Publications by authors named "Rob Pieters"

100Publications

Flowcytometric evaluation of cerebrospinal fluid in childhood ALL identifies CNS involvement better then conventional cytomorphology.

Leukemia 2020 Aug 27. Epub 2020 Aug 27.

Department of Immunology, Laboratory Medical Immunology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/s41375-020-01029-9DOI Listing
August 2020

Increasing incidence of cancer and stage migration towards advanced disease in children and young adolescents in the Netherlands, 1990-2017.

Eur J Cancer 2020 07 7;134:115-126. Epub 2020 Jun 7.

Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands; Department of Research and Development, Netherlands Comprehensive Cancer Organisation (IKNL), Utrecht, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2020.04.011DOI Listing
July 2020

Individualized dosing guidelines for PEGasparaginase and factors influencing the clearance: a population pharmacokinetic model.

Haematologica 2020 Apr 23. Epub 2020 Apr 23.

Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands

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http://dx.doi.org/10.3324/haematol.2019.242289DOI Listing
April 2020

Individualized Asparaginase Dosing in Childhood Acute Lymphoblastic Leukemia.

J Clin Oncol 2020 03 10;38(7):715-724. Epub 2020 Jan 10.

Pediatric Oncology and Hematology, Erasmus MC-Sophia Children's Hospital, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1200/JCO.19.02292DOI Listing
March 2020

Acute lymphoblastic leukaemia patients treated with PEGasparaginase develop antibodies to PEG and the succinate linker.

Br J Haematol 2020 May 27;189(3):442-451. Epub 2019 Dec 27.

Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, the Netherlands.

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http://dx.doi.org/10.1111/bjh.16254DOI Listing
May 2020

Treatment-related mortality in children with cancer: Prevalence and risk factors.

Eur J Cancer 2019 11 27;121:113-122. Epub 2019 Sep 27.

University of Groningen, University Medical Center Groningen, Beatrix Children's Hospital, Department of Pediatric Oncology/Hematology, Groningen, the Netherlands; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.

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http://dx.doi.org/10.1016/j.ejca.2019.08.008DOI Listing
November 2019

A European paediatric cancer mission: aspiration or reality?

Lancet Oncol 2019 09;20(9):1200-1202

Department of Pediatrics and Adolescent Medicine, Rigshospitalet University Hospital, and Institute of Clinical Medicine, Faculty of Medicine, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1016/S1470-2045(19)30487-5DOI Listing
September 2019

The effect of asparaginase therapy on methotrexate toxicity and efficacy in children with acute lymphoblastic leukemia.

Leuk Lymphoma 2019 12 23;60(12):3002-3010. Epub 2019 May 23.

Department of Pediatric Oncology and Hematology, Erasmus MC - Sophia Children's Hospital, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1080/10428194.2019.1613537DOI Listing
December 2019

Fibroblast growth factor receptor signaling in pediatric B-cell precursor acute lymphoblastic leukemia.

Sci Rep 2019 02 12;9(1):1875. Epub 2019 Feb 12.

Department of Pediatric Oncology, Erasmus Medical Center - Sophia Children's Hospital, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/s41598-018-38169-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372586PMC
February 2019

How I treat infant leukemia.

Blood 2019 01 20;133(3):205-214. Epub 2018 Nov 20.

Department of Pediatrics and.

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http://dx.doi.org/10.1182/blood-2018-04-785980DOI Listing
January 2019

A cost-effectiveness analysis of Erwinia asparaginase therapy in children with acute lymphoblastic leukemia.

Pediatr Blood Cancer 2019 01 23;66(1):e27458. Epub 2018 Sep 23.

Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.

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http://dx.doi.org/10.1002/pbc.27458DOI Listing
January 2019

Health-related fitness in very long-term survivors of childhood cancer: A cross-sectional study.

Pediatr Blood Cancer 2018 04 22;65(4). Epub 2017 Dec 22.

Department of Pediatric Oncology and Hematology, Erasmus MC Sophia Children's Hospital, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1002/pbc.26907DOI Listing
April 2018

High expression does not serve as an effective therapeutic target in -deleted B-cell precursor acute lymphoblastic leukemia.

Haematologica 2018 02 23;103(2):e73-e77. Epub 2017 Nov 23.

