Ritu Roy

Human pediatric B-cell acute lymphoblastic leukemias can be classified as B-1 or B-2-like based on a minimal transcriptional signature.

Authors:

Briana Fitch Ritu Roy Huimin Geng Encarnacion Montecino-Rodriguez Henrik Bengtsson Coline Gaillard Kamir Hiam David Casero Adam B Olshen Kenneth Dorshkind Scott C Kogan

Exp Hematol 2020 10 15;90:65-71.e1. Epub 2020 Sep 15.

Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA. Electronic address:

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October 2020

Next-Generation Sequencing of Retinoblastoma Identifies Pathogenic Alterations beyond RB1 Inactivation That Correlate with Aggressive Histopathologic Features.

Authors:

Armin R Afshar Melike Pekmezci Michele M Bloomer Nicola J Cadenas Meredith Stevers Anuradha Banerjee Ritu Roy Adam B Olshen Jessica Van Ziffle Courtney Onodera W Patrick Devine James P Grenert Boris C Bastian David A Solomon Bertil E Damato

Ophthalmology 2020 06 12;127(6):804-813. Epub 2019 Dec 12.

Department of Ophthalmology, University of California, San Francisco, San Francisco, California; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom.

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June 2020

Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age.

Authors:

Simon Kebede Merid Alexei Novoloaca Gemma C Sharp Leanne K Küpers Alvin T Kho Ritu Roy Lu Gao Isabella Annesi-Maesano Pooja Jain Michelle Plusquin Manolis Kogevinas Catherine Allard Florianne O Vehmeijer Nabila Kazmi Lucas A Salas Faisal I Rezwan Hongmei Zhang Sylvain Sebert Darina Czamara Sheryl L Rifas-Shiman Phillip E Melton Debbie A Lawlor Göran Pershagen Carrie V Breton Karen Huen Nour Baiz Luigi Gagliardi Tim S Nawrot Eva Corpeleijn Patrice Perron Liesbeth Duijts Ellen Aagaard Nohr Mariona Bustamante Susan L Ewart Wilfried Karmaus Shanshan Zhao Christian M Page Zdenko Herceg Marjo-Riitta Jarvelin Jari Lahti Andrea A Baccarelli Denise Anderson Priyadarshini Kachroo Caroline L Relton Anna Bergström Brenda Eskenazi Munawar Hussain Soomro Paolo Vineis Harold Snieder Luigi Bouchard Vincent W Jaddoe Thorkild I A Sørensen Martine Vrijheid S Hasan Arshad John W Holloway Siri E Håberg Per Magnus Terence Dwyer Elisabeth B Binder Dawn L DeMeo Judith M Vonk John Newnham Kelan G Tantisira Inger Kull Joseph L Wiemels Barbara Heude Jordi Sunyer Wenche Nystad Monica C Munthe-Kaas Katri Räikkönen Emily Oken Rae-Chi Huang Scott T Weiss Josep Maria Antó Jean Bousquet Ashish Kumar Cilla Söderhäll Catarina Almqvist Andres Cardenas Olena Gruzieva Cheng-Jian Xu Sarah E Reese Juha Kere Petter Brodin Olivia Solomon Matthias Wielscher Nina Holland Akram Ghantous Marie-France Hivert Janine F Felix Gerard H Koppelman Stephanie J London Erik Melén

Genome Med 2020 03 2;12(1):25. Epub 2020 Mar 2.

Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

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March 2020

Glucocorticoids paradoxically facilitate steroid resistance in T cell acute lymphoblastic leukemias and thymocytes.

Authors:

Lauren K Meyer Benjamin J Huang Cristina Delgado-Martin Ritu P Roy Aaron Hechmer Anica M Wandler Tiffaney L Vincent Paolo Fortina Adam B Olshen Brent L Wood Terzah M Horton Kevin M Shannon David T Teachey Michelle L Hermiston

J Clin Invest 2020 02;130(2):863-876

Department of Pediatrics, UCSF, San Francisco, California, USA.

