Publications Authored by Rita T Lawlor

The 2019 ISBER Americas Regional Meeting: Times They Are A Changin'-Biobanks for the Future.

Authors:

William Schleif Rita T Lawlor Allison Hubel Zisis Kozlakidis Marianne K Henderson

Biopreserv Biobank 2019 Oct 17;17(5):483-484. Epub 2019 Sep 17.

National Cancer Institute, NIH, DHHS, Bethesda, Maryland.

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http://dx.doi.org/10.1089/bio.2019.29058.wjs	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6913788	PMC

October 2019

Competitive Testing of the WHO 2010 versus the WHO 2017 Grading of Pancreatic Neuroendocrine Neoplasms: Data from a Large International Cohort Study.

Neuroendocrinology 2018 9;107(4):375-386. Epub 2018 Oct 9.

Pancreatic Surgery Unit, San Raffaele Scientific Institute, Milan, Italy.

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http://dx.doi.org/10.1159/000494355	DOI Listing

September 2019

Gene Expression Profiling of Lung Atypical Carcinoids and Large Cell Neuroendocrine Carcinomas Identifies Three Transcriptomic Subtypes with Specific Genomic Alterations.

J Thorac Oncol 2019 Sep 11;14(9):1651-1661. Epub 2019 May 11.

Comprehensive Cancer Center, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy; Sacred Hearth Catholic University, Rome, Italy.

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http://dx.doi.org/10.1016/j.jtho.2019.05.003	DOI Listing

September 2019

The Italian Rare Pancreatic Exocrine Cancer Initiative.

Tumori 2019 Aug 9;105(4):353-358. Epub 2019 Apr 9.

1 Medical Oncology Unit, IRCCS Cancer Institute "Giovanni Paolo II" of Bari, Bari, Italy.

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http://dx.doi.org/10.1177/0300891619839461	DOI Listing

August 2019

Genetic variability of the ABCC2 gene and clinical outcomes in pancreatic cancer patients.

Carcinogenesis 2019 Jun;40(4):544-550

Department of Biology, University of Pisa, Pisa, Italy.

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https://academic.oup.com/carcin/advance-article/doi/10.1093/	Publisher Site
http://dx.doi.org/10.1093/carcin/bgz006	DOI Listing

June 2019

Pancreatic cancer arising in the remnant pancreas is not always a relapse of the preceding primary.

Authors:

Claudio Luchini Antonio Pea Jun Yu Jin He Roberto Salvia Giulio Riva Matthew J Weiss Claudio Bassi John L Cameron Ralph H Hruban Michael Goggins Christopher L Wolfgang Aldo Scarpa Laura D Wood Rita T Lawlor

Mod Pathol 2019 05 22;32(5):659-665. Epub 2018 Nov 22.

ARC-Net Research Center, University of Verona, Verona, Italy.

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http://dx.doi.org/10.1038/s41379-018-0183-7	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760648	PMC

May 2019

Telomere length and health outcomes: An umbrella review of systematic reviews and meta-analyses of observational studies.

Authors:

Lee Smith Claudio Luchini Jacopo Demurtas Pinar Soysal Brendon Stubbs Mark Hamer Alessia Nottegar Rita T Lawlor Guillermo Felipe Lopez-Sanchez Joseph Firth Ai Koyanagi Justin Roberts Peter Willeit Thomas Waldhoer Mike Loosemore Adam David Abbs James Johnstone Lin Yang Nicola Veronese

Ageing Res Rev 2019 05 15;51:1-10. Epub 2019 Feb 15.

National Research Council, Neuroscience Institute, Aging Branch, Padova, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.arr.2019.02.003	DOI Listing

May 2019

Cyst Fluid Biosignature to Predict Intraductal Papillary Mucinous Neoplasms of the Pancreas with High Malignant Potential.

Authors:

Ajay V Maker Vincent Hu Shrihari S Kadkol Lenny Hong William Brugge Jordan Winter Charles J Yeo Thilo Hackert Markus Büchler Rita T Lawlor Roberto Salvia Aldo Scarpa Claudio Bassi Stefan Green

J Am Coll Surg 2019 May 19;228(5):721-729. Epub 2019 Feb 19.

Department of DNA Services, University of Illinois at Chicago, Chicago, IL.

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http://dx.doi.org/10.1016/j.jamcollsurg.2019.02.040	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487216	PMC

May 2019

Analytical Validation of Multiplex Biomarker Assay to Stratify Colorectal Cancer into Molecular Subtypes.

Sci Rep 2019 May 21;9(1):7665. Epub 2019 May 21.

Division of Molecular Pathology, The Institute of Cancer Research, London, United Kingdom.

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http://dx.doi.org/10.1038/s41598-019-43492-0	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529539	PMC

May 2019

Pancreatic cancer and autoimmune diseases: An association sustained by computational and epidemiological case-control approaches.

Int J Cancer 2019 04 26;144(7):1540-1549. Epub 2018 Oct 26.

PanGenEU Study Investigators (Additional file 1: Annex S1).

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http://dx.doi.org/10.1002/ijc.31866	DOI Listing

April 2019

Placenta-Specific 8 Is Overexpressed and Regulates Cell Proliferation in Low-Grade Human Pancreatic Neuroendocrine Tumors.