Department of Pediatric Oncology, Erasmus Medical Center-Sophia Children's Hospital, Rotterdam, the Netherlands

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http://dx.doi.org/10.3324/haematol.2017.171702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792290PMC
February 2018

A cost analysis of individualized asparaginase treatment in pediatric acute lymphoblastic leukemia.

Pediatr Blood Cancer 2017 Dec 2;64(12). Epub 2017 Aug 2.

Pediatric Oncology and Hematology, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1002/pbc.26651DOI Listing
December 2017

The miR-1206 microRNA variant is associated with methotrexate-induced oral mucositis in pediatric acute lymphoblastic leukemia.

Pharmacogenet Genomics 2017 08;27(8):303-306

aDepartment of Genetics, Physical Anthropology and Animal Physiology, Faculty of Medicine and Nursery bBioCruces Health Research Institute, University of the Basque Country (UPV/EHU), Leioa, Spain cPrincess Máxima Center for Pediatric Oncology, Utrecht dDepartment of Clinical Chemistry, Erasmus Medical Center eDepartment of Pediatric Oncology/Hematology, Erasmus Medical Center-Sophia's Children's Hospital, Rotterdam fDepartment of Clinical Chemistry, VU Medical Center, Amsterdam gDepartment of Pediatric Oncology, Beatrix Children's Hospital, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands hDepartment of Oncology, St Jude Children's Research Hospital, Memphis, Tennessee, USA.

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http://dx.doi.org/10.1097/FPC.0000000000000291DOI Listing
August 2017

Acute lymphoblastic leukemia cells create a leukemic niche without affecting the CXCR4/CXCL12 axis.

Haematologica 2017 10 15;102(10):e389-e393. Epub 2017 Jun 15.

Department of Pediatric Oncology, Erasmus MC, Sophia Children's Hospital, Rotterdam, the Netherlands

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http://dx.doi.org/10.3324/haematol.2016.159517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622868PMC
October 2017

Loss of CD44 Expression from Early Progenitor Cells Marks T-Cell Lineage Commitment in the Human Thymus.

Front Immunol 2017 20;8:32. Epub 2017 Jan 20.

Princess Máxima Center for Pediatric Oncology, Utrecht, Netherlands; Department of Pediatric Oncology/Hematology, Erasmus Medical Center-Sophia Children's Hospital, Rotterdam, Netherlands.

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http://journal.frontiersin.org/article/10.3389/fimmu.2017.00
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http://dx.doi.org/10.3389/fimmu.2017.00032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247458PMC
January 2017

PHF6 mutations in paediatric acute myeloid leukaemia.

Br J Haematol 2016 12 21;175(5):967-971. Epub 2015 Dec 21.

Paediatric Oncology/Haematology, Erasmus MC-Sophia Children's Hospital, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1111/bjh.13891DOI Listing
December 2016

Genetic variation and bone mineral density in long-term adult survivors of childhood cancer.

Pediatr Blood Cancer 2016 12 31;63(12):2212-2220. Epub 2016 Aug 31.

Department of Pediatric Oncology/Hematology, Erasmus MC-Sophia Children's Hospital Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1002/pbc.26198DOI Listing
December 2016

Gonadal function in boys with newly diagnosed cancer before the start of treatment.

Hum Reprod 2016 11 28;31(11):2613-2618. Epub 2016 Sep 28.

Department of Pediatric Oncology/Hematology, Erasmus MC-Sophia Children's Hospital, Dr. Molewaterplein 60, 3015 GJ Rotterdam, The Netherlands

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http://dx.doi.org/10.1093/humrep/dew234DOI Listing
November 2016

The relevance of PTEN-AKT in relation to NOTCH1-directed treatment strategies in T-cell acute lymphoblastic leukemia.

Haematologica 2016 09;101(9):1010-7

Department of Pediatric Oncology/Hematology, Erasmus MC Rotterdam-Sophia Children's Hospital, Rotterdam, The Netherlands Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands

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http://dx.doi.org/10.3324/haematol.2016.146381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5060017PMC
September 2016

Predicting the neurobehavioral side effects of dexamethasone in pediatric acute lymphoblastic leukemia.

Psychoneuroendocrinology 2016 10 11;72:190-5. Epub 2016 Jul 11.

Department of Pediatric Oncology, Erasmus MC - Sophia Children's Hospital, P.O. Box 2060, 3000 CB, Rotterdam, The Netherlands; Princess Máxima Center for Pediatric Oncology, P.O. Box 85090, 3508 AB, Utrecht, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.psyneuen.2016.07.006DOI Listing
October 2016

Allergic-like reactions to asparaginase: Atypical allergies without asparaginase inactivation.