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February 2020

Next-Generation Sequencing of Uveal Melanoma for Detection of Genetic Alterations Predicting Metastasis.

Authors:

Armin R Afshar Bertil E Damato Jay M Stewart Lydia B Zablotska Ritu Roy Adam B Olshen Nancy M Joseph Boris C Bastian

Transl Vis Sci Technol 2019 Mar 17;8(2):18. Epub 2019 Apr 17.

Hellen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA.

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March 2019

Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight.

Authors:

Leanne K Küpers Claire Monnereau Gemma C Sharp Paul Yousefi Lucas A Salas Akram Ghantous Christian M Page Sarah E Reese Allen J Wilcox Darina Czamara Anne P Starling Alexei Novoloaca Samantha Lent Ritu Roy Cathrine Hoyo Carrie V Breton Catherine Allard Allan C Just Kelly M Bakulski John W Holloway Todd M Everson Cheng-Jian Xu Rae-Chi Huang Diana A van der Plaat Matthias Wielscher Simon Kebede Merid Vilhelmina Ullemar Faisal I Rezwan Jari Lahti Jenny van Dongen Sabine A S Langie Tom G Richardson Maria C Magnus Ellen A Nohr Zongli Xu Liesbeth Duijts Shanshan Zhao Weiming Zhang Michelle Plusquin Dawn L DeMeo Olivia Solomon Joosje H Heimovaara Dereje D Jima Lu Gao Mariona Bustamante Patrice Perron Robert O Wright Irva Hertz-Picciotto Hongmei Zhang Margaret R Karagas Ulrike Gehring Carmen J Marsit Lawrence J Beilin Judith M Vonk Marjo-Riitta Jarvelin Anna Bergström Anne K Örtqvist Susan Ewart Pia M Villa Sophie E Moore Gonneke Willemsen Arnout R L Standaert Siri E Håberg Thorkild I A Sørensen Jack A Taylor Katri Räikkönen Ivana V Yang Katerina Kechris Tim S Nawrot Matt J Silver Yun Yun Gong Lorenzo Richiardi Manolis Kogevinas Augusto A Litonjua Brenda Eskenazi Karen Huen Hamdi Mbarek Rachel L Maguire Terence Dwyer Martine Vrijheid Luigi Bouchard Andrea A Baccarelli Lisa A Croen Wilfried Karmaus Denise Anderson Maaike de Vries Sylvain Sebert Juha Kere Robert Karlsson Syed Hasan Arshad Esa Hämäläinen Michael N Routledge Dorret I Boomsma Andrew P Feinberg Craig J Newschaffer Eva Govarts Matthieu Moisse M Daniele Fallin Erik Melén Andrew M Prentice Eero Kajantie Catarina Almqvist Emily Oken Dana Dabelea H Marike Boezen Phillip E Melton Rosalind J Wright Gerard H Koppelman Letizia Trevisi Marie-France Hivert Jordi Sunyer Monica C Munthe-Kaas Susan K Murphy Eva Corpeleijn Joseph Wiemels Nina Holland Zdenko Herceg Elisabeth B Binder George Davey Smith Vincent W V Jaddoe Rolv T Lie Wenche Nystad Stephanie J London Debbie A Lawlor Caroline L Relton Harold Snieder Janine F Felix

Nat Commun 2019 04 23;10(1):1893. Epub 2019 Apr 23.

The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

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April 2019

Epigenomic profiling of newborns with isolated orofacial clefts reveals widespread DNA methylation changes and implicates metastable epiallele regions in disease risk.

Authors:

Semira Gonseth Gary M Shaw Ritu Roy Mark R Segal Kripa Asrani Jasper Rine Joseph Wiemels Nicholas J Marini

Epigenetics 2019 02 14;14(2):198-213. Epub 2019 Mar 14.

f California Institute for Quantitative Biosciences , University of California , Berkeley , CA , USA.

