Rivelilson Mendes de Freitas

Rivelilson Mendes de Freitas

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Rivelilson Mendes de Freitas

Publications by authors named "Rivelilson Mendes de Freitas"

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Effects of isopentyl ferulate on oxidative stress biomarkers and a possible GABAergic anxiolytic-like trait in Swiss mice.

Chem Biol Interact 2018 Jun 20;289:119-128. Epub 2018 Mar 20.

Postgraduate Program in Pharmacology, Federal University of Piauí, Teresina, Piauí, 64.049-550, Brazil; Laboratory of Research in Experimental Neurochemistry of Postgraduate Program in Pharmaceutical Sciences, Federal University of Piauí, Teresina, Piauí, 64.049-550, Brazil.

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http://dx.doi.org/10.1016/j.cbi.2018.03.009DOI Listing
June 2018

Phytol a Natural Diterpenoid with Pharmacological Applications on Central Nervous System: A Review.

Recent Pat Biotechnol 2014 ;8(3):194-205

Laboratory of Research in Experimental Neurochemistry of Post- Graduation Program in Biotechnology, CEP 64048-901, Campus Ministro Petronio Portella, Teresina, Piaui, Brazil.

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http://dx.doi.org/10.2174/187220830803150605162745DOI Listing
March 2017

Pre-clinical toxicology of garcinielliptone FC, a tautomeric pair of polyprenylated benzophenone, isolated from Platonia insignis Mart seeds.

Phytomedicine 2016 May 8;23(5):477-82. Epub 2016 Mar 8.

Department of Phamacy, Laboratory of Research in Experimental Neurochemistry (LAPNEX), Federal University of Piauí, Teresina, CEP 64049-550, Piauí, Brazil.

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http://dx.doi.org/10.1016/j.phymed.2016.02.013DOI Listing
May 2016

Diminazene aceturate--An antiparasitic drug of antiquity: Advances in pharmacology & therapeutics.

Pharmacol Res 2015 Dec 22;102:138-57. Epub 2015 Oct 22.

Department of Pharmacy, Federal University of Piauí, Teresina, Piauí 64049-550, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.phrs.2015.10.005DOI Listing
December 2015

The role of flavonoids on oxidative stress in epilepsy.

Oxid Med Cell Longev 2015 11;2015:171756. Epub 2015 Jan 11.

Postgraduate Program in Biotechnology, State University of Feira de Santana, 44036-900 Feira de Santana, BA, Brazil ; Federal University of San Francisco Valley, 56304-205 Petrolina, PE, Brazil.

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http://dx.doi.org/10.1155/2015/171756DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306219PMC
October 2015

Phytol in a pharma-medico-stance.

Chem Biol Interact 2015 Oct 19;240:60-73. Epub 2015 Aug 19.

Department of Biochemistry and Pharmacology, Post-graduation Program in Pharmaceutical Science, Federal University of Piauí, 64.049-550 Teresina, Brazil.

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http://dx.doi.org/10.1016/j.cbi.2015.07.010DOI Listing
October 2015

In vivo evaluation of anticonvulsant and antioxidant effects of phenobarbital microemulsion for transdermal administration in pilocarpine seizure rat model.

Pharmacol Biochem Behav 2015 Apr 22;131:6-12. Epub 2015 Jan 22.

Laboratory of Experimental Neurochemistry Research, Federal University of Piauí, Teresina, PI, Brazil; College of Pharmacy, Federal University of Piauí, Campus Minister Petronio Portela, Teresina, PI, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.pbb.2015.01.008DOI Listing
April 2015

Evaluation of p-cymene, a natural antioxidant.

Pharm Biol 2015 Mar 4;53(3):423-8. Epub 2014 Dec 4.

Department of Biochemistry and Pharmacology, Laboratory of Research in Experimental Neurochemistry of Post-Graduation Program in Pharmaceutics Science , Federal University of Piauí, Teresina - Piauí , Brazil and.

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http://dx.doi.org/10.3109/13880209.2014.923003DOI Listing
March 2015

Spectroscopic studies on the in vitro antioxidant capacity of isopentyl ferulate.

Chem Biol Interact 2015 Jan 21;225:47-53. Epub 2014 Nov 21.