Pediatr Blood Cancer 2016 11 4;63(11):1928-34. Epub 2016 Jul 4.

Pediatric Oncology and Hematology, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1002/pbc.26123DOI Listing
November 2016

Genetic Biomarkers to Identify the Risk of Osteonecrosis in Children with Acute Lymphoblastic Leukemia.

Mol Diagn Ther 2016 12;20(6):519-522

Department of Pediatric Oncology/Hematology, Erasmus MC-Sophia Children's Hospital Rotterdam, Dr. Molewaterplein 60, 3015 GJ, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s40291-016-0226-zDOI Listing
December 2016

Lentiviral gene transfer into human and murine hematopoietic stem cells: size matters.

BMC Res Notes 2016 Jun 16;9:312. Epub 2016 Jun 16.

Department of Pediatric Oncology/Hematology, Erasmus MC Rotterdam-Sophia Children's Hospital, Wytemaweg 80, 3015 CN, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1186/s13104-016-2118-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910193PMC
June 2016

Successful Therapy Reduction and Intensification for Childhood Acute Lymphoblastic Leukemia Based on Minimal Residual Disease Monitoring: Study ALL10 From the Dutch Childhood Oncology Group.

J Clin Oncol 2016 08 6;34(22):2591-601. Epub 2016 Jun 6.

Rob Pieters, Peter Hoogerbrugge, and Gertjan Kaspers, Princess Máxima Center for Pediatric Oncology, Utrecht; Rob Pieters, Hester de Groot-Kruseman, Marta Fiocco, and Valerie De Haas, Dutch Childhood Oncology Group, The Hague; Vincent Van der Velden and Jacques Van Dongen, University Medical Center Rotterdam, Rotterdam; Marta Fiocco, Leiden University, Leiden; Henk van den Berg, Academic Medical Center; Gertjan Kaspers, Free University Hospital Amsterdam; Ellen Van der Schoot, Sanquin Research, Amsterdam; Evelien de Bont, University of Groningen, Groningen, the Netherlands; and R. Maarten Egeler, The Hospital for Sick Children, Toronto, Canada.

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http://dx.doi.org/10.1200/JCO.2015.64.6364DOI Listing
August 2016

HOXA-activated early T-cell progenitor acute lymphoblastic leukemia: predictor of poor outcome?

Haematologica 2016 06;101(6):654-6

The Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.

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http://dx.doi.org/10.3324/haematol.2016.145391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013942PMC
June 2016

Hydrocortisone as an Intervention for Dexamethasone-Induced Adverse Effects in Pediatric Patients With Acute Lymphoblastic Leukemia: Results of a Double-Blind, Randomized Controlled Trial.

J Clin Oncol 2016 07 9;34(19):2287-93. Epub 2016 May 9.

Lidewij T. Warris, Marry M. van den Heuvel-Eibrink, Femke K. Aarsen, Saskia M.F. Pluijm, Christian M. Zwaan, Rob Pieters, and Erica L.T. van den Akker, Erasmus MC-Sophia Children's Hospital, Rotterdam; Cor van den Bos, Academic Medical Center-Emma Children's Hospital; Margreet A. Veening, Vrije Universiteit Medical Center; Helene H. Thygesen, Netherlands Cancer Institute, Amsterdam; Marc B. Bierings, University Medical Center Utrecht-Wilhelmina Children's Hospital; Lidewij T. Warris, Marry M. van den Heuvel-Eibrink, Marc B. Bierings, and Rob Pieters, Princess Máxima Center for Pediatric Oncology, Utrecht; Wim J.E. Tissing, University Medical Center Groningen, Groningen, the Netherlands.

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http://dx.doi.org/10.1200/JCO.2015.66.0761DOI Listing
July 2016

The association of aberrant folylpolyglutamate synthetase splicing with ex vivo methotrexate resistance and clinical outcome in childhood acute lymphoblastic leukemia.

Haematologica 2016 07 1;101(7):e291-4. Epub 2016 Apr 1.

Dept of Pediatric Oncology/Hematology, VU University Medical Center, Amsterdam, The Netherlands Dept. of Hematology, VU University Medical Center, Amsterdam, The Netherlands

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http://dx.doi.org/10.3324/haematol.2016.142794DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004475PMC
July 2016

Participation in a clinical trial for a child with cancer is burdensome for a minority of children.