Authors:

Marina Tatura Harald Schmidt Mikail Haijat Maren Stark Anja Rinke Ramona Diels Rita T Lawlor Aldo Scarpa Joerg Schrader Thilo Hackert Simon Schimmack Thomas Matthias Gress Malte Buchholz

Neuroendocrinology 2020 25;110(1-2):23-34. Epub 2019 Apr 25.

Department of Medicine, Division of Gastroenterology, Endocrinology and Metabolism, Philipps University Marburg, Marburg, Germany,

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http://dx.doi.org/10.1159/000500541	DOI Listing

April 2019

Genetic determinants of telomere length and risk of pancreatic cancer: A PANDoRA study.

Authors:

Daniele Campa Martina Matarazzi William Greenhalf Maarten Bijlsma Kai-Uwe Saum Claudio Pasquali Hanneke van Laarhoven Andrea Szentesi Francesca Federici Pavel Vodicka Niccola Funel Raffaele Pezzilli H Bas Bueno-de-Mesquita Ludmila Vodickova Daniela Basso Ofure Obazee Thilo Hackert Pavel Soucek Katarina Cuk Jörg Kaiser Cosimo Sperti Martin Lovecek Gabriele Capurso Beatrice Mohelnikova-Duchonova Kay-Tee Khaw Anna-Katharina König Juozas Kupcinskas Rudolf Kaaks Franco Bambi Livia Archibugi Andrea Mambrini Giulia Martina Cavestro Stefano Landi Péter Hegyi Jakob R Izbicki Domenica Gioffreda Carlo Federico Zambon Francesca Tavano Renata Talar-Wojnarowska Krzysztof Jamroziak Timothy J Key Gianfranco Delle Fave Oliver Strobel Laimas Jonaitis Angelo Andriulli Rita T Lawlor Felice Pirozzi Verena Katzke Chiara Valsuani Yogesh K Vashist Hermann Brenner Federico Canzian

Int J Cancer 2019 03 12;144(6):1275-1283. Epub 2018 Nov 12.

Genomic Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://doi.wiley.com/10.1002/ijc.31928	Publisher Site
http://dx.doi.org/10.1002/ijc.31928	DOI Listing

March 2019

Alternative lengthening of telomeres (ALT) influences survival in soft tissue sarcomas: a systematic review with meta-analysis.

Authors:

Rita T Lawlor Nicola Veronese Antonio Pea Alessia Nottegar Lee Smith Camilla Pilati Jacopo Demurtas Matteo Fassan Liang Cheng Claudio Luchini

BMC Cancer 2019 Mar 14;19(1):232. Epub 2019 Mar 14.

Department of Diagnostics and Public Health, Section of Pathology, University and Hospital Trust of Verona, Piazzale Scuro, 10, 37134, Verona, Italy.

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http://dx.doi.org/10.1186/s12885-019-5424-8	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419345	PMC

March 2019

CD200 expression is a feature of solid pseudopapillary neoplasms of the pancreas.

Authors:

Rita T Lawlor Valentina Daprà Ilaria Girolami Antonio Pea Camilla Pilati Alessia Nottegar Paola Piccoli Claudia Parolini Nicola Sperandio Paola Capelli Aldo Scarpa Claudio Luchini

Virchows Arch 2019 Jan 21;474(1):105-109. Epub 2018 Aug 21.

Department of Diagnostics and Public Health, Section of Pathology, University and Hospital Trust of Verona, Piazzale Scuro, 10, 37134, Verona, Italy.

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http://dx.doi.org/10.1007/s00428-018-2437-7	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323071	PMC

January 2019

Molecular alterations associated with metastases of solid pseudopapillary neoplasms of the pancreas.

J Pathol 2019 01 27;247(1):123-134. Epub 2018 Nov 27.

ARC-Net Research Centre, University and Hospital Trust of Verona, Verona, Italy.

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http://dx.doi.org/10.1002/path.5180	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588017	PMC

January 2019

Perineural Invasion is a Strong Prognostic Moderator in Ampulla of Vater Carcinoma: A Meta-analysis.

Authors:

Claudio Luchini Nicola Veronese Alessia Nottegar Giulio Riva Camilla Pilati Andrea Mafficini Brendon Stubbs Michele Simbolo Aldo Mombello Vincenzo Corbo Liang Cheng Shinichi Yachida Laura D Wood Rita T Lawlor Roberto Salvia Aldo Scarpa

Pancreas 2019 01;48(1):70-76

Department of General and Pancreatic Surgery, The Pancreas Institute, University and Hospital Trust of Verona, Verona, Italy.

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http://Insights.ovid.com/crossref?an=00006676-900000000-9850	Publisher Site
http://dx.doi.org/10.1097/MPA.0000000000001194	DOI Listing

January 2019

Prognostic Role of High-Grade Tumor Budding in Pancreatic Ductal Adenocarcinoma: A Systematic Review and Meta-Analysis with a Focus on Epithelial to Mesenchymal Transition.

Authors:

Rita T Lawlor Nicola Veronese Alessia Nottegar Giuseppe Malleo Lee Smith Jacopo Demurtas Liang Cheng Laura D Wood Nicola Silvestris Roberto Salvia Aldo Scarpa Claudio Luchini

Cancers (Basel) 2019 Jan 19;11(1). Epub 2019 Jan 19.

Department of Diagnostics and Public Health, Section of Pathology, University of Verona, 37134 Verona, Italy.