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February 2019

Autocrine TGFβ Is a Survival Factor for Monocytes and Drives Immunosuppressive Lineage Commitment.

Authors:

Alba Gonzalez-Junca Kyla E Driscoll Ilenia Pellicciotta Shisuo Du Chen Hao Lo Ritu Roy Renate Parry Iliana Tenvooren Diana M Marquez Matthew H Spitzer Mary Helen Barcellos-Hoff

Cancer Immunol Res 2019 02 11;7(2):306-320. Epub 2018 Dec 11.

Department of Radiation Oncology, University of California San Francisco, San Francisco, California.

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February 2019

Genomic and expression profiling reveal molecular heterogeneity of disseminated tumor cells in bone marrow of early breast cancer.

Authors:

Mark Jesus M Magbanua Hope S Rugo Louai Hauranieh Ritu Roy Janet H Scott Jen Chieh Lee Feng Hsiao Eduardo V Sosa Laura Van't Veer Laura J Esserman John W Park

NPJ Breast Cancer 2018 5;4:31. Epub 2018 Sep 5.

1Division of Hematology/Oncology, University of California, San Francisco, San Francisco, CA USA.

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September 2018

Replication confers β cell immaturity.

Authors:

Sapna Puri Nilotpal Roy Holger A Russ Laura Leonhardt Esra K French Ritu Roy Henrik Bengtsson Donald K Scott Andrew F Stewart Matthias Hebrok

Nat Commun 2018 02 2;9(1):485. Epub 2018 Feb 2.

Diabetes Center, Department of Medicine, University of California, San Francisco, CA, USA.

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February 2018

Expanded Genomic Profiling of Circulating Tumor Cells in Metastatic Breast Cancer Patients to Assess Biomarker Status and Biology Over Time (CALGB 40502 and CALGB 40503, Alliance).

Authors:

Mark Jesus M Magbanua Hope S Rugo Denise M Wolf Louai Hauranieh Ritu Roy Praveen Pendyala Eduardo V Sosa Janet H Scott Jin Sun Lee Brandelyn Pitcher Terry Hyslop William T Barry Steven J Isakoff Maura Dickler Laura Van't Veer John W Park

Clin Cancer Res 2018 03 8;24(6):1486-1499. Epub 2018 Jan 8.

Division of Hematology/Oncology, University of California at San Francisco, San Francisco, California.

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March 2018

Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium.

Authors:

Janine F Felix Bonnie R Joubert Andrea A Baccarelli Gemma C Sharp Catarina Almqvist Isabella Annesi-Maesano Hasan Arshad Nour Baïz Marian J Bakermans-Kranenburg Kelly M Bakulski Elisabeth B Binder Luigi Bouchard Carrie V Breton Bert Brunekreef Kelly J Brunst Esteban G Burchard Mariona Bustamante Leda Chatzi Monica Cheng Munthe-Kaas Eva Corpeleijn Darina Czamara Dana Dabelea George Davey Smith Patrick De Boever Liesbeth Duijts Terence Dwyer Celeste Eng Brenda Eskenazi Todd M Everson Fahimeh Falahi M Daniele Fallin Sara Farchi Mariana F Fernandez Lu Gao Tom R Gaunt Akram Ghantous Matthew W Gillman Semira Gonseth Veit Grote Olena Gruzieva Siri E Håberg Zdenko Herceg Marie-France Hivert Nina Holland John W Holloway Cathrine Hoyo Donglei Hu Rae-Chi Huang Karen Huen Marjo-Riitta Järvelin Dereje D Jima Allan C Just Margaret R Karagas Robert Karlsson Wilfried Karmaus Katerina J Kechris Juha Kere Manolis Kogevinas Berthold Koletzko Gerard H Koppelman Leanne K Küpers Christine Ladd-Acosta Jari Lahti Nathalie Lambrechts Sabine A S Langie Rolv T Lie Andrew H Liu Maria C Magnus Per Magnus Rachel L Maguire Carmen J Marsit Wendy McArdle Erik Melén Phillip Melton Susan K Murphy Tim S Nawrot Lorenza Nisticò Ellen A Nohr Björn Nordlund Wenche Nystad Sam S Oh Emily Oken Christian M Page Patrice Perron Göran Pershagen Costanza Pizzi Michelle Plusquin Katri Raikkonen Sarah E Reese Eva Reischl Lorenzo Richiardi Susan Ring Ritu P Roy Peter Rzehak Greet Schoeters David A Schwartz Sylvain Sebert Harold Snieder Thorkild I A Sørensen Anne P Starling Jordi Sunyer Jack A Taylor Henning Tiemeier Vilhelmina Ullemar Marina Vafeiadi Marinus H Van Ijzendoorn Judith M Vonk Annette Vriens Martine Vrijheid Pei Wang Joseph L Wiemels Allen J Wilcox Rosalind J Wright Cheng-Jian Xu Zongli Xu Ivana V Yang Paul Yousefi Hongmei Zhang Weiming Zhang Shanshan Zhao Golareh Agha Caroline L Relton Vincent W V Jaddoe Stephanie J London

