Rimpei Morita

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Rimpei Morita

Publications by authors named "Rimpei Morita"

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50Publications

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Generation and application of human induced-stem cell memory T (iT ) cells for adoptive immunotherapy.

Cancer Sci 2018 May 23. Epub 2018 May 23.

Department of Microbiology and Immunology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.

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May 2018

Notch-mediated conversion of activated T cells into stem cell memory-like T cells for adoptive immunotherapy.

Nat Commun 2017 May 22;8:15338. Epub 2017 May 22.

Department of Microbiology and Immunology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.

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May 2017

Innate-like function of memory Th17 cells for enhancing endotoxin-induced acute lung inflammation through IL-22.

Int Immunol 2016 05 8;28(5):233-43. Epub 2015 Dec 8.

Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo 160-8582, Japan

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May 2016

Identification of definitive serum biomarkers associated with disease activity in primary Sjögren's syndrome.

Arthritis Res Ther 2016 05 14;18(1):106. Epub 2016 May 14.

Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.

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May 2016

Resolution of elevated circulating regulatory T cells by corticosteroids in patients with IgG4-related dacryoadenitis and sialoadenitis.

Int J Rheum Dis 2016 Apr 19;19(4):430-2. Epub 2015 Sep 19.

Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.

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April 2016

Serum proteomic analysis identifies interleukin 16 as a biomarker for clinical response during early treatment of rheumatoid arthritis.

Cytokine 2016 Feb 14;78:87-93. Epub 2015 Dec 14.

Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8552, Japan. Electronic address:

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February 2016

Suppression of Th2 and Tfh immune reactions by Nr4a receptors in mature T reg cells.

J Exp Med 2015 Sep 24;212(10):1623-40. Epub 2015 Aug 24.

Department of Microbiology and Immunology, Keio University School of Medicine, Shinjuku-ku, Tokyo 160-8582, Japan Japan Science and Technology Agency (JST), Core Research for Evolutional Science and Technology, Chiyoda-ku, Tokyo 102-0075, Japan

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September 2015

Spred1, a Suppressor of the Ras-ERK Pathway, Negatively Regulates Expansion and Function of Group 2 Innate Lymphoid Cells.

J Immunol 2015 Aug 26;195(3):1273-81. Epub 2015 Jun 26.

Department of Microbiology and Immunology, Keio University School of Medicine, Shinjuku-ku, Tokyo 160-8582, Japan; Japan Science and Technology Agency, CREST, Chiyoda-ku, Tokyo 102-0075, Japan; and

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August 2015

Polarization diversity of human CD4+ stem cell memory T cells.

Clin Immunol 2015 Jul 27;159(1):107-17. Epub 2015 Apr 27.

Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan. Electronic address:

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July 2015

Smad2 and Smad3 Inversely Regulate TGF-β Autoinduction in Clostridium butyricum-Activated Dendritic Cells.

Immunity 2015 Jul 30;43(1):65-79. Epub 2015 Jun 30.

Department of Microbiology and Immunology, Department of Internal Medicine, Keio University School of Medicine, Tokyo 160-8582, Japan, and Japan Science and Technology Agency, CREST, Tokyo 102-0076, Japan. Electronic address:

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July 2015

AMCase is a crucial regulator of type 2 immune responses to inhaled house dust mites.

Proc Natl Acad Sci U S A 2015 Jun 18;112(22):E2891-9. Epub 2015 May 18.

Department of Immunobiology, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06520

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June 2015

Bruton's tyrosine kinase is essential for NLRP3 inflammasome activation and contributes to ischaemic brain injury.

Nat Commun 2015 Jun 10;6:7360. Epub 2015 Jun 10.

1] Department of Microbiology and Immunology, Keio University School of Medicine, Shinjuku-ku, Tokyo 160-8582, Japan [2] Japan Science and Technology Agency (JST), CREST, Chiyoda-ku, Tokyo 102-0075, Japan.

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June 2015

ETS transcription factor ETV2 directly converts human fibroblasts into functional endothelial cells.

Proc Natl Acad Sci U S A 2015 Jan 24;112(1):160-5. Epub 2014 Dec 24.

Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo 160-8582, Japan; Core Research for Evolutional Science and Technology Program, Japan Science and Technology Agency, Tokyo 102-0076, Japan;

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January 2015

Prevention of allogeneic cardiac graft rejection by transfer of ex vivo expanded antigen-specific regulatory T-cells.

PLoS One 2014 3;9(2):e87722. Epub 2014 Feb 3.

Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan ; Japan Science and Technology Agency, CREST, Tokyo, Japan.

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October 2014

TRAF6 is essential for maintenance of regulatory T cells that suppress Th2 type autoimmunity.

PLoS One 2013 13;8(9):e74639. Epub 2013 Sep 13.

Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan.

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June 2014

Aryl hydrocarbon receptor protects against bacterial infection by promoting macrophage survival and reactive oxygen species production.

