Rita Chiari

Rita Chiari

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Rita Chiari

Rita Chiari

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Texture Analysis on [F]FDG PET/CT in Non-Small-Cell Lung Cancer: Correlations Between PET Features, CT Features, and Histological Types.

Mol Imaging Biol 2019 12;21(6):1200-1209

Section of Nuclear Medicine and Health Physics, Department of Surgical and Biomedical Sciences, Università degli Studi di Perugia, Piazza Lucio Severi 1, 06132, Perugia, Italy.

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http://dx.doi.org/10.1007/s11307-019-01336-3DOI Listing
December 2019

Antibody-drug conjugates for lung cancer in the era of personalized oncology.

Semin Cancer Biol 2019 Dec 30. Epub 2019 Dec 30.

Unit of Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Medicine, University of Perugia, Perugia, 06129, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.semcancer.2019.12.024DOI Listing
December 2019

Safety and Efficacy of Nivolumab in Patients With Advanced Non-small-cell Lung Cancer Treated Beyond Progression.

Clin Lung Cancer 2019 05 27;20(3):178-185.e2. Epub 2019 Feb 27.

Medical Oncology, Thoracic Oncology Unit, Santa Maria della Misericordia Hospital, University of Perugia, Perugia, Italy.

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http://dx.doi.org/10.1016/j.cllc.2019.02.001DOI Listing
May 2019

Targeting indoleamine-2,3-dioxygenase in cancer: Scientific rationale and clinical evidence.

Pharmacol Ther 2019 04 4;196:105-116. Epub 2018 Dec 4.

Unit of Internal Medicine, Department of Medicine, University of Perugia, Perugia, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01637258183022
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http://dx.doi.org/10.1016/j.pharmthera.2018.12.004DOI Listing
April 2019

Afatinib in the first-line treatment of patients with non-small cell lung cancer: clinical evidence and experience.

Ther Adv Respir Dis 2018 Jan-Dec;12:1753466618808659

Department of Medical Oncology, Santa Maria della Misericordia Hospital, University of Perugia, Piazzale Menghini, Perugia, Italy.

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http://journals.sagepub.com/doi/10.1177/1753466618808659
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http://dx.doi.org/10.1177/1753466618808659DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204616PMC
March 2019

A Brief Report of Transformation From NSCLC to SCLC: Molecular and Therapeutic Characteristics.

J Thorac Oncol 2019 01 11;14(1):130-134. Epub 2018 Sep 11.

Thoracic Oncology unit, PTV, CHU Grenoble CS10217-38043 Grenoble cedex 9, France et INSERM U 823. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2018.08.2028DOI Listing
January 2019

Osimertinib.

Recent Results Cancer Res 2018;211:257-276

Medical Oncology, Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia, via Dottori, 1, 06156, Perugia, Italy.

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http://dx.doi.org/10.1007/978-3-319-91442-8_18DOI Listing
November 2018

Early stage resectable non-small cell lung cancer: is neoadjuvant immunotherapy the right way forward?

J Thorac Dis 2018 Nov;10(Suppl 33):S3890-S3894

Medical Oncology, Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia, Perugia, Italy.

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http://dx.doi.org/10.21037/jtd.2018.10.22DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297455PMC
November 2018

Successful Response to Osimertinib Rechallenge after Intervening Chemotherapy in an EGFR T790M-Positive Lung Cancer Patient.

Clin Drug Investig 2018 Oct;38(10):983-987

Anatomic Pathology and Histology Section, Department of Experimental Medicine, University of Perugia, Perugia, Italy.

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http://link.springer.com/10.1007/s40261-018-0691-8
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http://dx.doi.org/10.1007/s40261-018-0691-8DOI Listing
October 2018

Dramatic Response to Lorlatinib in a Heavily Pretreated Lung Adenocarcinoma Patient Harboring G1202R Mutation and a Synchronous Novel R1192P ALK Point Mutation.

J Thorac Oncol 2018 08;13(8):e145-e147

Medical Oncology, Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia, Perugia, Italy.

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http://dx.doi.org/10.1016/j.jtho.2018.03.017DOI Listing
August 2018

Precision medicine against ALK-positive non-small cell lung cancer: beyond crizotinib.