Int J Epidemiol 2018 02;47(1):22-23u

National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, USA.

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February 2018

Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: findings from the pregnancy and childhood epigenetics (PACE) consortium.

Authors:

Gemma C Sharp Lucas A Salas Claire Monnereau Catherine Allard Paul Yousefi Todd M Everson Jon Bohlin Zongli Xu Rae-Chi Huang Sarah E Reese Cheng-Jian Xu Nour Baïz Cathrine Hoyo Golareh Agha Ritu Roy John W Holloway Akram Ghantous Simon K Merid Kelly M Bakulski Leanne K Küpers Hongmei Zhang Rebecca C Richmond Christian M Page Liesbeth Duijts Rolv T Lie Phillip E Melton Judith M Vonk Ellen A Nohr ClarLynda Williams-DeVane Karen Huen Sheryl L Rifas-Shiman Carlos Ruiz-Arenas Semira Gonseth Faisal I Rezwan Zdenko Herceg Sandra Ekström Lisa Croen Fahimeh Falahi Patrice Perron Margaret R Karagas Bilal M Quraishi Matthew Suderman Maria C Magnus Vincent W V Jaddoe Jack A Taylor Denise Anderson Shanshan Zhao Henriette A Smit Michele J Josey Asa Bradman Andrea A Baccarelli Mariona Bustamante Siri E Håberg Göran Pershagen Irva Hertz-Picciotto Craig Newschaffer Eva Corpeleijn Luigi Bouchard Debbie A Lawlor Rachel L Maguire Lisa F Barcellos George Davey Smith Brenda Eskenazi Wilfried Karmaus Carmen J Marsit Marie-France Hivert Harold Snieder M Daniele Fallin Erik Melén Monica C Munthe-Kaas Hasan Arshad Joseph L Wiemels Isabella Annesi-Maesano Martine Vrijheid Emily Oken Nina Holland Susan K Murphy Thorkild I A Sørensen Gerard H Koppelman John P Newnham Allen J Wilcox Wenche Nystad Stephanie J London Janine F Felix Caroline L Relton

Hum Mol Genet 2017 10;26(20):4067-4085

MRC Integrative Epidemiology Unit.

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October 2017

Characterization of Metabolic, Diffusion, and Perfusion Properties in GBM: Contrast-Enhancing versus Non-Enhancing Tumor.

Authors:

Adam Autry Joanna J Phillips Stojan Maleschlijski Ritu Roy Annette M Molinaro Susan M Chang Soonmee Cha Janine M Lupo Sarah J Nelson

Transl Oncol 2017 Dec 22;10(6):895-903. Epub 2017 Sep 22.

Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, USA; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA, USA.

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December 2017

Correlates of Prenatal and Early-Life Tobacco Smoke Exposure and Frequency of Common Gene Deletions in Childhood Acute Lymphoblastic Leukemia.