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http://dx.doi.org/10.3390/cancers11010113	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356259	PMC

January 2019

Mutational and copy number asset of primary sporadic neuroendocrine tumors of the small intestine.

Authors:

Michele Simbolo Caterina Vicentini Andrea Mafficini Matteo Fassan Serena Pedron Vincenzo Corbo Luca Mastracci Borislav Rusev Corrado Pedrazzani Luca Landoni Federica Grillo Sara Cingarlini Guido Rindi Claudio Luchini Aldo Scarpa Rita T Lawlor

Virchows Arch 2018 Dec 16;473(6):709-717. Epub 2018 Sep 16.

ARC-Net Research Centre, University and Hospital Trust of Verona, Policlinico GB Rossi, Piazzale L.A. Scuro, 10, Piastra Odontoiatrica (II floor), Verona, Italy.

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http://dx.doi.org/10.1007/s00428-018-2450-x	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267237	PMC

December 2018

Induction of immunosuppressive functions and NF-κB by FLIP in monocytes.

Nat Commun 2018 12 5;9(1):5193. Epub 2018 Dec 5.

Department of Medicine, Section of Immunology, University of Verona, Verona, 37134, Italy.

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http://www.nature.com/articles/s41467-018-07654-4	Publisher Site
http://dx.doi.org/10.1038/s41467-018-07654-4	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281604	PMC

December 2018

PD-1, PD-L1, and CD163 in pancreatic undifferentiated carcinoma with osteoclast-like giant cells: expression patterns and clinical implications.

Hum Pathol 2018 11 18;81:157-165. Epub 2018 Jul 18.

Department of Diagnostics and Public Health, Section of Pathology, University of Verona, 37134 Verona, Italy; ARC-Net Research Center, University of Verona, 37134 Verona, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2018.07.006	DOI Listing

November 2018

Whole-exome sequencing of duodenal neuroendocrine tumors in patients with neurofibromatosis type 1.

Authors:

Michaël Noë Antonio Pea Claudio Luchini Matthäus Felsenstein Stefano Barbi Feriyl Bhaijee Raluca Yonescu Yi Ning N Volkan Adsay Giuseppe Zamboni Rita T Lawlor Aldo Scarpa G Johan A Offerhaus Lodewijk A A Brosens Ralph H Hruban Nicholas J Roberts Laura D Wood

Mod Pathol 2018 10 30;31(10):1532-1538. Epub 2018 May 30.

Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1038/s41379-018-0082-y	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168403	PMC

October 2018

Comparison Between Prognostic Classifications in De Novo Metastatic Hormone Sensitive Prostate Cancer.

Authors:

Roberto Iacovelli Chiara Ciccarese Claudia Mosillo Davide Bimbatti Emanuela Fantinel Lisa Stefani Michele Simbolo Mario Romano Renzo Mazzarotto Matteo Brunelli Emilio Bria Aldo Scarpa Rita T Lawlor Walter Artibani Giampaolo Tortora

Target Oncol 2018 10;13(5):649-655

Medical Oncology Unit, Azienda Ospedaliera Universitaria Integrata di Verona, Piazzale L.A. Scuro 10, 37134, Verona, Italy.

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http://dx.doi.org/10.1007/s11523-018-0588-8	DOI Listing

October 2018

ERG alterations and mTOR pathway activation in primary prostate carcinomas developing castration-resistance.

Authors:

Caterina Vicentini Cinzia Cantù Davide Antonello Michele Simbolo Andrea Mafficini Claudio Luchini Borislav Rusev Antonio Benito Porcaro Roberto Iacovelli Matteo Fassan Vincenzo Corbo Matteo Brunelli Walter Artibani Aldo Scarpa Rita T Lawlor

Pathol Res Pract 2018 Oct 29;214(10):1675-1680. Epub 2018 Aug 29.

ARC-NET Research Centre, University of Verona, Verona, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S03440338183079	Publisher Site
http://dx.doi.org/10.1016/j.prp.2018.08.031	DOI Listing

October 2018

Genetic Analysis of Small Well-differentiated Pancreatic Neuroendocrine Tumors Identifies Subgroups With Differing Risks of Liver Metastases.

Ann Surg 2018 Oct 17. Epub 2018 Oct 17.

Department of Surgery, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University School of Medicine, Baltimore, MD.

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http://Insights.ovid.com/crossref?an=00000658-900000000-9535	Publisher Site
http://dx.doi.org/10.1097/SLA.0000000000003022	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565500	PMC

October 2018

Common genetic variants associated with pancreatic adenocarcinoma may also modify risk of pancreatic neuroendocrine neoplasms.

Carcinogenesis 2018 07;39(7):969

Department of Biology, University of Pisa, Pisa, Italy.

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http://dx.doi.org/10.1093/carcin/bgy067	DOI Listing

July 2018

Genomic characterization of biliary tract cancers identifies driver genes and predisposing mutations.

J Hepatol 2018 05 31;68(5):959-969. Epub 2018 Jan 31.

Laboratory for Genome Sequencing Analysis, RIKEN Center for Integrative Medical Sciences, Tokyo 108-8639, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2018.01.009	DOI Listing

May 2018

Genetic alterations analysis in prognostic stratified groups identified TP53 and ARID1A as poor clinical performance markers in intrahepatic cholangiocarcinoma.