Med Oncol 2018 Apr 17;35(5):72. Epub 2018 Apr 17.

Department of Medical Oncology, Santa Maria della Misericordia Hospital, University of Perugia, Piazzale L. Severi n. 1, 06132, Perugia, Italy.

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http://dx.doi.org/10.1007/s12032-018-1133-4DOI Listing
April 2018

Anaplastic lymphoma kinase immunohistochemistry scores do not predict sensitivity to crizotinib in fluorescence in situ hybridization-positive non-small cell lung cancer patients.

Int J Biol Markers 2018 Apr 1:1724600818754763. Epub 2018 Apr 1.

3 Section of Anatomic Pathology and Histology, Department of Experimental Medicine, University of Perugia Medical School, Perugia, Italy.

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http://dx.doi.org/10.1177/1724600818754763DOI Listing
April 2018

First line osimertinib for the treatment of patients with advanced EGFR-mutant NSCLC.

Transl Lung Cancer Res 2018 Apr;7(Suppl 2):S127-S130

Department of Medical Oncology, Santa Maria della Misericordia Hospital, University of Perugia, Perugia, Italy.

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http://dx.doi.org/10.21037/tlcr.2018.03.06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943230PMC
April 2018

Fatal acute disseminated intravascular coagulation as presentation of advanced ALK-positive non-small cell lung cancer: Does oncogene addiction matter?

Thromb Res 2018 03 9;163:51-53. Epub 2017 Dec 9.

Department of Medical Oncology, Santa Maria della Misericordia Hospital, University of Perugia, Piazzale L. Severi n. 1, 06132 Perugia, Italy.

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http://dx.doi.org/10.1016/j.thromres.2017.12.004DOI Listing
March 2018

Targeting NTRK fusion in non-small cell lung cancer: rationale and clinical evidence.

Med Oncol 2017 Jun 25;34(6):105. Epub 2017 Apr 25.

Department of Medical Oncology, Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia, Via Dottori, 1, 06156, Perugia, Italy.

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http://dx.doi.org/10.1007/s12032-017-0967-5DOI Listing
June 2017

Italian, Multicenter, Phase III, Randomized Study of Cisplatin Plus Etoposide With or Without Bevacizumab as First-Line Treatment in Extensive-Disease Small-Cell Lung Cancer: The GOIRC-AIFA FARM6PMFJM Trial.

J Clin Oncol 2017 Apr 30;35(12):1281-1287. Epub 2017 Jan 30.

Marcello Tiseo, Azienda Ospedaliero-Universitaria, Parma; Luca Boni, Clinical Trials Coordinating Center, Istituto Toscano Tumori, Azienda Ospedaliero-Universitaria Careggi, Firenze; Francesca Ambrosio and Ferdinando Riccardi, Azienda Ospedaliera di Rilievo Nazionale Cardarelli, Napoli; Andrea Camerini, Ospedale della Versilia, Lido di Camaiore; Editta Baldini and Carmelo Tibaldi, Ospedale San Luca, Lucca; Saverio Cinieri, Ospedale Perrino, Brindisi; Matteo Brighenti, Azienda Socio-Sanitaria Territoriale di Cremona, Cremona; Francesca Zanelli, Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS), Ospedale Santa Maria Nuova, Reggio Emilia; Efisio Defraia, Ospedale Businco, Cagliari; Rita Chiari, Azienda Ospedaliero-Universitaria, Perugia; Claudio Dazzi, Ospedale Santa Maria delle Croci, Ravenna; Gianni Michele Turolla, Ospedale Civile Umberto I, Lugo di Romagna; Vito D'Alessandro, IRCCS Ospedale Casa Sollievo della Sofferenza, San Giovanni Rotondo; Nicoletta Zilembo, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano; Anna Rita Trolese, Ospedale Mater Salutis di Legnago, Legnago; Francesco Grossi, Azienda Ospedaliera Universitaria San Martino IST-Istituto Nazionale per la Ricerca sul Cancro, Genova; and Andrea Ardizzoni, Azienda Ospedaliero-Universitaria Sant'Orsola Malpighi, Bologna, Italy.

