Publications by authors named "Rita Sattler"

34Publications

Generation of two induced pluripotent stem cell (iPSC) lines from an ALS patient with simultaneous mutations in KIF5A and MATR3 genes.

Stem Cell Res 2020 Dec 24;50:102141. Epub 2020 Dec 24.

Department of Neurobiology, Gregory W Fulton ALS Research Center, Barrow Neurological Institute, 350 W Thomas Road, Phoenix, AZ 85013, USA.

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December 2020

The Hitchhiker's Guide to Nucleocytoplasmic Trafficking in Neurodegeneration.

Neurochem Res 2020 Jun 21;45(6):1306-1327. Epub 2020 Feb 21.

Department of Neurobiology, Barrow Neurological Institute, 350 W Thomas Road, Phoenix, AZ, 85013, USA.

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June 2020

Reactivation of nonsense-mediated mRNA decay protects against C9orf72 dipeptide-repeat neurotoxicity.

Brain 2019 05;142(5):1349-1364

Institute of Neuroscience, State Key Laboratory of Neuroscience, Key Laboratory of Primate Neurobiology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.

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May 2019

RNA Editing Deficiency in Neurodegeneration.

Adv Neurobiol 2018 ;20:63-83

Department of Neurobiology and Neurology, Dignityhealth St. Joseph's Hospital, Barrow Neurological Institute, Phoenix, AZ, USA.

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October 2018

Representing Diversity in the Dish: Using Patient-Derived Models to Recreate the Heterogeneity of Neurological Disease.

Front Neurosci 2018 9;12:56. Epub 2018 Feb 9.

Department of Neurobiology, Barrow Neurological Institute, Dignity Health-St. Joseph's Hospital and Medical Center, Phoenix, AZ, United States.

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February 2018

Synaptic dysfunction and altered excitability in C9ORF72 ALS/FTD.

Brain Res 2018 08 14;1693(Pt A):98-108. Epub 2018 Feb 14.

Division of Neurobiology, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ 85013, United States. Electronic address:

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August 2018

Post-transcriptional Inhibition of Hsc70-4/HSPA8 Expression Leads to Synaptic Vesicle Cycling Defects in Multiple Models of ALS.

Cell Rep 2017 Oct;21(1):110-125

Department of Molecular and Cellular Biology, University of Arizona, Tucson, AZ 85721, USA; Department of Neuroscience, University of Arizona, Tucson, AZ 85721, USA; Department of Neurology, University of Arizona, Tucson, AZ 85721, USA. Electronic address:

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October 2017

The transcription factor Pax6 contributes to the induction of GLT-1 expression in astrocytes through an interaction with a distal enhancer element.

J Neurochem 2016 Jan 24;136(2):262-75. Epub 2015 Nov 24.

Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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January 2016

High-Throughput Assay Development for Cystine-Glutamate Antiporter (xc-) Highlights Faster Cystine Uptake than Glutamate Release in Glioma Cells.

PLoS One 2015 7;10(8):e0127785. Epub 2015 Aug 7.

Brain Science Institute, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, United States of America; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, United States of America; Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, United States of America; Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, United States of America.

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May 2016

A comprehensive library of familial human amyotrophic lateral sclerosis induced pluripotent stem cells.

PLoS One 2015 11;10(3):e0118266. Epub 2015 Mar 11.

Department of Neurology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, 21205, United States of America; Brain Science Institute, Johns Hopkins University, Baltimore, Maryland, 21205, United States of America; Department of Neuroscience, Johns Hopkins University, School of Medicine, Baltimore, Maryland, 21205, United States of America.

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December 2015

Aberrant RNA homeostasis in amyotrophic lateral sclerosis: potential for new therapeutic targets?

Neurodegener Dis Manag 2014 ;4(6):417-37

Brain Science Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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August 2015

Biomarker development for C9orf72 repeat expansion in ALS.

Brain Res 2015 May 27;1607:26-35. Epub 2014 Sep 27.

Brain Science Institute and Department of Neurology, Johns Hopkins University School of Medicine, 855N Wolfe Street, Rangos 2-223, Baltimore, MD 21205, USA. Electronic address:

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May 2015

Mutant disrupted-in-schizophrenia 1 in astrocytes: focus on glutamate metabolism.

J Neurosci Res 2014 Dec 8;92(12):1659-68. Epub 2014 Aug 8.

Departments of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland.

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December 2014

C9orf72 nucleotide repeat structures initiate molecular cascades of disease.

Nature 2014 Mar 5;507(7491):195-200. Epub 2014 Mar 5.

1] Department of Biochemistry and Molecular Biology, Johns Hopkins University Baltimore, Maryland 21205, USA [2] Department of Neuroscience, Johns Hopkins University Baltimore, Maryland 21205, USA.

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March 2014

RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention.

Neuron 2013 Oct;80(2):415-28

Department of Neurology, Johns Hopkins University, 855 N Wolfe Street, Rangos 2-270, Baltimore, MD 21205, USA; Brain Science Institute, Johns Hopkins University, 855 N Wolfe Street, Rangos 2-270, Baltimore, MD 21205, USA.

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October 2013

Human nasal olfactory epithelium as a dynamic marker for CNS therapy development.

Exp Neurol 2011 Dec 16;232(2):203-11. Epub 2011 Sep 16.

Department of Neurology, Johns Hopkins University, Baltimore, MD 21205, USA.

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December 2011

Inhibition of xc⁻ transporter-mediated cystine uptake by sulfasalazine analogs.

Bioorg Med Chem Lett 2011 Oct 12;21(20):6184-7. Epub 2011 Aug 12.

Department of Neurology, Johns Hopkins University, Baltimore, MD 21205, USA.

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October 2011

Genetic and functional studies of a missense variant in a glutamate transporter, SLC1A3, in Tourette syndrome.

Psychiatr Genet 2011 Apr;21(2):90-7

McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

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April 2011

Harmine, a natural beta-carboline alkaloid, upregulates astroglial glutamate transporter expression.

Neuropharmacology 2011 Jun 27;60(7-8):1168-75. Epub 2010 Oct 27.

Department of Neurology, Johns Hopkins University, School of Medicine, Baltimore, MD 21205, USA.

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June 2011

GluR1 controls dendrite growth through its binding partner, SAP97.

J Neurosci 2008 Oct;28(41):10220-33

Department of Pediatrics, Division of Neurology, Joseph Stokes Jr. Research Institute, Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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October 2008

Targeting an old mechanism in a new disease-protection of glutamatergic dysfunction in depression.

Biol Psychiatry 2007 Jan;61(2):137-8

Department of Neurology, Johns Hopkins University, Baltimore, MD 21287, USA.

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January 2007

Persistent hippocampal CA1 LTP in mice lacking the C-terminal PDZ ligand of GluR1.

Nat Neurosci 2005 Aug 10;8(8):985-7. Epub 2005 Jul 10.

Department of Neuroscience and Howard Hughes Medical Institute, The Johns Hopkins University, Baltimore, Maryland 21205, USA.

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August 2005

Formation of polypyrrole from 2,5-bis(2-pyrrolyl)pyrrolidine.

Chem Commun (Camb) 2004 Feb 13(3):344-5. Epub 2004 Jan 13.

Department of Chemistry, Memorial University of Newfoundland, St. John's, Newfoundland, Canada A1B 3X7.

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February 2004