Authors:

Adam J de Smith Maneet Kaur Semira Gonseth Alyson Endicott Steve Selvin Luoping Zhang Ritu Roy Xiaorong Shao Helen M Hansen Alice Y Kang Kyle M Walsh Gary V Dahl Roberta McKean-Cowdin Catherine Metayer Joseph L Wiemels

Cancer Res 2017 04 15;77(7):1674-1683. Epub 2017 Feb 15.

Department of Epidemiology and Biostatistics, Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, California.

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April 2017

Immunomethylomic approach to explore the blood neutrophil lymphocyte ratio (NLR) in glioma survival.

Authors:

John K Wiencke Devin C Koestler Lucas A Salas Joseph L Wiemels Ritu P Roy Helen M Hansen Terri Rice Lucie S McCoy Paige M Bracci Annette M Molinaro Karl T Kelsey Margaret R Wrensch Brock C Christensen

Clin Epigenetics 2017 2;9:10. Epub 2017 Feb 2.

Departments of Epidemiology, Pharmacology & Toxicology, and Community and Family Medicine, Geisel School of Medicine at Dartmouth College, Lebanon, NH 03756 USA.

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December 2017

Serial analysis of 3D H-1 MRSI for patients with newly diagnosed GBM treated with combination therapy that includes bevacizumab.

Authors:

Sarah J Nelson Yan Li Janine M Lupo Marram Olson Jason C Crane Annette Molinaro Ritu Roy Jennifer Clarke Nicholas Butowski Michael Prados Soonmee Cha Susan M Chang

J Neurooncol 2016 10 17;130(1):171-179. Epub 2016 Aug 17.

Department of Neurological Surgery, University of California, San Francisco, CA, USA.

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October 2016

Association of early changes in 1H MRSI parameters with survival for patients with newly diagnosed glioblastoma receiving a multimodality treatment regimen.

Authors:

Sarah J Nelson Achuta K Kadambi Ilwoo Park Yan Li Jason Crane Marram Olson Annette Molinaro Ritu Roy Nicholas Butowski Soonmee Cha Susan Chang

Neuro Oncol 2017 03;19(3):430-439

Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California.

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March 2017

Genetic contribution to variation in DNA methylation at maternal smoking-sensitive loci in exposed neonates.

Authors:

Semira Gonseth Adam J de Smith Ritu Roy Mi Zhou Seung-Tae Lee Xiaorong Shao Juhi Ohja Margaret R Wrensch Kyle M Walsh Catherine Metayer Joseph L Wiemels

Epigenetics 2016 09 12;11(9):664-673. Epub 2016 Jul 12.

b The Center for Integrative Research on Childhood Leukemia and the Environment, University of California, Berkeley , Berkeley , CA , USA.

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September 2016

An improved CTC isolation scheme for pairing with downstream genomics: Demonstrating clinical utility in metastatic prostate, lung and pancreatic cancer.

Authors:

Gayatri Premasekharan Elizabeth Gilbert Ross A Okimoto Ashiya Hamirani Karla J Lindquist Vy T Ngo Ritu Roy Jeffrey Hough Matthew Edwards Rosa Paz Adam Foye Riddhi Sood Kirsten A Copren Matthew Gubens Eric J Small Trever G Bivona Eric A Collisson Terence W Friedlander Pamela L Paris

Cancer Lett 2016 09 22;380(1):144-52. Epub 2016 Jun 22.

Department of Urology, University of California, San Francisco (UCSF), San Francisco, CA, USA; Division of Hematology & Oncology, University of California, San Francisco (UCSF), San Francisco, CA, USA. Electronic address:

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September 2016

Association of Diffusion and Anatomic Imaging Parameters with Survival for Patients with Newly Diagnosed Glioblastoma Participating in Two Different Clinical Trials.