Post-Graduation Program in Pharmacology, Federal University of Piauí, CEP 64.049-550 Teresina, Piauí, Brazil; Laboratory of Research in Experimental Neurochemistry of Post-Graduation Program in Pharmaceutical Sciences, Federal University of Piauí, CEP 64.049-550 Teresina, Piauí, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.cbi.2014.11.008DOI Listing
January 2015

Behavioral tests and oxidative stress evaluation in mitochondria isolated from the brain and liver of mice treated with riparin A.

Life Sci 2015 Jan 2;121:57-64. Epub 2014 Dec 2.

Laboratory for Research in Experimental Neurochemistry, Campus Ministro Petrônio Portella, Federal University of Piauí, Teresina, PI 64049550, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.lfs.2014.11.018DOI Listing
January 2015

Neuropharmacological effects of carvacryl acetate on δ-aminolevulinic dehydratase, Na+, K+-ATPase activities and amino acids levels in mice hippocampus after seizures.

Chem Biol Interact 2015 Jan 6;226:49-57. Epub 2014 Dec 6.

Postgraduate Program of Pharmacology, Federal University of Piauí, Teresina, PI, Brazil; Department of Biochemistry and Pharmacology, Laboratory of Experimental Neurochemistry Research, Center of Pharmaceutical Technology, Federal University of Piauí, Teresina, PI, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.cbi.2014.12.001DOI Listing
January 2015

Anticonvulsant effects of acute treatment with cyane-carvone at repeated oral doses in epilepsy models.

Pharmacol Biochem Behav 2014 Sep 23;124:421-4. Epub 2014 Jun 23.

Laboratory of Experimental Neurochemistry Research, Federal University of Piauí (UFPI), Campus Ministro Petrônio Portella, Ininga District, Teresina, Piauí, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.pbb.2014.06.016DOI Listing
September 2014

Anxiolytic-like effects and mechanism of (-)-myrtenol: a monoterpene alcohol.

Neurosci Lett 2014 Sep 12;579:119-24. Epub 2014 Jul 12.

Postgraduate Program in Biotechnology (PgRENORBIO), Federal University of Paraíba, João Pessoa, PB, Brazil; Postgraduate Program in Natural Products and Bioactive Synthetics (PgPNSB), Federal University of Paraíba, João Pessoa, PB, Brazil.

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http://dx.doi.org/10.1016/j.neulet.2014.07.007DOI Listing
September 2014

Cyane-carvone, a synthetic derivative of carvone, inhibits inflammatory response by reducing cytokine production and oxidative stress and shows antinociceptive effect in mice.

Inflammation 2014 Jun;37(3):966-77

Laboratório de Pesquisa em Neuroquímica Experimental, Curso de Farmácia, Universidade Federal do Piauí, Campus Universitário Ministro Petrônio Portella, Bairro Ininga, 64049-550, Teresina, Piauí, Brazil.

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http://dx.doi.org/10.1007/s10753-014-9817-1DOI Listing
June 2014

Potential antioxidant and anxiolytic effects of (+)-limonene epoxide in mice after marble-burying test.

Pharmacol Biochem Behav 2014 Mar 24;118:69-78. Epub 2014 Jan 24.

Post-Graduate in Biotechnology of Northeast Biotechnology Network, Federal University of Piauí, CEP 64048-901 Teresina, Piauí, Brazil.

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http://dx.doi.org/10.1016/j.pbb.2014.01.006DOI Listing
March 2014

Anxiolytic-like effects of phytol: possible involvement of GABAergic transmission.

Brain Res 2014 Feb 10;1547:34-42. Epub 2013 Dec 10.

Laboratory of Research in Experimental Neurochemistry of Post-Graduation Program in Pharmaceutics Science, Federal University of Piauí, 64.049-550 Teresina, Piauí, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.brainres.2013.12.003DOI Listing
February 2014

Development and evaluation of liposomal formulation containing nimodipine on anxiolytic activity in mice.

Pharmacol Biochem Behav 2014 Jan 4;116:64-8. Epub 2013 Nov 4.

Laboratory of Experimental Neurochemistry Research, Federal University of Piaui, Teresina, PI, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.pbb.2013.10.023DOI Listing
January 2014

Anxiolytic-like effects of carvacryl acetate, a derivative of carvacrol, in mice.

Pharmacol Biochem Behav 2013 Nov 12;112:42-8. Epub 2013 Sep 12.

