Rita Shaknovich

Rita Shaknovich

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Rita Shaknovich

Rita Shaknovich

Publications by authors named "Rita Shaknovich"

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The new frontier of epigenetic heterogeneity in B-cell neoplasms.

Curr Opin Hematol 2017 Jul;24(4):402-408

aDivisions of Hematology and Medical Oncology, Department of Medicine bDepartments of Physiology and Biophysics, Institute for Computational Biomedicine, Weill Cornell Medicine cDepartment of Pathology, Mount Sinai School of Medicine, New York, New York, USA.

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http://dx.doi.org/10.1097/MOH.0000000000000348DOI Listing
July 2017

miR-181a negatively regulates NF-κB signaling and affects activated B-cell-like diffuse large B-cell lymphoma pathogenesis.

Blood 2016 06 3;127(23):2856-66. Epub 2016 Mar 3.

Division of Hematology and Oncology, Department of Medicine, Department of Molecular and Cellular Pharmacology.

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http://dx.doi.org/10.1182/blood-2015-11-680462DOI Listing
June 2016

DNA Methylation Dynamics of Germinal Center B Cells Are Mediated by AID.

Cell Rep 2015 Sep 10;12(12):2086-98. Epub 2015 Sep 10.

Division of Hematology and Oncology, Weill Cornell Medical College, New York, NY 10065, USA; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.08.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591215PMC
September 2015

TET1 is a tumor suppressor of hematopoietic malignancy.

Nat Immunol 2015 Jun 13;16(6):653-62. Epub 2015 Apr 13.

1] Howard Hughes Medical Institute and Department of Pathology, NYU School of Medicine, New York, New York, USA. [2] NYU Cancer Institute and Helen L. and Martin S. Kimmel Center for Stem Cell Biology, NYU School of Medicine, New York, New York, USA.

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http://dx.doi.org/10.1038/ni.3148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545281PMC
June 2015

Signatures of accelerated somatic evolution in gene promoters in multiple cancer types.

Nucleic Acids Res 2015 Jun 1;43(11):5307-17. Epub 2015 May 1.

Department of Medicine, University of Colorado School of Medicine, Aurora, CO, USA Computational Biosciences Program, University of Colorado-Denver, Aurora, CO, USA University of Colorado Cancer Center, Aurora, CO, USA Department of Biostatistics and Informatics, Colorado School of Public Health, Aurora, CO, USA

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http://dx.doi.org/10.1093/nar/gkv419DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477653PMC
June 2015

Epigenomic evolution in diffuse large B-cell lymphomas.

Nat Commun 2015 Apr 20;6:6921. Epub 2015 Apr 20.

1] Institute for Computational Biomedicine, Department of Physiology and Biophysics, Weill Cornell Medical College, 1300 York Avenue, New York, New York 10021, USA [2] Institute for Precision Medicine, Weill Cornell Medical College, 1300 York Avenue, New York, New York 10021, USA.

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http://dx.doi.org/10.1038/ncomms7921DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411286PMC
April 2015

Epigenetic function of activation-induced cytidine deaminase and its link to lymphomagenesis.

Front Immunol 2014 18;5:642. Epub 2014 Dec 18.

Division of Hematology and Oncology, Weill Cornell Medical College , New York, NY , USA ; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College , New York, NY , USA.

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http://dx.doi.org/10.3389/fimmu.2014.00642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270259PMC
January 2015

Epigenetic diversity in hematopoietic neoplasms.

Biochim Biophys Acta 2014 Dec 18;1846(2):477-84. Epub 2014 Sep 18.

Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Harvard School of Public Health, Boston, MA 02215, USA; Department of Biostatistics, Harvard School of Public Health, Boston, MA 02215, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbcan.2014.09.003DOI Listing
December 2014

GobyWeb: simplified management and analysis of gene expression and DNA methylation sequencing data.

PLoS One 2013 23;8(7):e69666. Epub 2013 Jul 23.

The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, The Weill Cornell Medical College, New York, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0069666PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720652PMC
March 2014

Gene expression and epigenetic deregulation.

Authors:
Rita Shaknovich

Adv Exp Med Biol 2013 ;792:133-50

Department of Medicine, Weill Cornell Medical College, 1300 York Avenue, New York, NY, 10021, USA,

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http://dx.doi.org/10.1007/978-1-4614-8051-8_6DOI Listing
February 2014

Down-regulation of eIF4GII by miR-520c-3p represses diffuse large B cell lymphoma development.

PLoS Genet 2014 Jan 30;10(1):e1004105. Epub 2014 Jan 30.

Marlene & Stewart Greenebaum Cancer Center, Department of Medicine, University of Maryland, Baltimore, Maryland, United States of America ; Veterans Administration Medical Center, Baltimore, Maryland, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1004105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907297PMC
January 2014

Mechanism-based epigenetic chemosensitization therapy of diffuse large B-cell lymphoma.

Cancer Discov 2013 Sep 16;3(9):1002-19. Epub 2013 Aug 16.

1Division of Hematology and Oncology, Department of Medicine, 2Division of Biostatistics and Epidemiology, Department of Public Health, 3Weill Cornell Cancer Center, and Departments of 4Pathology and 5Pharmacology, Weill Cornell Medical College, Cornell University, New York, New York; 6Section of Hematology/Oncology, Department of Medicine, The University of Chicago; Department of Pathology, Northwestern University, Chicago, Illinois; 8Institute for Research in Immunology and Cancer and Department of Pathology and Cell Biology, University of Montreal, Montreal, Quebec; 9Centre for Lymphoid Cancer, BC Cancer Agency, Vancouver, British Columbia, Canada; 10IBM Research, Rio de Janeiro, Brazil; and 11Department of Oncological Sciences, University of Turin, Turin, Italy.

