Publications by authors named "Rio S Boothello"

10Publications

Visualizing antithrombin-binding 3--sulfated heparan sulfate motifs on cell surfaces.

Chem Commun (Camb) 2020 Nov;56(92):14423-14426

Departments of Medicinal Chemistry and Bioengineering, University of Utah, Salt Lake City, UT 84112, USA.

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http://dx.doi.org/10.1039/d0cc05893aDOI Listing
November 2020

Studies on fragment-based design of allosteric inhibitors of human factor XIa.

Bioorg Med Chem 2020 Sep 13;28(23):115762. Epub 2020 Sep 13.

Department of Medicinal Chemistry, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298, United States; Institute for Structural Biology, Drug Discovery and Development, Virginia Commonwealth University, Richmond, VA 23219, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2020.115762DOI Listing
September 2020

A Unique Nonsaccharide Mimetic of Heparin Hexasaccharide Inhibits Colon Cancer Stem Cells via p38 MAP Kinase Activation.

Mol Cancer Ther 2019 01 18;18(1):51-61. Epub 2018 Oct 18.

Division of Hematology and Oncology, Department of Internal Medicine, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia.

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http://dx.doi.org/10.1158/1535-7163.MCT-18-0104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332501PMC
January 2019

A small group of sulfated benzofurans induces steady-state submaximal inhibition of thrombin.

Bioorg Med Chem Lett 2018 04 3;28(6):1101-1105. Epub 2018 Feb 3.

Department of Medicinal Chemistry, Virginia Commonwealth University, Richmond, VA, USA; Institute for Structural Biology, Drug Discovery and Development, Virginia Commonwealth University, Richmond, VA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2018.01.069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851871PMC
April 2018

A Hexasaccharide Containing Rare 2-O-Sulfate-Glucuronic Acid Residues Selectively Activates Heparin Cofactor II.

Angew Chem Int Ed Engl 2017 02 26;56(9):2312-2317. Epub 2017 Jan 26.

Department of Medicinal Chemistry and Institute of Structural Biology, Drug Discovery and Development, Virginia Commonwealth University, Richmond, VA, USA.

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http://dx.doi.org/10.1002/anie.201609541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347859PMC
February 2017

Glycosaminoglycan-protein interaction studies using fluorescence spectroscopy.

Methods Mol Biol 2015 ;1229:335-53

Department of Medicinal Chemistry and Institute for Structural Biology and Drug Discovery, Virginia Commonwealth University, 800 E. Leigh Street, Suite 212, Richmond, VA, 23219, USA.

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http://dx.doi.org/10.1007/978-1-4939-1714-3_27DOI Listing
June 2015

Interaction of thrombin with sucrose octasulfate.

Biochemistry 2011 Aug 18;50(32):6973-82. Epub 2011 Jul 18.

Departments of Medicinal Chemistry and Biochemistry and Institute for Structural Biology and Drug Discovery, Virginia Commonwealth University, Richmond, Virginia 23219, United States.

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http://dx.doi.org/10.1021/bi2004526DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172994PMC
August 2011