Authors:

Michele Simbolo Caterina Vicentini Andrea Ruzzenente Matteo Brunelli Simone Conci Matteo Fassan Andrea Mafficini Borislav Rusev Vincenzo Corbo Paola Capelli Emilio Bria Serena Pedron Giona Turri Rita T Lawlor Giampaolo Tortora Claudio Bassi Alfredo Guglielmi Aldo Scarpa

Sci Rep 2018 05 8;8(1):7119. Epub 2018 May 8.

ARC-Net Research Centre, University and Hospital Trust of Verona, Verona, Italy.

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http://dx.doi.org/10.1038/s41598-018-25669-1	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940669	PMC

May 2018

Common genetic variants associated with pancreatic adenocarcinoma may also modify risk of pancreatic neuroendocrine neoplasms.

Carcinogenesis 2018 03;39(3):360-367

Department of Biology, University of Pisa, Pisa, Italy.

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http://dx.doi.org/10.1093/carcin/bgx150	DOI Listing

March 2018

Biospecimens and Biobanking in Global Health.

Authors:

Maimuna Mendy Rita T Lawlor Anne Linda van Kappel Peter H J Riegman Fay Betsou Oliver D Cohen Marianne K Henderson

Clin Lab Med 2018 03 24;38(1):183-207. Epub 2017 Dec 24.

Center for Global Health, National Cancer Institute, NIH, DHHS, 9609 Medical Center Drive, Room 3W534, Bethesda, MD 20892, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cll.2017.10.015	DOI Listing

March 2018

Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer.

Authors:

Alison P Klein Brian M Wolpin Harvey A Risch Rachael Z Stolzenberg-Solomon Evelina Mocci Mingfeng Zhang Federico Canzian Erica J Childs Jason W Hoskins Ashley Jermusyk Jun Zhong Fei Chen Demetrius Albanes Gabriella Andreotti Alan A Arslan Ana Babic William R Bamlet Laura Beane-Freeman Sonja I Berndt Amanda Blackford Michael Borges Ayelet Borgida Paige M Bracci Lauren Brais Paul Brennan Hermann Brenner Bas Bueno-de-Mesquita Julie Buring Daniele Campa Gabriele Capurso Giulia Martina Cavestro Kari G Chaffee Charles C Chung Sean Cleary Michelle Cotterchio Frederike Dijk Eric J Duell Lenka Foretova Charles Fuchs Niccola Funel Steven Gallinger J Michael M Gaziano Maria Gazouli Graham G Giles Edward Giovannucci Michael Goggins Gary E Goodman Phyllis J Goodman Thilo Hackert Christopher Haiman Patricia Hartge Manal Hasan Peter Hegyi Kathy J Helzlsouer Joseph Herman Ivana Holcatova Elizabeth A Holly Robert Hoover Rayjean J Hung Eric J Jacobs Krzysztof Jamroziak Vladimir Janout Rudolf Kaaks Kay-Tee Khaw Eric A Klein Manolis Kogevinas Charles Kooperberg Matthew H Kulke Juozas Kupcinskas Robert J Kurtz Daniel Laheru Stefano Landi Rita T Lawlor I-Min Lee Loic LeMarchand Lingeng Lu Núria Malats Andrea Mambrini Satu Mannisto Roger L Milne Beatrice Mohelníková-Duchoňová Rachel E Neale John P Neoptolemos Ann L Oberg Sara H Olson Irene Orlow Claudio Pasquali Alpa V Patel Ulrike Peters Raffaele Pezzilli Miquel Porta Francisco X Real Nathaniel Rothman Ghislaine Scelo Howard D Sesso Gianluca Severi Xiao-Ou Shu Debra Silverman Jill P Smith Pavel Soucek Malin Sund Renata Talar-Wojnarowska Francesca Tavano Mark D Thornquist Geoffrey S Tobias Stephen K Van Den Eeden Yogesh Vashist Kala Visvanathan Pavel Vodicka Jean Wactawski-Wende Zhaoming Wang Nicolas Wentzensen Emily White Herbert Yu Kai Yu Anne Zeleniuch-Jacquotte Wei Zheng Peter Kraft Donghui Li Stephen Chanock Ofure Obazee Gloria M Petersen Laufey T Amundadottir

Nat Commun 2018 02 8;9(1):556. Epub 2018 Feb 8.

Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1038/s41467-018-02942-5	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805680	PMC

February 2018

Ampulla of Vater Carcinoma: Sequencing Analysis Identifies TP53 Status as a Novel Independent Prognostic Factor and Potentially Actionable ERBB, PI3K, and WNT Pathways Gene Mutations.

Authors:

Andrea Mafficini Eliana Amato Ivana Cataldo Borislav C Rusev Luca Bertoncello Vincenzo Corbo Michele Simbolo Claudio Luchini Matteo Fassan Cinzia Cantù Roberto Salvia Giovanni Marchegiani Giampaolo Tortora Rita T Lawlor Claudio Bassi Aldo Scarpa

Ann Surg 2018 Jan;267(1):149-156

ARC-NET Research Centre, University of Verona, Verona, Italy.

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http://Insights.ovid.com/crossref?an=00000658-201801000-0002	Publisher Site
http://dx.doi.org/10.1097/SLA.0000000000001999	DOI Listing

January 2018

Combined microRNA and mRNA microfluidic TaqMan array cards for the diagnosis of malignancy of multiple types of pancreatico-biliary tumors in fine-needle aspiration material.