Int Immunol 2014 Apr 16;26(4):209-20. Epub 2013 Dec 16.

Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo 160-8582, Japan.

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April 2014

Th17 cells carrying TCR recognizing epidermal autoantigen induce psoriasis-like skin inflammation.

J Immunol 2013 Sep 16;191(6):3065-72. Epub 2013 Aug 16.

Department of Microbiology and Immunology, Keio University School of Medicine, Shinjyuku-ku, Tokyo 160-8582, Japan.

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September 2013

Nr4a receptors are essential for thymic regulatory T cell development and immune homeostasis.

Nat Immunol 2013 Mar 20;14(3):230-7. Epub 2013 Jan 20.

Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan.

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March 2013

Smad2 and Smad3 are redundantly essential for the suppression of iNOS synthesis in macrophages by regulating IRF3 and STAT1 pathways.

Int Immunol 2012 Apr 13;24(4):253-65. Epub 2012 Feb 13.

Department of Microbiology and Immunology, Keio University School of Medicine, Shinjuku-ku, Tokyo 160-8582, Japan.

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April 2012

Low dose CP-690,550 (tofacitinib), a pan-JAK inhibitor, accelerates the onset of experimental autoimmune encephalomyelitis by potentiating Th17 differentiation.

Biochem Biophys Res Commun 2012 Feb 9;418(2):234-40. Epub 2012 Jan 9.

Department of Microbiology and Immunology, Keio University School of Medicine, Shinjuku-ku, Tokyo 160-8582, Japan.

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February 2012

Pyridone 6, a pan-JAK inhibitor, ameliorates allergic skin inflammation of NC/Nga mice via suppression of Th2 and enhancement of Th17.

J Immunol 2011 Nov 28;187(9):4611-20. Epub 2011 Sep 28.

Department of Microbiology and Immunology, Keio University School of Medicine, Shinjuku-ku, Tokyo 160-8582, Japan.

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November 2011

SOCS1 is essential for regulatory T cell functions by preventing loss of Foxp3 expression as well as IFN-{gamma} and IL-17A production.

J Exp Med 2011 Sep 5;208(10):2055-67. Epub 2011 Sep 5.

Department of Microbiology and Immunology, Keio University School of Medicine, Shinjyuku-ku, Tokyo 160-8582, Japan.

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September 2011

miR126 positively regulates mast cell proliferation and cytokine production through suppressing Spred1.

Genes Cells 2011 Jul 13;16(7):803-14. Epub 2011 Jun 13.

Department of Microbiology and Immunology, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.

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July 2011

Transcription factor Smad-independent T helper 17 cell induction by transforming-growth factor-β is mediated by suppression of eomesodermin.

Immunity 2011 May 19;34(5):741-54. Epub 2011 May 19.

Department of Microbiology and Immunology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, Japan.

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May 2011

SOCS1 regulates type I/type II NKT cell balance by regulating IFNgamma signaling.

Int Immunol 2011 Mar;23(3):165-76

Division of Molecular and Cellular Immunology, Medical Institute of Bioregulation, Kyushu University, Fukuoka 812-8582, Japan.

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March 2011

Prostaglandin E2 and SOCS1 have a role in intestinal immune tolerance.

Nat Commun 2011 Feb 8;2:190. Epub 2011 Feb 8.

Department of Microbiology and Immunology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.

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February 2011

Harnessing human dendritic cell subsets to design novel vaccines.

Ann N Y Acad Sci 2009 Sep;1174:24-32

Baylor Institute for Immunology Research, Dallas, TX 75204, USA.

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September 2009

Human plasmacytoid dendritic cells express an atrial natriuretic peptide receptor, guanylyl cyclase-A.

Microbiol Immunol 2009 Jul;53(7):403-11

Department of Hematology and Oncology, Kyoto University, Sakyo-ku, Kyoto 606-8507, Japan.

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July 2009

A T cell-dependent mechanism for the induction of human mucosal homing immunoglobulin A-secreting plasmablasts.

Immunity 2009 Jan;30(1):120-9

Baylor Institute for Immunology Research, Baylor Research Institute and INSERM 899, Dallas, TX 75204, USA.

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January 2009

Delineation of immunoregulatory properties of adult T-cell leukemia cells.

Int J Hematol 2006 Jul;84(1):63-9

Department of Hematology and Oncology, Graduate School of Medicine, Kyoto, Japan.

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July 2006

Nitric oxide inhibits IFN-alpha production of human plasmacytoid dendritic cells partly via a guanosine 3',5'-cyclic monophosphate-dependent pathway.

J Immunol 2005 Jul;175(2):806-12

Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, 50 Shogoin Kawara-cho, Sayko-ku, Kyoto 606-8507, Japan.

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July 2005

Atrial natriuretic peptide polarizes human dendritic cells toward a Th2-promoting phenotype through its receptor guanylyl cyclase-coupled receptor A.

J Immunol 2003 Jun;170(12):5869-75

Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

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June 2003