Postgraduate Program of Pharmacology, Federal University of Piauí, Teresina, Piauí, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.pbb.2013.09.001DOI Listing
November 2013

Antioxidant effects of nerolidol in mice hippocampus after open field test.

Neurochem Res 2013 Sep 14;38(9):1861-70. Epub 2013 Jun 14.

Postgraduate Program in Pharmacology, Federal University of Piauí, Teresina, Piauí, 64049-550, Brazil.

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http://dx.doi.org/10.1007/s11064-013-1092-2DOI Listing
September 2013

The systems containing clays and clay minerals from modified drug release: a review.

Colloids Surf B Biointerfaces 2013 Mar 20;103:642-51. Epub 2012 Nov 20.

Programa de Pós-Graduação em Ciências Farmacêuticas, Centro de Ciências da Saúde, Universidade Federal do Piauí, Teresina, PI, CEP 64049-550, Brazil.

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http://dx.doi.org/10.1016/j.colsurfb.2012.10.068DOI Listing
March 2013

Anthelmintic activity of carvacryl acetate against Schistosoma mansoni.

Parasitol Res 2013 Feb 21;112(2):603-10. Epub 2012 Oct 21.

Parasitology Laboratory, Butantan Institute, Avenida Vital Brasil 1500, 05503-900 São Paulo, SP, Brazil.

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http://dx.doi.org/10.1007/s00436-012-3172-7DOI Listing
February 2013

Anticonvulsant and antioxidant effects of cyano-carvone and its action on acetylcholinesterase activity in mice hippocampus.

Cell Mol Neurobiol 2012 May 29;32(4):633-40. Epub 2012 Feb 29.

Laboratory of Research in Experimental Neurochemistry of Post-Graduation Program in Pharmaceutics Science, Federal University of Piauí, Teresina, Piauí, Brazil.

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http://dx.doi.org/10.1007/s10571-012-9812-8DOI Listing
May 2012

Superoxide dismutase and catalase activities in rat hippocampus pretreated with garcinielliptone FC from Platonia insignis.

Pharm Biol 2012 Apr 1;50(4):453-7. Epub 2011 Dec 1.

Laboratory of Genetic Toxicology, Post-Graduation Program in Genetic and Applied Toxicology, Lutheran University of Brazil, Canoas, RS, Brazil.

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http://dx.doi.org/10.3109/13880209.2011.611146DOI Listing
April 2012

Evaluation of acute toxicity of a natural compound (+)-limonene epoxide and its anxiolytic-like action.

Brain Res 2012 Apr 10;1448:56-62. Epub 2012 Feb 10.

Department of Chemistry of Federal University of Piauí, CEP 64.049-550, Teresina, Piauí, Brazil.

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http://dx.doi.org/10.1016/j.brainres.2012.01.070DOI Listing
April 2012

In vitro antimicrobial and brine shrimp lethality of Allophylus cobbe L.

Ayu 2012 Apr;33(2):299-302

Lecturer, Department of Pharmacy, Faculty of Science and Engineering, Southern University Bangladesh, Chittagong, Bangladesh.

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http://dx.doi.org/10.4103/0974-8520.105256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3611656PMC
April 2012

Evaluation of possible antioxidant and anticonvulsant effects of the ethyl acetate fraction from Platonia insignis Mart. (Bacuri) on epilepsy models.

Epilepsy Behav 2011 Dec 4;22(4):678-84. Epub 2011 Nov 4.

Laboratory of Genetic Toxicology, Postgraduate Program in Genetic and Applied Toxicology, Lutheran University of Brazil, Canoas, RS, Brazil.

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http://dx.doi.org/10.1016/j.yebeh.2011.09.021DOI Listing
December 2011

Lipoic acid effects on glutamate and taurine concentrations in rat hippocampus after pilocarpine-induced seizures.

Arq Neuropsiquiatr 2011 ;69(2B):360-4

Programa de Pós-Graduação em Ciências Farmacêuticas, Núcleo de Tecnologia Farmacêutica, Laboratório de Pesquisa em Neuroquímica Experimental, Universidade Federal do Piauí, Teresina, PI, Brazil.

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http://dx.doi.org/10.1590/s0004-282x2011000300018DOI Listing
November 2011

Antioxidant and antinociceptive effects of Citrus limon essential oil in mice.