Authors:

Qiuting Wen Laleh Jalilian Janine M Lupo Yan Li Ritu Roy Annette M Molinaro Susan M Chang Michael Prados Nicholas Butowski Jennifer Clarke Sarah J Nelson

Transl Oncol 2015 Dec;8(6):446-55

Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA United States; UCSF/UCB Joint Graduate Group in Bioengineering, University of California, San Francisco, San Francisco, CA United States; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA United States. Electronic address:

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December 2015

Periconceptional folate consumption is associated with neonatal DNA methylation modifications in neural crest regulatory and cancer development genes.

Authors:

Semira Gonseth Ritu Roy E Andres Houseman Adam J de Smith Mi Zhou Seung-Tae Lee Sébastien Nusslé Amanda W Singer Margaret R Wrensch Catherine Metayer Joseph L Wiemels

Epigenetics 2015 ;10(12):1166-76

a Department of Epidemiology and Biostatistics ; Laboratory for Molecular Epidemiology; University of California ; San Francisco , CA , USA.

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November 2016

Associations between circulating carotenoids, genomic instability and the risk of high-grade prostate cancer.

Authors:

Tobias Nordström Erin L Van Blarigan Vy Ngo Ritu Roy Vivian Weinberg Xiaoling Song Jeffry Simko Peter R Carroll June M Chan Pamela L Paris

Prostate 2016 Mar 20;76(4):339-48. Epub 2015 Nov 20.

Department of Urology, Helen Diller Family Comprehensive Cancer Research Center, University of California, San Francisco, California.

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March 2016

Genome-wide copy number analysis of cerebrospinal fluid tumor cells and their corresponding archival primary tumors.

Authors:

Mark Jesus M Magbanua Ritu Roy Eduardo V Sosa Louai Hauranieh Andrea Kablanian Lauren E Eisenbud Artem Ryazantsev Alfred Au Janet H Scott Michelle Melisko John W Park

Genom Data 2014 Dec 18;2:60-2. Epub 2014 Apr 18.

Division of Hematology/Oncology, University of California San Francisco, San Francisco, CA, USA ; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California, USA.

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December 2014

Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway.

Nat Genet 2015 Oct 7;47(10):1194-9. Epub 2015 Sep 7.

Department of Pathology, University of California, San Francisco, San Francisco, California, USA.

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October 2015

Transcription and methylation analyses of preleukemic promyelocytes indicate a dual role for PML/RARA in leukemia initiation.

Authors:

Coline Gaillard Taku A Tokuyasu Galit Rosen Jason Sotzen Adeline Vitaliano-Prunier Ritu Roy Emmanuelle Passegué Hugues de Thé Maria E Figueroa Scott C Kogan

Haematologica 2015 Aug 18;100(8):1064-75. Epub 2015 Jun 18.

Department of Laboratory Medicine, University of California, San Francisco, CA, USA

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August 2015

Epigenetic remodeling in B-cell acute lymphoblastic leukemia occurs in two tracks and employs embryonic stem cell-like signatures.

Authors:

Seung-Tae Lee Marcus O Muench Marina E Fomin Jianqiao Xiao Mi Zhou Adam de Smith José I Martín-Subero Simon Heath E Andres Houseman Ritu Roy Margaret Wrensch John Wiencke Catherine Metayer Joseph L Wiemels

Nucleic Acids Res 2015 Mar 17;43(5):2590-602. Epub 2015 Feb 17.

Department of Epidemiology and Biostatistics, University of California at San Francisco, San Francisco, CA 94158, USA Department of Neurological Surgery, University of California at San Francisco, San Francisco, CA 94158, USA

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March 2015

Genetic variants of Adam17 differentially regulate TGFβ signaling to modify vascular pathology in mice and humans.

Authors:

Kyoko Kawasaki Julia Freimuth Dominique S Meyer Marie M Lee Akiko Tochimoto-Okamoto Michael Benzinou Frederic F Clermont Gloria Wu Ritu Roy Tom G W Letteboer Johannes Kristian Ploos van Amstel Sophie Giraud Sophie Dupuis-Girod Gaeten Lesca Cornelius J J Westermann Robert J Coffey Rosemary J Akhurst

Proc Natl Acad Sci U S A 2014 May 8;111(21):7723-8. Epub 2014 May 8.