Authors:

Thomas M Gress Ludwig Lausser Lyn-Rouven Schirra Lisa Ortmüller Ramona Diels Bo Kong Christoph W Michalski Thilo Hackert Oliver Strobel Nathalia A Giese Miriam Schenk Rita T Lawlor Aldo Scarpa Hans A Kestler Malte Buchholz

Oncotarget 2017 Dec 21;8(64):108223-108237. Epub 2017 Nov 21.

Clinic for Gastroenterology, Endocrinology and Metabolism, University Hospital, Philipps-Universität Marburg, Marburg, Germany.

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http://www.oncotarget.com/fulltext/22601	Publisher Site
http://dx.doi.org/10.18632/oncotarget.22601	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746138	PMC

December 2017

Corrigendum: Whole-genome landscape of pancreatic neuroendocrine tumours.

Authors:

Aldo Scarpa David K Chang Katia Nones Vincenzo Corbo Ann-Marie Patch Peter Bailey Rita T Lawlor Amber L Johns David K Miller Andrea Mafficini Borislav Rusev Maria Scardoni Davide Antonello Stefano Barbi Katarzyna O Sikora Sara Cingarlini Caterina Vicentini Skye McKay Michael C J Quinn Timothy J C Bruxner Angelika N Christ Ivon Harliwong Senel Idrisoglu Suzanne McLean Craig Nourse Ehsan Nourbakhsh Peter J Wilson Matthew J Anderson J Lynn Fink Felicity Newell Nick Waddell Oliver Holmes Stephen H Kazakoff Conrad Leonard Scott Wood Qinying Xu Shivashankar Hiriyur Nagaraj Eliana Amato Irene Dalai Samantha Bersani Ivana Cataldo Angelo P Dei Tos Paola Capelli Maria Vittoria Davì Luca Landoni Anna Malpaga Marco Miotto Vicki L J Whitehall Barbara A Leggett Janelle L Harris Jonathan Harris Marc D Jones Jeremy Humphris Lorraine A Chantrill Venessa Chin Adnan M Nagrial Marina Pajic Christopher J Scarlett Andreia Pinho Ilse Rooman Christopher Toon Jianmin Wu Mark Pinese Mark Cowley Andrew Barbour Amanda Mawson Emily S Humphrey Emily K Colvin Angela Chou Jessica A Lovell Nigel B Jamieson Fraser Duthie Marie-Claude Gingras William E Fisher Rebecca A Dagg Loretta M S Lau Michael Lee Hilda A Pickett Roger R Reddel Jaswinder S Samra James G Kench Neil D Merrett Krishna Epari Nam Q Nguyen Nikolajs Zeps Massimo Falconi Michele Simbolo Giovanni Butturini George Van Buren Stefano Partelli Matteo Fassan Kum Kum Khanna Anthony J Gill David A Wheeler Richard A Gibbs Elizabeth A Musgrove Claudio Bassi Giampaolo Tortora Paolo Pederzoli John V Pearson Nicola Waddell Andrew V Biankin Sean M Grimmond

Nature 2017 10 27;550(7677):548. Epub 2017 Sep 27.

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http://dx.doi.org/10.1038/nature24026	DOI Listing

October 2017

Lack of Association for Reported Endocrine Pancreatic Cancer Risk Loci in the PANDoRA Consortium.

Cancer Epidemiol Biomarkers Prev 2017 08;26(8):1349-1351

Genomic Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1158/1055-9965.EPI-17-0075	DOI Listing

August 2017

Splice variants as novel targets in pancreatic ductal adenocarcinoma.

Authors:

Jun Wang Laurent Dumartin Andrea Mafficini Pinar Ulug Ajanthah Sangaralingam Namaa Audi Alamiry Tomasz P Radon Roberto Salvia Rita T Lawlor Nicholas R Lemoine Aldo Scarpa Claude Chelala Tatjana Crnogorac-Jurcevic

Sci Rep 2017 06 7;7(1):2980. Epub 2017 Jun 7.

Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, John Vane Science Centre, London, EC1M 6BQ, UK.

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http://dx.doi.org/10.1038/s41598-017-03354-z	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462735	PMC

June 2017

Lung neuroendocrine tumours: deep sequencing of the four World Health Organization histotypes reveals chromatin-remodelling genes as major players and a prognostic role for TERT, RB1, MEN1 and KMT2D.

J Pathol 2017 03 29;241(4):488-500. Epub 2016 Dec 29.

ARC-Net Research Centre, University and Hospital Trust of Verona, Verona, Italy.

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http://dx.doi.org/10.1002/path.4853	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324596	PMC

March 2017

Whole-genome landscape of pancreatic neuroendocrine tumours.