Acta Paediatr 2016 Sep 27;105(9):1100-4. Epub 2016 Apr 27.

University of Southampton, Faculty of Health Sciences, Southampton, United Kingdom.

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http://dx.doi.org/10.1111/apa.13405DOI Listing
September 2016

Versican expression is an adverse prognostic factor in MLL-rearranged infant acute lymphoblastic leukaemia.

Eur J Cancer 2016 Apr 19;57:87-90. Epub 2016 Feb 19.

Pediatric Oncology/Hematology, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2015.12.031DOI Listing
April 2016

Influence of Cranial Radiotherapy on Outcome in Children With Acute Lymphoblastic Leukemia Treated With Contemporary Therapy.

J Clin Oncol 2016 Mar 11;34(9):919-26. Epub 2016 Jan 11.

Ajay Vora, Sheffield Children's Hospital and University of Sheffield, Sheffield; Nicholas Goulden, Great Ormond Street Hospital, London, United Kingdom; Anita Andreano and Maria Grazia Valsecchi, School of Medicine and Surgery, University of Milano-Bicocca, Milan; Andrea Biondi, University of Milano-Bicocca, Monza; Franco Locatelli, Bambino Gesù Children's Hospital, Rome, and University of Pavia, Pavia, Italy; Ching-Hon Pui, St Jude Children's Research Hospital and University of Tennessee Health Science Center, Memphis, TN; Stephen P. Hunger, Children's Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine, Philadelphia, PA; Lewis B. Silverman, Dana-Faber Cancer Institute and Boston Children's Hospital, Boston, MA; Meenakshi Devidas, Children's Oncology Group Statistics and Data Center and University of Florida, Gainesville, FL; Martin Schrappe and Anja Moericke, University Medical Centre and Christian-Albrechts-University, Kiel; Gabriele Escherich, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany; Mervi Taskinen, Helsinki University Hospital, Helsinki, Finland; Rob Pieters, Princess Máxima Center for Pediatric Oncology, Utrecht, and Dutch Childhood Oncology Group, the Hague, the Netherlands; and Keizo Horibe, National Hospital Organization Nagoya Medical Center, Nagoya, Japan.

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http://dx.doi.org/10.1200/JCO.2015.64.2850DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871998PMC
March 2016

Recurrent translocation t(10;17)(p15;q21) in minimally differentiated acute myeloid leukemia results in ZMYND11/MBTD1 fusion.

Genes Chromosomes Cancer 2016 Mar 26;55(3):237-41. Epub 2015 Nov 26.

Erasmus MC-Sophia Children's Hospital, Pediatric Oncology/Hematology, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1002/gcc.22326DOI Listing
March 2016

Talking about Death with Children with Incurable Cancer: Perspectives from Parents.

J Pediatr 2015 Dec 1;167(6):1320-6. Epub 2015 Oct 1.

University of Southampton, Faculty of Health Sciences, Southampton, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jpeds.2015.08.066DOI Listing
December 2015

Ammonia Levels Should Not Be Used as a Surrogate Marker of Levels of Asparaginase Activity in Acute Lymphoblastic Leukemia Patients.

Pediatr Blood Cancer 2016 Mar 23;63(3):564-5. Epub 2015 Sep 23.

Department of Pediatric Oncology/Hematology, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1002/pbc.25767DOI Listing
March 2016

Childhood Acute Lymphoblastic Leukemia: Progress Through Collaboration.

J Clin Oncol 2015 Sep 24;33(27):2938-48. Epub 2015 Aug 24.