Helen Diller Family Comprehensive Cancer Center (HDFCCC) and Department of Anatomy, University of California, San Francisco, CA 94158-9001;Department of Anatomy, andInstitute of Human Genetics, University of California, San Francisco, CA 94143

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May 2014

PTPRG inhibition by DNA methylation and cooperation with RAS gene activation in childhood acute lymphoblastic leukemia.

Authors:

Jianqiao Xiao Seung-Tae Lee Yuanyuan Xiao Xiaomei Ma E Andres Houseman Ling-I Hsu Ritu Roy Margaret Wrensch Adam J de Smith Anand Chokkalingam Patricia Buffler John K Wiencke Joseph L Wiemels

Int J Cancer 2014 Sep 19;135(5):1101-9. Epub 2014 Feb 19.

Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA.

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September 2014

Molecular profiling of tumor cells in cerebrospinal fluid and matched primary tumors from metastatic breast cancer patients with leptomeningeal carcinomatosis.

Authors:

Mark Jesus M Magbanua Michelle Melisko Ritu Roy Eduardo V Sosa Louai Hauranieh Andrea Kablanian Lauren E Eisenbud Artem Ryazantsev Alfred Au Janet H Scott John W Park

Cancer Res 2013 Dec 18;73(23):7134-43. Epub 2013 Oct 18.

Authors' Affiliations: Division of Hematology/Oncology; Helen Diller Family Comprehensive Cancer Center; and Helen Diller Family Comprehensive Cancer Center Computational Biology Core, University of California San Francisco, San Francisco, California.

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December 2013

Florid lobular carcinoma in situ: molecular profiling and comparison to classic lobular carcinoma in situ and pleomorphic lobular carcinoma in situ.

Authors:

Sandra J Shin Aseem Lal Sandy De Vries Junko Suzuki Ritu Roy E Shelley Hwang Stuart J Schnitt Frederic M Waldman Yunn-Yi Chen

Hum Pathol 2013 Oct 25;44(10):1998-2009. Epub 2013 Jun 25.

Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY 10065. Electronic address:

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October 2013

Genomic profiling of isolated circulating tumor cells from metastatic breast cancer patients.

Authors:

Mark Jesus M Magbanua Eduardo V Sosa Ritu Roy Lauren E Eisenbud Janet H Scott Adam Olshen Dan Pinkel Hope S Rugo John W Park

Cancer Res 2013 Jan 7;73(1):30-40. Epub 2012 Nov 7.

Division of Hematology/Oncology, University of California San Francisco, San Francisco, CA 94115, USA.

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January 2013

Diversity of antigen-specific responses induced in vivo with CTLA-4 blockade in prostate cancer patients.

Authors:

Serena S Kwek Vinh Dao Ritu Roy Yafei Hou David Alajajian Jeffrey P Simko Eric J Small Lawrence Fong

J Immunol 2012 Oct 5;189(7):3759-66. Epub 2012 Sep 5.

Division of Hematology/Oncology, Department of Pathology, University of California, San Francisco, San Francisco, CA 94143, USA.

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October 2012

Regulators of skeletal development: a cluster analysis of 206 bone tumors reveals diagnostically useful markers.

Authors:

Andrew E Horvai Ritu Roy Dariusz Borys Richard J O'Donnell

Mod Pathol 2012 Nov 6;25(11):1452-61. Epub 2012 Jul 6.

Department of Pathology, University of California, San Francisco, CA 94115-1656, USA.

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November 2012

Mouse and human strategies identify PTPN14 as a modifier of angiogenesis and hereditary haemorrhagic telangiectasia.

Nat Commun 2012 Jan 10;3:616. Epub 2012 Jan 10.

UCSF Helen Diller Family Comprehensive Cancer Center (HDFCCC), San Francisco, California 94158-9001, USA.

