caldesmon morphants: a digital motion analysis.

Circulation 2009 Oct;120(17):e145-6

Department of Pathology, Erasmus Medical Center, Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCULATIONAHA.109.881029DOI Listing
October 2009

Ultrastructural analysis of the functional domains in FMRP using primary hippocampal mouse neurons.

Neurobiol Dis 2009 Aug 21;35(2):241-50. Epub 2009 May 21.

CBG Department of Clinical Genetics, Erasmus MC, Dr. Molewaterplein 50, 3015 GE, P.O. Box 2040, Rotterdam 3000 CA, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nbd.2009.05.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757577PMC
August 2009

Reduction in fragile X related 1 protein causes cardiomyopathy and muscular dystrophy in zebrafish.

J Exp Biol 2009 Aug;212(Pt 16):2564-70

CBG-Department of Clinical Genetics, Erasmus MC, 3015 CE Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/jeb.032532DOI Listing
August 2009

Ectopic expression of CGG containing mRNA is neurotoxic in mammals.

Hum Mol Genet 2009 Jul 18;18(13):2443-51. Epub 2009 Apr 18.

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/ddp182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694692PMC
July 2009

FMR1: a gene with three faces.

Biochim Biophys Acta 2009 Jun 21;1790(6):467-77. Epub 2009 Feb 21.

Department of Clinical Genetics, Erasmus MC, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbagen.2009.02.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2692361PMC
June 2009

Haemoglobin staining for in vivo portraying of functional vasculature in experimental zebrafish embryos.

Biochem Biophys Res Commun 2009 Mar 5;380(4):823-4. Epub 2009 Feb 5.

Department of Pathology, Erasmus Medical Center, Office JNI Room 230-c, Dr. Molewaterplein 50, PO box 2040, 3000 CA, Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbrc.2009.01.175DOI Listing
March 2009

Microsatellite repeat instability and neurological disease.

Bioessays 2009 Jan;31(1):71-83

Department of Clinical Genetics, ErasmusMC, Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/bies.080122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321794PMC
January 2009