J Biomed Biotechnol 2011 31;2011:678673. Epub 2011 May 31.

Departmento de Bioquímica e Farmacologia, Programa de Pós-Graduação em Ciências Farmacêuticas, Laboratório de Pesquisa em Neuroquímica Experimental, Núcleo de Tecnologia Farmacêutica, Universidade Federal do Piauí, Teresina, PI 64049-550, Brazil.

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http://dx.doi.org/10.1155/2011/678673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110330PMC
October 2011

Oxidative stress in rat striatum after pilocarpine-induced seizures is diminished by alpha-tocopherol.

Eur J Pharmacol 2011 Oct 4;668(1-2):65-71. Epub 2011 Jul 4.

Laboratory of Research in Experimental Neurochemistry of Post-Graduation Program in Pharmaceutics Science, Federal University of Piaui, CEP 64.049-550, Teresina, Piaui, Brazil.

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http://dx.doi.org/10.1016/j.ejphar.2011.06.035DOI Listing
October 2011

Lipoic acid alters amino acid neurotransmitters content in rat hippocampus after pilocarpine-induced seizures.

Fundam Clin Pharmacol 2011 Aug 15;25(4):485-92. Epub 2010 Jul 15.

Laboratory of Experimental Research in Biological Sciences of Federal University of Piauí, Piauí, Brazil.

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http://doi.wiley.com/10.1111/j.1472-8206.2010.00862.x
Publisher Site
http://dx.doi.org/10.1111/j.1472-8206.2010.00862.xDOI Listing
August 2011

Antioxidant activity of Citrus limon essential oil in mouse hippocampus.

Pharm Biol 2011 Jul;49(7):709-15

Laboratory of Research in Experimental Neurochemistry of Federal University of Piaui, Teresina, Piaui, Brazil.

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http://dx.doi.org/10.3109/13880209.2010.541924DOI Listing
July 2011

Caffeic acid effects on oxidative stress in rat hippocampus after pilocarpine-induced seizures.

Neurol Sci 2011 Jun 1;32(3):375-80. Epub 2010 Oct 1.

Laboratory of Research in Experimental Neurochemistry, Curso de Farmácia, Centro de Ciências da Saúde, Federal University of Piaui, Campus Universitário Ministro Petrônio Portella, Bairro Ininga, Teresina, PI 64049-550, Brazil.

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http://dx.doi.org/10.1007/s10072-010-0420-4DOI Listing
June 2011

Neuropharmacological effects of lipoic acid and ubiquinone on δ-aminolevulinic dehydratase, Na(+) , K(+) -ATPase, and Mg(2+) -ATPase activities in rat hippocampus after pilocarpine-induced seizures.

Fundam Clin Pharmacol 2011 Apr;25(2):211-6

Laboratory of Physiology and Pharmacology, Federal University of Piauí, Rua Cícero Eduardo, s/n, Junco, Cep: 64.600-000, Picos, Piauí, Brazil.

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http://dx.doi.org/10.1111/j.1472-8206.2010.00841.xDOI Listing
April 2011

Evaluation of central nervous system effects of iso-6-cassine isolated from Senna spectabilis var. excelsa (Schrad) in mice.

Fitoterapia 2011 Mar 19;82(2):255-9. Epub 2010 Oct 19.

Laboratório de Produtos Naturais do Departamento de Química, Universidade Federal do Ceará, Fortaleza, Ceará, Brazil.

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http://dx.doi.org/10.1016/j.fitote.2010.10.007DOI Listing
March 2011

Lipoic acid inhibits caspase-dependent and -independent cell death pathways and is neuroprotective against hippocampal damage after pilocarpine-induced seizures.

Pharmacol Biochem Behav 2011 Jan 6;97(3):531-6. Epub 2010 Nov 6.

Laboratory of Research in Experimental Neurochemistry of Federal University of Piaui, Piaui, Brazil.

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http://dx.doi.org/10.1016/j.pbb.2010.11.001DOI Listing
January 2011

Analysis of possible food/nutrient and drug interactions in hospitalized patients.

Einstein (Sao Paulo) 2010 Sep;8(3):298-302

Universidade Federal do Piauí - UFPI, Picos, PI, BR.