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January 2012

Common structural and epigenetic changes in the genome of castration-resistant prostate cancer.

Authors:

Terence W Friedlander Ritu Roy Scott A Tomlins Vy T Ngo Yasuko Kobayashi Aruna Azameera Mark A Rubin Kenneth J Pienta Arul Chinnaiyan Michael M Ittmann Charles J Ryan Pamela L Paris

Cancer Res 2012 Feb 7;72(3):616-25. Epub 2011 Dec 7.

Division on Genitourinary Medical Oncology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California 94143, USA.

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February 2012

Two distinct routes to oral cancer differing in genome instability and risk for cervical node metastasis.

Authors:

Aditi Bhattacharya Ritu Roy Antoine M Snijders Gregory Hamilton Jesse Paquette Taku Tokuyasu Henrik Bengtsson Richard C K Jordan Adam B Olshen Daniel Pinkel Brian L Schmidt Donna G Albertson

Clin Cancer Res 2011 Nov 8;17(22):7024-34. Epub 2011 Nov 8.

Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California 94158, USA.

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November 2011

Gene expression and biological pathways in tissue of men with prostate cancer in a randomized clinical trial of lycopene and fish oil supplementation.

Authors:

Mark Jesus M Magbanua Ritu Roy Eduardo V Sosa Vivian Weinberg Scott Federman Michael D Mattie Millie Hughes-Fulford Jeff Simko Katsuto Shinohara Christopher M Haqq Peter R Carroll June M Chan

PLoS One 2011 1;6(9):e24004. Epub 2011 Sep 1.

Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California, United States of America.

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December 2011

Genomic alterations and phenotype of large compared to small high-grade ductal carcinoma in situ.

Authors:

E Shelley Hwang Aseem Lal Yunn-Yi Chen Sandy DeVries Rebecca Swain Joe Anderson Ritu Roy Frederic M Waldman

Hum Pathol 2011 Oct 14;42(10):1467-75. Epub 2011 Apr 14.

Department of Surgery, University of California San Francisco, San Francisco, CA 94143-1710, USA.

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October 2011

Mutations in GNA11 in uveal melanoma.

N Engl J Med 2010 Dec 17;363(23):2191-9. Epub 2010 Nov 17.

Department of Medical Genetics, University of British Columbia, Vancouver, Canada.

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December 2010

Germline variation controls the architecture of somatic alterations in tumors.

Authors:

Amy M Dworkin Katie Ridd Dianne Bautista Dawn C Allain O Hans Iwenofu Ritu Roy Boris C Bastian Amanda Ewart Toland

PLoS Genet 2010 Sep 23;6(9):e1001136. Epub 2010 Sep 23.

Integrated Biomedical Sciences Graduate Program, The Ohio State University, Columbus, Ohio, United States of America.

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September 2010

Genetic and morphologic features for melanoma classification.

Authors:

Sigrid M C Broekaert Ritu Roy Ichiro Okamoto Joost van den Oord Jürgen Bauer Claus Garbe Raymond L Barnhill Klaus J Busam Alistair J Cochran Martin G Cook David E Elder Stanley W McCarthy Martin C Mihm Dirk Schadendorf Richard A Scolyer Alan Spatz Boris C Bastian

Pigment Cell Melanoma Res 2010 Dec;23(6):763-70

Department of Dermatology, University of California San Francisco, 1701 Divisadero St, San Francisco, CA 94115, USA.

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December 2010

A group of genome-based biomarkers that add to a Kattan nomogram for predicting progression in men with high-risk prostate cancer.

Authors:

Pamela L Paris Vivian Weinberg Giancarlo Albo Ritu Roy Catherine Burke Jeffry Simko Peter Carroll Colin Collins

Clin Cancer Res 2010 Jan 22;16(1):195-202. Epub 2009 Dec 22.

Department of Urology, Helen Diller Family Comprehensive Cancer, and Helen Diller Family Comprehensive Cancer Biostatistics Core, University of California at San Francisco, California 94143, USA.

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January 2010