Authors:

Aldo Scarpa David K Chang Katia Nones Vincenzo Corbo Ann-Marie Patch Peter Bailey Rita T Lawlor Amber L Johns David K Miller Andrea Mafficini Borislav Rusev Maria Scardoni Davide Antonello Stefano Barbi Katarzyna O Sikora Sara Cingarlini Caterina Vicentini Skye McKay Michael C J Quinn Timothy J C Bruxner Angelika N Christ Ivon Harliwong Senel Idrisoglu Suzanne McLean Craig Nourse Ehsan Nourbakhsh Peter J Wilson Matthew J Anderson J Lynn Fink Felicity Newell Nick Waddell Oliver Holmes Stephen H Kazakoff Conrad Leonard Scott Wood Qinying Xu Shivashankar Hiriyur Nagaraj Eliana Amato Irene Dalai Samantha Bersani Ivana Cataldo Angelo P Dei Tos Paola Capelli Maria Vittoria Davì Luca Landoni Anna Malpaga Marco Miotto Vicki L J Whitehall Barbara A Leggett Janelle L Harris Jonathan Harris Marc D Jones Jeremy Humphris Lorraine A Chantrill Venessa Chin Adnan M Nagrial Marina Pajic Christopher J Scarlett Andreia Pinho Ilse Rooman Christopher Toon Jianmin Wu Mark Pinese Mark Cowley Andrew Barbour Amanda Mawson Emily S Humphrey Emily K Colvin Angela Chou Jessica A Lovell Nigel B Jamieson Fraser Duthie Marie-Claude Gingras William E Fisher Rebecca A Dagg Loretta M S Lau Michael Lee Hilda A Pickett Roger R Reddel Jaswinder S Samra James G Kench Neil D Merrett Krishna Epari Nam Q Nguyen Nikolajs Zeps Massimo Falconi Michele Simbolo Giovanni Butturini George Van Buren Stefano Partelli Matteo Fassan Kum Kum Khanna Anthony J Gill David A Wheeler Richard A Gibbs Elizabeth A Musgrove Claudio Bassi Giampaolo Tortora Paolo Pederzoli John V Pearson Nicola Waddell Andrew V Biankin Sean M Grimmond

Nature 2017 03 15;543(7643):65-71. Epub 2017 Feb 15.

University of Melbourne Centre for Cancer Research, University of Melbourne, Melbourne, 3010, Victoria, Australia.

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http://dx.doi.org/10.1038/nature21063	DOI Listing

March 2017

Hypermutation In Pancreatic Cancer.

Authors:

Jeremy L Humphris Ann-Marie Patch Katia Nones Peter J Bailey Amber L Johns Skye McKay David K Chang David K Miller Marina Pajic Karin S Kassahn Michael C J Quinn Timothy J C Bruxner Angelika N Christ Ivon Harliwong Senel Idrisoglu Suzanne Manning Craig Nourse Ehsan Nourbakhsh Andrew Stone Peter J Wilson Matthew Anderson J Lynn Fink Oliver Holmes Stephen Kazakoff Conrad Leonard Felicity Newell Nick Waddell Scott Wood Ronald S Mead Qinying Xu Jianmin Wu Mark Pinese Mark J Cowley Marc D Jones Adnan M Nagrial Venessa T Chin Lorraine A Chantrill Amanda Mawson Angela Chou Christopher J Scarlett Andreia V Pinho Ilse Rooman Marc Giry-Laterriere Jaswinder S Samra James G Kench Neil D Merrett Christopher W Toon Krishna Epari Nam Q Nguyen Andrew Barbour Nikolajs Zeps Nigel B Jamieson Colin J McKay C Ross Carter Euan J Dickson Janet S Graham Fraser Duthie Karin Oien Jane Hair Jennifer P Morton Owen J Sansom Robert Grützmann Ralph H Hruban Anirban Maitra Christine A Iacobuzio-Donahue Richard D Schulick Christopher L Wolfgang Richard A Morgan Rita T Lawlor Borislav Rusev Vincenzo Corbo Roberto Salvia Ivana Cataldo Giampaolo Tortora Margaret A Tempero Oliver Hofmann James R Eshleman Christian Pilarsky Aldo Scarpa Elizabeth A Musgrove Anthony J Gill John V Pearson Sean M Grimmond Nicola Waddell Andrew V Biankin

Gastroenterology 2017 01 15;152(1):68-74.e2. Epub 2016 Nov 15.

Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom; Department of Surgery, Bankstown Hospital, Bankstown, Sydney, New South Wales, Australia; South Western Sydney Clinical School, Faculty of Medicine, University of New South Wales Australia, Liverpool, New South Wales, Australia; West of Scotland Pancreatic Unit, Glasgow Royal Infirmary, Glasgow, United Kingdom. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00165085163518	Publisher Site
http://dx.doi.org/10.1053/j.gastro.2016.09.060	DOI Listing

January 2017

Common germline variants within the CDKN2A/2B region affect risk of pancreatic neuroendocrine tumors.

Sci Rep 2016 12 23;6:39565. Epub 2016 Dec 23.

Genomic Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/srep39565	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5180167	PMC

December 2016

The pattern of hMENA isoforms is regulated by TGF-β1 in pancreatic cancer and may predict patient outcome.

Authors:

Roberta Melchionna Pierluigi Iapicca Francesca Di Modugno Paola Trono Isabella Sperduti Matteo Fassan Ivana Cataldo Borislav C Rusev Rita T Lawlor Maria Grazia Diodoro Michele Milella Gian Luca Grazi Mina J Bissell Aldo Scarpa Paola Nisticò

Oncoimmunology 2016 12;5(12):e1221556. Epub 2016 Aug 12.

Tumour Immunology and Immunotherapy Unit, Regina Elena National Cancer Institute , Rome, Italy.

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http://dx.doi.org/10.1080/2162402X.2016.1221556	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5213039	PMC

August 2016

Cholangiocarcinoma Heterogeneity Revealed by Multigene Mutational Profiling: Clinical and Prognostic Relevance in Surgically Resected Patients.