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http://dx.doi.org/10.1158/2159-8290.CD-13-0117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770813PMC
September 2013

Mechanisms of epigenetic deregulation in lymphoid neoplasms.

Blood 2013 May;121(21):4271-9

Institute for Computational Biomedicine, Weill Cornell Medical College, New York, NY 10065, USA.

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http://dx.doi.org/10.1182/blood-2012-12-451799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663422PMC
May 2013

Incidence and clinical implications of ATM aberrations in chronic lymphocytic leukemia.

Genes Chromosomes Cancer 2012 Dec 6;51(12):1125-32. Epub 2012 Sep 6.

Department of Internal Medicine, Division of Hematology and Oncology, University of Michigan, Ann Arbor, MI 48109-0936,

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http://doi.wiley.com/10.1002/gcc.21997
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http://dx.doi.org/10.1002/gcc.21997DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465492PMC
December 2012

SYK inhibition and response prediction in diffuse large B-cell lymphoma.

Blood 2011 Dec 24;118(24):6342-52. Epub 2011 Oct 24.

Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY, USA.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2011-02-33
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http://dx.doi.org/10.1182/blood-2011-02-333773DOI Listing
December 2011

Epigenetics and B-cell lymphoma.

Curr Opin Hematol 2011 Jul;18(4):293-9

Department of Pathology, Weill Cornell Medical College, New York, New York 10065, USA.

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http://dx.doi.org/10.1097/MOH.0b013e32834788cfDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260081PMC
July 2011

BCL6 repression of EP300 in human diffuse large B cell lymphoma cells provides a basis for rational combinatorial therapy.

J Clin Invest 2010 Dec 1;120(12):4569-82. Epub 2010 Nov 1.

Hematology and Oncology Division, and Department of Pharmacology, Weill Cornell Medical College, New York, New York, USA. Department of Molecular Pharmacology and Chemistry, Sloan-Kettering Institute, New York, New York, USA. Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, British Columbia, Canada. Department of Pathology, Weill Cornell Medical College, New York, New York, USA. Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. The University of Kansas Cancer Center, Kansas University Medical Center, Kansas City, Kansas, USA. Centre for Lymphoid Cancers and the Departments of Pathology and Experimental Therapeutics, British Columbia Cancer Agency, British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1172/JCI42869DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993589PMC
December 2010

DNA methylation signatures define molecular subtypes of diffuse large B-cell lymphoma.

Blood 2010 Nov 7;116(20):e81-9. Epub 2010 Jul 7.

Division of Hematology/Oncology, Department of Medicine, Weill Cornell Medical College, New York, NY, USA.

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http://dx.doi.org/10.1182/blood-2010-05-285320DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993635PMC
November 2010

HELP (HpaII tiny fragment enrichment by ligation-mediated PCR) assay for DNA methylation profiling of primary normal and malignant B lymphocytes.

Methods Mol Biol 2010 ;632:191-201

Division of Immunopathology, Department of Pathology, Weill Medical College, Cornell University, New York, NY, USA.

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http://dx.doi.org/10.1007/978-1-60761-663-4_12DOI Listing
June 2010

A peptomimetic inhibitor of BCL6 with potent antilymphoma effects in vitro and in vivo.

Blood 2009 Apr 16;113(15):3397-405. Epub 2008 Oct 16.

Division of Hematology and Medical Oncology, Department of Medicine, Weill Cornell College of Medicine, New York, NY 10065, USA

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http://dx.doi.org/10.1182/blood-2008-07-168773DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2668844PMC
April 2009

Sequential transcription factor targeting for diffuse large B-cell lymphomas.

Cancer Res 2008 May;68(9):3361-9

Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-07-5817DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748725PMC
May 2008

Oncogenic viruses in AIDS: mechanisms of disease and intrathoracic manifestations.

AJR Am J Roentgenol 2007 Nov;189(5):1082-7

Department of Radiology, Albert Einstein College of Medicine and Montefiore Medical Center, 111 E 210th St., Bronx, NY 10467, USA.

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http://dx.doi.org/10.2214/AJR.07.2193DOI Listing
November 2007

Stages of germinal center transit are defined by B cell transcription factor coexpression and relative abundance.

J Immunol 2006 Nov;177(10):6930-9

Department of Pathology, Columbia University Medical Center, New York, NY 10032, USA.

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http://dx.doi.org/10.4049/jimmunol.177.10.6930DOI Listing
November 2006

Nuclear and cytoplasmic AID in extrafollicular and germinal center B cells.

Blood 2006 May 26;107(10):3967-75. Epub 2006 Jan 26.

Institute for Cancer Genetics, 1150 St Nicholas Avenue, Russ Berrie Science Pavilion, Rm 301, Columbia University, New York, NY 10032, USA.

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http://dx.doi.org/10.1182/blood-2005-10-4170DOI Listing
May 2006

PRDM1/Blimp-1 is expressed in human B-lymphocytes committed to the plasma cell lineage.

J Pathol 2005 May;206(1):76-86

Institute for Cancer Genetics, Columbia University, New York, NY 10032, USA.

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http://dx.doi.org/10.1002/path.1752DOI Listing
May 2005

Novel relational database for tissue microarray analysis.

Arch Pathol Lab Med 2003 Apr;127(4):492-4

Department of Pathology, New York Presbyterian Hospital, New York, NY, USA.

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http://dx.doi.org/10.1043/0003-9985(2003)127<0492:NRDFTM>2.0.CO;2DOI Listing
April 2003

A rare cause of nephrotic syndrome.

Am J Kidney Dis 2002 Apr;39(4):892-5

Department of Pathology, Columbia Presbyterian Medical Center, New York, NY 10032, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S027263860295934
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http://dx.doi.org/10.1053/ajkd.2002.32012DOI Listing
April 2002