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http://dx.doi.org/10.1200/JCO.2016.69.4844DOI Listing
April 2017

Optimal management of ALK-positive NSCLC progressing on crizotinib.

Lung Cancer 2017 04 6;106:58-66. Epub 2017 Feb 6.

Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola (FC), Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S01695002173003
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http://dx.doi.org/10.1016/j.lungcan.2017.02.003DOI Listing
April 2017

The safety of nivolumab for the treatment of advanced non-small cell lung cancer.

Expert Opin Drug Saf 2017 Jan 11;16(1):101-109. Epub 2016 Dec 11.

a Medical Oncology , Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia , Perugia , Italy.

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https://www.tandfonline.com/doi/full/10.1080/14740338.2017.1
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http://dx.doi.org/10.1080/14740338.2017.1267725DOI Listing
January 2017

Preface on "Emerging treatment options for brain metastases from non-small cell lung cancer".

Transl Lung Cancer Res 2016 Dec;5(6):561-562

Division of Medical Oncology, Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia, 06156 Perugia, Italy. (Email: ; ).

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http://dx.doi.org/10.21037/tlcr.2016.12.04DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233885PMC
December 2016

Malignant giant solitary fibrous tumor of the pleura metastatic to the thyroid gland.

Tumori 2016 Nov 11;102(Suppl. 2). Epub 2016 Nov 11.

Department of Medical Oncology, Santa Maria della Misericordia Hospital, Perugia - Italy.

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http://dx.doi.org/10.5301/tj.5000514DOI Listing
November 2016

How might treatment of ALK-positive non-small cell lung cancer change in the near future?

Expert Rev Anticancer Ther 2016 10 25;16(10):997-9. Epub 2016 Aug 25.

a Medical Oncology , Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia , Perugia , Italy.

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http://dx.doi.org/10.1080/14737140.2016.1226138DOI Listing
October 2016

Alectinib's activity against CNS metastases from ALK-positive non-small cell lung cancer: a single institution case series.

J Neurooncol 2016 09 20;129(2):355-61. Epub 2016 Jun 20.

Medical Oncology, Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia, via Dottori, 1, 06156, Perugia, Italy.

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http://dx.doi.org/10.1007/s11060-016-2184-zDOI Listing
September 2016

Efficacy and safety of rechallenge treatment with gefitinib in patients with advanced non-small cell lung cancer.

Lung Cancer 2016 09 14;99:31-7. Epub 2016 Jun 14.

Thoracic Oncology Division, Istituto Europeo di Oncologia (IEO), Via Ripamonti 435, 20141 Milan, Italy, Italy; Formerly Department of Thoracic Oncology, 1st Pulmonary Oncological Unit, Azienda Ospedaliera San Camillo-Forlanini, Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2016.06.008DOI Listing
September 2016

Osimertinib (AZD9291) and CNS Response in Two Radiotherapy-Naïve Patients with EGFR-Mutant and T790M-Positive Advanced Non-Small Cell Lung Cancer.

Clin Drug Investig 2016 Aug;36(8):683-6

Department of Medical Oncology, Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia, via Dottori 1, 06156, Perugia, Italy.

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http://dx.doi.org/10.1007/s40261-016-0411-1DOI Listing
August 2016

Pharmacotherapeutic options for treating brain metastases in non-small cell lung cancer.

Expert Opin Pharmacother 2015 6;16(17):2601-13. Epub 2015 Oct 6.

a 1 Medical Oncology, Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia , Perugia, Italy +39 07 55 78 41 85 ; +39 07 55 78 41 84 ;

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http://dx.doi.org/10.1517/14656566.2015.1094056DOI Listing
June 2016

Long noncoding RNAs: new insights into non-small cell lung cancer biology, diagnosis and therapy.

Med Oncol 2016 Feb 19;33(2):18. Epub 2016 Jan 19.

Medical Oncology, Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia, Via Dottori 1, 06156, Perugia, Italy.

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http://dx.doi.org/10.1007/s12032-016-0731-2DOI Listing
February 2016

Incidence of Ct scan-detected pulmonary embolism in patients with oncogene-addicted, advanced lung adenocarcinoma.