Authors:

Andrea Ruzzenente Matteo Fassan Simone Conci Michele Simbolo Rita T Lawlor Corrado Pedrazzani Paola Capelli Mirko D'Onofrio Calogero Iacono Aldo Scarpa Alfredo Guglielmi

Ann Surg Oncol 2016 May 30;23(5):1699-707. Epub 2015 Dec 30.

Department of Surgery, General and Hepatobiliary Surgery, University Hospital G.B. Rossi, University of Verona, Verona, Italy.

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http://dx.doi.org/10.1245/s10434-015-5046-6	DOI Listing

May 2016

Genomic analyses identify molecular subtypes of pancreatic cancer.

Authors:

Peter Bailey David K Chang Katia Nones Amber L Johns Ann-Marie Patch Marie-Claude Gingras David K Miller Angelika N Christ Tim J C Bruxner Michael C Quinn Craig Nourse L Charles Murtaugh Ivon Harliwong Senel Idrisoglu Suzanne Manning Ehsan Nourbakhsh Shivangi Wani Lynn Fink Oliver Holmes Venessa Chin Matthew J Anderson Stephen Kazakoff Conrad Leonard Felicity Newell Nick Waddell Scott Wood Qinying Xu Peter J Wilson Nicole Cloonan Karin S Kassahn Darrin Taylor Kelly Quek Alan Robertson Lorena Pantano Laura Mincarelli Luis N Sanchez Lisa Evers Jianmin Wu Mark Pinese Mark J Cowley Marc D Jones Emily K Colvin Adnan M Nagrial Emily S Humphrey Lorraine A Chantrill Amanda Mawson Jeremy Humphris Angela Chou Marina Pajic Christopher J Scarlett Andreia V Pinho Marc Giry-Laterriere Ilse Rooman Jaswinder S Samra James G Kench Jessica A Lovell Neil D Merrett Christopher W Toon Krishna Epari Nam Q Nguyen Andrew Barbour Nikolajs Zeps Kim Moran-Jones Nigel B Jamieson Janet S Graham Fraser Duthie Karin Oien Jane Hair Robert Grützmann Anirban Maitra Christine A Iacobuzio-Donahue Christopher L Wolfgang Richard A Morgan Rita T Lawlor Vincenzo Corbo Claudio Bassi Borislav Rusev Paola Capelli Roberto Salvia Giampaolo Tortora Debabrata Mukhopadhyay Gloria M Petersen Donna M Munzy William E Fisher Saadia A Karim James R Eshleman Ralph H Hruban Christian Pilarsky Jennifer P Morton Owen J Sansom Aldo Scarpa Elizabeth A Musgrove Ulla-Maja Hagbo Bailey Oliver Hofmann Robert L Sutherland David A Wheeler Anthony J Gill Richard A Gibbs John V Pearson Nicola Waddell Andrew V Biankin Sean M Grimmond

Nature 2016 Mar 24;531(7592):47-52. Epub 2016 Feb 24.

Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia.

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http://dx.doi.org/10.1038/nature16965	DOI Listing

March 2016

"Life in Data"--Outcome of a Multi-Disciplinary, Interactive Biobanking Conference Session on Sample Data.

Authors:

Sara Y Nussbeck Muriel Rabone Erica E Benson Gabriele Droege Jackie Mackenzie-Dodds Rita T Lawlor

Biopreserv Biobank 2016 Feb 25;14(1):56-64. Epub 2016 Jan 25.

5 ARC-Net Applied Research on Cancer Centre, University of Verona , Verona, Italy .

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http://dx.doi.org/10.1089/bio.2015.0061	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761830	PMC

February 2016

New genomic landscapes and therapeutic targets for biliary tract cancers.

Authors:

Michele Simbolo Matteo Fassan Andrea Mafficini Rita T Lawlor Andrea Ruzzenente Aldo Scarpa

Front Biosci (Landmark Ed) 2016 Jan 1;21:707-18. Epub 2016 Jan 1.

ARC-Net Research Centre, University and Hospital Trust of Verona, Piazzale L. Scuro.

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http://dx.doi.org/10.2741/4416	DOI Listing

January 2016

BRCA somatic and germline mutation detection in paraffin embedded ovarian cancers by next-generation sequencing.

Authors:

Andrea Mafficini Michele Simbolo Alice Parisi Borislav Rusev Claudio Luchini Ivana Cataldo Elena Piazzola Nicola Sperandio Giona Turri Massimo Franchi Giampaolo Tortora Chiara Bovo Rita T Lawlor Aldo Scarpa

Oncotarget 2016 Jan;7(2):1076-83

ARC-Net Research Centre, University and Hospital Trust of Verona, Verona, Italy.

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http://dx.doi.org/10.18632/oncotarget.6834	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811444	PMC

January 2016

Loss of BAP1 Expression Occurs Frequently in Intrahepatic Cholangiocarcinoma.