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http://dx.doi.org/10.1590/S1679-45082010AO1672DOI Listing
September 2010

Neuronal damage and memory deficits after seizures are reversed by ascorbic acid?

Arq Neuropsiquiatr 2010 Aug;68(4):579-85

Laboratory of Experimental Research in Biological Sciences, Federal University of Piauí, PI, Brazil.

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http://dx.doi.org/10.1590/s0004-282x2010000400019DOI Listing
August 2010

Alterations on monoamines concentration in rat hippocampus produced by lipoic acid.

Arq Neuropsiquiatr 2010 Jun;68(3):362-6

Laboratory of Experimental Research in Biological Sciences, Federal University of Piaui, Picos, PI, Brazil.

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http://dx.doi.org/10.1590/s0004-282x2010000300006DOI Listing
June 2010

Pilocarpine-induced seizures produce alterations on choline acetyltransferase and acetylcholinesterase activities and deficit memory in rats.

Cell Mol Neurobiol 2010 May 26;30(4):569-75. Epub 2009 Nov 26.

Laboratory of Physiology and Pharmacology, Federal University of Piaui, Rua Cícero Eduardo, s/n, Junco, Picos, 64, Piaui, 600-000, Brazil.

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http://dx.doi.org/10.1007/s10571-009-9481-4DOI Listing
May 2010

Lipoic acid alters delta-aminolevulinic dehydratase, glutathione peroxidase and Na+,K+-ATPase activities and glutathione-reduced levels in rat hippocampus after pilocarpine-induced seizures.

Cell Mol Neurobiol 2010 Apr 2;30(3):381-7. Epub 2009 Oct 2.

Laboratory of Physiology and Pharmacology of Federal University of Piauí, Rua Cícero Eduardo, s/n, Junco, Picos, Piauí, 64600-000, Brazil.

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http://dx.doi.org/10.1007/s10571-009-9460-9DOI Listing
April 2010

Lipoic acid blocks seizures induced by pilocarpine via increases in delta-aminolevulinic dehydratase and Na+, K+-ATPase activity in rat brain.

Pharmacol Biochem Behav 2010 Mar 21;95(1):88-91. Epub 2009 Dec 21.

Laboratory of Experimental Research in Biological Sciences of Federal University of Piauí, Piauí, Brazil.

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http://dx.doi.org/10.1016/j.pbb.2009.12.011DOI Listing
March 2010

Lipoic Acid increases hippocampal choline acetyltransferase and acetylcholinesterase activities and improvement memory in epileptic rats.

Neurochem Res 2010 Jan 11;35(1):162-70. Epub 2009 Aug 11.

Laboratory of Physiology and Pharmacology, Federal University of Piaui, Junco, Picos, Piaui 64.600-000, Brazil.

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http://dx.doi.org/10.1007/s11064-009-0041-6DOI Listing
January 2010

Effects of lipoic acid on oxidative stress in rat striatum after pilocarpine-induced seizures.

Neurochem Int 2010 Jan 26;56(1):16-20. Epub 2009 Aug 26.

Laboratory of Physiology and Pharmacology, Federal University of Piaui, Picos, Piauí, Brazil.

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http://dx.doi.org/10.1016/j.neuint.2009.08.009DOI Listing
January 2010

Neurochemical changes on oxidative stress in rat hippocampus during acute phase of pilocarpine-induced seizures.

Pharmacol Biochem Behav 2010 Jan 1;94(3):341-5. Epub 2009 Oct 1.

Laboratory of Physiology and Pharmacology of Federal University of Piaui, Rua Cícero Eduardo, s/n, Junco, 64.600-000, Picos, Piaui, Brazil.

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https://linkinghub.elsevier.com/retrieve/pii/S00913057090028
Publisher Site
http://dx.doi.org/10.1016/j.pbb.2009.09.015DOI Listing
January 2010

Modifications in muscarinic, dopaminergic and serotonergic receptors concentrations in the hippocampus and striatum of epileptic rats.

Life Sci 2005 Dec 30;78(3):253-8. Epub 2005 Aug 30.

Department of Physiology and Pharmacology, Laboratory of Neuropharmacology, School of Medicine, Federal University of Ceará, Rua Cel. Nunes de Melo 1127, Fortaleza 60431-970, CE, Brazil.

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http://dx.doi.org/10.1016/j.lfs.2005.04.045DOI Listing
December 2005