Ching-Hon Pui, Jun J. Yang, James R. Downing, Williams E. Evans, Mary V. Relling, and Charles G. Mullighan, St Jude Children's Research Hospital and the University of Tennessee Health Science Center, Memphis, TN; Stephen P. Hunger, University of Colorado School of Medicine and the University of Colorado Cancer Center and Children's Hospital Colorado, Aurora, CO; Rob Pieters, Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands; Martin Schrappe, University Medical Center Schleswig-Holstein, Christian-Albrechts-University, Kiel; Gabriele Escherich, Clinic of Pediatric Hematology and Oncology, University Medical Center Hamburg Eppendorf, Hamburg, Germany; Andrea Biondi, Clinica Pediatrica and Centro Ricerca Tettamanti, Università di Milano-Bicocca, Monza, Italy; Ajay Vora, Children's Cancer Group, School of Cancer, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, United Kingdom; André Baruchel, Hôpital Robert Debré and University of Paris Diderot, Paris, France; Lewis B. Silverman, Dana-Farber Cancer Institute and Boston Children's Hospital, Boston, MA; Kjeld Schmiegelow, Institute of Clinical Medicine, University of Copenhagen and Juliane Marie Centre, the University Hospital Rigshospitalet, Copenhagen, Denmark; Keizo Horibe, Nagoya Medical Center, Clinical Research Center, Nagoya, Japan; Yves C.M. Benoit, Universiteit Gent, Gent, Belgium; Shai Izraeli, Chaim Sheba Medical Center and Sackler Medical School, Tel Aviv University, Tel Aviv, Israel; Allen Eng Juh Yeoh, Yong Loo Lin School of Medicine and Cancer Science Institute, National University of Singapore, and Viva-University Children's Cancer Centre, National University Hospital, Singapore; and Der-Cherng Liang, Mackay Memorial Hospital, Taipei, Taiwan.

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http://jco.ascopubs.org/content/early/2015/08/21/JCO.2014.59
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http://200.40.135.66:90/toc/0873/2015/0873-20150920-27-01.pd
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http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2014.59.1636
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http://dx.doi.org/10.1200/JCO.2014.59.1636DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567699PMC
September 2015

End-of-Life Decisions in Pediatric Cancer Patients.

J Palliat Med 2015 Aug;18(8):697-702

4 Princess Maxima Center for Pediatric Oncology , Utrecht, The Netherlands .

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http://www.liebertpub.com/doi/10.1089/jpm.2015.29000.rbvl
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http://dx.doi.org/10.1089/jpm.2015.29000.rbvlDOI Listing
August 2015

The potential of clofarabine in MLL-rearranged infant acute lymphoblastic leukaemia.

Eur J Cancer 2015 Sep 15;51(14):2008-21. Epub 2015 Jul 15.

Department of Pediatric Oncology/Hematology, Erasmus MC - Sophia Children's Hospital Rotterdam, Wytemaweg 80, P.O. Box 2060, 3000 CB Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2015.06.117DOI Listing
September 2015

BCR-ABL1-like cases in pediatric acute lymphoblastic leukemia: a comparison between DCOG/Erasmus MC and COG/St. Jude signatures.

Haematologica 2015 Sep 4;100(9):e354-7. Epub 2015 Jun 4.

Department of Pediatric Oncology/Hematology, Erasmus MC -Sophia Children's Hospital, Rotterdam, The Netherlands Dutch Childhood Oncology Group, The Hague, The Netherlands

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http://dx.doi.org/10.3324/haematol.2015.124941DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800707PMC
September 2015

Methotrexate resistance in relation to treatment outcome in childhood acute lymphoblastic leukemia.

J Hematol Oncol 2015 May 29;8:61. Epub 2015 May 29.

Department of Pediatric Oncology/Hematology, VUmc Cancer Center Amsterdam, VU University Medical Center, Room CCA 4.28, De Boelelaan 1117, 1081HV, Amsterdam, The Netherlands.

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http://www.jhoonline.org/content/8/1/61
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http://dx.doi.org/10.1186/s13045-015-0158-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455979PMC
May 2015

Parents' Faith and Hope during the Pediatric Palliative Phase and the Association with Long-Term Parental Adjustment.

J Palliat Med 2015 May 13;18(5):402-7. Epub 2015 Feb 13.

1 Department of Paediatric Oncology/Haematology, Erasmus MC-Sophia Children's Hospital , Rotterdam, The Netherlands .

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http://dx.doi.org/10.1089/jpm.2014.0287DOI Listing
May 2015

Towards personalized therapy in pediatric acute lymphoblastic leukemia: RAS mutations and prednisolone resistance.

Haematologica 2015 Apr 5;100(4):e132-6. Epub 2014 Dec 5.

Department of Pediatric Oncology/Hematology, Erasmus Medical Center-Sophia Children's Hospital, Rotterdam Individualized Therapies for Children with Cancer Study Group Dutch Childhood Oncology Group, The Hague, The Netherlands

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http://dx.doi.org/10.3324/haematol.2014.112995DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380734PMC
April 2015