Thromb Res 2015 Nov 9;136(5):924-7. Epub 2015 Sep 9.

Internal and Cardiovascular Medicine-Stroke Unit, University of Perugia, Perugia, Italy.

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http://dx.doi.org/10.1016/j.thromres.2015.09.006DOI Listing
November 2015

Early Prediction of Response to Tyrosine Kinase Inhibitors by Quantification of EGFR Mutations in Plasma of NSCLC Patients.

J Thorac Oncol 2015 Oct;10(10):1437-43

*Center of Predictive Molecular Medicine, Ce.S.I., G. D'Annunzio University-Foundation, Chieti, Italy; †Medical Scientific Affairs Department, Roche Molecular Systems, Pleasanton, California; ‡Oncological and Cardiovascular Molecular Medicine Unit, Ce.S.I., G. D'Annunzio University-Foundation, Chieti, Italy; §Division of Thoracic Oncology, European Institute of Oncology, Milan, Italy; ‖Department of Medical Oncology, S. Maria della Misericordia Hospital, Perugia, Italy; ¶Department of Medical Oncology, Bellaria-Maggiore Hospital, Azienda USL of Bologna, Bologna, Italy; #Unit of Pneumology, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy; **Ospedale Civile di Pescara, Pescara, Italy; ††Ospedale Civile di Sulmona, Sulmona, Italy; ‡‡Department of Medical Oncology, Consorzio Interuniversitario Nazionale per la Bio-Oncologia, G. d'Annunzio University, Chieti, Italy; §§Department of Oncology-Haematology, Humanitas Cancer Center, IRCCS, Milan, Italy; and ‖‖Perugia University Medical School, Perugia, Italy.

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http://dx.doi.org/10.1097/JTO.0000000000000643DOI Listing
October 2015

c-Met targeting in advanced gastric cancer: An open challenge.

Cancer Lett 2015 Aug 3;365(1):30-6. Epub 2015 Jun 3.

General, Minimally Invasive and Robotic Surgery, Department of Surgery, "San Matteo degli Infermi" Hospital, ASL Umbria 2, 06049 Spoleto, Italy.

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http://dx.doi.org/10.1016/j.canlet.2015.05.028DOI Listing
August 2015

Bronchiolitis obliterans organizing pneumonia after radiation therapy for lung cancer: a case report.

Tumori 2015 Jun 25;101(3):e88-91. Epub 2015 Jun 25.

1 Radiation Oncology Division, Perugia General Hospital, Perugia - Italy.

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http://dx.doi.org/10.5301/TJ.2015.14508DOI Listing
June 2015

CSF Concentration of Crizotinib in Two ALK-Positive Non-Small-Cell Lung Cancer Patients with CNS Metastases Deriving Clinical Benefit from Treatment.

J Thorac Oncol 2015 May;10(5):e26-7

*Medical Oncology, Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia, Perugia, Italy; †Medical Oncology, Sacro Cuore-Don Calabria Hospital, Negrar, VR, Italy; ‡Neuroradiology, Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia, Perugia, Italy; and §dto-LABS, Agilent Partner Lab, Resana, TV, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S15560864153240
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http://dx.doi.org/10.1097/JTO.0000000000000468DOI Listing
May 2015

Future options for ALK-positive non-small cell lung cancer.

Lung Cancer 2015 Mar 3;87(3):211-9. Epub 2015 Jan 3.

Medical Oncology, Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia, Perugia, Italy.

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http://dx.doi.org/10.1016/j.lungcan.2014.12.017DOI Listing
March 2015

Selumetinib: a promising pharmacologic approach for KRAS-mutant advanced non-small-cell lung cancer.

Future Oncol 2013 Feb;9(2):167-77

Division of Medical Oncology, Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia, via Dottori 1, 06156 Perugia, Italy.

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http://dx.doi.org/10.2217/fon.12.198DOI Listing
February 2013

Primary and metastatic brain tumors.

Forum (Genova) 2006 ;14(1):E2

Medical Oncology, Bellaria Hospital, Bologna, Italy.

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August 2010