Medicine (Baltimore) 2016 Jan;95(2):e2491

From the Cancer Diagnosis and Pathology Research Group, Kolling Institute of Medical Research, St Leonards, NSW, Australia (JA, LS, AC, MT, NW, MF, CWT, AJG); Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany (BG, MR, AS, WW, PS); Department of Anatomical Pathology, Royal North Shore Hospital, St Leonards (LS, AC, MF, AJG); Histopath Pathology, North Ryde (CWT); Sydney Medical School, University of Sydney, Sydney (JA,CWT, RCS, AM, JSS, TJH, AJG); Upper Gastrointestinal Surgical Unit, Royal North Shore Hospital, North Shore Private Hospital, St Leonards; Discipline of Surgery, University of Sydney (AM, JSS, TJH); Macquarie University Hospital, Macquarie University, Sydney (JSS); Department of Anatomical Pathology, SYDPATH, St Vincents Hospitals, Darlinghurst, NSW, Australia (AC); Department of Pathology and Diagnostics, ARC-NET Research Center (RTL, NS, AS); Department of Surgery, University and Hospital Trust of Verona, Verona, Italy (AR); and Sydney Vital Translational Research Centre, Royal North Shore Hospital, Pacific Highway, St Leonards, NSW, Australia (AJG).

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http://dx.doi.org/10.1097/MD.0000000000002491	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718285	PMC

January 2016

Reporting tumor molecular heterogeneity in histopathological diagnosis.

Authors:

Andrea Mafficini Eliana Amato Matteo Fassan Michele Simbolo Davide Antonello Caterina Vicentini Maria Scardoni Samantha Bersani Marisa Gottardi Borislav Rusev Giorgio Malpeli Vincenzo Corbo Stefano Barbi Katarzyna O Sikora Rita T Lawlor Giampaolo Tortora Aldo Scarpa

PLoS One 2014 15;9(8):e104979. Epub 2014 Aug 15.

Applied Research on Cancer Network (ARC-NET) and Department of Pathology and Diagnostics, University and Hospital Trust of Verona, Verona, Italy.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0104979	PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134249	PMC

December 2015

A Cross-Species Analysis in Pancreatic Neuroendocrine Tumors Reveals Molecular Subtypes with Distinctive Clinical, Metastatic, Developmental, and Metabolic Characteristics.

Authors:

Anguraj Sadanandam Stephan Wullschleger Costas A Lyssiotis Carsten Grötzinger Stefano Barbi Samantha Bersani Jan Körner Ismael Wafy Andrea Mafficini Rita T Lawlor Michele Simbolo John M Asara Hendrik Bläker Lewis C Cantley Bertram Wiedenmann Aldo Scarpa Douglas Hanahan

Cancer Discov 2015 Dec 7;5(12):1296-313. Epub 2015 Oct 7.

Swiss Institute for Experimental Cancer Research (ISREC), Swiss Federal Institute of Lausanne (EPFL), Lausanne, Switzerland.

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http://dx.doi.org/10.1158/2159-8290.CD-15-0068	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946251	PMC

December 2015

Evaluation of cell-free DNA as a biomarker for pancreatic malignancies.

Authors:

Katarzyna Sikora Chiara Bedin Caterina Vicentini Giorgio Malpeli Edoardo D'Angelo Nicola Sperandio Rita T Lawlor Claudio Bassi Giampaolo Tortora Donato Nitti Marco Agostini Matteo Fassan Aldo Scarpa

Int J Biol Markers 2015 Feb 24;30(1):e136-41. Epub 2015 Feb 24.

ARC-NET Research Centre, University of Verona, Verona - Italy.

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http://dx.doi.org/10.5301/jbm.5000088	DOI Listing

February 2015

Whole genomes redefine the mutational landscape of pancreatic cancer.

Authors:

Nicola Waddell Marina Pajic Ann-Marie Patch David K Chang Karin S Kassahn Peter Bailey Amber L Johns David Miller Katia Nones Kelly Quek Michael C J Quinn Alan J Robertson Muhammad Z H Fadlullah Tim J C Bruxner Angelika N Christ Ivon Harliwong Senel Idrisoglu Suzanne Manning Craig Nourse Ehsan Nourbakhsh Shivangi Wani Peter J Wilson Emma Markham Nicole Cloonan Matthew J Anderson J Lynn Fink Oliver Holmes Stephen H Kazakoff Conrad Leonard Felicity Newell Barsha Poudel Sarah Song Darrin Taylor Nick Waddell Scott Wood Qinying Xu Jianmin Wu Mark Pinese Mark J Cowley Hong C Lee Marc D Jones Adnan M Nagrial Jeremy Humphris Lorraine A Chantrill Venessa Chin Angela M Steinmann Amanda Mawson Emily S Humphrey Emily K Colvin Angela Chou Christopher J Scarlett Andreia V Pinho Marc Giry-Laterriere Ilse Rooman Jaswinder S Samra James G Kench Jessica A Pettitt Neil D Merrett Christopher Toon Krishna Epari Nam Q Nguyen Andrew Barbour Nikolajs Zeps Nigel B Jamieson Janet S Graham Simone P Niclou Rolf Bjerkvig Robert Grützmann Daniela Aust Ralph H Hruban Anirban Maitra Christine A Iacobuzio-Donahue Christopher L Wolfgang Richard A Morgan Rita T Lawlor Vincenzo Corbo Claudio Bassi Massimo Falconi Giuseppe Zamboni Giampaolo Tortora Margaret A Tempero Anthony J Gill James R Eshleman Christian Pilarsky Aldo Scarpa Elizabeth A Musgrove John V Pearson Andrew V Biankin Sean M Grimmond

Nature 2015 Feb;518(7540):495-501

1] Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia [2] Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Bearsden, Glasgow G61 1BD, UK.

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